Incidental Mutation 'R8338:St18'
| ID |
644704 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St18
|
| Ensembl Gene |
ENSMUSG00000033740 |
| Gene Name |
suppression of tumorigenicity 18 |
| Synonyms |
Nzf3, Myt3 |
| MMRRC Submission |
067730-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8338 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
6557455-6931164 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 6879516 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 405
(E405G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042056
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043578]
[ENSMUST00000131494]
[ENSMUST00000140079]
[ENSMUST00000150761]
[ENSMUST00000151281]
[ENSMUST00000163727]
|
| AlphaFold |
Q80TY4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043578
AA Change: E405G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000042056
Gene: ENSMUSG00000033740
AA Change: E405G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131494
AA Change: E405G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000117789
Gene: ENSMUSG00000033740
AA Change: E405G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132207
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140079
AA Change: E405G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000118322
Gene: ENSMUSG00000033740
AA Change: E405G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000150761
AA Change: E405G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000120298
Gene: ENSMUSG00000033740
AA Change: E405G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000151281
AA Change: E405G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000122055
Gene: ENSMUSG00000033740
AA Change: E405G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000163727
AA Change: E405G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000131417
Gene: ENSMUSG00000033740
AA Change: E405G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ache |
T |
C |
5: 137,290,006 (GRCm39) |
L445P |
probably damaging |
Het |
| Agrn |
G |
A |
4: 156,253,018 (GRCm39) |
T1773I |
probably benign |
Het |
| Arap3 |
A |
G |
18: 38,106,683 (GRCm39) |
S1387P |
probably damaging |
Het |
| Bcl11a |
G |
C |
11: 24,114,578 (GRCm39) |
K640N |
probably damaging |
Het |
| Bicd1 |
G |
A |
6: 149,414,621 (GRCm39) |
V445I |
probably benign |
Het |
| Bltp3a |
A |
G |
17: 28,095,669 (GRCm39) |
N26S |
probably damaging |
Het |
| C2cd6 |
A |
C |
1: 59,099,734 (GRCm39) |
N402K |
probably benign |
Het |
| Celsr3 |
C |
T |
9: 108,704,539 (GRCm39) |
Q341* |
probably null |
Het |
| Cers1 |
A |
G |
8: 70,783,772 (GRCm39) |
E240G |
possibly damaging |
Het |
| Cfap157 |
G |
T |
2: 32,668,018 (GRCm39) |
T441N |
possibly damaging |
Het |
| Cfap44 |
G |
A |
16: 44,239,698 (GRCm39) |
|
probably null |
Het |
| Chd1 |
A |
G |
17: 15,990,242 (GRCm39) |
Y1598C |
probably damaging |
Het |
| Ckap2l |
T |
G |
2: 129,126,939 (GRCm39) |
Q413P |
probably damaging |
Het |
| Cobl |
T |
C |
11: 12,203,696 (GRCm39) |
E1002G |
probably benign |
Het |
| Cryge |
G |
A |
1: 65,087,933 (GRCm39) |
T156M |
unknown |
Het |
| Cubn |
A |
C |
2: 13,435,658 (GRCm39) |
F1099L |
probably benign |
Het |
| Cyp7b1 |
T |
C |
3: 18,151,730 (GRCm39) |
E161G |
probably benign |
Het |
| Dnah10 |
A |
G |
5: 124,909,566 (GRCm39) |
E4452G |
probably damaging |
Het |
| Dnah2 |
C |
T |
11: 69,378,122 (GRCm39) |
R1273Q |
probably damaging |
Het |
| Dnah3 |
T |
C |
7: 119,671,104 (GRCm39) |
E593G |
probably benign |
Het |
| Dnah9 |
C |
A |
11: 65,732,067 (GRCm39) |
|
probably null |
Het |
| Dnajc22 |
C |
A |
15: 98,999,022 (GRCm39) |
P69Q |
probably benign |
Het |
| Fam171a2 |
T |
A |
11: 102,329,172 (GRCm39) |
D529V |
probably benign |
Het |
| Fbxl17 |
T |
C |
17: 63,663,753 (GRCm39) |
I579V |
possibly damaging |
Het |
| Fry |
C |
T |
5: 150,282,516 (GRCm39) |
T347M |
probably damaging |
Het |
| Gm13272 |
A |
C |
4: 88,698,364 (GRCm39) |
D93A |
probably benign |
Het |
| Grm4 |
A |
T |
17: 27,653,977 (GRCm39) |
F658I |
probably damaging |
Het |
| Hmcn1 |
G |
A |
1: 150,614,485 (GRCm39) |
T1307I |
probably benign |
Het |
| Igkv12-98 |
G |
A |
6: 68,548,159 (GRCm39) |
S96N |
probably benign |
Het |
| Il2ra |
A |
T |
2: 11,687,885 (GRCm39) |
T222S |
probably benign |
Het |
| Il5ra |
G |
T |
6: 106,689,350 (GRCm39) |
T414K |
probably benign |
Het |
| Isg15 |
T |
A |
4: 156,284,088 (GRCm39) |
I147F |
probably benign |
Het |
| Kif14 |
C |
A |
1: 136,422,416 (GRCm39) |
A902E |
probably damaging |
Het |
| Lcat |
G |
A |
8: 106,666,719 (GRCm39) |
R268C |
probably damaging |
Het |
| Lipa |
T |
C |
19: 34,471,477 (GRCm39) |
N366S |
probably benign |
Het |
| Lrp4 |
A |
G |
2: 91,322,713 (GRCm39) |
T1101A |
probably benign |
Het |
| Man1a |
T |
A |
10: 53,801,643 (GRCm39) |
|
probably null |
Het |
| Mib1 |
A |
G |
18: 10,726,372 (GRCm39) |
D23G |
probably benign |
Het |
| Morc2b |
A |
T |
17: 33,355,387 (GRCm39) |
M795K |
probably benign |
Het |
| Msantd5f1 |
T |
A |
4: 73,605,435 (GRCm39) |
M282K |
possibly damaging |
Het |
| Mycbp2 |
T |
A |
14: 103,372,701 (GRCm39) |
E4048D |
probably damaging |
Het |
| Myo7b |
A |
G |
18: 32,104,408 (GRCm39) |
S1447P |
probably damaging |
Het |
| Myt1 |
A |
T |
2: 181,443,655 (GRCm39) |
T536S |
possibly damaging |
Het |
| Nod1 |
A |
T |
6: 54,920,956 (GRCm39) |
L454Q |
probably damaging |
Het |
| Nrf1 |
T |
A |
6: 30,140,247 (GRCm39) |
W199R |
|
Het |
| Or10w1 |
T |
A |
19: 13,632,216 (GRCm39) |
M141K |
possibly damaging |
Het |
| Or13a27 |
T |
A |
7: 139,925,306 (GRCm39) |
M199L |
probably benign |
Het |
| Or14c44 |
T |
C |
7: 86,061,702 (GRCm39) |
I44T |
probably benign |
Het |
| Or8k27 |
A |
T |
2: 86,275,729 (GRCm39) |
M199K |
probably benign |
Het |
| Or9a4 |
T |
C |
6: 40,548,910 (GRCm39) |
F197L |
probably benign |
Het |
| Ostn |
G |
T |
16: 27,143,285 (GRCm39) |
A38S |
probably benign |
Het |
| Paxbp1 |
A |
T |
16: 90,833,435 (GRCm39) |
D266E |
probably damaging |
Het |
| Pcdhb14 |
G |
T |
18: 37,582,175 (GRCm39) |
G427V |
probably damaging |
Het |
| Pdzrn3 |
A |
T |
6: 101,127,783 (GRCm39) |
M961K |
probably benign |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Prdx5 |
T |
C |
19: 6,884,632 (GRCm39) |
D148G |
probably damaging |
Het |
| Ptprj |
A |
T |
2: 90,301,481 (GRCm39) |
I217N |
possibly damaging |
Het |
| Rccd1 |
A |
T |
7: 79,970,618 (GRCm39) |
L54Q |
possibly damaging |
Het |
| Rfx6 |
T |
A |
10: 51,594,190 (GRCm39) |
V370E |
probably damaging |
Het |
| Sdr16c6 |
C |
T |
4: 4,076,620 (GRCm39) |
C93Y |
probably damaging |
Het |
| Shroom1 |
A |
G |
11: 53,354,107 (GRCm39) |
D9G |
probably benign |
Het |
| Snrpe |
A |
G |
1: 133,536,681 (GRCm39) |
V33A |
probably benign |
Het |
| Spats2 |
T |
A |
15: 99,076,340 (GRCm39) |
D139E |
probably damaging |
Het |
| Spopfm1 |
A |
G |
3: 94,173,285 (GRCm39) |
I94V |
possibly damaging |
Het |
| Strap |
A |
T |
6: 137,718,976 (GRCm39) |
E176V |
possibly damaging |
Het |
| Stxbp5l |
G |
T |
16: 36,994,718 (GRCm39) |
T729K |
probably damaging |
Het |
| Synj2bp |
G |
A |
12: 81,551,326 (GRCm39) |
Q97* |
probably null |
Het |
| Tbc1d32 |
T |
A |
10: 55,904,173 (GRCm39) |
Q1198L |
possibly damaging |
Het |
| Tmem98 |
T |
C |
11: 80,712,135 (GRCm39) |
S191P |
probably benign |
Het |
| Tnn |
C |
T |
1: 159,946,053 (GRCm39) |
G922R |
probably damaging |
Het |
| Treh |
A |
G |
9: 44,595,808 (GRCm39) |
N366S |
probably benign |
Het |
| Ttn |
T |
G |
2: 76,750,136 (GRCm39) |
S3638R |
probably benign |
Het |
| Uggt1 |
A |
G |
1: 36,266,602 (GRCm39) |
L124P |
probably damaging |
Het |
| V1rd19 |
A |
T |
7: 23,702,674 (GRCm39) |
K47* |
probably null |
Het |
| Wdhd1 |
T |
C |
14: 47,506,120 (GRCm39) |
M265V |
probably benign |
Het |
| Wsb1 |
T |
C |
11: 79,137,103 (GRCm39) |
D168G |
probably damaging |
Het |
|
| Other mutations in St18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:St18
|
APN |
1 |
6,872,796 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00840:St18
|
APN |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01016:St18
|
APN |
1 |
6,914,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01116:St18
|
APN |
1 |
6,872,856 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01719:St18
|
APN |
1 |
6,916,020 (GRCm39) |
splice site |
probably benign |
|
|
IGL01885:St18
|
APN |
1 |
6,914,596 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02486:St18
|
APN |
1 |
6,890,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02611:St18
|
APN |
1 |
6,839,114 (GRCm39) |
splice site |
probably benign |
|
|
IGL02742:St18
|
APN |
1 |
6,872,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02953:St18
|
APN |
1 |
6,914,337 (GRCm39) |
splice site |
probably benign |
|
|
IGL02999:St18
|
APN |
1 |
6,887,829 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03092:St18
|
APN |
1 |
6,839,118 (GRCm39) |
splice site |
probably benign |
|
|
Smallish
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03055:St18
|
UTSW |
1 |
6,872,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0089:St18
|
UTSW |
1 |
6,919,172 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0257:St18
|
UTSW |
1 |
6,890,186 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0383:St18
|
UTSW |
1 |
6,873,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0588:St18
|
UTSW |
1 |
6,887,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0989:St18
|
UTSW |
1 |
6,898,105 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1068:St18
|
UTSW |
1 |
6,865,786 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1311:St18
|
UTSW |
1 |
6,915,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:St18
|
UTSW |
1 |
6,915,793 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1723:St18
|
UTSW |
1 |
6,880,909 (GRCm39) |
splice site |
probably benign |
|
|
R1926:St18
|
UTSW |
1 |
6,872,913 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1927:St18
|
UTSW |
1 |
6,872,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2035:St18
|
UTSW |
1 |
6,872,552 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:St18
|
UTSW |
1 |
6,898,195 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2139:St18
|
UTSW |
1 |
6,880,839 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2261:St18
|
UTSW |
1 |
6,915,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2300:St18
|
UTSW |
1 |
6,925,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2322:St18
|
UTSW |
1 |
6,914,348 (GRCm39) |
nonsense |
probably null |
|
|
R2846:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3738:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3739:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3772:St18
|
UTSW |
1 |
6,914,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3805:St18
|
UTSW |
1 |
6,872,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:St18
|
UTSW |
1 |
6,873,117 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4034:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4036:St18
|
UTSW |
1 |
6,898,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4407:St18
|
UTSW |
1 |
6,898,061 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4527:St18
|
UTSW |
1 |
6,925,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:St18
|
UTSW |
1 |
6,887,828 (GRCm39) |
missense |
probably benign |
|
|
R4838:St18
|
UTSW |
1 |
6,873,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5182:St18
|
UTSW |
1 |
6,887,877 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5186:St18
|
UTSW |
1 |
6,872,541 (GRCm39) |
splice site |
probably null |
|
|
R5354:St18
|
UTSW |
1 |
6,914,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5423:St18
|
UTSW |
1 |
6,872,840 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5724:St18
|
UTSW |
1 |
6,841,174 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6182:St18
|
UTSW |
1 |
6,914,342 (GRCm39) |
splice site |
probably null |
|
|
R6491:St18
|
UTSW |
1 |
6,898,209 (GRCm39) |
nonsense |
probably null |
|
|
R6503:St18
|
UTSW |
1 |
6,865,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7037:St18
|
UTSW |
1 |
6,873,260 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7098:St18
|
UTSW |
1 |
6,898,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:St18
|
UTSW |
1 |
6,929,351 (GRCm39) |
missense |
|
|
|
R7144:St18
|
UTSW |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7150:St18
|
UTSW |
1 |
6,873,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7334:St18
|
UTSW |
1 |
6,872,783 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7502:St18
|
UTSW |
1 |
6,898,194 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7729:St18
|
UTSW |
1 |
6,872,761 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7848:St18
|
UTSW |
1 |
6,927,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8088:St18
|
UTSW |
1 |
6,898,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8299:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8690:St18
|
UTSW |
1 |
6,872,788 (GRCm39) |
missense |
probably benign |
|
|
R8753:St18
|
UTSW |
1 |
6,916,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8808:St18
|
UTSW |
1 |
6,880,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8880:St18
|
UTSW |
1 |
6,865,619 (GRCm39) |
nonsense |
probably null |
|
|
R9055:St18
|
UTSW |
1 |
6,873,206 (GRCm39) |
nonsense |
probably null |
|
|
R9292:St18
|
UTSW |
1 |
6,898,106 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9322:St18
|
UTSW |
1 |
6,865,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9530:St18
|
UTSW |
1 |
6,872,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9603:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9611:St18
|
UTSW |
1 |
6,873,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:St18
|
UTSW |
1 |
6,929,246 (GRCm39) |
missense |
|
|
|
R9644:St18
|
UTSW |
1 |
6,929,276 (GRCm39) |
missense |
|
|
|
R9740:St18
|
UTSW |
1 |
6,873,287 (GRCm39) |
nonsense |
probably null |
|
|
R9750:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCTAGGGTAGACACTGACAGTC -3'
(R):5'- ACAGTTCTCTCAATGGATGGCC -3'
Sequencing Primer
(F):5'- AGACATGAACTAGCTTTCTGGG -3'
(R):5'- TCTCAATGGATGGCCTATTATGTC -3'
|
| Posted On |
2020-09-02 |
Incidental Mutation