Incidental Mutation 'R7980:Sez6'
| ID |
651163 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sez6
|
| Ensembl Gene |
ENSMUSG00000000632 |
| Gene Name |
seizure related gene 6 |
| Synonyms |
sez-6, D11Bhm177e |
| MMRRC Submission |
046021-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7980 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
77821626-77869874 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 77844668 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 164
(T164A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091532
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000000646]
[ENSMUST00000093995]
|
| AlphaFold |
Q7TSK2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000000646
AA Change: T164A
PolyPhen 2
Score 0.048 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000000646
Gene: ENSMUSG00000000632
AA Change: T164A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
910 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093995
AA Change: T164A
PolyPhen 2
Score 0.340 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000091532
Gene: ENSMUSG00000000632
AA Change: T164A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
923 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151982
|
| SMART Domains |
Protein: ENSMUSP00000132041
Gene: ENSMUSG00000000632
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
57 |
69 |
N/A |
INTRINSIC |
|
CUB
|
75 |
184 |
9.36e-2 |
SMART |
|
CCP
|
188 |
243 |
1.23e-10 |
SMART |
|
CUB
|
247 |
358 |
8.08e-29 |
SMART |
|
low complexity region
|
379 |
394 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0610 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit increased short dendrites, decreased excitatory synaptic signaling, resistance to pharmacologically induces seizures, decreased activity and impaired learning and coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930553M12Rik |
A |
G |
4: 88,786,315 (GRCm39) |
L101P |
unknown |
Het |
| Actn3 |
G |
A |
19: 4,917,950 (GRCm39) |
P339L |
probably damaging |
Het |
| Adamts12 |
G |
A |
15: 11,263,423 (GRCm39) |
C595Y |
probably damaging |
Het |
| Adrm1b |
T |
A |
3: 92,336,406 (GRCm39) |
K99* |
probably null |
Het |
| Agl |
A |
T |
3: 116,585,830 (GRCm39) |
N99K |
probably benign |
Het |
| Aplp1 |
A |
T |
7: 30,134,992 (GRCm39) |
M592K |
probably benign |
Het |
| Arhgef11 |
C |
T |
3: 87,605,297 (GRCm39) |
R251C |
probably benign |
Het |
| Arhgef12 |
A |
T |
9: 42,882,595 (GRCm39) |
C1416* |
probably null |
Het |
| Asah1 |
A |
G |
8: 41,807,067 (GRCm39) |
M119T |
|
Het |
| Asxl2 |
A |
T |
12: 3,546,630 (GRCm39) |
Q471H |
probably damaging |
Het |
| Atp6v1c2 |
A |
T |
12: 17,371,613 (GRCm39) |
D61E |
probably damaging |
Het |
| Btbd16 |
C |
A |
7: 130,426,097 (GRCm39) |
P520Q |
probably damaging |
Het |
| Cacnb2 |
A |
G |
2: 14,609,326 (GRCm39) |
E22G |
probably benign |
Het |
| Catspere2 |
G |
T |
1: 177,830,610 (GRCm39) |
|
probably null |
Het |
| Cdc25a |
T |
A |
9: 109,708,949 (GRCm39) |
D124E |
probably damaging |
Het |
| Cdc42se1 |
A |
T |
3: 95,139,166 (GRCm39) |
|
probably benign |
Het |
| Cdcp3 |
T |
A |
7: 130,836,506 (GRCm39) |
V400E |
probably damaging |
Het |
| Cfap54 |
T |
C |
10: 92,817,922 (GRCm39) |
K1265E |
possibly damaging |
Het |
| Chaf1b |
A |
G |
16: 93,681,415 (GRCm39) |
H11R |
probably damaging |
Het |
| Chil4 |
T |
C |
3: 106,110,060 (GRCm39) |
K345E |
probably damaging |
Het |
| Cntnap1 |
A |
G |
11: 101,079,719 (GRCm39) |
I1283V |
probably benign |
Het |
| Dagla |
C |
T |
19: 10,229,406 (GRCm39) |
C618Y |
possibly damaging |
Het |
| Ddx19b |
C |
T |
8: 111,738,077 (GRCm39) |
V224M |
possibly damaging |
Het |
| Dohh |
C |
T |
10: 81,223,726 (GRCm39) |
R260* |
probably null |
Het |
| Dsg3 |
A |
T |
18: 20,664,417 (GRCm39) |
N472Y |
probably benign |
Het |
| Duox1 |
T |
A |
2: 122,177,801 (GRCm39) |
N1528K |
possibly damaging |
Het |
| Eml6 |
A |
G |
11: 29,783,205 (GRCm39) |
Y559H |
probably damaging |
Het |
| Esp4 |
A |
G |
17: 40,913,192 (GRCm39) |
T20A |
possibly damaging |
Het |
| Fbxw21 |
T |
C |
9: 108,985,639 (GRCm39) |
|
probably null |
Het |
| Gcc2 |
T |
A |
10: 58,114,574 (GRCm39) |
|
probably null |
Het |
| Grin3b |
C |
T |
10: 79,811,559 (GRCm39) |
A715V |
possibly damaging |
Het |
| Gxylt2 |
A |
T |
6: 100,764,170 (GRCm39) |
|
probably null |
Het |
| Hspa4 |
A |
T |
11: 53,171,404 (GRCm39) |
S267T |
probably benign |
Het |
| Hspd1 |
A |
G |
1: 55,117,785 (GRCm39) |
V491A |
possibly damaging |
Het |
| Idua |
A |
G |
5: 108,828,486 (GRCm39) |
E280G |
probably benign |
Het |
| Ift172 |
T |
A |
5: 31,417,988 (GRCm39) |
E1267V |
probably benign |
Het |
| Itsn1 |
T |
A |
16: 91,702,182 (GRCm39) |
V1448E |
unknown |
Het |
| Kat6a |
A |
G |
8: 23,416,432 (GRCm39) |
M647V |
possibly damaging |
Het |
| Kcnq4 |
A |
T |
4: 120,568,494 (GRCm39) |
D407E |
probably benign |
Het |
| Kif1b |
A |
T |
4: 149,354,378 (GRCm39) |
F221I |
probably damaging |
Het |
| Lama2 |
G |
T |
10: 27,239,609 (GRCm39) |
D315E |
probably damaging |
Het |
| Lrrn4 |
G |
A |
2: 132,720,096 (GRCm39) |
L235F |
probably damaging |
Het |
| Map2k6 |
T |
A |
11: 110,390,210 (GRCm39) |
I248N |
|
Het |
| Mgat5 |
A |
G |
1: 127,407,248 (GRCm39) |
Q638R |
probably benign |
Het |
| Mia2 |
A |
G |
12: 59,155,651 (GRCm39) |
K455E |
probably damaging |
Het |
| Mrs2 |
A |
G |
13: 25,204,221 (GRCm39) |
C3R |
possibly damaging |
Het |
| Nprl3 |
A |
G |
11: 32,187,357 (GRCm39) |
I325T |
probably damaging |
Het |
| Nr1h3 |
T |
A |
2: 91,021,229 (GRCm39) |
Q186L |
probably benign |
Het |
| Oas1f |
A |
G |
5: 120,989,538 (GRCm39) |
E159G |
probably benign |
Het |
| Or2g7 |
A |
T |
17: 38,378,412 (GRCm39) |
M117L |
possibly damaging |
Het |
| Or4k15b |
T |
A |
14: 50,272,252 (GRCm39) |
S203C |
probably damaging |
Het |
| Or52ae7 |
T |
A |
7: 103,119,504 (GRCm39) |
F86Y |
probably damaging |
Het |
| Or52e19b |
T |
A |
7: 103,032,970 (GRCm39) |
I80F |
probably damaging |
Het |
| Or52s1b |
T |
A |
7: 102,822,242 (GRCm39) |
S201C |
probably damaging |
Het |
| Or5m12 |
A |
G |
2: 85,734,942 (GRCm39) |
F152S |
probably benign |
Het |
| Or8g4 |
T |
C |
9: 39,662,417 (GRCm39) |
I245T |
probably damaging |
Het |
| Or9a4 |
T |
A |
6: 40,549,154 (GRCm39) |
I278N |
probably benign |
Het |
| Pbxip1 |
G |
C |
3: 89,353,648 (GRCm39) |
S267T |
probably benign |
Het |
| Pcdhga10 |
A |
T |
18: 37,881,645 (GRCm39) |
I469F |
possibly damaging |
Het |
| Pkd1l1 |
A |
G |
11: 8,804,375 (GRCm39) |
S1739P |
probably damaging |
Het |
| Plcd4 |
A |
C |
1: 74,604,464 (GRCm39) |
N788T |
probably benign |
Het |
| Pms2 |
T |
A |
5: 143,867,909 (GRCm39) |
W838R |
probably damaging |
Het |
| Pnpla6 |
T |
A |
8: 3,586,562 (GRCm39) |
V926D |
probably damaging |
Het |
| Pros1 |
A |
T |
16: 62,748,516 (GRCm39) |
H663L |
possibly damaging |
Het |
| Prss55 |
T |
C |
14: 64,316,138 (GRCm39) |
|
probably null |
Het |
| Pum2 |
T |
C |
12: 8,763,904 (GRCm39) |
Y283H |
probably damaging |
Het |
| Rad21 |
A |
G |
15: 51,828,422 (GRCm39) |
S549P |
probably benign |
Het |
| Sap130 |
T |
A |
18: 31,781,182 (GRCm39) |
|
probably null |
Het |
| Sertad4 |
C |
T |
1: 192,529,189 (GRCm39) |
S209N |
probably benign |
Het |
| Slc22a28 |
C |
T |
19: 8,078,837 (GRCm39) |
R284Q |
probably damaging |
Het |
| Slco4c1 |
T |
C |
1: 96,764,650 (GRCm39) |
K474R |
probably benign |
Het |
| Stx5a |
T |
C |
19: 8,719,802 (GRCm39) |
S56P |
probably damaging |
Het |
| Svopl |
T |
C |
6: 37,991,744 (GRCm39) |
T379A |
probably damaging |
Het |
| Sypl2 |
A |
G |
3: 108,125,008 (GRCm39) |
F118L |
probably damaging |
Het |
| Tfrc |
G |
A |
16: 32,435,967 (GRCm39) |
V215M |
probably benign |
Het |
| Thnsl2 |
T |
C |
6: 71,115,652 (GRCm39) |
N185S |
probably damaging |
Het |
| Tmem104 |
T |
C |
11: 115,134,580 (GRCm39) |
I372T |
probably damaging |
Het |
| Tnfaip6 |
G |
A |
2: 51,941,070 (GRCm39) |
G204S |
probably damaging |
Het |
| Trim12a |
C |
T |
7: 103,953,335 (GRCm39) |
E259K |
probably benign |
Het |
| Tubgcp6 |
G |
A |
15: 88,986,232 (GRCm39) |
R1436C |
probably benign |
Het |
| Tyrp1 |
C |
T |
4: 80,758,864 (GRCm39) |
L246F |
probably damaging |
Het |
| Ubr4 |
G |
T |
4: 139,145,717 (GRCm39) |
V216F |
|
Het |
| Unc5a |
A |
G |
13: 55,147,319 (GRCm39) |
I409V |
possibly damaging |
Het |
| Vmn1r15 |
T |
C |
6: 57,235,399 (GRCm39) |
L89P |
probably damaging |
Het |
| Vmn1r32 |
A |
T |
6: 66,530,305 (GRCm39) |
L157* |
probably null |
Het |
| Zcchc24 |
A |
G |
14: 25,720,185 (GRCm39) |
Y160H |
probably damaging |
Het |
| Zfp184 |
A |
T |
13: 22,144,376 (GRCm39) |
H694L |
probably damaging |
Het |
| Zfp345 |
A |
C |
2: 150,314,723 (GRCm39) |
Y271* |
probably null |
Het |
| Zranb3 |
T |
C |
1: 128,030,671 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Sez6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01125:Sez6
|
APN |
11 |
77,868,115 (GRCm39) |
splice site |
probably benign |
|
|
IGL01142:Sez6
|
APN |
11 |
77,864,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02252:Sez6
|
APN |
11 |
77,865,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02332:Sez6
|
APN |
11 |
77,845,568 (GRCm39) |
splice site |
probably benign |
|
|
IGL02366:Sez6
|
APN |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02479:Sez6
|
APN |
11 |
77,868,852 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02963:Sez6
|
APN |
11 |
77,853,775 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
velum
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0089:Sez6
|
UTSW |
11 |
77,865,170 (GRCm39) |
splice site |
probably benign |
|
|
R0485:Sez6
|
UTSW |
11 |
77,844,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0598:Sez6
|
UTSW |
11 |
77,868,647 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0729:Sez6
|
UTSW |
11 |
77,867,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1117:Sez6
|
UTSW |
11 |
77,865,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1199:Sez6
|
UTSW |
11 |
77,844,711 (GRCm39) |
missense |
probably benign |
|
|
R1534:Sez6
|
UTSW |
11 |
77,853,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Sez6
|
UTSW |
11 |
77,844,329 (GRCm39) |
missense |
probably benign |
|
|
R1840:Sez6
|
UTSW |
11 |
77,844,543 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1929:Sez6
|
UTSW |
11 |
77,863,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Sez6
|
UTSW |
11 |
77,844,894 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3156:Sez6
|
UTSW |
11 |
77,844,605 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R3930:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3931:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4894:Sez6
|
UTSW |
11 |
77,866,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4904:Sez6
|
UTSW |
11 |
77,866,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5026:Sez6
|
UTSW |
11 |
77,859,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5040:Sez6
|
UTSW |
11 |
77,859,915 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5057:Sez6
|
UTSW |
11 |
77,863,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5093:Sez6
|
UTSW |
11 |
77,867,388 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5640:Sez6
|
UTSW |
11 |
77,864,585 (GRCm39) |
intron |
probably benign |
|
|
R6013:Sez6
|
UTSW |
11 |
77,864,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6126:Sez6
|
UTSW |
11 |
77,864,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6153:Sez6
|
UTSW |
11 |
77,868,648 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6279:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6300:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6475:Sez6
|
UTSW |
11 |
77,864,670 (GRCm39) |
|
|
|
|
R6722:Sez6
|
UTSW |
11 |
77,844,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6897:Sez6
|
UTSW |
11 |
77,844,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Sez6
|
UTSW |
11 |
77,844,695 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7012:Sez6
|
UTSW |
11 |
77,868,621 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7233:Sez6
|
UTSW |
11 |
77,863,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7265:Sez6
|
UTSW |
11 |
77,853,691 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7289:Sez6
|
UTSW |
11 |
77,865,149 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7405:Sez6
|
UTSW |
11 |
77,853,717 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7408:Sez6
|
UTSW |
11 |
77,844,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7485:Sez6
|
UTSW |
11 |
77,864,711 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7592:Sez6
|
UTSW |
11 |
77,868,876 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7778:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7793:Sez6
|
UTSW |
11 |
77,868,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Sez6
|
UTSW |
11 |
77,867,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8008:Sez6
|
UTSW |
11 |
77,864,082 (GRCm39) |
nonsense |
probably null |
|
|
R8840:Sez6
|
UTSW |
11 |
77,867,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8947:Sez6
|
UTSW |
11 |
77,844,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Sez6
|
UTSW |
11 |
77,865,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9040:Sez6
|
UTSW |
11 |
77,864,762 (GRCm39) |
missense |
probably benign |
|
|
R9081:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9082:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9092:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9094:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9095:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9097:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9169:Sez6
|
UTSW |
11 |
77,868,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9513:Sez6
|
UTSW |
11 |
77,865,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9632:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9646:Sez6
|
UTSW |
11 |
77,867,632 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9709:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
X0013:Sez6
|
UTSW |
11 |
77,845,606 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0067:Sez6
|
UTSW |
11 |
77,865,264 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1088:Sez6
|
UTSW |
11 |
77,864,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCTTCAAGAGGGGCTAGAAAG -3'
(R):5'- TTCGTCATCCCCTGAAGCTG -3'
Sequencing Primer
(F):5'- TTCCAGCCGGACTCACC -3'
(R):5'- TCATCCCCTGAAGCTGTGGAG -3'
|
| Posted On |
2020-09-15 |
Incidental Mutation