Mutagenetix > Incidental Mutation

Incidental Mutation 'R8425:Abca13'

653425

Institutional Source

Beutler Lab

Gene Symbol

Abca13

Ensembl Gene

ENSMUSG00000004668

Gene Name

ATP-binding cassette, sub-family A (ABC1), member 13

Synonyms

A930002G16Rik

MMRRC Submission

067819-MU

Accession Numbers

NCBI RefSeq: NM_178259.3; MGI:2388707

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8425 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

9191942-9684259 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 9314623 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Phenylalanine at position 3002 (V3002F)

Ref Sequence

ENSEMBL: ENSMUSP00000040465 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042740]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000042740
AA Change: V3002F

PolyPhen 2 Score 0.917 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000040465
Gene: ENSMUSG00000004668
AA Change: V3002F

Domain	Start	End	E-Value	Type
transmembrane domain	20	42	N/A	INTRINSIC
low complexity region	358	379	N/A	INTRINSIC
low complexity region	441	451	N/A	INTRINSIC
low complexity region	820	831	N/A	INTRINSIC
low complexity region	1382	1393	N/A	INTRINSIC
low complexity region	1721	1737	N/A	INTRINSIC
low complexity region	1859	1872	N/A	INTRINSIC
Pfam:ABC2_membrane_3	3288	3740	4.7e-21	PFAM
low complexity region	3796	3809	N/A	INTRINSIC
AAA	3835	4019	8.08e-12	SMART
transmembrane domain	4206	4228	N/A	INTRINSIC
Pfam:ABC2_membrane_3	4317	4646	1.6e-33	PFAM
AAA	4721	4909	8.86e-9	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]

Allele List at MGI

All alleles(3) : Targeted(3)

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700013D24Rik	T	C	6: 124,347,786 (GRCm38)	E92G	possibly damaging	Het
4921501E09Rik	C	A	17: 33,067,064 (GRCm38)	A255S	probably benign	Het
Aasdh	A	T	5: 76,886,277 (GRCm38)	Y476N	possibly damaging	Het
Adam23	C	T	1: 63,585,377 (GRCm38)	T788I	probably damaging	Het
Adgrb2	A	G	4: 130,005,057 (GRCm38)	T282A	possibly damaging	Het
Adgrg1	T	C	8: 95,008,407 (GRCm38)	Y402H	probably damaging	Het
Agpat2	A	T	2: 26,593,654 (GRCm38)	L257Q	probably benign	Het
Agpat3	A	T	10: 78,282,377 (GRCm38)	V255E	possibly damaging	Het
Akap6	A	G	12: 52,886,621 (GRCm38)	I299V	probably benign	Het
Anapc1	A	T	2: 128,669,868 (GRCm38)	F468L	probably damaging	Het
Apob	T	A	12: 7,988,842 (GRCm38)	N431K	possibly damaging	Het
Asprv1	T	A	6: 86,628,869 (GRCm38)	D232E	probably benign	Het
AW209491	A	G	13: 14,637,336 (GRCm38)	Y258C	probably damaging	Het
Bach2	C	T	4: 32,562,316 (GRCm38)	P261L	probably benign	Het
Cap2	T	A	13: 46,609,732 (GRCm38)	I146K	probably damaging	Het
Catsperb	A	T	12: 101,602,769 (GRCm38)	Q900L	probably benign	Het
Ccdc187	A	T	2: 26,281,536 (GRCm38)	V310D	probably damaging	Het
Cenpe	G	T	3: 135,242,627 (GRCm38)	G1275*	probably null	Het
Chd8	C	T	14: 52,210,555 (GRCm38)	G1663D	probably damaging	Het
Col6a5	T	A	9: 105,945,957 (GRCm38)	Y67F	unknown	Het
Cuzd1	G	T	7: 131,317,991 (GRCm38)	T132K	possibly damaging	Het
Ddr2	T	A	1: 170,036,016 (GRCm38)		probably benign	Het
Ddx42	T	C	11: 106,247,724 (GRCm38)	I783T	probably benign	Het
Dennd4a	T	A	9: 64,838,974 (GRCm38)	D47E	probably damaging	Het
Dirc2	A	T	16: 35,735,597 (GRCm38)	N164K	probably benign	Het
Dvl2	T	G	11: 70,007,847 (GRCm38)	W379G	probably damaging	Het
Ehbp1	A	G	11: 22,013,495 (GRCm38)	L1160P	probably damaging	Het
Eml6	A	G	11: 29,755,008 (GRCm38)	V1512A	probably benign	Het
Ephb6	T	C	6: 41,618,646 (GRCm38)	S780P	probably damaging	Het
Exo5	G	A	4: 120,922,363 (GRCm38)	L102F	probably benign	Het
Fam220a	A	T	5: 143,562,839 (GRCm38)	K2M	possibly damaging	Het
Fanci	A	T	7: 79,433,541 (GRCm38)	I731L	probably benign	Het
Gbp8	A	G	5: 105,017,774 (GRCm38)	S338P	probably damaging	Het
H2-M11	T	C	17: 36,548,757 (GRCm38)	I214T	probably benign	Het
Hhatl	C	A	9: 121,789,102 (GRCm38)	A196S	probably benign	Het
Hspg2	C	A	4: 137,550,867 (GRCm38)	C2988*	probably null	Het
Ifi213	A	G	1: 173,589,860 (GRCm38)	S329P	probably benign	Het
Lingo3	G	T	10: 80,834,982 (GRCm38)	F371L	probably benign	Het
Maml2	C	T	9: 13,620,117 (GRCm38)	T209I		Het
Ndufaf3	T	C	9: 108,566,983 (GRCm38)		probably benign	Het
Nfatc2	C	T	2: 168,536,296 (GRCm38)	G483E	probably damaging	Het
Npy6r	A	C	18: 44,276,003 (GRCm38)	T164P	probably benign	Het
Olfr117	T	A	17: 37,660,084 (GRCm38)	N83I	probably damaging	Het
Olfr1221	T	A	2: 89,112,393 (GRCm38)	N40Y	probably damaging	Het
Olfr132	T	C	17: 38,131,036 (GRCm38)	D52G	possibly damaging	Het
Olfr1502	T	C	19: 13,862,485 (GRCm38)	S231P	probably benign	Het
Olfr173	A	G	16: 58,797,603 (GRCm38)	M81T	probably benign	Het
Olfr659	A	G	7: 104,671,295 (GRCm38)	N198D	probably damaging	Het
Omg	T	C	11: 79,502,000 (GRCm38)	E344G	possibly damaging	Het
P2rx7	A	G	5: 122,670,458 (GRCm38)	E301G	probably damaging	Het
Pkhd1l1	T	C	15: 44,574,515 (GRCm38)	S3569P	probably benign	Het
Pkn3	G	A	2: 30,086,501 (GRCm38)		probably null	Het
Proc	C	T	18: 32,123,358 (GRCm38)	V419M	probably damaging	Het
Prss37	C	T	6: 40,516,118 (GRCm38)	W138*	probably null	Het
Prss52	T	A	14: 64,112,560 (GRCm38)	L212*	probably null	Het
Rnps1	A	G	17: 24,418,169 (GRCm38)	K8E	unknown	Het
Rpf2	A	T	10: 40,225,433 (GRCm38)	L202*	probably null	Het
Saraf	C	T	8: 34,165,448 (GRCm38)	P227L	probably benign	Het
Serpinb5	T	A	1: 106,881,785 (GRCm38)	M307K	possibly damaging	Het
Slc46a1	T	C	11: 78,468,645 (GRCm38)	S368P	possibly damaging	Het
Slfn8	T	A	11: 83,004,615 (GRCm38)	Q455L	possibly damaging	Het
Sv2b	A	G	7: 75,117,599 (GRCm38)	M683T	probably damaging	Het
Tacc3	G	T	5: 33,664,530 (GRCm38)	L211F	unknown	Het
Tbc1d8	A	G	1: 39,381,409 (GRCm38)	V681A	probably damaging	Het
Tbkbp1	T	C	11: 97,138,851 (GRCm38)	E493G	unknown	Het
Th	A	T	7: 142,894,086 (GRCm38)	V420E	possibly damaging	Het
Tmem132c	T	G	5: 127,564,357 (GRCm38)	V115G		Het
Usp40	G	A	1: 87,959,836 (GRCm38)	R915C	probably benign	Het
Wdr81	T	A	11: 75,451,522 (GRCm38)	H973L	possibly damaging	Het
Zdhhc6	A	G	19: 55,314,444 (GRCm38)	S42P	probably benign	Het
Zfp369	T	A	13: 65,296,675 (GRCm38)	I544N	possibly damaging	Het

Other mutations in Abca13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Abca13	APN	11	9,297,443 (GRCm38)	missense	probably benign	0.24
IGL00481:Abca13	APN	11	9,290,969 (GRCm38)	missense	probably damaging	0.99
IGL00707:Abca13	APN	11	9,291,586 (GRCm38)	missense	probably damaging	0.99
IGL00755:Abca13	APN	11	9,542,102 (GRCm38)	missense	possibly damaging	0.87
IGL00771:Abca13	APN	11	9,290,870 (GRCm38)	missense	probably damaging	1.00
IGL00802:Abca13	APN	11	9,297,717 (GRCm38)	missense	probably damaging	0.96
IGL00807:Abca13	APN	11	9,378,285 (GRCm38)	missense	probably benign	0.10
IGL00977:Abca13	APN	11	9,399,284 (GRCm38)	missense	probably damaging	1.00
IGL01064:Abca13	APN	11	9,483,855 (GRCm38)	missense	probably benign	0.01
IGL01100:Abca13	APN	11	9,274,673 (GRCm38)	splice site	probably null
IGL01290:Abca13	APN	11	9,256,232 (GRCm38)	missense	probably damaging	1.00
IGL01299:Abca13	APN	11	9,298,743 (GRCm38)	missense	probably benign	0.22
IGL01302:Abca13	APN	11	9,399,470 (GRCm38)	splice site	probably benign
IGL01307:Abca13	APN	11	9,297,159 (GRCm38)	missense	possibly damaging	0.86
IGL01349:Abca13	APN	11	9,292,076 (GRCm38)	missense	probably benign	0.05
IGL01351:Abca13	APN	11	9,267,565 (GRCm38)	missense	probably benign	0.28
IGL01446:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01453:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01461:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01476:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01506:Abca13	APN	11	9,297,447 (GRCm38)	missense	probably benign	0.36
IGL01527:Abca13	APN	11	9,290,788 (GRCm38)	missense	possibly damaging	0.49
IGL01559:Abca13	APN	11	9,309,020 (GRCm38)	missense	possibly damaging	0.82
IGL01580:Abca13	APN	11	9,293,527 (GRCm38)	missense	probably benign	0.00
IGL01679:Abca13	APN	11	9,298,071 (GRCm38)	missense	probably benign	0.07
IGL01731:Abca13	APN	11	9,249,749 (GRCm38)	splice site	probably benign
IGL01762:Abca13	APN	11	9,315,423 (GRCm38)	missense	probably benign	0.18
IGL01781:Abca13	APN	11	9,399,280 (GRCm38)	missense	probably damaging	1.00
IGL01802:Abca13	APN	11	9,292,438 (GRCm38)	missense	probably benign	0.00
IGL01809:Abca13	APN	11	9,290,339 (GRCm38)	missense	probably damaging	0.96
IGL01906:Abca13	APN	11	9,216,225 (GRCm38)	missense	probably damaging	1.00
IGL01928:Abca13	APN	11	9,683,342 (GRCm38)	missense	probably benign	0.13
IGL01940:Abca13	APN	11	9,567,661 (GRCm38)	splice site	probably benign
IGL01993:Abca13	APN	11	9,258,452 (GRCm38)	unclassified	probably benign
IGL02039:Abca13	APN	11	9,297,193 (GRCm38)	nonsense	probably null
IGL02159:Abca13	APN	11	9,314,545 (GRCm38)	missense	probably benign	0.00
IGL02202:Abca13	APN	11	9,288,529 (GRCm38)	missense	possibly damaging	0.55
IGL02268:Abca13	APN	11	9,290,626 (GRCm38)	missense	probably benign	0.00
IGL02332:Abca13	APN	11	9,291,482 (GRCm38)	missense	probably damaging	0.98
IGL02380:Abca13	APN	11	9,291,599 (GRCm38)	missense	possibly damaging	0.73
IGL02466:Abca13	APN	11	9,297,527 (GRCm38)	missense	probably benign	0.00
IGL02505:Abca13	APN	11	9,581,498 (GRCm38)	missense	probably damaging	1.00
IGL02507:Abca13	APN	11	9,399,388 (GRCm38)	missense	probably damaging	1.00
IGL02558:Abca13	APN	11	9,399,387 (GRCm38)	missense	probably damaging	1.00
IGL02581:Abca13	APN	11	9,399,132 (GRCm38)	splice site	probably benign
IGL02586:Abca13	APN	11	9,293,983 (GRCm38)	missense	possibly damaging	0.56
IGL02598:Abca13	APN	11	9,431,898 (GRCm38)	missense	probably damaging	1.00
IGL02747:Abca13	APN	11	9,373,282 (GRCm38)	nonsense	probably null
IGL02893:Abca13	APN	11	9,290,543 (GRCm38)	missense	probably damaging	0.96
IGL02930:Abca13	APN	11	9,378,226 (GRCm38)	missense	possibly damaging	0.86
IGL02967:Abca13	APN	11	9,378,291 (GRCm38)	missense	probably damaging	0.99
IGL02983:Abca13	APN	11	9,290,663 (GRCm38)	missense	probably benign	0.40
IGL02999:Abca13	APN	11	9,581,757 (GRCm38)	splice site	probably benign
IGL03100:Abca13	APN	11	9,258,527 (GRCm38)	missense	probably benign	0.25
IGL03114:Abca13	APN	11	9,528,999 (GRCm38)	missense	probably benign	0.06
IGL03230:Abca13	APN	11	9,294,313 (GRCm38)	missense	probably benign	0.02
IGL03329:Abca13	APN	11	9,298,047 (GRCm38)	missense	probably benign	0.08
IGL03380:Abca13	APN	11	9,298,574 (GRCm38)	missense	probably benign	0.10
IGL02835:Abca13	UTSW	11	9,451,515 (GRCm38)	missense	probably damaging	1.00
PIT4366001:Abca13	UTSW	11	9,294,962 (GRCm38)	missense	probably benign
PIT4458001:Abca13	UTSW	11	9,298,304 (GRCm38)	missense	probably benign	0.05
R0017:Abca13	UTSW	11	9,292,775 (GRCm38)	missense	probably damaging	0.99
R0079:Abca13	UTSW	11	9,293,493 (GRCm38)	missense	probably benign	0.00
R0089:Abca13	UTSW	11	9,292,886 (GRCm38)	missense	possibly damaging	0.76
R0103:Abca13	UTSW	11	9,273,951 (GRCm38)	missense	probably damaging	1.00
R0103:Abca13	UTSW	11	9,273,951 (GRCm38)	missense	probably damaging	1.00
R0113:Abca13	UTSW	11	9,292,114 (GRCm38)	missense	possibly damaging	0.54
R0119:Abca13	UTSW	11	9,298,076 (GRCm38)	missense	probably benign	0.03
R0152:Abca13	UTSW	11	9,581,724 (GRCm38)	missense	probably damaging	0.98
R0255:Abca13	UTSW	11	9,581,545 (GRCm38)	missense	probably damaging	1.00
R0277:Abca13	UTSW	11	9,294,701 (GRCm38)	missense	probably benign	0.25
R0278:Abca13	UTSW	11	9,378,215 (GRCm38)	missense	probably damaging	1.00
R0294:Abca13	UTSW	11	9,269,122 (GRCm38)	splice site	probably null
R0299:Abca13	UTSW	11	9,298,076 (GRCm38)	missense	probably benign	0.03
R0310:Abca13	UTSW	11	9,293,810 (GRCm38)	missense	probably benign	0.36
R0317:Abca13	UTSW	11	9,293,459 (GRCm38)	missense	probably damaging	1.00
R0323:Abca13	UTSW	11	9,294,701 (GRCm38)	missense	probably benign	0.25
R0324:Abca13	UTSW	11	9,297,669 (GRCm38)	missense	possibly damaging	0.76
R0329:Abca13	UTSW	11	9,399,430 (GRCm38)	missense	probably damaging	0.97
R0336:Abca13	UTSW	11	9,298,481 (GRCm38)	missense	probably benign	0.04
R0346:Abca13	UTSW	11	9,566,278 (GRCm38)	missense	probably damaging	0.99
R0380:Abca13	UTSW	11	9,588,500 (GRCm38)	splice site	probably null
R0382:Abca13	UTSW	11	9,636,650 (GRCm38)	splice site	probably benign
R0482:Abca13	UTSW	11	9,328,207 (GRCm38)	missense	possibly damaging	0.88
R0487:Abca13	UTSW	11	9,331,687 (GRCm38)	missense	probably benign	0.07
R0491:Abca13	UTSW	11	9,298,235 (GRCm38)	missense	probably benign	0.02
R0496:Abca13	UTSW	11	9,291,701 (GRCm38)	missense	probably benign	0.01
R0505:Abca13	UTSW	11	9,291,058 (GRCm38)	missense	probably benign	0.00
R0511:Abca13	UTSW	11	9,294,559 (GRCm38)	missense	probably benign
R0525:Abca13	UTSW	11	9,293,371 (GRCm38)	missense	probably damaging	1.00
R0538:Abca13	UTSW	11	9,267,622 (GRCm38)	critical splice donor site	probably null
R0615:Abca13	UTSW	11	9,256,197 (GRCm38)	missense	probably damaging	0.96
R0634:Abca13	UTSW	11	9,314,491 (GRCm38)	missense	possibly damaging	0.59
R0699:Abca13	UTSW	11	9,588,508 (GRCm38)	splice site	probably benign
R0848:Abca13	UTSW	11	9,682,011 (GRCm38)	nonsense	probably null
R0883:Abca13	UTSW	11	9,291,238 (GRCm38)	nonsense	probably null
R0892:Abca13	UTSW	11	9,298,305 (GRCm38)	missense	probably benign	0.00
R0904:Abca13	UTSW	11	9,298,740 (GRCm38)	missense	probably benign	0.22
R0968:Abca13	UTSW	11	9,298,016 (GRCm38)	missense	probably benign	0.00
R1187:Abca13	UTSW	11	9,528,981 (GRCm38)	missense	probably benign	0.00
R1299:Abca13	UTSW	11	9,294,821 (GRCm38)	missense	possibly damaging	0.94
R1323:Abca13	UTSW	11	9,290,937 (GRCm38)	missense	possibly damaging	0.86
R1323:Abca13	UTSW	11	9,290,937 (GRCm38)	missense	possibly damaging	0.86
R1368:Abca13	UTSW	11	9,291,836 (GRCm38)	missense	probably benign
R1387:Abca13	UTSW	11	9,682,085 (GRCm38)	nonsense	probably null
R1436:Abca13	UTSW	11	9,292,646 (GRCm38)	missense	probably damaging	0.99
R1449:Abca13	UTSW	11	9,298,580 (GRCm38)	missense	probably damaging	1.00
R1450:Abca13	UTSW	11	9,430,531 (GRCm38)	splice site	probably benign
R1462:Abca13	UTSW	11	9,483,924 (GRCm38)	splice site	probably benign
R1465:Abca13	UTSW	11	9,399,303 (GRCm38)	missense	probably damaging	1.00
R1465:Abca13	UTSW	11	9,399,303 (GRCm38)	missense	probably damaging	1.00
R1466:Abca13	UTSW	11	9,570,536 (GRCm38)	splice site	probably benign
R1494:Abca13	UTSW	11	9,466,429 (GRCm38)	nonsense	probably null
R1559:Abca13	UTSW	11	9,399,180 (GRCm38)	missense	probably null	1.00
R1564:Abca13	UTSW	11	9,434,316 (GRCm38)	nonsense	probably null
R1698:Abca13	UTSW	11	9,314,507 (GRCm38)	missense	probably benign	0.13
R1728:Abca13	UTSW	11	9,249,680 (GRCm38)	missense	probably benign	0.02
R1734:Abca13	UTSW	11	9,585,460 (GRCm38)	missense	probably benign	0.03
R1781:Abca13	UTSW	11	9,269,194 (GRCm38)	missense	probably damaging	1.00
R1782:Abca13	UTSW	11	9,297,971 (GRCm38)	missense	probably benign	0.36
R1807:Abca13	UTSW	11	9,291,755 (GRCm38)	missense	probably damaging	0.98
R1830:Abca13	UTSW	11	9,290,350 (GRCm38)	missense	probably benign	0.04
R1869:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1870:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1871:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1903:Abca13	UTSW	11	9,466,411 (GRCm38)	missense	probably benign	0.13
R1916:Abca13	UTSW	11	9,534,456 (GRCm38)	missense	probably damaging	1.00
R1936:Abca13	UTSW	11	9,293,595 (GRCm38)	missense	probably benign	0.13
R1976:Abca13	UTSW	11	9,397,815 (GRCm38)	missense	probably damaging	1.00
R2001:Abca13	UTSW	11	9,273,967 (GRCm38)	missense	probably benign	0.01
R2007:Abca13	UTSW	11	9,191,987 (GRCm38)	missense	probably benign	0.19
R2016:Abca13	UTSW	11	9,290,619 (GRCm38)	missense	probably damaging	1.00
R2017:Abca13	UTSW	11	9,290,619 (GRCm38)	missense	probably damaging	1.00
R2034:Abca13	UTSW	11	9,292,628 (GRCm38)	missense	possibly damaging	0.83
R2051:Abca13	UTSW	11	9,328,098 (GRCm38)	missense	probably benign	0.04
R2075:Abca13	UTSW	11	9,522,382 (GRCm38)	missense	probably damaging	1.00
R2118:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2120:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2124:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2148:Abca13	UTSW	11	9,615,764 (GRCm38)	missense	probably damaging	1.00
R2149:Abca13	UTSW	11	9,267,508 (GRCm38)	missense	possibly damaging	0.68
R2157:Abca13	UTSW	11	9,577,170 (GRCm38)	missense	probably damaging	0.97
R2167:Abca13	UTSW	11	9,288,532 (GRCm38)	missense	probably benign	0.19
R2261:Abca13	UTSW	11	9,292,288 (GRCm38)	missense	probably benign
R2263:Abca13	UTSW	11	9,274,702 (GRCm38)	missense	probably benign	0.04
R2281:Abca13	UTSW	11	9,328,136 (GRCm38)	missense	probably damaging	0.98
R2340:Abca13	UTSW	11	9,399,165 (GRCm38)	missense	probably damaging	0.99
R2357:Abca13	UTSW	11	9,297,336 (GRCm38)	missense	probably damaging	1.00
R2370:Abca13	UTSW	11	9,256,185 (GRCm38)	missense	possibly damaging	0.85
R2384:Abca13	UTSW	11	9,267,450 (GRCm38)	splice site	probably benign
R2393:Abca13	UTSW	11	9,275,057 (GRCm38)	nonsense	probably null
R2432:Abca13	UTSW	11	9,451,333 (GRCm38)	splice site	probably benign
R2446:Abca13	UTSW	11	9,275,101 (GRCm38)	missense	probably benign
R2568:Abca13	UTSW	11	9,333,310 (GRCm38)	missense	probably benign	0.40
R2847:Abca13	UTSW	11	9,294,584 (GRCm38)	missense	possibly damaging	0.59
R2860:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2861:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2862:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2877:Abca13	UTSW	11	9,291,889 (GRCm38)	missense	possibly damaging	0.91
R2878:Abca13	UTSW	11	9,291,889 (GRCm38)	missense	possibly damaging	0.91
R3748:Abca13	UTSW	11	9,316,119 (GRCm38)	splice site	probably benign
R3789:Abca13	UTSW	11	9,510,668 (GRCm38)	missense	probably damaging	0.97
R3933:Abca13	UTSW	11	9,354,856 (GRCm38)	missense	probably damaging	1.00
R3981:Abca13	UTSW	11	9,532,407 (GRCm38)	missense	probably benign
R4002:Abca13	UTSW	11	9,585,415 (GRCm38)	missense	probably benign	0.00
R4010:Abca13	UTSW	11	9,622,013 (GRCm38)	splice site	probably benign
R4011:Abca13	UTSW	11	9,622,013 (GRCm38)	splice site	probably benign
R4127:Abca13	UTSW	11	9,191,973 (GRCm38)	missense	probably benign	0.00
R4214:Abca13	UTSW	11	9,293,877 (GRCm38)	missense	probably damaging	0.96
R4236:Abca13	UTSW	11	9,256,205 (GRCm38)	missense	probably damaging	1.00
R4237:Abca13	UTSW	11	9,434,188 (GRCm38)	missense	probably benign	0.01
R4359:Abca13	UTSW	11	9,297,629 (GRCm38)	missense	probably benign	0.02
R4378:Abca13	UTSW	11	9,293,644 (GRCm38)	missense	probably benign	0.00
R4389:Abca13	UTSW	11	9,297,878 (GRCm38)	missense	probably damaging	0.98
R4392:Abca13	UTSW	11	9,309,034 (GRCm38)	missense	possibly damaging	0.94
R4623:Abca13	UTSW	11	9,309,130 (GRCm38)	missense	probably damaging	1.00
R4684:Abca13	UTSW	11	9,434,193 (GRCm38)	nonsense	probably null
R4691:Abca13	UTSW	11	9,434,195 (GRCm38)	missense	probably damaging	1.00
R4700:Abca13	UTSW	11	9,292,306 (GRCm38)	missense	possibly damaging	0.59
R4701:Abca13	UTSW	11	9,292,306 (GRCm38)	missense	possibly damaging	0.59
R4704:Abca13	UTSW	11	9,276,990 (GRCm38)	missense	possibly damaging	0.94
R4751:Abca13	UTSW	11	9,277,973 (GRCm38)	critical splice donor site	probably null
R4772:Abca13	UTSW	11	9,315,339 (GRCm38)	splice site	probably null
R4782:Abca13	UTSW	11	9,328,096 (GRCm38)	missense	probably damaging	0.96
R4801:Abca13	UTSW	11	9,522,341 (GRCm38)	missense	possibly damaging	0.94
R4802:Abca13	UTSW	11	9,522,341 (GRCm38)	missense	possibly damaging	0.94
R4819:Abca13	UTSW	11	9,290,421 (GRCm38)	missense	possibly damaging	0.88
R4831:Abca13	UTSW	11	9,542,077 (GRCm38)	nonsense	probably null
R4851:Abca13	UTSW	11	9,483,890 (GRCm38)	missense	probably benign	0.02
R4857:Abca13	UTSW	11	9,294,143 (GRCm38)	missense	probably benign	0.22
R4869:Abca13	UTSW	11	9,315,434 (GRCm38)	splice site	probably null
R4982:Abca13	UTSW	11	9,292,348 (GRCm38)	missense	possibly damaging	0.58
R5031:Abca13	UTSW	11	9,297,678 (GRCm38)	missense	probably damaging	0.99
R5044:Abca13	UTSW	11	9,373,323 (GRCm38)	missense	possibly damaging	0.80
R5092:Abca13	UTSW	11	9,258,535 (GRCm38)	missense	probably damaging	1.00
R5155:Abca13	UTSW	11	9,532,447 (GRCm38)	missense	probably damaging	0.98
R5173:Abca13	UTSW	11	9,682,032 (GRCm38)	frame shift	probably null
R5180:Abca13	UTSW	11	9,466,510 (GRCm38)	missense	probably benign	0.01
R5244:Abca13	UTSW	11	9,275,081 (GRCm38)	missense	probably benign	0.28
R5257:Abca13	UTSW	11	9,249,684 (GRCm38)	missense	possibly damaging	0.94
R5258:Abca13	UTSW	11	9,249,684 (GRCm38)	missense	possibly damaging	0.94
R5299:Abca13	UTSW	11	9,431,861 (GRCm38)	missense	probably damaging	1.00
R5363:Abca13	UTSW	11	9,277,035 (GRCm38)	missense	possibly damaging	0.75
R5365:Abca13	UTSW	11	9,628,629 (GRCm38)	missense	probably damaging	1.00
R5419:Abca13	UTSW	11	9,193,533 (GRCm38)	critical splice donor site	probably null
R5426:Abca13	UTSW	11	9,290,722 (GRCm38)	missense	probably damaging	1.00
R5468:Abca13	UTSW	11	9,294,062 (GRCm38)	missense	probably damaging	1.00
R5477:Abca13	UTSW	11	9,301,298 (GRCm38)	missense	possibly damaging	0.49
R5541:Abca13	UTSW	11	9,291,545 (GRCm38)	missense	probably benign	0.00
R5553:Abca13	UTSW	11	9,328,158 (GRCm38)	missense	probably damaging	1.00
R5556:Abca13	UTSW	11	9,258,546 (GRCm38)	missense	possibly damaging	0.91
R5566:Abca13	UTSW	11	9,294,615 (GRCm38)	nonsense	probably null
R5582:Abca13	UTSW	11	9,636,639 (GRCm38)	splice site	probably null
R5604:Abca13	UTSW	11	9,566,279 (GRCm38)	missense	probably damaging	0.97
R5609:Abca13	UTSW	11	9,403,874 (GRCm38)	missense	probably benign	0.01
R5617:Abca13	UTSW	11	9,277,891 (GRCm38)	missense	probably benign	0.00
R5693:Abca13	UTSW	11	9,316,233 (GRCm38)	missense	probably benign	0.29
R5707:Abca13	UTSW	11	9,510,620 (GRCm38)	missense	probably damaging	1.00
R5725:Abca13	UTSW	11	9,577,181 (GRCm38)	missense	probably benign	0.00
R5728:Abca13	UTSW	11	9,570,576 (GRCm38)	missense	probably damaging	1.00
R5738:Abca13	UTSW	11	9,621,917 (GRCm38)	missense	probably damaging	1.00
R5758:Abca13	UTSW	11	9,314,536 (GRCm38)	missense	probably damaging	0.97
R5762:Abca13	UTSW	11	9,581,665 (GRCm38)	missense	probably damaging	1.00
R5771:Abca13	UTSW	11	9,291,411 (GRCm38)	missense	probably damaging	1.00
R5809:Abca13	UTSW	11	9,293,692 (GRCm38)	missense	probably damaging	1.00
R5826:Abca13	UTSW	11	9,682,056 (GRCm38)	missense	probably damaging	0.99
R5831:Abca13	UTSW	11	9,567,777 (GRCm38)	nonsense	probably null
R5834:Abca13	UTSW	11	9,277,974 (GRCm38)	critical splice donor site	probably null
R5902:Abca13	UTSW	11	9,297,177 (GRCm38)	missense	probably damaging	1.00
R5933:Abca13	UTSW	11	9,249,658 (GRCm38)	missense	possibly damaging	0.63
R5945:Abca13	UTSW	11	9,293,398 (GRCm38)	missense	probably benign	0.04
R5969:Abca13	UTSW	11	9,292,214 (GRCm38)	nonsense	probably null
R5985:Abca13	UTSW	11	9,291,628 (GRCm38)	missense	probably benign	0.02
R5998:Abca13	UTSW	11	9,567,708 (GRCm38)	missense	probably damaging	0.97
R6021:Abca13	UTSW	11	9,290,465 (GRCm38)	nonsense	probably null
R6022:Abca13	UTSW	11	9,290,759 (GRCm38)	missense	probably damaging	1.00
R6032:Abca13	UTSW	11	9,297,752 (GRCm38)	missense	possibly damaging	0.52
R6032:Abca13	UTSW	11	9,297,752 (GRCm38)	missense	possibly damaging	0.52
R6105:Abca13	UTSW	11	9,397,812 (GRCm38)	missense	probably damaging	1.00
R6153:Abca13	UTSW	11	9,301,259 (GRCm38)	critical splice acceptor site	probably null
R6162:Abca13	UTSW	11	9,309,047 (GRCm38)	missense	probably damaging	1.00
R6187:Abca13	UTSW	11	9,309,085 (GRCm38)	missense	probably damaging	1.00
R6247:Abca13	UTSW	11	9,403,874 (GRCm38)	missense	probably benign	0.01
R6329:Abca13	UTSW	11	9,277,937 (GRCm38)	missense	probably damaging	1.00
R6352:Abca13	UTSW	11	9,309,139 (GRCm38)	splice site	probably null
R6367:Abca13	UTSW	11	9,216,248 (GRCm38)	missense	possibly damaging	0.85
R6423:Abca13	UTSW	11	9,298,778 (GRCm38)	missense	probably benign	0.01
R6424:Abca13	UTSW	11	9,510,542 (GRCm38)	missense	probably benign
R6456:Abca13	UTSW	11	9,290,474 (GRCm38)	missense	possibly damaging	0.94
R6490:Abca13	UTSW	11	9,298,661 (GRCm38)	missense	probably benign	0.00
R6547:Abca13	UTSW	11	9,274,757 (GRCm38)	missense	probably benign	0.04
R6594:Abca13	UTSW	11	9,294,632 (GRCm38)	missense	possibly damaging	0.52
R6604:Abca13	UTSW	11	9,378,384 (GRCm38)	missense	probably damaging	1.00
R6614:Abca13	UTSW	11	9,294,371 (GRCm38)	missense	probably benign	0.04
R6736:Abca13	UTSW	11	9,465,058 (GRCm38)	missense	probably damaging	1.00
R6742:Abca13	UTSW	11	9,328,168 (GRCm38)	missense	probably damaging	1.00
R6791:Abca13	UTSW	11	9,378,504 (GRCm38)	missense	probably damaging	1.00
R6834:Abca13	UTSW	11	9,275,110 (GRCm38)	missense	possibly damaging	0.48
R6936:Abca13	UTSW	11	9,298,568 (GRCm38)	missense	probably damaging	0.96
R6955:Abca13	UTSW	11	9,294,307 (GRCm38)	missense	probably benign	0.28
R7031:Abca13	UTSW	11	9,621,892 (GRCm38)	missense	probably damaging	1.00
R7065:Abca13	UTSW	11	9,292,595 (GRCm38)	missense	probably benign	0.02
R7067:Abca13	UTSW	11	9,291,845 (GRCm38)	missense	probably benign	0.14
R7070:Abca13	UTSW	11	9,290,701 (GRCm38)	missense	probably benign	0.06
R7094:Abca13	UTSW	11	9,298,610 (GRCm38)	missense	probably damaging	0.96
R7102:Abca13	UTSW	11	9,335,215 (GRCm38)	missense	probably damaging	1.00
R7105:Abca13	UTSW	11	9,397,842 (GRCm38)	missense	probably damaging	1.00
R7131:Abca13	UTSW	11	9,291,893 (GRCm38)	missense	probably benign	0.37
R7155:Abca13	UTSW	11	9,529,010 (GRCm38)	missense	probably benign
R7158:Abca13	UTSW	11	9,273,982 (GRCm38)	missense	probably benign
R7212:Abca13	UTSW	11	9,298,854 (GRCm38)	missense	probably benign	0.04
R7215:Abca13	UTSW	11	9,288,405 (GRCm38)	splice site	probably null
R7228:Abca13	UTSW	11	9,297,653 (GRCm38)	missense	probably benign
R7231:Abca13	UTSW	11	9,294,175 (GRCm38)	missense	probably benign	0.25
R7247:Abca13	UTSW	11	9,290,732 (GRCm38)	missense	probably benign	0.00
R7278:Abca13	UTSW	11	9,291,126 (GRCm38)	missense	possibly damaging	0.56
R7299:Abca13	UTSW	11	9,294,649 (GRCm38)	missense	probably damaging	0.98
R7304:Abca13	UTSW	11	9,297,203 (GRCm38)	missense	probably benign
R7328:Abca13	UTSW	11	9,291,545 (GRCm38)	missense	probably benign	0.14
R7374:Abca13	UTSW	11	9,292,136 (GRCm38)	missense	possibly damaging	0.46
R7376:Abca13	UTSW	11	9,291,118 (GRCm38)	missense	probably benign	0.00
R7384:Abca13	UTSW	11	9,333,257 (GRCm38)	missense	probably damaging	1.00
R7395:Abca13	UTSW	11	9,291,658 (GRCm38)	missense	probably benign	0.01
R7419:Abca13	UTSW	11	9,297,833 (GRCm38)	missense	probably damaging	1.00
R7419:Abca13	UTSW	11	9,276,959 (GRCm38)	missense	probably damaging	1.00
R7421:Abca13	UTSW	11	9,510,463 (GRCm38)	missense	probably benign
R7458:Abca13	UTSW	11	9,290,777 (GRCm38)	missense	possibly damaging	0.94
R7474:Abca13	UTSW	11	9,328,088 (GRCm38)	nonsense	probably null
R7492:Abca13	UTSW	11	9,293,167 (GRCm38)	missense	probably benign	0.08
R7660:Abca13	UTSW	11	9,290,678 (GRCm38)	missense	probably benign	0.00
R7677:Abca13	UTSW	11	9,298,349 (GRCm38)	nonsense	probably null
R7744:Abca13	UTSW	11	9,290,421 (GRCm38)	missense	possibly damaging	0.88
R7790:Abca13	UTSW	11	9,297,915 (GRCm38)	missense	probably damaging	1.00
R7798:Abca13	UTSW	11	9,291,664 (GRCm38)	missense	probably benign	0.04
R7811:Abca13	UTSW	11	9,577,141 (GRCm38)	splice site	probably null
R7831:Abca13	UTSW	11	9,297,404 (GRCm38)	missense	possibly damaging	0.46
R7867:Abca13	UTSW	11	9,262,139 (GRCm38)	critical splice donor site	probably null
R7910:Abca13	UTSW	11	9,581,590 (GRCm38)	missense	probably damaging	1.00
R7964:Abca13	UTSW	11	9,316,146 (GRCm38)	missense	probably benign	0.06
R8037:Abca13	UTSW	11	9,293,904 (GRCm38)	missense	probably damaging	1.00
R8049:Abca13	UTSW	11	9,291,867 (GRCm38)	missense	probably damaging	0.99
R8059:Abca13	UTSW	11	9,373,279 (GRCm38)	missense	probably benign	0.00
R8072:Abca13	UTSW	11	9,294,574 (GRCm38)	missense	probably benign	0.10
R8078:Abca13	UTSW	11	9,301,279 (GRCm38)	missense	probably benign	0.32
R8112:Abca13	UTSW	11	9,314,624 (GRCm38)	missense	probably benign	0.01
R8146:Abca13	UTSW	11	9,397,829 (GRCm38)	missense	probably damaging	1.00
R8164:Abca13	UTSW	11	9,615,799 (GRCm38)	missense	probably damaging	1.00
R8195:Abca13	UTSW	11	9,274,735 (GRCm38)	missense	probably benign	0.00
R8220:Abca13	UTSW	11	9,434,299 (GRCm38)	missense	possibly damaging	0.58
R8235:Abca13	UTSW	11	9,262,077 (GRCm38)	missense	probably damaging	0.99
R8307:Abca13	UTSW	11	9,277,922 (GRCm38)	nonsense	probably null
R8310:Abca13	UTSW	11	9,378,269 (GRCm38)	missense	possibly damaging	0.90
R8315:Abca13	UTSW	11	9,585,502 (GRCm38)	missense	probably benign	0.44
R8315:Abca13	UTSW	11	9,378,460 (GRCm38)	missense	probably null	1.00
R8324:Abca13	UTSW	11	9,290,395 (GRCm38)	missense	probably damaging	1.00
R8375:Abca13	UTSW	11	9,397,841 (GRCm38)	missense	probably damaging	1.00
R8375:Abca13	UTSW	11	9,315,416 (GRCm38)	missense	probably benign	0.00
R8400:Abca13	UTSW	11	9,298,218 (GRCm38)	missense	probably damaging	0.97
R8400:Abca13	UTSW	11	9,293,925 (GRCm38)	missense	probably benign	0.00
R8486:Abca13	UTSW	11	9,275,092 (GRCm38)	missense	probably benign	0.00
R8493:Abca13	UTSW	11	9,510,668 (GRCm38)	missense	probably damaging	0.97
R8502:Abca13	UTSW	11	9,269,282 (GRCm38)	missense	probably benign	0.02
R8716:Abca13	UTSW	11	9,293,774 (GRCm38)	missense	probably benign	0.09
R8787:Abca13	UTSW	11	9,275,053 (GRCm38)	missense	possibly damaging	0.92
R8829:Abca13	UTSW	11	9,621,881 (GRCm38)	missense	probably damaging	1.00
R8859:Abca13	UTSW	11	9,378,397 (GRCm38)	missense
R8871:Abca13	UTSW	11	9,298,071 (GRCm38)	missense	probably benign	0.07
R8883:Abca13	UTSW	11	9,333,168 (GRCm38)	missense	probably benign	0.00
R8919:Abca13	UTSW	11	9,291,653 (GRCm38)	missense	possibly damaging	0.84
R8966:Abca13	UTSW	11	9,628,588 (GRCm38)	missense	probably damaging	1.00
R8967:Abca13	UTSW	11	9,292,696 (GRCm38)	missense	probably benign	0.18
R8969:Abca13	UTSW	11	9,277,944 (GRCm38)	missense	probably benign
R8972:Abca13	UTSW	11	9,328,138 (GRCm38)	missense	probably damaging	1.00
R9002:Abca13	UTSW	11	9,291,926 (GRCm38)	missense	possibly damaging	0.94
R9046:Abca13	UTSW	11	9,293,525 (GRCm38)	missense	probably benign	0.04
R9051:Abca13	UTSW	11	9,335,232 (GRCm38)	missense	probably damaging	1.00
R9056:Abca13	UTSW	11	9,464,921 (GRCm38)	missense	probably damaging	1.00
R9061:Abca13	UTSW	11	9,277,847 (GRCm38)	missense	probably benign	0.02
R9072:Abca13	UTSW	11	9,290,834 (GRCm38)	missense	possibly damaging	0.93
R9090:Abca13	UTSW	11	9,291,698 (GRCm38)	missense	probably damaging	0.98
R9127:Abca13	UTSW	11	9,292,080 (GRCm38)	missense	probably benign	0.03
R9164:Abca13	UTSW	11	9,328,157 (GRCm38)	missense	probably damaging	1.00
R9175:Abca13	UTSW	11	9,581,593 (GRCm38)	missense	probably damaging	0.98
R9190:Abca13	UTSW	11	9,291,886 (GRCm38)	missense	probably damaging	0.96
R9244:Abca13	UTSW	11	9,291,577 (GRCm38)	missense	probably benign	0.01
R9255:Abca13	UTSW	11	9,328,213 (GRCm38)	missense	probably damaging	1.00
R9271:Abca13	UTSW	11	9,291,698 (GRCm38)	missense	probably damaging	0.98
R9321:Abca13	UTSW	11	9,510,475 (GRCm38)	missense	probably benign	0.00
R9356:Abca13	UTSW	11	9,256,305 (GRCm38)	missense	probably benign	0.11
R9369:Abca13	UTSW	11	9,378,444 (GRCm38)	missense	probably damaging	1.00
R9423:Abca13	UTSW	11	9,290,395 (GRCm38)	missense	probably damaging	1.00
R9432:Abca13	UTSW	11	9,294,559 (GRCm38)	missense	probably benign	0.00
R9455:Abca13	UTSW	11	9,403,897 (GRCm38)	missense	probably damaging	1.00
R9486:Abca13	UTSW	11	9,290,621 (GRCm38)	missense	possibly damaging	0.88
R9492:Abca13	UTSW	11	9,293,667 (GRCm38)	nonsense	probably null
R9511:Abca13	UTSW	11	9,328,130 (GRCm38)	missense	probably benign	0.16
R9545:Abca13	UTSW	11	9,466,538 (GRCm38)	missense	probably damaging	1.00
R9566:Abca13	UTSW	11	9,464,927 (GRCm38)	missense	probably damaging	1.00
R9609:Abca13	UTSW	11	9,258,549 (GRCm38)	missense	probably damaging	1.00
R9616:Abca13	UTSW	11	9,290,501 (GRCm38)	missense	probably benign	0.00
R9651:Abca13	UTSW	11	9,585,484 (GRCm38)	missense	probably benign
R9651:Abca13	UTSW	11	9,293,741 (GRCm38)	missense	probably benign	0.31
R9653:Abca13	UTSW	11	9,293,741 (GRCm38)	missense	probably benign	0.31
R9657:Abca13	UTSW	11	9,293,379 (GRCm38)	missense	probably benign	0.35
R9684:Abca13	UTSW	11	9,333,307 (GRCm38)	missense	probably damaging	1.00
X0013:Abca13	UTSW	11	9,273,899 (GRCm38)	missense	probably benign	0.02
X0057:Abca13	UTSW	11	9,294,744 (GRCm38)	missense	probably damaging	0.96
X0066:Abca13	UTSW	11	9,267,565 (GRCm38)	missense	probably damaging	0.96
Z1088:Abca13	UTSW	11	9,294,687 (GRCm38)	missense	probably damaging	0.99
Z1176:Abca13	UTSW	11	9,267,461 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,251,376 (GRCm38)	missense	possibly damaging	0.88
Z1176:Abca13	UTSW	11	9,335,182 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,335,181 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,294,342 (GRCm38)	missense	probably benign	0.01
Z1177:Abca13	UTSW	11	9,314,545 (GRCm38)	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- GCTCGACACTTGCGGAAATAAC -3'
(R):5'- ATGGAAAGCCCTGGTGTTTG -3'

Sequencing Primer
(F):5'- AAGGTCTGCATTTACCCGTGAAC -3'
(R):5'- AAAGCCCTGGTGTTTGACTAG -3'

Posted On

2020-10-20