Incidental Mutation 'R0718:Pcnx3'
| ID |
63735 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx3
|
| Ensembl Gene |
ENSMUSG00000054874 |
| Gene Name |
pecanex homolog 3 |
| Synonyms |
Pcnxl3 |
| MMRRC Submission |
038900-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0718 (G1)
|
| Quality Score |
101 |
|
Status
|
Validated
|
| Chromosome |
19 |
| Chromosomal Location |
5714663-5738936 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
G to A
at 5727756 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068169]
[ENSMUST00000113615]
[ENSMUST00000141577]
|
| AlphaFold |
Q8VI59 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000068169
|
| SMART Domains |
Protein: ENSMUSP00000063786
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
376 |
N/A |
INTRINSIC |
|
transmembrane domain
|
385 |
407 |
N/A |
INTRINSIC |
|
transmembrane domain
|
411 |
428 |
N/A |
INTRINSIC |
|
transmembrane domain
|
441 |
463 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
501 |
523 |
N/A |
INTRINSIC |
|
transmembrane domain
|
538 |
560 |
N/A |
INTRINSIC |
|
transmembrane domain
|
573 |
592 |
N/A |
INTRINSIC |
|
transmembrane domain
|
645 |
667 |
N/A |
INTRINSIC |
|
transmembrane domain
|
669 |
691 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1025 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1159 |
1389 |
7.5e-124 |
PFAM |
|
low complexity region
|
1462 |
1479 |
N/A |
INTRINSIC |
|
low complexity region
|
1481 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1538 |
N/A |
INTRINSIC |
|
low complexity region
|
1558 |
1569 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113615
|
| SMART Domains |
Protein: ENSMUSP00000109245
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
459 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
784 |
N/A |
INTRINSIC |
|
transmembrane domain
|
793 |
815 |
N/A |
INTRINSIC |
|
transmembrane domain
|
819 |
836 |
N/A |
INTRINSIC |
|
transmembrane domain
|
849 |
871 |
N/A |
INTRINSIC |
|
transmembrane domain
|
881 |
900 |
N/A |
INTRINSIC |
|
transmembrane domain
|
909 |
931 |
N/A |
INTRINSIC |
|
transmembrane domain
|
946 |
968 |
N/A |
INTRINSIC |
|
transmembrane domain
|
981 |
1000 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1053 |
1075 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1077 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1433 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1570 |
1796 |
5.9e-116 |
PFAM |
|
low complexity region
|
1870 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1918 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1946 |
N/A |
INTRINSIC |
|
low complexity region
|
1966 |
1977 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000127876
|
| SMART Domains |
Protein: ENSMUSP00000123696
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
69 |
75 |
N/A |
INTRINSIC |
|
transmembrane domain
|
84 |
106 |
N/A |
INTRINSIC |
|
transmembrane domain
|
110 |
127 |
N/A |
INTRINSIC |
|
transmembrane domain
|
140 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
172 |
191 |
N/A |
INTRINSIC |
|
transmembrane domain
|
200 |
222 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137313
|
| SMART Domains |
Protein: ENSMUSP00000115217
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
transmembrane domain
|
44 |
66 |
N/A |
INTRINSIC |
|
transmembrane domain
|
79 |
98 |
N/A |
INTRINSIC |
|
transmembrane domain
|
151 |
173 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141577
|
| SMART Domains |
Protein: ENSMUSP00000116451
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
110 |
N/A |
INTRINSIC |
|
transmembrane domain
|
119 |
141 |
N/A |
INTRINSIC |
|
transmembrane domain
|
145 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
175 |
197 |
N/A |
INTRINSIC |
|
transmembrane domain
|
207 |
224 |
N/A |
INTRINSIC |
|
transmembrane domain
|
229 |
251 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145270
|
| SMART Domains |
Protein: ENSMUSP00000116493
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
199 |
205 |
N/A |
INTRINSIC |
|
transmembrane domain
|
214 |
236 |
N/A |
INTRINSIC |
|
transmembrane domain
|
240 |
257 |
N/A |
INTRINSIC |
|
transmembrane domain
|
270 |
292 |
N/A |
INTRINSIC |
|
transmembrane domain
|
302 |
321 |
N/A |
INTRINSIC |
|
transmembrane domain
|
330 |
352 |
N/A |
INTRINSIC |
|
transmembrane domain
|
367 |
389 |
N/A |
INTRINSIC |
|
transmembrane domain
|
402 |
421 |
N/A |
INTRINSIC |
|
transmembrane domain
|
474 |
496 |
N/A |
INTRINSIC |
|
transmembrane domain
|
498 |
520 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146638
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147161
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000184789
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.8%
- 10x: 97.6%
- 20x: 95.9%
|
| Validation Efficiency |
100% (96/96) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl4 |
A |
T |
3: 95,586,918 (GRCm39) |
Y811N |
possibly damaging |
Het |
| Adrm1 |
T |
C |
2: 179,816,940 (GRCm39) |
|
probably benign |
Het |
| Alms1 |
T |
A |
6: 85,598,803 (GRCm39) |
S1210T |
probably benign |
Het |
| Ampd3 |
C |
T |
7: 110,377,015 (GRCm39) |
P11L |
probably damaging |
Het |
| Arhgap5 |
A |
G |
12: 52,563,290 (GRCm39) |
E87G |
possibly damaging |
Het |
| Armc5 |
C |
T |
7: 127,839,242 (GRCm39) |
|
probably benign |
Het |
| Asic2 |
C |
G |
11: 80,862,282 (GRCm39) |
|
probably benign |
Het |
| Asph |
A |
G |
4: 9,514,683 (GRCm39) |
|
probably benign |
Het |
| Bicd2 |
T |
A |
13: 49,531,351 (GRCm39) |
|
probably null |
Het |
| Brip1 |
A |
G |
11: 86,034,131 (GRCm39) |
L530P |
possibly damaging |
Het |
| Bsn |
G |
T |
9: 107,988,559 (GRCm39) |
|
probably benign |
Het |
| Btnl4 |
T |
A |
17: 34,688,608 (GRCm39) |
H390L |
probably benign |
Het |
| Ccdc70 |
A |
C |
8: 22,463,324 (GRCm39) |
K38T |
probably damaging |
Het |
| Ccni |
G |
A |
5: 93,350,175 (GRCm39) |
P35S |
probably benign |
Het |
| Cdh17 |
A |
G |
4: 11,810,451 (GRCm39) |
D714G |
possibly damaging |
Het |
| Cenpf |
A |
G |
1: 189,386,181 (GRCm39) |
L2033P |
probably damaging |
Het |
| Cfap69 |
A |
T |
5: 5,671,924 (GRCm39) |
M328K |
probably damaging |
Het |
| Cmah |
T |
G |
13: 24,601,193 (GRCm39) |
|
probably null |
Het |
| Cog6 |
T |
C |
3: 52,918,050 (GRCm39) |
T163A |
probably benign |
Het |
| Cyp2j8 |
G |
A |
4: 96,389,433 (GRCm39) |
S130F |
probably benign |
Het |
| Dgki |
A |
G |
6: 36,989,831 (GRCm39) |
V636A |
probably damaging |
Het |
| Dmkn |
T |
A |
7: 30,464,211 (GRCm39) |
|
probably benign |
Het |
| Dnah6 |
A |
G |
6: 73,012,276 (GRCm39) |
I3679T |
possibly damaging |
Het |
| Dsp |
A |
T |
13: 38,380,740 (GRCm39) |
Y2495F |
possibly damaging |
Het |
| Exosc4 |
C |
T |
15: 76,213,689 (GRCm39) |
A171V |
probably benign |
Het |
| Fbxw24 |
A |
G |
9: 109,452,577 (GRCm39) |
|
probably benign |
Het |
| Flvcr1 |
A |
T |
1: 190,757,779 (GRCm39) |
L171Q |
probably damaging |
Het |
| Fsd1 |
G |
T |
17: 56,303,445 (GRCm39) |
|
probably null |
Het |
| Gm7732 |
A |
G |
17: 21,350,106 (GRCm39) |
|
noncoding transcript |
Het |
| H2-K2 |
A |
C |
17: 34,194,597 (GRCm39) |
|
noncoding transcript |
Het |
| Hgf |
A |
G |
5: 16,798,857 (GRCm39) |
N295S |
probably damaging |
Het |
| Ift88 |
T |
A |
14: 57,754,870 (GRCm39) |
D811E |
probably benign |
Het |
| Igsf9b |
T |
A |
9: 27,234,657 (GRCm39) |
|
probably null |
Het |
| Immt |
T |
A |
6: 71,840,156 (GRCm39) |
V311E |
probably damaging |
Het |
| Ipo11 |
T |
A |
13: 107,056,119 (GRCm39) |
N51I |
possibly damaging |
Het |
| Isy1 |
T |
C |
6: 87,796,158 (GRCm39) |
K260E |
probably damaging |
Het |
| Jchain |
T |
G |
5: 88,674,061 (GRCm39) |
I28L |
probably benign |
Het |
| Jmjd1c |
T |
A |
10: 67,054,725 (GRCm39) |
|
probably null |
Het |
| Kif13b |
T |
C |
14: 64,989,111 (GRCm39) |
|
probably benign |
Het |
| Klhdc7b |
T |
C |
15: 89,272,372 (GRCm39) |
Y427H |
possibly damaging |
Het |
| Klhl8 |
T |
C |
5: 104,024,159 (GRCm39) |
|
probably benign |
Het |
| Lrp2 |
C |
T |
2: 69,341,292 (GRCm39) |
D963N |
probably damaging |
Het |
| Ltbp3 |
G |
T |
19: 5,796,776 (GRCm39) |
|
probably benign |
Het |
| Ltf |
C |
A |
9: 110,869,447 (GRCm39) |
Q41K |
probably benign |
Het |
| Med4 |
T |
A |
14: 73,754,097 (GRCm39) |
I148N |
probably damaging |
Het |
| Mlh3 |
T |
G |
12: 85,294,471 (GRCm39) |
S1242R |
possibly damaging |
Het |
| Mllt6 |
T |
C |
11: 97,567,185 (GRCm39) |
|
probably benign |
Het |
| Mpdz |
A |
G |
4: 81,210,710 (GRCm39) |
I1712T |
possibly damaging |
Het |
| Mrgprb4 |
T |
A |
7: 47,848,301 (GRCm39) |
H209L |
probably benign |
Het |
| Nkapl |
A |
T |
13: 21,652,610 (GRCm39) |
M1K |
probably null |
Het |
| Nmur2 |
T |
A |
11: 55,920,324 (GRCm39) |
|
probably benign |
Het |
| Nsun2 |
T |
A |
13: 69,691,816 (GRCm39) |
|
probably benign |
Het |
| Or10ag60 |
A |
G |
2: 87,438,271 (GRCm39) |
I180V |
probably benign |
Het |
| Or8k35 |
G |
A |
2: 86,424,425 (GRCm39) |
T249I |
probably benign |
Het |
| Ovgp1 |
T |
C |
3: 105,882,146 (GRCm39) |
|
probably benign |
Het |
| Pcdh8 |
A |
G |
14: 80,008,131 (GRCm39) |
V144A |
possibly damaging |
Het |
| Pla2r1 |
C |
A |
2: 60,309,874 (GRCm39) |
V570L |
possibly damaging |
Het |
| Plxnd1 |
C |
A |
6: 115,943,599 (GRCm39) |
E1202D |
possibly damaging |
Het |
| Ppp1r37 |
T |
C |
7: 19,266,179 (GRCm39) |
E529G |
probably benign |
Het |
| Prdm15 |
A |
G |
16: 97,613,833 (GRCm39) |
F496L |
possibly damaging |
Het |
| Prlhr |
G |
T |
19: 60,456,497 (GRCm39) |
S23* |
probably null |
Het |
| Prlhr |
A |
T |
19: 60,456,443 (GRCm39) |
V41D |
probably benign |
Het |
| Prpf4 |
C |
T |
4: 62,332,777 (GRCm39) |
|
probably benign |
Het |
| Psg26 |
C |
T |
7: 18,209,160 (GRCm39) |
R416H |
probably benign |
Het |
| Psg26 |
T |
C |
7: 18,212,212 (GRCm39) |
H381R |
probably benign |
Het |
| Ralgds |
T |
G |
2: 28,439,128 (GRCm39) |
M717R |
probably benign |
Het |
| Rbms1 |
T |
C |
2: 60,672,756 (GRCm39) |
N44D |
probably damaging |
Het |
| Rpa1 |
T |
C |
11: 75,209,227 (GRCm39) |
|
probably benign |
Het |
| Rprd2 |
T |
C |
3: 95,673,699 (GRCm39) |
N568S |
probably benign |
Het |
| Rptor |
A |
G |
11: 119,763,202 (GRCm39) |
M929V |
probably benign |
Het |
| Rspo1 |
T |
A |
4: 124,900,942 (GRCm39) |
C97S |
possibly damaging |
Het |
| Scin |
C |
T |
12: 40,129,606 (GRCm39) |
G396S |
probably damaging |
Het |
| Scn9a |
T |
C |
2: 66,377,456 (GRCm39) |
N409D |
probably damaging |
Het |
| Sf3b1 |
A |
G |
1: 55,058,544 (GRCm39) |
I15T |
probably damaging |
Het |
| Sh3bp2 |
T |
C |
5: 34,712,839 (GRCm39) |
V149A |
probably damaging |
Het |
| Slc39a12 |
T |
A |
2: 14,412,237 (GRCm39) |
|
probably benign |
Het |
| Sp9 |
G |
T |
2: 73,104,171 (GRCm39) |
A242S |
possibly damaging |
Het |
| Srr |
A |
G |
11: 74,801,891 (GRCm39) |
V126A |
possibly damaging |
Het |
| Tatdn3 |
G |
T |
1: 190,785,046 (GRCm39) |
|
probably benign |
Het |
| Tex14 |
G |
A |
11: 87,390,439 (GRCm39) |
V379I |
probably benign |
Het |
| Tmed6 |
T |
C |
8: 107,788,356 (GRCm39) |
N197S |
probably damaging |
Het |
| Ttbk2 |
A |
T |
2: 120,575,641 (GRCm39) |
I1043N |
probably benign |
Het |
| Ttbk2 |
G |
A |
2: 120,579,056 (GRCm39) |
L689F |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,641,040 (GRCm39) |
S5283P |
probably damaging |
Het |
| Ube3b |
C |
A |
5: 114,540,616 (GRCm39) |
S441* |
probably null |
Het |
| Ush2a |
G |
A |
1: 188,530,027 (GRCm39) |
C3272Y |
probably damaging |
Het |
| Vac14 |
T |
A |
8: 111,359,109 (GRCm39) |
I95K |
probably damaging |
Het |
| Vangl2 |
G |
A |
1: 171,833,784 (GRCm39) |
A433V |
probably damaging |
Het |
| Vwa5b1 |
A |
T |
4: 138,336,135 (GRCm39) |
V153D |
probably damaging |
Het |
| Zfhx3 |
T |
A |
8: 109,682,282 (GRCm39) |
D3240E |
unknown |
Het |
| Zfp945 |
A |
G |
17: 23,070,004 (GRCm39) |
C632R |
probably damaging |
Het |
| Zfyve26 |
G |
A |
12: 79,312,576 (GRCm39) |
|
probably benign |
Het |
| Zyg11b |
A |
T |
4: 108,099,273 (GRCm39) |
I606N |
possibly damaging |
Het |
|
| Other mutations in Pcnx3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01616:Pcnx3
|
APN |
19 |
5,717,287 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01667:Pcnx3
|
APN |
19 |
5,736,658 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01704:Pcnx3
|
APN |
19 |
5,717,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01752:Pcnx3
|
APN |
19 |
5,715,365 (GRCm39) |
nonsense |
probably null |
|
|
IGL01791:Pcnx3
|
APN |
19 |
5,723,295 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL01937:Pcnx3
|
APN |
19 |
5,727,691 (GRCm39) |
missense |
probably benign |
|
|
IGL01987:Pcnx3
|
APN |
19 |
5,727,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Pcnx3
|
APN |
19 |
5,729,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02417:Pcnx3
|
APN |
19 |
5,736,509 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03143:Pcnx3
|
APN |
19 |
5,735,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
buns
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
Pastries
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
pie
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7096_pcnx3_526
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
swirls
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
tip
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
PIT4453001:Pcnx3
|
UTSW |
19 |
5,722,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0360:Pcnx3
|
UTSW |
19 |
5,715,611 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0687:Pcnx3
|
UTSW |
19 |
5,734,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0840:Pcnx3
|
UTSW |
19 |
5,735,729 (GRCm39) |
splice site |
probably null |
|
|
R0907:Pcnx3
|
UTSW |
19 |
5,721,553 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1251:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1373:Pcnx3
|
UTSW |
19 |
5,715,544 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1572:Pcnx3
|
UTSW |
19 |
5,735,375 (GRCm39) |
nonsense |
probably null |
|
|
R1602:Pcnx3
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1628:Pcnx3
|
UTSW |
19 |
5,736,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1635:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1670:Pcnx3
|
UTSW |
19 |
5,723,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Pcnx3
|
UTSW |
19 |
5,722,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1898:Pcnx3
|
UTSW |
19 |
5,722,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Pcnx3
|
UTSW |
19 |
5,721,584 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2147:Pcnx3
|
UTSW |
19 |
5,717,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R2871:Pcnx3
|
UTSW |
19 |
5,733,774 (GRCm39) |
intron |
probably benign |
|
|
R3699:Pcnx3
|
UTSW |
19 |
5,722,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Pcnx3
|
UTSW |
19 |
5,728,696 (GRCm39) |
nonsense |
probably null |
|
|
R3856:Pcnx3
|
UTSW |
19 |
5,728,995 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3953:Pcnx3
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
R4613:Pcnx3
|
UTSW |
19 |
5,717,247 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4781:Pcnx3
|
UTSW |
19 |
5,737,158 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4816:Pcnx3
|
UTSW |
19 |
5,738,023 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Pcnx3
|
UTSW |
19 |
5,722,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Pcnx3
|
UTSW |
19 |
5,731,607 (GRCm39) |
intron |
probably benign |
|
|
R5950:Pcnx3
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5951:Pcnx3
|
UTSW |
19 |
5,721,708 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5969:Pcnx3
|
UTSW |
19 |
5,735,563 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6543:Pcnx3
|
UTSW |
19 |
5,715,275 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6704:Pcnx3
|
UTSW |
19 |
5,736,515 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7096:Pcnx3
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Pcnx3
|
UTSW |
19 |
5,737,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7308:Pcnx3
|
UTSW |
19 |
5,736,175 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7387:Pcnx3
|
UTSW |
19 |
5,723,364 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7488:Pcnx3
|
UTSW |
19 |
5,717,487 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7670:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7831:Pcnx3
|
UTSW |
19 |
5,735,989 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7850:Pcnx3
|
UTSW |
19 |
5,728,960 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8120:Pcnx3
|
UTSW |
19 |
5,717,574 (GRCm39) |
missense |
probably benign |
|
|
R8139:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8258:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8259:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8411:Pcnx3
|
UTSW |
19 |
5,729,618 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8429:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8431:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Pcnx3
|
UTSW |
19 |
5,736,670 (GRCm39) |
missense |
probably benign |
|
|
R8450:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Pcnx3
|
UTSW |
19 |
5,725,404 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8790:Pcnx3
|
UTSW |
19 |
5,735,206 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8939:Pcnx3
|
UTSW |
19 |
5,730,347 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9065:Pcnx3
|
UTSW |
19 |
5,717,582 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9070:Pcnx3
|
UTSW |
19 |
5,715,601 (GRCm39) |
missense |
probably benign |
0.33 |
|
X0028:Pcnx3
|
UTSW |
19 |
5,734,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0053:Pcnx3
|
UTSW |
19 |
5,736,650 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Pcnx3
|
UTSW |
19 |
5,737,248 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Pcnx3
|
UTSW |
19 |
5,721,654 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGCTGGAACCCCATACGCAC -3'
(R):5'- GCGACCCCACCGTTCTCTG -3'
Sequencing Primer
(F):5'- TACGCACACACCCTCATCAG -3'
(R):5'- TCCTTAAGTACATGACAGAATACCC -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation