Incidental Mutation 'R8260:Ccdc88a'
| ID |
640019 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc88a
|
| Ensembl Gene |
ENSMUSG00000032740 |
| Gene Name |
coiled coil domain containing 88A |
| Synonyms |
GIV, Girdin, D130005J21Rik, HkRP1, C330012F17Rik, C130096N06Rik, A430106J12Rik |
| MMRRC Submission |
067685-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8260 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
29323658-29460808 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 29443934 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 1410
(I1410F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000048978
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040182]
[ENSMUST00000140194]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040182
AA Change: I1410F
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000048978
Gene: ENSMUSG00000032740
AA Change: I1410F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HOOK
|
14 |
590 |
8.1e-36 |
PFAM |
|
low complexity region
|
614 |
625 |
N/A |
INTRINSIC |
|
Blast:BRLZ
|
665 |
719 |
6e-22 |
BLAST |
|
low complexity region
|
826 |
839 |
N/A |
INTRINSIC |
|
low complexity region
|
883 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1093 |
1104 |
N/A |
INTRINSIC |
|
coiled coil region
|
1268 |
1385 |
N/A |
INTRINSIC |
|
low complexity region
|
1437 |
1444 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1576 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1609 |
1702 |
2.38e-6 |
PROSPERO |
|
internal_repeat_1
|
1708 |
1808 |
2.38e-6 |
PROSPERO |
|
low complexity region
|
1811 |
1824 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000119173
Gene: ENSMUSG00000032740
AA Change: I390F
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
212 |
N/A |
INTRINSIC |
|
coiled coil region
|
248 |
365 |
N/A |
INTRINSIC |
|
low complexity region
|
418 |
425 |
N/A |
INTRINSIC |
|
low complexity region
|
547 |
557 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140194
AA Change: I110F
PolyPhen 2
Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)
|
| SMART Domains |
Protein: ENSMUSP00000114942
Gene: ENSMUSG00000032740
AA Change: I110F
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
3 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
144 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
304 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal weight loss, reduced angiogenesis, and premature death by P25. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930578I06Rik |
G |
C |
14: 64,223,633 (GRCm39) |
L48V |
probably benign |
Het |
| Acbd3 |
T |
C |
1: 180,566,095 (GRCm39) |
Y263H |
probably damaging |
Het |
| Acot4 |
C |
A |
12: 84,088,809 (GRCm39) |
P219Q |
possibly damaging |
Het |
| Adcy6 |
A |
G |
15: 98,498,919 (GRCm39) |
F294S |
probably damaging |
Het |
| Ahcyl |
T |
C |
16: 45,974,786 (GRCm39) |
E197G |
probably damaging |
Het |
| Aplf |
T |
C |
6: 87,606,987 (GRCm39) |
R476G |
probably benign |
Het |
| Arid1b |
A |
G |
17: 5,382,788 (GRCm39) |
T1292A |
probably benign |
Het |
| Atp2c1 |
T |
A |
9: 105,295,778 (GRCm39) |
I649F |
probably damaging |
Het |
| Bbs10 |
C |
T |
10: 111,136,104 (GRCm39) |
Q406* |
probably null |
Het |
| Bcas3 |
T |
A |
11: 85,400,372 (GRCm39) |
M447K |
possibly damaging |
Het |
| Bmal1 |
A |
T |
7: 112,884,258 (GRCm39) |
I92F |
probably damaging |
Het |
| Cars1 |
T |
C |
7: 143,139,446 (GRCm39) |
D214G |
probably benign |
Het |
| Cd55b |
A |
T |
1: 130,316,415 (GRCm39) |
L378H |
probably damaging |
Het |
| Cdh1 |
G |
A |
8: 107,330,979 (GRCm39) |
E37K |
probably benign |
Het |
| Cep72 |
T |
C |
13: 74,206,465 (GRCm39) |
Y119C |
probably damaging |
Het |
| Ctnnd2 |
A |
G |
15: 30,634,879 (GRCm39) |
T176A |
possibly damaging |
Het |
| D630045J12Rik |
T |
A |
6: 38,119,846 (GRCm39) |
|
probably null |
Het |
| Ddi1 |
A |
T |
9: 6,265,524 (GRCm39) |
C282S |
probably damaging |
Het |
| Ddit4 |
T |
C |
10: 59,787,277 (GRCm39) |
T20A |
probably benign |
Het |
| Dpp10 |
T |
A |
1: 123,614,024 (GRCm39) |
T102S |
probably benign |
Het |
| Ep400 |
T |
A |
5: 110,903,478 (GRCm39) |
K374* |
probably null |
Het |
| Epha3 |
A |
G |
16: 63,403,917 (GRCm39) |
L728P |
probably damaging |
Het |
| Fbxw21 |
C |
A |
9: 108,975,614 (GRCm39) |
|
probably null |
Het |
| Frmpd1 |
A |
G |
4: 45,244,638 (GRCm39) |
E109G |
probably damaging |
Het |
| Ggt1 |
C |
T |
10: 75,417,245 (GRCm39) |
P332L |
probably damaging |
Het |
| Gm4779 |
G |
C |
X: 100,837,390 (GRCm39) |
T171S |
possibly damaging |
Het |
| Gm5431 |
A |
T |
11: 48,785,556 (GRCm39) |
I273K |
probably benign |
Het |
| Gon4l |
A |
G |
3: 88,799,937 (GRCm39) |
N861D |
probably damaging |
Het |
| Grm5 |
T |
C |
7: 87,724,340 (GRCm39) |
|
probably null |
Het |
| Helt |
T |
C |
8: 46,745,745 (GRCm39) |
N84S |
possibly damaging |
Het |
| Hnrnpa0 |
G |
T |
13: 58,275,228 (GRCm39) |
Y300* |
probably null |
Het |
| Ints1 |
T |
C |
5: 139,750,968 (GRCm39) |
T810A |
|
Het |
| Irf2bp1 |
C |
T |
7: 18,740,079 (GRCm39) |
A573V |
possibly damaging |
Het |
| Itgbl1 |
C |
A |
14: 124,065,246 (GRCm39) |
D133E |
probably benign |
Het |
| Kctd15 |
A |
G |
7: 34,344,267 (GRCm39) |
F128S |
possibly damaging |
Het |
| Klra17 |
T |
A |
6: 129,808,421 (GRCm39) |
N271Y |
probably damaging |
Het |
| Kmt2c |
T |
A |
5: 25,610,514 (GRCm39) |
E197D |
possibly damaging |
Het |
| Larp1 |
C |
A |
11: 57,949,515 (GRCm39) |
T1048K |
probably benign |
Het |
| Macf1 |
A |
G |
4: 123,365,863 (GRCm39) |
V2966A |
probably benign |
Het |
| Magi3 |
A |
G |
3: 103,922,625 (GRCm39) |
L1364P |
probably benign |
Het |
| Malrd1 |
T |
C |
2: 15,619,017 (GRCm39) |
S294P |
|
Het |
| Med13l |
C |
T |
5: 118,886,794 (GRCm39) |
T1565I |
possibly damaging |
Het |
| Mov10l1 |
A |
G |
15: 88,896,313 (GRCm39) |
D719G |
probably benign |
Het |
| Mtcl3 |
T |
A |
10: 29,024,270 (GRCm39) |
H395Q |
possibly damaging |
Het |
| Muc4 |
CAC |
CACTAC |
16: 32,575,367 (GRCm39) |
|
probably benign |
Het |
| Myh14 |
T |
C |
7: 44,264,800 (GRCm39) |
E1654G |
probably damaging |
Het |
| Myo1c |
C |
T |
11: 75,546,942 (GRCm39) |
|
probably benign |
Het |
| Myo9a |
A |
G |
9: 59,817,961 (GRCm39) |
T2343A |
probably benign |
Het |
| Or1j12 |
A |
G |
2: 36,342,897 (GRCm39) |
Q100R |
probably damaging |
Het |
| Or2ag18 |
A |
T |
7: 106,405,234 (GRCm39) |
V145E |
possibly damaging |
Het |
| Or2d2b |
A |
T |
7: 106,706,062 (GRCm39) |
M2K |
probably benign |
Het |
| Or4m1 |
T |
C |
14: 50,557,615 (GRCm39) |
K226E |
probably benign |
Het |
| Or52m2 |
T |
A |
7: 102,263,432 (GRCm39) |
I255F |
possibly damaging |
Het |
| Or52n5 |
T |
A |
7: 104,587,879 (GRCm39) |
Y49N |
probably damaging |
Het |
| Or6c2 |
T |
A |
10: 129,362,957 (GRCm39) |
I287N |
possibly damaging |
Het |
| Or8k53 |
T |
A |
2: 86,177,276 (GRCm39) |
Y278F |
possibly damaging |
Het |
| Or9g3 |
A |
T |
2: 85,589,820 (GRCm39) |
L300Q |
probably damaging |
Het |
| Osmr |
A |
T |
15: 6,844,897 (GRCm39) |
D957E |
probably benign |
Het |
| Pappa |
T |
A |
4: 65,234,419 (GRCm39) |
V1408E |
probably damaging |
Het |
| Pcnx3 |
C |
T |
19: 5,715,412 (GRCm39) |
G1946E |
probably damaging |
Het |
| Pdcd6ip |
A |
T |
9: 113,501,865 (GRCm39) |
D464E |
probably benign |
Het |
| Pde1c |
T |
C |
6: 56,114,404 (GRCm39) |
Y503C |
probably benign |
Het |
| Potefam3d |
A |
T |
8: 69,972,400 (GRCm39) |
D116E |
possibly damaging |
Het |
| Prob1 |
T |
A |
18: 35,787,210 (GRCm39) |
E348V |
possibly damaging |
Het |
| Rnls |
A |
G |
19: 33,180,048 (GRCm39) |
L134S |
probably damaging |
Het |
| Scrn3 |
T |
C |
2: 73,166,202 (GRCm39) |
Y412H |
probably damaging |
Het |
| Serpina3g |
T |
C |
12: 104,205,362 (GRCm39) |
S34P |
probably benign |
Het |
| Sertad3 |
G |
A |
7: 27,175,784 (GRCm39) |
A73T |
probably benign |
Het |
| Sez6l |
C |
T |
5: 112,609,122 (GRCm39) |
A576T |
probably benign |
Het |
| Sh3tc2 |
G |
A |
18: 62,146,137 (GRCm39) |
R1172H |
probably damaging |
Het |
| Sirt3 |
A |
G |
7: 140,456,319 (GRCm39) |
V110A |
|
Het |
| Smpd3 |
A |
T |
8: 106,984,047 (GRCm39) |
D557E |
probably benign |
Het |
| Sptssb |
A |
T |
3: 69,728,305 (GRCm39) |
M44K |
probably damaging |
Het |
| Tars2 |
A |
G |
3: 95,662,132 (GRCm39) |
W7R |
probably damaging |
Het |
| Tbc1d9b |
A |
G |
11: 50,055,013 (GRCm39) |
D964G |
probably benign |
Het |
| Tiam2 |
A |
T |
17: 3,568,594 (GRCm39) |
D1580V |
possibly damaging |
Het |
| Tmeff2 |
T |
A |
1: 50,977,478 (GRCm39) |
V130D |
probably damaging |
Het |
| Top2a |
T |
A |
11: 98,891,595 (GRCm39) |
E1176V |
probably null |
Het |
| Trappc9 |
C |
A |
15: 72,813,758 (GRCm39) |
E680* |
probably null |
Het |
| Trip10 |
A |
G |
17: 57,564,314 (GRCm39) |
N355S |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,596,337 (GRCm39) |
E20192G |
probably damaging |
Het |
| Vmn2r96 |
A |
G |
17: 18,804,243 (GRCm39) |
M306V |
probably benign |
Het |
| Wdr90 |
A |
T |
17: 26,064,141 (GRCm39) |
H1860Q |
probably damaging |
Het |
| Wrnip1 |
A |
G |
13: 32,989,339 (GRCm39) |
I276V |
possibly damaging |
Het |
| Zfp608 |
T |
C |
18: 55,030,821 (GRCm39) |
K1040E |
possibly damaging |
Het |
| Zfp808 |
T |
A |
13: 62,320,552 (GRCm39) |
C594S |
probably benign |
Het |
|
| Other mutations in Ccdc88a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00499:Ccdc88a
|
APN |
11 |
29,449,341 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL00577:Ccdc88a
|
APN |
11 |
29,374,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00766:Ccdc88a
|
APN |
11 |
29,451,046 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01384:Ccdc88a
|
APN |
11 |
29,453,915 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01541:Ccdc88a
|
APN |
11 |
29,350,283 (GRCm39) |
missense |
probably benign |
|
|
IGL01647:Ccdc88a
|
APN |
11 |
29,454,321 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02648:Ccdc88a
|
APN |
11 |
29,451,051 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02885:Ccdc88a
|
APN |
11 |
29,398,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03117:Ccdc88a
|
APN |
11 |
29,324,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03196:Ccdc88a
|
APN |
11 |
29,432,340 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
trailor
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Ccdc88a
|
UTSW |
11 |
29,324,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0108:Ccdc88a
|
UTSW |
11 |
29,453,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0326:Ccdc88a
|
UTSW |
11 |
29,411,021 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0565:Ccdc88a
|
UTSW |
11 |
29,411,042 (GRCm39) |
unclassified |
probably benign |
|
|
R0631:Ccdc88a
|
UTSW |
11 |
29,443,752 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Ccdc88a
|
UTSW |
11 |
29,432,749 (GRCm39) |
unclassified |
probably benign |
|
|
R0762:Ccdc88a
|
UTSW |
11 |
29,413,112 (GRCm39) |
unclassified |
probably benign |
|
|
R0838:Ccdc88a
|
UTSW |
11 |
29,350,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0946:Ccdc88a
|
UTSW |
11 |
29,406,509 (GRCm39) |
missense |
probably benign |
|
|
R1192:Ccdc88a
|
UTSW |
11 |
29,454,049 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R1500:Ccdc88a
|
UTSW |
11 |
29,432,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1701:Ccdc88a
|
UTSW |
11 |
29,427,427 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1826:Ccdc88a
|
UTSW |
11 |
29,439,637 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1902:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1903:Ccdc88a
|
UTSW |
11 |
29,411,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2021:Ccdc88a
|
UTSW |
11 |
29,453,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2023:Ccdc88a
|
UTSW |
11 |
29,413,546 (GRCm39) |
nonsense |
probably null |
|
|
R2284:Ccdc88a
|
UTSW |
11 |
29,444,099 (GRCm39) |
splice site |
probably null |
|
|
R3236:Ccdc88a
|
UTSW |
11 |
29,397,995 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R3409:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3410:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3411:Ccdc88a
|
UTSW |
11 |
29,436,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3430:Ccdc88a
|
UTSW |
11 |
29,398,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3620:Ccdc88a
|
UTSW |
11 |
29,380,227 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4204:Ccdc88a
|
UTSW |
11 |
29,413,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4515:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4518:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4519:Ccdc88a
|
UTSW |
11 |
29,432,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4693:Ccdc88a
|
UTSW |
11 |
29,432,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Ccdc88a
|
UTSW |
11 |
29,372,586 (GRCm39) |
missense |
probably benign |
|
|
R4707:Ccdc88a
|
UTSW |
11 |
29,397,956 (GRCm39) |
missense |
probably benign |
|
|
R4732:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4733:Ccdc88a
|
UTSW |
11 |
29,435,906 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4734:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4749:Ccdc88a
|
UTSW |
11 |
29,432,720 (GRCm39) |
missense |
probably benign |
|
|
R4817:Ccdc88a
|
UTSW |
11 |
29,410,907 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4828:Ccdc88a
|
UTSW |
11 |
29,413,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4979:Ccdc88a
|
UTSW |
11 |
29,432,133 (GRCm39) |
nonsense |
probably null |
|
|
R5288:Ccdc88a
|
UTSW |
11 |
29,448,416 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5373:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5374:Ccdc88a
|
UTSW |
11 |
29,413,409 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5401:Ccdc88a
|
UTSW |
11 |
29,413,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5586:Ccdc88a
|
UTSW |
11 |
29,453,484 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6660:Ccdc88a
|
UTSW |
11 |
29,432,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7116:Ccdc88a
|
UTSW |
11 |
29,454,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7353:Ccdc88a
|
UTSW |
11 |
29,413,368 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7538:Ccdc88a
|
UTSW |
11 |
29,413,370 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7663:Ccdc88a
|
UTSW |
11 |
29,448,614 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7769:Ccdc88a
|
UTSW |
11 |
29,432,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7798:Ccdc88a
|
UTSW |
11 |
29,427,348 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7810:Ccdc88a
|
UTSW |
11 |
29,435,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7826:Ccdc88a
|
UTSW |
11 |
29,453,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7956:Ccdc88a
|
UTSW |
11 |
29,413,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8402:Ccdc88a
|
UTSW |
11 |
29,413,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8409:Ccdc88a
|
UTSW |
11 |
29,453,544 (GRCm39) |
missense |
probably benign |
|
|
R8555:Ccdc88a
|
UTSW |
11 |
29,380,169 (GRCm39) |
missense |
probably benign |
|
|
R8676:Ccdc88a
|
UTSW |
11 |
29,410,860 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8846:Ccdc88a
|
UTSW |
11 |
29,414,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8963:Ccdc88a
|
UTSW |
11 |
29,448,416 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8972:Ccdc88a
|
UTSW |
11 |
29,435,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9353:Ccdc88a
|
UTSW |
11 |
29,427,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Ccdc88a
|
UTSW |
11 |
29,453,922 (GRCm39) |
missense |
probably null |
0.55 |
|
R9385:Ccdc88a
|
UTSW |
11 |
29,405,422 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9509:Ccdc88a
|
UTSW |
11 |
29,414,143 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9610:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9611:Ccdc88a
|
UTSW |
11 |
29,427,316 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9664:Ccdc88a
|
UTSW |
11 |
29,405,484 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9720:Ccdc88a
|
UTSW |
11 |
29,413,813 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAGGTAATGGTCATAAAGTCATTGG -3'
(R):5'- CAATAATCTGTTTAGAGCACTCACTG -3'
Sequencing Primer
(F):5'- TAAATGAATTGAGACGACAA -3'
(R):5'- ACTCACTGCTGCTCTTCTTGG -3'
|
| Posted On |
2020-07-28 |
Incidental Mutation