Mutagenetix > Incidental Mutation

Incidental Mutation 'R7915:Prrc2c'

647987

Institutional Source

Beutler Lab

Gene Symbol

Prrc2c

Ensembl Gene

ENSMUSG00000040225

Gene Name

proline-rich coiled-coil 2C

Synonyms

9630039I18Rik, Bat2d, 1810043M20Rik, Bat2l2

MMRRC Submission

045963-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.513) question?

Stock #

R7915 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

162499354-162568125 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 162519977 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Alanine at position 2125 (S2125A)

Ref Sequence

ENSEMBL: ENSMUSP00000138433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000028016] [ENSMUST00000182149] [ENSMUST00000182393] [ENSMUST00000182593] [ENSMUST00000182660] [ENSMUST00000183223]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000028016
AA Change: S2123A

PolyPhen 2 Score 0.177 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000028016
Gene: ENSMUSG00000040225
AA Change: S2123A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	164	7.7e-56	PFAM
internal_repeat_2	167	349	4.39e-5	PROSPERO
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000182149
AA Change: S2125A

PolyPhen 2 Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000138548
Gene: ENSMUSG00000040225
AA Change: S2125A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	5.6e-73	PFAM
internal_repeat_1	336	391	1.49e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
internal_repeat_3	754	925	9.16e-5	PROSPERO
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	1.49e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	3.08e-5	PROSPERO
internal_repeat_3	1983	2153	9.16e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000182393
AA Change: S841A

PolyPhen 2 Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000138451
Gene: ENSMUSG00000040225
AA Change: S841A

Domain	Start	End	E-Value	Type
low complexity region	24	51	N/A	INTRINSIC
low complexity region	104	125	N/A	INTRINSIC
low complexity region	431	462	N/A	INTRINSIC
low complexity region	481	519	N/A	INTRINSIC
low complexity region	531	548	N/A	INTRINSIC
low complexity region	560	625	N/A	INTRINSIC
low complexity region	879	893	N/A	INTRINSIC
low complexity region	946	968	N/A	INTRINSIC
low complexity region	988	1002	N/A	INTRINSIC
low complexity region	1037	1054	N/A	INTRINSIC
low complexity region	1143	1154	N/A	INTRINSIC
low complexity region	1274	1297	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000182593
AA Change: S2123A

PolyPhen 2 Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000138674
Gene: ENSMUSG00000040225
AA Change: S2123A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	165	4.1e-70	PFAM
internal_repeat_1	334	389	9.57e-6	PROSPERO
low complexity region	405	412	N/A	INTRINSIC
SCOP:d1eq1a_	445	589	3e-5	SMART
low complexity region	647	667	N/A	INTRINSIC
low complexity region	731	743	N/A	INTRINSIC
internal_repeat_3	752	923	6.11e-5	PROSPERO
coiled coil region	994	1024	N/A	INTRINSIC
low complexity region	1155	1184	N/A	INTRINSIC
low complexity region	1210	1220	N/A	INTRINSIC
internal_repeat_1	1238	1293	9.57e-6	PROSPERO
low complexity region	1306	1333	N/A	INTRINSIC
low complexity region	1386	1407	N/A	INTRINSIC
low complexity region	1713	1744	N/A	INTRINSIC
low complexity region	1763	1801	N/A	INTRINSIC
low complexity region	1813	1830	N/A	INTRINSIC
low complexity region	1842	1907	N/A	INTRINSIC
internal_repeat_2	1960	2146	2.01e-5	PROSPERO
internal_repeat_3	1981	2151	6.11e-5	PROSPERO
low complexity region	2161	2175	N/A	INTRINSIC
low complexity region	2228	2250	N/A	INTRINSIC
low complexity region	2270	2284	N/A	INTRINSIC
low complexity region	2319	2336	N/A	INTRINSIC
low complexity region	2425	2436	N/A	INTRINSIC
low complexity region	2551	2574	N/A	INTRINSIC
low complexity region	2671	2682	N/A	INTRINSIC
low complexity region	2730	2747	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000182660
AA Change: S2125A

PolyPhen 2 Score 0.388 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000138433
Gene: ENSMUSG00000040225
AA Change: S2125A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	7e-73	PFAM
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000183223
AA Change: S699A

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000138698
Gene: ENSMUSG00000040225
AA Change: S699A

Domain	Start	End	E-Value	Type
low complexity region	289	320	N/A	INTRINSIC
low complexity region	339	377	N/A	INTRINSIC
low complexity region	389	406	N/A	INTRINSIC
low complexity region	418	483	N/A	INTRINSIC
low complexity region	739	761	N/A	INTRINSIC
low complexity region	781	795	N/A	INTRINSIC
low complexity region	830	847	N/A	INTRINSIC
low complexity region	936	947	N/A	INTRINSIC
low complexity region	1062	1085	N/A	INTRINSIC
low complexity region	1182	1193	N/A	INTRINSIC
low complexity region	1241	1258	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

97% (66/68)

Allele List at MGI

Other mutations in this stock

Total: 68 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca17	T	G	17: 24,484,507 (GRCm39)	H1585P	probably damaging	Het
Acaca	A	T	11: 84,167,414 (GRCm39)	T1063S	probably benign	Het
Actc1	T	A	2: 113,880,967 (GRCm39)	K86M	probably damaging	Het
Amz1	A	G	5: 140,727,190 (GRCm39)	N51S	probably benign	Het
Arhgap33	G	A	7: 30,222,648 (GRCm39)	P1095S	probably benign	Het
Bicra	T	C	7: 15,722,447 (GRCm39)	T357A	probably benign	Het
C130032M10Rik	A	G	9: 114,345,123 (GRCm39)	R120G	unknown	Het
Cadps	A	G	14: 12,705,544 (GRCm38)	F284L	possibly damaging	Het
Ccdc83	G	A	7: 89,893,290 (GRCm39)	Q156*	probably null	Het
Cdh20	T	A	1: 104,861,898 (GRCm39)	M26K	probably benign	Het
Cdh23	A	G	10: 60,143,668 (GRCm39)	L2979P	probably damaging	Het
Cdhr17	A	G	5: 17,032,012 (GRCm39)	N556D	probably benign	Het
Crocc2	T	C	1: 93,141,363 (GRCm39)	L1172P	probably damaging	Het
Cyp2d10	C	T	15: 82,288,628 (GRCm39)		probably null	Het
Cyp2j9	T	A	4: 96,479,621 (GRCm39)		probably benign	Het
Dgcr2	A	G	16: 17,677,266 (GRCm39)		probably null	Het
Dio3	A	G	12: 110,246,473 (GRCm39)	M270V		Het
Dll1	C	A	17: 15,588,690 (GRCm39)	D662Y	probably damaging	Het
Drd1	G	T	13: 54,207,834 (GRCm39)	P127T	probably damaging	Het
Evc2	T	C	5: 37,544,206 (GRCm39)	S652P	probably damaging	Het
Fam149a	C	A	8: 45,794,280 (GRCm39)	M708I	probably benign	Het
Fam89a	T	C	8: 125,467,895 (GRCm39)	E139G	probably damaging	Het
Gpr141	T	C	13: 19,936,729 (GRCm39)	I15M	probably benign	Het
Hcn4	G	A	9: 58,731,218 (GRCm39)	E142K	unknown	Het
Hivep3	T	A	4: 119,954,962 (GRCm39)	S1093T	possibly damaging	Het
Inpp5f	C	A	7: 128,269,433 (GRCm39)	T261K	probably benign	Het
Ints3	A	T	3: 90,340,132 (GRCm39)	D42E	probably benign	Het
Krt90	A	T	15: 101,466,838 (GRCm39)		probably null	Het
Kti12	A	C	4: 108,705,443 (GRCm39)	E119A	probably benign	Het
Kti12	G	T	4: 108,705,444 (GRCm39)	E119D	probably benign	Het
Lrig1	C	A	6: 94,607,082 (GRCm39)		probably null	Het
Mapk14	A	G	17: 28,947,928 (GRCm39)	T221A	probably benign	Het
Megf10	A	T	18: 57,373,807 (GRCm39)	T202S	probably benign	Het
Neo1	A	T	9: 58,838,264 (GRCm39)	F507I	probably benign	Het
Or7a35	A	G	10: 78,853,264 (GRCm39)	Y36C	probably damaging	Het
Or8b48	A	T	9: 38,492,969 (GRCm39)	Y132F	probably damaging	Het
Or8k37	T	A	2: 86,469,110 (GRCm39)	*314L	probably null	Het
Peg10	T	TCCA	6: 4,756,451 (GRCm39)		probably benign	Het
Pkd1	T	A	17: 24,811,630 (GRCm39)	Y3724*	probably null	Het
Plxnd1	T	C	6: 115,943,879 (GRCm39)	D1140G	probably benign	Het
Pramel22	T	C	4: 143,382,315 (GRCm39)	K127R	possibly damaging	Het
Prex1	A	G	2: 166,463,112 (GRCm39)	S250P	probably damaging	Het
Prom1	A	T	5: 44,162,277 (GRCm39)	M777K	possibly damaging	Het
Ptpn12	A	G	5: 21,214,449 (GRCm39)	I229T	probably damaging	Het
Ranbp6	A	G	19: 29,790,073 (GRCm39)	V93A	probably benign	Het
Rtn3	A	G	19: 7,434,865 (GRCm39)	C376R	probably benign	Het
Sis	A	C	3: 72,828,471 (GRCm39)	H1201Q	probably damaging	Het
Slc20a1	G	A	2: 129,049,757 (GRCm39)	D340N	probably benign	Het
Slc3a2	G	A	19: 8,685,182 (GRCm39)	R535W	probably damaging	Het
Slc5a2	T	A	7: 127,864,966 (GRCm39)	L33Q	probably damaging	Het
Sltm	G	T	9: 70,494,431 (GRCm39)	R927L	probably damaging	Het
Spaca7b	T	C	8: 11,728,645 (GRCm39)	T9A	possibly damaging	Het
Stat1	A	G	1: 52,190,440 (GRCm39)	D565G	probably benign	Het
Terb1	T	C	8: 105,173,848 (GRCm39)	K745R	possibly damaging	Het
Tescl	T	C	7: 24,033,113 (GRCm39)	I71V	probably damaging	Het
Tgm1	T	C	14: 55,937,883 (GRCm39)	D742G	probably damaging	Het
Tmem128	T	A	5: 38,423,875 (GRCm39)	W30R	probably benign	Het
Tox	T	A	4: 6,822,949 (GRCm39)	M123L	probably benign	Het
Tsnaxip1	A	G	8: 106,569,413 (GRCm39)	S547G	possibly damaging	Het
Ttn	T	A	2: 76,567,539 (GRCm39)	K27785*	probably null	Het
Tut7	T	C	13: 59,932,628 (GRCm39)	I1345V	probably benign	Het
Usp38	A	C	8: 81,727,712 (GRCm39)	S340R	probably damaging	Het
Utrn	A	T	10: 12,340,956 (GRCm39)	H2840Q	probably damaging	Het
Vars2	T	C	17: 35,975,731 (GRCm39)	I229V	probably damaging	Het
Vmn1r16	A	T	6: 57,300,380 (GRCm39)	Y81N	probably damaging	Het
Vmn2r98	A	T	17: 19,287,493 (GRCm39)	D442V	probably benign	Het
Vps13d	T	C	4: 144,813,389 (GRCm39)	I3296V		Het
Wwtr1	A	G	3: 57,483,020 (GRCm39)		probably null	Het

Other mutations in Prrc2c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00425:Prrc2c	APN	1	162,548,182 (GRCm39)	splice site	probably null
IGL00577:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL00580:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL01295:Prrc2c	APN	1	162,510,061 (GRCm39)	missense	probably damaging	1.00
IGL01554:Prrc2c	APN	1	162,538,355 (GRCm39)	missense	probably damaging	0.99
IGL01684:Prrc2c	APN	1	162,534,031 (GRCm39)	unclassified	probably benign
IGL01745:Prrc2c	APN	1	162,552,297 (GRCm39)	missense	probably damaging	1.00
IGL01770:Prrc2c	APN	1	162,532,068 (GRCm39)	missense	probably benign	0.23
IGL01905:Prrc2c	APN	1	162,532,898 (GRCm39)	unclassified	probably benign
IGL02304:Prrc2c	APN	1	162,511,705 (GRCm39)	missense	probably benign	0.05
IGL02389:Prrc2c	APN	1	162,520,439 (GRCm39)	missense	probably damaging	1.00
IGL02540:Prrc2c	APN	1	162,550,706 (GRCm39)	missense	probably damaging	1.00
IGL02681:Prrc2c	APN	1	162,533,181 (GRCm39)	unclassified	probably benign
IGL02686:Prrc2c	APN	1	162,535,516 (GRCm39)	unclassified	probably benign
IGL02795:Prrc2c	APN	1	162,541,868 (GRCm39)	missense	probably benign
IGL02894:Prrc2c	APN	1	162,505,626 (GRCm39)	missense	probably damaging	1.00
IGL02957:Prrc2c	APN	1	162,534,104 (GRCm39)	unclassified	probably benign
IGL02981:Prrc2c	APN	1	162,532,748 (GRCm39)	unclassified	probably benign
IGL03070:Prrc2c	APN	1	162,504,978 (GRCm39)	missense	probably damaging	1.00
IGL03096:Prrc2c	APN	1	162,529,928 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0135:Prrc2c	UTSW	1	162,543,052 (GRCm39)	splice site	probably benign
R0279:Prrc2c	UTSW	1	162,543,033 (GRCm39)	missense	probably damaging	1.00
R0363:Prrc2c	UTSW	1	162,525,380 (GRCm39)	missense	unknown
R0436:Prrc2c	UTSW	1	162,532,883 (GRCm39)	unclassified	probably benign
R0605:Prrc2c	UTSW	1	162,509,995 (GRCm39)	missense	probably damaging	1.00
R0696:Prrc2c	UTSW	1	162,536,421 (GRCm39)	critical splice donor site	probably null
R0981:Prrc2c	UTSW	1	162,533,550 (GRCm39)	unclassified	probably benign
R1693:Prrc2c	UTSW	1	162,546,282 (GRCm39)	missense	probably damaging	0.98
R1714:Prrc2c	UTSW	1	162,504,945 (GRCm39)	missense	probably damaging	1.00
R1791:Prrc2c	UTSW	1	162,532,551 (GRCm39)	unclassified	probably benign
R1794:Prrc2c	UTSW	1	162,533,528 (GRCm39)	unclassified	probably benign
R1998:Prrc2c	UTSW	1	162,532,487 (GRCm39)	unclassified	probably benign
R2040:Prrc2c	UTSW	1	162,525,126 (GRCm39)	missense	probably damaging	1.00
R2168:Prrc2c	UTSW	1	162,537,903 (GRCm39)	unclassified	probably benign
R2246:Prrc2c	UTSW	1	162,535,360 (GRCm39)	unclassified	probably benign
R2830:Prrc2c	UTSW	1	162,536,485 (GRCm39)	unclassified	probably benign
R2926:Prrc2c	UTSW	1	162,533,696 (GRCm39)	unclassified	probably benign
R3703:Prrc2c	UTSW	1	162,538,260 (GRCm39)	missense	probably damaging	1.00
R3745:Prrc2c	UTSW	1	162,525,754 (GRCm39)	missense	unknown
R3760:Prrc2c	UTSW	1	162,520,420 (GRCm39)	missense	probably damaging	1.00
R3784:Prrc2c	UTSW	1	162,537,238 (GRCm39)	unclassified	probably benign
R3959:Prrc2c	UTSW	1	162,536,461 (GRCm39)	unclassified	probably benign
R4255:Prrc2c	UTSW	1	162,533,895 (GRCm39)	unclassified	probably benign
R4276:Prrc2c	UTSW	1	162,501,160 (GRCm39)	missense	probably damaging	1.00
R4421:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R4593:Prrc2c	UTSW	1	162,525,101 (GRCm39)	missense	probably damaging	1.00
R4651:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4652:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4660:Prrc2c	UTSW	1	162,508,464 (GRCm39)	missense	probably damaging	1.00
R4677:Prrc2c	UTSW	1	162,532,748 (GRCm39)	unclassified	probably benign
R4688:Prrc2c	UTSW	1	162,525,256 (GRCm39)	missense	unknown
R4753:Prrc2c	UTSW	1	162,518,799 (GRCm39)	missense	probably damaging	1.00
R4790:Prrc2c	UTSW	1	162,538,050 (GRCm39)	missense	unknown
R4981:Prrc2c	UTSW	1	162,520,116 (GRCm39)	missense	probably damaging	1.00
R4995:Prrc2c	UTSW	1	162,532,879 (GRCm39)	unclassified	probably benign
R5119:Prrc2c	UTSW	1	162,533,009 (GRCm39)	unclassified	probably benign
R5127:Prrc2c	UTSW	1	162,525,415 (GRCm39)	missense	unknown
R5291:Prrc2c	UTSW	1	162,533,151 (GRCm39)	unclassified	probably benign
R5474:Prrc2c	UTSW	1	162,537,213 (GRCm39)	unclassified	probably benign
R5543:Prrc2c	UTSW	1	162,501,080 (GRCm39)	missense	probably damaging	0.99
R5579:Prrc2c	UTSW	1	162,508,327 (GRCm39)	critical splice donor site	probably null
R5594:Prrc2c	UTSW	1	162,526,600 (GRCm39)	missense	unknown
R5620:Prrc2c	UTSW	1	162,501,098 (GRCm39)	missense	probably damaging	1.00
R5994:Prrc2c	UTSW	1	162,501,725 (GRCm39)	splice site	probably null
R6142:Prrc2c	UTSW	1	162,537,956 (GRCm39)	missense	unknown
R6199:Prrc2c	UTSW	1	162,510,085 (GRCm39)	missense	probably damaging	1.00
R6277:Prrc2c	UTSW	1	162,541,883 (GRCm39)	missense	probably benign
R6504:Prrc2c	UTSW	1	162,525,364 (GRCm39)	missense	unknown
R6671:Prrc2c	UTSW	1	162,525,154 (GRCm39)	missense	probably damaging	1.00
R6785:Prrc2c	UTSW	1	162,536,670 (GRCm39)	unclassified	probably benign
R6799:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6801:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6850:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6851:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6856:Prrc2c	UTSW	1	162,509,940 (GRCm39)	missense	probably damaging	1.00
R6869:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6882:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6884:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6897:Prrc2c	UTSW	1	162,533,075 (GRCm39)	unclassified	probably benign
R6934:Prrc2c	UTSW	1	162,548,074 (GRCm39)	missense	probably benign	0.10
R6976:Prrc2c	UTSW	1	162,520,413 (GRCm39)	missense	probably damaging	1.00
R7132:Prrc2c	UTSW	1	162,508,850 (GRCm39)	missense	possibly damaging	0.77
R7165:Prrc2c	UTSW	1	162,501,086 (GRCm39)	missense	possibly damaging	0.94
R7282:Prrc2c	UTSW	1	162,507,543 (GRCm39)	missense	possibly damaging	0.59
R7467:Prrc2c	UTSW	1	162,504,932 (GRCm39)	missense	possibly damaging	0.84
R8068:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R8529:Prrc2c	UTSW	1	162,536,663 (GRCm39)	unclassified	probably benign
R8734:Prrc2c	UTSW	1	162,507,081 (GRCm39)	missense	possibly damaging	0.92
R8735:Prrc2c	UTSW	1	162,537,127 (GRCm39)	missense	unknown
R8813:Prrc2c	UTSW	1	162,532,812 (GRCm39)	missense	unknown
R8946:Prrc2c	UTSW	1	162,536,478 (GRCm39)	unclassified	probably benign
R8975:Prrc2c	UTSW	1	162,533,630 (GRCm39)	missense	unknown
R9035:Prrc2c	UTSW	1	162,503,295 (GRCm39)	missense	possibly damaging	0.96
R9185:Prrc2c	UTSW	1	162,532,212 (GRCm39)	missense	unknown
R9261:Prrc2c	UTSW	1	162,505,622 (GRCm39)	missense	possibly damaging	0.48
R9287:Prrc2c	UTSW	1	162,541,843 (GRCm39)	missense	probably benign	0.34
R9289:Prrc2c	UTSW	1	162,507,130 (GRCm39)	missense	probably benign	0.33
R9466:Prrc2c	UTSW	1	162,503,258 (GRCm39)	missense	possibly damaging	0.53
R9523:Prrc2c	UTSW	1	162,525,298 (GRCm39)	missense	unknown
R9542:Prrc2c	UTSW	1	162,508,359 (GRCm39)	missense	possibly damaging	0.88
R9629:Prrc2c	UTSW	1	162,519,959 (GRCm39)	missense	possibly damaging	0.95
R9744:Prrc2c	UTSW	1	162,505,733 (GRCm39)	missense	possibly damaging	0.96
R9748:Prrc2c	UTSW	1	162,535,435 (GRCm39)	missense	unknown
X0020:Prrc2c	UTSW	1	162,535,416 (GRCm39)	unclassified	probably benign
X0039:Prrc2c	UTSW	1	162,532,362 (GRCm39)	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- AGTAAGTTTGCTGTATGCCAGG -3'
(R):5'- GGTCCCATTGGAAAGGAACG -3'

Sequencing Primer
(F):5'- TCTGAGTTAGAGACCAGCCTG -3'
(R):5'- GTCAGAAGCACTGATCCT -3'

Posted On

2020-09-15