Mutagenetix > Incidental Mutation

Incidental Mutation 'R8223:Ptprq'

636839

Institutional Source

Beutler Lab

Gene Symbol

Ptprq

Ensembl Gene

ENSMUSG00000035916

Gene Name

protein tyrosine phosphatase receptor type Q

Synonyms

MMRRC Submission

067641-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.236) question?

Stock #

R8223 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

107352910-107555912 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 107535499 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Glutamine at position 422 (R422Q)

Ref Sequence

ENSEMBL: ENSMUSP00000058572 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000050702]

AlphaFold

P0C5E4

Predicted Effect

probably benign
Transcript: ENSMUST00000050702
AA Change: R422Q

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000058572
Gene: ENSMUSG00000035916
AA Change: R422Q

Domain	Start	End	E-Value	Type
FN3	57	141	3.17e-13	SMART
FN3	156	294	1.55e-7	SMART
FN3	307	384	4.45e-8	SMART
FN3	398	555	1.17e-7	SMART
FN3	569	648	7.06e-11	SMART
FN3	666	743	7.68e-12	SMART
FN3	760	839	1.88e-6	SMART
FN3	855	932	1.33e-6	SMART
FN3	949	1037	2.31e-6	SMART
FN3	1054	1135	1.24e-6	SMART
FN3	1151	1229	2.39e-8	SMART
FN3	1244	1325	6.29e-8	SMART
FN3	1341	1416	2.87e-11	SMART
FN3	1431	1524	2.82e-10	SMART
FN3	1540	1622	6.35e-4	SMART
FN3	1642	1732	7.93e-5	SMART
transmembrane domain	1907	1929	N/A	INTRINSIC
PTPc	2003	2262	1.14e-130	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.8%
10x: 99.4%
20x: 98.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation and differentiation. Mutations at this locus have been linked to autosomal recessive deafness. [provided by RefSeq, Mar 2014]
PHENOTYPE: Homozygotes for targeted mutations show absence of shaft connectors from vestibular hair bundles, postnatal degeneration in cochlear hair-bundle structure, reduced transducer currents but otherwise normal adaptation properties, a progressive loss of basal-coil cochlear hair cells, and deafness. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 68 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgre1	T	A	17: 57,668,692 (GRCm39)	W18R	probably damaging	Het
Alms1	T	A	6: 85,620,222 (GRCm39)	Y2417*	probably null	Het
Apold1	T	A	6: 134,961,148 (GRCm39)	S201T	probably benign	Het
Arhgap31	G	A	16: 38,424,084 (GRCm39)	P661S	probably benign	Het
Cacfd1	T	C	2: 26,908,396 (GRCm39)	V110A	possibly damaging	Het
Capn2	A	G	1: 182,310,099 (GRCm39)		probably null	Het
Chadl	T	C	15: 81,579,335 (GRCm39)	E98G	possibly damaging	Het
Crxos	T	C	7: 15,631,394 (GRCm39)	Y31H	probably benign	Het
Cyp4f14	A	C	17: 33,130,627 (GRCm39)		probably null	Het
Cyp4f39	T	C	17: 32,689,839 (GRCm39)	I95T	probably benign	Het
Dars1	T	C	1: 128,299,961 (GRCm39)	E341G	probably benign	Het
Dchs1	G	T	7: 105,411,824 (GRCm39)	R1431S	possibly damaging	Het
Dop1a	T	A	9: 86,400,345 (GRCm39)	H1001Q	probably damaging	Het
Efemp1	T	C	11: 28,804,528 (GRCm39)	Y19H	probably benign	Het
Eml1	T	G	12: 108,502,569 (GRCm39)	F726V	probably benign	Het
Fdx1	A	T	9: 51,859,921 (GRCm39)	D136E	probably benign	Het
Ganab	A	T	19: 8,888,192 (GRCm39)	D446V	probably damaging	Het
Gusb	A	G	5: 130,018,953 (GRCm39)	V561A	probably benign	Het
Hcn1	A	T	13: 118,010,406 (GRCm39)	D328V	unknown	Het
Hdgfl1	A	G	13: 26,954,047 (GRCm39)	Y9H	probably damaging	Het
Hes3	T	A	4: 152,371,572 (GRCm39)	S101C	probably damaging	Het
Igkv2-112	T	C	6: 68,197,579 (GRCm39)	S84P	probably benign	Het
Ints9	C	T	14: 65,257,809 (GRCm39)	P330S	possibly damaging	Het
Kdm7a	A	T	6: 39,126,235 (GRCm39)	N583K	probably damaging	Het
Klhl10	C	T	11: 100,338,227 (GRCm39)	T322M	probably damaging	Het
Kmt2c	A	T	5: 25,529,216 (GRCm39)	V1545D	possibly damaging	Het
Laptm5	T	C	4: 130,653,511 (GRCm39)		probably null	Het
Ldlr	A	G	9: 21,658,546 (GRCm39)	T833A	probably damaging	Het
Llgl1	G	T	11: 60,593,648 (GRCm39)	L40F	possibly damaging	Het
Lrrc14	T	C	15: 76,598,756 (GRCm39)	L464S	probably damaging	Het
Lrrc38	G	A	4: 143,077,303 (GRCm39)	G189R	probably damaging	Het
Lysmd3	T	A	13: 81,817,386 (GRCm39)	L121H		Het
Map2	T	C	1: 66,464,649 (GRCm39)	S1680P	probably damaging	Het
Med12l	T	C	3: 58,993,784 (GRCm39)	V583A	possibly damaging	Het
Mfsd4b5	A	G	10: 39,846,246 (GRCm39)	Y445H	probably damaging	Het
Morf4l1	G	A	9: 89,979,475 (GRCm39)	P169S	probably benign	Het
Nab2	C	A	10: 127,498,645 (GRCm39)	V475L	probably benign	Het
Ola1	A	G	2: 72,929,694 (GRCm39)	L303P	probably damaging	Het
Or1j19	T	A	2: 36,677,409 (GRCm39)	Y291N		Het
Or1o2	T	C	17: 37,542,727 (GRCm39)	D178G	possibly damaging	Het
Or7e166	T	C	9: 19,624,705 (GRCm39)	I194T	probably benign	Het
Or9i2	G	T	19: 13,816,225 (GRCm39)	T104K	probably damaging	Het
Pdlim3	A	T	8: 46,353,562 (GRCm39)	H99L	possibly damaging	Het
Plagl2	G	T	2: 153,073,461 (GRCm39)	T480N	probably benign	Het
Pramel20	T	G	4: 143,298,530 (GRCm39)	Y158D	probably benign	Het
Rad18	T	A	6: 112,664,982 (GRCm39)	R51*	probably null	Het
Rpap3	T	A	15: 97,589,185 (GRCm39)	T250S	probably benign	Het
Serpinb11	T	C	1: 107,305,262 (GRCm39)	Y213H	probably benign	Het
Slc15a4	A	G	5: 127,686,080 (GRCm39)	F201L	possibly damaging	Het
Slc25a4	A	G	8: 46,663,896 (GRCm39)	S22P	probably damaging	Het
Slfn1	T	A	11: 83,012,245 (GRCm39)	N120K	probably damaging	Het
Smok3c	T	C	5: 138,063,655 (GRCm39)	S381P	probably benign	Het
Sry	T	A	Y: 2,663,204 (GRCm39)	Q152L	unknown	Het
Taar2	T	A	10: 23,817,248 (GRCm39)	W263R	probably damaging	Het
Thnsl1	T	A	2: 21,216,924 (GRCm39)	V226E	probably benign	Het
Tmeff2	T	C	1: 51,172,279 (GRCm39)		probably null	Het
Tox	A	G	4: 6,842,408 (GRCm39)	Y41H	probably damaging	Het
Trank1	T	A	9: 111,194,957 (GRCm39)	Y994N	probably damaging	Het
Trim9	C	T	12: 70,297,789 (GRCm39)	A713T	probably damaging	Het
Tub	T	A	7: 108,628,533 (GRCm39)	M393K	probably benign	Het
Ube4a	A	G	9: 44,871,333 (GRCm39)	L22P	possibly damaging	Het
Usp47	A	G	7: 111,703,583 (GRCm39)	K1165R	probably damaging	Het
Usp6nl	T	A	2: 6,435,327 (GRCm39)	I362K	probably damaging	Het
Vmn1r217	T	C	13: 23,298,369 (GRCm39)	I178V	probably benign	Het
Vmn1r45	T	A	6: 89,910,074 (GRCm39)	T299S	probably damaging	Het
Vmn2r5	A	T	3: 64,398,726 (GRCm39)	L751*	probably null	Het
Xkr8	G	A	4: 132,458,246 (GRCm39)	P144L	probably damaging	Het
Zfpm2	T	C	15: 40,616,355 (GRCm39)	I35T	probably benign	Het

Other mutations in Ptprq

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00340:Ptprq	APN	10	107,412,790 (GRCm39)	missense	probably damaging	0.98
IGL00537:Ptprq	APN	10	107,546,383 (GRCm39)	missense	probably benign	0.07
IGL00547:Ptprq	APN	10	107,554,402 (GRCm39)	missense	probably damaging	0.99
IGL00586:Ptprq	APN	10	107,443,983 (GRCm39)	splice site	probably benign
IGL00648:Ptprq	APN	10	107,482,577 (GRCm39)	missense	probably benign	0.10
IGL01123:Ptprq	APN	10	107,522,079 (GRCm39)	missense	probably damaging	0.96
IGL01343:Ptprq	APN	10	107,474,700 (GRCm39)	missense	probably damaging	0.96
IGL01348:Ptprq	APN	10	107,547,765 (GRCm39)	missense	probably damaging	1.00
IGL01433:Ptprq	APN	10	107,412,741 (GRCm39)	missense	probably damaging	0.99
IGL01510:Ptprq	APN	10	107,547,909 (GRCm39)	missense	probably damaging	1.00
IGL01535:Ptprq	APN	10	107,535,457 (GRCm39)	missense	probably benign
IGL01631:Ptprq	APN	10	107,479,399 (GRCm39)	missense	probably benign	0.00
IGL01633:Ptprq	APN	10	107,535,584 (GRCm39)	splice site	probably benign
IGL01702:Ptprq	APN	10	107,353,727 (GRCm39)	missense	probably benign	0.00
IGL01733:Ptprq	APN	10	107,498,460 (GRCm39)	missense	probably benign	0.10
IGL01806:Ptprq	APN	10	107,535,469 (GRCm39)	missense	probably damaging	1.00
IGL01832:Ptprq	APN	10	107,401,700 (GRCm39)	critical splice donor site	probably null
IGL01961:Ptprq	APN	10	107,479,515 (GRCm39)	missense	probably damaging	1.00
IGL02108:Ptprq	APN	10	107,482,478 (GRCm39)	missense	probably damaging	1.00
IGL02120:Ptprq	APN	10	107,503,333 (GRCm39)	missense	probably damaging	1.00
IGL02160:Ptprq	APN	10	107,489,426 (GRCm39)	missense	probably benign	0.00
IGL02178:Ptprq	APN	10	107,522,180 (GRCm39)	missense	probably benign	0.03
IGL02249:Ptprq	APN	10	107,418,220 (GRCm39)	missense	probably damaging	1.00
IGL02267:Ptprq	APN	10	107,482,419 (GRCm39)	missense	probably damaging	1.00
IGL02527:Ptprq	APN	10	107,522,424 (GRCm39)	missense	probably benign	0.04
IGL02529:Ptprq	APN	10	107,471,226 (GRCm39)	missense	probably benign	0.03
IGL02542:Ptprq	APN	10	107,498,416 (GRCm39)	missense	probably damaging	1.00
IGL02582:Ptprq	APN	10	107,479,860 (GRCm39)	missense	probably benign	0.00
IGL02708:Ptprq	APN	10	107,488,561 (GRCm39)	missense	probably damaging	1.00
IGL02894:Ptprq	APN	10	107,503,285 (GRCm39)	missense	probably benign
IGL02903:Ptprq	APN	10	107,502,447 (GRCm39)	missense	possibly damaging	0.51
IGL02951:Ptprq	APN	10	107,503,321 (GRCm39)	missense	probably benign	0.03
IGL02982:Ptprq	APN	10	107,422,545 (GRCm39)	missense	probably damaging	1.00
IGL03000:Ptprq	APN	10	107,378,518 (GRCm39)	missense	probably damaging	1.00
IGL03024:Ptprq	APN	10	107,521,427 (GRCm39)	missense	possibly damaging	0.69
IGL03240:Ptprq	APN	10	107,524,368 (GRCm39)	missense	probably benign
P0043:Ptprq	UTSW	10	107,416,086 (GRCm39)	missense	probably benign	0.03
PIT4812001:Ptprq	UTSW	10	107,502,428 (GRCm39)	missense	probably damaging	1.00
R0200:Ptprq	UTSW	10	107,521,018 (GRCm39)	missense	probably benign
R0268:Ptprq	UTSW	10	107,541,409 (GRCm39)	missense	probably benign
R0276:Ptprq	UTSW	10	107,378,596 (GRCm39)	critical splice acceptor site	probably null
R0279:Ptprq	UTSW	10	107,444,278 (GRCm39)	missense	probably damaging	0.96
R0335:Ptprq	UTSW	10	107,544,589 (GRCm39)	missense	probably benign
R0344:Ptprq	UTSW	10	107,541,443 (GRCm39)	missense	probably benign
R0357:Ptprq	UTSW	10	107,522,060 (GRCm39)	splice site	probably benign
R0454:Ptprq	UTSW	10	107,418,391 (GRCm39)	nonsense	probably null
R0479:Ptprq	UTSW	10	107,479,855 (GRCm39)	nonsense	probably null
R0491:Ptprq	UTSW	10	107,444,036 (GRCm39)	missense	probably damaging	0.98
R0519:Ptprq	UTSW	10	107,374,781 (GRCm39)	splice site	probably benign
R0523:Ptprq	UTSW	10	107,416,081 (GRCm39)	missense	possibly damaging	0.54
R0553:Ptprq	UTSW	10	107,546,488 (GRCm39)	missense	probably benign	0.33
R0746:Ptprq	UTSW	10	107,353,692 (GRCm39)	missense	probably damaging	1.00
R0755:Ptprq	UTSW	10	107,418,400 (GRCm39)	missense	probably benign	0.09
R1434:Ptprq	UTSW	10	107,422,575 (GRCm39)	missense	probably damaging	1.00
R1445:Ptprq	UTSW	10	107,498,423 (GRCm39)	missense	probably damaging	1.00
R1470:Ptprq	UTSW	10	107,554,435 (GRCm39)	missense	probably damaging	0.97
R1470:Ptprq	UTSW	10	107,554,435 (GRCm39)	missense	probably damaging	0.97
R1558:Ptprq	UTSW	10	107,479,904 (GRCm39)	missense	probably damaging	1.00
R1567:Ptprq	UTSW	10	107,401,748 (GRCm39)	missense	probably benign	0.13
R1711:Ptprq	UTSW	10	107,370,560 (GRCm39)	nonsense	probably null
R1720:Ptprq	UTSW	10	107,522,155 (GRCm39)	missense	probably damaging	1.00
R1746:Ptprq	UTSW	10	107,474,691 (GRCm39)	missense	probably damaging	1.00
R1776:Ptprq	UTSW	10	107,520,950 (GRCm39)	missense	probably damaging	1.00
R1822:Ptprq	UTSW	10	107,554,339 (GRCm39)	missense	probably damaging	1.00
R1872:Ptprq	UTSW	10	107,479,860 (GRCm39)	missense	probably benign	0.19
R1944:Ptprq	UTSW	10	107,418,249 (GRCm39)	missense	probably benign	0.23
R1945:Ptprq	UTSW	10	107,418,249 (GRCm39)	missense	probably benign	0.23
R2006:Ptprq	UTSW	10	107,502,407 (GRCm39)	missense	probably damaging	1.00
R2014:Ptprq	UTSW	10	107,503,283 (GRCm39)	missense	probably damaging	0.96
R2015:Ptprq	UTSW	10	107,503,283 (GRCm39)	missense	probably damaging	0.96
R2097:Ptprq	UTSW	10	107,489,354 (GRCm39)	missense	probably benign	0.05
R2172:Ptprq	UTSW	10	107,426,855 (GRCm39)	nonsense	probably null
R2174:Ptprq	UTSW	10	107,541,414 (GRCm39)	missense	probably damaging	1.00
R2248:Ptprq	UTSW	10	107,478,931 (GRCm39)	splice site	probably null
R2404:Ptprq	UTSW	10	107,522,460 (GRCm39)	missense	probably damaging	1.00
R3423:Ptprq	UTSW	10	107,418,337 (GRCm39)	missense	probably damaging	0.99
R3683:Ptprq	UTSW	10	107,544,489 (GRCm39)	missense	probably benign	0.01
R3875:Ptprq	UTSW	10	107,520,965 (GRCm39)	missense	possibly damaging	0.88
R3945:Ptprq	UTSW	10	107,522,253 (GRCm39)	splice site	probably benign
R3946:Ptprq	UTSW	10	107,522,253 (GRCm39)	splice site	probably benign
R3974:Ptprq	UTSW	10	107,547,923 (GRCm39)	missense	possibly damaging	0.88
R3982:Ptprq	UTSW	10	107,379,257 (GRCm39)	missense	probably damaging	0.99
R4105:Ptprq	UTSW	10	107,408,828 (GRCm39)	missense	probably damaging	1.00
R4118:Ptprq	UTSW	10	107,547,781 (GRCm39)	missense	probably benign	0.37
R4175:Ptprq	UTSW	10	107,547,778 (GRCm39)	missense	probably benign
R4231:Ptprq	UTSW	10	107,522,144 (GRCm39)	nonsense	probably null
R4356:Ptprq	UTSW	10	107,444,225 (GRCm39)	missense	probably damaging	0.99
R4435:Ptprq	UTSW	10	107,520,916 (GRCm39)	missense	possibly damaging	0.89
R4678:Ptprq	UTSW	10	107,521,043 (GRCm39)	missense	probably benign	0.19
R4679:Ptprq	UTSW	10	107,521,043 (GRCm39)	missense	probably benign	0.19
R4745:Ptprq	UTSW	10	107,360,114 (GRCm39)	missense	probably damaging	1.00
R4771:Ptprq	UTSW	10	107,524,288 (GRCm39)	missense	probably benign
R4778:Ptprq	UTSW	10	107,426,883 (GRCm39)	missense	probably benign	0.15
R4808:Ptprq	UTSW	10	107,554,368 (GRCm39)	missense	probably damaging	1.00
R4809:Ptprq	UTSW	10	107,399,036 (GRCm39)	missense	probably damaging	1.00
R4818:Ptprq	UTSW	10	107,546,442 (GRCm39)	missense	possibly damaging	0.86
R4845:Ptprq	UTSW	10	107,489,393 (GRCm39)	missense	probably benign	0.00
R4901:Ptprq	UTSW	10	107,524,275 (GRCm39)	missense	probably benign	0.01
R4942:Ptprq	UTSW	10	107,524,290 (GRCm39)	missense	probably benign	0.01
R4946:Ptprq	UTSW	10	107,361,595 (GRCm39)	missense	probably benign
R4959:Ptprq	UTSW	10	107,522,416 (GRCm39)	missense	probably damaging	1.00
R4973:Ptprq	UTSW	10	107,522,416 (GRCm39)	missense	probably damaging	1.00
R5007:Ptprq	UTSW	10	107,444,137 (GRCm39)	missense	probably benign	0.00
R5053:Ptprq	UTSW	10	107,399,063 (GRCm39)	missense	probably damaging	1.00
R5055:Ptprq	UTSW	10	107,370,540 (GRCm39)	missense	probably benign	0.37
R5090:Ptprq	UTSW	10	107,361,950 (GRCm39)	missense	probably damaging	1.00
R5158:Ptprq	UTSW	10	107,370,565 (GRCm39)	missense	probably damaging	1.00
R5163:Ptprq	UTSW	10	107,360,192 (GRCm39)	missense	probably damaging	1.00
R5222:Ptprq	UTSW	10	107,498,425 (GRCm39)	missense	probably damaging	0.96
R5244:Ptprq	UTSW	10	107,422,556 (GRCm39)	missense	possibly damaging	0.62
R5249:Ptprq	UTSW	10	107,535,496 (GRCm39)	missense	probably damaging	0.99
R5503:Ptprq	UTSW	10	107,524,189 (GRCm39)	splice site	probably null
R5508:Ptprq	UTSW	10	107,522,092 (GRCm39)	missense	probably benign	0.00
R5601:Ptprq	UTSW	10	107,444,291 (GRCm39)	missense	probably benign
R5722:Ptprq	UTSW	10	107,522,226 (GRCm39)	missense	possibly damaging	0.72
R5819:Ptprq	UTSW	10	107,555,744 (GRCm39)	start gained	probably benign
R5862:Ptprq	UTSW	10	107,401,739 (GRCm39)	missense	probably benign	0.02
R5891:Ptprq	UTSW	10	107,412,756 (GRCm39)	missense	possibly damaging	0.94
R5916:Ptprq	UTSW	10	107,359,374 (GRCm39)	missense	probably damaging	1.00
R6054:Ptprq	UTSW	10	107,418,219 (GRCm39)	missense	probably damaging	1.00
R6058:Ptprq	UTSW	10	107,471,135 (GRCm39)	missense	probably benign	0.00
R6075:Ptprq	UTSW	10	107,361,621 (GRCm39)	missense	probably damaging	1.00
R6101:Ptprq	UTSW	10	107,416,127 (GRCm39)	missense	possibly damaging	0.93
R6189:Ptprq	UTSW	10	107,353,748 (GRCm39)	missense	probably damaging	1.00
R6235:Ptprq	UTSW	10	107,471,199 (GRCm39)	missense	possibly damaging	0.61
R6351:Ptprq	UTSW	10	107,544,529 (GRCm39)	missense	probably damaging	0.99
R6394:Ptprq	UTSW	10	107,478,804 (GRCm39)	nonsense	probably null
R6449:Ptprq	UTSW	10	107,541,444 (GRCm39)	missense	probably benign	0.00
R6526:Ptprq	UTSW	10	107,378,514 (GRCm39)	nonsense	probably null
R6544:Ptprq	UTSW	10	107,444,102 (GRCm39)	missense	probably damaging	1.00
R6609:Ptprq	UTSW	10	107,408,829 (GRCm39)	missense	probably damaging	0.99
R6862:Ptprq	UTSW	10	107,522,086 (GRCm39)	missense	probably damaging	0.96
R6874:Ptprq	UTSW	10	107,554,460 (GRCm39)	missense	possibly damaging	0.80
R6892:Ptprq	UTSW	10	107,411,865 (GRCm39)	missense	probably benign	0.00
R7082:Ptprq	UTSW	10	107,544,591 (GRCm39)	missense	probably benign	0.10
R7210:Ptprq	UTSW	10	107,521,032 (GRCm39)	missense	probably damaging	1.00
R7253:Ptprq	UTSW	10	107,444,134 (GRCm39)	missense	probably benign	0.30
R7293:Ptprq	UTSW	10	107,471,367 (GRCm39)	nonsense	probably null
R7445:Ptprq	UTSW	10	107,426,820 (GRCm39)	missense	probably damaging	1.00
R7632:Ptprq	UTSW	10	107,547,783 (GRCm39)	missense	probably benign	0.32
R7685:Ptprq	UTSW	10	107,479,839 (GRCm39)	missense	probably damaging	1.00
R7703:Ptprq	UTSW	10	107,480,007 (GRCm39)	missense	probably benign	0.01
R7774:Ptprq	UTSW	10	107,479,530 (GRCm39)	missense	probably damaging	0.96
R7897:Ptprq	UTSW	10	107,546,484 (GRCm39)	missense	probably benign	0.21
R7936:Ptprq	UTSW	10	107,488,572 (GRCm39)	missense	probably damaging	1.00
R7983:Ptprq	UTSW	10	107,444,272 (GRCm39)	nonsense	probably null
R8023:Ptprq	UTSW	10	107,488,477 (GRCm39)	nonsense	probably null
R8071:Ptprq	UTSW	10	107,479,896 (GRCm39)	missense	possibly damaging	0.62
R8084:Ptprq	UTSW	10	107,444,294 (GRCm39)	missense	probably benign
R8086:Ptprq	UTSW	10	107,482,500 (GRCm39)	nonsense	probably null
R8169:Ptprq	UTSW	10	107,418,351 (GRCm39)	missense	probably damaging	1.00
R8235:Ptprq	UTSW	10	107,541,351 (GRCm39)	missense	probably benign	0.32
R8235:Ptprq	UTSW	10	107,418,402 (GRCm39)	missense	probably damaging	1.00
R8278:Ptprq	UTSW	10	107,522,239 (GRCm39)	missense	possibly damaging	0.87
R8710:Ptprq	UTSW	10	107,411,919 (GRCm39)	missense	possibly damaging	0.67
R8828:Ptprq	UTSW	10	107,482,513 (GRCm39)	missense	probably benign
R8830:Ptprq	UTSW	10	107,422,556 (GRCm39)	missense	possibly damaging	0.62
R8869:Ptprq	UTSW	10	107,535,469 (GRCm39)	missense	probably damaging	1.00
R9012:Ptprq	UTSW	10	107,489,411 (GRCm39)	missense	probably benign	0.09
R9072:Ptprq	UTSW	10	107,401,736 (GRCm39)	missense
R9153:Ptprq	UTSW	10	107,416,126 (GRCm39)	missense	probably damaging	0.98
R9202:Ptprq	UTSW	10	107,522,416 (GRCm39)	missense	probably damaging	1.00
R9252:Ptprq	UTSW	10	107,522,247 (GRCm39)	missense	probably benign	0.12
R9306:Ptprq	UTSW	10	107,422,599 (GRCm39)	missense	probably benign	0.00
R9492:Ptprq	UTSW	10	107,478,813 (GRCm39)	missense	probably damaging	1.00
R9519:Ptprq	UTSW	10	107,520,961 (GRCm39)	missense	probably damaging	1.00
R9581:Ptprq	UTSW	10	107,547,771 (GRCm39)	missense	possibly damaging	0.53
R9593:Ptprq	UTSW	10	107,524,254 (GRCm39)	missense	possibly damaging	0.92
R9621:Ptprq	UTSW	10	107,378,523 (GRCm39)	missense	probably damaging	1.00
R9732:Ptprq	UTSW	10	107,412,767 (GRCm39)	missense	probably damaging	1.00
R9743:Ptprq	UTSW	10	107,520,982 (GRCm39)	missense	probably damaging	1.00
R9771:Ptprq	UTSW	10	107,521,085 (GRCm39)	missense	probably damaging	0.99
R9788:Ptprq	UTSW	10	107,401,751 (GRCm39)	missense	probably benign	0.24
Z1088:Ptprq	UTSW	10	107,535,533 (GRCm39)	missense	possibly damaging	0.56
Z1176:Ptprq	UTSW	10	107,361,931 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GTGATCTACTTAACCTGTCAACATACC -3'
(R):5'- TTCTAGTCAGTTTTCCCAGAGC -3'

Sequencing Primer
(F):5'- TGTAGAAATTTGACAAACTGGCC -3'
(R):5'- GTCAGTTTTCCCAGAGCTATTTATAC -3'

Posted On

2020-07-13