Incidental Mutation 'R7935:Pcdhga7'
| ID |
648710 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdhga7
|
| Ensembl Gene |
ENSMUSG00000103472 |
| Gene Name |
protocadherin gamma subfamily A, 7 |
| Synonyms |
|
| MMRRC Submission |
045981-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.262)
|
| Stock # |
R7935 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
37847887-37974926 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 37849562 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 523
(D523G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141704
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000073447]
[ENSMUST00000115661]
[ENSMUST00000192511]
[ENSMUST00000192931]
[ENSMUST00000193414]
[ENSMUST00000193476]
[ENSMUST00000193869]
[ENSMUST00000194190]
[ENSMUST00000194418]
[ENSMUST00000194544]
[ENSMUST00000195112]
[ENSMUST00000195363]
[ENSMUST00000195823]
|
| AlphaFold |
Q6DD96 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000073447
|
| SMART Domains |
Protein: ENSMUSP00000073150
Gene: ENSMUSG00000104346
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CA
|
42 |
128 |
2.15e-2 |
SMART |
|
CA
|
152 |
237 |
4.8e-13 |
SMART |
|
CA
|
261 |
342 |
9.36e-25 |
SMART |
|
CA
|
366 |
447 |
6.62e-25 |
SMART |
|
CA
|
471 |
557 |
6.72e-26 |
SMART |
|
CA
|
588 |
666 |
2.15e-15 |
SMART |
|
Pfam:Cadherin_C_2
|
685 |
768 |
4.8e-24 |
PFAM |
|
Pfam:Cadherin_tail
|
805 |
928 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115661
|
| SMART Domains |
Protein: ENSMUSP00000111325
Gene: ENSMUSG00000103458
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
20 |
131 |
5.3e-2 |
SMART |
|
CA
|
155 |
240 |
1.51e-19 |
SMART |
|
CA
|
264 |
348 |
7.6e-25 |
SMART |
|
CA
|
372 |
453 |
1.42e-24 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
674 |
4.12e-12 |
SMART |
|
low complexity region
|
706 |
721 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_tail
|
796 |
930 |
3.9e-58 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000192511
AA Change: D523G
PolyPhen 2
Score 0.910 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000141704
Gene: ENSMUSG00000103472
AA Change: D523G
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
47 |
133 |
1.57e-2 |
SMART |
|
CA
|
157 |
242 |
3.24e-19 |
SMART |
|
CA
|
266 |
347 |
3.21e-23 |
SMART |
|
CA
|
371 |
452 |
9.08e-23 |
SMART |
|
CA
|
476 |
562 |
1.32e-24 |
SMART |
|
CA
|
593 |
671 |
3.5e-15 |
SMART |
|
transmembrane domain
|
694 |
716 |
N/A |
INTRINSIC |
|
low complexity region
|
916 |
935 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192931
|
| SMART Domains |
Protein: ENSMUSP00000141348
Gene: ENSMUSG00000103037
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
36 |
119 |
8e-3 |
SMART |
|
CA
|
143 |
228 |
1.34e-20 |
SMART |
|
CA
|
252 |
333 |
1.52e-24 |
SMART |
|
CA
|
357 |
438 |
9.22e-24 |
SMART |
|
CA
|
462 |
548 |
1.24e-24 |
SMART |
|
CA
|
579 |
660 |
1.3e-9 |
SMART |
|
transmembrane domain
|
679 |
701 |
N/A |
INTRINSIC |
|
low complexity region
|
899 |
918 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193414
|
| SMART Domains |
Protein: ENSMUSP00000141893
Gene: ENSMUSG00000103567
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
45 |
131 |
2.45e-1 |
SMART |
|
CA
|
155 |
240 |
1.05e-18 |
SMART |
|
CA
|
264 |
345 |
6.52e-24 |
SMART |
|
CA
|
369 |
450 |
5.99e-23 |
SMART |
|
CA
|
474 |
560 |
6.99e-24 |
SMART |
|
CA
|
591 |
669 |
5.31e-15 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000193476
AA Change: D523G
PolyPhen 2
Score 0.980 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000142126
Gene: ENSMUSG00000103472
AA Change: D523G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
47 |
133 |
7.6e-5 |
SMART |
|
CA
|
157 |
242 |
1.6e-21 |
SMART |
|
CA
|
266 |
347 |
1.6e-25 |
SMART |
|
CA
|
371 |
452 |
4.5e-25 |
SMART |
|
CA
|
476 |
562 |
6.6e-27 |
SMART |
|
CA
|
593 |
671 |
1.7e-17 |
SMART |
|
transmembrane domain
|
694 |
716 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193869
|
| SMART Domains |
Protein: ENSMUSP00000141482
Gene: ENSMUSG00000103332
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
CA
|
45 |
131 |
1.64e-2 |
SMART |
|
CA
|
155 |
240 |
6.42e-23 |
SMART |
|
CA
|
264 |
345 |
1.76e-20 |
SMART |
|
CA
|
369 |
450 |
2.27e-23 |
SMART |
|
CA
|
474 |
560 |
1.5e-23 |
SMART |
|
CA
|
591 |
669 |
1.17e-16 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
931 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193984
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194190
|
| SMART Domains |
Protein: ENSMUSP00000142062
Gene: ENSMUSG00000103144
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
CA
|
31 |
131 |
3.16e-2 |
SMART |
|
CA
|
155 |
240 |
5.39e-16 |
SMART |
|
CA
|
264 |
345 |
6.72e-26 |
SMART |
|
CA
|
369 |
450 |
1.32e-24 |
SMART |
|
CA
|
474 |
560 |
4.17e-22 |
SMART |
|
CA
|
591 |
669 |
4.48e-13 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
931 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194418
|
| SMART Domains |
Protein: ENSMUSP00000142140
Gene: ENSMUSG00000103677
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
44 |
130 |
1.64e-2 |
SMART |
|
CA
|
154 |
239 |
3.93e-18 |
SMART |
|
CA
|
263 |
344 |
5.22e-23 |
SMART |
|
CA
|
368 |
449 |
5.02e-25 |
SMART |
|
CA
|
473 |
559 |
2.07e-26 |
SMART |
|
CA
|
590 |
668 |
6.84e-18 |
SMART |
|
transmembrane domain
|
690 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
911 |
930 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194544
|
| SMART Domains |
Protein: ENSMUSP00000141847
Gene: ENSMUSG00000102836
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:CA
|
18 |
66 |
5e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195112
|
| SMART Domains |
Protein: ENSMUSP00000141449
Gene: ENSMUSG00000102748
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
24 |
130 |
8.18e-3 |
SMART |
|
CA
|
154 |
239 |
1.39e-18 |
SMART |
|
CA
|
263 |
344 |
7.91e-23 |
SMART |
|
CA
|
368 |
449 |
2.27e-23 |
SMART |
|
CA
|
473 |
559 |
1.24e-24 |
SMART |
|
CA
|
590 |
671 |
1.3e-9 |
SMART |
|
transmembrane domain
|
690 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
928 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195363
|
| SMART Domains |
Protein: ENSMUSP00000142227
Gene: ENSMUSG00000103585
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
25 |
N/A |
INTRINSIC |
|
CA
|
56 |
131 |
1.47e-2 |
SMART |
|
CA
|
155 |
240 |
1.23e-19 |
SMART |
|
CA
|
264 |
343 |
5.54e-27 |
SMART |
|
CA
|
367 |
448 |
5.09e-26 |
SMART |
|
CA
|
472 |
558 |
1.98e-23 |
SMART |
|
CA
|
589 |
670 |
1.3e-9 |
SMART |
|
transmembrane domain
|
689 |
711 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
912 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195823
|
| SMART Domains |
Protein: ENSMUSP00000141803
Gene: ENSMUSG00000103793
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
24 |
N/A |
INTRINSIC |
|
CA
|
45 |
131 |
2.41e-2 |
SMART |
|
CA
|
155 |
240 |
5.77e-16 |
SMART |
|
CA
|
264 |
345 |
1.1e-21 |
SMART |
|
CA
|
369 |
450 |
2.75e-22 |
SMART |
|
low complexity region
|
453 |
462 |
N/A |
INTRINSIC |
|
CA
|
474 |
560 |
9.22e-24 |
SMART |
|
CA
|
591 |
669 |
2.4e-13 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
932 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 61 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aasdhppt |
A |
G |
9: 4,308,732 (GRCm39) |
V124A |
probably benign |
Het |
| Abca4 |
A |
G |
3: 121,904,186 (GRCm39) |
M746V |
possibly damaging |
Het |
| Aldh18a1 |
G |
T |
19: 40,562,226 (GRCm39) |
S266* |
probably null |
Het |
| Aldh1b1 |
C |
A |
4: 45,802,968 (GRCm39) |
H169N |
probably benign |
Het |
| Anpep |
A |
G |
7: 79,476,709 (GRCm39) |
I756T |
possibly damaging |
Het |
| Asb16 |
A |
T |
11: 102,168,739 (GRCm39) |
E405V |
probably benign |
Het |
| B4galnt1 |
T |
A |
10: 127,007,490 (GRCm39) |
F464I |
probably damaging |
Het |
| Bpifb5 |
A |
G |
2: 154,070,975 (GRCm39) |
I225V |
probably benign |
Het |
| Brox |
T |
C |
1: 183,062,484 (GRCm39) |
E290G |
probably damaging |
Het |
| Cacna1s |
T |
A |
1: 136,020,333 (GRCm39) |
V790D |
possibly damaging |
Het |
| Cacng6 |
G |
T |
7: 3,473,384 (GRCm39) |
K69N |
possibly damaging |
Het |
| Catsperg1 |
A |
G |
7: 28,895,344 (GRCm39) |
I503T |
possibly damaging |
Het |
| Cdcp3 |
A |
G |
7: 130,852,205 (GRCm39) |
N814D |
probably damaging |
Het |
| Celsr3 |
A |
C |
9: 108,706,840 (GRCm39) |
M1108L |
probably benign |
Het |
| Chd2 |
T |
C |
7: 73,149,373 (GRCm39) |
N449S |
probably benign |
Het |
| Cpne6 |
T |
C |
14: 55,750,066 (GRCm39) |
C66R |
possibly damaging |
Het |
| Ctnna2 |
T |
C |
6: 76,919,270 (GRCm39) |
E656G |
probably damaging |
Het |
| Dnah17 |
A |
T |
11: 118,018,048 (GRCm39) |
M149K |
probably benign |
Het |
| Dpp8 |
A |
T |
9: 64,944,262 (GRCm39) |
M10L |
possibly damaging |
Het |
| Dst |
T |
C |
1: 34,329,486 (GRCm39) |
L4838P |
probably damaging |
Het |
| Eif4g3 |
T |
A |
4: 137,824,082 (GRCm39) |
I55N |
probably damaging |
Het |
| Gm10750 |
A |
G |
2: 148,858,017 (GRCm39) |
L78P |
unknown |
Het |
| Gulo |
T |
G |
14: 66,237,288 (GRCm39) |
K200Q |
probably benign |
Het |
| Jmjd8 |
T |
A |
17: 26,048,071 (GRCm39) |
L56Q |
probably benign |
Het |
| Kansl1 |
G |
T |
11: 104,315,112 (GRCm39) |
Q309K |
probably damaging |
Het |
| Kcns3 |
A |
C |
12: 11,141,718 (GRCm39) |
L327R |
probably damaging |
Het |
| Mapk10 |
A |
G |
5: 103,139,792 (GRCm39) |
I153T |
possibly damaging |
Het |
| Muc5b |
G |
T |
7: 141,400,569 (GRCm39) |
M513I |
unknown |
Het |
| Nbea |
A |
G |
3: 55,966,086 (GRCm39) |
F459L |
probably damaging |
Het |
| Nrcam |
G |
A |
12: 44,631,644 (GRCm39) |
V1066I |
possibly damaging |
Het |
| Numa1 |
A |
G |
7: 101,651,538 (GRCm39) |
K178E |
probably damaging |
Het |
| Or4b1 |
C |
T |
2: 89,979,928 (GRCm39) |
V141M |
probably benign |
Het |
| Or5au1 |
T |
C |
14: 52,272,645 (GRCm39) |
K308E |
probably benign |
Het |
| Or5d14 |
G |
A |
2: 87,880,290 (GRCm39) |
T226M |
probably damaging |
Het |
| Pabpc4 |
C |
T |
4: 123,191,837 (GRCm39) |
A649V |
probably benign |
Het |
| Parp12 |
C |
A |
6: 39,079,612 (GRCm39) |
K299N |
possibly damaging |
Het |
| Polr2a |
T |
C |
11: 69,638,330 (GRCm39) |
T79A |
probably benign |
Het |
| Ppp1r7 |
T |
C |
1: 93,273,904 (GRCm39) |
S27P |
probably damaging |
Het |
| Pramel42 |
G |
T |
5: 94,685,440 (GRCm39) |
D367Y |
probably damaging |
Het |
| Prol1 |
T |
G |
5: 88,475,874 (GRCm39) |
L88R |
probably damaging |
Het |
| Ptpn6 |
T |
C |
6: 124,709,425 (GRCm39) |
Q57R |
possibly damaging |
Het |
| Rdh16 |
A |
G |
10: 127,637,334 (GRCm39) |
I90V |
probably benign |
Het |
| Rock2 |
T |
A |
12: 16,998,558 (GRCm39) |
C275S |
probably damaging |
Het |
| Rp1l1 |
G |
T |
14: 64,268,674 (GRCm39) |
R1420L |
probably damaging |
Het |
| Sav1 |
A |
G |
12: 70,033,481 (GRCm39) |
Y21H |
probably damaging |
Het |
| Sec24a |
T |
C |
11: 51,612,749 (GRCm39) |
N536S |
probably benign |
Het |
| Serpina9 |
A |
C |
12: 103,964,421 (GRCm39) |
F339V |
probably damaging |
Het |
| Slc6a13 |
T |
G |
6: 121,311,450 (GRCm39) |
L369V |
possibly damaging |
Het |
| Smarcd3 |
A |
T |
5: 24,801,024 (GRCm39) |
F128I |
probably damaging |
Het |
| Smok2a |
A |
T |
17: 13,444,599 (GRCm39) |
I59F |
probably damaging |
Het |
| Spaca9 |
A |
G |
2: 28,583,634 (GRCm39) |
|
probably null |
Het |
| Ssx2ip |
A |
T |
3: 146,124,928 (GRCm39) |
E84D |
probably benign |
Het |
| Syt12 |
A |
T |
19: 4,497,830 (GRCm39) |
V384E |
probably benign |
Het |
| Ticrr |
T |
A |
7: 79,331,584 (GRCm39) |
L727Q |
probably damaging |
Het |
| Tmem170b |
A |
G |
13: 41,781,463 (GRCm39) |
Y36C |
probably damaging |
Het |
| Tpd52l1 |
T |
C |
10: 31,214,201 (GRCm39) |
T161A |
probably damaging |
Het |
| Zan |
T |
A |
5: 137,461,841 (GRCm39) |
T1113S |
unknown |
Het |
| Zfp512b |
T |
C |
2: 181,231,689 (GRCm39) |
T164A |
probably damaging |
Het |
| Zfp521 |
G |
A |
18: 13,977,549 (GRCm39) |
P955S |
probably damaging |
Het |
| Zfp770 |
C |
T |
2: 114,027,305 (GRCm39) |
V255I |
probably benign |
Het |
| Zfp942 |
A |
T |
17: 22,148,208 (GRCm39) |
C140* |
probably null |
Het |
|
| Other mutations in Pcdhga7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
micro
|
UTSW |
18 |
37,850,327 (GRCm39) |
missense |
probably benign |
0.04 |
|
milli
|
UTSW |
18 |
37,849,483 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3012:Pcdhga7
|
UTSW |
18 |
37,848,691 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3950:Pcdhga7
|
UTSW |
18 |
37,849,568 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4697:Pcdhga7
|
UTSW |
18 |
37,850,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4985:Pcdhga7
|
UTSW |
18 |
37,848,698 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5073:Pcdhga7
|
UTSW |
18 |
37,849,025 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5137:Pcdhga7
|
UTSW |
18 |
37,850,433 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5424:Pcdhga7
|
UTSW |
18 |
37,848,388 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5534:Pcdhga7
|
UTSW |
18 |
37,849,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5619:Pcdhga7
|
UTSW |
18 |
37,848,800 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5689:Pcdhga7
|
UTSW |
18 |
37,849,736 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6200:Pcdhga7
|
UTSW |
18 |
37,849,135 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6235:Pcdhga7
|
UTSW |
18 |
37,849,483 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6597:Pcdhga7
|
UTSW |
18 |
37,850,059 (GRCm39) |
missense |
probably benign |
0.24 |
|
R6684:Pcdhga7
|
UTSW |
18 |
37,849,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6714:Pcdhga7
|
UTSW |
18 |
37,850,330 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6810:Pcdhga7
|
UTSW |
18 |
37,848,926 (GRCm39) |
missense |
probably benign |
0.24 |
|
R6920:Pcdhga7
|
UTSW |
18 |
37,848,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6922:Pcdhga7
|
UTSW |
18 |
37,848,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7051:Pcdhga7
|
UTSW |
18 |
37,849,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7072:Pcdhga7
|
UTSW |
18 |
37,850,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7265:Pcdhga7
|
UTSW |
18 |
37,849,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7397:Pcdhga7
|
UTSW |
18 |
37,850,327 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7450:Pcdhga7
|
UTSW |
18 |
37,849,079 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7451:Pcdhga7
|
UTSW |
18 |
37,849,057 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7790:Pcdhga7
|
UTSW |
18 |
37,847,996 (GRCm39) |
start codon destroyed |
probably null |
0.85 |
|
R7833:Pcdhga7
|
UTSW |
18 |
37,849,077 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7922:Pcdhga7
|
UTSW |
18 |
37,849,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8007:Pcdhga7
|
UTSW |
18 |
37,849,946 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8073:Pcdhga7
|
UTSW |
18 |
37,848,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8724:Pcdhga7
|
UTSW |
18 |
37,848,146 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8962:Pcdhga7
|
UTSW |
18 |
37,848,879 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9191:Pcdhga7
|
UTSW |
18 |
37,848,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9684:Pcdhga7
|
UTSW |
18 |
37,848,667 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACGTCCCGGAGAACAATCC -3'
(R):5'- GAGTCTTTGTCCACAGCTACC -3'
Sequencing Primer
(F):5'- CCAGAGGAGCCTCCATCTTC -3'
(R):5'- CACTAGGTATCCAGGTTCTGCAGAG -3'
|
| Posted On |
2020-09-15 |
Incidental Mutation