Incidental Mutation 'R8214:Vmn1r16'
ID636304
Institutional Source Beutler Lab
Gene Symbol Vmn1r16
Ensembl Gene ENSMUSG00000115792
Gene Namevomeronasal 1 receptor 16
SynonymsV1rc29
MMRRC Submission
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.123) question?
Stock #R8214 (G1)
Quality Score225.009
Status Validated
Chromosome6
Chromosomal Location57318052-57329494 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 57323439 bp
ZygosityHeterozygous
Amino Acid Change Glutamic Acid to Glycine at position 66 (E66G)
Ref Sequence ENSEMBL: ENSMUSP00000134873 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000177267]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000177267
AA Change: E66G
SMART Domains Protein: ENSMUSP00000134873
Gene: ENSMUSG00000093523
AA Change: E66G

DomainStartEndE-ValueType
Pfam:V1R 28 293 3.4e-57 PFAM
Meta Mutation Damage Score 0.0852 question?
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 99.9%
  • 10x: 99.7%
  • 20x: 99.1%
Validation Efficiency 100% (42/42)
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930438A08Rik G A 11: 58,286,621 R52Q Het
Abcc3 C T 11: 94,363,518 R718H probably damaging Het
Abcc4 T C 14: 118,500,841 M1166V probably benign Het
Abhd16b C T 2: 181,494,190 T295I probably damaging Het
Amph A G 13: 19,104,298 N319S possibly damaging Het
Ankrd27 A G 7: 35,614,519 D425G probably damaging Het
Atg4b T C 1: 93,784,887 S316P probably damaging Het
Brd4 A G 17: 32,212,947 S649P probably benign Het
Bzw1 T C 1: 58,405,037 S411P probably damaging Het
Dnah6 T C 6: 73,044,728 D3537G probably damaging Het
Dnpep A T 1: 75,315,998 W126R probably damaging Het
Efcab2 T C 1: 178,437,450 V27A probably benign Het
Kctd21 T C 7: 97,347,341 L7P probably damaging Het
Kidins220 C T 12: 24,994,855 T216I probably damaging Het
Lpl T A 8: 68,892,605 M87K probably damaging Het
Lrrc16a T C 13: 24,044,232 E987G probably damaging Het
Ltn1 A G 16: 87,380,803 V1646A probably benign Het
Madcam1 A G 10: 79,666,758 T359A probably benign Het
Muc5ac A G 7: 141,802,948 K1092E possibly damaging Het
Nrg2 T C 18: 36,196,676 E162G probably benign Het
Olfr1333 A T 4: 118,830,091 F117L probably benign Het
Olfr474 T A 7: 107,954,967 S109T probably benign Het
Olfr589 A C 7: 103,155,406 S114A probably damaging Het
Pcdhb5 G T 18: 37,321,583 V339L probably benign Het
Plec A G 15: 76,192,284 W145R unknown Het
Polr3f A G 2: 144,536,310 N201D probably benign Het
Skint5 T C 4: 113,804,942 probably null Het
Slc12a2 A G 18: 57,937,719 I1048V probably benign Het
Sult2a4 A G 7: 13,989,476 I39T probably benign Het
Tenm4 T C 7: 96,895,407 V2247A probably damaging Het
Tg C T 15: 66,773,398 R2385C probably damaging Het
Tomm70a G T 16: 57,121,967 A36S unknown Het
Top2b G A 14: 16,383,177 R55H probably damaging Het
Unc45b A G 11: 82,933,888 I629M possibly damaging Het
Vmn1r189 C T 13: 22,102,131 V179I probably benign Het
Vmn2r105 T G 17: 20,228,513 E134A probably benign Het
Wdr70 G A 15: 7,887,370 A522V probably benign Het
Zcchc11 A G 4: 108,512,150 I636V probably benign Het
Zfp184 T A 13: 21,958,825 C234S probably damaging Het
Zscan5b C T 7: 6,233,947 P232S possibly damaging Het
Other mutations in Vmn1r16
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01350:Vmn1r16 APN 6 57322731 missense possibly damaging 0.74
IGL02027:Vmn1r16 APN 6 57323059 missense possibly damaging 0.49
IGL02804:Vmn1r16 APN 6 57323482 missense probably benign 0.18
IGL03329:Vmn1r16 APN 6 57323618 missense probably damaging 0.99
IGL03392:Vmn1r16 APN 6 57322894 missense probably damaging 1.00
I1329:Vmn1r16 UTSW 6 57323534 missense probably damaging 0.97
PIT4581001:Vmn1r16 UTSW 6 57322873 missense probably benign 0.12
R0750:Vmn1r16 UTSW 6 57322827 missense probably benign 0.00
R1137:Vmn1r16 UTSW 6 57323236 missense probably damaging 1.00
R1239:Vmn1r16 UTSW 6 57323633 start codon destroyed probably null 1.00
R1796:Vmn1r16 UTSW 6 57323271 missense probably benign 0.03
R1858:Vmn1r16 UTSW 6 57322899 missense probably damaging 1.00
R1895:Vmn1r16 UTSW 6 57322900 missense probably benign 0.31
R1946:Vmn1r16 UTSW 6 57322900 missense probably benign 0.31
R3832:Vmn1r16 UTSW 6 57323227 missense probably benign 0.00
R4801:Vmn1r16 UTSW 6 57323190 missense probably benign 0.03
R4802:Vmn1r16 UTSW 6 57323190 missense probably benign 0.03
R6658:Vmn1r16 UTSW 6 57323106 nonsense probably null
R6981:Vmn1r16 UTSW 6 57323488 missense probably benign 0.30
R6991:Vmn1r16 UTSW 6 57322884 nonsense probably null
R7915:Vmn1r16 UTSW 6 57323395 missense probably damaging 1.00
R8459:Vmn1r16 UTSW 6 57323362 missense probably benign 0.12
R8531:Vmn1r16 UTSW 6 57322915 missense probably damaging 1.00
R8676:Vmn1r16 UTSW 6 57322829 missense probably benign 0.01
X0061:Vmn1r16 UTSW 6 57323364 missense probably damaging 1.00
Predicted Primers PCR Primer
(F):5'- GCAGGATTTAGTGACCTTCATCTG -3'
(R):5'- TCCAAGCTGGATTTGGACTC -3'

Sequencing Primer
(F):5'- GGTTTTCACTCACATTGGTAAAACC -3'
(R):5'- CCAAGCTGGATTTGGACTCTTAGC -3'
Posted On2020-07-13