Mutagenetix > Incidental Mutation

Incidental Mutation 'R8363:Igfn1'

646033

Institutional Source

Beutler Lab

Gene Symbol

Igfn1

Ensembl Gene

ENSMUSG00000051985

Gene Name

immunoglobulin-like and fibronectin type III domain containing 1

Synonyms

9830123M21Rik

MMRRC Submission

067654-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.076) question?

Stock #

R8363 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

135881316-135934080 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 135891625 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 2297 (S2297T)

Ref Sequence

ENSEMBL: ENSMUSP00000129680 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166193]

AlphaFold

no structure available at present

Predicted Effect

SMART Domains

Protein: ENSMUSP00000119230
Gene: ENSMUSG00000051985
AA Change: S681T

Domain	Start	End	E-Value	Type
IG	73	159	1.29e-6	SMART
IG_like	258	344	5.45e1	SMART
IG	354	435	1.79e0	SMART
IG	445	524	3.54e-4	SMART
IG	538	624	4.86e-2	SMART
FN3	627	711	3.99e-10	SMART
FN3	727	810	9.1e-14	SMART
FN3	828	911	1.5e-14	SMART
IG	938	1021	6.41e-2	SMART
FN3	1024	1106	3.2e-9	SMART
IGc2	1152	1219	4.89e-7	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000140703

Predicted Effect

probably benign
Transcript: ENSMUST00000166193
AA Change: S2297T

PolyPhen 2 Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)

SMART Domains

Protein: ENSMUSP00000129680
Gene: ENSMUSG00000051985
AA Change: S2297T

Domain	Start	End	E-Value	Type
low complexity region	90	101	N/A	INTRINSIC
IG	193	279	1.29e-6	SMART
PDB:2LHU\|A	302	365	8e-7	PDB
IG_like	378	464	5.45e1	SMART
IG	474	555	1.79e0	SMART
low complexity region	724	739	N/A	INTRINSIC
internal_repeat_2	838	1006	9.98e-5	PROSPERO
low complexity region	1067	1084	N/A	INTRINSIC
internal_repeat_2	1812	1967	9.98e-5	PROSPERO
Pfam:I-set	2054	2139	6.2e-8	PFAM
IG	2153	2239	4.86e-2	SMART
FN3	2242	2326	3.99e-10	SMART
FN3	2342	2425	9.1e-14	SMART
FN3	2443	2526	1.5e-14	SMART
IG	2553	2636	6.41e-2	SMART
FN3	2639	2721	3.2e-9	SMART
IGc2	2767	2834	4.89e-7	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.2%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2010315B03Rik	T	A	9: 124,055,800 (GRCm39)	I375L		Het
Adamts18	C	T	8: 114,493,795 (GRCm39)	G448D	probably damaging	Het
Bzw2	A	G	12: 36,180,122 (GRCm39)	V35A	probably benign	Het
C2cd4d	C	T	3: 94,271,157 (GRCm39)	T141M	probably benign	Het
Chchd4	T	A	6: 91,444,737 (GRCm39)	K17*	probably null	Het
Cmas	C	T	6: 142,702,554 (GRCm39)	P19L	probably benign	Het
Colec10	A	G	15: 54,274,238 (GRCm39)	H22R	probably benign	Het
D630045J12Rik	T	C	6: 38,125,376 (GRCm39)	D1546G	probably damaging	Het
Dgki	A	T	6: 36,993,613 (GRCm39)	C583S	probably damaging	Het
Dhrs13	G	T	11: 77,925,343 (GRCm39)	V205L	probably damaging	Het
Eif4a3l1	T	G	6: 136,306,453 (GRCm39)	S305A	probably benign	Het
Eppk1	C	T	15: 75,994,319 (GRCm39)	R854Q	probably benign	Het
Erc1	T	C	6: 119,730,260 (GRCm39)	D612G	probably benign	Het
Fam163b	G	A	2: 27,002,650 (GRCm39)	R116C	probably benign	Het
Gm5160	T	C	18: 14,557,929 (GRCm39)	V2A	possibly damaging	Het
Gm8247	A	T	14: 44,823,919 (GRCm39)	I202F		Het
Gnpat	T	C	8: 125,590,038 (GRCm39)	V21A	probably benign	Het
Igkv13-85	A	G	6: 68,907,269 (GRCm39)	Y111H	probably damaging	Het
Il17rd	A	G	14: 26,813,906 (GRCm39)	N206D	probably damaging	Het
Il1r2	G	A	1: 40,160,095 (GRCm39)	V272M	probably damaging	Het
Ivl	T	A	3: 92,479,525 (GRCm39)	H180L	possibly damaging	Het
Kcnq5	G	A	1: 21,549,648 (GRCm39)	R360C	probably damaging	Het
Kirrel2	A	G	7: 30,152,968 (GRCm39)	V350A	probably damaging	Het
Mcpt4	A	G	14: 56,299,692 (GRCm39)	S14P	probably damaging	Het
Mdm2	A	G	10: 117,526,239 (GRCm39)	V449A	probably damaging	Het
Mga	T	C	2: 119,794,407 (GRCm39)	V2697A	probably benign	Het
Mlxipl	T	C	5: 135,135,930 (GRCm39)	F52L	probably benign	Het
Mtarc2	A	G	1: 184,566,055 (GRCm39)		probably null	Het
Ndst3	T	C	3: 123,350,517 (GRCm39)	S623G	possibly damaging	Het
Oas1a	C	T	5: 121,043,902 (GRCm39)	A77T	probably damaging	Het
Or4d1	A	T	11: 87,805,069 (GRCm39)	I221N	probably damaging	Het
Or9a2	T	C	6: 41,748,684 (GRCm39)	Q183R	probably benign	Het
P3h2	A	G	16: 25,811,468 (GRCm39)	F252L	probably damaging	Het
Psme4	A	G	11: 30,762,139 (GRCm39)	D493G	probably damaging	Het
Rab3ip	A	C	10: 116,754,869 (GRCm39)	I229S	probably damaging	Het
Ralgapb	T	C	2: 158,268,119 (GRCm39)	L74P	probably damaging	Het
Scn1a	G	T	2: 66,152,601 (GRCm39)	N804K	probably damaging	Het
Slc22a6	A	T	19: 8,596,386 (GRCm39)	H124L	probably benign	Het
Slc6a6	A	G	6: 91,727,277 (GRCm39)	I492V	probably benign	Het
Snx2	G	T	18: 53,330,936 (GRCm39)	E134*	probably null	Het
Stt3b	A	G	9: 115,083,988 (GRCm39)	I396T	probably damaging	Het
Tcp11	A	G	17: 28,288,221 (GRCm39)	S415P	possibly damaging	Het
Vmn2r67	A	T	7: 84,804,969 (GRCm39)	S48T	probably benign	Het
Vps16	T	A	2: 130,284,161 (GRCm39)	F665L	probably benign	Het
Wdhd1	A	T	14: 47,513,989 (GRCm39)	D22E	probably damaging	Het
Zng1	A	T	19: 24,920,091 (GRCm39)	H175Q	probably benign	Het

Other mutations in Igfn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00753:Igfn1	APN	1	135,894,464 (GRCm39)	missense	probably damaging	1.00
IGL02299:Igfn1	APN	1	135,881,755 (GRCm39)	utr 3 prime	probably benign
Bounty	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R2276_Igfn1_773	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R4058_Igfn1_315	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R0144:Igfn1	UTSW	1	135,889,751 (GRCm39)	missense	probably damaging	0.99
R0190:Igfn1	UTSW	1	135,889,790 (GRCm39)	missense	probably damaging	1.00
R0350:Igfn1	UTSW	1	135,884,505 (GRCm39)	nonsense	probably null
R0413:Igfn1	UTSW	1	135,895,334 (GRCm39)	missense	probably benign	0.23
R0504:Igfn1	UTSW	1	135,896,267 (GRCm39)	missense	probably benign	0.00
R0606:Igfn1	UTSW	1	135,887,639 (GRCm39)	missense	probably damaging	1.00
R0681:Igfn1	UTSW	1	135,891,591 (GRCm39)	missense	possibly damaging	0.88
R0825:Igfn1	UTSW	1	135,890,864 (GRCm39)	missense	probably damaging	1.00
R0839:Igfn1	UTSW	1	135,882,418 (GRCm39)	missense	probably damaging	1.00
R1066:Igfn1	UTSW	1	135,898,463 (GRCm39)	missense	probably benign
R1078:Igfn1	UTSW	1	135,902,585 (GRCm39)	missense	probably damaging	1.00
R1224:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R1569:Igfn1	UTSW	1	135,896,771 (GRCm39)	missense	probably benign
R1626:Igfn1	UTSW	1	135,896,705 (GRCm39)	missense	probably benign	0.29
R1663:Igfn1	UTSW	1	135,896,046 (GRCm39)	missense	probably benign	0.15
R1677:Igfn1	UTSW	1	135,898,839 (GRCm39)	missense	probably damaging	0.99
R1709:Igfn1	UTSW	1	135,883,311 (GRCm39)	missense	probably benign	0.24
R1728:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1728:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1728:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1729:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1729:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1730:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1730:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1739:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1739:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1739:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1746:Igfn1	UTSW	1	135,897,561 (GRCm39)	missense	possibly damaging	0.88
R1762:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1762:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1762:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1783:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1783:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1784:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1784:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1785:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1785:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1785:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1847:Igfn1	UTSW	1	135,897,126 (GRCm39)	missense	probably benign
R1866:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R1921:Igfn1	UTSW	1	135,893,801 (GRCm39)	critical splice donor site	probably null
R1984:Igfn1	UTSW	1	135,889,782 (GRCm39)	missense	probably benign	0.39
R2049:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2049:Igfn1	UTSW	1	135,898,376 (GRCm39)	missense	probably benign
R2098:Igfn1	UTSW	1	135,906,043 (GRCm39)	missense	probably damaging	1.00
R2130:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2141:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2276:Igfn1	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R2425:Igfn1	UTSW	1	135,890,840 (GRCm39)	missense	probably damaging	1.00
R2483:Igfn1	UTSW	1	135,897,275 (GRCm39)	missense	probably benign
R2504:Igfn1	UTSW	1	135,897,054 (GRCm39)	missense	probably benign	0.07
R3109:Igfn1	UTSW	1	135,925,586 (GRCm39)	missense	probably benign	0.12
R3421:Igfn1	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R3423:Igfn1	UTSW	1	135,926,379 (GRCm39)	missense	probably benign	0.01
R3705:Igfn1	UTSW	1	135,896,147 (GRCm39)	missense	probably benign
R3871:Igfn1	UTSW	1	135,896,574 (GRCm39)	missense	probably benign	0.03
R3875:Igfn1	UTSW	1	135,882,352 (GRCm39)	missense	probably damaging	1.00
R3953:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3955:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3957:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3965:Igfn1	UTSW	1	135,895,557 (GRCm39)	missense	probably benign
R4006:Igfn1	UTSW	1	135,910,100 (GRCm39)	splice site	probably null
R4058:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4059:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4370:Igfn1	UTSW	1	135,895,844 (GRCm39)	missense	probably benign	0.00
R4380:Igfn1	UTSW	1	135,895,509 (GRCm39)	missense	probably benign	0.00
R4495:Igfn1	UTSW	1	135,897,416 (GRCm39)	missense	possibly damaging	0.79
R4628:Igfn1	UTSW	1	135,887,468 (GRCm39)	missense	possibly damaging	0.47
R4672:Igfn1	UTSW	1	135,893,107 (GRCm39)	missense	possibly damaging	0.72
R4682:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R4702:Igfn1	UTSW	1	135,894,947 (GRCm39)	missense	possibly damaging	0.71
R4744:Igfn1	UTSW	1	135,910,196 (GRCm39)	missense	probably benign	0.07
R4777:Igfn1	UTSW	1	135,882,600 (GRCm39)	missense	probably benign
R4806:Igfn1	UTSW	1	135,895,095 (GRCm39)	missense	probably benign	0.01
R4840:Igfn1	UTSW	1	135,895,778 (GRCm39)	missense	probably benign	0.00
R4894:Igfn1	UTSW	1	135,882,520 (GRCm39)	missense	probably damaging	1.00
R4998:Igfn1	UTSW	1	135,882,404 (GRCm39)	missense	probably damaging	1.00
R5092:Igfn1	UTSW	1	135,892,564 (GRCm39)	missense	probably benign
R5108:Igfn1	UTSW	1	135,910,179 (GRCm39)	missense	probably benign
R5120:Igfn1	UTSW	1	135,901,240 (GRCm39)	missense	possibly damaging	0.93
R5127:Igfn1	UTSW	1	135,887,634 (GRCm39)	missense	probably damaging	1.00
R5231:Igfn1	UTSW	1	135,894,474 (GRCm39)	missense	probably benign	0.26
R5286:Igfn1	UTSW	1	135,895,599 (GRCm39)	missense	probably benign	0.10
R5307:Igfn1	UTSW	1	135,892,676 (GRCm39)	missense	probably damaging	1.00
R5380:Igfn1	UTSW	1	135,893,825 (GRCm39)	missense	probably damaging	1.00
R5553:Igfn1	UTSW	1	135,895,622 (GRCm39)	missense	probably damaging	1.00
R5660:Igfn1	UTSW	1	135,898,152 (GRCm39)	missense	probably benign	0.01
R5779:Igfn1	UTSW	1	135,894,578 (GRCm39)	missense	probably benign	0.16
R5818:Igfn1	UTSW	1	135,893,864 (GRCm39)	missense	possibly damaging	0.72
R5832:Igfn1	UTSW	1	135,902,533 (GRCm39)	missense	probably damaging	0.96
R5933:Igfn1	UTSW	1	135,898,341 (GRCm39)	nonsense	probably null
R5966:Igfn1	UTSW	1	135,893,152 (GRCm39)	missense	probably damaging	1.00
R6116:Igfn1	UTSW	1	135,898,205 (GRCm39)	missense	probably benign	0.00
R6297:Igfn1	UTSW	1	135,892,399 (GRCm39)	critical splice donor site	probably null
R6652:Igfn1	UTSW	1	135,891,609 (GRCm39)	missense	probably damaging	1.00
R6737:Igfn1	UTSW	1	135,897,605 (GRCm39)	missense	probably benign
R6816:Igfn1	UTSW	1	135,887,466 (GRCm39)	missense	probably benign	0.02
R6886:Igfn1	UTSW	1	135,901,198 (GRCm39)	missense	probably damaging	1.00
R6888:Igfn1	UTSW	1	135,910,218 (GRCm39)	missense	probably benign	0.33
R6975:Igfn1	UTSW	1	135,896,183 (GRCm39)	missense	probably damaging	0.96
R7105:Igfn1	UTSW	1	135,911,956 (GRCm39)	missense	probably benign	0.11
R7114:Igfn1	UTSW	1	135,894,519 (GRCm39)	missense	probably benign	0.01
R7233:Igfn1	UTSW	1	135,897,873 (GRCm39)	missense	probably benign	0.41
R7276:Igfn1	UTSW	1	135,926,376 (GRCm39)	missense	possibly damaging	0.85
R7354:Igfn1	UTSW	1	135,903,770 (GRCm39)	missense	possibly damaging	0.72
R7358:Igfn1	UTSW	1	135,891,738 (GRCm39)	missense	probably damaging	1.00
R7380:Igfn1	UTSW	1	135,889,746 (GRCm39)	missense	probably damaging	1.00
R7389:Igfn1	UTSW	1	135,894,785 (GRCm39)	missense	probably benign	0.00
R7513:Igfn1	UTSW	1	135,887,705 (GRCm39)	missense	probably damaging	1.00
R7718:Igfn1	UTSW	1	135,896,774 (GRCm39)	missense	probably benign
R7769:Igfn1	UTSW	1	135,910,143 (GRCm39)	missense	possibly damaging	0.85
R7810:Igfn1	UTSW	1	135,902,527 (GRCm39)	missense	probably damaging	0.98
R7917:Igfn1	UTSW	1	135,899,706 (GRCm39)	missense	probably damaging	0.99
R7952:Igfn1	UTSW	1	135,891,693 (GRCm39)	missense	probably damaging	0.99
R8041:Igfn1	UTSW	1	135,895,797 (GRCm39)	nonsense	probably null
R8233:Igfn1	UTSW	1	135,895,782 (GRCm39)	missense	probably benign	0.00
R8354:Igfn1	UTSW	1	135,887,619 (GRCm39)	missense	possibly damaging	0.61
R8428:Igfn1	UTSW	1	135,895,520 (GRCm39)	missense	probably damaging	1.00
R8731:Igfn1	UTSW	1	135,925,574 (GRCm39)	missense	probably benign	0.02
R8756:Igfn1	UTSW	1	135,895,698 (GRCm39)	missense	probably benign	0.10
R8797:Igfn1	UTSW	1	135,902,573 (GRCm39)	missense	possibly damaging	0.93
R8913:Igfn1	UTSW	1	135,891,579 (GRCm39)	missense	possibly damaging	0.90
R8927:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R8928:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R9087:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R9109:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9113:Igfn1	UTSW	1	135,883,328 (GRCm39)	missense	probably damaging	1.00
R9117:Igfn1	UTSW	1	135,902,528 (GRCm39)	missense	probably benign	0.03
R9205:Igfn1	UTSW	1	135,903,695 (GRCm39)	missense	probably damaging	0.96
R9251:Igfn1	UTSW	1	135,894,409 (GRCm39)	splice site	probably benign
R9260:Igfn1	UTSW	1	135,907,694 (GRCm39)	missense	probably benign	0.45
R9275:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9277:Igfn1	UTSW	1	135,887,520 (GRCm39)	missense	probably damaging	0.98
R9278:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9287:Igfn1	UTSW	1	135,925,544 (GRCm39)	missense	probably benign	0.33
R9298:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9356:Igfn1	UTSW	1	135,899,825 (GRCm39)	nonsense	probably null
R9371:Igfn1	UTSW	1	135,906,001 (GRCm39)	missense	probably damaging	1.00
R9532:Igfn1	UTSW	1	135,897,229 (GRCm39)	missense	possibly damaging	0.61
R9653:Igfn1	UTSW	1	135,883,323 (GRCm39)	nonsense	probably null
R9666:Igfn1	UTSW	1	135,897,692 (GRCm39)	missense	possibly damaging	0.65
R9741:Igfn1	UTSW	1	135,895,383 (GRCm39)	missense	probably benign	0.00
R9748:Igfn1	UTSW	1	135,926,336 (GRCm39)	missense	possibly damaging	0.89
R9796:Igfn1	UTSW	1	135,897,611 (GRCm39)	missense	probably benign	0.26
Z1176:Igfn1	UTSW	1	135,899,738 (GRCm39)	missense	probably damaging	0.99
Z1177:Igfn1	UTSW	1	135,897,305 (GRCm39)	missense	probably benign	0.26
Z1177:Igfn1	UTSW	1	135,883,547 (GRCm39)	missense	probably damaging	1.00
Z1177:Igfn1	UTSW	1	135,910,164 (GRCm39)	missense	possibly damaging	0.73

Predicted Primers

PCR Primer
(F):5'- GGCTGTATCCTGGCCATAGTAG -3'
(R):5'- GGGGTTAAGTAACATGCCCC -3'

Sequencing Primer
(F):5'- CTGTATCCTGGCCATAGTAGAGAGAG -3'
(R):5'- TCCACGGGTCCTCAGACAAG -3'

Posted On

2020-09-02