Incidental Mutation 'R8181:Helz'
| ID |
634634 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Helz
|
| Ensembl Gene |
ENSMUSG00000020721 |
| Gene Name |
helicase with zinc finger domain |
| Synonyms |
3110078M01Rik, 9430093I07Rik, 9630002H22Rik |
| MMRRC Submission |
067605-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8181 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
107438756-107584652 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 107563399 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1613
(D1613G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074533
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075012]
[ENSMUST00000100305]
[ENSMUST00000106746]
[ENSMUST00000133862]
|
| AlphaFold |
Q6DFV5 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000075012
AA Change: D1613G
|
| SMART Domains |
Protein: ENSMUSP00000074533
Gene: ENSMUSG00000020721
AA Change: D1613G
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:ResIII
|
639 |
807 |
6.7e-8 |
PFAM |
|
Pfam:AAA_11
|
641 |
768 |
2.3e-14 |
PFAM |
|
Pfam:AAA_30
|
641 |
838 |
2.6e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
729 |
5.5e-11 |
PFAM |
|
Pfam:AAA_11
|
758 |
834 |
3.8e-18 |
PFAM |
|
Pfam:AAA_12
|
841 |
1053 |
7.4e-38 |
PFAM |
|
low complexity region
|
1165 |
1176 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1448 |
N/A |
INTRINSIC |
|
low complexity region
|
1466 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1557 |
1568 |
N/A |
INTRINSIC |
|
low complexity region
|
1631 |
1647 |
N/A |
INTRINSIC |
|
low complexity region
|
1716 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
1926 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1942 |
1957 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100305
|
| SMART Domains |
Protein: ENSMUSP00000097878
Gene: ENSMUSG00000020721
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
2.7e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
1.7e-10 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
6.3e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
3.4e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000106746
AA Change: D1612G
|
| SMART Domains |
Protein: ENSMUSP00000102357
Gene: ENSMUSG00000020721
AA Change: D1612G
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
1e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
8.3e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
2.2e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
1.7e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
low complexity region
|
1630 |
1646 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1735 |
N/A |
INTRINSIC |
|
low complexity region
|
1925 |
1932 |
N/A |
INTRINSIC |
|
low complexity region
|
1941 |
1956 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000133862
|
| SMART Domains |
Protein: ENSMUSP00000117498
Gene: ENSMUSG00000020721
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AAA_11
|
68 |
152 |
2.1e-19 |
PFAM |
|
Pfam:AAA_12
|
159 |
371 |
1.5e-36 |
PFAM |
|
low complexity region
|
483 |
494 |
N/A |
INTRINSIC |
|
low complexity region
|
678 |
766 |
N/A |
INTRINSIC |
|
low complexity region
|
784 |
805 |
N/A |
INTRINSIC |
|
low complexity region
|
875 |
886 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.3%
|
| Validation Efficiency |
100% (73/73) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene-trapped allele are viable, fertile and phenotypically normal with no apparent skeletal defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
G |
A |
3: 137,774,156 (GRCm39) |
S1115N |
probably damaging |
Het |
| Abca1 |
A |
G |
4: 53,059,303 (GRCm39) |
V1551A |
probably benign |
Het |
| Adam30 |
T |
C |
3: 98,070,291 (GRCm39) |
I708T |
probably benign |
Het |
| Aknad1 |
T |
A |
3: 108,659,328 (GRCm39) |
L114H |
possibly damaging |
Het |
| Akr1c18 |
G |
A |
13: 4,185,262 (GRCm39) |
S290L |
probably benign |
Het |
| Aldh18a1 |
G |
T |
19: 40,545,881 (GRCm39) |
D635E |
probably benign |
Het |
| Bax |
G |
T |
7: 45,115,698 (GRCm39) |
P23Q |
probably null |
Het |
| Bhlha15 |
A |
T |
5: 144,128,244 (GRCm39) |
N119Y |
probably damaging |
Het |
| Boll |
T |
A |
1: 55,402,478 (GRCm39) |
M1L |
probably benign |
Het |
| C2cd2 |
A |
T |
16: 97,693,502 (GRCm39) |
I123N |
probably benign |
Het |
| Cacnb4 |
A |
C |
2: 52,364,997 (GRCm39) |
S89A |
probably benign |
Het |
| Calca |
A |
G |
7: 114,234,387 (GRCm39) |
C21R |
probably benign |
Het |
| Calcr |
T |
C |
6: 3,693,899 (GRCm39) |
I325M |
probably benign |
Het |
| Card14 |
T |
A |
11: 119,212,718 (GRCm39) |
F94Y |
probably damaging |
Het |
| Chil3 |
A |
C |
3: 106,057,203 (GRCm39) |
I247S |
probably damaging |
Het |
| Clca3b |
T |
C |
3: 144,544,898 (GRCm39) |
N363S |
probably benign |
Het |
| Cnksr3 |
A |
G |
10: 7,070,475 (GRCm39) |
V494A |
possibly damaging |
Het |
| Cog4 |
A |
G |
8: 111,578,717 (GRCm39) |
|
probably null |
Het |
| Crybg1 |
T |
A |
10: 43,862,322 (GRCm39) |
Y1484F |
probably damaging |
Het |
| Dglucy |
A |
G |
12: 100,816,370 (GRCm39) |
|
probably null |
Het |
| Dmp1 |
T |
A |
5: 104,359,380 (GRCm39) |
|
probably null |
Het |
| Dscaml1 |
T |
A |
9: 45,658,140 (GRCm39) |
I1637N |
possibly damaging |
Het |
| Ercc6 |
T |
A |
14: 32,279,905 (GRCm39) |
I640N |
probably damaging |
Het |
| Esp16 |
G |
T |
17: 39,850,707 (GRCm39) |
E29* |
probably null |
Het |
| Fam149a |
T |
C |
8: 45,834,755 (GRCm39) |
I15V |
possibly damaging |
Het |
| Flt4 |
T |
A |
11: 49,525,723 (GRCm39) |
I724N |
probably damaging |
Het |
| Glb1 |
C |
T |
9: 114,259,429 (GRCm39) |
R202C |
probably damaging |
Het |
| Gmpr2 |
C |
A |
14: 55,910,441 (GRCm39) |
S41* |
probably null |
Het |
| Golgb1 |
T |
A |
16: 36,737,192 (GRCm39) |
D2187E |
probably damaging |
Het |
| Gpsm2 |
A |
G |
3: 108,597,080 (GRCm39) |
|
probably null |
Het |
| Hemgn |
A |
C |
4: 46,396,504 (GRCm39) |
M244R |
possibly damaging |
Het |
| Hsd3b1 |
A |
T |
3: 98,763,453 (GRCm39) |
V56E |
probably damaging |
Het |
| Jup |
A |
T |
11: 100,267,751 (GRCm39) |
I524N |
probably damaging |
Het |
| Kdm1b |
G |
T |
13: 47,205,377 (GRCm39) |
|
probably null |
Het |
| Kif11 |
A |
T |
19: 37,379,095 (GRCm39) |
|
probably null |
Het |
| Lars1 |
A |
T |
18: 42,361,835 (GRCm39) |
W591R |
probably damaging |
Het |
| Lrtm1 |
T |
A |
14: 28,743,894 (GRCm39) |
S121T |
probably damaging |
Het |
| Med12l |
A |
C |
3: 59,169,389 (GRCm39) |
D1593A |
probably damaging |
Het |
| Med17 |
A |
T |
9: 15,188,928 (GRCm39) |
D112E |
possibly damaging |
Het |
| Mettl2 |
T |
A |
11: 105,019,866 (GRCm39) |
F168I |
probably benign |
Het |
| Mmp9 |
A |
T |
2: 164,792,365 (GRCm39) |
D323V |
probably damaging |
Het |
| Mpzl2 |
C |
T |
9: 44,961,006 (GRCm39) |
T214I |
probably benign |
Het |
| Ms4a15 |
T |
C |
19: 10,958,670 (GRCm39) |
H134R |
probably benign |
Het |
| Ms4a6d |
T |
A |
19: 11,580,653 (GRCm39) |
I2F |
probably damaging |
Het |
| Muc3a |
G |
A |
5: 137,244,535 (GRCm39) |
P206S |
unknown |
Het |
| Nectin2 |
C |
A |
7: 19,458,733 (GRCm39) |
L359F |
probably damaging |
Het |
| Or2y6 |
C |
A |
11: 52,104,096 (GRCm39) |
C240F |
probably damaging |
Het |
| Or4f53 |
T |
A |
2: 111,087,918 (GRCm39) |
F153I |
probably benign |
Het |
| Pgm2 |
G |
T |
5: 64,269,467 (GRCm39) |
C518F |
possibly damaging |
Het |
| Plppr4 |
A |
G |
3: 117,116,114 (GRCm39) |
V581A |
probably damaging |
Het |
| Prkra |
G |
C |
2: 76,469,634 (GRCm39) |
L142V |
probably damaging |
Het |
| Prpf38a |
G |
A |
4: 108,434,195 (GRCm39) |
T74I |
probably benign |
Het |
| Ptprs |
T |
A |
17: 56,736,064 (GRCm39) |
N635I |
probably damaging |
Het |
| Rxfp2 |
A |
G |
5: 149,987,201 (GRCm39) |
N361D |
probably benign |
Het |
| Ryr3 |
T |
G |
2: 112,608,588 (GRCm39) |
I2351L |
probably damaging |
Het |
| Sfmbt2 |
A |
T |
2: 10,580,190 (GRCm39) |
T618S |
probably benign |
Het |
| Six6 |
A |
G |
12: 72,986,906 (GRCm39) |
D26G |
probably damaging |
Het |
| Slc20a1 |
T |
C |
2: 129,051,047 (GRCm39) |
L568P |
probably damaging |
Het |
| Slx4ip |
T |
A |
2: 136,842,104 (GRCm39) |
C10S |
probably damaging |
Het |
| Sox13 |
G |
T |
1: 133,311,498 (GRCm39) |
T578K |
probably benign |
Het |
| Spire2 |
A |
T |
8: 124,088,042 (GRCm39) |
S509C |
probably damaging |
Het |
| Sptbn4 |
T |
C |
7: 27,074,808 (GRCm39) |
D1521G |
possibly damaging |
Het |
| Sult2a7 |
T |
C |
7: 14,204,098 (GRCm39) |
T207A |
probably benign |
Het |
| Sun2 |
A |
G |
15: 79,609,721 (GRCm39) |
I708T |
probably damaging |
Het |
| Supt5 |
T |
C |
7: 28,030,899 (GRCm39) |
E44G |
unknown |
Het |
| Thsd1 |
A |
G |
8: 22,733,022 (GRCm39) |
E23G |
probably damaging |
Het |
| Ticrr |
T |
C |
7: 79,310,728 (GRCm39) |
V214A |
possibly damaging |
Het |
| Vmn2r74 |
A |
T |
7: 85,605,324 (GRCm39) |
F441L |
probably damaging |
Het |
| Zfp30 |
A |
G |
7: 29,493,080 (GRCm39) |
T526A |
probably benign |
Het |
| Zfp518a |
G |
T |
19: 40,902,415 (GRCm39) |
Q781H |
probably damaging |
Het |
| Zmynd11 |
A |
G |
13: 9,739,687 (GRCm39) |
V434A |
probably benign |
Het |
| Zranb1 |
A |
G |
7: 132,585,508 (GRCm39) |
D652G |
probably damaging |
Het |
|
| Other mutations in Helz |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00971:Helz
|
APN |
11 |
107,554,479 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01419:Helz
|
APN |
11 |
107,577,340 (GRCm39) |
missense |
unknown |
|
|
IGL01864:Helz
|
APN |
11 |
107,493,180 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01999:Helz
|
APN |
11 |
107,493,754 (GRCm39) |
splice site |
probably benign |
|
|
IGL02938:Helz
|
APN |
11 |
107,577,264 (GRCm39) |
missense |
unknown |
|
|
IGL03157:Helz
|
APN |
11 |
107,468,714 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03374:Helz
|
APN |
11 |
107,510,973 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0112:Helz
|
UTSW |
11 |
107,563,774 (GRCm39) |
unclassified |
probably benign |
|
|
R0243:Helz
|
UTSW |
11 |
107,528,740 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0328:Helz
|
UTSW |
11 |
107,495,174 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0578:Helz
|
UTSW |
11 |
107,577,226 (GRCm39) |
missense |
unknown |
|
|
R0928:Helz
|
UTSW |
11 |
107,517,519 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1428:Helz
|
UTSW |
11 |
107,483,666 (GRCm39) |
splice site |
probably benign |
|
|
R1493:Helz
|
UTSW |
11 |
107,504,751 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1494:Helz
|
UTSW |
11 |
107,494,889 (GRCm39) |
splice site |
probably benign |
|
|
R1541:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1619:Helz
|
UTSW |
11 |
107,527,105 (GRCm39) |
nonsense |
probably null |
|
|
R1809:Helz
|
UTSW |
11 |
107,489,997 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1942:Helz
|
UTSW |
11 |
107,493,318 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2095:Helz
|
UTSW |
11 |
107,536,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2133:Helz
|
UTSW |
11 |
107,561,310 (GRCm39) |
missense |
unknown |
|
|
R2167:Helz
|
UTSW |
11 |
107,563,790 (GRCm39) |
unclassified |
probably benign |
|
|
R2406:Helz
|
UTSW |
11 |
107,577,378 (GRCm39) |
missense |
unknown |
|
|
R2571:Helz
|
UTSW |
11 |
107,504,778 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2858:Helz
|
UTSW |
11 |
107,563,753 (GRCm39) |
unclassified |
probably benign |
|
|
R3927:Helz
|
UTSW |
11 |
107,576,118 (GRCm39) |
missense |
unknown |
|
|
R4449:Helz
|
UTSW |
11 |
107,494,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4453:Helz
|
UTSW |
11 |
107,563,455 (GRCm39) |
nonsense |
probably null |
|
|
R4583:Helz
|
UTSW |
11 |
107,536,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4684:Helz
|
UTSW |
11 |
107,539,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4714:Helz
|
UTSW |
11 |
107,517,542 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4875:Helz
|
UTSW |
11 |
107,528,560 (GRCm39) |
intron |
probably benign |
|
|
R4924:Helz
|
UTSW |
11 |
107,493,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4930:Helz
|
UTSW |
11 |
107,510,994 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5078:Helz
|
UTSW |
11 |
107,546,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5446:Helz
|
UTSW |
11 |
107,523,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5535:Helz
|
UTSW |
11 |
107,536,946 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5650:Helz
|
UTSW |
11 |
107,485,972 (GRCm39) |
missense |
probably null |
0.96 |
|
R5714:Helz
|
UTSW |
11 |
107,517,347 (GRCm39) |
splice site |
probably null |
|
|
R5784:Helz
|
UTSW |
11 |
107,561,307 (GRCm39) |
missense |
unknown |
|
|
R5998:Helz
|
UTSW |
11 |
107,576,360 (GRCm39) |
nonsense |
probably null |
|
|
R6042:Helz
|
UTSW |
11 |
107,504,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6089:Helz
|
UTSW |
11 |
107,485,963 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6137:Helz
|
UTSW |
11 |
107,509,886 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6373:Helz
|
UTSW |
11 |
107,486,010 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6392:Helz
|
UTSW |
11 |
107,493,167 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6618:Helz
|
UTSW |
11 |
107,489,976 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6644:Helz
|
UTSW |
11 |
107,523,087 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6811:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6874:Helz
|
UTSW |
11 |
107,554,460 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6911:Helz
|
UTSW |
11 |
107,510,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7039:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7061:Helz
|
UTSW |
11 |
107,540,003 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7438:Helz
|
UTSW |
11 |
107,552,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7464:Helz
|
UTSW |
11 |
107,527,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7513:Helz
|
UTSW |
11 |
107,546,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7559:Helz
|
UTSW |
11 |
107,491,104 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7734:Helz
|
UTSW |
11 |
107,576,248 (GRCm39) |
missense |
unknown |
|
|
R7780:Helz
|
UTSW |
11 |
107,528,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7982:Helz
|
UTSW |
11 |
107,517,456 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8024:Helz
|
UTSW |
11 |
107,577,247 (GRCm39) |
missense |
unknown |
|
|
R8346:Helz
|
UTSW |
11 |
107,563,399 (GRCm39) |
missense |
unknown |
|
|
R8729:Helz
|
UTSW |
11 |
107,528,754 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8807:Helz
|
UTSW |
11 |
107,493,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8821:Helz
|
UTSW |
11 |
107,525,919 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8891:Helz
|
UTSW |
11 |
107,552,842 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8909:Helz
|
UTSW |
11 |
107,556,834 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8922:Helz
|
UTSW |
11 |
107,539,985 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8926:Helz
|
UTSW |
11 |
107,563,509 (GRCm39) |
missense |
unknown |
|
|
R8988:Helz
|
UTSW |
11 |
107,495,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9053:Helz
|
UTSW |
11 |
107,563,761 (GRCm39) |
missense |
unknown |
|
|
R9056:Helz
|
UTSW |
11 |
107,547,019 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9099:Helz
|
UTSW |
11 |
107,523,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9122:Helz
|
UTSW |
11 |
107,556,830 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9194:Helz
|
UTSW |
11 |
107,561,113 (GRCm39) |
nonsense |
probably null |
|
|
R9220:Helz
|
UTSW |
11 |
107,560,873 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9223:Helz
|
UTSW |
11 |
107,509,918 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9242:Helz
|
UTSW |
11 |
107,523,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9644:Helz
|
UTSW |
11 |
107,563,687 (GRCm39) |
missense |
unknown |
|
|
R9761:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
nonsense |
probably null |
|
|
X0065:Helz
|
UTSW |
11 |
107,561,273 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGTAACTCTTGGGTGCCAG -3'
(R):5'- GGTGTTCAGATGGCAACGAG -3'
Sequencing Primer
(F):5'- GCCAGTTTGGGATTAATTTATGCC -3'
(R):5'- AGCCAAATAGCTGAGGCG -3'
|
| Posted On |
2020-07-13 |
Incidental Mutation