Mutagenetix > Incidental Mutation

Incidental Mutation 'R0718:Ush2a'

63668

Institutional Source

Beutler Lab

Gene Symbol

Ush2a

Ensembl Gene

ENSMUSG00000026609

Gene Name

usherin

Synonyms

A930011D15Rik, LOC381317, A930037M10Rik, LOC269160, Usherin, MUSH2A

MMRRC Submission

038900-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.699) question?

Stock #

R0718 (G1)

Quality Score

103

Status

Validated

Chromosome

Chromosomal Location

188262023-188965041 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 188797830 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Tyrosine at position 3272 (C3272Y)

Ref Sequence

ENSEMBL: ENSMUSP00000050454 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000060479]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000060479
AA Change: C3272Y

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000050454
Gene: ENSMUSG00000026609
AA Change: C3272Y

Domain	Start	End	E-Value	Type
transmembrane domain	9	31	N/A	INTRINSIC
Pfam:Laminin_G_3	128	283	6.5e-16	PFAM
LamNT	310	513	6.79e-9	SMART
EGF_Lam	515	569	1.58e-3	SMART
EGF_Lam	572	635	5.69e-10	SMART
EGF_Lam	638	688	4.38e-11	SMART
EGF_Lam	691	741	3.56e-11	SMART
EGF_Lam	744	789	7.93e-9	SMART
EGF_Lam	792	841	3.37e-12	SMART
EGF_Lam	844	894	2.01e-10	SMART
EGF_Lam	897	945	5.43e-16	SMART
EGF_Lam	948	996	7.88e-4	SMART
EGF_Lam	999	1047	2.96e-8	SMART
FN3	1051	1130	1e-1	SMART
FN3	1145	1224	2.06e-3	SMART
FN3	1239	1342	8.69e-11	SMART
FN3	1356	1447	5.32e-6	SMART
FN3	1461	1570	2.63e1	SMART
LamG	1531	1672	5.39e-19	SMART
LamG	1727	1862	2.33e-23	SMART
FN3	1861	1931	9.15e1	SMART
FN3	1945	2032	2.24e-4	SMART
FN3	2047	2120	1.13e0	SMART
FN3	2134	2218	3.4e-4	SMART
FN3	2232	2306	1.59e-4	SMART
FN3	2320	2412	1.12e-4	SMART
FN3	2423	2510	8.9e-8	SMART
FN3	2524	2600	1.95e-4	SMART
FN3	2612	2701	4.67e-2	SMART
FN3	2715	2792	1.17e-7	SMART
FN3	2809	2902	1.12e-4	SMART
FN3	2913	2997	5.36e-2	SMART
FN3	3011	3089	2.46e-1	SMART
FN3	3101	3477	2.85e1	SMART
FN3	3491	3568	4e-1	SMART
FN3	3582	3659	5.87e-8	SMART
FN3	3673	3750	1.75e-6	SMART
FN3	3764	3845	9.62e-4	SMART
FN3	3859	3943	2.41e-4	SMART
FN3	3954	4044	5.11e-8	SMART
FN3	4058	4133	1.06e0	SMART
FN3	4147	4241	7.87e-9	SMART
FN3	4255	4334	1.15e-1	SMART
FN3	4348	4422	6.39e-9	SMART
FN3	4435	4510	6.91e-5	SMART
FN3	4521	4610	2.28e-5	SMART
FN3	4626	4713	1.71e0	SMART
FN3	4724	4805	1.3e0	SMART
FN3	4817	4909	3.62e-8	SMART
transmembrane domain	5032	5054	N/A	INTRINSIC

Meta Mutation Damage Score

0.6546

Coding Region Coverage

1x: 99.3%
3x: 98.8%
10x: 97.6%
20x: 95.9%

Validation Efficiency

100% (96/96)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
PHENOTYPE: Mice homozygous for a knock-out allele display progressive retinal photoreceptor degeneration along with significantly reduced a- and b-wave amplitudes, and a moderate but nonprogressive high-frequency hearing loss associated with widespread loss of outer hair cells in the basal turn of the cochlea. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 93 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamtsl4	A	T	3: 95,679,608 (GRCm38)	Y811N	possibly damaging	Het
Adrm1	T	C	2: 180,175,147 (GRCm38)		probably benign	Het
Alms1	T	A	6: 85,621,821 (GRCm38)	S1210T	probably benign	Het
Ampd3	C	T	7: 110,777,808 (GRCm38)	P11L	probably damaging	Het
Arhgap5	A	G	12: 52,516,507 (GRCm38)	E87G	possibly damaging	Het
Armc5	C	T	7: 128,240,070 (GRCm38)		probably benign	Het
Asic2	C	G	11: 80,971,456 (GRCm38)		probably benign	Het
Asph	A	G	4: 9,514,683 (GRCm38)		probably benign	Het
Bicd2	T	A	13: 49,377,875 (GRCm38)		probably null	Het
Brip1	A	G	11: 86,143,305 (GRCm38)	L530P	possibly damaging	Het
Bsn	G	T	9: 108,111,360 (GRCm38)		probably benign	Het
Btnl4	T	A	17: 34,469,634 (GRCm38)	H390L	probably benign	Het
Ccdc70	A	C	8: 21,973,308 (GRCm38)	K38T	probably damaging	Het
Ccni	G	A	5: 93,202,316 (GRCm38)	P35S	probably benign	Het
Cdh17	A	G	4: 11,810,451 (GRCm38)	D714G	possibly damaging	Het
Cenpf	A	G	1: 189,653,984 (GRCm38)	L2033P	probably damaging	Het
Cfap69	A	T	5: 5,621,924 (GRCm38)	M328K	probably damaging	Het
Cmah	T	G	13: 24,417,210 (GRCm38)		probably null	Het
Cog6	T	C	3: 53,010,629 (GRCm38)	T163A	probably benign	Het
Cyp2j8	G	A	4: 96,501,196 (GRCm38)	S130F	probably benign	Het
Dgki	A	G	6: 37,012,896 (GRCm38)	V636A	probably damaging	Het
Dmkn	T	A	7: 30,764,786 (GRCm38)		probably benign	Het
Dnah6	A	G	6: 73,035,293 (GRCm38)	I3679T	possibly damaging	Het
Dsp	A	T	13: 38,196,764 (GRCm38)	Y2495F	possibly damaging	Het
Exosc4	C	T	15: 76,329,489 (GRCm38)	A171V	probably benign	Het
Fbxw24	A	G	9: 109,623,509 (GRCm38)		probably benign	Het
Flvcr1	A	T	1: 191,025,582 (GRCm38)	L171Q	probably damaging	Het
Fsd1	G	T	17: 55,996,445 (GRCm38)		probably null	Het
Gm7732	A	G	17: 21,129,844 (GRCm38)		noncoding transcript	Het
H2-K2	A	C	17: 33,975,623 (GRCm38)		noncoding transcript	Het
Hgf	A	G	5: 16,593,859 (GRCm38)	N295S	probably damaging	Het
Ift88	T	A	14: 57,517,413 (GRCm38)	D811E	probably benign	Het
Igsf9b	T	A	9: 27,323,361 (GRCm38)		probably null	Het
Immt	T	A	6: 71,863,172 (GRCm38)	V311E	probably damaging	Het
Ipo11	T	A	13: 106,919,611 (GRCm38)	N51I	possibly damaging	Het
Isy1	T	C	6: 87,819,176 (GRCm38)	K260E	probably damaging	Het
Jchain	T	G	5: 88,526,202 (GRCm38)	I28L	probably benign	Het
Jmjd1c	T	A	10: 67,218,946 (GRCm38)		probably null	Het
Kif13b	T	C	14: 64,751,662 (GRCm38)		probably benign	Het
Klhdc7b	T	C	15: 89,388,169 (GRCm38)	Y427H	possibly damaging	Het
Klhl8	T	C	5: 103,876,293 (GRCm38)		probably benign	Het
Lrp2	C	T	2: 69,510,948 (GRCm38)	D963N	probably damaging	Het
Ltbp3	G	T	19: 5,746,748 (GRCm38)		probably benign	Het
Ltf	C	A	9: 111,040,379 (GRCm38)	Q41K	probably benign	Het
Med4	T	A	14: 73,516,657 (GRCm38)	I148N	probably damaging	Het
Mlh3	T	G	12: 85,247,697 (GRCm38)	S1242R	possibly damaging	Het
Mllt6	T	C	11: 97,676,359 (GRCm38)		probably benign	Het
Mpdz	A	G	4: 81,292,473 (GRCm38)	I1712T	possibly damaging	Het
Mrgprb4	T	A	7: 48,198,553 (GRCm38)	H209L	probably benign	Het
Nkapl	A	T	13: 21,468,440 (GRCm38)	M1K	probably null	Het
Nmur2	T	A	11: 56,029,498 (GRCm38)		probably benign	Het
Nsun2	T	A	13: 69,543,697 (GRCm38)		probably benign	Het
Or10ag60	A	G	2: 87,607,927 (GRCm38)	I180V	probably benign	Het
Or8k35	G	A	2: 86,594,081 (GRCm38)	T249I	probably benign	Het
Ovgp1	T	C	3: 105,974,830 (GRCm38)		probably benign	Het
Pcdh8	A	G	14: 79,770,691 (GRCm38)	V144A	possibly damaging	Het
Pcnx3	G	A	19: 5,677,728 (GRCm38)		probably benign	Het
Pla2r1	C	A	2: 60,479,530 (GRCm38)	V570L	possibly damaging	Het
Plxnd1	C	A	6: 115,966,638 (GRCm38)	E1202D	possibly damaging	Het
Ppp1r37	T	C	7: 19,532,254 (GRCm38)	E529G	probably benign	Het
Prdm15	A	G	16: 97,812,633 (GRCm38)	F496L	possibly damaging	Het
Prlhr	A	T	19: 60,468,005 (GRCm38)	V41D	probably benign	Het
Prlhr	G	T	19: 60,468,059 (GRCm38)	S23*	probably null	Het
Prpf4	C	T	4: 62,414,540 (GRCm38)		probably benign	Het
Psg26	T	C	7: 18,478,287 (GRCm38)	H381R	probably benign	Het
Psg26	C	T	7: 18,475,235 (GRCm38)	R416H	probably benign	Het
Ralgds	T	G	2: 28,549,116 (GRCm38)	M717R	probably benign	Het
Rbms1	T	C	2: 60,842,412 (GRCm38)	N44D	probably damaging	Het
Rpa1	T	C	11: 75,318,401 (GRCm38)		probably benign	Het
Rprd2	T	C	3: 95,766,387 (GRCm38)	N568S	probably benign	Het
Rptor	A	G	11: 119,872,376 (GRCm38)	M929V	probably benign	Het
Rspo1	T	A	4: 125,007,149 (GRCm38)	C97S	possibly damaging	Het
Scin	C	T	12: 40,079,607 (GRCm38)	G396S	probably damaging	Het
Scn9a	T	C	2: 66,547,112 (GRCm38)	N409D	probably damaging	Het
Sf3b1	A	G	1: 55,019,385 (GRCm38)	I15T	probably damaging	Het
Sh3bp2	T	C	5: 34,555,495 (GRCm38)	V149A	probably damaging	Het
Slc39a12	T	A	2: 14,407,426 (GRCm38)		probably benign	Het
Sp9	G	T	2: 73,273,827 (GRCm38)	A242S	possibly damaging	Het
Srr	A	G	11: 74,911,065 (GRCm38)	V126A	possibly damaging	Het
Tatdn3	G	T	1: 191,052,849 (GRCm38)		probably benign	Het
Tex14	G	A	11: 87,499,613 (GRCm38)	V379I	probably benign	Het
Tmed6	T	C	8: 107,061,724 (GRCm38)	N197S	probably damaging	Het
Ttbk2	G	A	2: 120,748,575 (GRCm38)	L689F	probably benign	Het
Ttbk2	A	T	2: 120,745,160 (GRCm38)	I1043N	probably benign	Het
Ttn	A	G	2: 76,810,696 (GRCm38)	S5283P	probably damaging	Het
Ube3b	C	A	5: 114,402,555 (GRCm38)	S441*	probably null	Het
Vac14	T	A	8: 110,632,477 (GRCm38)	I95K	probably damaging	Het
Vangl2	G	A	1: 172,006,217 (GRCm38)	A433V	probably damaging	Het
Vwa5b1	A	T	4: 138,608,824 (GRCm38)	V153D	probably damaging	Het
Zfhx3	T	A	8: 108,955,650 (GRCm38)	D3240E	unknown	Het
Zfp945	A	G	17: 22,851,030 (GRCm38)	C632R	probably damaging	Het
Zfyve26	G	A	12: 79,265,802 (GRCm38)		probably benign	Het
Zyg11b	A	T	4: 108,242,076 (GRCm38)	I606N	possibly damaging	Het

Other mutations in Ush2a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00155:Ush2a	APN	1	188,864,678 (GRCm38)	missense	probably benign	0.00
IGL00391:Ush2a	APN	1	188,916,061 (GRCm38)	missense	probably damaging	1.00
IGL00429:Ush2a	APN	1	188,400,114 (GRCm38)	nonsense	probably null
IGL00484:Ush2a	APN	1	188,782,513 (GRCm38)	missense	probably benign	0.00
IGL00519:Ush2a	APN	1	188,444,668 (GRCm38)	missense	probably benign	0.03
IGL00567:Ush2a	APN	1	188,964,917 (GRCm38)	missense	probably damaging	1.00
IGL00823:Ush2a	APN	1	188,911,443 (GRCm38)	missense	possibly damaging	0.61
IGL00940:Ush2a	APN	1	188,357,961 (GRCm38)	nonsense	probably null
IGL00951:Ush2a	APN	1	188,263,465 (GRCm38)	missense	probably benign	0.33
IGL00956:Ush2a	APN	1	188,753,522 (GRCm38)	missense	probably damaging	0.99
IGL01096:Ush2a	APN	1	188,678,377 (GRCm38)	missense	probably damaging	1.00
IGL01108:Ush2a	APN	1	188,862,825 (GRCm38)	missense	probably benign	0.00
IGL01315:Ush2a	APN	1	188,633,614 (GRCm38)	missense	possibly damaging	0.51
IGL01318:Ush2a	APN	1	188,814,353 (GRCm38)	missense	probably benign	0.00
IGL01324:Ush2a	APN	1	188,848,992 (GRCm38)	missense	probably benign	0.38
IGL01326:Ush2a	APN	1	188,263,321 (GRCm38)	nonsense	probably null
IGL01384:Ush2a	APN	1	188,553,228 (GRCm38)	missense	possibly damaging	0.65
IGL01466:Ush2a	APN	1	188,911,622 (GRCm38)	missense	probably benign	0.00
IGL01518:Ush2a	APN	1	188,399,785 (GRCm38)	missense	probably benign	0.01
IGL01585:Ush2a	APN	1	188,430,727 (GRCm38)	missense	probably damaging	1.00
IGL01595:Ush2a	APN	1	188,654,724 (GRCm38)	critical splice donor site	probably null
IGL01657:Ush2a	APN	1	188,826,461 (GRCm38)	missense	probably benign	0.03
IGL01797:Ush2a	APN	1	188,263,509 (GRCm38)	missense	probably damaging	1.00
IGL01802:Ush2a	APN	1	188,436,957 (GRCm38)	missense	probably damaging	0.99
IGL01836:Ush2a	APN	1	188,759,863 (GRCm38)	splice site	probably benign
IGL01938:Ush2a	APN	1	188,797,845 (GRCm38)	missense	probably damaging	1.00
IGL01976:Ush2a	APN	1	188,911,241 (GRCm38)	missense	probably benign	0.04
IGL02023:Ush2a	APN	1	188,733,514 (GRCm38)	missense	probably benign	0.03
IGL02126:Ush2a	APN	1	188,263,391 (GRCm38)	missense	probably benign	0.01
IGL02133:Ush2a	APN	1	188,443,343 (GRCm38)	missense	probably damaging	1.00
IGL02147:Ush2a	APN	1	188,864,703 (GRCm38)	missense	probably benign
IGL02275:Ush2a	APN	1	188,263,269 (GRCm38)	missense	possibly damaging	0.67
IGL02314:Ush2a	APN	1	188,633,629 (GRCm38)	missense	probably benign	0.00
IGL02353:Ush2a	APN	1	188,728,438 (GRCm38)	missense	probably benign	0.04
IGL02360:Ush2a	APN	1	188,728,438 (GRCm38)	missense	probably benign	0.04
IGL02367:Ush2a	APN	1	188,784,746 (GRCm38)	missense	probably benign
IGL02402:Ush2a	APN	1	188,267,108 (GRCm38)	missense	probably benign	0.02
IGL02410:Ush2a	APN	1	188,915,997 (GRCm38)	missense	probably damaging	1.00
IGL02490:Ush2a	APN	1	188,810,364 (GRCm38)	missense	probably damaging	1.00
IGL02500:Ush2a	APN	1	188,822,696 (GRCm38)	missense	probably damaging	1.00
IGL02511:Ush2a	APN	1	188,743,687 (GRCm38)	critical splice donor site	probably null
IGL02517:Ush2a	APN	1	188,915,998 (GRCm38)	missense	probably damaging	1.00
IGL02536:Ush2a	APN	1	188,957,266 (GRCm38)	critical splice acceptor site	probably null
IGL02585:Ush2a	APN	1	188,728,333 (GRCm38)	missense	probably benign	0.00
IGL02610:Ush2a	APN	1	188,444,466 (GRCm38)	missense	probably damaging	0.98
IGL02677:Ush2a	APN	1	188,734,685 (GRCm38)	missense	probably damaging	1.00
IGL02691:Ush2a	APN	1	188,734,752 (GRCm38)	missense	probably damaging	1.00
IGL02740:Ush2a	APN	1	188,648,388 (GRCm38)	missense	possibly damaging	0.68
IGL02744:Ush2a	APN	1	188,358,717 (GRCm38)	splice site	probably null
IGL02749:Ush2a	APN	1	188,946,958 (GRCm38)	missense	probably damaging	0.99
IGL02806:Ush2a	APN	1	188,810,357 (GRCm38)	nonsense	probably null
IGL02870:Ush2a	APN	1	188,678,358 (GRCm38)	missense	probably benign	0.42
IGL02894:Ush2a	APN	1	188,451,846 (GRCm38)	missense	probably damaging	1.00
IGL02904:Ush2a	APN	1	188,906,506 (GRCm38)	missense	probably benign	0.06
IGL03000:Ush2a	APN	1	188,549,856 (GRCm38)	missense	possibly damaging	0.81
IGL03015:Ush2a	APN	1	188,436,950 (GRCm38)	missense	probably benign	0.01
IGL03036:Ush2a	APN	1	188,864,621 (GRCm38)	missense	possibly damaging	0.80
IGL03057:Ush2a	APN	1	188,797,838 (GRCm38)	missense	probably damaging	1.00
IGL03230:Ush2a	APN	1	188,466,193 (GRCm38)	missense	probably benign	0.09
IGL03278:Ush2a	APN	1	188,849,116 (GRCm38)	missense	probably damaging	1.00
BB003:Ush2a	UTSW	1	188,728,600 (GRCm38)	missense	probably benign
BB013:Ush2a	UTSW	1	188,728,600 (GRCm38)	missense	probably benign
PIT4283001:Ush2a	UTSW	1	188,436,867 (GRCm38)	missense	probably benign	0.01
R0003:Ush2a	UTSW	1	188,578,491 (GRCm38)	missense	probably damaging	0.99
R0030:Ush2a	UTSW	1	188,822,657 (GRCm38)	missense	possibly damaging	0.51
R0035:Ush2a	UTSW	1	188,356,888 (GRCm38)	missense	probably benign
R0038:Ush2a	UTSW	1	188,626,612 (GRCm38)	missense	probably benign	0.00
R0038:Ush2a	UTSW	1	188,626,612 (GRCm38)	missense	probably benign	0.00
R0067:Ush2a	UTSW	1	188,964,846 (GRCm38)	missense	probably damaging	0.99
R0067:Ush2a	UTSW	1	188,964,846 (GRCm38)	missense	probably damaging	0.99
R0103:Ush2a	UTSW	1	188,319,070 (GRCm38)	missense	possibly damaging	0.81
R0103:Ush2a	UTSW	1	188,319,070 (GRCm38)	missense	possibly damaging	0.81
R0122:Ush2a	UTSW	1	188,948,455 (GRCm38)	missense	possibly damaging	0.65
R0206:Ush2a	UTSW	1	188,531,761 (GRCm38)	missense	probably damaging	0.99
R0208:Ush2a	UTSW	1	188,531,761 (GRCm38)	missense	probably damaging	0.99
R0230:Ush2a	UTSW	1	188,850,104 (GRCm38)	missense	probably damaging	1.00
R0269:Ush2a	UTSW	1	188,810,176 (GRCm38)	missense	probably benign	0.33
R0319:Ush2a	UTSW	1	188,948,374 (GRCm38)	splice site	probably benign
R0358:Ush2a	UTSW	1	188,537,780 (GRCm38)	missense	possibly damaging	0.83
R0379:Ush2a	UTSW	1	188,451,819 (GRCm38)	missense	probably damaging	1.00
R0427:Ush2a	UTSW	1	188,400,281 (GRCm38)	missense	probably damaging	1.00
R0437:Ush2a	UTSW	1	188,911,031 (GRCm38)	missense	probably benign	0.00
R0462:Ush2a	UTSW	1	188,910,939 (GRCm38)	missense	probably benign
R0510:Ush2a	UTSW	1	188,734,663 (GRCm38)	splice site	probably benign
R0531:Ush2a	UTSW	1	188,443,181 (GRCm38)	missense	probably benign	0.18
R0541:Ush2a	UTSW	1	188,714,466 (GRCm38)	splice site	probably benign
R0549:Ush2a	UTSW	1	188,946,953 (GRCm38)	missense	probably damaging	0.99
R0562:Ush2a	UTSW	1	188,356,847 (GRCm38)	missense	probably damaging	1.00
R0636:Ush2a	UTSW	1	188,822,738 (GRCm38)	missense	probably benign
R0662:Ush2a	UTSW	1	188,351,093 (GRCm38)	missense	probably benign	0.26
R0685:Ush2a	UTSW	1	188,400,278 (GRCm38)	missense	probably damaging	1.00
R0725:Ush2a	UTSW	1	188,951,525 (GRCm38)	missense	probably damaging	1.00
R0735:Ush2a	UTSW	1	188,864,693 (GRCm38)	missense	probably benign	0.04
R0744:Ush2a	UTSW	1	188,814,406 (GRCm38)	splice site	probably benign
R0765:Ush2a	UTSW	1	188,948,574 (GRCm38)	missense	possibly damaging	0.67
R0862:Ush2a	UTSW	1	188,542,818 (GRCm38)	nonsense	probably null
R1067:Ush2a	UTSW	1	188,550,207 (GRCm38)	missense	probably benign	0.35
R1072:Ush2a	UTSW	1	188,728,717 (GRCm38)	missense	possibly damaging	0.91
R1099:Ush2a	UTSW	1	188,864,639 (GRCm38)	missense	probably damaging	1.00
R1099:Ush2a	UTSW	1	188,648,348 (GRCm38)	missense	probably benign	0.06
R1104:Ush2a	UTSW	1	188,916,256 (GRCm38)	missense	probably benign
R1106:Ush2a	UTSW	1	188,910,983 (GRCm38)	missense	possibly damaging	0.82
R1124:Ush2a	UTSW	1	188,753,536 (GRCm38)	missense	probably damaging	0.99
R1168:Ush2a	UTSW	1	188,678,411 (GRCm38)	missense	probably benign	0.01
R1199:Ush2a	UTSW	1	188,759,795 (GRCm38)	missense	probably benign	0.00
R1215:Ush2a	UTSW	1	188,957,282 (GRCm38)	missense	possibly damaging	0.66
R1307:Ush2a	UTSW	1	188,451,840 (GRCm38)	missense	probably damaging	1.00
R1307:Ush2a	UTSW	1	188,357,967 (GRCm38)	missense	probably damaging	1.00
R1311:Ush2a	UTSW	1	188,947,145 (GRCm38)	missense	possibly damaging	0.86
R1388:Ush2a	UTSW	1	188,523,318 (GRCm38)	splice site	probably benign
R1416:Ush2a	UTSW	1	188,436,883 (GRCm38)	missense	probably damaging	1.00
R1424:Ush2a	UTSW	1	188,542,878 (GRCm38)	critical splice donor site	probably null
R1459:Ush2a	UTSW	1	188,862,851 (GRCm38)	missense	probably benign	0.05
R1470:Ush2a	UTSW	1	188,400,206 (GRCm38)	missense	probably benign	0.00
R1470:Ush2a	UTSW	1	188,400,206 (GRCm38)	missense	probably benign	0.00
R1477:Ush2a	UTSW	1	188,849,076 (GRCm38)	missense	probably benign	0.05
R1484:Ush2a	UTSW	1	188,810,337 (GRCm38)	nonsense	probably null
R1490:Ush2a	UTSW	1	188,359,841 (GRCm38)	missense	probably benign	0.24
R1510:Ush2a	UTSW	1	188,648,304 (GRCm38)	missense	probably damaging	1.00
R1522:Ush2a	UTSW	1	188,797,814 (GRCm38)	missense	possibly damaging	0.94
R1606:Ush2a	UTSW	1	188,759,766 (GRCm38)	missense	probably benign	0.17
R1618:Ush2a	UTSW	1	188,814,224 (GRCm38)	missense	probably benign	0.29
R1636:Ush2a	UTSW	1	188,466,176 (GRCm38)	missense	possibly damaging	0.53
R1646:Ush2a	UTSW	1	188,415,821 (GRCm38)	missense	probably damaging	1.00
R1660:Ush2a	UTSW	1	188,916,064 (GRCm38)	missense	probably benign
R1676:Ush2a	UTSW	1	188,728,585 (GRCm38)	missense	probably damaging	1.00
R1704:Ush2a	UTSW	1	188,821,796 (GRCm38)	missense	probably damaging	1.00
R1705:Ush2a	UTSW	1	188,911,541 (GRCm38)	missense	probably benign	0.40
R1705:Ush2a	UTSW	1	188,874,869 (GRCm38)	missense	probably damaging	1.00
R1760:Ush2a	UTSW	1	188,910,983 (GRCm38)	missense	possibly damaging	0.82
R1776:Ush2a	UTSW	1	188,728,203 (GRCm38)	missense	possibly damaging	0.83
R1782:Ush2a	UTSW	1	188,911,185 (GRCm38)	missense	probably benign	0.06
R1794:Ush2a	UTSW	1	188,862,809 (GRCm38)	missense	probably benign	0.00
R1796:Ush2a	UTSW	1	188,910,827 (GRCm38)	missense	probably benign	0.11
R1804:Ush2a	UTSW	1	188,633,729 (GRCm38)	critical splice donor site	probably null
R1835:Ush2a	UTSW	1	188,451,818 (GRCm38)	missense	probably benign	0.13
R1871:Ush2a	UTSW	1	188,826,468 (GRCm38)	missense	probably benign	0.02
R1876:Ush2a	UTSW	1	188,678,289 (GRCm38)	missense	possibly damaging	0.51
R1887:Ush2a	UTSW	1	188,399,980 (GRCm38)	missense	probably benign	0.05
R1896:Ush2a	UTSW	1	188,550,009 (GRCm38)	missense	probably benign	0.00
R1907:Ush2a	UTSW	1	188,715,064 (GRCm38)	missense	probably benign	0.01
R1940:Ush2a	UTSW	1	188,951,561 (GRCm38)	missense	probably null	0.89
R1950:Ush2a	UTSW	1	188,755,185 (GRCm38)	missense	probably damaging	1.00
R1991:Ush2a	UTSW	1	188,578,532 (GRCm38)	splice site	probably benign
R2043:Ush2a	UTSW	1	188,916,256 (GRCm38)	missense	probably benign	0.00
R2046:Ush2a	UTSW	1	188,356,927 (GRCm38)	missense	probably benign	0.01
R2059:Ush2a	UTSW	1	188,381,549 (GRCm38)	critical splice donor site	probably null
R2239:Ush2a	UTSW	1	188,576,214 (GRCm38)	missense	probably benign
R2365:Ush2a	UTSW	1	188,378,991 (GRCm38)	missense	possibly damaging	0.68
R2395:Ush2a	UTSW	1	188,947,040 (GRCm38)	missense	probably damaging	1.00
R2425:Ush2a	UTSW	1	188,537,804 (GRCm38)	missense	possibly damaging	0.82
R2519:Ush2a	UTSW	1	188,267,107 (GRCm38)	missense	probably benign
R3039:Ush2a	UTSW	1	188,911,547 (GRCm38)	missense	probably damaging	0.99
R3434:Ush2a	UTSW	1	188,733,758 (GRCm38)	missense	probably damaging	1.00
R3711:Ush2a	UTSW	1	188,810,292 (GRCm38)	missense	probably benign	0.05
R3712:Ush2a	UTSW	1	188,810,292 (GRCm38)	missense	probably benign	0.05
R3732:Ush2a	UTSW	1	188,944,760 (GRCm38)	missense	probably benign	0.16
R3746:Ush2a	UTSW	1	188,810,292 (GRCm38)	missense	probably benign	0.05
R3747:Ush2a	UTSW	1	188,810,292 (GRCm38)	missense	probably benign	0.05
R3883:Ush2a	UTSW	1	188,263,382 (GRCm38)	missense	probably benign
R3911:Ush2a	UTSW	1	188,399,954 (GRCm38)	missense	probably benign	0.05
R3934:Ush2a	UTSW	1	188,263,511 (GRCm38)	critical splice donor site	probably null
R3946:Ush2a	UTSW	1	188,728,504 (GRCm38)	missense	probably benign	0.01
R3974:Ush2a	UTSW	1	188,381,501 (GRCm38)	missense	probably benign	0.06
R4158:Ush2a	UTSW	1	188,728,710 (GRCm38)	missense	probably damaging	1.00
R4159:Ush2a	UTSW	1	188,728,710 (GRCm38)	missense	probably damaging	1.00
R4161:Ush2a	UTSW	1	188,728,710 (GRCm38)	missense	probably damaging	1.00
R4162:Ush2a	UTSW	1	188,743,680 (GRCm38)	missense	probably benign	0.00
R4255:Ush2a	UTSW	1	188,759,843 (GRCm38)	nonsense	probably null
R4280:Ush2a	UTSW	1	188,578,461 (GRCm38)	missense	probably benign	0.16
R4387:Ush2a	UTSW	1	188,443,431 (GRCm38)	missense	probably benign	0.00
R4416:Ush2a	UTSW	1	188,356,874 (GRCm38)	missense	probably damaging	0.97
R4494:Ush2a	UTSW	1	188,553,276 (GRCm38)	missense	possibly damaging	0.50
R4505:Ush2a	UTSW	1	188,728,596 (GRCm38)	missense	possibly damaging	0.92
R4522:Ush2a	UTSW	1	188,864,625 (GRCm38)	missense	probably damaging	1.00
R4584:Ush2a	UTSW	1	188,451,798 (GRCm38)	missense	probably benign	0.00
R4599:Ush2a	UTSW	1	188,911,647 (GRCm38)	missense	probably benign	0.01
R4605:Ush2a	UTSW	1	188,910,801 (GRCm38)	missense	probably damaging	1.00
R4632:Ush2a	UTSW	1	188,395,874 (GRCm38)	missense	possibly damaging	0.82
R4688:Ush2a	UTSW	1	188,399,941 (GRCm38)	missense	probably benign	0.01
R4751:Ush2a	UTSW	1	188,850,087 (GRCm38)	missense	probably damaging	0.98
R4770:Ush2a	UTSW	1	188,549,879 (GRCm38)	missense	probably benign	0.25
R4771:Ush2a	UTSW	1	188,797,769 (GRCm38)	missense	possibly damaging	0.92
R4798:Ush2a	UTSW	1	188,743,545 (GRCm38)	missense	probably damaging	1.00
R4821:Ush2a	UTSW	1	188,753,651 (GRCm38)	missense	probably benign	0.32
R4857:Ush2a	UTSW	1	188,537,720 (GRCm38)	missense	probably benign	0.01
R4860:Ush2a	UTSW	1	188,553,275 (GRCm38)	missense	probably benign	0.07
R4860:Ush2a	UTSW	1	188,553,275 (GRCm38)	missense	probably benign	0.07
R4898:Ush2a	UTSW	1	188,626,608 (GRCm38)	missense	probably benign	0.37
R4993:Ush2a	UTSW	1	188,910,720 (GRCm38)	missense	probably benign	0.03
R5035:Ush2a	UTSW	1	188,910,808 (GRCm38)	missense	probably damaging	1.00
R5061:Ush2a	UTSW	1	188,957,274 (GRCm38)	missense	probably benign	0.03
R5150:Ush2a	UTSW	1	188,451,870 (GRCm38)	missense	possibly damaging	0.95
R5205:Ush2a	UTSW	1	188,874,936 (GRCm38)	missense	probably benign	0.21
R5212:Ush2a	UTSW	1	188,444,705 (GRCm38)	critical splice donor site	probably null
R5252:Ush2a	UTSW	1	188,821,717 (GRCm38)	missense	possibly damaging	0.83
R5260:Ush2a	UTSW	1	188,947,079 (GRCm38)	missense	possibly damaging	0.95
R5304:Ush2a	UTSW	1	188,356,798 (GRCm38)	missense	probably damaging	0.99
R5323:Ush2a	UTSW	1	188,821,677 (GRCm38)	critical splice acceptor site	probably null
R5330:Ush2a	UTSW	1	188,728,381 (GRCm38)	missense	probably benign	0.00
R5331:Ush2a	UTSW	1	188,728,381 (GRCm38)	missense	probably benign	0.00
R5332:Ush2a	UTSW	1	188,351,079 (GRCm38)	missense	probably damaging	1.00
R5371:Ush2a	UTSW	1	188,443,070 (GRCm38)	missense	probably benign	0.00
R5374:Ush2a	UTSW	1	188,755,206 (GRCm38)	missense	probably benign
R5377:Ush2a	UTSW	1	188,912,123 (GRCm38)	missense	probably benign	0.00
R5525:Ush2a	UTSW	1	188,753,606 (GRCm38)	missense	probably benign	0.01
R5558:Ush2a	UTSW	1	188,797,827 (GRCm38)	missense	possibly damaging	0.47
R5562:Ush2a	UTSW	1	188,576,217 (GRCm38)	missense	probably damaging	1.00
R5595:Ush2a	UTSW	1	188,906,498 (GRCm38)	missense	possibly damaging	0.95
R5620:Ush2a	UTSW	1	188,759,823 (GRCm38)	missense	possibly damaging	0.82
R5714:Ush2a	UTSW	1	188,400,257 (GRCm38)	missense	probably benign	0.00
R5743:Ush2a	UTSW	1	188,436,962 (GRCm38)	missense	probably benign	0.01
R5779:Ush2a	UTSW	1	188,443,510 (GRCm38)	critical splice donor site	probably null
R5795:Ush2a	UTSW	1	188,443,397 (GRCm38)	missense	probably benign	0.34
R5897:Ush2a	UTSW	1	188,821,738 (GRCm38)	missense	probably damaging	1.00
R5918:Ush2a	UTSW	1	188,356,814 (GRCm38)	missense	probably benign	0.26
R6000:Ush2a	UTSW	1	188,267,026 (GRCm38)	nonsense	probably null
R6014:Ush2a	UTSW	1	188,850,040 (GRCm38)	missense	probably damaging	0.98
R6017:Ush2a	UTSW	1	188,957,514 (GRCm38)	critical splice donor site	probably null
R6020:Ush2a	UTSW	1	188,728,096 (GRCm38)	splice site	probably null
R6039:Ush2a	UTSW	1	188,319,020 (GRCm38)	missense	possibly damaging	0.76
R6039:Ush2a	UTSW	1	188,319,020 (GRCm38)	missense	possibly damaging	0.76
R6050:Ush2a	UTSW	1	188,957,324 (GRCm38)	missense	probably benign	0.06
R6083:Ush2a	UTSW	1	188,267,023 (GRCm38)	missense	probably damaging	1.00
R6091:Ush2a	UTSW	1	188,399,803 (GRCm38)	missense	probably damaging	1.00
R6120:Ush2a	UTSW	1	188,358,603 (GRCm38)	missense	probably benign	0.04
R6135:Ush2a	UTSW	1	188,912,106 (GRCm38)	missense	possibly damaging	0.68
R6141:Ush2a	UTSW	1	188,357,963 (GRCm38)	missense	possibly damaging	0.71
R6157:Ush2a	UTSW	1	188,728,270 (GRCm38)	missense	probably benign	0.00
R6180:Ush2a	UTSW	1	188,399,871 (GRCm38)	nonsense	probably null
R6191:Ush2a	UTSW	1	188,263,101 (GRCm38)	nonsense	probably null
R6217:Ush2a	UTSW	1	188,743,454 (GRCm38)	splice site	probably null
R6263:Ush2a	UTSW	1	188,358,642 (GRCm38)	missense	probably damaging	1.00
R6294:Ush2a	UTSW	1	188,536,370 (GRCm38)	missense	possibly damaging	0.49
R6320:Ush2a	UTSW	1	188,356,846 (GRCm38)	missense	probably benign	0.01
R6321:Ush2a	UTSW	1	188,849,046 (GRCm38)	nonsense	probably null
R6347:Ush2a	UTSW	1	188,910,887 (GRCm38)	missense	probably benign
R6382:Ush2a	UTSW	1	188,814,302 (GRCm38)	missense	probably benign	0.01
R6408:Ush2a	UTSW	1	188,267,032 (GRCm38)	nonsense	probably null
R6418:Ush2a	UTSW	1	188,628,566 (GRCm38)	missense	probably damaging	1.00
R6500:Ush2a	UTSW	1	188,841,527 (GRCm38)	missense	probably benign	0.00
R6504:Ush2a	UTSW	1	188,911,247 (GRCm38)	missense	probably benign	0.00
R6534:Ush2a	UTSW	1	188,451,802 (GRCm38)	nonsense	probably null
R6594:Ush2a	UTSW	1	188,910,798 (GRCm38)	missense	possibly damaging	0.93
R6612:Ush2a	UTSW	1	188,911,397 (GRCm38)	missense	possibly damaging	0.91
R6645:Ush2a	UTSW	1	188,523,331 (GRCm38)	missense	probably damaging	0.99
R6658:Ush2a	UTSW	1	188,814,359 (GRCm38)	missense	possibly damaging	0.95
R6726:Ush2a	UTSW	1	188,753,684 (GRCm38)	missense	possibly damaging	0.85
R6755:Ush2a	UTSW	1	188,443,219 (GRCm38)	missense	possibly damaging	0.95
R6782:Ush2a	UTSW	1	188,356,834 (GRCm38)	missense	probably benign
R6817:Ush2a	UTSW	1	188,862,864 (GRCm38)	missense	probably benign	0.03
R6834:Ush2a	UTSW	1	188,356,792 (GRCm38)	missense	probably damaging	1.00
R6851:Ush2a	UTSW	1	188,533,205 (GRCm38)	missense	probably benign	0.06
R6853:Ush2a	UTSW	1	188,911,237 (GRCm38)	nonsense	probably null
R6867:Ush2a	UTSW	1	188,910,973 (GRCm38)	missense	probably damaging	1.00
R6889:Ush2a	UTSW	1	188,797,871 (GRCm38)	missense	probably damaging	1.00
R6931:Ush2a	UTSW	1	188,728,383 (GRCm38)	missense	probably benign	0.01
R6953:Ush2a	UTSW	1	188,263,145 (GRCm38)	missense	possibly damaging	0.94
R6966:Ush2a	UTSW	1	188,576,244 (GRCm38)	missense	probably damaging	1.00
R7109:Ush2a	UTSW	1	188,381,484 (GRCm38)	missense	probably benign	0.19
R7153:Ush2a	UTSW	1	188,728,484 (GRCm38)	missense	possibly damaging	0.93
R7176:Ush2a	UTSW	1	188,537,728 (GRCm38)	missense	probably benign	0.00
R7182:Ush2a	UTSW	1	188,753,543 (GRCm38)	missense	probably benign	0.01
R7201:Ush2a	UTSW	1	188,874,754 (GRCm38)	missense	probably benign
R7223:Ush2a	UTSW	1	188,810,217 (GRCm38)	missense	probably benign	0.09
R7231:Ush2a	UTSW	1	188,759,763 (GRCm38)	missense	possibly damaging	0.49
R7240:Ush2a	UTSW	1	188,911,661 (GRCm38)	missense	possibly damaging	0.83
R7263:Ush2a	UTSW	1	188,443,329 (GRCm38)	missense	possibly damaging	0.94
R7329:Ush2a	UTSW	1	188,553,198 (GRCm38)	missense	probably damaging	0.97
R7343:Ush2a	UTSW	1	188,415,746 (GRCm38)	missense	probably benign	0.00
R7352:Ush2a	UTSW	1	188,466,124 (GRCm38)	missense	probably benign	0.04
R7384:Ush2a	UTSW	1	188,400,163 (GRCm38)	missense	probably damaging	0.99
R7391:Ush2a	UTSW	1	188,962,008 (GRCm38)	small deletion	probably benign
R7394:Ush2a	UTSW	1	188,911,416 (GRCm38)	missense	possibly damaging	0.83
R7403:Ush2a	UTSW	1	188,633,727 (GRCm38)	missense	probably damaging	1.00
R7408:Ush2a	UTSW	1	188,733,529 (GRCm38)	missense	probably benign	0.00
R7453:Ush2a	UTSW	1	188,553,111 (GRCm38)	missense	probably damaging	1.00
R7496:Ush2a	UTSW	1	188,351,087 (GRCm38)	missense	possibly damaging	0.50
R7552:Ush2a	UTSW	1	188,267,044 (GRCm38)	missense	possibly damaging	0.65
R7556:Ush2a	UTSW	1	188,957,493 (GRCm38)	missense	probably benign	0.31
R7575:Ush2a	UTSW	1	188,822,688 (GRCm38)	missense	possibly damaging	0.90
R7578:Ush2a	UTSW	1	188,549,913 (GRCm38)	missense	probably damaging	1.00
R7584:Ush2a	UTSW	1	188,728,109 (GRCm38)	critical splice acceptor site	probably null
R7589:Ush2a	UTSW	1	188,542,849 (GRCm38)	missense	probably benign	0.00
R7602:Ush2a	UTSW	1	188,648,409 (GRCm38)	missense	probably damaging	1.00
R7670:Ush2a	UTSW	1	188,784,708 (GRCm38)	missense	possibly damaging	0.78
R7743:Ush2a	UTSW	1	188,810,179 (GRCm38)	missense	probably benign	0.05
R7753:Ush2a	UTSW	1	188,443,406 (GRCm38)	missense	probably benign	0.28
R7767:Ush2a	UTSW	1	188,553,260 (GRCm38)	missense	probably benign	0.01
R7784:Ush2a	UTSW	1	188,444,592 (GRCm38)	missense	possibly damaging	0.55
R7831:Ush2a	UTSW	1	188,759,841 (GRCm38)	missense	probably damaging	0.98
R7834:Ush2a	UTSW	1	188,733,440 (GRCm38)	nonsense	probably null
R7847:Ush2a	UTSW	1	188,430,808 (GRCm38)	missense	probably damaging	1.00
R7926:Ush2a	UTSW	1	188,728,600 (GRCm38)	missense	probably benign
R7969:Ush2a	UTSW	1	188,826,371 (GRCm38)	missense	probably benign	0.02
R7978:Ush2a	UTSW	1	188,399,938 (GRCm38)	missense	probably benign	0.00
R7990:Ush2a	UTSW	1	188,542,799 (GRCm38)	missense	probably benign	0.00
R8001:Ush2a	UTSW	1	188,911,064 (GRCm38)	missense	probably damaging	0.98
R8039:Ush2a	UTSW	1	188,957,373 (GRCm38)	missense	probably damaging	1.00
R8077:Ush2a	UTSW	1	188,542,828 (GRCm38)	missense	probably benign	0.01
R8165:Ush2a	UTSW	1	188,451,755 (GRCm38)	missense	possibly damaging	0.70
R8208:Ush2a	UTSW	1	188,874,793 (GRCm38)	missense	possibly damaging	0.95
R8220:Ush2a	UTSW	1	188,728,666 (GRCm38)	missense	probably damaging	1.00
R8270:Ush2a	UTSW	1	188,444,641 (GRCm38)	missense	probably benign	0.06
R8316:Ush2a	UTSW	1	188,446,702 (GRCm38)	missense	probably benign	0.01
R8347:Ush2a	UTSW	1	188,947,084 (GRCm38)	missense	probably benign	0.02
R8360:Ush2a	UTSW	1	188,466,271 (GRCm38)	missense	probably benign	0.01
R8362:Ush2a	UTSW	1	188,957,453 (GRCm38)	missense	probably damaging	0.96
R8386:Ush2a	UTSW	1	188,728,206 (GRCm38)	missense	possibly damaging	0.80
R8401:Ush2a	UTSW	1	188,542,865 (GRCm38)	missense	probably benign	0.10
R8439:Ush2a	UTSW	1	188,850,057 (GRCm38)	missense	probably damaging	1.00
R8465:Ush2a	UTSW	1	188,415,678 (GRCm38)	missense	probably damaging	1.00
R8478:Ush2a	UTSW	1	188,443,232 (GRCm38)	missense	possibly damaging	0.83
R8540:Ush2a	UTSW	1	188,542,661 (GRCm38)	missense	probably benign	0.00
R8684:Ush2a	UTSW	1	188,911,023 (GRCm38)	missense	possibly damaging	0.45
R8685:Ush2a	UTSW	1	188,466,204 (GRCm38)	missense	probably damaging	1.00
R8699:Ush2a	UTSW	1	188,911,377 (GRCm38)	missense	probably damaging	1.00
R8720:Ush2a	UTSW	1	188,358,518 (GRCm38)	missense	probably benign	0.05
R8754:Ush2a	UTSW	1	188,848,965 (GRCm38)	nonsense	probably null
R8756:Ush2a	UTSW	1	188,911,944 (GRCm38)	missense	possibly damaging	0.91
R8788:Ush2a	UTSW	1	188,743,619 (GRCm38)	nonsense	probably null
R8803:Ush2a	UTSW	1	188,944,801 (GRCm38)	missense	probably benign
R8817:Ush2a	UTSW	1	188,263,034 (GRCm38)	start codon destroyed	probably benign	0.00
R8837:Ush2a	UTSW	1	188,753,650 (GRCm38)	missense	probably benign
R8880:Ush2a	UTSW	1	188,728,536 (GRCm38)	missense	probably benign	0.11
R8902:Ush2a	UTSW	1	188,443,084 (GRCm38)	missense	probably damaging	0.98
R8918:Ush2a	UTSW	1	188,537,820 (GRCm38)	missense	possibly damaging	0.85
R8940:Ush2a	UTSW	1	188,400,308 (GRCm38)	missense	probably benign	0.02
R8968:Ush2a	UTSW	1	188,395,759 (GRCm38)	missense	probably damaging	1.00
R8995:Ush2a	UTSW	1	188,444,653 (GRCm38)	missense	probably damaging	0.98
R9011:Ush2a	UTSW	1	188,906,479 (GRCm38)	missense	probably damaging	0.99
R9037:Ush2a	UTSW	1	188,263,290 (GRCm38)	missense	possibly damaging	0.51
R9063:Ush2a	UTSW	1	188,263,260 (GRCm38)	missense	probably benign	0.00
R9089:Ush2a	UTSW	1	188,755,177 (GRCm38)	nonsense	probably null
R9096:Ush2a	UTSW	1	188,466,136 (GRCm38)	missense	probably benign	0.00
R9118:Ush2a	UTSW	1	188,654,642 (GRCm38)	missense	probably damaging	0.98
R9174:Ush2a	UTSW	1	188,728,219 (GRCm38)	missense	probably damaging	0.99
R9210:Ush2a	UTSW	1	188,784,669 (GRCm38)	missense	probably null	0.01
R9242:Ush2a	UTSW	1	188,633,590 (GRCm38)	missense	probably damaging	1.00
R9321:Ush2a	UTSW	1	188,356,951 (GRCm38)	missense	probably damaging	0.97
R9338:Ush2a	UTSW	1	188,576,292 (GRCm38)	critical splice donor site	probably null
R9357:Ush2a	UTSW	1	188,874,950 (GRCm38)	missense	probably benign	0.01
R9358:Ush2a	UTSW	1	188,874,950 (GRCm38)	missense	probably benign	0.01
R9406:Ush2a	UTSW	1	188,263,449 (GRCm38)	missense	probably benign	0.00
R9407:Ush2a	UTSW	1	188,911,848 (GRCm38)	missense	probably damaging	1.00
R9428:Ush2a	UTSW	1	188,443,119 (GRCm38)	missense	probably damaging	1.00
R9456:Ush2a	UTSW	1	188,826,392 (GRCm38)	missense	probably benign	0.00
R9507:Ush2a	UTSW	1	188,864,740 (GRCm38)	nonsense	probably null
R9509:Ush2a	UTSW	1	188,916,243 (GRCm38)	missense	probably damaging	1.00
R9512:Ush2a	UTSW	1	188,910,963 (GRCm38)	missense	probably damaging	0.99
R9564:Ush2a	UTSW	1	188,536,354 (GRCm38)	missense	possibly damaging	0.90
R9612:Ush2a	UTSW	1	188,359,866 (GRCm38)	nonsense	probably null
R9670:Ush2a	UTSW	1	188,628,571 (GRCm38)	missense	probably benign	0.03
R9684:Ush2a	UTSW	1	188,399,881 (GRCm38)	missense	possibly damaging	0.67
R9798:Ush2a	UTSW	1	188,911,805 (GRCm38)	missense	possibly damaging	0.80
RF017:Ush2a	UTSW	1	188,263,469 (GRCm38)	missense	probably damaging	1.00
U24488:Ush2a	UTSW	1	188,430,766 (GRCm38)	missense	probably damaging	0.99
X0011:Ush2a	UTSW	1	188,318,969 (GRCm38)	missense	probably benign	0.00
X0024:Ush2a	UTSW	1	188,400,282 (GRCm38)	missense	probably damaging	1.00
X0026:Ush2a	UTSW	1	188,319,025 (GRCm38)	missense	possibly damaging	0.94
X0062:Ush2a	UTSW	1	188,549,854 (GRCm38)	missense	probably damaging	1.00
Y4340:Ush2a	UTSW	1	188,743,629 (GRCm38)	missense	possibly damaging	0.87
Y4341:Ush2a	UTSW	1	188,743,629 (GRCm38)	missense	possibly damaging	0.87
Z1088:Ush2a	UTSW	1	188,947,004 (GRCm38)	missense	probably benign	0.26
Z1088:Ush2a	UTSW	1	188,911,983 (GRCm38)	missense	probably benign
Z1176:Ush2a	UTSW	1	188,356,841 (GRCm38)	missense	probably damaging	1.00
Z1177:Ush2a	UTSW	1	188,912,210 (GRCm38)	missense	possibly damaging	0.77
Z1177:Ush2a	UTSW	1	188,733,544 (GRCm38)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- AGCACAAAGTCATGTTGGTCAGACATT -3'
(R):5'- GGGCAAATCCCTCCTTCTCCCTA -3'

Sequencing Primer
(F):5'- AGGGATGGCACTAACACTTG -3'
(R):5'- AGCCATCACCTCTCACATTCTG -3'

Posted On

2013-07-30