Incidental Mutation 'R7980:Ift172'
| ID |
651131 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ift172
|
| Ensembl Gene |
ENSMUSG00000038564 |
| Gene Name |
intraflagellar transport 172 |
| Synonyms |
4930553F24Rik, wim, avc1 |
| MMRRC Submission |
046021-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7980 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
31410623-31448458 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 31417988 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Valine
at position 1267
(E1267V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041565]
|
| AlphaFold |
Q6VH22 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041565
AA Change: E1267V
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000049335
Gene: ENSMUSG00000038564
AA Change: E1267V
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
44 |
6e-3 |
SMART |
|
WD40
|
55 |
94 |
2.22e0 |
SMART |
|
WD40
|
102 |
139 |
1.23e2 |
SMART |
|
WD40
|
141 |
180 |
4.6e0 |
SMART |
|
WD40
|
186 |
223 |
3.3e1 |
SMART |
|
WD40
|
225 |
267 |
4.42e1 |
SMART |
|
WD40
|
279 |
314 |
1.03e1 |
SMART |
|
Blast:WD40
|
516 |
550 |
5e-13 |
BLAST |
|
low complexity region
|
573 |
588 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
625 |
1026 |
1.7e-10 |
PROSPERO |
|
Blast:TPR
|
1029 |
1062 |
2e-13 |
BLAST |
|
low complexity region
|
1077 |
1091 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1101 |
1498 |
1.7e-10 |
PROSPERO |
|
| Meta Mutation Damage Score |
0.0737 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014]
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality during organogenesis, neural tube defects, and developmental patterning abnormalities. Mice homozygous for a conditional allele activated in the early limb bud exhibit polydactyly and short limbs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930553M12Rik |
A |
G |
4: 88,786,315 (GRCm39) |
L101P |
unknown |
Het |
| Actn3 |
G |
A |
19: 4,917,950 (GRCm39) |
P339L |
probably damaging |
Het |
| Adamts12 |
G |
A |
15: 11,263,423 (GRCm39) |
C595Y |
probably damaging |
Het |
| Adrm1b |
T |
A |
3: 92,336,406 (GRCm39) |
K99* |
probably null |
Het |
| Agl |
A |
T |
3: 116,585,830 (GRCm39) |
N99K |
probably benign |
Het |
| Aplp1 |
A |
T |
7: 30,134,992 (GRCm39) |
M592K |
probably benign |
Het |
| Arhgef11 |
C |
T |
3: 87,605,297 (GRCm39) |
R251C |
probably benign |
Het |
| Arhgef12 |
A |
T |
9: 42,882,595 (GRCm39) |
C1416* |
probably null |
Het |
| Asah1 |
A |
G |
8: 41,807,067 (GRCm39) |
M119T |
|
Het |
| Asxl2 |
A |
T |
12: 3,546,630 (GRCm39) |
Q471H |
probably damaging |
Het |
| Atp6v1c2 |
A |
T |
12: 17,371,613 (GRCm39) |
D61E |
probably damaging |
Het |
| Btbd16 |
C |
A |
7: 130,426,097 (GRCm39) |
P520Q |
probably damaging |
Het |
| Cacnb2 |
A |
G |
2: 14,609,326 (GRCm39) |
E22G |
probably benign |
Het |
| Catspere2 |
G |
T |
1: 177,830,610 (GRCm39) |
|
probably null |
Het |
| Cdc25a |
T |
A |
9: 109,708,949 (GRCm39) |
D124E |
probably damaging |
Het |
| Cdc42se1 |
A |
T |
3: 95,139,166 (GRCm39) |
|
probably benign |
Het |
| Cdcp3 |
T |
A |
7: 130,836,506 (GRCm39) |
V400E |
probably damaging |
Het |
| Cfap54 |
T |
C |
10: 92,817,922 (GRCm39) |
K1265E |
possibly damaging |
Het |
| Chaf1b |
A |
G |
16: 93,681,415 (GRCm39) |
H11R |
probably damaging |
Het |
| Chil4 |
T |
C |
3: 106,110,060 (GRCm39) |
K345E |
probably damaging |
Het |
| Cntnap1 |
A |
G |
11: 101,079,719 (GRCm39) |
I1283V |
probably benign |
Het |
| Dagla |
C |
T |
19: 10,229,406 (GRCm39) |
C618Y |
possibly damaging |
Het |
| Ddx19b |
C |
T |
8: 111,738,077 (GRCm39) |
V224M |
possibly damaging |
Het |
| Dohh |
C |
T |
10: 81,223,726 (GRCm39) |
R260* |
probably null |
Het |
| Dsg3 |
A |
T |
18: 20,664,417 (GRCm39) |
N472Y |
probably benign |
Het |
| Duox1 |
T |
A |
2: 122,177,801 (GRCm39) |
N1528K |
possibly damaging |
Het |
| Eml6 |
A |
G |
11: 29,783,205 (GRCm39) |
Y559H |
probably damaging |
Het |
| Esp4 |
A |
G |
17: 40,913,192 (GRCm39) |
T20A |
possibly damaging |
Het |
| Fbxw21 |
T |
C |
9: 108,985,639 (GRCm39) |
|
probably null |
Het |
| Gcc2 |
T |
A |
10: 58,114,574 (GRCm39) |
|
probably null |
Het |
| Grin3b |
C |
T |
10: 79,811,559 (GRCm39) |
A715V |
possibly damaging |
Het |
| Gxylt2 |
A |
T |
6: 100,764,170 (GRCm39) |
|
probably null |
Het |
| Hspa4 |
A |
T |
11: 53,171,404 (GRCm39) |
S267T |
probably benign |
Het |
| Hspd1 |
A |
G |
1: 55,117,785 (GRCm39) |
V491A |
possibly damaging |
Het |
| Idua |
A |
G |
5: 108,828,486 (GRCm39) |
E280G |
probably benign |
Het |
| Itsn1 |
T |
A |
16: 91,702,182 (GRCm39) |
V1448E |
unknown |
Het |
| Kat6a |
A |
G |
8: 23,416,432 (GRCm39) |
M647V |
possibly damaging |
Het |
| Kcnq4 |
A |
T |
4: 120,568,494 (GRCm39) |
D407E |
probably benign |
Het |
| Kif1b |
A |
T |
4: 149,354,378 (GRCm39) |
F221I |
probably damaging |
Het |
| Lama2 |
G |
T |
10: 27,239,609 (GRCm39) |
D315E |
probably damaging |
Het |
| Lrrn4 |
G |
A |
2: 132,720,096 (GRCm39) |
L235F |
probably damaging |
Het |
| Map2k6 |
T |
A |
11: 110,390,210 (GRCm39) |
I248N |
|
Het |
| Mgat5 |
A |
G |
1: 127,407,248 (GRCm39) |
Q638R |
probably benign |
Het |
| Mia2 |
A |
G |
12: 59,155,651 (GRCm39) |
K455E |
probably damaging |
Het |
| Mrs2 |
A |
G |
13: 25,204,221 (GRCm39) |
C3R |
possibly damaging |
Het |
| Nprl3 |
A |
G |
11: 32,187,357 (GRCm39) |
I325T |
probably damaging |
Het |
| Nr1h3 |
T |
A |
2: 91,021,229 (GRCm39) |
Q186L |
probably benign |
Het |
| Oas1f |
A |
G |
5: 120,989,538 (GRCm39) |
E159G |
probably benign |
Het |
| Or2g7 |
A |
T |
17: 38,378,412 (GRCm39) |
M117L |
possibly damaging |
Het |
| Or4k15b |
T |
A |
14: 50,272,252 (GRCm39) |
S203C |
probably damaging |
Het |
| Or52ae7 |
T |
A |
7: 103,119,504 (GRCm39) |
F86Y |
probably damaging |
Het |
| Or52e19b |
T |
A |
7: 103,032,970 (GRCm39) |
I80F |
probably damaging |
Het |
| Or52s1b |
T |
A |
7: 102,822,242 (GRCm39) |
S201C |
probably damaging |
Het |
| Or5m12 |
A |
G |
2: 85,734,942 (GRCm39) |
F152S |
probably benign |
Het |
| Or8g4 |
T |
C |
9: 39,662,417 (GRCm39) |
I245T |
probably damaging |
Het |
| Or9a4 |
T |
A |
6: 40,549,154 (GRCm39) |
I278N |
probably benign |
Het |
| Pbxip1 |
G |
C |
3: 89,353,648 (GRCm39) |
S267T |
probably benign |
Het |
| Pcdhga10 |
A |
T |
18: 37,881,645 (GRCm39) |
I469F |
possibly damaging |
Het |
| Pkd1l1 |
A |
G |
11: 8,804,375 (GRCm39) |
S1739P |
probably damaging |
Het |
| Plcd4 |
A |
C |
1: 74,604,464 (GRCm39) |
N788T |
probably benign |
Het |
| Pms2 |
T |
A |
5: 143,867,909 (GRCm39) |
W838R |
probably damaging |
Het |
| Pnpla6 |
T |
A |
8: 3,586,562 (GRCm39) |
V926D |
probably damaging |
Het |
| Pros1 |
A |
T |
16: 62,748,516 (GRCm39) |
H663L |
possibly damaging |
Het |
| Prss55 |
T |
C |
14: 64,316,138 (GRCm39) |
|
probably null |
Het |
| Pum2 |
T |
C |
12: 8,763,904 (GRCm39) |
Y283H |
probably damaging |
Het |
| Rad21 |
A |
G |
15: 51,828,422 (GRCm39) |
S549P |
probably benign |
Het |
| Sap130 |
T |
A |
18: 31,781,182 (GRCm39) |
|
probably null |
Het |
| Sertad4 |
C |
T |
1: 192,529,189 (GRCm39) |
S209N |
probably benign |
Het |
| Sez6 |
A |
G |
11: 77,844,668 (GRCm39) |
T164A |
probably benign |
Het |
| Slc22a28 |
C |
T |
19: 8,078,837 (GRCm39) |
R284Q |
probably damaging |
Het |
| Slco4c1 |
T |
C |
1: 96,764,650 (GRCm39) |
K474R |
probably benign |
Het |
| Stx5a |
T |
C |
19: 8,719,802 (GRCm39) |
S56P |
probably damaging |
Het |
| Svopl |
T |
C |
6: 37,991,744 (GRCm39) |
T379A |
probably damaging |
Het |
| Sypl2 |
A |
G |
3: 108,125,008 (GRCm39) |
F118L |
probably damaging |
Het |
| Tfrc |
G |
A |
16: 32,435,967 (GRCm39) |
V215M |
probably benign |
Het |
| Thnsl2 |
T |
C |
6: 71,115,652 (GRCm39) |
N185S |
probably damaging |
Het |
| Tmem104 |
T |
C |
11: 115,134,580 (GRCm39) |
I372T |
probably damaging |
Het |
| Tnfaip6 |
G |
A |
2: 51,941,070 (GRCm39) |
G204S |
probably damaging |
Het |
| Trim12a |
C |
T |
7: 103,953,335 (GRCm39) |
E259K |
probably benign |
Het |
| Tubgcp6 |
G |
A |
15: 88,986,232 (GRCm39) |
R1436C |
probably benign |
Het |
| Tyrp1 |
C |
T |
4: 80,758,864 (GRCm39) |
L246F |
probably damaging |
Het |
| Ubr4 |
G |
T |
4: 139,145,717 (GRCm39) |
V216F |
|
Het |
| Unc5a |
A |
G |
13: 55,147,319 (GRCm39) |
I409V |
possibly damaging |
Het |
| Vmn1r15 |
T |
C |
6: 57,235,399 (GRCm39) |
L89P |
probably damaging |
Het |
| Vmn1r32 |
A |
T |
6: 66,530,305 (GRCm39) |
L157* |
probably null |
Het |
| Zcchc24 |
A |
G |
14: 25,720,185 (GRCm39) |
Y160H |
probably damaging |
Het |
| Zfp184 |
A |
T |
13: 22,144,376 (GRCm39) |
H694L |
probably damaging |
Het |
| Zfp345 |
A |
C |
2: 150,314,723 (GRCm39) |
Y271* |
probably null |
Het |
| Zranb3 |
T |
C |
1: 128,030,671 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Ift172 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Ift172
|
APN |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01399:Ift172
|
APN |
5 |
31,423,592 (GRCm39) |
missense |
probably benign |
|
|
IGL01405:Ift172
|
APN |
5 |
31,419,196 (GRCm39) |
nonsense |
probably null |
|
|
IGL01562:Ift172
|
APN |
5 |
31,424,591 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01758:Ift172
|
APN |
5 |
31,438,058 (GRCm39) |
missense |
probably benign |
|
|
IGL01792:Ift172
|
APN |
5 |
31,434,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Ift172
|
APN |
5 |
31,442,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01839:Ift172
|
APN |
5 |
31,423,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02007:Ift172
|
APN |
5 |
31,443,948 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02172:Ift172
|
APN |
5 |
31,438,681 (GRCm39) |
splice site |
probably benign |
|
|
IGL02190:Ift172
|
APN |
5 |
31,411,802 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL02334:Ift172
|
APN |
5 |
31,440,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02486:Ift172
|
APN |
5 |
31,414,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02517:Ift172
|
APN |
5 |
31,410,992 (GRCm39) |
splice site |
probably null |
|
|
IGL02571:Ift172
|
APN |
5 |
31,415,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Ift172
|
APN |
5 |
31,421,840 (GRCm39) |
missense |
probably benign |
|
|
IGL03183:Ift172
|
APN |
5 |
31,429,348 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03277:Ift172
|
APN |
5 |
31,424,642 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03349:Ift172
|
APN |
5 |
31,441,474 (GRCm39) |
missense |
probably benign |
0.05 |
|
ostinato
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
pushback
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0042:Ift172
|
UTSW |
5 |
31,418,799 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4802001:Ift172
|
UTSW |
5 |
31,442,610 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0153:Ift172
|
UTSW |
5 |
31,417,968 (GRCm39) |
missense |
probably benign |
|
|
R0328:Ift172
|
UTSW |
5 |
31,421,195 (GRCm39) |
nonsense |
probably null |
|
|
R0357:Ift172
|
UTSW |
5 |
31,415,244 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R0369:Ift172
|
UTSW |
5 |
31,410,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0391:Ift172
|
UTSW |
5 |
31,444,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Ift172
|
UTSW |
5 |
31,442,821 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0546:Ift172
|
UTSW |
5 |
31,414,945 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0553:Ift172
|
UTSW |
5 |
31,433,186 (GRCm39) |
splice site |
probably benign |
|
|
R0606:Ift172
|
UTSW |
5 |
31,411,657 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0834:Ift172
|
UTSW |
5 |
31,414,715 (GRCm39) |
missense |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,415,262 (GRCm39) |
unclassified |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,422,699 (GRCm39) |
missense |
probably benign |
|
|
R1189:Ift172
|
UTSW |
5 |
31,443,174 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1205:Ift172
|
UTSW |
5 |
31,443,136 (GRCm39) |
missense |
probably benign |
|
|
R1289:Ift172
|
UTSW |
5 |
31,438,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1342:Ift172
|
UTSW |
5 |
31,419,210 (GRCm39) |
missense |
probably benign |
|
|
R1395:Ift172
|
UTSW |
5 |
31,442,582 (GRCm39) |
unclassified |
probably benign |
|
|
R1417:Ift172
|
UTSW |
5 |
31,413,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Ift172
|
UTSW |
5 |
31,424,585 (GRCm39) |
nonsense |
probably null |
|
|
R2111:Ift172
|
UTSW |
5 |
31,443,423 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2175:Ift172
|
UTSW |
5 |
31,424,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Ift172
|
UTSW |
5 |
31,420,312 (GRCm39) |
missense |
probably benign |
|
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3705:Ift172
|
UTSW |
5 |
31,418,781 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3793:Ift172
|
UTSW |
5 |
31,414,925 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4385:Ift172
|
UTSW |
5 |
31,444,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4477:Ift172
|
UTSW |
5 |
31,422,781 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4590:Ift172
|
UTSW |
5 |
31,411,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Ift172
|
UTSW |
5 |
31,441,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4665:Ift172
|
UTSW |
5 |
31,442,598 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4977:Ift172
|
UTSW |
5 |
31,429,460 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5109:Ift172
|
UTSW |
5 |
31,423,330 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5182:Ift172
|
UTSW |
5 |
31,424,958 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5343:Ift172
|
UTSW |
5 |
31,421,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5465:Ift172
|
UTSW |
5 |
31,418,862 (GRCm39) |
splice site |
probably null |
|
|
R5622:Ift172
|
UTSW |
5 |
31,440,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ift172
|
UTSW |
5 |
31,412,621 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5793:Ift172
|
UTSW |
5 |
31,434,292 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5870:Ift172
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5919:Ift172
|
UTSW |
5 |
31,418,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5968:Ift172
|
UTSW |
5 |
31,418,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Ift172
|
UTSW |
5 |
31,414,241 (GRCm39) |
missense |
probably benign |
|
|
R6339:Ift172
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6339:Ift172
|
UTSW |
5 |
31,413,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6355:Ift172
|
UTSW |
5 |
31,441,501 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6565:Ift172
|
UTSW |
5 |
31,433,227 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6668:Ift172
|
UTSW |
5 |
31,412,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6755:Ift172
|
UTSW |
5 |
31,418,342 (GRCm39) |
nonsense |
probably null |
|
|
R6818:Ift172
|
UTSW |
5 |
31,423,304 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6939:Ift172
|
UTSW |
5 |
31,414,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6980:Ift172
|
UTSW |
5 |
31,414,730 (GRCm39) |
missense |
probably benign |
|
|
R7047:Ift172
|
UTSW |
5 |
31,433,238 (GRCm39) |
nonsense |
probably null |
|
|
R7156:Ift172
|
UTSW |
5 |
31,429,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ift172
|
UTSW |
5 |
31,411,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Ift172
|
UTSW |
5 |
31,442,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7351:Ift172
|
UTSW |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7706:Ift172
|
UTSW |
5 |
31,423,723 (GRCm39) |
nonsense |
probably null |
|
|
R7890:Ift172
|
UTSW |
5 |
31,440,425 (GRCm39) |
nonsense |
probably null |
|
|
R8263:Ift172
|
UTSW |
5 |
31,422,681 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8559:Ift172
|
UTSW |
5 |
31,413,921 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8717:Ift172
|
UTSW |
5 |
31,412,985 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8774:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R8774-TAIL:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9037:Ift172
|
UTSW |
5 |
31,420,400 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9038:Ift172
|
UTSW |
5 |
31,441,399 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9133:Ift172
|
UTSW |
5 |
31,442,867 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9607:Ift172
|
UTSW |
5 |
31,410,913 (GRCm39) |
missense |
|
|
|
X0022:Ift172
|
UTSW |
5 |
31,442,664 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Ift172
|
UTSW |
5 |
31,434,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCCTGAGTCGCGAACTTTG -3'
(R):5'- AAGAAGTCTGTAGTCAGGCCAG -3'
Sequencing Primer
(F):5'- ACTTTGAGGTAGCAGTCCAC -3'
(R):5'- TCTGTAGTCAGGCCAGAGGAAC -3'
|
| Posted On |
2020-09-15 |
Incidental Mutation