Incidental Mutation 'R8324:Mtcl1'
| ID |
644027 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mtcl1
|
| Ensembl Gene |
ENSMUSG00000052105 |
| Gene Name |
microtubule crosslinking factor 1 |
| Synonyms |
1110012J17Rik, Soga2, t8219b25 |
| MMRRC Submission |
067725-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.154)
|
| Stock # |
R8324 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
66643977-66756745 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 66743212 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glycine
at position 426
(R426G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083899
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000086693]
[ENSMUST00000097291]
[ENSMUST00000177034]
|
| AlphaFold |
Q3UHU5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000086693
AA Change: R426G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000083899
Gene: ENSMUSG00000052105
AA Change: R426G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
54 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
120 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
166 |
183 |
N/A |
INTRINSIC |
|
low complexity region
|
240 |
259 |
N/A |
INTRINSIC |
|
low complexity region
|
273 |
290 |
N/A |
INTRINSIC |
|
SCOP:d1fxkc_
|
332 |
466 |
3e-7 |
SMART |
|
Blast:BRLZ
|
339 |
362 |
1e-5 |
BLAST |
|
Pfam:DUF3166
|
493 |
587 |
1.8e-34 |
PFAM |
|
Pfam:DUF3166
|
622 |
714 |
3.8e-39 |
PFAM |
|
low complexity region
|
843 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
910 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
coiled coil region
|
1120 |
1159 |
N/A |
INTRINSIC |
|
Pfam:DUF4482
|
1220 |
1344 |
3e-40 |
PFAM |
|
low complexity region
|
1464 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1672 |
1681 |
N/A |
INTRINSIC |
|
low complexity region
|
1912 |
1924 |
N/A |
INTRINSIC |
|
low complexity region
|
1931 |
1943 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000097291
AA Change: R426G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000094894
Gene: ENSMUSG00000052105
AA Change: R426G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
54 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
120 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
166 |
183 |
N/A |
INTRINSIC |
|
low complexity region
|
240 |
259 |
N/A |
INTRINSIC |
|
low complexity region
|
273 |
290 |
N/A |
INTRINSIC |
|
SCOP:d1fxkc_
|
332 |
466 |
3e-7 |
SMART |
|
Blast:BRLZ
|
339 |
362 |
1e-5 |
BLAST |
|
Pfam:DUF3166
|
492 |
588 |
1.8e-43 |
PFAM |
|
Pfam:DUF3166
|
621 |
716 |
5e-19 |
PFAM |
|
low complexity region
|
843 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
910 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
coiled coil region
|
1120 |
1159 |
N/A |
INTRINSIC |
|
Pfam:DUF4482
|
1220 |
1392 |
3.9e-49 |
PFAM |
|
low complexity region
|
1464 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1672 |
1681 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000177034
AA Change: R74G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000135690
Gene: ENSMUSG00000052105
AA Change: R74G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3166
|
140 |
236 |
1.5e-43 |
PFAM |
|
Pfam:DUF3166
|
269 |
364 |
4e-19 |
PFAM |
|
low complexity region
|
491 |
507 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
621 |
N/A |
INTRINSIC |
|
coiled coil region
|
642 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
751 |
N/A |
INTRINSIC |
|
coiled coil region
|
809 |
848 |
N/A |
INTRINSIC |
|
Pfam:DUF4482
|
909 |
1042 |
4e-49 |
PFAM |
|
low complexity region
|
1161 |
1173 |
N/A |
INTRINSIC |
|
low complexity region
|
1369 |
1378 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Global or Purkinje cell-specific homozygous knockout affects Purkinje cell axon and dendrite morphology, resulting in abnormal motor function. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
C |
11: 9,240,395 (GRCm39) |
S753P |
probably damaging |
Het |
| Acan |
A |
G |
7: 78,740,804 (GRCm39) |
E390G |
probably damaging |
Het |
| Antxr2 |
T |
C |
5: 98,086,368 (GRCm39) |
N413S |
probably damaging |
Het |
| Bace2 |
C |
T |
16: 97,158,108 (GRCm39) |
A36V |
possibly damaging |
Het |
| Caprin1 |
G |
A |
2: 103,613,526 (GRCm39) |
R79* |
probably null |
Het |
| Cdan1 |
A |
G |
2: 120,557,806 (GRCm39) |
V507A |
probably benign |
Het |
| Cdkl3 |
T |
A |
11: 51,913,706 (GRCm39) |
|
probably null |
Het |
| Chst5 |
A |
T |
8: 112,617,140 (GRCm39) |
L160Q |
probably benign |
Het |
| Col11a1 |
C |
G |
3: 113,958,059 (GRCm39) |
P1111R |
probably damaging |
Het |
| Col6a6 |
T |
A |
9: 105,632,853 (GRCm39) |
E1470D |
probably benign |
Het |
| Cpped1 |
T |
A |
16: 11,623,340 (GRCm39) |
T274S |
probably benign |
Het |
| Ctnnbl1 |
G |
A |
2: 157,621,735 (GRCm39) |
E75K |
probably damaging |
Het |
| Cyp4f40 |
T |
C |
17: 32,878,502 (GRCm39) |
S15P |
probably benign |
Het |
| Ddx46 |
T |
C |
13: 55,811,727 (GRCm39) |
S643P |
probably damaging |
Het |
| Defb34 |
A |
G |
8: 19,173,814 (GRCm39) |
Q16R |
probably null |
Het |
| Dhrs2 |
T |
A |
14: 55,476,221 (GRCm39) |
V147E |
probably damaging |
Het |
| Dnah5 |
G |
T |
15: 28,347,011 (GRCm39) |
R2498L |
probably damaging |
Het |
| Dpp10 |
T |
A |
1: 123,781,901 (GRCm39) |
I93F |
probably benign |
Het |
| Eef1e1 |
T |
A |
13: 38,839,045 (GRCm39) |
D104V |
probably damaging |
Het |
| Egfr |
A |
G |
11: 16,808,971 (GRCm39) |
Y55C |
probably damaging |
Het |
| Egfr |
A |
C |
11: 16,858,885 (GRCm39) |
I955L |
probably damaging |
Het |
| Ehbp1l1 |
C |
A |
19: 5,770,026 (GRCm39) |
V426F |
possibly damaging |
Het |
| Elp1 |
C |
T |
4: 56,772,491 (GRCm39) |
E877K |
probably damaging |
Het |
| Fam234a |
C |
T |
17: 26,437,672 (GRCm39) |
V108I |
probably benign |
Het |
| Fzd8 |
T |
A |
18: 9,214,688 (GRCm39) |
M590K |
probably damaging |
Het |
| Gm13287 |
T |
C |
4: 88,721,875 (GRCm39) |
S129P |
probably damaging |
Het |
| Heatr5b |
A |
G |
17: 79,062,793 (GRCm39) |
S1919P |
possibly damaging |
Het |
| Hspg2 |
C |
G |
4: 137,246,290 (GRCm39) |
P1023A |
possibly damaging |
Het |
| Itpr2 |
T |
C |
6: 146,229,896 (GRCm39) |
E1233G |
probably damaging |
Het |
| Kcnmb4 |
A |
G |
10: 116,254,219 (GRCm39) |
L186P |
probably damaging |
Het |
| Krt72 |
T |
A |
15: 101,690,580 (GRCm39) |
Y224F |
probably damaging |
Het |
| Loxhd1 |
T |
C |
18: 77,427,275 (GRCm39) |
|
probably null |
Het |
| Lrguk |
A |
G |
6: 34,079,506 (GRCm39) |
T914A |
probably benign |
Het |
| Lrrtm4 |
A |
G |
6: 79,998,974 (GRCm39) |
T129A |
probably damaging |
Het |
| Mmp13 |
A |
T |
9: 7,276,636 (GRCm39) |
I244F |
possibly damaging |
Het |
| Mob1a |
T |
A |
6: 83,306,956 (GRCm39) |
L41Q |
probably damaging |
Het |
| Mybbp1a |
T |
C |
11: 72,336,114 (GRCm39) |
|
probably null |
Het |
| Myh9 |
A |
G |
15: 77,673,117 (GRCm39) |
|
probably null |
Het |
| Myo1d |
T |
A |
11: 80,448,347 (GRCm39) |
D926V |
probably damaging |
Het |
| Ncapg |
T |
G |
5: 45,853,010 (GRCm39) |
H825Q |
probably damaging |
Het |
| Olfml1 |
T |
C |
7: 107,189,570 (GRCm39) |
S212P |
probably benign |
Het |
| Or52p1 |
G |
A |
7: 104,267,321 (GRCm39) |
R145H |
probably benign |
Het |
| Pak2 |
T |
C |
16: 31,871,029 (GRCm39) |
N51S |
probably benign |
Het |
| Papln |
T |
C |
12: 83,833,393 (GRCm39) |
Y1132H |
probably damaging |
Het |
| Pax3 |
T |
A |
1: 78,170,426 (GRCm39) |
R134S |
probably damaging |
Het |
| Pdzrn4 |
A |
G |
15: 92,668,818 (GRCm39) |
E990G |
probably damaging |
Het |
| Peak1 |
A |
T |
9: 56,114,760 (GRCm39) |
W1394R |
probably damaging |
Het |
| Pkn2 |
T |
C |
3: 142,534,771 (GRCm39) |
N285D |
probably benign |
Het |
| Pramel13 |
A |
C |
4: 144,122,427 (GRCm39) |
L39R |
probably damaging |
Het |
| Prrc2a |
A |
G |
17: 35,375,960 (GRCm39) |
S897P |
possibly damaging |
Het |
| Rad51 |
A |
G |
2: 118,954,312 (GRCm39) |
T131A |
possibly damaging |
Het |
| Rc3h2 |
T |
A |
2: 37,290,738 (GRCm39) |
T255S |
possibly damaging |
Het |
| Repin1 |
G |
T |
6: 48,574,279 (GRCm39) |
E403* |
probably null |
Het |
| Rictor |
T |
A |
15: 6,775,043 (GRCm39) |
V125E |
probably damaging |
Het |
| Rps6ka5 |
C |
T |
12: 100,524,746 (GRCm39) |
D664N |
possibly damaging |
Het |
| Rreb1 |
T |
A |
13: 38,131,597 (GRCm39) |
W1584R |
probably damaging |
Het |
| Rxra |
T |
C |
2: 27,631,195 (GRCm39) |
I142T |
probably damaging |
Het |
| Sall2 |
T |
C |
14: 52,550,343 (GRCm39) |
T951A |
probably benign |
Het |
| Slc15a2 |
T |
G |
16: 36,579,669 (GRCm39) |
N359T |
probably damaging |
Het |
| Slc23a1 |
C |
T |
18: 35,755,588 (GRCm39) |
G436E |
probably damaging |
Het |
| Slc6a13 |
T |
C |
6: 121,314,373 (GRCm39) |
*603Q |
probably null |
Het |
| Sptb |
T |
C |
12: 76,665,936 (GRCm39) |
D894G |
possibly damaging |
Het |
| Srgn |
A |
G |
10: 62,343,444 (GRCm39) |
L17P |
probably damaging |
Het |
| Tmprss9 |
T |
C |
10: 80,733,205 (GRCm39) |
|
probably null |
Het |
| Trav9n-4 |
T |
C |
14: 53,532,403 (GRCm39) |
F86L |
probably benign |
Het |
| Trp63 |
A |
G |
16: 25,695,484 (GRCm39) |
Y482C |
unknown |
Het |
| Ttc9b |
G |
T |
7: 27,353,394 (GRCm39) |
A15S |
probably damaging |
Het |
| Urb1 |
A |
T |
16: 90,588,078 (GRCm39) |
I410N |
probably damaging |
Het |
| Vmn2r82 |
A |
T |
10: 79,214,727 (GRCm39) |
K237* |
probably null |
Het |
| Wwox |
G |
A |
8: 115,215,745 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Mtcl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Mtcl1
|
APN |
17 |
66,651,314 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01774:Mtcl1
|
APN |
17 |
66,692,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01918:Mtcl1
|
APN |
17 |
66,675,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02000:Mtcl1
|
APN |
17 |
66,661,185 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02074:Mtcl1
|
APN |
17 |
66,673,463 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02338:Mtcl1
|
APN |
17 |
66,686,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Mtcl1
|
APN |
17 |
66,645,016 (GRCm39) |
missense |
probably benign |
|
|
IGL03034:Mtcl1
|
APN |
17 |
66,651,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03120:Mtcl1
|
APN |
17 |
66,686,378 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03184:Mtcl1
|
APN |
17 |
66,661,209 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03240:Mtcl1
|
APN |
17 |
66,645,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03294:Mtcl1
|
APN |
17 |
66,645,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03332:Mtcl1
|
APN |
17 |
66,645,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4378001:Mtcl1
|
UTSW |
17 |
66,745,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4520001:Mtcl1
|
UTSW |
17 |
66,692,907 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R0110:Mtcl1
|
UTSW |
17 |
66,665,109 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R0113:Mtcl1
|
UTSW |
17 |
66,661,237 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R0321:Mtcl1
|
UTSW |
17 |
66,686,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0366:Mtcl1
|
UTSW |
17 |
66,645,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Mtcl1
|
UTSW |
17 |
66,645,137 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1466:Mtcl1
|
UTSW |
17 |
66,687,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1466:Mtcl1
|
UTSW |
17 |
66,687,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Mtcl1
|
UTSW |
17 |
66,755,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1467:Mtcl1
|
UTSW |
17 |
66,755,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1471:Mtcl1
|
UTSW |
17 |
66,686,143 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1650:Mtcl1
|
UTSW |
17 |
66,692,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Mtcl1
|
UTSW |
17 |
66,687,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mtcl1
|
UTSW |
17 |
66,686,509 (GRCm39) |
missense |
probably benign |
|
|
R1882:Mtcl1
|
UTSW |
17 |
66,686,315 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1935:Mtcl1
|
UTSW |
17 |
66,686,409 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2063:Mtcl1
|
UTSW |
17 |
66,653,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Mtcl1
|
UTSW |
17 |
66,650,618 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2197:Mtcl1
|
UTSW |
17 |
66,673,427 (GRCm39) |
missense |
probably benign |
|
|
R3196:Mtcl1
|
UTSW |
17 |
66,650,829 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3877:Mtcl1
|
UTSW |
17 |
66,649,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4116:Mtcl1
|
UTSW |
17 |
66,673,476 (GRCm39) |
missense |
probably benign |
|
|
R4204:Mtcl1
|
UTSW |
17 |
66,745,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4373:Mtcl1
|
UTSW |
17 |
66,687,074 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4396:Mtcl1
|
UTSW |
17 |
66,651,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4591:Mtcl1
|
UTSW |
17 |
66,655,506 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4610:Mtcl1
|
UTSW |
17 |
66,684,882 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4681:Mtcl1
|
UTSW |
17 |
66,756,139 (GRCm39) |
missense |
unknown |
|
|
R4922:Mtcl1
|
UTSW |
17 |
66,655,474 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4992:Mtcl1
|
UTSW |
17 |
66,649,834 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5169:Mtcl1
|
UTSW |
17 |
66,650,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5542:Mtcl1
|
UTSW |
17 |
66,691,354 (GRCm39) |
intron |
probably benign |
|
|
R5804:Mtcl1
|
UTSW |
17 |
66,650,132 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5998:Mtcl1
|
UTSW |
17 |
66,675,275 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6163:Mtcl1
|
UTSW |
17 |
66,686,326 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6191:Mtcl1
|
UTSW |
17 |
66,650,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Mtcl1
|
UTSW |
17 |
66,665,129 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6260:Mtcl1
|
UTSW |
17 |
66,650,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6524:Mtcl1
|
UTSW |
17 |
66,655,280 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6884:Mtcl1
|
UTSW |
17 |
66,745,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7199:Mtcl1
|
UTSW |
17 |
66,647,534 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7431:Mtcl1
|
UTSW |
17 |
66,649,901 (GRCm39) |
nonsense |
probably null |
|
|
R7479:Mtcl1
|
UTSW |
17 |
66,686,485 (GRCm39) |
missense |
probably benign |
|
|
R7564:Mtcl1
|
UTSW |
17 |
66,678,322 (GRCm39) |
missense |
probably benign |
|
|
R7608:Mtcl1
|
UTSW |
17 |
66,650,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7691:Mtcl1
|
UTSW |
17 |
66,687,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7847:Mtcl1
|
UTSW |
17 |
66,651,328 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7908:Mtcl1
|
UTSW |
17 |
66,678,325 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8262:Mtcl1
|
UTSW |
17 |
66,650,653 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8477:Mtcl1
|
UTSW |
17 |
66,684,942 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8927:Mtcl1
|
UTSW |
17 |
66,755,628 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8928:Mtcl1
|
UTSW |
17 |
66,755,628 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9016:Mtcl1
|
UTSW |
17 |
66,651,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9048:Mtcl1
|
UTSW |
17 |
66,678,331 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9059:Mtcl1
|
UTSW |
17 |
66,650,606 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9221:Mtcl1
|
UTSW |
17 |
66,650,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9327:Mtcl1
|
UTSW |
17 |
66,645,130 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9398:Mtcl1
|
UTSW |
17 |
66,755,462 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R9762:Mtcl1
|
UTSW |
17 |
66,673,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0065:Mtcl1
|
UTSW |
17 |
66,686,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Mtcl1
|
UTSW |
17 |
66,650,723 (GRCm39) |
missense |
probably benign |
0.20 |
|
Z1176:Mtcl1
|
UTSW |
17 |
66,686,455 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Mtcl1
|
UTSW |
17 |
66,651,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTGAGGTGTCCCTAATTCC -3'
(R):5'- AGCGATGCTCAACATGTCGTAC -3'
Sequencing Primer
(F):5'- GTGAGGTGTCCCTAATTCCTAACAAG -3'
(R):5'- GATGCTCAACATGTCGTACTGTCTTC -3'
|
| Posted On |
2020-09-02 |
Incidental Mutation