Incidental Mutation 'R8465:Obsl1'
| ID |
656734 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Obsl1
|
| Ensembl Gene |
ENSMUSG00000026211 |
| Gene Name |
obscurin-like 1 |
| Synonyms |
|
| MMRRC Submission |
067909-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.269)
|
| Stock # |
R8465 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
75462469-75483134 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 75480032 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 310
(T310A)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037330]
[ENSMUST00000113565]
[ENSMUST00000113567]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037330
|
| SMART Domains |
Protein: ENSMUSP00000040310
Gene: ENSMUSG00000032968
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
189 |
199 |
N/A |
INTRINSIC |
|
TGFB
|
263 |
366 |
1.58e-25 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113565
AA Change: T505A
PolyPhen 2
Score 0.524 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000109195
Gene: ENSMUSG00000026211
AA Change: T505A
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
5e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
2e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113567
AA Change: T505A
PolyPhen 2
Score 0.833 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000109197
Gene: ENSMUSG00000026211
AA Change: T505A
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
8e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
3e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
IG
|
996 |
1075 |
1.27e-5 |
SMART |
|
IGc2
|
1094 |
1160 |
4.07e-4 |
SMART |
|
IGc2
|
1186 |
1252 |
9.49e-5 |
SMART |
|
IG
|
1274 |
1353 |
7.41e-7 |
SMART |
|
IG
|
1363 |
1444 |
1.15e-3 |
SMART |
|
IG
|
1454 |
1533 |
8.33e-1 |
SMART |
|
IGc2
|
1549 |
1615 |
8.72e-4 |
SMART |
|
IG
|
1633 |
1712 |
1e-3 |
SMART |
|
IG
|
1723 |
1802 |
3.82e-9 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000155084
AA Change: T310A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000114553
Gene: ENSMUSG00000026211
AA Change: T310A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1g1ca_
|
2 |
32 |
1e-3 |
SMART |
|
IGc2
|
64 |
132 |
1.48e-6 |
SMART |
|
IG
|
153 |
233 |
9.49e-5 |
SMART |
|
IG
|
241 |
317 |
1.04e-1 |
SMART |
|
FN3
|
324 |
407 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
414 |
520 |
4e-57 |
PDB |
|
Blast:IG_like
|
428 |
517 |
2e-50 |
BLAST |
|
IG
|
529 |
610 |
3.79e-4 |
SMART |
|
IG
|
620 |
699 |
2.58e-6 |
SMART |
|
IGc2
|
717 |
783 |
1.12e-6 |
SMART |
|
IG
|
802 |
881 |
1.27e-5 |
SMART |
|
IGc2
|
900 |
966 |
4.07e-4 |
SMART |
|
IGc2
|
992 |
1058 |
9.49e-5 |
SMART |
|
IG
|
1080 |
1159 |
7.41e-7 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (80/80) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acot6 |
A |
T |
12: 84,153,215 (GRCm39) |
|
probably null |
Het |
| Adamtsl3 |
A |
T |
7: 82,247,330 (GRCm39) |
N1429Y |
probably benign |
Het |
| Adk |
T |
C |
14: 21,153,892 (GRCm39) |
S32P |
possibly damaging |
Het |
| Akap13 |
A |
T |
7: 75,376,786 (GRCm39) |
M2005L |
probably benign |
Het |
| Atp10a |
A |
T |
7: 58,478,058 (GRCm39) |
D1367V |
probably benign |
Het |
| Bckdhb |
A |
G |
9: 83,870,915 (GRCm39) |
I142V |
probably benign |
Het |
| Brap |
C |
T |
5: 121,817,358 (GRCm39) |
Q322* |
probably null |
Het |
| Carmil3 |
A |
T |
14: 55,734,305 (GRCm39) |
N401I |
probably damaging |
Het |
| Cdan1 |
A |
T |
2: 120,558,921 (GRCm39) |
S426T |
possibly damaging |
Het |
| Cdc27 |
C |
A |
11: 104,408,317 (GRCm39) |
S531I |
probably benign |
Het |
| Cela3a |
A |
T |
4: 137,131,185 (GRCm39) |
Y184* |
probably null |
Het |
| Cep63 |
T |
C |
9: 102,490,576 (GRCm39) |
K178R |
probably benign |
Het |
| Cfb |
G |
A |
17: 35,076,290 (GRCm39) |
Q152* |
probably null |
Het |
| Cnpy2 |
G |
A |
10: 128,162,044 (GRCm39) |
V106I |
probably benign |
Het |
| Cntn1 |
GCTGTCTTC |
GC |
15: 92,237,404 (GRCm39) |
|
probably null |
Het |
| Ctc1 |
G |
A |
11: 68,917,045 (GRCm39) |
G67D |
probably damaging |
Het |
| Cwc27 |
G |
T |
13: 104,940,772 (GRCm39) |
P196T |
probably benign |
Het |
| Cwc27 |
C |
A |
13: 104,940,776 (GRCm39) |
L194F |
possibly damaging |
Het |
| Cyp2d12 |
T |
G |
15: 82,439,378 (GRCm39) |
S11A |
possibly damaging |
Het |
| Ddx55 |
T |
A |
5: 124,697,184 (GRCm39) |
|
probably null |
Het |
| Dedd2 |
G |
T |
7: 24,918,331 (GRCm39) |
R75S |
probably damaging |
Het |
| Fat2 |
G |
A |
11: 55,147,530 (GRCm39) |
S3904F |
possibly damaging |
Het |
| Fibp |
G |
A |
19: 5,513,215 (GRCm39) |
V177I |
probably damaging |
Het |
| Fsip2 |
A |
T |
2: 82,810,284 (GRCm39) |
E2201V |
probably benign |
Het |
| Gbp11 |
C |
T |
5: 105,472,928 (GRCm39) |
D499N |
probably benign |
Het |
| Gfm1 |
A |
G |
3: 67,339,032 (GRCm39) |
E45G |
probably damaging |
Het |
| H2-D1 |
A |
G |
17: 35,482,487 (GRCm39) |
Y69C |
probably damaging |
Het |
| Hcar1 |
A |
G |
5: 124,017,109 (GRCm39) |
F194S |
probably damaging |
Het |
| Heatr4 |
A |
T |
12: 84,024,707 (GRCm39) |
|
probably null |
Het |
| Kcnd2 |
G |
A |
6: 21,216,695 (GRCm39) |
C133Y |
probably damaging |
Het |
| Kcnq1 |
A |
T |
7: 142,979,711 (GRCm39) |
Q619L |
probably benign |
Het |
| Kctd12 |
T |
A |
14: 103,218,901 (GRCm39) |
R326W |
probably damaging |
Het |
| Kel |
A |
G |
6: 41,666,472 (GRCm39) |
|
probably null |
Het |
| Lipk |
A |
T |
19: 34,024,197 (GRCm39) |
I332F |
probably benign |
Het |
| Lrrc37 |
T |
A |
11: 103,506,947 (GRCm39) |
|
probably benign |
Het |
| Masp2 |
A |
G |
4: 148,696,516 (GRCm39) |
D371G |
possibly damaging |
Het |
| Met |
A |
G |
6: 17,571,809 (GRCm39) |
E1376G |
probably benign |
Het |
| Mup5 |
A |
T |
4: 61,752,015 (GRCm39) |
I78K |
probably benign |
Het |
| Mynn |
A |
T |
3: 30,670,790 (GRCm39) |
D526V |
probably damaging |
Het |
| Naip6 |
G |
T |
13: 100,433,423 (GRCm39) |
T1138N |
possibly damaging |
Het |
| Neurod1 |
G |
T |
2: 79,284,696 (GRCm39) |
P229Q |
probably damaging |
Het |
| Npepps |
T |
G |
11: 97,139,085 (GRCm39) |
R162S |
probably damaging |
Het |
| Ntrk3 |
T |
A |
7: 78,112,631 (GRCm39) |
Q175L |
probably damaging |
Het |
| Or4g7 |
A |
T |
2: 111,309,425 (GRCm39) |
T99S |
probably benign |
Het |
| Or8c9 |
A |
T |
9: 38,241,410 (GRCm39) |
I176F |
possibly damaging |
Het |
| Or8j3c |
A |
T |
2: 86,253,975 (GRCm39) |
M15K |
probably benign |
Het |
| Or8k32 |
A |
G |
2: 86,368,731 (GRCm39) |
I176T |
probably damaging |
Het |
| Pigf |
G |
A |
17: 87,304,964 (GRCm39) |
T193I |
possibly damaging |
Het |
| Pkp4 |
T |
C |
2: 59,172,525 (GRCm39) |
V904A |
possibly damaging |
Het |
| Plekha6 |
C |
T |
1: 133,197,778 (GRCm39) |
T141M |
probably damaging |
Het |
| Rapgef6 |
G |
A |
11: 54,582,308 (GRCm39) |
D1407N |
probably benign |
Het |
| Rhobtb3 |
T |
C |
13: 76,087,741 (GRCm39) |
D82G |
probably damaging |
Het |
| Rims1 |
T |
C |
1: 22,498,731 (GRCm39) |
N767S |
possibly damaging |
Het |
| Ripor2 |
T |
A |
13: 24,849,451 (GRCm39) |
|
probably benign |
Het |
| Sec14l4 |
T |
A |
11: 3,993,948 (GRCm39) |
I296N |
probably damaging |
Het |
| Serpinb12 |
G |
T |
1: 106,884,342 (GRCm39) |
V363F |
probably damaging |
Het |
| Serpinb9c |
A |
G |
13: 33,334,016 (GRCm39) |
I342T |
probably damaging |
Het |
| Shmt2 |
A |
G |
10: 127,355,945 (GRCm39) |
V133A |
probably damaging |
Het |
| Slc30a6 |
A |
G |
17: 74,722,661 (GRCm39) |
M243V |
probably benign |
Het |
| Slfn2 |
T |
A |
11: 82,960,487 (GRCm39) |
N155K |
probably damaging |
Het |
| Spata31h1 |
A |
T |
10: 82,152,298 (GRCm39) |
L23M |
possibly damaging |
Het |
| Syne2 |
A |
T |
12: 75,900,898 (GRCm39) |
D19V |
possibly damaging |
Het |
| Tcl1b3 |
A |
T |
12: 105,160,736 (GRCm39) |
I116L |
probably benign |
Het |
| Tcp11 |
A |
G |
17: 28,286,766 (GRCm39) |
I411T |
probably damaging |
Het |
| Tctn1 |
C |
T |
5: 122,379,859 (GRCm39) |
A560T |
probably benign |
Het |
| Tenm3 |
C |
A |
8: 48,682,216 (GRCm39) |
Q2471H |
probably damaging |
Het |
| Tnr |
A |
G |
1: 159,713,645 (GRCm39) |
D691G |
probably benign |
Het |
| Ube3b |
C |
T |
5: 114,528,451 (GRCm39) |
P150S |
probably damaging |
Het |
| Ugt2b5 |
T |
C |
5: 87,287,518 (GRCm39) |
I216M |
possibly damaging |
Het |
| Unc5d |
T |
A |
8: 29,156,877 (GRCm39) |
R789S |
probably damaging |
Het |
| Ush2a |
G |
A |
1: 188,147,875 (GRCm39) |
G934D |
probably damaging |
Het |
| Usp6nl |
A |
T |
2: 6,399,352 (GRCm39) |
R70S |
probably damaging |
Het |
| Vmn1r181 |
T |
C |
7: 23,684,309 (GRCm39) |
I258T |
possibly damaging |
Het |
| Vmn2r15 |
C |
A |
5: 109,445,302 (GRCm39) |
D41Y |
probably damaging |
Het |
| Vmn2r17 |
T |
A |
5: 109,600,691 (GRCm39) |
I663N |
probably damaging |
Het |
| Vnn3 |
C |
A |
10: 23,741,780 (GRCm39) |
Q362K |
possibly damaging |
Het |
| Wdr72 |
A |
G |
9: 74,059,730 (GRCm39) |
D380G |
possibly damaging |
Het |
| Wfdc10 |
G |
A |
2: 164,499,180 (GRCm39) |
E97K |
possibly damaging |
Het |
| Xdh |
A |
T |
17: 74,206,007 (GRCm39) |
C1002* |
probably null |
Het |
| Zscan4e |
A |
C |
7: 11,041,578 (GRCm39) |
V126G |
probably damaging |
Het |
|
| Other mutations in Obsl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Obsl1
|
APN |
1 |
75,467,518 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01111:Obsl1
|
APN |
1 |
75,473,789 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01140:Obsl1
|
APN |
1 |
75,466,400 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02149:Obsl1
|
APN |
1 |
75,480,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Obsl1
|
APN |
1 |
75,480,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02269:Obsl1
|
APN |
1 |
75,464,357 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02296:Obsl1
|
APN |
1 |
75,474,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02386:Obsl1
|
APN |
1 |
75,469,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Obsl1
|
APN |
1 |
75,481,890 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02601:Obsl1
|
APN |
1 |
75,466,264 (GRCm39) |
missense |
probably benign |
|
|
IGL03053:Obsl1
|
APN |
1 |
75,469,723 (GRCm39) |
missense |
probably benign |
|
|
IGL03181:Obsl1
|
APN |
1 |
75,469,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03402:Obsl1
|
APN |
1 |
75,463,443 (GRCm39) |
missense |
probably benign |
0.00 |
|
Jude
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Obsl1
|
UTSW |
1 |
75,482,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4382001:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0281:Obsl1
|
UTSW |
1 |
75,469,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1343:Obsl1
|
UTSW |
1 |
75,469,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1394:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1395:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1439:Obsl1
|
UTSW |
1 |
75,463,428 (GRCm39) |
nonsense |
probably null |
|
|
R1456:Obsl1
|
UTSW |
1 |
75,464,300 (GRCm39) |
nonsense |
probably null |
|
|
R1728:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1729:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1730:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1739:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1757:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R1762:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1783:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1784:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1785:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1851:Obsl1
|
UTSW |
1 |
75,469,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Obsl1
|
UTSW |
1 |
75,469,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1873:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1980:Obsl1
|
UTSW |
1 |
75,482,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1985:Obsl1
|
UTSW |
1 |
75,482,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2069:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2122:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R2141:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2142:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2184:Obsl1
|
UTSW |
1 |
75,478,861 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2267:Obsl1
|
UTSW |
1 |
75,482,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2883:Obsl1
|
UTSW |
1 |
75,473,155 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3079:Obsl1
|
UTSW |
1 |
75,467,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Obsl1
|
UTSW |
1 |
75,474,890 (GRCm39) |
missense |
probably benign |
|
|
R4002:Obsl1
|
UTSW |
1 |
75,476,743 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4365:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4366:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4414:Obsl1
|
UTSW |
1 |
75,467,546 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4700:Obsl1
|
UTSW |
1 |
75,480,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Obsl1
|
UTSW |
1 |
75,466,145 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5081:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R5389:Obsl1
|
UTSW |
1 |
75,479,905 (GRCm39) |
intron |
probably benign |
|
|
R5757:Obsl1
|
UTSW |
1 |
75,469,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5890:Obsl1
|
UTSW |
1 |
75,470,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5946:Obsl1
|
UTSW |
1 |
75,467,851 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6005:Obsl1
|
UTSW |
1 |
75,468,859 (GRCm39) |
splice site |
probably null |
|
|
R6118:Obsl1
|
UTSW |
1 |
75,468,722 (GRCm39) |
intron |
probably benign |
|
|
R6154:Obsl1
|
UTSW |
1 |
75,476,788 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6317:Obsl1
|
UTSW |
1 |
75,466,273 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6379:Obsl1
|
UTSW |
1 |
75,479,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6387:Obsl1
|
UTSW |
1 |
75,468,006 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7084:Obsl1
|
UTSW |
1 |
75,464,394 (GRCm39) |
missense |
probably benign |
|
|
R7123:Obsl1
|
UTSW |
1 |
75,466,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7202:Obsl1
|
UTSW |
1 |
75,466,360 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7291:Obsl1
|
UTSW |
1 |
75,466,161 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7305:Obsl1
|
UTSW |
1 |
75,470,590 (GRCm39) |
nonsense |
probably null |
|
|
R7366:Obsl1
|
UTSW |
1 |
75,479,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Obsl1
|
UTSW |
1 |
75,464,348 (GRCm39) |
missense |
probably benign |
|
|
R7474:Obsl1
|
UTSW |
1 |
75,474,828 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7611:Obsl1
|
UTSW |
1 |
75,482,024 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7672:Obsl1
|
UTSW |
1 |
75,469,365 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7715:Obsl1
|
UTSW |
1 |
75,478,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7762:Obsl1
|
UTSW |
1 |
75,480,167 (GRCm39) |
missense |
probably benign |
|
|
R8005:Obsl1
|
UTSW |
1 |
75,482,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8012:Obsl1
|
UTSW |
1 |
75,469,317 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8379:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8381:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8383:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8396:Obsl1
|
UTSW |
1 |
75,480,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8506:Obsl1
|
UTSW |
1 |
75,482,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8710:Obsl1
|
UTSW |
1 |
75,469,326 (GRCm39) |
missense |
probably benign |
|
|
R8877:Obsl1
|
UTSW |
1 |
75,473,167 (GRCm39) |
nonsense |
probably null |
|
|
R8903:Obsl1
|
UTSW |
1 |
75,463,917 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8913:Obsl1
|
UTSW |
1 |
75,467,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8924:Obsl1
|
UTSW |
1 |
75,482,841 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8955:Obsl1
|
UTSW |
1 |
75,480,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9008:Obsl1
|
UTSW |
1 |
75,482,027 (GRCm39) |
missense |
probably benign |
|
|
R9121:Obsl1
|
UTSW |
1 |
75,482,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9295:Obsl1
|
UTSW |
1 |
75,476,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Obsl1
|
UTSW |
1 |
75,482,391 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9367:Obsl1
|
UTSW |
1 |
75,466,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9459:Obsl1
|
UTSW |
1 |
75,474,884 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9496:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9497:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Obsl1
|
UTSW |
1 |
75,466,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9546:Obsl1
|
UTSW |
1 |
75,482,030 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9550:Obsl1
|
UTSW |
1 |
75,474,910 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9561:Obsl1
|
UTSW |
1 |
75,480,157 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9687:Obsl1
|
UTSW |
1 |
75,479,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V8831:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
X0061:Obsl1
|
UTSW |
1 |
75,463,412 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,467,656 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1177:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,480,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCCTTTGAACATCTCAACC -3'
(R):5'- AGTACTGCTGGTGGAGACTCAAG -3'
Sequencing Primer
(F):5'- CTTTGAACATCTCAACCATTACGGGG -3'
(R):5'- CTCAAGAAGCTGGGGTGC -3'
|
| Posted On |
2021-01-18 |
Incidental Mutation