Incidental Mutation 'R0724:Corin'
| ID |
63809 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Corin
|
| Ensembl Gene |
ENSMUSG00000005220 |
| Gene Name |
corin |
| Synonyms |
Lrp4 |
| MMRRC Submission |
038906-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.253)
|
| Stock # |
R0724 (G1)
|
| Quality Score |
109 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
72300025-72504473 bp(-) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 72332795 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135511
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000005352]
[ENSMUST00000167460]
[ENSMUST00000175766]
[ENSMUST00000176974]
[ENSMUST00000177290]
|
| AlphaFold |
Q9Z319 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000005352
|
| SMART Domains |
Protein: ENSMUSP00000005352
Gene: ENSMUSG00000005220
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
15 |
N/A |
INTRINSIC |
|
transmembrane domain
|
113 |
135 |
N/A |
INTRINSIC |
|
FRI
|
205 |
318 |
6.15e-11 |
SMART |
|
LDLa
|
336 |
372 |
1.31e-8 |
SMART |
|
LDLa
|
373 |
408 |
1.5e-8 |
SMART |
|
LDLa
|
409 |
447 |
5.47e-11 |
SMART |
|
LDLa
|
448 |
484 |
1.22e-8 |
SMART |
|
low complexity region
|
508 |
521 |
N/A |
INTRINSIC |
|
FRI
|
522 |
643 |
2.75e-31 |
SMART |
|
LDLa
|
647 |
684 |
2.19e-10 |
SMART |
|
LDLa
|
685 |
722 |
1.76e-5 |
SMART |
|
LDLa
|
723 |
759 |
4.18e-7 |
SMART |
|
SR
|
758 |
853 |
3.99e-10 |
SMART |
|
Tryp_SPc
|
868 |
1097 |
5.45e-76 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167460
|
| SMART Domains |
Protein: ENSMUSP00000127389
Gene: ENSMUSG00000005220
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
47 |
69 |
N/A |
INTRINSIC |
|
FRI
|
139 |
252 |
6.15e-11 |
SMART |
|
LDLa
|
270 |
306 |
1.31e-8 |
SMART |
|
LDLa
|
307 |
342 |
1.5e-8 |
SMART |
|
LDLa
|
343 |
381 |
5.47e-11 |
SMART |
|
LDLa
|
382 |
418 |
1.22e-8 |
SMART |
|
low complexity region
|
442 |
455 |
N/A |
INTRINSIC |
|
FRI
|
456 |
577 |
2.75e-31 |
SMART |
|
LDLa
|
581 |
618 |
2.19e-10 |
SMART |
|
LDLa
|
619 |
656 |
1.76e-5 |
SMART |
|
LDLa
|
657 |
693 |
4.18e-7 |
SMART |
|
SR
|
692 |
787 |
3.99e-10 |
SMART |
|
Tryp_SPc
|
802 |
1031 |
5.45e-76 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175766
|
| SMART Domains |
Protein: ENSMUSP00000135889
Gene: ENSMUSG00000005220
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
45 |
67 |
N/A |
INTRINSIC |
|
FRI
|
137 |
250 |
6.15e-11 |
SMART |
|
LDLa
|
268 |
304 |
1.31e-8 |
SMART |
|
LDLa
|
305 |
343 |
2.07e-11 |
SMART |
|
low complexity region
|
367 |
380 |
N/A |
INTRINSIC |
|
FRI
|
381 |
502 |
2.75e-31 |
SMART |
|
LDLa
|
506 |
543 |
2.19e-10 |
SMART |
|
LDLa
|
544 |
581 |
1.76e-5 |
SMART |
|
LDLa
|
582 |
618 |
4.18e-7 |
SMART |
|
SR
|
617 |
712 |
3.99e-10 |
SMART |
|
Tryp_SPc
|
727 |
956 |
5.45e-76 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176396
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176974
|
| SMART Domains |
Protein: ENSMUSP00000135722
Gene: ENSMUSG00000005220
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
47 |
69 |
N/A |
INTRINSIC |
|
FRI
|
139 |
252 |
6.15e-11 |
SMART |
|
LDLa
|
270 |
306 |
1.31e-8 |
SMART |
|
LDLa
|
307 |
344 |
3.86e-11 |
SMART |
|
LDLa
|
345 |
381 |
1.22e-8 |
SMART |
|
low complexity region
|
405 |
418 |
N/A |
INTRINSIC |
|
FRI
|
419 |
540 |
2.75e-31 |
SMART |
|
LDLa
|
544 |
581 |
2.19e-10 |
SMART |
|
LDLa
|
582 |
619 |
1.76e-5 |
SMART |
|
LDLa
|
620 |
656 |
4.18e-7 |
SMART |
|
SR
|
655 |
750 |
3.99e-10 |
SMART |
|
Tryp_SPc
|
765 |
994 |
5.45e-76 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177290
|
| SMART Domains |
Protein: ENSMUSP00000135511
Gene: ENSMUSG00000005220
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
47 |
69 |
N/A |
INTRINSIC |
|
FRI
|
72 |
185 |
6.15e-11 |
SMART |
|
LDLa
|
203 |
239 |
1.31e-8 |
SMART |
|
LDLa
|
240 |
275 |
1.5e-8 |
SMART |
|
LDLa
|
276 |
314 |
5.47e-11 |
SMART |
|
LDLa
|
315 |
351 |
1.22e-8 |
SMART |
|
low complexity region
|
375 |
388 |
N/A |
INTRINSIC |
|
FRI
|
389 |
510 |
2.75e-31 |
SMART |
|
LDLa
|
514 |
551 |
2.19e-10 |
SMART |
|
LDLa
|
552 |
589 |
1.76e-5 |
SMART |
|
LDLa
|
590 |
626 |
4.18e-7 |
SMART |
|
SR
|
625 |
720 |
3.99e-10 |
SMART |
|
Tryp_SPc
|
735 |
964 |
5.45e-76 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.9%
- 10x: 97.5%
- 20x: 95.2%
|
| Validation Efficiency |
100% (62/62) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
PHENOTYPE: Homozygous null mice display hypertension that is enhanced by high-salt diet and pregnancy, increased body weight, and cardiac hypertrophy. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 54 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700018F24Rik |
A |
G |
5: 145,044,763 (GRCm38) |
E136G |
probably benign |
Het |
| Adgre4 |
T |
A |
17: 55,852,281 (GRCm38) |
S655R |
probably benign |
Het |
| Ak7 |
T |
A |
12: 105,710,254 (GRCm38) |
V71E |
probably benign |
Het |
| Ank2 |
C |
T |
3: 126,962,337 (GRCm38) |
R1077H |
probably damaging |
Het |
| Anxa3 |
A |
G |
5: 96,828,748 (GRCm38) |
T198A |
possibly damaging |
Het |
| Atp1a1 |
A |
T |
3: 101,592,439 (GRCm38) |
I109N |
possibly damaging |
Het |
| Camta1 |
A |
G |
4: 151,077,892 (GRCm38) |
I119T |
probably damaging |
Het |
| Carm1 |
A |
G |
9: 21,587,374 (GRCm38) |
Y504C |
probably damaging |
Het |
| Casp1 |
C |
T |
9: 5,303,077 (GRCm38) |
P177L |
probably benign |
Het |
| Ccdc122 |
C |
A |
14: 77,092,077 (GRCm38) |
|
probably benign |
Het |
| Ces1a |
A |
G |
8: 93,039,513 (GRCm38) |
S158P |
probably damaging |
Het |
| Ces3a |
T |
A |
8: 105,050,195 (GRCm38) |
D103E |
possibly damaging |
Het |
| Clstn1 |
A |
C |
4: 149,643,624 (GRCm38) |
D583A |
possibly damaging |
Het |
| Cryba1 |
T |
C |
11: 77,719,457 (GRCm38) |
D144G |
probably damaging |
Het |
| Cwf19l2 |
G |
T |
9: 3,421,377 (GRCm38) |
|
probably null |
Het |
| Dis3l |
T |
C |
9: 64,307,126 (GRCm38) |
T1027A |
possibly damaging |
Het |
| Dopey2 |
A |
G |
16: 93,762,325 (GRCm38) |
E653G |
probably benign |
Het |
| Dst |
A |
G |
1: 34,188,677 (GRCm38) |
I1459V |
probably benign |
Het |
| Dyrk3 |
T |
C |
1: 131,130,140 (GRCm38) |
T64A |
probably benign |
Het |
| Emp2 |
C |
T |
16: 10,284,615 (GRCm38) |
C111Y |
probably benign |
Het |
| Enam |
A |
G |
5: 88,501,994 (GRCm38) |
Y454C |
probably damaging |
Het |
| Fbn1 |
A |
T |
2: 125,352,064 (GRCm38) |
C1328S |
probably benign |
Het |
| Gata3 |
T |
C |
2: 9,874,575 (GRCm38) |
T197A |
probably benign |
Het |
| Gm1043 |
A |
G |
5: 37,187,229 (GRCm38) |
T212A |
probably damaging |
Het |
| Gm15448 |
T |
C |
7: 3,816,872 (GRCm38) |
N564S |
possibly damaging |
Het |
| H2-Eb1 |
T |
C |
17: 34,315,032 (GRCm38) |
|
probably benign |
Het |
| Hand1 |
T |
C |
11: 57,831,680 (GRCm38) |
H36R |
probably damaging |
Het |
| Hmgcs2 |
C |
A |
3: 98,297,001 (GRCm38) |
Y239* |
probably null |
Het |
| Hoxc12 |
A |
G |
15: 102,937,055 (GRCm38) |
Y68C |
probably damaging |
Het |
| Inpp5a |
A |
G |
7: 139,516,663 (GRCm38) |
I143V |
probably benign |
Het |
| Klhdc2 |
C |
A |
12: 69,297,048 (GRCm38) |
F18L |
probably benign |
Het |
| Kpnb1 |
T |
C |
11: 97,178,304 (GRCm38) |
Y251C |
probably damaging |
Het |
| Lrch4 |
A |
T |
5: 137,637,308 (GRCm38) |
N315I |
probably damaging |
Het |
| Map3k10 |
A |
C |
7: 27,668,355 (GRCm38) |
V286G |
probably damaging |
Het |
| Myo7b |
G |
A |
18: 32,005,549 (GRCm38) |
|
probably benign |
Het |
| Nlrp2 |
G |
T |
7: 5,319,222 (GRCm38) |
L809I |
probably damaging |
Het |
| Oacyl |
T |
C |
18: 65,737,825 (GRCm38) |
|
probably benign |
Het |
| Olfr735 |
A |
G |
14: 50,345,917 (GRCm38) |
V175A |
possibly damaging |
Het |
| Paxbp1 |
T |
A |
16: 91,036,536 (GRCm38) |
D270V |
probably damaging |
Het |
| Pdia3 |
G |
A |
2: 121,432,377 (GRCm38) |
G275S |
probably damaging |
Het |
| Plcb3 |
G |
A |
19: 6,963,392 (GRCm38) |
R359C |
probably damaging |
Het |
| Plcxd3 |
G |
A |
15: 4,516,868 (GRCm38) |
S118N |
probably damaging |
Het |
| Ptpn14 |
T |
C |
1: 189,850,947 (GRCm38) |
S664P |
possibly damaging |
Het |
| Sirt1 |
T |
C |
10: 63,323,973 (GRCm38) |
I443V |
possibly damaging |
Het |
| Slc7a8 |
G |
A |
14: 54,735,186 (GRCm38) |
|
probably benign |
Het |
| Smim14 |
A |
G |
5: 65,453,339 (GRCm38) |
|
probably benign |
Het |
| Sost |
C |
T |
11: 101,966,918 (GRCm38) |
C19Y |
probably benign |
Het |
| Tcaf1 |
G |
T |
6: 42,675,367 (GRCm38) |
A727E |
probably damaging |
Het |
| Thoc1 |
T |
C |
18: 9,963,829 (GRCm38) |
L144P |
probably damaging |
Het |
| Tmem132b |
A |
T |
5: 125,783,421 (GRCm38) |
T577S |
possibly damaging |
Het |
| Tnfrsf21 |
C |
T |
17: 43,038,213 (GRCm38) |
H239Y |
probably benign |
Het |
| Tshr |
T |
C |
12: 91,538,286 (GRCm38) |
F666S |
probably damaging |
Het |
| Wdr1 |
A |
G |
5: 38,540,862 (GRCm38) |
V192A |
possibly damaging |
Het |
| Zfp697 |
T |
C |
3: 98,428,166 (GRCm38) |
W416R |
probably damaging |
Het |
|
| Other mutations in Corin |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00557:Corin
|
APN |
5 |
72,304,888 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01114:Corin
|
APN |
5 |
72,305,011 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01351:Corin
|
APN |
5 |
72,338,991 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01516:Corin
|
APN |
5 |
72,454,487 (GRCm38) |
nonsense |
probably null |
|
|
IGL01785:Corin
|
APN |
5 |
72,339,876 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01786:Corin
|
APN |
5 |
72,339,876 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01845:Corin
|
APN |
5 |
72,353,939 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02097:Corin
|
APN |
5 |
72,372,146 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02629:Corin
|
APN |
5 |
72,332,673 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03085:Corin
|
APN |
5 |
72,353,930 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03120:Corin
|
APN |
5 |
72,360,689 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03150:Corin
|
APN |
5 |
72,302,858 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03183:Corin
|
APN |
5 |
72,301,586 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL03185:Corin
|
APN |
5 |
72,332,781 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03408:Corin
|
APN |
5 |
72,342,961 (GRCm38) |
missense |
probably benign |
0.40 |
|
alpaca
|
UTSW |
5 |
72,503,952 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R0078:Corin
|
UTSW |
5 |
72,454,473 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R1065:Corin
|
UTSW |
5 |
72,301,650 (GRCm38) |
nonsense |
probably null |
|
|
R1301:Corin
|
UTSW |
5 |
72,304,933 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R1466:Corin
|
UTSW |
5 |
72,302,790 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1466:Corin
|
UTSW |
5 |
72,302,790 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1520:Corin
|
UTSW |
5 |
72,330,895 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1584:Corin
|
UTSW |
5 |
72,302,790 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1617:Corin
|
UTSW |
5 |
72,503,952 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1912:Corin
|
UTSW |
5 |
72,358,403 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2059:Corin
|
UTSW |
5 |
72,316,051 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R2173:Corin
|
UTSW |
5 |
72,504,079 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2242:Corin
|
UTSW |
5 |
72,332,711 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2373:Corin
|
UTSW |
5 |
72,339,038 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2850:Corin
|
UTSW |
5 |
72,304,955 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3683:Corin
|
UTSW |
5 |
72,330,855 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3684:Corin
|
UTSW |
5 |
72,330,855 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3790:Corin
|
UTSW |
5 |
72,435,298 (GRCm38) |
missense |
probably benign |
0.38 |
|
R3847:Corin
|
UTSW |
5 |
72,422,165 (GRCm38) |
missense |
probably benign |
0.13 |
|
R3926:Corin
|
UTSW |
5 |
72,372,130 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3939:Corin
|
UTSW |
5 |
72,339,879 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R3945:Corin
|
UTSW |
5 |
72,358,424 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4079:Corin
|
UTSW |
5 |
72,503,883 (GRCm38) |
missense |
probably benign |
0.03 |
|
R4224:Corin
|
UTSW |
5 |
72,343,108 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4473:Corin
|
UTSW |
5 |
72,339,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4585:Corin
|
UTSW |
5 |
72,329,699 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4586:Corin
|
UTSW |
5 |
72,329,699 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4849:Corin
|
UTSW |
5 |
72,302,835 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4926:Corin
|
UTSW |
5 |
72,372,182 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5080:Corin
|
UTSW |
5 |
72,353,851 (GRCm38) |
intron |
probably benign |
|
|
R5138:Corin
|
UTSW |
5 |
72,339,059 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5262:Corin
|
UTSW |
5 |
72,304,955 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5268:Corin
|
UTSW |
5 |
72,343,019 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5302:Corin
|
UTSW |
5 |
72,316,098 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5307:Corin
|
UTSW |
5 |
72,356,978 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5324:Corin
|
UTSW |
5 |
72,435,257 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5352:Corin
|
UTSW |
5 |
72,305,033 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5373:Corin
|
UTSW |
5 |
72,304,953 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5374:Corin
|
UTSW |
5 |
72,304,953 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5484:Corin
|
UTSW |
5 |
72,358,484 (GRCm38) |
missense |
probably benign |
0.15 |
|
R5502:Corin
|
UTSW |
5 |
72,316,106 (GRCm38) |
nonsense |
probably null |
|
|
R5544:Corin
|
UTSW |
5 |
72,305,014 (GRCm38) |
nonsense |
probably null |
|
|
R5682:Corin
|
UTSW |
5 |
72,422,154 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5818:Corin
|
UTSW |
5 |
72,435,395 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5992:Corin
|
UTSW |
5 |
72,316,389 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6115:Corin
|
UTSW |
5 |
72,360,729 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6181:Corin
|
UTSW |
5 |
72,372,096 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6317:Corin
|
UTSW |
5 |
72,339,045 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7053:Corin
|
UTSW |
5 |
72,301,527 (GRCm38) |
missense |
probably benign |
0.28 |
|
R7242:Corin
|
UTSW |
5 |
72,305,055 (GRCm38) |
missense |
probably benign |
0.14 |
|
R7452:Corin
|
UTSW |
5 |
72,435,247 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7783:Corin
|
UTSW |
5 |
72,301,624 (GRCm38) |
missense |
probably benign |
0.26 |
|
R7903:Corin
|
UTSW |
5 |
72,301,500 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7956:Corin
|
UTSW |
5 |
72,422,187 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8007:Corin
|
UTSW |
5 |
72,316,103 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8125:Corin
|
UTSW |
5 |
72,358,463 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8215:Corin
|
UTSW |
5 |
72,305,018 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8251:Corin
|
UTSW |
5 |
72,356,926 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8364:Corin
|
UTSW |
5 |
72,304,931 (GRCm38) |
missense |
probably benign |
|
|
R8505:Corin
|
UTSW |
5 |
72,435,407 (GRCm38) |
missense |
probably benign |
0.21 |
|
R8746:Corin
|
UTSW |
5 |
72,435,352 (GRCm38) |
missense |
probably benign |
0.31 |
|
R8887:Corin
|
UTSW |
5 |
72,329,610 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9484:Corin
|
UTSW |
5 |
72,339,937 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9640:Corin
|
UTSW |
5 |
72,435,254 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Corin
|
UTSW |
5 |
72,454,493 (GRCm38) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGAACCCAGATCAAATAACTCAGGAGTG -3'
(R):5'- CAGAATGGAGACTGCCGTGAGC -3'
Sequencing Primer
(F):5'- CATTTTGGATACTAGCATGAGGTC -3'
(R):5'- GCTCCTACTTTCAGAATCACACG -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation