Mutagenetix > Incidental Mutation

Incidental Mutation 'R8307:Abca13'

641144

Institutional Source

Beutler Lab

Gene Symbol

Abca13

Ensembl Gene

ENSMUSG00000004668

Gene Name

ATP-binding cassette, sub-family A (ABC1), member 13

Synonyms

A930002G16Rik

MMRRC Submission

067717-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8307 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

9191942-9684259 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 9277922 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Stop codon at position 655 (L655*)

Ref Sequence

ENSEMBL: ENSMUSP00000040465 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042740]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000042740
AA Change: L655*

SMART Domains

Protein: ENSMUSP00000040465
Gene: ENSMUSG00000004668
AA Change: L655*

Domain	Start	End	E-Value	Type
transmembrane domain	20	42	N/A	INTRINSIC
low complexity region	358	379	N/A	INTRINSIC
low complexity region	441	451	N/A	INTRINSIC
low complexity region	820	831	N/A	INTRINSIC
low complexity region	1382	1393	N/A	INTRINSIC
low complexity region	1721	1737	N/A	INTRINSIC
low complexity region	1859	1872	N/A	INTRINSIC
Pfam:ABC2_membrane_3	3288	3740	4.7e-21	PFAM
low complexity region	3796	3809	N/A	INTRINSIC
AAA	3835	4019	8.08e-12	SMART
transmembrane domain	4206	4228	N/A	INTRINSIC
Pfam:ABC2_membrane_3	4317	4646	1.6e-33	PFAM
AAA	4721	4909	8.86e-9	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (56/56)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]

Allele List at MGI

All alleles(3) : Targeted(3)

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2510039O18Rik	C	A	4: 147,941,380 (GRCm38)	T119K	probably benign	Het
Aifm2	A	G	10: 61,726,392 (GRCm38)	Y69C	probably damaging	Het
Atp2c1	C	T	9: 105,442,831 (GRCm38)	V448I	probably benign	Het
Barx2	A	G	9: 31,859,011 (GRCm38)	S74P	probably damaging	Het
Bod1l	T	C	5: 41,821,155 (GRCm38)	K939E	probably damaging	Het
Cdh12	T	A	15: 21,358,864 (GRCm38)	Y125N	probably damaging	Het
Cdh12	C	A	15: 21,358,863 (GRCm38)	F124L	probably benign	Het
Cdx2	A	G	5: 147,306,667 (GRCm38)	Y106H	possibly damaging	Het
Chmp1a	C	T	8: 123,206,241 (GRCm38)	G158S	probably damaging	Het
Cilp	G	A	9: 65,279,004 (GRCm38)	G794S	probably damaging	Het
Cntnap1	A	T	11: 101,188,876 (GRCm38)	Y1277F	possibly damaging	Het
Csde1	A	G	3: 103,039,073 (GRCm38)		probably benign	Het
Dennd4c	A	C	4: 86,825,872 (GRCm38)	D1317A	probably benign	Het
Dgcr2	C	T	16: 17,858,378 (GRCm38)	G176D	probably benign	Het
Dock2	A	T	11: 34,310,362 (GRCm38)	M993K	possibly damaging	Het
Dpy19l1	G	A	9: 24,503,001 (GRCm38)	P44S	probably benign	Het
Dsg2	C	T	18: 20,575,064 (GRCm38)	P74L	probably benign	Het
Epg5	T	A	18: 78,022,679 (GRCm38)	F2078Y	probably damaging	Het
Fancl	A	G	11: 26,399,642 (GRCm38)		probably benign	Het
Fbn1	C	A	2: 125,505,482 (GRCm38)	R41L	possibly damaging	Het
Gemin5	G	A	11: 58,151,594 (GRCm38)	T467M	probably damaging	Het
Hexb	T	C	13: 97,194,199 (GRCm38)	Q102R	probably benign	Het
Hmcn2	A	G	2: 31,396,115 (GRCm38)	D2093G	probably damaging	Het
Hmmr	G	A	11: 40,721,672 (GRCm38)	S206F	probably damaging	Het
Igkv1-131	A	G	6: 67,766,067 (GRCm38)	Y111H	probably damaging	Het
Il6st	G	T	13: 112,487,747 (GRCm38)	G177V	probably benign	Het
Kank4	G	A	4: 98,778,678 (GRCm38)	Q511*	probably null	Het
Krt90	A	G	15: 101,559,199 (GRCm38)	L248P	probably damaging	Het
Krtap5-2	A	G	7: 142,174,849 (GRCm38)	C187R	unknown	Het
Lonp1	C	A	17: 56,626,573 (GRCm38)	A101S	probably benign	Het
Nckap5l	A	G	15: 99,423,177 (GRCm38)	C1241R	probably damaging	Het
Or1j11	A	G	2: 36,422,321 (GRCm38)	T308A	probably benign	Het
Or4c11c	G	A	2: 88,831,289 (GRCm38)	M57I	possibly damaging	Het
Or6c203	T	C	10: 129,174,232 (GRCm38)	D263G	probably benign	Het
Pcdh15	T	A	10: 74,506,475 (GRCm38)	C1131*	probably null	Het
Pcdhgc3	A	G	18: 37,807,794 (GRCm38)	D416G	probably damaging	Het
Pikfyve	T	C	1: 65,245,735 (GRCm38)	M786T	possibly damaging	Het
Pink1	A	T	4: 138,317,962 (GRCm38)	M297K	probably benign	Het
Pln	T	C	10: 53,343,879 (GRCm38)	Y6H	unknown	Het
Ppp2r2c	A	G	5: 36,947,086 (GRCm38)	D270G	probably damaging	Het
Pramel58	T	G	5: 94,683,557 (GRCm38)	L141R	probably damaging	Het
Prcd	A	T	11: 116,659,373 (GRCm38)	T76S	possibly damaging	Het
Pxylp1	A	G	9: 96,839,084 (GRCm38)		probably null	Het
Rab11fip4	A	T	11: 79,690,774 (GRCm38)	N532Y	possibly damaging	Het
Ralgapa1	C	A	12: 55,741,523 (GRCm38)	V592L	probably damaging	Het
Robo2	T	C	16: 73,956,610 (GRCm38)	D793G	probably damaging	Het
Sec14l1	G	A	11: 117,143,416 (GRCm38)		probably null	Het
Srcap	T	A	7: 127,525,369 (GRCm38)	V237E	probably damaging	Het
Srl	A	G	16: 4,497,145 (GRCm38)	I211T	probably benign	Het
Tasor	G	T	14: 27,471,665 (GRCm38)	A941S	probably damaging	Het
Tet3	A	G	6: 83,379,927 (GRCm38)	V883A	probably damaging	Het
Trim46	A	G	3: 89,243,916 (GRCm38)	Y113H	probably benign	Het
Trim58	G	A	11: 58,647,083 (GRCm38)	A267T	probably benign	Het
Tsks	G	A	7: 44,957,662 (GRCm38)	G140S		Het
Vmn2r110	C	A	17: 20,583,057 (GRCm38)	V419L	probably benign	Het
Vmn2r66	A	G	7: 85,007,062 (GRCm38)	F249L	probably benign	Het
Vps8	A	C	16: 21,495,902 (GRCm38)	D584A	probably benign	Het
Zfp605	T	A	5: 110,128,197 (GRCm38)	C394S	probably damaging	Het
Zscan4e	A	G	7: 11,307,132 (GRCm38)	I271T	probably benign	Het

Other mutations in Abca13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Abca13	APN	11	9,297,443 (GRCm38)	missense	probably benign	0.24
IGL00481:Abca13	APN	11	9,290,969 (GRCm38)	missense	probably damaging	0.99
IGL00707:Abca13	APN	11	9,291,586 (GRCm38)	missense	probably damaging	0.99
IGL00755:Abca13	APN	11	9,542,102 (GRCm38)	missense	possibly damaging	0.87
IGL00771:Abca13	APN	11	9,290,870 (GRCm38)	missense	probably damaging	1.00
IGL00802:Abca13	APN	11	9,297,717 (GRCm38)	missense	probably damaging	0.96
IGL00807:Abca13	APN	11	9,378,285 (GRCm38)	missense	probably benign	0.10
IGL00977:Abca13	APN	11	9,399,284 (GRCm38)	missense	probably damaging	1.00
IGL01064:Abca13	APN	11	9,483,855 (GRCm38)	missense	probably benign	0.01
IGL01100:Abca13	APN	11	9,274,673 (GRCm38)	splice site	probably null
IGL01290:Abca13	APN	11	9,256,232 (GRCm38)	missense	probably damaging	1.00
IGL01299:Abca13	APN	11	9,298,743 (GRCm38)	missense	probably benign	0.22
IGL01302:Abca13	APN	11	9,399,470 (GRCm38)	splice site	probably benign
IGL01307:Abca13	APN	11	9,297,159 (GRCm38)	missense	possibly damaging	0.86
IGL01349:Abca13	APN	11	9,292,076 (GRCm38)	missense	probably benign	0.05
IGL01351:Abca13	APN	11	9,267,565 (GRCm38)	missense	probably benign	0.28
IGL01446:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01453:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01461:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01476:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01506:Abca13	APN	11	9,297,447 (GRCm38)	missense	probably benign	0.36
IGL01527:Abca13	APN	11	9,290,788 (GRCm38)	missense	possibly damaging	0.49
IGL01559:Abca13	APN	11	9,309,020 (GRCm38)	missense	possibly damaging	0.82
IGL01580:Abca13	APN	11	9,293,527 (GRCm38)	missense	probably benign	0.00
IGL01679:Abca13	APN	11	9,298,071 (GRCm38)	missense	probably benign	0.07
IGL01731:Abca13	APN	11	9,249,749 (GRCm38)	splice site	probably benign
IGL01762:Abca13	APN	11	9,315,423 (GRCm38)	missense	probably benign	0.18
IGL01781:Abca13	APN	11	9,399,280 (GRCm38)	missense	probably damaging	1.00
IGL01802:Abca13	APN	11	9,292,438 (GRCm38)	missense	probably benign	0.00
IGL01809:Abca13	APN	11	9,290,339 (GRCm38)	missense	probably damaging	0.96
IGL01906:Abca13	APN	11	9,216,225 (GRCm38)	missense	probably damaging	1.00
IGL01928:Abca13	APN	11	9,683,342 (GRCm38)	missense	probably benign	0.13
IGL01940:Abca13	APN	11	9,567,661 (GRCm38)	splice site	probably benign
IGL01993:Abca13	APN	11	9,258,452 (GRCm38)	unclassified	probably benign
IGL02039:Abca13	APN	11	9,297,193 (GRCm38)	nonsense	probably null
IGL02159:Abca13	APN	11	9,314,545 (GRCm38)	missense	probably benign	0.00
IGL02202:Abca13	APN	11	9,288,529 (GRCm38)	missense	possibly damaging	0.55
IGL02268:Abca13	APN	11	9,290,626 (GRCm38)	missense	probably benign	0.00
IGL02332:Abca13	APN	11	9,291,482 (GRCm38)	missense	probably damaging	0.98
IGL02380:Abca13	APN	11	9,291,599 (GRCm38)	missense	possibly damaging	0.73
IGL02466:Abca13	APN	11	9,297,527 (GRCm38)	missense	probably benign	0.00
IGL02505:Abca13	APN	11	9,581,498 (GRCm38)	missense	probably damaging	1.00
IGL02507:Abca13	APN	11	9,399,388 (GRCm38)	missense	probably damaging	1.00
IGL02558:Abca13	APN	11	9,399,387 (GRCm38)	missense	probably damaging	1.00
IGL02581:Abca13	APN	11	9,399,132 (GRCm38)	splice site	probably benign
IGL02586:Abca13	APN	11	9,293,983 (GRCm38)	missense	possibly damaging	0.56
IGL02598:Abca13	APN	11	9,431,898 (GRCm38)	missense	probably damaging	1.00
IGL02747:Abca13	APN	11	9,373,282 (GRCm38)	nonsense	probably null
IGL02893:Abca13	APN	11	9,290,543 (GRCm38)	missense	probably damaging	0.96
IGL02930:Abca13	APN	11	9,378,226 (GRCm38)	missense	possibly damaging	0.86
IGL02967:Abca13	APN	11	9,378,291 (GRCm38)	missense	probably damaging	0.99
IGL02983:Abca13	APN	11	9,290,663 (GRCm38)	missense	probably benign	0.40
IGL02999:Abca13	APN	11	9,581,757 (GRCm38)	splice site	probably benign
IGL03100:Abca13	APN	11	9,258,527 (GRCm38)	missense	probably benign	0.25
IGL03114:Abca13	APN	11	9,528,999 (GRCm38)	missense	probably benign	0.06
IGL03230:Abca13	APN	11	9,294,313 (GRCm38)	missense	probably benign	0.02
IGL03329:Abca13	APN	11	9,298,047 (GRCm38)	missense	probably benign	0.08
IGL03380:Abca13	APN	11	9,298,574 (GRCm38)	missense	probably benign	0.10
IGL02835:Abca13	UTSW	11	9,451,515 (GRCm38)	missense	probably damaging	1.00
PIT4366001:Abca13	UTSW	11	9,294,962 (GRCm38)	missense	probably benign
PIT4458001:Abca13	UTSW	11	9,298,304 (GRCm38)	missense	probably benign	0.05
R0017:Abca13	UTSW	11	9,292,775 (GRCm38)	missense	probably damaging	0.99
R0079:Abca13	UTSW	11	9,293,493 (GRCm38)	missense	probably benign	0.00
R0089:Abca13	UTSW	11	9,292,886 (GRCm38)	missense	possibly damaging	0.76
R0103:Abca13	UTSW	11	9,273,951 (GRCm38)	missense	probably damaging	1.00
R0103:Abca13	UTSW	11	9,273,951 (GRCm38)	missense	probably damaging	1.00
R0113:Abca13	UTSW	11	9,292,114 (GRCm38)	missense	possibly damaging	0.54
R0119:Abca13	UTSW	11	9,298,076 (GRCm38)	missense	probably benign	0.03
R0152:Abca13	UTSW	11	9,581,724 (GRCm38)	missense	probably damaging	0.98
R0255:Abca13	UTSW	11	9,581,545 (GRCm38)	missense	probably damaging	1.00
R0277:Abca13	UTSW	11	9,294,701 (GRCm38)	missense	probably benign	0.25
R0278:Abca13	UTSW	11	9,378,215 (GRCm38)	missense	probably damaging	1.00
R0294:Abca13	UTSW	11	9,269,122 (GRCm38)	splice site	probably null
R0299:Abca13	UTSW	11	9,298,076 (GRCm38)	missense	probably benign	0.03
R0310:Abca13	UTSW	11	9,293,810 (GRCm38)	missense	probably benign	0.36
R0317:Abca13	UTSW	11	9,293,459 (GRCm38)	missense	probably damaging	1.00
R0323:Abca13	UTSW	11	9,294,701 (GRCm38)	missense	probably benign	0.25
R0324:Abca13	UTSW	11	9,297,669 (GRCm38)	missense	possibly damaging	0.76
R0329:Abca13	UTSW	11	9,399,430 (GRCm38)	missense	probably damaging	0.97
R0336:Abca13	UTSW	11	9,298,481 (GRCm38)	missense	probably benign	0.04
R0346:Abca13	UTSW	11	9,566,278 (GRCm38)	missense	probably damaging	0.99
R0380:Abca13	UTSW	11	9,588,500 (GRCm38)	splice site	probably null
R0382:Abca13	UTSW	11	9,636,650 (GRCm38)	splice site	probably benign
R0482:Abca13	UTSW	11	9,328,207 (GRCm38)	missense	possibly damaging	0.88
R0487:Abca13	UTSW	11	9,331,687 (GRCm38)	missense	probably benign	0.07
R0491:Abca13	UTSW	11	9,298,235 (GRCm38)	missense	probably benign	0.02
R0496:Abca13	UTSW	11	9,291,701 (GRCm38)	missense	probably benign	0.01
R0505:Abca13	UTSW	11	9,291,058 (GRCm38)	missense	probably benign	0.00
R0511:Abca13	UTSW	11	9,294,559 (GRCm38)	missense	probably benign
R0525:Abca13	UTSW	11	9,293,371 (GRCm38)	missense	probably damaging	1.00
R0538:Abca13	UTSW	11	9,267,622 (GRCm38)	critical splice donor site	probably null
R0615:Abca13	UTSW	11	9,256,197 (GRCm38)	missense	probably damaging	0.96
R0634:Abca13	UTSW	11	9,314,491 (GRCm38)	missense	possibly damaging	0.59
R0699:Abca13	UTSW	11	9,588,508 (GRCm38)	splice site	probably benign
R0848:Abca13	UTSW	11	9,682,011 (GRCm38)	nonsense	probably null
R0883:Abca13	UTSW	11	9,291,238 (GRCm38)	nonsense	probably null
R0892:Abca13	UTSW	11	9,298,305 (GRCm38)	missense	probably benign	0.00
R0904:Abca13	UTSW	11	9,298,740 (GRCm38)	missense	probably benign	0.22
R0968:Abca13	UTSW	11	9,298,016 (GRCm38)	missense	probably benign	0.00
R1187:Abca13	UTSW	11	9,528,981 (GRCm38)	missense	probably benign	0.00
R1299:Abca13	UTSW	11	9,294,821 (GRCm38)	missense	possibly damaging	0.94
R1323:Abca13	UTSW	11	9,290,937 (GRCm38)	missense	possibly damaging	0.86
R1323:Abca13	UTSW	11	9,290,937 (GRCm38)	missense	possibly damaging	0.86
R1368:Abca13	UTSW	11	9,291,836 (GRCm38)	missense	probably benign
R1387:Abca13	UTSW	11	9,682,085 (GRCm38)	nonsense	probably null
R1436:Abca13	UTSW	11	9,292,646 (GRCm38)	missense	probably damaging	0.99
R1449:Abca13	UTSW	11	9,298,580 (GRCm38)	missense	probably damaging	1.00
R1450:Abca13	UTSW	11	9,430,531 (GRCm38)	splice site	probably benign
R1462:Abca13	UTSW	11	9,483,924 (GRCm38)	splice site	probably benign
R1465:Abca13	UTSW	11	9,399,303 (GRCm38)	missense	probably damaging	1.00
R1465:Abca13	UTSW	11	9,399,303 (GRCm38)	missense	probably damaging	1.00
R1466:Abca13	UTSW	11	9,570,536 (GRCm38)	splice site	probably benign
R1494:Abca13	UTSW	11	9,466,429 (GRCm38)	nonsense	probably null
R1559:Abca13	UTSW	11	9,399,180 (GRCm38)	missense	probably null	1.00
R1564:Abca13	UTSW	11	9,434,316 (GRCm38)	nonsense	probably null
R1698:Abca13	UTSW	11	9,314,507 (GRCm38)	missense	probably benign	0.13
R1728:Abca13	UTSW	11	9,249,680 (GRCm38)	missense	probably benign	0.02
R1734:Abca13	UTSW	11	9,585,460 (GRCm38)	missense	probably benign	0.03
R1781:Abca13	UTSW	11	9,269,194 (GRCm38)	missense	probably damaging	1.00
R1782:Abca13	UTSW	11	9,297,971 (GRCm38)	missense	probably benign	0.36
R1807:Abca13	UTSW	11	9,291,755 (GRCm38)	missense	probably damaging	0.98
R1830:Abca13	UTSW	11	9,290,350 (GRCm38)	missense	probably benign	0.04
R1869:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1870:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1871:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1903:Abca13	UTSW	11	9,466,411 (GRCm38)	missense	probably benign	0.13
R1916:Abca13	UTSW	11	9,534,456 (GRCm38)	missense	probably damaging	1.00
R1936:Abca13	UTSW	11	9,293,595 (GRCm38)	missense	probably benign	0.13
R1976:Abca13	UTSW	11	9,397,815 (GRCm38)	missense	probably damaging	1.00
R2001:Abca13	UTSW	11	9,273,967 (GRCm38)	missense	probably benign	0.01
R2007:Abca13	UTSW	11	9,191,987 (GRCm38)	missense	probably benign	0.19
R2016:Abca13	UTSW	11	9,290,619 (GRCm38)	missense	probably damaging	1.00
R2017:Abca13	UTSW	11	9,290,619 (GRCm38)	missense	probably damaging	1.00
R2034:Abca13	UTSW	11	9,292,628 (GRCm38)	missense	possibly damaging	0.83
R2051:Abca13	UTSW	11	9,328,098 (GRCm38)	missense	probably benign	0.04
R2075:Abca13	UTSW	11	9,522,382 (GRCm38)	missense	probably damaging	1.00
R2118:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2120:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2124:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2148:Abca13	UTSW	11	9,615,764 (GRCm38)	missense	probably damaging	1.00
R2149:Abca13	UTSW	11	9,267,508 (GRCm38)	missense	possibly damaging	0.68
R2157:Abca13	UTSW	11	9,577,170 (GRCm38)	missense	probably damaging	0.97
R2167:Abca13	UTSW	11	9,288,532 (GRCm38)	missense	probably benign	0.19
R2261:Abca13	UTSW	11	9,292,288 (GRCm38)	missense	probably benign
R2263:Abca13	UTSW	11	9,274,702 (GRCm38)	missense	probably benign	0.04
R2281:Abca13	UTSW	11	9,328,136 (GRCm38)	missense	probably damaging	0.98
R2340:Abca13	UTSW	11	9,399,165 (GRCm38)	missense	probably damaging	0.99
R2357:Abca13	UTSW	11	9,297,336 (GRCm38)	missense	probably damaging	1.00
R2370:Abca13	UTSW	11	9,256,185 (GRCm38)	missense	possibly damaging	0.85
R2384:Abca13	UTSW	11	9,267,450 (GRCm38)	splice site	probably benign
R2393:Abca13	UTSW	11	9,275,057 (GRCm38)	nonsense	probably null
R2432:Abca13	UTSW	11	9,451,333 (GRCm38)	splice site	probably benign
R2446:Abca13	UTSW	11	9,275,101 (GRCm38)	missense	probably benign
R2568:Abca13	UTSW	11	9,333,310 (GRCm38)	missense	probably benign	0.40
R2847:Abca13	UTSW	11	9,294,584 (GRCm38)	missense	possibly damaging	0.59
R2860:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2861:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2862:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2877:Abca13	UTSW	11	9,291,889 (GRCm38)	missense	possibly damaging	0.91
R2878:Abca13	UTSW	11	9,291,889 (GRCm38)	missense	possibly damaging	0.91
R3748:Abca13	UTSW	11	9,316,119 (GRCm38)	splice site	probably benign
R3789:Abca13	UTSW	11	9,510,668 (GRCm38)	missense	probably damaging	0.97
R3933:Abca13	UTSW	11	9,354,856 (GRCm38)	missense	probably damaging	1.00
R3981:Abca13	UTSW	11	9,532,407 (GRCm38)	missense	probably benign
R4002:Abca13	UTSW	11	9,585,415 (GRCm38)	missense	probably benign	0.00
R4010:Abca13	UTSW	11	9,622,013 (GRCm38)	splice site	probably benign
R4011:Abca13	UTSW	11	9,622,013 (GRCm38)	splice site	probably benign
R4127:Abca13	UTSW	11	9,191,973 (GRCm38)	missense	probably benign	0.00
R4214:Abca13	UTSW	11	9,293,877 (GRCm38)	missense	probably damaging	0.96
R4236:Abca13	UTSW	11	9,256,205 (GRCm38)	missense	probably damaging	1.00
R4237:Abca13	UTSW	11	9,434,188 (GRCm38)	missense	probably benign	0.01
R4359:Abca13	UTSW	11	9,297,629 (GRCm38)	missense	probably benign	0.02
R4378:Abca13	UTSW	11	9,293,644 (GRCm38)	missense	probably benign	0.00
R4389:Abca13	UTSW	11	9,297,878 (GRCm38)	missense	probably damaging	0.98
R4392:Abca13	UTSW	11	9,309,034 (GRCm38)	missense	possibly damaging	0.94
R4623:Abca13	UTSW	11	9,309,130 (GRCm38)	missense	probably damaging	1.00
R4684:Abca13	UTSW	11	9,434,193 (GRCm38)	nonsense	probably null
R4691:Abca13	UTSW	11	9,434,195 (GRCm38)	missense	probably damaging	1.00
R4700:Abca13	UTSW	11	9,292,306 (GRCm38)	missense	possibly damaging	0.59
R4701:Abca13	UTSW	11	9,292,306 (GRCm38)	missense	possibly damaging	0.59
R4704:Abca13	UTSW	11	9,276,990 (GRCm38)	missense	possibly damaging	0.94
R4751:Abca13	UTSW	11	9,277,973 (GRCm38)	critical splice donor site	probably null
R4772:Abca13	UTSW	11	9,315,339 (GRCm38)	splice site	probably null
R4782:Abca13	UTSW	11	9,328,096 (GRCm38)	missense	probably damaging	0.96
R4801:Abca13	UTSW	11	9,522,341 (GRCm38)	missense	possibly damaging	0.94
R4802:Abca13	UTSW	11	9,522,341 (GRCm38)	missense	possibly damaging	0.94
R4819:Abca13	UTSW	11	9,290,421 (GRCm38)	missense	possibly damaging	0.88
R4831:Abca13	UTSW	11	9,542,077 (GRCm38)	nonsense	probably null
R4851:Abca13	UTSW	11	9,483,890 (GRCm38)	missense	probably benign	0.02
R4857:Abca13	UTSW	11	9,294,143 (GRCm38)	missense	probably benign	0.22
R4869:Abca13	UTSW	11	9,315,434 (GRCm38)	splice site	probably null
R4982:Abca13	UTSW	11	9,292,348 (GRCm38)	missense	possibly damaging	0.58
R5031:Abca13	UTSW	11	9,297,678 (GRCm38)	missense	probably damaging	0.99
R5044:Abca13	UTSW	11	9,373,323 (GRCm38)	missense	possibly damaging	0.80
R5092:Abca13	UTSW	11	9,258,535 (GRCm38)	missense	probably damaging	1.00
R5155:Abca13	UTSW	11	9,532,447 (GRCm38)	missense	probably damaging	0.98
R5173:Abca13	UTSW	11	9,682,032 (GRCm38)	frame shift	probably null
R5180:Abca13	UTSW	11	9,466,510 (GRCm38)	missense	probably benign	0.01
R5244:Abca13	UTSW	11	9,275,081 (GRCm38)	missense	probably benign	0.28
R5257:Abca13	UTSW	11	9,249,684 (GRCm38)	missense	possibly damaging	0.94
R5258:Abca13	UTSW	11	9,249,684 (GRCm38)	missense	possibly damaging	0.94
R5299:Abca13	UTSW	11	9,431,861 (GRCm38)	missense	probably damaging	1.00
R5363:Abca13	UTSW	11	9,277,035 (GRCm38)	missense	possibly damaging	0.75
R5365:Abca13	UTSW	11	9,628,629 (GRCm38)	missense	probably damaging	1.00
R5419:Abca13	UTSW	11	9,193,533 (GRCm38)	critical splice donor site	probably null
R5426:Abca13	UTSW	11	9,290,722 (GRCm38)	missense	probably damaging	1.00
R5468:Abca13	UTSW	11	9,294,062 (GRCm38)	missense	probably damaging	1.00
R5477:Abca13	UTSW	11	9,301,298 (GRCm38)	missense	possibly damaging	0.49
R5541:Abca13	UTSW	11	9,291,545 (GRCm38)	missense	probably benign	0.00
R5553:Abca13	UTSW	11	9,328,158 (GRCm38)	missense	probably damaging	1.00
R5556:Abca13	UTSW	11	9,258,546 (GRCm38)	missense	possibly damaging	0.91
R5566:Abca13	UTSW	11	9,294,615 (GRCm38)	nonsense	probably null
R5582:Abca13	UTSW	11	9,636,639 (GRCm38)	splice site	probably null
R5604:Abca13	UTSW	11	9,566,279 (GRCm38)	missense	probably damaging	0.97
R5609:Abca13	UTSW	11	9,403,874 (GRCm38)	missense	probably benign	0.01
R5617:Abca13	UTSW	11	9,277,891 (GRCm38)	missense	probably benign	0.00
R5693:Abca13	UTSW	11	9,316,233 (GRCm38)	missense	probably benign	0.29
R5707:Abca13	UTSW	11	9,510,620 (GRCm38)	missense	probably damaging	1.00
R5725:Abca13	UTSW	11	9,577,181 (GRCm38)	missense	probably benign	0.00
R5728:Abca13	UTSW	11	9,570,576 (GRCm38)	missense	probably damaging	1.00
R5738:Abca13	UTSW	11	9,621,917 (GRCm38)	missense	probably damaging	1.00
R5758:Abca13	UTSW	11	9,314,536 (GRCm38)	missense	probably damaging	0.97
R5762:Abca13	UTSW	11	9,581,665 (GRCm38)	missense	probably damaging	1.00
R5771:Abca13	UTSW	11	9,291,411 (GRCm38)	missense	probably damaging	1.00
R5809:Abca13	UTSW	11	9,293,692 (GRCm38)	missense	probably damaging	1.00
R5826:Abca13	UTSW	11	9,682,056 (GRCm38)	missense	probably damaging	0.99
R5831:Abca13	UTSW	11	9,567,777 (GRCm38)	nonsense	probably null
R5834:Abca13	UTSW	11	9,277,974 (GRCm38)	critical splice donor site	probably null
R5902:Abca13	UTSW	11	9,297,177 (GRCm38)	missense	probably damaging	1.00
R5933:Abca13	UTSW	11	9,249,658 (GRCm38)	missense	possibly damaging	0.63
R5945:Abca13	UTSW	11	9,293,398 (GRCm38)	missense	probably benign	0.04
R5969:Abca13	UTSW	11	9,292,214 (GRCm38)	nonsense	probably null
R5985:Abca13	UTSW	11	9,291,628 (GRCm38)	missense	probably benign	0.02
R5998:Abca13	UTSW	11	9,567,708 (GRCm38)	missense	probably damaging	0.97
R6021:Abca13	UTSW	11	9,290,465 (GRCm38)	nonsense	probably null
R6022:Abca13	UTSW	11	9,290,759 (GRCm38)	missense	probably damaging	1.00
R6032:Abca13	UTSW	11	9,297,752 (GRCm38)	missense	possibly damaging	0.52
R6032:Abca13	UTSW	11	9,297,752 (GRCm38)	missense	possibly damaging	0.52
R6105:Abca13	UTSW	11	9,397,812 (GRCm38)	missense	probably damaging	1.00
R6153:Abca13	UTSW	11	9,301,259 (GRCm38)	critical splice acceptor site	probably null
R6162:Abca13	UTSW	11	9,309,047 (GRCm38)	missense	probably damaging	1.00
R6187:Abca13	UTSW	11	9,309,085 (GRCm38)	missense	probably damaging	1.00
R6247:Abca13	UTSW	11	9,403,874 (GRCm38)	missense	probably benign	0.01
R6329:Abca13	UTSW	11	9,277,937 (GRCm38)	missense	probably damaging	1.00
R6352:Abca13	UTSW	11	9,309,139 (GRCm38)	splice site	probably null
R6367:Abca13	UTSW	11	9,216,248 (GRCm38)	missense	possibly damaging	0.85
R6423:Abca13	UTSW	11	9,298,778 (GRCm38)	missense	probably benign	0.01
R6424:Abca13	UTSW	11	9,510,542 (GRCm38)	missense	probably benign
R6456:Abca13	UTSW	11	9,290,474 (GRCm38)	missense	possibly damaging	0.94
R6490:Abca13	UTSW	11	9,298,661 (GRCm38)	missense	probably benign	0.00
R6547:Abca13	UTSW	11	9,274,757 (GRCm38)	missense	probably benign	0.04
R6594:Abca13	UTSW	11	9,294,632 (GRCm38)	missense	possibly damaging	0.52
R6604:Abca13	UTSW	11	9,378,384 (GRCm38)	missense	probably damaging	1.00
R6614:Abca13	UTSW	11	9,294,371 (GRCm38)	missense	probably benign	0.04
R6736:Abca13	UTSW	11	9,465,058 (GRCm38)	missense	probably damaging	1.00
R6742:Abca13	UTSW	11	9,328,168 (GRCm38)	missense	probably damaging	1.00
R6791:Abca13	UTSW	11	9,378,504 (GRCm38)	missense	probably damaging	1.00
R6834:Abca13	UTSW	11	9,275,110 (GRCm38)	missense	possibly damaging	0.48
R6936:Abca13	UTSW	11	9,298,568 (GRCm38)	missense	probably damaging	0.96
R6955:Abca13	UTSW	11	9,294,307 (GRCm38)	missense	probably benign	0.28
R7031:Abca13	UTSW	11	9,621,892 (GRCm38)	missense	probably damaging	1.00
R7065:Abca13	UTSW	11	9,292,595 (GRCm38)	missense	probably benign	0.02
R7067:Abca13	UTSW	11	9,291,845 (GRCm38)	missense	probably benign	0.14
R7070:Abca13	UTSW	11	9,290,701 (GRCm38)	missense	probably benign	0.06
R7094:Abca13	UTSW	11	9,298,610 (GRCm38)	missense	probably damaging	0.96
R7102:Abca13	UTSW	11	9,335,215 (GRCm38)	missense	probably damaging	1.00
R7105:Abca13	UTSW	11	9,397,842 (GRCm38)	missense	probably damaging	1.00
R7131:Abca13	UTSW	11	9,291,893 (GRCm38)	missense	probably benign	0.37
R7155:Abca13	UTSW	11	9,529,010 (GRCm38)	missense	probably benign
R7158:Abca13	UTSW	11	9,273,982 (GRCm38)	missense	probably benign
R7212:Abca13	UTSW	11	9,298,854 (GRCm38)	missense	probably benign	0.04
R7215:Abca13	UTSW	11	9,288,405 (GRCm38)	splice site	probably null
R7228:Abca13	UTSW	11	9,297,653 (GRCm38)	missense	probably benign
R7231:Abca13	UTSW	11	9,294,175 (GRCm38)	missense	probably benign	0.25
R7247:Abca13	UTSW	11	9,290,732 (GRCm38)	missense	probably benign	0.00
R7278:Abca13	UTSW	11	9,291,126 (GRCm38)	missense	possibly damaging	0.56
R7299:Abca13	UTSW	11	9,294,649 (GRCm38)	missense	probably damaging	0.98
R7304:Abca13	UTSW	11	9,297,203 (GRCm38)	missense	probably benign
R7328:Abca13	UTSW	11	9,291,545 (GRCm38)	missense	probably benign	0.14
R7374:Abca13	UTSW	11	9,292,136 (GRCm38)	missense	possibly damaging	0.46
R7376:Abca13	UTSW	11	9,291,118 (GRCm38)	missense	probably benign	0.00
R7384:Abca13	UTSW	11	9,333,257 (GRCm38)	missense	probably damaging	1.00
R7395:Abca13	UTSW	11	9,291,658 (GRCm38)	missense	probably benign	0.01
R7419:Abca13	UTSW	11	9,297,833 (GRCm38)	missense	probably damaging	1.00
R7419:Abca13	UTSW	11	9,276,959 (GRCm38)	missense	probably damaging	1.00
R7421:Abca13	UTSW	11	9,510,463 (GRCm38)	missense	probably benign
R7458:Abca13	UTSW	11	9,290,777 (GRCm38)	missense	possibly damaging	0.94
R7474:Abca13	UTSW	11	9,328,088 (GRCm38)	nonsense	probably null
R7492:Abca13	UTSW	11	9,293,167 (GRCm38)	missense	probably benign	0.08
R7660:Abca13	UTSW	11	9,290,678 (GRCm38)	missense	probably benign	0.00
R7677:Abca13	UTSW	11	9,298,349 (GRCm38)	nonsense	probably null
R7744:Abca13	UTSW	11	9,290,421 (GRCm38)	missense	possibly damaging	0.88
R7790:Abca13	UTSW	11	9,297,915 (GRCm38)	missense	probably damaging	1.00
R7798:Abca13	UTSW	11	9,291,664 (GRCm38)	missense	probably benign	0.04
R7811:Abca13	UTSW	11	9,577,141 (GRCm38)	splice site	probably null
R7831:Abca13	UTSW	11	9,297,404 (GRCm38)	missense	possibly damaging	0.46
R7867:Abca13	UTSW	11	9,262,139 (GRCm38)	critical splice donor site	probably null
R7910:Abca13	UTSW	11	9,581,590 (GRCm38)	missense	probably damaging	1.00
R7964:Abca13	UTSW	11	9,316,146 (GRCm38)	missense	probably benign	0.06
R8037:Abca13	UTSW	11	9,293,904 (GRCm38)	missense	probably damaging	1.00
R8049:Abca13	UTSW	11	9,291,867 (GRCm38)	missense	probably damaging	0.99
R8059:Abca13	UTSW	11	9,373,279 (GRCm38)	missense	probably benign	0.00
R8072:Abca13	UTSW	11	9,294,574 (GRCm38)	missense	probably benign	0.10
R8078:Abca13	UTSW	11	9,301,279 (GRCm38)	missense	probably benign	0.32
R8112:Abca13	UTSW	11	9,314,624 (GRCm38)	missense	probably benign	0.01
R8146:Abca13	UTSW	11	9,397,829 (GRCm38)	missense	probably damaging	1.00
R8164:Abca13	UTSW	11	9,615,799 (GRCm38)	missense	probably damaging	1.00
R8195:Abca13	UTSW	11	9,274,735 (GRCm38)	missense	probably benign	0.00
R8220:Abca13	UTSW	11	9,434,299 (GRCm38)	missense	possibly damaging	0.58
R8235:Abca13	UTSW	11	9,262,077 (GRCm38)	missense	probably damaging	0.99
R8310:Abca13	UTSW	11	9,378,269 (GRCm38)	missense	possibly damaging	0.90
R8315:Abca13	UTSW	11	9,585,502 (GRCm38)	missense	probably benign	0.44
R8315:Abca13	UTSW	11	9,378,460 (GRCm38)	missense	probably null	1.00
R8324:Abca13	UTSW	11	9,290,395 (GRCm38)	missense	probably damaging	1.00
R8375:Abca13	UTSW	11	9,397,841 (GRCm38)	missense	probably damaging	1.00
R8375:Abca13	UTSW	11	9,315,416 (GRCm38)	missense	probably benign	0.00
R8400:Abca13	UTSW	11	9,298,218 (GRCm38)	missense	probably damaging	0.97
R8400:Abca13	UTSW	11	9,293,925 (GRCm38)	missense	probably benign	0.00
R8425:Abca13	UTSW	11	9,314,623 (GRCm38)	missense	possibly damaging	0.92
R8486:Abca13	UTSW	11	9,275,092 (GRCm38)	missense	probably benign	0.00
R8493:Abca13	UTSW	11	9,510,668 (GRCm38)	missense	probably damaging	0.97
R8502:Abca13	UTSW	11	9,269,282 (GRCm38)	missense	probably benign	0.02
R8716:Abca13	UTSW	11	9,293,774 (GRCm38)	missense	probably benign	0.09
R8787:Abca13	UTSW	11	9,275,053 (GRCm38)	missense	possibly damaging	0.92
R8829:Abca13	UTSW	11	9,621,881 (GRCm38)	missense	probably damaging	1.00
R8859:Abca13	UTSW	11	9,378,397 (GRCm38)	missense
R8871:Abca13	UTSW	11	9,298,071 (GRCm38)	missense	probably benign	0.07
R8883:Abca13	UTSW	11	9,333,168 (GRCm38)	missense	probably benign	0.00
R8919:Abca13	UTSW	11	9,291,653 (GRCm38)	missense	possibly damaging	0.84
R8966:Abca13	UTSW	11	9,628,588 (GRCm38)	missense	probably damaging	1.00
R8967:Abca13	UTSW	11	9,292,696 (GRCm38)	missense	probably benign	0.18
R8969:Abca13	UTSW	11	9,277,944 (GRCm38)	missense	probably benign
R8972:Abca13	UTSW	11	9,328,138 (GRCm38)	missense	probably damaging	1.00
R9002:Abca13	UTSW	11	9,291,926 (GRCm38)	missense	possibly damaging	0.94
R9046:Abca13	UTSW	11	9,293,525 (GRCm38)	missense	probably benign	0.04
R9051:Abca13	UTSW	11	9,335,232 (GRCm38)	missense	probably damaging	1.00
R9056:Abca13	UTSW	11	9,464,921 (GRCm38)	missense	probably damaging	1.00
R9061:Abca13	UTSW	11	9,277,847 (GRCm38)	missense	probably benign	0.02
R9072:Abca13	UTSW	11	9,290,834 (GRCm38)	missense	possibly damaging	0.93
R9090:Abca13	UTSW	11	9,291,698 (GRCm38)	missense	probably damaging	0.98
R9127:Abca13	UTSW	11	9,292,080 (GRCm38)	missense	probably benign	0.03
R9164:Abca13	UTSW	11	9,328,157 (GRCm38)	missense	probably damaging	1.00
R9175:Abca13	UTSW	11	9,581,593 (GRCm38)	missense	probably damaging	0.98
R9190:Abca13	UTSW	11	9,291,886 (GRCm38)	missense	probably damaging	0.96
R9244:Abca13	UTSW	11	9,291,577 (GRCm38)	missense	probably benign	0.01
R9255:Abca13	UTSW	11	9,328,213 (GRCm38)	missense	probably damaging	1.00
R9271:Abca13	UTSW	11	9,291,698 (GRCm38)	missense	probably damaging	0.98
R9321:Abca13	UTSW	11	9,510,475 (GRCm38)	missense	probably benign	0.00
R9356:Abca13	UTSW	11	9,256,305 (GRCm38)	missense	probably benign	0.11
R9369:Abca13	UTSW	11	9,378,444 (GRCm38)	missense	probably damaging	1.00
R9423:Abca13	UTSW	11	9,290,395 (GRCm38)	missense	probably damaging	1.00
R9432:Abca13	UTSW	11	9,294,559 (GRCm38)	missense	probably benign	0.00
R9455:Abca13	UTSW	11	9,403,897 (GRCm38)	missense	probably damaging	1.00
R9486:Abca13	UTSW	11	9,290,621 (GRCm38)	missense	possibly damaging	0.88
R9492:Abca13	UTSW	11	9,293,667 (GRCm38)	nonsense	probably null
R9511:Abca13	UTSW	11	9,328,130 (GRCm38)	missense	probably benign	0.16
R9545:Abca13	UTSW	11	9,466,538 (GRCm38)	missense	probably damaging	1.00
R9566:Abca13	UTSW	11	9,464,927 (GRCm38)	missense	probably damaging	1.00
R9609:Abca13	UTSW	11	9,258,549 (GRCm38)	missense	probably damaging	1.00
R9616:Abca13	UTSW	11	9,290,501 (GRCm38)	missense	probably benign	0.00
R9651:Abca13	UTSW	11	9,585,484 (GRCm38)	missense	probably benign
R9651:Abca13	UTSW	11	9,293,741 (GRCm38)	missense	probably benign	0.31
R9653:Abca13	UTSW	11	9,293,741 (GRCm38)	missense	probably benign	0.31
R9657:Abca13	UTSW	11	9,293,379 (GRCm38)	missense	probably benign	0.35
R9684:Abca13	UTSW	11	9,333,307 (GRCm38)	missense	probably damaging	1.00
X0013:Abca13	UTSW	11	9,273,899 (GRCm38)	missense	probably benign	0.02
X0057:Abca13	UTSW	11	9,294,744 (GRCm38)	missense	probably damaging	0.96
X0066:Abca13	UTSW	11	9,267,565 (GRCm38)	missense	probably damaging	0.96
Z1088:Abca13	UTSW	11	9,294,687 (GRCm38)	missense	probably damaging	0.99
Z1176:Abca13	UTSW	11	9,267,461 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,251,376 (GRCm38)	missense	possibly damaging	0.88
Z1176:Abca13	UTSW	11	9,335,182 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,335,181 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,294,342 (GRCm38)	missense	probably benign	0.01
Z1177:Abca13	UTSW	11	9,314,545 (GRCm38)	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- GCTGTCATATGTTTTCATGCATTGC -3'
(R):5'- GCCTAGGCTGACAAAGTAGG -3'

Sequencing Primer
(F):5'- CATATGTTTTCATGCATTGCCTTTGG -3'
(R):5'- CAAATAGCTAGCCTCGTTTGCAGG -3'

Posted On

2020-07-28