Incidental Mutation 'R7960:Ablim2'
| ID |
650043 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ablim2
|
| Ensembl Gene |
ENSMUSG00000029095 |
| Gene Name |
actin-binding LIM protein 2 |
| Synonyms |
|
| MMRRC Submission |
046004-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.156)
|
| Stock # |
R7960 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
35915224-36042317 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 36014493 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Alanine
at position 450
(E450A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000050571
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000054598]
[ENSMUST00000101280]
[ENSMUST00000114203]
[ENSMUST00000114204]
[ENSMUST00000114205]
[ENSMUST00000114206]
[ENSMUST00000114210]
[ENSMUST00000129347]
|
| AlphaFold |
Q8BL65 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054598
AA Change: E450A
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000050571
Gene: ENSMUSG00000029095
AA Change: E450A
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
477 |
489 |
N/A |
INTRINSIC |
|
VHP
|
577 |
612 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101280
AA Change: E484A
PolyPhen 2
Score 0.321 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000098838
Gene: ENSMUSG00000029095
AA Change: E484A
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
297 |
315 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
392 |
N/A |
INTRINSIC |
|
low complexity region
|
511 |
523 |
N/A |
INTRINSIC |
|
VHP
|
572 |
607 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114203
AA Change: E184A
PolyPhen 2
Score 0.156 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000109841
Gene: ENSMUSG00000029095
AA Change: E184A
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1WIG|A
|
1 |
28 |
5e-13 |
PDB |
|
low complexity region
|
35 |
53 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
141 |
N/A |
INTRINSIC |
|
low complexity region
|
211 |
223 |
N/A |
INTRINSIC |
|
VHP
|
311 |
346 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114204
AA Change: E483A
PolyPhen 2
Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000109842
Gene: ENSMUSG00000029095
AA Change: E483A
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
510 |
522 |
N/A |
INTRINSIC |
|
VHP
|
571 |
606 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114205
AA Change: E450A
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000109843
Gene: ENSMUSG00000029095
AA Change: E450A
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
477 |
489 |
N/A |
INTRINSIC |
|
VHP
|
538 |
573 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114206
AA Change: E494A
PolyPhen 2
Score 0.275 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000109844
Gene: ENSMUSG00000029095
AA Change: E494A
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
521 |
533 |
N/A |
INTRINSIC |
|
VHP
|
582 |
617 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114210
AA Change: E483A
PolyPhen 2
Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000109848
Gene: ENSMUSG00000029095
AA Change: E483A
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
510 |
522 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000115931
Gene: ENSMUSG00000029095
AA Change: E108A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AbLIM_anchor
|
1 |
115 |
6.3e-29 |
PFAM |
|
low complexity region
|
136 |
148 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129347
AA Change: E502A
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000123525
Gene: ENSMUSG00000029095
AA Change: E502A
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
Pfam:AbLIM_anchor
|
295 |
513 |
2.1e-78 |
PFAM |
|
Pfam:AbLIM_anchor
|
497 |
628 |
2.6e-37 |
PFAM |
|
VHP
|
629 |
664 |
2.34e-19 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000114616
Gene: ENSMUSG00000029095
AA Change: E173A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AbLIM_anchor
|
12 |
164 |
4.3e-55 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123616
Gene: ENSMUSG00000029095
AA Change: E143A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AbLIM_anchor
|
22 |
148 |
5.6e-54 |
PFAM |
|
low complexity region
|
171 |
183 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153529
|
| SMART Domains |
Protein: ENSMUSP00000118019
Gene: ENSMUSG00000029095
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AbLIM_anchor
|
43 |
73 |
1.7e-17 |
PFAM |
|
VHP
|
74 |
109 |
2.34e-19 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (71/72) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110004F10Rik |
T |
C |
7: 115,702,481 (GRCm39) |
S82P |
possibly damaging |
Het |
| Acacb |
G |
T |
5: 114,368,922 (GRCm39) |
M1713I |
probably benign |
Het |
| Acbd6 |
C |
A |
1: 155,562,766 (GRCm39) |
Q256K |
probably benign |
Het |
| Agbl2 |
A |
T |
2: 90,621,975 (GRCm39) |
N154I |
probably benign |
Het |
| Ahcyl2 |
A |
G |
6: 29,870,626 (GRCm39) |
N181D |
probably benign |
Het |
| Aldh18a1 |
A |
T |
19: 40,546,264 (GRCm39) |
D544E |
probably benign |
Het |
| Anapc1 |
A |
T |
2: 128,516,513 (GRCm39) |
L407Q |
probably damaging |
Het |
| Arhgap26 |
T |
A |
18: 39,362,980 (GRCm39) |
V34D |
|
Het |
| Brd3 |
A |
T |
2: 27,342,945 (GRCm39) |
S516T |
probably benign |
Het |
| Bsn |
A |
G |
9: 107,992,747 (GRCm39) |
S1002P |
probably damaging |
Het |
| C4b |
G |
T |
17: 34,960,252 (GRCm39) |
|
probably null |
Het |
| Camta1 |
T |
C |
4: 151,232,990 (GRCm39) |
T228A |
probably benign |
Het |
| Cct6b |
T |
C |
11: 82,632,221 (GRCm39) |
K256E |
possibly damaging |
Het |
| Cep85l |
T |
A |
10: 53,172,403 (GRCm39) |
Q552L |
probably benign |
Het |
| Col6a5 |
A |
G |
9: 105,823,049 (GRCm39) |
F103L |
unknown |
Het |
| Copb2 |
A |
G |
9: 98,462,407 (GRCm39) |
Q464R |
possibly damaging |
Het |
| Dlc1 |
G |
T |
8: 37,404,989 (GRCm39) |
H267N |
probably benign |
Het |
| Dnajb2 |
T |
C |
1: 75,218,055 (GRCm39) |
I184T |
|
Het |
| Dnajc9 |
C |
T |
14: 20,438,764 (GRCm39) |
E30K |
possibly damaging |
Het |
| Dock1 |
T |
C |
7: 134,678,917 (GRCm39) |
L1012P |
possibly damaging |
Het |
| Dtnbp1 |
T |
C |
13: 45,106,650 (GRCm39) |
K170R |
probably benign |
Het |
| F13b |
T |
A |
1: 139,431,509 (GRCm39) |
C26* |
probably null |
Het |
| Ficd |
G |
T |
5: 113,877,020 (GRCm39) |
E398D |
probably benign |
Het |
| G6pc1 |
G |
A |
11: 101,267,359 (GRCm39) |
G270R |
probably damaging |
Het |
| Garin4 |
T |
A |
1: 190,895,645 (GRCm39) |
T333S |
probably benign |
Het |
| Gm3604 |
T |
C |
13: 62,517,587 (GRCm39) |
Y257C |
probably damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,531,606 (GRCm39) |
Y3221F |
probably damaging |
Het |
| Hs3st3b1 |
C |
T |
11: 63,812,694 (GRCm39) |
G7D |
possibly damaging |
Het |
| Htr3b |
A |
T |
9: 48,856,852 (GRCm39) |
S209T |
probably benign |
Het |
| Ift70a1 |
A |
T |
2: 75,811,188 (GRCm39) |
D298E |
probably benign |
Het |
| Iglon5 |
T |
A |
7: 43,126,326 (GRCm39) |
E192D |
probably benign |
Het |
| Inpp5f |
A |
G |
7: 128,295,638 (GRCm39) |
|
probably null |
Het |
| Kif26b |
T |
A |
1: 178,506,484 (GRCm39) |
C187S |
probably damaging |
Het |
| Klhl11 |
A |
G |
11: 100,354,805 (GRCm39) |
S339P |
probably benign |
Het |
| Klk14 |
G |
A |
7: 43,341,467 (GRCm39) |
A40T |
probably damaging |
Het |
| Kmt2c |
G |
A |
5: 25,520,194 (GRCm39) |
T1972I |
probably benign |
Het |
| Lama2 |
T |
C |
10: 26,869,094 (GRCm39) |
T2784A |
probably benign |
Het |
| Loxhd1 |
T |
A |
18: 77,472,746 (GRCm39) |
F1088I |
probably damaging |
Het |
| Map2k2 |
G |
A |
10: 80,954,968 (GRCm39) |
R185Q |
probably benign |
Het |
| Mbd5 |
G |
A |
2: 49,169,796 (GRCm39) |
|
probably null |
Het |
| Mdc1 |
A |
T |
17: 36,161,570 (GRCm39) |
R828* |
probably null |
Het |
| Nrp2 |
C |
T |
1: 62,784,567 (GRCm39) |
R239C |
probably damaging |
Het |
| Or5g25 |
A |
G |
2: 85,478,417 (GRCm39) |
S83P |
possibly damaging |
Het |
| Parp4 |
C |
A |
14: 56,832,708 (GRCm39) |
|
probably null |
Het |
| Pbk |
T |
A |
14: 66,046,650 (GRCm39) |
|
probably null |
Het |
| Phip |
A |
T |
9: 82,775,401 (GRCm39) |
D1060E |
probably benign |
Het |
| Pik3c2b |
T |
A |
1: 133,031,587 (GRCm39) |
L1509Q |
probably damaging |
Het |
| Pik3r5 |
T |
A |
11: 68,386,796 (GRCm39) |
F808L |
probably benign |
Het |
| Plcl1 |
T |
A |
1: 55,736,443 (GRCm39) |
S595T |
possibly damaging |
Het |
| Plxna2 |
AT |
A |
1: 194,476,172 (GRCm39) |
|
probably null |
Het |
| Pole |
A |
G |
5: 110,437,727 (GRCm39) |
K95R |
possibly damaging |
Het |
| Poteg |
A |
G |
8: 27,946,888 (GRCm39) |
T259A |
probably benign |
Het |
| Pramel52-ps |
A |
G |
5: 94,531,739 (GRCm39) |
M208V |
probably benign |
Het |
| Ptpn12 |
G |
T |
5: 21,260,687 (GRCm39) |
P20Q |
probably benign |
Het |
| Ptpn5 |
T |
A |
7: 46,729,295 (GRCm39) |
T440S |
possibly damaging |
Het |
| Ptpru |
T |
C |
4: 131,515,820 (GRCm39) |
R845G |
probably benign |
Het |
| Rasgrp2 |
G |
T |
19: 6,464,839 (GRCm39) |
V596L |
probably benign |
Het |
| Rcbtb2 |
T |
G |
14: 73,399,384 (GRCm39) |
V16G |
probably benign |
Het |
| Rel |
T |
C |
11: 23,694,493 (GRCm39) |
N289S |
probably damaging |
Het |
| Rpn1 |
T |
A |
6: 88,079,068 (GRCm39) |
Y504N |
probably damaging |
Het |
| Rsf1 |
CGGCGGCGG |
CGGCGGCGGGGGCGGCGG |
7: 97,229,124 (GRCm39) |
|
probably benign |
Het |
| Scaf8 |
G |
A |
17: 3,221,397 (GRCm39) |
V295M |
unknown |
Het |
| Skic3 |
T |
C |
13: 76,260,318 (GRCm39) |
C87R |
probably benign |
Het |
| Slc25a48 |
T |
A |
13: 56,611,411 (GRCm39) |
Y173N |
probably damaging |
Het |
| Slc8a3 |
C |
T |
12: 81,263,506 (GRCm39) |
S627N |
probably benign |
Het |
| Snx8 |
T |
A |
5: 140,343,848 (GRCm39) |
M123L |
probably benign |
Het |
| Sri |
A |
T |
5: 8,114,586 (GRCm39) |
Q180H |
probably benign |
Het |
| Sycp2 |
T |
A |
2: 178,046,453 (GRCm39) |
R4S |
probably null |
Het |
| Tcstv1a |
G |
A |
13: 120,355,521 (GRCm39) |
T37I |
possibly damaging |
Het |
| Tnnc2 |
A |
T |
2: 164,619,704 (GRCm39) |
D87E |
probably benign |
Het |
| Trim7 |
A |
T |
11: 48,728,628 (GRCm39) |
N92I |
probably damaging |
Het |
| Trpv6 |
C |
T |
6: 41,604,612 (GRCm39) |
D97N |
probably benign |
Het |
| Ulk4 |
A |
G |
9: 121,102,022 (GRCm39) |
Y19H |
probably damaging |
Het |
| Vmn2r69 |
C |
T |
7: 85,055,973 (GRCm39) |
V722I |
probably benign |
Het |
| Zan |
T |
C |
5: 137,407,865 (GRCm39) |
D3643G |
unknown |
Het |
| Zan |
G |
A |
5: 137,463,154 (GRCm39) |
T675I |
unknown |
Het |
|
| Other mutations in Ablim2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00939:Ablim2
|
APN |
5 |
35,981,359 (GRCm39) |
unclassified |
probably benign |
|
|
IGL00945:Ablim2
|
APN |
5 |
35,994,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02439:Ablim2
|
APN |
5 |
36,015,206 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02664:Ablim2
|
APN |
5 |
36,006,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02897:Ablim2
|
APN |
5 |
35,990,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03034:Ablim2
|
APN |
5 |
35,985,509 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03096:Ablim2
|
APN |
5 |
36,040,743 (GRCm39) |
nonsense |
probably null |
|
|
IGL03384:Ablim2
|
APN |
5 |
36,032,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0128:Ablim2
|
UTSW |
5 |
35,966,520 (GRCm39) |
splice site |
probably benign |
|
|
R0130:Ablim2
|
UTSW |
5 |
35,966,520 (GRCm39) |
splice site |
probably benign |
|
|
R0212:Ablim2
|
UTSW |
5 |
36,006,254 (GRCm39) |
splice site |
probably null |
|
|
R0344:Ablim2
|
UTSW |
5 |
35,994,277 (GRCm39) |
splice site |
probably benign |
|
|
R0675:Ablim2
|
UTSW |
5 |
36,024,124 (GRCm39) |
splice site |
probably benign |
|
|
R0788:Ablim2
|
UTSW |
5 |
36,015,245 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1148:Ablim2
|
UTSW |
5 |
35,966,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Ablim2
|
UTSW |
5 |
35,966,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1493:Ablim2
|
UTSW |
5 |
35,966,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Ablim2
|
UTSW |
5 |
36,000,614 (GRCm39) |
intron |
probably benign |
|
|
R2070:Ablim2
|
UTSW |
5 |
35,955,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2163:Ablim2
|
UTSW |
5 |
35,959,697 (GRCm39) |
splice site |
probably benign |
|
|
R3962:Ablim2
|
UTSW |
5 |
35,969,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4852:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4853:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4854:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4855:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4866:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4867:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4906:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4908:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4909:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4927:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5210:Ablim2
|
UTSW |
5 |
35,994,416 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5225:Ablim2
|
UTSW |
5 |
36,024,115 (GRCm39) |
splice site |
probably null |
|
|
R5439:Ablim2
|
UTSW |
5 |
36,015,170 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5528:Ablim2
|
UTSW |
5 |
36,013,510 (GRCm39) |
nonsense |
probably null |
|
|
R5629:Ablim2
|
UTSW |
5 |
36,014,507 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5653:Ablim2
|
UTSW |
5 |
36,040,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Ablim2
|
UTSW |
5 |
35,969,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6059:Ablim2
|
UTSW |
5 |
36,014,508 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6241:Ablim2
|
UTSW |
5 |
36,032,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7492:Ablim2
|
UTSW |
5 |
35,998,673 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7562:Ablim2
|
UTSW |
5 |
36,030,563 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8414:Ablim2
|
UTSW |
5 |
36,032,235 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8557:Ablim2
|
UTSW |
5 |
35,985,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8690:Ablim2
|
UTSW |
5 |
36,030,518 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8710:Ablim2
|
UTSW |
5 |
36,030,518 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8713:Ablim2
|
UTSW |
5 |
36,030,518 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R9059:Ablim2
|
UTSW |
5 |
35,959,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9452:Ablim2
|
UTSW |
5 |
36,015,198 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9622:Ablim2
|
UTSW |
5 |
36,006,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ablim2
|
UTSW |
5 |
36,006,202 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
Z1177:Ablim2
|
UTSW |
5 |
35,998,637 (GRCm39) |
small deletion |
probably benign |
|
|
Z1177:Ablim2
|
UTSW |
5 |
35,981,387 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1188:Ablim2
|
UTSW |
5 |
35,994,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGTGTCATTCCTCCAGC -3'
(R):5'- GTATCTCCTCAGTCCCAGAACC -3'
Sequencing Primer
(F):5'- ATTCCTCCAGCCTGTGAAAG -3'
(R):5'- GCAGAGCATGTGCCCATACAG -3'
|
| Posted On |
2020-09-15 |
Incidental Mutation