|Institutional Source||Beutler Lab|
|Gene Name||ATP-binding cassette, sub-family F (GCN20), member 2|
|Is this an essential gene?||Probably non essential (E-score: 0.246)|
|Stock #||R8266 (G1)|
|Chromosomal Location||24565345-24577467 bp(-) (GRCm38)|
|Type of Mutation||small insertion (1 aa in frame mutation)|
|DNA Base Change (assembly)||CAT to CATAAT at 24576591 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000030795 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000030795]|
|Predicted Effect||probably benign
|Coding Region Coverage||
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding casette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Jul 2013]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Abcf2||
(F):5'- TGTCTACTGCAGCACCAACC -3'
(R):5'- GGATGGGATAGCACTCAGAC -3'
(F):5'- GGTGTCACCAAAAAGTTTCATGGC -3'
(R):5'- GGATAGCACTCAGACATTCTTACCTG -3'