Incidental Mutation 'R8296:Rnf123'
| ID |
638954 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rnf123
|
| Ensembl Gene |
ENSMUSG00000041528 |
| Gene Name |
ring finger protein 123 |
| Synonyms |
KPC1 |
| MMRRC Submission |
067785-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.171)
|
| Stock # |
R8296 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
107928869-107957183 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 107940089 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Aspartic acid
at position 768
(V768D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125745
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047746]
[ENSMUST00000160249]
[ENSMUST00000160649]
[ENSMUST00000162355]
[ENSMUST00000162753]
[ENSMUST00000178267]
|
| AlphaFold |
Q5XPI3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047746
AA Change: V768D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000040803
Gene: ENSMUSG00000041528
AA Change: V768D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159306
|
| SMART Domains |
Protein: ENSMUSP00000125695
Gene: ENSMUSG00000041528
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
172 |
192 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160249
AA Change: V762D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000124548
Gene: ENSMUSG00000041528
AA Change: V762D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160649
AA Change: V762D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000125495
Gene: ENSMUSG00000041528
AA Change: V762D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162355
AA Change: V768D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000125745
Gene: ENSMUSG00000041528
AA Change: V768D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162753
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000178267
AA Change: V762D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000136953
Gene: ENSMUSG00000041528
AA Change: V762D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
100% (77/77) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
T |
A |
13: 77,415,896 (GRCm39) |
L663Q |
probably damaging |
Het |
| 2610008E11Rik |
C |
G |
10: 78,903,568 (GRCm39) |
R249S |
probably benign |
Het |
| 6030469F06Rik |
A |
G |
12: 31,235,058 (GRCm39) |
N146S |
noncoding transcript |
Het |
| Abcb5 |
G |
A |
12: 118,838,467 (GRCm39) |
P1032S |
probably benign |
Het |
| Acvr2a |
A |
T |
2: 48,789,736 (GRCm39) |
D493V |
possibly damaging |
Het |
| Amacr |
A |
G |
15: 10,995,004 (GRCm39) |
D272G |
probably benign |
Het |
| Bach1 |
A |
C |
16: 87,526,467 (GRCm39) |
K643T |
probably damaging |
Het |
| Bmt2 |
T |
C |
6: 13,628,672 (GRCm39) |
Y337C |
probably damaging |
Het |
| Bsn |
A |
G |
9: 107,994,578 (GRCm39) |
S566P |
probably benign |
Het |
| Cass4 |
A |
C |
2: 172,269,094 (GRCm39) |
D392A |
probably benign |
Het |
| Cbx2 |
A |
G |
11: 118,918,954 (GRCm39) |
E173G |
probably damaging |
Het |
| Ccdc166 |
G |
C |
15: 75,852,860 (GRCm39) |
A369G |
probably benign |
Het |
| Ccdc77 |
G |
A |
6: 120,308,870 (GRCm39) |
T315M |
possibly damaging |
Het |
| Ceacam10 |
C |
A |
7: 24,480,513 (GRCm39) |
H215N |
unknown |
Het |
| Ces1e |
C |
T |
8: 93,929,947 (GRCm39) |
M445I |
probably benign |
Het |
| Ces2b |
T |
G |
8: 105,563,112 (GRCm39) |
V350G |
possibly damaging |
Het |
| Chtf18 |
A |
G |
17: 25,941,165 (GRCm39) |
L611P |
probably benign |
Het |
| Col9a1 |
C |
A |
1: 24,217,380 (GRCm39) |
P19T |
unknown |
Het |
| Csf1r |
A |
T |
18: 61,250,750 (GRCm39) |
N487I |
probably damaging |
Het |
| Csl |
A |
T |
10: 99,594,161 (GRCm39) |
H301Q |
probably damaging |
Het |
| Cyp24a1 |
G |
A |
2: 170,332,036 (GRCm39) |
T330M |
probably damaging |
Het |
| Ddb2 |
T |
C |
2: 91,042,645 (GRCm39) |
D405G |
probably damaging |
Het |
| Degs1 |
A |
G |
1: 182,110,241 (GRCm39) |
F10L |
probably benign |
Het |
| Dhrs2 |
T |
A |
14: 55,477,928 (GRCm39) |
I220N |
probably damaging |
Het |
| Dlg5 |
T |
C |
14: 24,198,328 (GRCm39) |
D1535G |
possibly damaging |
Het |
| Dpy19l1 |
A |
G |
9: 24,414,372 (GRCm39) |
S19P |
probably benign |
Het |
| Eif3l |
A |
C |
15: 78,963,220 (GRCm39) |
E134A |
possibly damaging |
Het |
| Epb41 |
C |
A |
4: 131,664,772 (GRCm39) |
V90L |
|
Het |
| Flad1 |
A |
T |
3: 89,316,109 (GRCm39) |
V151D |
probably damaging |
Het |
| Gja10 |
A |
T |
4: 32,601,568 (GRCm39) |
I272N |
probably benign |
Het |
| Glmp |
T |
A |
3: 88,233,580 (GRCm39) |
D178E |
probably benign |
Het |
| Gm16494 |
G |
A |
17: 47,327,750 (GRCm39) |
P45S |
probably damaging |
Het |
| Gm4553 |
T |
C |
7: 141,719,458 (GRCm39) |
D6G |
unknown |
Het |
| Grid2 |
G |
A |
6: 63,233,929 (GRCm39) |
|
probably null |
Het |
| Icmt |
A |
G |
4: 152,387,482 (GRCm39) |
M226V |
probably benign |
Het |
| Igkv5-39 |
T |
C |
6: 69,877,607 (GRCm39) |
S50G |
probably benign |
Het |
| Ints5 |
T |
C |
19: 8,872,484 (GRCm39) |
S148P |
probably damaging |
Het |
| Itga2b |
A |
C |
11: 102,351,985 (GRCm39) |
V504G |
possibly damaging |
Het |
| Krt20 |
T |
A |
11: 99,323,063 (GRCm39) |
Y253F |
probably damaging |
Het |
| Man2a2 |
T |
A |
7: 80,018,656 (GRCm39) |
I68L |
probably damaging |
Het |
| Mpi |
G |
A |
9: 57,455,954 (GRCm39) |
T176I |
probably benign |
Het |
| Msh6 |
C |
T |
17: 88,294,340 (GRCm39) |
R1032C |
probably damaging |
Het |
| Myot |
C |
T |
18: 44,475,416 (GRCm39) |
T179I |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,116,601 (GRCm39) |
S946P |
|
Het |
| Notch3 |
G |
A |
17: 32,341,713 (GRCm39) |
A2013V |
probably damaging |
Het |
| Nr1d1 |
T |
C |
11: 98,662,133 (GRCm39) |
Y167C |
probably damaging |
Het |
| Or52h7 |
T |
A |
7: 104,213,593 (GRCm39) |
F55Y |
probably benign |
Het |
| Or52n2c |
T |
C |
7: 104,574,828 (GRCm39) |
I48V |
probably benign |
Het |
| Or7g32 |
A |
G |
9: 19,408,377 (GRCm39) |
E111G |
probably damaging |
Het |
| Or8k40 |
A |
C |
2: 86,584,893 (GRCm39) |
L63R |
probably damaging |
Het |
| P4ha3 |
G |
A |
7: 99,966,309 (GRCm39) |
V485M |
probably damaging |
Het |
| Pbk |
T |
A |
14: 66,054,185 (GRCm39) |
C243* |
probably null |
Het |
| Pde4b |
T |
A |
4: 102,459,983 (GRCm39) |
L388H |
possibly damaging |
Het |
| Pecam1 |
T |
C |
11: 106,579,745 (GRCm39) |
D439G |
probably benign |
Het |
| Pknox2 |
A |
T |
9: 36,822,459 (GRCm39) |
M230K |
probably benign |
Het |
| Plekhh2 |
A |
G |
17: 84,908,113 (GRCm39) |
I1185V |
probably damaging |
Het |
| Polr3g |
A |
G |
13: 81,842,682 (GRCm39) |
V111A |
unknown |
Het |
| Prkcg |
G |
C |
7: 3,377,580 (GRCm39) |
E562D |
probably benign |
Het |
| Rftn1 |
G |
T |
17: 50,354,408 (GRCm39) |
A318D |
probably damaging |
Het |
| Rps16 |
T |
A |
7: 28,052,008 (GRCm39) |
S129T |
probably benign |
Het |
| Scg2 |
A |
T |
1: 79,413,222 (GRCm39) |
N460K |
probably benign |
Het |
| Sct |
T |
C |
7: 140,858,807 (GRCm39) |
S42G |
probably damaging |
Het |
| Spef2 |
A |
T |
15: 9,727,629 (GRCm39) |
N151K |
probably benign |
Het |
| Syce1l |
C |
A |
8: 114,380,721 (GRCm39) |
D144E |
possibly damaging |
Het |
| Syt17 |
T |
C |
7: 118,036,069 (GRCm39) |
Y99C |
probably damaging |
Het |
| Tgfbr3 |
T |
C |
5: 107,287,640 (GRCm39) |
N520D |
probably damaging |
Het |
| Thsd7b |
A |
G |
1: 129,523,193 (GRCm39) |
S76G |
probably benign |
Het |
| Tmem63a |
G |
T |
1: 180,788,685 (GRCm39) |
V341F |
probably benign |
Het |
| Trim5 |
A |
G |
7: 103,914,993 (GRCm39) |
S359P |
probably damaging |
Het |
| Tst |
A |
T |
15: 78,284,020 (GRCm39) |
V269E |
probably damaging |
Het |
| Ubr3 |
A |
T |
2: 69,784,706 (GRCm39) |
I808F |
probably null |
Het |
| Ugt3a1 |
T |
A |
15: 9,362,024 (GRCm39) |
Y267N |
probably benign |
Het |
| Wwc1 |
A |
T |
11: 35,761,384 (GRCm39) |
|
probably benign |
Het |
| Zfp36l2 |
G |
T |
17: 84,494,552 (GRCm39) |
N28K |
probably damaging |
Het |
| Zfp57 |
A |
G |
17: 37,321,136 (GRCm39) |
D330G |
probably benign |
Het |
| Zgrf1 |
C |
A |
3: 127,377,644 (GRCm39) |
S963Y |
probably damaging |
Het |
| Zranb2 |
A |
G |
3: 157,247,412 (GRCm39) |
K197E |
unknown |
Het |
|
| Other mutations in Rnf123 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00950:Rnf123
|
APN |
9 |
107,944,594 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01358:Rnf123
|
APN |
9 |
107,946,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01464:Rnf123
|
APN |
9 |
107,929,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01637:Rnf123
|
APN |
9 |
107,935,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01669:Rnf123
|
APN |
9 |
107,935,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01905:Rnf123
|
APN |
9 |
107,948,569 (GRCm39) |
splice site |
probably benign |
|
|
IGL02070:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02072:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02073:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02074:Rnf123
|
APN |
9 |
107,944,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02079:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02080:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02231:Rnf123
|
APN |
9 |
107,943,598 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02281:Rnf123
|
APN |
9 |
107,948,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02336:Rnf123
|
APN |
9 |
107,939,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Rnf123
|
APN |
9 |
107,943,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02565:Rnf123
|
APN |
9 |
107,929,411 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02571:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02572:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02574:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02586:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02589:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02600:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02601:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02602:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02603:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02609:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02628:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02629:Rnf123
|
APN |
9 |
107,947,988 (GRCm39) |
splice site |
probably benign |
|
|
IGL02629:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02630:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02631:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02632:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02650:Rnf123
|
APN |
9 |
107,946,947 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02690:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02691:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02692:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02693:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02713:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02736:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02929:Rnf123
|
APN |
9 |
107,946,275 (GRCm39) |
missense |
probably benign |
|
|
R1175:Rnf123
|
UTSW |
9 |
107,954,572 (GRCm39) |
missense |
probably benign |
|
|
R1465:Rnf123
|
UTSW |
9 |
107,948,665 (GRCm39) |
splice site |
probably benign |
|
|
R1502:Rnf123
|
UTSW |
9 |
107,945,709 (GRCm39) |
splice site |
probably null |
|
|
R1682:Rnf123
|
UTSW |
9 |
107,954,597 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1817:Rnf123
|
UTSW |
9 |
107,940,125 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1855:Rnf123
|
UTSW |
9 |
107,938,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2394:Rnf123
|
UTSW |
9 |
107,940,735 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Rnf123
|
UTSW |
9 |
107,940,720 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3896:Rnf123
|
UTSW |
9 |
107,946,302 (GRCm39) |
splice site |
probably benign |
|
|
R3940:Rnf123
|
UTSW |
9 |
107,941,234 (GRCm39) |
splice site |
probably benign |
|
|
R4206:Rnf123
|
UTSW |
9 |
107,941,162 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4641:Rnf123
|
UTSW |
9 |
107,935,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4714:Rnf123
|
UTSW |
9 |
107,929,638 (GRCm39) |
splice site |
probably null |
|
|
R4767:Rnf123
|
UTSW |
9 |
107,929,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4849:Rnf123
|
UTSW |
9 |
107,933,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4899:Rnf123
|
UTSW |
9 |
107,940,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5274:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5275:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5276:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5294:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5295:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5394:Rnf123
|
UTSW |
9 |
107,947,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5717:Rnf123
|
UTSW |
9 |
107,944,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6186:Rnf123
|
UTSW |
9 |
107,947,157 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6449:Rnf123
|
UTSW |
9 |
107,933,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6502:Rnf123
|
UTSW |
9 |
107,945,531 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6944:Rnf123
|
UTSW |
9 |
107,940,822 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7003:Rnf123
|
UTSW |
9 |
107,940,882 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7088:Rnf123
|
UTSW |
9 |
107,935,735 (GRCm39) |
missense |
probably null |
1.00 |
|
R7092:Rnf123
|
UTSW |
9 |
107,945,799 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7100:Rnf123
|
UTSW |
9 |
107,933,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7257:Rnf123
|
UTSW |
9 |
107,946,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7453:Rnf123
|
UTSW |
9 |
107,947,607 (GRCm39) |
splice site |
probably null |
|
|
R7468:Rnf123
|
UTSW |
9 |
107,946,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7517:Rnf123
|
UTSW |
9 |
107,947,473 (GRCm39) |
nonsense |
probably null |
|
|
R7577:Rnf123
|
UTSW |
9 |
107,947,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8322:Rnf123
|
UTSW |
9 |
107,945,706 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8754:Rnf123
|
UTSW |
9 |
107,948,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8783:Rnf123
|
UTSW |
9 |
107,946,272 (GRCm39) |
missense |
probably benign |
|
|
R9052:Rnf123
|
UTSW |
9 |
107,936,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9156:Rnf123
|
UTSW |
9 |
107,940,227 (GRCm39) |
splice site |
probably benign |
|
|
R9170:Rnf123
|
UTSW |
9 |
107,948,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Rnf123
|
UTSW |
9 |
107,944,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9385:Rnf123
|
UTSW |
9 |
107,929,467 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9394:Rnf123
|
UTSW |
9 |
107,942,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9432:Rnf123
|
UTSW |
9 |
107,937,008 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9717:Rnf123
|
UTSW |
9 |
107,954,963 (GRCm39) |
missense |
probably benign |
0.43 |
|
Z1176:Rnf123
|
UTSW |
9 |
107,940,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Rnf123
|
UTSW |
9 |
107,935,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAACCTAGTCTGGACCCAGC -3'
(R):5'- CCAGGAGCTTGTGAATATTTAAGAG -3'
Sequencing Primer
(F):5'- GCCTGCAAAGTTCCCAAAATTG -3'
(R):5'- TTAAGGTCAGCCAGGTCTGCATAC -3'
|
| Posted On |
2020-07-28 |
Incidental Mutation