Incidental Mutation 'R8190:Iqgap3'
| ID |
635058 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
067613-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.314)
|
| Stock # |
R8190 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 87998086 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Leucine
at position 281
(Q281L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071715
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000195465]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071812
AA Change: Q281L
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: Q281L
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000195465
AA Change: Q281L
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000142013
Gene: ENSMUSG00000028068
AA Change: Q281L
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
8.5e-17 |
SMART |
|
internal_repeat_1
|
209 |
379 |
1.33e-7 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
612 |
1.33e-7 |
PROSPERO |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.3%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actr8 |
T |
C |
14: 29,706,030 (GRCm39) |
V113A |
possibly damaging |
Het |
| Adcy7 |
A |
G |
8: 89,037,666 (GRCm39) |
M245V |
possibly damaging |
Het |
| Adgra1 |
G |
T |
7: 139,456,034 (GRCm39) |
R554L |
probably benign |
Het |
| Agfg2 |
T |
A |
5: 137,653,664 (GRCm39) |
M351L |
probably benign |
Het |
| Ahnak |
G |
A |
19: 8,979,619 (GRCm39) |
G301D |
probably benign |
Het |
| Ambra1 |
C |
T |
2: 91,602,697 (GRCm39) |
A227V |
possibly damaging |
Het |
| Ankrd24 |
T |
A |
10: 81,474,152 (GRCm39) |
D166E |
unknown |
Het |
| Anks1 |
C |
T |
17: 28,205,778 (GRCm39) |
P341S |
probably benign |
Het |
| Ano4 |
C |
T |
10: 88,808,607 (GRCm39) |
D766N |
probably benign |
Het |
| Apol7e |
A |
T |
15: 77,602,007 (GRCm39) |
T202S |
possibly damaging |
Het |
| Arhgap44 |
C |
A |
11: 64,929,479 (GRCm39) |
C275F |
probably damaging |
Het |
| Arl6ip4 |
A |
C |
5: 124,255,095 (GRCm39) |
K95T |
probably damaging |
Het |
| Bbs9 |
T |
C |
9: 22,590,284 (GRCm39) |
L674P |
probably damaging |
Het |
| Bmp4 |
T |
A |
14: 46,621,972 (GRCm39) |
M191L |
probably benign |
Het |
| Celsr1 |
A |
G |
15: 85,787,090 (GRCm39) |
L2753P |
probably damaging |
Het |
| Cerkl |
T |
A |
2: 79,163,901 (GRCm39) |
H473L |
probably benign |
Het |
| Cfap99 |
A |
T |
5: 34,482,502 (GRCm39) |
T538S |
possibly damaging |
Het |
| Clock |
A |
T |
5: 76,375,051 (GRCm39) |
V706E |
probably damaging |
Het |
| Cpne6 |
T |
C |
14: 55,749,485 (GRCm39) |
M15T |
probably benign |
Het |
| Deaf1 |
T |
C |
7: 140,894,324 (GRCm39) |
D351G |
probably damaging |
Het |
| Dnajb8 |
C |
T |
6: 88,199,940 (GRCm39) |
R159C |
possibly damaging |
Het |
| Eif3j1 |
A |
T |
2: 121,877,969 (GRCm39) |
D119V |
probably damaging |
Het |
| Eps8l1 |
C |
A |
7: 4,474,297 (GRCm39) |
S195Y |
probably benign |
Het |
| Exosc5 |
T |
C |
7: 25,365,769 (GRCm39) |
|
probably null |
Het |
| Fabp2 |
A |
T |
3: 122,690,419 (GRCm39) |
H34L |
probably benign |
Het |
| Fbln5 |
T |
A |
12: 101,723,555 (GRCm39) |
Q382L |
probably damaging |
Het |
| Fbxo34 |
C |
A |
14: 47,767,879 (GRCm39) |
T464K |
possibly damaging |
Het |
| Fndc8 |
T |
G |
11: 82,788,686 (GRCm39) |
V172G |
probably damaging |
Het |
| Frs2 |
C |
T |
10: 116,910,784 (GRCm39) |
V193I |
possibly damaging |
Het |
| Gadd45a |
A |
G |
6: 67,013,813 (GRCm39) |
I44T |
possibly damaging |
Het |
| Gprin3 |
A |
G |
6: 59,331,456 (GRCm39) |
S284P |
possibly damaging |
Het |
| Gsta4 |
T |
C |
9: 78,105,654 (GRCm39) |
V28A |
possibly damaging |
Het |
| Herc1 |
T |
A |
9: 66,325,733 (GRCm39) |
D1402E |
probably benign |
Het |
| Hipk2 |
A |
T |
6: 38,795,728 (GRCm39) |
S180R |
possibly damaging |
Het |
| Hrg |
A |
T |
16: 22,779,793 (GRCm39) |
H357L |
unknown |
Het |
| Htr4 |
A |
G |
18: 62,570,971 (GRCm39) |
Q342R |
possibly damaging |
Het |
| Impa1 |
A |
G |
3: 10,386,688 (GRCm39) |
S184P |
possibly damaging |
Het |
| Kcnh8 |
C |
T |
17: 53,263,936 (GRCm39) |
P811L |
probably damaging |
Het |
| Lpin1 |
T |
C |
12: 16,599,003 (GRCm39) |
I628V |
|
Het |
| Lrrc38 |
G |
A |
4: 143,077,303 (GRCm39) |
G189R |
probably damaging |
Het |
| Mfn1 |
A |
T |
3: 32,622,538 (GRCm39) |
I599F |
possibly damaging |
Het |
| Nalcn |
T |
A |
14: 123,837,351 (GRCm39) |
R4S |
possibly damaging |
Het |
| Nbeal2 |
C |
T |
9: 110,455,158 (GRCm39) |
R2580Q |
probably benign |
Het |
| Nlrp4b |
A |
G |
7: 10,448,319 (GRCm39) |
N174S |
probably damaging |
Het |
| Or3a4 |
T |
A |
11: 73,945,305 (GRCm39) |
R93S |
probably benign |
Het |
| Or4q3 |
A |
T |
14: 50,583,179 (GRCm39) |
V240D |
probably damaging |
Het |
| Or52a5 |
A |
T |
7: 103,426,802 (GRCm39) |
V250D |
probably damaging |
Het |
| Or5p63 |
A |
G |
7: 107,811,014 (GRCm39) |
F241L |
possibly damaging |
Het |
| Pabpc2 |
G |
A |
18: 39,908,520 (GRCm39) |
R595Q |
probably benign |
Het |
| Pak6 |
C |
T |
2: 118,520,578 (GRCm39) |
Q190* |
probably null |
Het |
| Pds5a |
A |
T |
5: 65,781,341 (GRCm39) |
H1046Q |
probably damaging |
Het |
| Plin1 |
A |
G |
7: 79,373,028 (GRCm39) |
S314P |
probably benign |
Het |
| Pramel20 |
T |
G |
4: 143,298,530 (GRCm39) |
Y158D |
probably benign |
Het |
| Ptpra |
G |
A |
2: 30,328,351 (GRCm39) |
S224N |
probably damaging |
Het |
| Rbp1 |
T |
G |
9: 98,326,709 (GRCm39) |
W107G |
probably damaging |
Het |
| Rgs7bp |
T |
C |
13: 105,189,617 (GRCm39) |
N61D |
probably damaging |
Het |
| Slc1a6 |
A |
G |
10: 78,627,067 (GRCm39) |
T135A |
probably damaging |
Het |
| Smarcc1 |
T |
A |
9: 110,031,602 (GRCm39) |
D783E |
probably benign |
Het |
| Sufu |
G |
T |
19: 46,389,636 (GRCm39) |
E86* |
probably null |
Het |
| Synm |
A |
T |
7: 67,383,654 (GRCm39) |
M1336K |
probably benign |
Het |
| Tgm1 |
C |
T |
14: 55,942,341 (GRCm39) |
G670D |
probably damaging |
Het |
| Tmc8 |
T |
G |
11: 117,682,186 (GRCm39) |
|
probably null |
Het |
| Togaram1 |
T |
C |
12: 65,053,686 (GRCm39) |
V1322A |
probably damaging |
Het |
| Uxs1 |
A |
T |
1: 43,810,911 (GRCm39) |
I225K |
possibly damaging |
Het |
| Vil1 |
G |
T |
1: 74,474,052 (GRCm39) |
E796* |
probably null |
Het |
| Vmn1r174 |
T |
C |
7: 23,453,568 (GRCm39) |
F78S |
probably damaging |
Het |
| Vps13d |
T |
A |
4: 144,879,321 (GRCm39) |
I1501F |
|
Het |
| Vps8 |
A |
T |
16: 21,393,780 (GRCm39) |
T1216S |
possibly damaging |
Het |
| Yipf4 |
G |
T |
17: 74,800,967 (GRCm39) |
R95L |
probably damaging |
Het |
| Zan |
T |
A |
5: 137,465,346 (GRCm39) |
T470S |
probably damaging |
Het |
| Zfp113 |
G |
T |
5: 138,143,258 (GRCm39) |
H331N |
probably damaging |
Het |
| Zfp62 |
A |
G |
11: 49,106,902 (GRCm39) |
Y331C |
probably damaging |
Het |
| Zfyve26 |
T |
C |
12: 79,327,610 (GRCm39) |
H580R |
probably benign |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCGACTGGCTTAATTGTTGG -3'
(R):5'- CTCTGGTAAGAACCTCTCTGC -3'
Sequencing Primer
(F):5'- TCCTCAGCAGGCTGGTCTTG -3'
(R):5'- TCTCTGCTGAGGCCAGAGAG -3'
|
| Posted On |
2020-07-13 |
Incidental Mutation