Incidental Mutation 'R8443:Pcnx3'
| ID |
654347 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx3
|
| Ensembl Gene |
ENSMUSG00000054874 |
| Gene Name |
pecanex homolog 3 |
| Synonyms |
Pcnxl3 |
| MMRRC Submission |
067825-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8443 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
19 |
| Chromosomal Location |
5714663-5738936 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 5736670 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 156
(S156P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109245
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000004156]
[ENSMUST00000068169]
[ENSMUST00000113615]
[ENSMUST00000141577]
|
| AlphaFold |
Q8VI59 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000004156
|
| SMART Domains |
Protein: ENSMUSP00000004156
Gene: ENSMUSG00000004054
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
36 |
N/A |
INTRINSIC |
|
SH3
|
45 |
105 |
6.79e-19 |
SMART |
|
TyrKc
|
118 |
377 |
6.83e-81 |
SMART |
|
coiled coil region
|
398 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
467 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
593 |
610 |
N/A |
INTRINSIC |
|
low complexity region
|
614 |
632 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
778 |
N/A |
INTRINSIC |
|
low complexity region
|
786 |
805 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000068169
AA Change: S156P
PolyPhen 2
Score 0.764 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000063786
Gene: ENSMUSG00000054874
AA Change: S156P
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
376 |
N/A |
INTRINSIC |
|
transmembrane domain
|
385 |
407 |
N/A |
INTRINSIC |
|
transmembrane domain
|
411 |
428 |
N/A |
INTRINSIC |
|
transmembrane domain
|
441 |
463 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
501 |
523 |
N/A |
INTRINSIC |
|
transmembrane domain
|
538 |
560 |
N/A |
INTRINSIC |
|
transmembrane domain
|
573 |
592 |
N/A |
INTRINSIC |
|
transmembrane domain
|
645 |
667 |
N/A |
INTRINSIC |
|
transmembrane domain
|
669 |
691 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1025 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1159 |
1389 |
7.5e-124 |
PFAM |
|
low complexity region
|
1462 |
1479 |
N/A |
INTRINSIC |
|
low complexity region
|
1481 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1538 |
N/A |
INTRINSIC |
|
low complexity region
|
1558 |
1569 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113615
AA Change: S156P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000109245
Gene: ENSMUSG00000054874
AA Change: S156P
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
459 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
784 |
N/A |
INTRINSIC |
|
transmembrane domain
|
793 |
815 |
N/A |
INTRINSIC |
|
transmembrane domain
|
819 |
836 |
N/A |
INTRINSIC |
|
transmembrane domain
|
849 |
871 |
N/A |
INTRINSIC |
|
transmembrane domain
|
881 |
900 |
N/A |
INTRINSIC |
|
transmembrane domain
|
909 |
931 |
N/A |
INTRINSIC |
|
transmembrane domain
|
946 |
968 |
N/A |
INTRINSIC |
|
transmembrane domain
|
981 |
1000 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1053 |
1075 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1077 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1433 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1570 |
1796 |
5.9e-116 |
PFAM |
|
low complexity region
|
1870 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1918 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1946 |
N/A |
INTRINSIC |
|
low complexity region
|
1966 |
1977 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000127876
|
| SMART Domains |
Protein: ENSMUSP00000123696
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
69 |
75 |
N/A |
INTRINSIC |
|
transmembrane domain
|
84 |
106 |
N/A |
INTRINSIC |
|
transmembrane domain
|
110 |
127 |
N/A |
INTRINSIC |
|
transmembrane domain
|
140 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
172 |
191 |
N/A |
INTRINSIC |
|
transmembrane domain
|
200 |
222 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141577
|
| SMART Domains |
Protein: ENSMUSP00000116451
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
110 |
N/A |
INTRINSIC |
|
transmembrane domain
|
119 |
141 |
N/A |
INTRINSIC |
|
transmembrane domain
|
145 |
162 |
N/A |
INTRINSIC |
|
transmembrane domain
|
175 |
197 |
N/A |
INTRINSIC |
|
transmembrane domain
|
207 |
224 |
N/A |
INTRINSIC |
|
transmembrane domain
|
229 |
251 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145270
|
| SMART Domains |
Protein: ENSMUSP00000116493
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
199 |
205 |
N/A |
INTRINSIC |
|
transmembrane domain
|
214 |
236 |
N/A |
INTRINSIC |
|
transmembrane domain
|
240 |
257 |
N/A |
INTRINSIC |
|
transmembrane domain
|
270 |
292 |
N/A |
INTRINSIC |
|
transmembrane domain
|
302 |
321 |
N/A |
INTRINSIC |
|
transmembrane domain
|
330 |
352 |
N/A |
INTRINSIC |
|
transmembrane domain
|
367 |
389 |
N/A |
INTRINSIC |
|
transmembrane domain
|
402 |
421 |
N/A |
INTRINSIC |
|
transmembrane domain
|
474 |
496 |
N/A |
INTRINSIC |
|
transmembrane domain
|
498 |
520 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc6 |
C |
T |
7: 45,629,449 (GRCm39) |
V1293M |
probably damaging |
Het |
| Agt |
A |
G |
8: 125,290,537 (GRCm39) |
W257R |
possibly damaging |
Het |
| Arhgef11 |
T |
A |
3: 87,620,406 (GRCm39) |
N457K |
probably benign |
Het |
| Bcl3 |
G |
T |
7: 19,554,082 (GRCm39) |
H95Q |
probably benign |
Het |
| C1d |
T |
A |
11: 17,213,662 (GRCm39) |
N64K |
probably damaging |
Het |
| Casc3 |
C |
T |
11: 98,713,607 (GRCm39) |
R280C |
probably damaging |
Het |
| Cd300c2 |
C |
T |
11: 114,891,466 (GRCm39) |
S136N |
probably benign |
Het |
| Cdh8 |
A |
G |
8: 99,757,672 (GRCm39) |
V642A |
possibly damaging |
Het |
| Cep290 |
A |
T |
10: 100,331,706 (GRCm39) |
I180F |
possibly damaging |
Het |
| Copz2 |
A |
G |
11: 96,744,887 (GRCm39) |
E86G |
probably damaging |
Het |
| Cplane1 |
A |
G |
15: 8,230,635 (GRCm39) |
I971V |
probably benign |
Het |
| Cracdl |
A |
G |
1: 37,652,537 (GRCm39) |
V1090A |
probably benign |
Het |
| Csf3r |
A |
T |
4: 125,923,712 (GRCm39) |
D74V |
possibly damaging |
Het |
| Cyp11b1 |
T |
G |
15: 74,710,789 (GRCm39) |
E257A |
possibly damaging |
Het |
| Dlg2 |
A |
G |
7: 92,024,875 (GRCm39) |
Q580R |
probably damaging |
Het |
| Dnai2 |
A |
T |
11: 114,645,275 (GRCm39) |
K570M |
unknown |
Het |
| Dock8 |
A |
G |
19: 25,133,281 (GRCm39) |
K1143E |
probably benign |
Het |
| Dxo |
T |
C |
17: 35,058,099 (GRCm39) |
S394P |
probably benign |
Het |
| Etl4 |
A |
G |
2: 20,810,977 (GRCm39) |
D1388G |
probably benign |
Het |
| F13a1 |
C |
A |
13: 37,209,692 (GRCm39) |
R91L |
probably damaging |
Het |
| Fam50b |
C |
T |
13: 34,930,856 (GRCm39) |
R111* |
probably null |
Het |
| Fat2 |
T |
G |
11: 55,202,535 (GRCm39) |
N180H |
probably damaging |
Het |
| Fitm2 |
A |
T |
2: 163,311,768 (GRCm39) |
H148Q |
probably benign |
Het |
| Fjx1 |
A |
T |
2: 102,281,156 (GRCm39) |
S260T |
possibly damaging |
Het |
| Fos |
T |
C |
12: 85,522,466 (GRCm39) |
L165P |
probably damaging |
Het |
| Gm39115 |
C |
A |
7: 141,689,710 (GRCm39) |
C21F |
unknown |
Het |
| Gucy1a1 |
C |
T |
3: 82,005,000 (GRCm39) |
C595Y |
probably damaging |
Het |
| Hectd4 |
G |
T |
5: 121,467,172 (GRCm39) |
W2478L |
possibly damaging |
Het |
| I830077J02Rik |
T |
A |
3: 105,836,060 (GRCm39) |
K9N |
probably damaging |
Het |
| Ift70a1 |
T |
C |
2: 75,811,519 (GRCm39) |
D188G |
probably benign |
Het |
| Ireb2 |
T |
C |
9: 54,811,265 (GRCm39) |
F723L |
possibly damaging |
Het |
| Itpr1 |
G |
A |
6: 108,496,309 (GRCm39) |
V2580I |
probably damaging |
Het |
| Kcnu1 |
G |
A |
8: 26,382,092 (GRCm39) |
G481R |
probably damaging |
Het |
| Kdm3b |
G |
T |
18: 34,926,129 (GRCm39) |
A90S |
probably benign |
Het |
| Klra8 |
A |
G |
6: 130,105,056 (GRCm39) |
V23A |
probably damaging |
Het |
| Lig4 |
A |
G |
8: 10,023,777 (GRCm39) |
M1T |
probably null |
Het |
| Lpin3 |
C |
T |
2: 160,737,273 (GRCm39) |
P107S |
probably damaging |
Het |
| Lrp1b |
T |
A |
2: 41,265,867 (GRCm39) |
K1100* |
probably null |
Het |
| Obscn |
G |
A |
11: 58,929,700 (GRCm39) |
H5172Y |
probably damaging |
Het |
| Or10a3m |
T |
A |
7: 108,313,418 (GRCm39) |
M286K |
possibly damaging |
Het |
| Or4p20 |
A |
G |
2: 88,253,745 (GRCm39) |
I208T |
probably benign |
Het |
| Or5ae1 |
C |
T |
7: 84,565,787 (GRCm39) |
H267Y |
probably benign |
Het |
| Or6z1 |
T |
A |
7: 6,504,734 (GRCm39) |
T170S |
probably damaging |
Het |
| Or8c14-ps1 |
A |
T |
9: 38,101,498 (GRCm39) |
H159L |
possibly damaging |
Het |
| Orc3 |
A |
G |
4: 34,593,173 (GRCm39) |
L298P |
probably damaging |
Het |
| Otub1 |
A |
G |
19: 7,177,360 (GRCm39) |
F96L |
probably damaging |
Het |
| Pde3b |
A |
G |
7: 114,126,129 (GRCm39) |
M788V |
probably damaging |
Het |
| Pias4 |
A |
G |
10: 80,992,844 (GRCm39) |
|
probably null |
Het |
| Polg |
A |
G |
7: 79,114,743 (GRCm39) |
C73R |
probably benign |
Het |
| Ptbp2 |
T |
C |
3: 119,541,467 (GRCm39) |
Y190C |
probably damaging |
Het |
| Rab33b |
T |
A |
3: 51,401,050 (GRCm39) |
F175I |
probably damaging |
Het |
| Rfx1 |
A |
G |
8: 84,806,515 (GRCm39) |
T108A |
probably benign |
Het |
| Ribc2 |
A |
G |
15: 85,019,461 (GRCm39) |
D81G |
probably benign |
Het |
| Rnf213 |
T |
G |
11: 119,340,149 (GRCm39) |
M3460R |
|
Het |
| Rsf1 |
T |
A |
7: 97,266,103 (GRCm39) |
S86T |
|
Het |
| Rxfp2 |
C |
A |
5: 149,973,068 (GRCm39) |
T181N |
possibly damaging |
Het |
| Samm50 |
G |
A |
15: 84,094,702 (GRCm39) |
E365K |
possibly damaging |
Het |
| Shld2 |
A |
C |
14: 33,989,942 (GRCm39) |
N321K |
probably benign |
Het |
| Slc22a18 |
T |
C |
7: 143,051,123 (GRCm39) |
V334A |
probably damaging |
Het |
| Slc23a3 |
A |
T |
1: 75,110,085 (GRCm39) |
C97S |
probably benign |
Het |
| Smchd1 |
T |
A |
17: 71,714,244 (GRCm39) |
H873L |
probably benign |
Het |
| Snrpa1 |
G |
A |
7: 65,720,381 (GRCm39) |
G195R |
probably benign |
Het |
| Sphkap |
T |
A |
1: 83,255,953 (GRCm39) |
I599F |
probably benign |
Het |
| Stox1 |
A |
G |
10: 62,501,543 (GRCm39) |
V339A |
probably damaging |
Het |
| Tlx1 |
A |
G |
19: 45,142,036 (GRCm39) |
E220G |
probably damaging |
Het |
| Tmem71 |
C |
A |
15: 66,413,421 (GRCm39) |
|
probably null |
Het |
| Tmprss3 |
T |
C |
17: 31,413,976 (GRCm39) |
D56G |
possibly damaging |
Het |
| Trabd |
A |
G |
15: 88,970,107 (GRCm39) |
R368G |
probably benign |
Het |
| Trf |
A |
G |
9: 103,094,675 (GRCm39) |
I461T |
probably damaging |
Het |
| Trpm3 |
A |
G |
19: 22,676,226 (GRCm39) |
T133A |
possibly damaging |
Het |
| Trpv3 |
G |
A |
11: 73,186,209 (GRCm39) |
V667I |
possibly damaging |
Het |
| Vps13b |
T |
A |
15: 35,455,246 (GRCm39) |
N718K |
probably benign |
Het |
| Zdbf2 |
T |
C |
1: 63,345,166 (GRCm39) |
S1182P |
possibly damaging |
Het |
| Zfp13 |
T |
C |
17: 23,795,866 (GRCm39) |
D235G |
probably benign |
Het |
| Zfp407 |
T |
C |
18: 84,227,987 (GRCm39) |
E1874G |
probably damaging |
Het |
| Zfp503 |
T |
C |
14: 22,036,277 (GRCm39) |
K213R |
probably benign |
Het |
| Zkscan2 |
A |
G |
7: 123,084,651 (GRCm39) |
V491A |
probably damaging |
Het |
|
| Other mutations in Pcnx3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01616:Pcnx3
|
APN |
19 |
5,717,287 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01667:Pcnx3
|
APN |
19 |
5,736,658 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01704:Pcnx3
|
APN |
19 |
5,717,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01752:Pcnx3
|
APN |
19 |
5,715,365 (GRCm39) |
nonsense |
probably null |
|
|
IGL01791:Pcnx3
|
APN |
19 |
5,723,295 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL01937:Pcnx3
|
APN |
19 |
5,727,691 (GRCm39) |
missense |
probably benign |
|
|
IGL01987:Pcnx3
|
APN |
19 |
5,727,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Pcnx3
|
APN |
19 |
5,729,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02417:Pcnx3
|
APN |
19 |
5,736,509 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03143:Pcnx3
|
APN |
19 |
5,735,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
buns
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
Pastries
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
pie
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7096_pcnx3_526
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
swirls
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
tip
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
PIT4453001:Pcnx3
|
UTSW |
19 |
5,722,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0360:Pcnx3
|
UTSW |
19 |
5,715,611 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0687:Pcnx3
|
UTSW |
19 |
5,734,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0718:Pcnx3
|
UTSW |
19 |
5,727,756 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pcnx3
|
UTSW |
19 |
5,735,729 (GRCm39) |
splice site |
probably null |
|
|
R0907:Pcnx3
|
UTSW |
19 |
5,721,553 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1251:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1373:Pcnx3
|
UTSW |
19 |
5,715,544 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1572:Pcnx3
|
UTSW |
19 |
5,735,375 (GRCm39) |
nonsense |
probably null |
|
|
R1602:Pcnx3
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1628:Pcnx3
|
UTSW |
19 |
5,736,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1635:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1670:Pcnx3
|
UTSW |
19 |
5,723,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Pcnx3
|
UTSW |
19 |
5,722,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1898:Pcnx3
|
UTSW |
19 |
5,722,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Pcnx3
|
UTSW |
19 |
5,721,584 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2147:Pcnx3
|
UTSW |
19 |
5,717,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R2871:Pcnx3
|
UTSW |
19 |
5,733,774 (GRCm39) |
intron |
probably benign |
|
|
R3699:Pcnx3
|
UTSW |
19 |
5,722,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Pcnx3
|
UTSW |
19 |
5,728,696 (GRCm39) |
nonsense |
probably null |
|
|
R3856:Pcnx3
|
UTSW |
19 |
5,728,995 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3953:Pcnx3
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
R4613:Pcnx3
|
UTSW |
19 |
5,717,247 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4781:Pcnx3
|
UTSW |
19 |
5,737,158 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4816:Pcnx3
|
UTSW |
19 |
5,738,023 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Pcnx3
|
UTSW |
19 |
5,722,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Pcnx3
|
UTSW |
19 |
5,731,607 (GRCm39) |
intron |
probably benign |
|
|
R5950:Pcnx3
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5951:Pcnx3
|
UTSW |
19 |
5,721,708 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5969:Pcnx3
|
UTSW |
19 |
5,735,563 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6543:Pcnx3
|
UTSW |
19 |
5,715,275 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6704:Pcnx3
|
UTSW |
19 |
5,736,515 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7096:Pcnx3
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Pcnx3
|
UTSW |
19 |
5,737,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7308:Pcnx3
|
UTSW |
19 |
5,736,175 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7387:Pcnx3
|
UTSW |
19 |
5,723,364 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7488:Pcnx3
|
UTSW |
19 |
5,717,487 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7670:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7831:Pcnx3
|
UTSW |
19 |
5,735,989 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7850:Pcnx3
|
UTSW |
19 |
5,728,960 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8120:Pcnx3
|
UTSW |
19 |
5,717,574 (GRCm39) |
missense |
probably benign |
|
|
R8139:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8258:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8259:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8411:Pcnx3
|
UTSW |
19 |
5,729,618 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8429:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8431:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8450:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Pcnx3
|
UTSW |
19 |
5,725,404 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8790:Pcnx3
|
UTSW |
19 |
5,735,206 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8939:Pcnx3
|
UTSW |
19 |
5,730,347 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9065:Pcnx3
|
UTSW |
19 |
5,717,582 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9070:Pcnx3
|
UTSW |
19 |
5,715,601 (GRCm39) |
missense |
probably benign |
0.33 |
|
X0028:Pcnx3
|
UTSW |
19 |
5,734,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0053:Pcnx3
|
UTSW |
19 |
5,736,650 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Pcnx3
|
UTSW |
19 |
5,737,248 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Pcnx3
|
UTSW |
19 |
5,721,654 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCTCGATCGGCAGAGGTC -3'
(R):5'- AACCAGGTTTCGGTGAGTAGG -3'
Sequencing Primer
(F):5'- ATCGGCAGAGGTCACGATCAC -3'
(R):5'- TTTCGGTGAGTAGGCTCCCC -3'
|
| Posted On |
2020-10-20 |
Incidental Mutation