Mutagenetix > Incidental Mutation

Incidental Mutation 'R8470:Pcdha11'

657010

Institutional Source

Beutler Lab

Gene Symbol

Pcdha11

Ensembl Gene

ENSMUSG00000102206

Gene Name

protocadherin alpha 11

Synonyms

A830022B16Rik, Cnr7, Crnr7

MMRRC Submission

067914-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.133) question?

Stock #

R8470 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

37143911-37320710 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 37145937 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Arginine at position 676 (K676R)

Ref Sequence

ENSEMBL: ENSMUSP00000142270 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000070797] [ENSMUST00000115657] [ENSMUST00000115658] [ENSMUST00000115659] [ENSMUST00000115661] [ENSMUST00000115662] [ENSMUST00000192168] [ENSMUST00000192295] [ENSMUST00000192447] [ENSMUST00000192503] [ENSMUST00000192512] [ENSMUST00000192631] [ENSMUST00000193389] [ENSMUST00000193777] [ENSMUST00000193839] [ENSMUST00000194038] [ENSMUST00000194544] [ENSMUST00000194751] [ENSMUST00000195590]

AlphaFold

Q91Y19

Predicted Effect

probably benign
Transcript: ENSMUST00000070797

SMART Domains

Protein: ENSMUSP00000068828
Gene: ENSMUSG00000103442

Domain	Start	End	E-Value	Type
CA	22	132	3.09e-2	SMART
CA	156	241	6.14e-20	SMART
CA	265	349	3.92e-27	SMART
CA	373	454	4.94e-24	SMART
CA	478	564	1e-24	SMART
CA	592	672	4.55e-14	SMART
transmembrane domain	694	716	N/A	INTRINSIC
Pfam:Cadherin_tail	797	931	5.3e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115657
AA Change: K676R

PolyPhen 2 Score 0.033 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000111321
Gene: ENSMUSG00000102206
AA Change: K676R

Domain	Start	End	E-Value	Type
CA	21	131	2.95e-2	SMART
CA	155	240	7.44e-19	SMART
CA	264	347	5.63e-28	SMART
CA	371	452	3.14e-26	SMART
CA	476	562	1.42e-24	SMART
CA	593	675	1.03e-12	SMART
transmembrane domain	697	719	N/A	INTRINSIC
low complexity region	783	794	N/A	INTRINSIC
low complexity region	918	942	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000115658

SMART Domains

Protein: ENSMUSP00000111322
Gene: ENSMUSG00000007440

Domain	Start	End	E-Value	Type
low complexity region	15	21	N/A	INTRINSIC
CA	46	132	6.34e-2	SMART
CA	156	241	4.65e-20	SMART
CA	265	349	1.25e-25	SMART
CA	373	454	9.22e-24	SMART
CA	478	564	4.3e-24	SMART
CA	595	678	5.07e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
Pfam:Cadherin_tail	795	929	5.3e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115659

SMART Domains

Protein: ENSMUSP00000111323
Gene: ENSMUSG00000103770

Domain	Start	End	E-Value	Type
low complexity region	44	51	N/A	INTRINSIC
CA	75	161	2.46e-2	SMART
CA	185	270	8.1e-20	SMART
CA	294	378	1.69e-22	SMART
CA	402	483	1.52e-24	SMART
CA	507	593	5.68e-24	SMART
CA	624	705	6.69e-12	SMART
transmembrane domain	727	749	N/A	INTRINSIC
Pfam:Cadherin_tail	828	962	5.6e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115661

SMART Domains

Protein: ENSMUSP00000111325
Gene: ENSMUSG00000103458

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	563	1.42e-24	SMART
CA	594	674	4.12e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
Pfam:Cadherin_tail	796	930	3.9e-58	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000115662

SMART Domains

Protein: ENSMUSP00000111326
Gene: ENSMUSG00000104148

Domain	Start	End	E-Value	Type
CA	45	131	6.34e-2	SMART
CA	155	240	2.98e-18	SMART
CA	264	348	2.17e-29	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	5.02e-25	SMART
CA	594	675	8.16e-16	SMART
transmembrane domain	695	717	N/A	INTRINSIC
low complexity region	916	940	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192168

SMART Domains

Protein: ENSMUSP00000142293
Gene: ENSMUSG00000103092

Domain	Start	End	E-Value	Type
CA	21	131	2.2e-2	SMART
CA	155	240	2.05e-21	SMART
CA	264	348	8.81e-21	SMART
CA	372	453	2.01e-24	SMART
CA	477	563	1.42e-24	SMART
CA	591	673	1.63e-15	SMART
transmembrane domain	693	715	N/A	INTRINSIC
low complexity region	902	926	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192295

SMART Domains

Protein: ENSMUSP00000142103
Gene: ENSMUSG00000104252

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	568	5.38e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000192447
AA Change: K676R

PolyPhen 2 Score 0.073 (Sensitivity: 0.93; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000142270
Gene: ENSMUSG00000102206
AA Change: K676R

Domain	Start	End	E-Value	Type
CA	21	131	1.5e-4	SMART
CA	155	240	3.6e-21	SMART
CA	264	347	2.8e-30	SMART
CA	371	452	1.5e-28	SMART
CA	476	562	6.8e-27	SMART
CA	593	675	4.9e-15	SMART
transmembrane domain	697	719	N/A	INTRINSIC
low complexity region	783	794	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192503

SMART Domains

Protein: ENSMUSP00000141989
Gene: ENSMUSG00000102312

Domain	Start	End	E-Value	Type
low complexity region	11	17	N/A	INTRINSIC
CA	42	128	3.78e-2	SMART
CA	152	237	8.94e-22	SMART
CA	261	345	3.74e-24	SMART
CA	369	450	1.09e-25	SMART
CA	474	560	1.42e-24	SMART
CA	588	670	2.96e-13	SMART
transmembrane domain	692	714	N/A	INTRINSIC
low complexity region	910	934	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192512

SMART Domains

Protein: ENSMUSP00000141408
Gene: ENSMUSG00000104252

Domain	Start	End	E-Value	Type
CA	20	131	5.3e-2	SMART
CA	155	240	1.51e-19	SMART
CA	264	348	7.6e-25	SMART
CA	372	453	1.42e-24	SMART
CA	477	563	1.42e-24	SMART
CA	594	674	4.12e-12	SMART
low complexity region	706	721	N/A	INTRINSIC
low complexity region	915	939	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000192631

SMART Domains

Protein: ENSMUSP00000142156
Gene: ENSMUSG00000104318

Domain	Start	End	E-Value	Type
CA	21	131	2.58e-2	SMART
CA	155	240	4.27e-19	SMART
CA	264	348	1.42e-24	SMART
CA	372	453	9.36e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	671	4.03e-6	SMART
transmembrane domain	696	718	N/A	INTRINSIC
low complexity region	905	929	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193389

SMART Domains

Protein: ENSMUSP00000141459
Gene: ENSMUSG00000103707

Domain	Start	End	E-Value	Type
CA	21	131	5.67e-2	SMART
CA	155	240	4.72e-21	SMART
CA	264	348	1.9e-25	SMART
CA	372	453	3.31e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	676	5.91e-13	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000193777

SMART Domains

Protein: ENSMUSP00000141587
Gene: ENSMUSG00000103707

Domain	Start	End	E-Value	Type
CA	21	131	5.67e-2	SMART
CA	155	240	4.72e-21	SMART
CA	264	348	1.9e-25	SMART
CA	372	453	3.31e-25	SMART
CA	477	563	1.42e-24	SMART
CA	594	676	5.91e-13	SMART
low complexity region	914	938	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193839

SMART Domains

Protein: ENSMUSP00000142308
Gene: ENSMUSG00000103442

Domain	Start	End	E-Value	Type
CA	22	132	3.09e-2	SMART
CA	156	241	6.14e-20	SMART
CA	265	349	3.92e-27	SMART
CA	373	454	4.94e-24	SMART
CA	478	564	1e-24	SMART
CA	592	672	4.55e-14	SMART
transmembrane domain	694	716	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193856

Predicted Effect

probably benign
Transcript: ENSMUST00000193984

Predicted Effect

probably benign
Transcript: ENSMUST00000194038

SMART Domains

Protein: ENSMUSP00000142159
Gene: ENSMUSG00000103800

Domain	Start	End	E-Value	Type
CA	20	131	6.34e-2	SMART
CA	155	240	4.27e-19	SMART
CA	264	348	2.04e-25	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	9.88e-24	SMART
CA	594	676	8.62e-15	SMART
transmembrane domain	699	721	N/A	INTRINSIC
low complexity region	914	938	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000194544

SMART Domains

Protein: ENSMUSP00000141847
Gene: ENSMUSG00000102836

Domain	Start	End	E-Value	Type
Blast:CA	18	66	5e-20	BLAST

Predicted Effect

probably benign
Transcript: ENSMUST00000194751

SMART Domains

Protein: ENSMUSP00000142285
Gene: ENSMUSG00000103707

Domain	Start	End	E-Value	Type
low complexity region	15	21	N/A	INTRINSIC
Pfam:Cadherin_2	29	112	4.5e-32	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000195590

SMART Domains

Protein: ENSMUSP00000141355
Gene: ENSMUSG00000104148

Domain	Start	End	E-Value	Type
CA	45	131	6.34e-2	SMART
CA	155	240	2.98e-18	SMART
CA	264	348	2.17e-29	SMART
CA	372	453	2.84e-24	SMART
CA	477	563	5.02e-25	SMART
CA	594	675	8.16e-16	SMART
transmembrane domain	695	717	N/A	INTRINSIC

Meta Mutation Damage Score

0.1591

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

100% (37/37)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abraxas2	A	T	7: 132,476,685 (GRCm39)	I142F	probably damaging	Het
Adamts16	A	G	13: 70,984,496 (GRCm39)	Y56H	probably damaging	Het
Alms1	A	G	6: 85,618,357 (GRCm39)	D2801G	probably damaging	Het
Anpep	A	G	7: 79,489,269 (GRCm39)	I301T	probably benign	Het
Atxn7l2	G	A	3: 108,114,285 (GRCm39)	T159M	probably benign	Het
B130006D01Rik	C	T	11: 95,617,175 (GRCm39)		probably benign	Het
Btf3l4b	C	A	13: 96,217,432 (GRCm39)	D136Y	possibly damaging	Het
Ccdc175	T	C	12: 72,202,392 (GRCm39)	K301R	probably damaging	Het
Cecr2	A	T	6: 120,733,894 (GRCm39)	Q627L	probably benign	Het
Cerkl	C	A	2: 79,172,751 (GRCm39)	M307I	probably benign	Het
Eif2ak4	A	G	2: 118,293,207 (GRCm39)	I1254M	probably damaging	Het
Epha3	T	C	16: 63,664,510 (GRCm39)	T37A	probably benign	Het
Fancm	T	C	12: 65,171,931 (GRCm39)	V1857A	probably damaging	Het
Gm3486	T	C	14: 41,206,538 (GRCm39)		probably null	Het
Il1r2	T	C	1: 40,162,416 (GRCm39)	V353A	probably damaging	Het
Irgq	A	T	7: 24,233,715 (GRCm39)	R519W	probably damaging	Het
Map1b	T	A	13: 99,652,950 (GRCm39)	S16C	probably damaging	Het
Myo9a	T	G	9: 59,739,573 (GRCm39)	C762G	probably damaging	Het
Nup107	A	T	10: 117,606,374 (GRCm39)	V454E	probably damaging	Het
Or10h5	A	G	17: 33,434,868 (GRCm39)	V150A	probably benign	Het
Or4p20	A	T	2: 88,254,228 (GRCm39)	I47N	probably damaging	Het
Or7g35	T	G	9: 19,496,265 (GRCm39)	L144R	probably damaging	Het
Pknox2	C	T	9: 36,834,986 (GRCm39)	R161H	probably damaging	Het
Prr5l	T	C	2: 101,547,430 (GRCm39)	N365S	probably benign	Het
Prrg4	A	G	2: 104,679,501 (GRCm39)	L8P	probably damaging	Het
Rasgrp2	T	A	19: 6,453,595 (GRCm39)		probably null	Het
Rtp4	A	T	16: 23,428,827 (GRCm39)	H30L	probably benign	Het
Rxfp2	T	G	5: 149,993,834 (GRCm39)	I632S	possibly damaging	Het
Spata31h1	A	C	10: 82,126,314 (GRCm39)	F2232C	probably damaging	Het
Sptbn1	C	A	11: 30,070,758 (GRCm39)	E1533D	possibly damaging	Het
Ssbp1	A	G	6: 40,454,941 (GRCm39)	I133M	probably damaging	Het
Stap1	A	G	5: 86,242,602 (GRCm39)	I188V	possibly damaging	Het
Topaz1	T	C	9: 122,603,173 (GRCm39)	M1040T	probably benign	Het
Trpm3	T	C	19: 22,887,501 (GRCm39)	F877L	possibly damaging	Het
Ush1c	A	G	7: 45,858,674 (GRCm39)	L538P	probably damaging	Het
Zfp518a	G	A	19: 40,904,162 (GRCm39)	A1364T	probably benign	Het

Other mutations in Pcdha11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01522:Pcdha11	APN	18	37,318,061 (GRCm39)	missense	probably damaging	1.00
IGL01843:Pcdha11	APN	18	37,145,886 (GRCm39)	missense	probably benign	0.28
R1165:Pcdha11	UTSW	18	37,140,757 (GRCm39)	intron	probably benign
R2422:Pcdha11	UTSW	18	37,140,325 (GRCm39)	missense	probably damaging	0.99
R2423:Pcdha11	UTSW	18	37,140,477 (GRCm39)	missense	possibly damaging	0.89
R2508:Pcdha11	UTSW	18	37,145,907 (GRCm39)	missense	possibly damaging	0.86
R3114:Pcdha11	UTSW	18	37,144,860 (GRCm39)	missense	probably damaging	1.00
R4173:Pcdha11	UTSW	18	37,145,676 (GRCm39)	missense	probably damaging	0.99
R4255:Pcdha11	UTSW	18	37,145,843 (GRCm39)	missense	probably benign	0.23
R4369:Pcdha11	UTSW	18	37,139,796 (GRCm39)	missense	possibly damaging	0.70
R4454:Pcdha11	UTSW	18	37,140,426 (GRCm39)	missense	probably benign	0.13
R4489:Pcdha11	UTSW	18	37,139,969 (GRCm39)	missense	possibly damaging	0.78
R4626:Pcdha11	UTSW	18	37,140,051 (GRCm39)	missense	probably damaging	1.00
R4751:Pcdha11	UTSW	18	37,139,997 (GRCm39)	missense	probably damaging	1.00
R4801:Pcdha11	UTSW	18	37,138,518 (GRCm39)	missense	probably damaging	1.00
R4802:Pcdha11	UTSW	18	37,138,518 (GRCm39)	missense	probably damaging	1.00
R4857:Pcdha11	UTSW	18	37,144,505 (GRCm39)	missense	probably benign	0.02
R4995:Pcdha11	UTSW	18	37,144,080 (GRCm39)	missense	probably benign	0.24
R5042:Pcdha11	UTSW	18	37,144,649 (GRCm39)	missense	probably damaging	1.00
R5480:Pcdha11	UTSW	18	37,138,935 (GRCm39)	missense	probably benign	0.04
R5495:Pcdha11	UTSW	18	37,144,079 (GRCm39)	missense	probably benign
R5523:Pcdha11	UTSW	18	37,145,439 (GRCm39)	missense	probably damaging	1.00
R5584:Pcdha11	UTSW	18	37,139,818 (GRCm39)	missense	probably damaging	1.00
R5682:Pcdha11	UTSW	18	37,144,502 (GRCm39)	missense	probably damaging	1.00
R5834:Pcdha11	UTSW	18	37,145,676 (GRCm39)	missense	probably damaging	0.99
R5842:Pcdha11	UTSW	18	37,144,337 (GRCm39)	missense	possibly damaging	0.85
R5859:Pcdha11	UTSW	18	37,140,336 (GRCm39)	missense	probably damaging	1.00
R6110:Pcdha11	UTSW	18	37,144,509 (GRCm39)	missense	probably damaging	1.00
R6135:Pcdha11	UTSW	18	37,138,870 (GRCm39)	missense	probably damaging	1.00
R6248:Pcdha11	UTSW	18	37,138,950 (GRCm39)	missense	probably benign	0.26
R6416:Pcdha11	UTSW	18	37,145,222 (GRCm39)	splice site	probably null
R6450:Pcdha11	UTSW	18	37,146,215 (GRCm39)	missense	probably damaging	1.00
R6594:Pcdha11	UTSW	18	37,144,235 (GRCm39)	missense	probably benign	0.04
R6631:Pcdha11	UTSW	18	37,138,844 (GRCm39)	missense	probably damaging	1.00
R6883:Pcdha11	UTSW	18	37,144,242 (GRCm39)	missense	probably damaging	1.00
R7088:Pcdha11	UTSW	18	37,138,470 (GRCm39)	missense	probably benign	0.00
R7129:Pcdha11	UTSW	18	37,140,291 (GRCm39)	missense	probably benign	0.45
R7153:Pcdha11	UTSW	18	37,144,278 (GRCm39)	missense	probably damaging	1.00
R7244:Pcdha11	UTSW	18	37,144,421 (GRCm39)	nonsense	probably null
R7295:Pcdha11	UTSW	18	37,139,979 (GRCm39)	missense	probably damaging	1.00
R7319:Pcdha11	UTSW	18	37,146,245 (GRCm39)	missense	probably benign	0.10
R7352:Pcdha11	UTSW	18	37,139,898 (GRCm39)	missense	probably damaging	1.00
R7516:Pcdha11	UTSW	18	37,144,671 (GRCm39)	missense	probably damaging	1.00
R7519:Pcdha11	UTSW	18	37,139,319 (GRCm39)	nonsense	probably null
R7660:Pcdha11	UTSW	18	37,138,904 (GRCm39)	missense	probably benign	0.17
R7677:Pcdha11	UTSW	18	37,144,605 (GRCm39)	missense	probably damaging	1.00
R7707:Pcdha11	UTSW	18	37,144,845 (GRCm39)	missense	probably benign	0.00
R7775:Pcdha11	UTSW	18	37,145,733 (GRCm39)	missense	possibly damaging	0.64
R7778:Pcdha11	UTSW	18	37,145,733 (GRCm39)	missense	possibly damaging	0.64
R7780:Pcdha11	UTSW	18	37,145,849 (GRCm39)	missense	probably damaging	0.97
R7916:Pcdha11	UTSW	18	37,140,441 (GRCm39)	missense	probably benign	0.01
R7991:Pcdha11	UTSW	18	37,145,909 (GRCm39)	missense	probably damaging	0.99
R8068:Pcdha11	UTSW	18	37,138,618 (GRCm39)	missense	probably damaging	1.00
R8220:Pcdha11	UTSW	18	37,139,624 (GRCm39)	missense	probably benign	0.01
R8252:Pcdha11	UTSW	18	37,140,590 (GRCm39)	missense	possibly damaging	0.65
R8392:Pcdha11	UTSW	18	37,139,212 (GRCm39)	nonsense	probably null
R8398:Pcdha11	UTSW	18	37,146,116 (GRCm39)	missense	possibly damaging	0.65
R8812:Pcdha11	UTSW	18	37,140,716 (GRCm39)	missense	probably benign	0.00
R8900:Pcdha11	UTSW	18	37,145,799 (GRCm39)	missense	probably damaging	1.00
R8968:Pcdha11	UTSW	18	37,145,307 (GRCm39)	missense	probably damaging	1.00
R9065:Pcdha11	UTSW	18	37,139,877 (GRCm39)	missense	possibly damaging	0.93
R9192:Pcdha11	UTSW	18	37,140,527 (GRCm39)	missense	probably benign	0.42
R9224:Pcdha11	UTSW	18	37,139,073 (GRCm39)	missense	probably damaging	0.99
R9228:Pcdha11	UTSW	18	37,144,512 (GRCm39)	missense	probably damaging	1.00
R9237:Pcdha11	UTSW	18	37,145,260 (GRCm39)	missense	probably damaging	1.00
R9336:Pcdha11	UTSW	18	37,144,514 (GRCm39)	missense	probably damaging	1.00
R9449:Pcdha11	UTSW	18	37,145,484 (GRCm39)	missense	probably damaging	1.00
R9475:Pcdha11	UTSW	18	37,140,591 (GRCm39)	missense	probably damaging	1.00
R9476:Pcdha11	UTSW	18	37,139,532 (GRCm39)	missense	probably benign	0.26
R9510:Pcdha11	UTSW	18	37,139,532 (GRCm39)	missense	probably benign	0.26
R9578:Pcdha11	UTSW	18	37,140,176 (GRCm39)	missense	probably damaging	1.00
R9654:Pcdha11	UTSW	18	37,145,333 (GRCm39)	missense	probably damaging	1.00
RF017:Pcdha11	UTSW	18	37,138,577 (GRCm39)	missense	possibly damaging	0.92
Z1177:Pcdha11	UTSW	18	37,145,976 (GRCm39)	missense	probably benign	0.43

Predicted Primers

PCR Primer
(F):5'- CTGGTTACAATGCTTGGCTGTC -3'
(R):5'- CCAGTGGCCTCATTGACCATAG -3'

Sequencing Primer
(F):5'- CAATGCTTGGCTGTCATATGAAG -3'
(R):5'- CTCATTGACCATAGGCAATGCTGAG -3'

Posted On

2021-01-18