Incidental Mutation 'R8260:Med13l'
| ID |
639987 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Med13l
|
| Ensembl Gene |
ENSMUSG00000018076 |
| Gene Name |
mediator complex subunit 13-like |
| Synonyms |
9030618F05Rik, Trap240L, 6330591G05Rik, Thrap2, 2210413I17Rik |
| MMRRC Submission |
067685-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.968)
|
| Stock # |
R8260 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
118698744-118903503 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 118886794 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 1565
(T1565I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000098379
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100816]
[ENSMUST00000201010]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100816
AA Change: T1565I
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000098379
Gene: ENSMUSG00000018076
AA Change: T1565I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
2.5e-116 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2197 |
1e-142 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000201010
AA Change: T1565I
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000144092
Gene: ENSMUSG00000018076
AA Change: T1565I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
1e-112 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2206 |
1.7e-138 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930578I06Rik |
G |
C |
14: 64,223,633 (GRCm39) |
L48V |
probably benign |
Het |
| Acbd3 |
T |
C |
1: 180,566,095 (GRCm39) |
Y263H |
probably damaging |
Het |
| Acot4 |
C |
A |
12: 84,088,809 (GRCm39) |
P219Q |
possibly damaging |
Het |
| Adcy6 |
A |
G |
15: 98,498,919 (GRCm39) |
F294S |
probably damaging |
Het |
| Ahcyl |
T |
C |
16: 45,974,786 (GRCm39) |
E197G |
probably damaging |
Het |
| Aplf |
T |
C |
6: 87,606,987 (GRCm39) |
R476G |
probably benign |
Het |
| Arid1b |
A |
G |
17: 5,382,788 (GRCm39) |
T1292A |
probably benign |
Het |
| Atp2c1 |
T |
A |
9: 105,295,778 (GRCm39) |
I649F |
probably damaging |
Het |
| Bbs10 |
C |
T |
10: 111,136,104 (GRCm39) |
Q406* |
probably null |
Het |
| Bcas3 |
T |
A |
11: 85,400,372 (GRCm39) |
M447K |
possibly damaging |
Het |
| Bmal1 |
A |
T |
7: 112,884,258 (GRCm39) |
I92F |
probably damaging |
Het |
| Cars1 |
T |
C |
7: 143,139,446 (GRCm39) |
D214G |
probably benign |
Het |
| Ccdc88a |
A |
T |
11: 29,443,934 (GRCm39) |
I1410F |
probably benign |
Het |
| Cd55b |
A |
T |
1: 130,316,415 (GRCm39) |
L378H |
probably damaging |
Het |
| Cdh1 |
G |
A |
8: 107,330,979 (GRCm39) |
E37K |
probably benign |
Het |
| Cep72 |
T |
C |
13: 74,206,465 (GRCm39) |
Y119C |
probably damaging |
Het |
| Ctnnd2 |
A |
G |
15: 30,634,879 (GRCm39) |
T176A |
possibly damaging |
Het |
| D630045J12Rik |
T |
A |
6: 38,119,846 (GRCm39) |
|
probably null |
Het |
| Ddi1 |
A |
T |
9: 6,265,524 (GRCm39) |
C282S |
probably damaging |
Het |
| Ddit4 |
T |
C |
10: 59,787,277 (GRCm39) |
T20A |
probably benign |
Het |
| Dpp10 |
T |
A |
1: 123,614,024 (GRCm39) |
T102S |
probably benign |
Het |
| Ep400 |
T |
A |
5: 110,903,478 (GRCm39) |
K374* |
probably null |
Het |
| Epha3 |
A |
G |
16: 63,403,917 (GRCm39) |
L728P |
probably damaging |
Het |
| Fbxw21 |
C |
A |
9: 108,975,614 (GRCm39) |
|
probably null |
Het |
| Frmpd1 |
A |
G |
4: 45,244,638 (GRCm39) |
E109G |
probably damaging |
Het |
| Ggt1 |
C |
T |
10: 75,417,245 (GRCm39) |
P332L |
probably damaging |
Het |
| Gm4779 |
G |
C |
X: 100,837,390 (GRCm39) |
T171S |
possibly damaging |
Het |
| Gm5431 |
A |
T |
11: 48,785,556 (GRCm39) |
I273K |
probably benign |
Het |
| Gon4l |
A |
G |
3: 88,799,937 (GRCm39) |
N861D |
probably damaging |
Het |
| Grm5 |
T |
C |
7: 87,724,340 (GRCm39) |
|
probably null |
Het |
| Helt |
T |
C |
8: 46,745,745 (GRCm39) |
N84S |
possibly damaging |
Het |
| Hnrnpa0 |
G |
T |
13: 58,275,228 (GRCm39) |
Y300* |
probably null |
Het |
| Ints1 |
T |
C |
5: 139,750,968 (GRCm39) |
T810A |
|
Het |
| Irf2bp1 |
C |
T |
7: 18,740,079 (GRCm39) |
A573V |
possibly damaging |
Het |
| Itgbl1 |
C |
A |
14: 124,065,246 (GRCm39) |
D133E |
probably benign |
Het |
| Kctd15 |
A |
G |
7: 34,344,267 (GRCm39) |
F128S |
possibly damaging |
Het |
| Klra17 |
T |
A |
6: 129,808,421 (GRCm39) |
N271Y |
probably damaging |
Het |
| Kmt2c |
T |
A |
5: 25,610,514 (GRCm39) |
E197D |
possibly damaging |
Het |
| Larp1 |
C |
A |
11: 57,949,515 (GRCm39) |
T1048K |
probably benign |
Het |
| Macf1 |
A |
G |
4: 123,365,863 (GRCm39) |
V2966A |
probably benign |
Het |
| Magi3 |
A |
G |
3: 103,922,625 (GRCm39) |
L1364P |
probably benign |
Het |
| Malrd1 |
T |
C |
2: 15,619,017 (GRCm39) |
S294P |
|
Het |
| Mov10l1 |
A |
G |
15: 88,896,313 (GRCm39) |
D719G |
probably benign |
Het |
| Mtcl3 |
T |
A |
10: 29,024,270 (GRCm39) |
H395Q |
possibly damaging |
Het |
| Muc4 |
CAC |
CACTAC |
16: 32,575,367 (GRCm39) |
|
probably benign |
Het |
| Myh14 |
T |
C |
7: 44,264,800 (GRCm39) |
E1654G |
probably damaging |
Het |
| Myo1c |
C |
T |
11: 75,546,942 (GRCm39) |
|
probably benign |
Het |
| Myo9a |
A |
G |
9: 59,817,961 (GRCm39) |
T2343A |
probably benign |
Het |
| Or1j12 |
A |
G |
2: 36,342,897 (GRCm39) |
Q100R |
probably damaging |
Het |
| Or2ag18 |
A |
T |
7: 106,405,234 (GRCm39) |
V145E |
possibly damaging |
Het |
| Or2d2b |
A |
T |
7: 106,706,062 (GRCm39) |
M2K |
probably benign |
Het |
| Or4m1 |
T |
C |
14: 50,557,615 (GRCm39) |
K226E |
probably benign |
Het |
| Or52m2 |
T |
A |
7: 102,263,432 (GRCm39) |
I255F |
possibly damaging |
Het |
| Or52n5 |
T |
A |
7: 104,587,879 (GRCm39) |
Y49N |
probably damaging |
Het |
| Or6c2 |
T |
A |
10: 129,362,957 (GRCm39) |
I287N |
possibly damaging |
Het |
| Or8k53 |
T |
A |
2: 86,177,276 (GRCm39) |
Y278F |
possibly damaging |
Het |
| Or9g3 |
A |
T |
2: 85,589,820 (GRCm39) |
L300Q |
probably damaging |
Het |
| Osmr |
A |
T |
15: 6,844,897 (GRCm39) |
D957E |
probably benign |
Het |
| Pappa |
T |
A |
4: 65,234,419 (GRCm39) |
V1408E |
probably damaging |
Het |
| Pcnx3 |
C |
T |
19: 5,715,412 (GRCm39) |
G1946E |
probably damaging |
Het |
| Pdcd6ip |
A |
T |
9: 113,501,865 (GRCm39) |
D464E |
probably benign |
Het |
| Pde1c |
T |
C |
6: 56,114,404 (GRCm39) |
Y503C |
probably benign |
Het |
| Potefam3d |
A |
T |
8: 69,972,400 (GRCm39) |
D116E |
possibly damaging |
Het |
| Prob1 |
T |
A |
18: 35,787,210 (GRCm39) |
E348V |
possibly damaging |
Het |
| Rnls |
A |
G |
19: 33,180,048 (GRCm39) |
L134S |
probably damaging |
Het |
| Scrn3 |
T |
C |
2: 73,166,202 (GRCm39) |
Y412H |
probably damaging |
Het |
| Serpina3g |
T |
C |
12: 104,205,362 (GRCm39) |
S34P |
probably benign |
Het |
| Sertad3 |
G |
A |
7: 27,175,784 (GRCm39) |
A73T |
probably benign |
Het |
| Sez6l |
C |
T |
5: 112,609,122 (GRCm39) |
A576T |
probably benign |
Het |
| Sh3tc2 |
G |
A |
18: 62,146,137 (GRCm39) |
R1172H |
probably damaging |
Het |
| Sirt3 |
A |
G |
7: 140,456,319 (GRCm39) |
V110A |
|
Het |
| Smpd3 |
A |
T |
8: 106,984,047 (GRCm39) |
D557E |
probably benign |
Het |
| Sptssb |
A |
T |
3: 69,728,305 (GRCm39) |
M44K |
probably damaging |
Het |
| Tars2 |
A |
G |
3: 95,662,132 (GRCm39) |
W7R |
probably damaging |
Het |
| Tbc1d9b |
A |
G |
11: 50,055,013 (GRCm39) |
D964G |
probably benign |
Het |
| Tiam2 |
A |
T |
17: 3,568,594 (GRCm39) |
D1580V |
possibly damaging |
Het |
| Tmeff2 |
T |
A |
1: 50,977,478 (GRCm39) |
V130D |
probably damaging |
Het |
| Top2a |
T |
A |
11: 98,891,595 (GRCm39) |
E1176V |
probably null |
Het |
| Trappc9 |
C |
A |
15: 72,813,758 (GRCm39) |
E680* |
probably null |
Het |
| Trip10 |
A |
G |
17: 57,564,314 (GRCm39) |
N355S |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,596,337 (GRCm39) |
E20192G |
probably damaging |
Het |
| Vmn2r96 |
A |
G |
17: 18,804,243 (GRCm39) |
M306V |
probably benign |
Het |
| Wdr90 |
A |
T |
17: 26,064,141 (GRCm39) |
H1860Q |
probably damaging |
Het |
| Wrnip1 |
A |
G |
13: 32,989,339 (GRCm39) |
I276V |
possibly damaging |
Het |
| Zfp608 |
T |
C |
18: 55,030,821 (GRCm39) |
K1040E |
possibly damaging |
Het |
| Zfp808 |
T |
A |
13: 62,320,552 (GRCm39) |
C594S |
probably benign |
Het |
|
| Other mutations in Med13l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Med13l
|
APN |
5 |
118,862,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01012:Med13l
|
APN |
5 |
118,872,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01316:Med13l
|
APN |
5 |
118,900,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01529:Med13l
|
APN |
5 |
118,880,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01731:Med13l
|
APN |
5 |
118,880,472 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01790:Med13l
|
APN |
5 |
118,731,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02394:Med13l
|
APN |
5 |
118,886,898 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL02432:Med13l
|
APN |
5 |
118,876,465 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02698:Med13l
|
APN |
5 |
118,900,894 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02801:Med13l
|
APN |
5 |
118,883,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03242:Med13l
|
APN |
5 |
118,885,510 (GRCm39) |
missense |
probably benign |
|
|
IGL03270:Med13l
|
APN |
5 |
118,869,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Basics
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
firmament
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
Fundament
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Root
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0035:Med13l
|
UTSW |
5 |
118,880,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0136:Med13l
|
UTSW |
5 |
118,862,115 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0158:Med13l
|
UTSW |
5 |
118,880,514 (GRCm39) |
missense |
unknown |
|
|
R0197:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0370:Med13l
|
UTSW |
5 |
118,879,891 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0492:Med13l
|
UTSW |
5 |
118,876,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Med13l
|
UTSW |
5 |
118,897,188 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0726:Med13l
|
UTSW |
5 |
118,886,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0738:Med13l
|
UTSW |
5 |
118,889,698 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0827:Med13l
|
UTSW |
5 |
118,864,312 (GRCm39) |
splice site |
probably benign |
|
|
R0883:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0959:Med13l
|
UTSW |
5 |
118,892,350 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1458:Med13l
|
UTSW |
5 |
118,876,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1562:Med13l
|
UTSW |
5 |
118,876,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1577:Med13l
|
UTSW |
5 |
118,859,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1661:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1665:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Med13l
|
UTSW |
5 |
118,880,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1929:Med13l
|
UTSW |
5 |
118,866,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1967:Med13l
|
UTSW |
5 |
118,899,387 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2301:Med13l
|
UTSW |
5 |
118,731,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3691:Med13l
|
UTSW |
5 |
118,859,562 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3895:Med13l
|
UTSW |
5 |
118,899,388 (GRCm39) |
missense |
probably null |
0.99 |
|
R4043:Med13l
|
UTSW |
5 |
118,731,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4593:Med13l
|
UTSW |
5 |
118,880,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Med13l
|
UTSW |
5 |
118,883,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4995:Med13l
|
UTSW |
5 |
118,869,014 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5010:Med13l
|
UTSW |
5 |
118,731,615 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5057:Med13l
|
UTSW |
5 |
118,856,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5369:Med13l
|
UTSW |
5 |
118,862,075 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5446:Med13l
|
UTSW |
5 |
118,880,462 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5564:Med13l
|
UTSW |
5 |
118,880,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Med13l
|
UTSW |
5 |
118,866,730 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5580:Med13l
|
UTSW |
5 |
118,889,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5634:Med13l
|
UTSW |
5 |
118,698,915 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5748:Med13l
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5764:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5765:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6083:Med13l
|
UTSW |
5 |
118,859,551 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6504:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6546:Med13l
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6797:Med13l
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6911:Med13l
|
UTSW |
5 |
118,893,723 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6942:Med13l
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
R7018:Med13l
|
UTSW |
5 |
118,890,051 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7096:Med13l
|
UTSW |
5 |
118,859,991 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7113:Med13l
|
UTSW |
5 |
118,864,330 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7136:Med13l
|
UTSW |
5 |
118,859,587 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7140:Med13l
|
UTSW |
5 |
118,880,037 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7345:Med13l
|
UTSW |
5 |
118,880,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7409:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7410:Med13l
|
UTSW |
5 |
118,698,897 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7432:Med13l
|
UTSW |
5 |
118,890,003 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7486:Med13l
|
UTSW |
5 |
118,866,539 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7509:Med13l
|
UTSW |
5 |
118,886,995 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7722:Med13l
|
UTSW |
5 |
118,885,472 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7802:Med13l
|
UTSW |
5 |
118,866,655 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8081:Med13l
|
UTSW |
5 |
118,866,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8266:Med13l
|
UTSW |
5 |
118,880,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8347:Med13l
|
UTSW |
5 |
118,880,662 (GRCm39) |
missense |
probably benign |
|
|
R8365:Med13l
|
UTSW |
5 |
118,866,709 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8508:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8920:Med13l
|
UTSW |
5 |
118,885,543 (GRCm39) |
nonsense |
probably null |
|
|
R8970:Med13l
|
UTSW |
5 |
118,883,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8994:Med13l
|
UTSW |
5 |
118,866,226 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9045:Med13l
|
UTSW |
5 |
118,880,816 (GRCm39) |
missense |
probably benign |
|
|
R9401:Med13l
|
UTSW |
5 |
118,883,089 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9445:Med13l
|
UTSW |
5 |
118,862,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9446:Med13l
|
UTSW |
5 |
118,876,567 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9714:Med13l
|
UTSW |
5 |
118,866,438 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9777:Med13l
|
UTSW |
5 |
118,887,024 (GRCm39) |
missense |
probably benign |
|
|
R9781:Med13l
|
UTSW |
5 |
118,868,032 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9797:Med13l
|
UTSW |
5 |
118,880,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0065:Med13l
|
UTSW |
5 |
118,867,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Med13l
|
UTSW |
5 |
118,887,706 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGTATTTAAGGTGTCCAGGGG -3'
(R):5'- TTCGATCTGTAGAGCTGCCC -3'
Sequencing Primer
(F):5'- CACTGCTAGGGTCACTAAGATG -3'
(R):5'- GTTCATCTGAGTGATGCC -3'
|
| Posted On |
2020-07-28 |
Incidental Mutation