Mutagenetix > Incidental Mutation

Incidental Mutation 'R8528:Ahnak'

658915

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein (desmoyokin)

Synonyms

1110004P15Rik, 2310047C17Rik, DY6

MMRRC Submission

068498-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.368) question?

Stock #

R8528 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

8989284-9076919 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 9007728 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Asparagine at position 2125 (K2125N)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000092956
AA Change: K2125N

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: K2125N

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 98.9%

Validation Efficiency

100% (40/40)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrb1	A	C	15: 74,575,851 (GRCm38)	I169L	possibly damaging	Het
Arl5b	T	A	2: 15,073,327 (GRCm38)		probably null	Het
BC055324	T	C	1: 163,986,083 (GRCm38)	K191E	probably damaging	Het
Ccng2	T	C	5: 93,269,305 (GRCm38)	V60A	possibly damaging	Het
Cfap65	A	G	1: 74,905,937 (GRCm38)	V1442A	possibly damaging	Het
Cyp1b1	T	A	17: 79,710,564 (GRCm38)	E387D	probably damaging	Het
Dchs2	T	C	3: 83,354,611 (GRCm38)	S2729P	probably damaging	Het
Dnah11	A	G	12: 118,008,803 (GRCm38)	F2882S	probably damaging	Het
Dpy30	T	C	17: 74,299,762 (GRCm38)	D97G	probably benign	Het
Enam	T	A	5: 88,502,219 (GRCm38)	V454E	probably damaging	Het
Eppk1	C	T	15: 76,110,119 (GRCm38)	R854Q	probably benign	Het
Ero1lb	T	A	13: 12,599,868 (GRCm38)	C240*	probably null	Het
Exog	A	G	9: 119,462,620 (GRCm38)	D297G	probably damaging	Het
Fbxl12	C	A	9: 20,638,864 (GRCm38)	R165L	possibly damaging	Het
Fer1l5	A	G	1: 36,417,774 (GRCm38)	Y1611C	possibly damaging	Het
Frmpd1	T	C	4: 45,285,034 (GRCm38)	V1285A	probably benign	Het
Gfpt1	G	C	6: 87,066,788 (GRCm38)		probably null	Het
Gm15446	T	C	5: 109,943,030 (GRCm38)	Y383H	possibly damaging	Het
Gsdmc	A	T	15: 63,777,340 (GRCm38)		probably null	Het
Hao1	A	G	2: 134,522,993 (GRCm38)	I238T	probably damaging	Het
Kcnq5	G	A	1: 21,479,424 (GRCm38)	R360C	probably damaging	Het
Kcnv2	T	A	19: 27,322,987 (GRCm38)	D79E	probably benign	Het
Lrrc8a	T	C	2: 30,255,545 (GRCm38)	Y124H	probably damaging	Het
Lrrc8d	T	A	5: 105,812,486 (GRCm38)	M254K	probably benign	Het
Map3k4	T	C	17: 12,232,934 (GRCm38)	N1489S	probably damaging	Het
Mapk8ip2	A	G	15: 89,455,219 (GRCm38)	D34G	probably damaging	Het
Myo9a	A	G	9: 59,860,140 (GRCm38)	T876A	probably damaging	Het
Pabpc2	C	T	18: 39,775,386 (GRCm38)	T568I	probably benign	Het
Pcdhga2	G	T	18: 37,669,168 (GRCm38)	A22S	probably benign	Het
Rc3h2	G	A	2: 37,382,799 (GRCm38)	T755I	probably benign	Het
Sertad4	A	G	1: 192,851,083 (GRCm38)	V15A	probably benign	Het
Slc28a2	A	G	2: 122,455,742 (GRCm38)	K520E	probably damaging	Het
Slc4a10	T	C	2: 62,296,796 (GRCm38)	V831A	possibly damaging	Het
Sorbs1	G	C	19: 40,376,800 (GRCm38)	R180G	probably benign	Het
Spag17	A	T	3: 100,124,185 (GRCm38)	I2255F	possibly damaging	Het
Sprn	C	T	7: 140,153,510 (GRCm38)		probably benign	Het
Stim1	T	C	7: 102,431,082 (GRCm38)		probably benign	Het
Stk24	C	A	14: 121,292,035 (GRCm38)	A402S	probably benign	Het
Sycp2	A	G	2: 178,374,533 (GRCm38)	L712P	probably damaging	Het
Tenm3	C	T	8: 48,342,633 (GRCm38)	G269S	probably damaging	Het
Zdbf2	A	G	1: 63,303,386 (GRCm38)	E308G	possibly damaging	Het
Zfp442	A	C	2: 150,409,042 (GRCm38)	H312Q	probably damaging	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	9,007,223 (GRCm38)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	9,009,951 (GRCm38)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	9,007,908 (GRCm38)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	9,004,307 (GRCm38)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	9,013,383 (GRCm38)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	9,013,730 (GRCm38)	nonsense	probably null
IGL00807:Ahnak	APN	19	9,008,522 (GRCm38)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	9,013,698 (GRCm38)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	9,012,887 (GRCm38)	intron	probably benign
IGL01118:Ahnak	APN	19	9,012,578 (GRCm38)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	9,002,494 (GRCm38)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	9,003,032 (GRCm38)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	9,011,703 (GRCm38)	missense	probably benign
IGL01541:Ahnak	APN	19	9,007,879 (GRCm38)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	9,002,839 (GRCm38)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	9,003,501 (GRCm38)	nonsense	probably null
IGL01746:Ahnak	APN	19	9,004,912 (GRCm38)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	9,000,118 (GRCm38)	missense	unknown
IGL01821:Ahnak	APN	19	9,012,118 (GRCm38)	missense	probably benign
IGL01913:Ahnak	APN	19	9,006,064 (GRCm38)	nonsense	probably null
IGL01934:Ahnak	APN	19	9,002,657 (GRCm38)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	9,006,557 (GRCm38)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	9,014,909 (GRCm38)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	9,002,855 (GRCm38)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	9,008,268 (GRCm38)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	9,005,987 (GRCm38)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	9,014,833 (GRCm38)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	9,004,016 (GRCm38)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	9,004,933 (GRCm38)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	9,003,308 (GRCm38)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	9,005,627 (GRCm38)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	9,012,077 (GRCm38)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	9,012,584 (GRCm38)	nonsense	probably null
IGL02717:Ahnak	APN	19	9,002,387 (GRCm38)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	9,009,707 (GRCm38)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	9,004,593 (GRCm38)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	9,002,596 (GRCm38)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	9,011,918 (GRCm38)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	9,006,508 (GRCm38)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	9,003,547 (GRCm38)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	9,005,212 (GRCm38)	intron	probably benign
IGL03176:Ahnak	APN	19	9,002,449 (GRCm38)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	9,008,166 (GRCm38)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	9,011,239 (GRCm38)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	9,009,325 (GRCm38)	intron	probably benign
IGL03371:Ahnak	APN	19	9,004,228 (GRCm38)	missense	possibly damaging	0.91
Eskimo	UTSW	19	9,009,574 (GRCm38)	missense	probably benign	0.31
Nanook	UTSW	19	9,003,231 (GRCm38)	missense	probably benign	0.42
Netsilik	UTSW	19	9,002,321 (GRCm38)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	9,002,387 (GRCm38)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	9,006,176 (GRCm38)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	9,012,056 (GRCm38)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	9,013,893 (GRCm38)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0141:Ahnak	UTSW	19	9,006,680 (GRCm38)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	9,005,725 (GRCm38)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	9,002,495 (GRCm38)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	9,008,350 (GRCm38)	nonsense	probably null
R0386:Ahnak	UTSW	19	9,011,144 (GRCm38)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	9,015,116 (GRCm38)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	9,012,871 (GRCm38)	intron	probably benign
R0463:Ahnak	UTSW	19	9,009,407 (GRCm38)	intron	probably benign
R0469:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0470:Ahnak	UTSW	19	9,008,967 (GRCm38)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	9,014,120 (GRCm38)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	9,007,151 (GRCm38)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	9,000,264 (GRCm38)	splice site	probably benign
R0506:Ahnak	UTSW	19	9,009,128 (GRCm38)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0557:Ahnak	UTSW	19	9,001,944 (GRCm38)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	9,013,698 (GRCm38)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	9,007,878 (GRCm38)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	9,013,402 (GRCm38)	nonsense	probably null
R0659:Ahnak	UTSW	19	9,015,002 (GRCm38)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	9,016,734 (GRCm38)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	9,016,734 (GRCm38)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	9,005,063 (GRCm38)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	9,006,433 (GRCm38)	nonsense	probably null
R0941:Ahnak	UTSW	19	9,009,914 (GRCm38)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	9,012,848 (GRCm38)	intron	probably benign
R1017:Ahnak	UTSW	19	9,010,543 (GRCm38)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	9,007,618 (GRCm38)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	9,013,125 (GRCm38)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	9,005,620 (GRCm38)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	9,004,245 (GRCm38)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	9,013,926 (GRCm38)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	9,015,619 (GRCm38)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	9,002,883 (GRCm38)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	9,004,169 (GRCm38)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	9,015,631 (GRCm38)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	9,007,082 (GRCm38)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	9,004,896 (GRCm38)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	9,004,896 (GRCm38)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	9,015,875 (GRCm38)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	9,015,875 (GRCm38)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	9,012,932 (GRCm38)	intron	probably benign
R1507:Ahnak	UTSW	19	9,010,077 (GRCm38)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	9,004,728 (GRCm38)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	9,002,375 (GRCm38)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	9,004,094 (GRCm38)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	9,008,987 (GRCm38)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	9,009,449 (GRCm38)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	9,009,963 (GRCm38)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	9,011,809 (GRCm38)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	9,010,655 (GRCm38)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	9,013,753 (GRCm38)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	9,002,438 (GRCm38)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	9,004,905 (GRCm38)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	9,005,867 (GRCm38)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	9,013,832 (GRCm38)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	9,002,048 (GRCm38)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	9,015,979 (GRCm38)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	9,007,088 (GRCm38)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	9,007,088 (GRCm38)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	9,017,881 (GRCm38)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	9,007,922 (GRCm38)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	9,015,083 (GRCm38)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	9,015,251 (GRCm38)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	9,007,075 (GRCm38)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	9,014,573 (GRCm38)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	9,013,181 (GRCm38)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	9,014,300 (GRCm38)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	9,007,056 (GRCm38)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	9,008,041 (GRCm38)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	9,011,557 (GRCm38)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	9,000,684 (GRCm38)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	9,011,494 (GRCm38)	nonsense	probably null
R2208:Ahnak	UTSW	19	9,017,732 (GRCm38)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	9,012,991 (GRCm38)	intron	probably benign
R2268:Ahnak	UTSW	19	9,010,574 (GRCm38)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	9,009,256 (GRCm38)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	9,002,851 (GRCm38)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	9,011,654 (GRCm38)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	9,011,654 (GRCm38)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	9,000,148 (GRCm38)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	9,009,944 (GRCm38)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	9,010,177 (GRCm38)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	9,006,752 (GRCm38)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	9,005,708 (GRCm38)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	9,006,958 (GRCm38)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	9,009,994 (GRCm38)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	9,007,898 (GRCm38)	missense	probably benign
R3723:Ahnak	UTSW	19	9,016,853 (GRCm38)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	9,009,023 (GRCm38)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	9,010,859 (GRCm38)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	9,010,859 (GRCm38)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	9,011,299 (GRCm38)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	9,014,327 (GRCm38)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	9,002,600 (GRCm38)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	9,000,786 (GRCm38)	nonsense	probably null
R4237:Ahnak	UTSW	19	9,001,783 (GRCm38)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	9,016,839 (GRCm38)	nonsense	probably null
R4331:Ahnak	UTSW	19	9,015,820 (GRCm38)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	9,012,083 (GRCm38)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	9,003,040 (GRCm38)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	9,014,930 (GRCm38)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	9,010,825 (GRCm38)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	9,003,724 (GRCm38)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	9,008,701 (GRCm38)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	9,004,855 (GRCm38)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	9,004,681 (GRCm38)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	9,012,258 (GRCm38)	intron	probably benign
R4704:Ahnak	UTSW	19	9,013,181 (GRCm38)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	9,016,906 (GRCm38)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	9,016,735 (GRCm38)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	9,007,301 (GRCm38)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	9,007,301 (GRCm38)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	9,011,975 (GRCm38)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	9,012,499 (GRCm38)	intron	probably benign
R4832:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R4882:Ahnak	UTSW	19	9,005,897 (GRCm38)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	9,012,754 (GRCm38)	intron	probably benign
R4895:Ahnak	UTSW	19	9,017,441 (GRCm38)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	9,010,967 (GRCm38)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	9,017,835 (GRCm38)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	9,015,100 (GRCm38)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	9,010,631 (GRCm38)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	9,012,458 (GRCm38)	intron	probably benign
R5073:Ahnak	UTSW	19	9,003,231 (GRCm38)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	9,014,759 (GRCm38)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	9,013,644 (GRCm38)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	9,017,087 (GRCm38)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	9,004,655 (GRCm38)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	9,010,904 (GRCm38)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	9,017,569 (GRCm38)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	9,015,665 (GRCm38)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	9,000,684 (GRCm38)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	9,015,341 (GRCm38)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	9,016,735 (GRCm38)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	9,003,691 (GRCm38)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	9,007,175 (GRCm38)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	9,006,917 (GRCm38)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	9,009,476 (GRCm38)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	9,013,094 (GRCm38)	nonsense	probably null
R5643:Ahnak	UTSW	19	9,010,657 (GRCm38)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	9,010,657 (GRCm38)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	9,014,615 (GRCm38)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	9,002,519 (GRCm38)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	9,001,840 (GRCm38)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	9,016,747 (GRCm38)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	9,010,253 (GRCm38)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	9,001,732 (GRCm38)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	9,013,562 (GRCm38)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	9,002,321 (GRCm38)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	9,015,248 (GRCm38)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	9,012,382 (GRCm38)	nonsense	probably null
R5808:Ahnak	UTSW	19	9,010,235 (GRCm38)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	9,010,052 (GRCm38)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	9,008,342 (GRCm38)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	9,018,211 (GRCm38)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	9,013,767 (GRCm38)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	9,011,903 (GRCm38)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	9,015,182 (GRCm38)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	9,016,585 (GRCm38)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	9,009,347 (GRCm38)	intron	probably benign
R6000:Ahnak	UTSW	19	9,013,111 (GRCm38)	nonsense	probably null
R6005:Ahnak	UTSW	19	9,015,161 (GRCm38)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	9,004,099 (GRCm38)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	9,004,099 (GRCm38)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	9,012,963 (GRCm38)	intron	probably benign
R6209:Ahnak	UTSW	19	9,012,566 (GRCm38)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	9,013,583 (GRCm38)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	9,008,025 (GRCm38)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	9,018,277 (GRCm38)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	9,015,003 (GRCm38)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	9,003,305 (GRCm38)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	9,006,626 (GRCm38)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	9,007,148 (GRCm38)	missense	probably benign	0.11
R6331:Ahnak	UTSW	19	9,006,625 (GRCm38)	missense	probably benign	0.18
R6355:Ahnak	UTSW	19	9,008,762 (GRCm38)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	9,009,574 (GRCm38)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	9,008,806 (GRCm38)	missense	probably benign	0.27
R6572:Ahnak	UTSW	19	9,007,976 (GRCm38)	missense	probably damaging	0.99
R6574:Ahnak	UTSW	19	9,017,047 (GRCm38)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	9,009,581 (GRCm38)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	9,015,310 (GRCm38)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	9,009,581 (GRCm38)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	9,011,562 (GRCm38)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	9,007,561 (GRCm38)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	9,011,857 (GRCm38)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	9,015,235 (GRCm38)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,037,168 (GRCm38)	nonsense	probably null
R6863:Ahnak	UTSW	19	9,012,365 (GRCm38)	intron	probably benign
R6876:Ahnak	UTSW	19	9,014,120 (GRCm38)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	9,015,215 (GRCm38)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	9,002,359 (GRCm38)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	9,013,488 (GRCm38)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	9,017,668 (GRCm38)	missense	probably damaging	1.00
R7202:Ahnak	UTSW	19	9,017,799 (GRCm38)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	9,012,488 (GRCm38)	missense	unknown
R7241:Ahnak	UTSW	19	9,009,031 (GRCm38)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	9,006,617 (GRCm38)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	9,002,143 (GRCm38)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	9,009,827 (GRCm38)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	9,001,792 (GRCm38)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	9,008,165 (GRCm38)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	9,003,205 (GRCm38)	missense	probably benign	0.02
R7400:Ahnak	UTSW	19	9,014,613 (GRCm38)	missense	probably damaging	0.99
R7444:Ahnak	UTSW	19	9,007,423 (GRCm38)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	9,004,822 (GRCm38)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	9,012,019 (GRCm38)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	9,002,351 (GRCm38)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	9,002,322 (GRCm38)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	9,006,824 (GRCm38)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	9,011,165 (GRCm38)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	9,016,156 (GRCm38)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	9,000,786 (GRCm38)	nonsense	probably null
R7583:Ahnak	UTSW	19	9,006,093 (GRCm38)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	9,004,574 (GRCm38)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	9,015,047 (GRCm38)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	9,009,315 (GRCm38)	missense	unknown
R7827:Ahnak	UTSW	19	9,005,344 (GRCm38)	nonsense	probably null
R7857:Ahnak	UTSW	19	9,007,468 (GRCm38)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	9,005,832 (GRCm38)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	9,014,084 (GRCm38)	nonsense	probably null
R7959:Ahnak	UTSW	19	9,010,649 (GRCm38)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	9,012,800 (GRCm38)	missense	unknown
R7979:Ahnak	UTSW	19	9,011,432 (GRCm38)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	9,012,083 (GRCm38)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	9,009,335 (GRCm38)	missense	unknown
R8033:Ahnak	UTSW	19	9,003,710 (GRCm38)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	9,007,123 (GRCm38)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	9,011,876 (GRCm38)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	9,000,100 (GRCm38)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	9,004,679 (GRCm38)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	9,002,255 (GRCm38)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	9,010,436 (GRCm38)	nonsense	probably null
R8241:Ahnak	UTSW	19	9,007,295 (GRCm38)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	9,001,946 (GRCm38)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	9,005,453 (GRCm38)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	9,009,662 (GRCm38)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	9,017,855 (GRCm38)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	9,008,749 (GRCm38)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	9,012,355 (GRCm38)	missense	unknown
R8549:Ahnak	UTSW	19	9,011,483 (GRCm38)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	9,005,996 (GRCm38)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	9,009,074 (GRCm38)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	9,013,346 (GRCm38)	nonsense	probably null
R8751:Ahnak	UTSW	19	9,010,145 (GRCm38)	missense	probably damaging	1.00
R8752:Ahnak	UTSW	19	9,015,537 (GRCm38)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	9,011,473 (GRCm38)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	9,006,890 (GRCm38)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	9,007,203 (GRCm38)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	9,000,742 (GRCm38)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	9,009,088 (GRCm38)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	9,011,735 (GRCm38)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	9,012,737 (GRCm38)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	9,004,113 (GRCm38)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	9,010,123 (GRCm38)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	9,007,253 (GRCm38)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	9,008,526 (GRCm38)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	9,010,347 (GRCm38)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	9,009,785 (GRCm38)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	9,014,923 (GRCm38)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	9,010,883 (GRCm38)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	9,012,579 (GRCm38)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	9,016,139 (GRCm38)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R9325:Ahnak	UTSW	19	9,013,893 (GRCm38)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R9340:Ahnak	UTSW	19	9,017,047 (GRCm38)	missense	probably benign	0.04
R9351:Ahnak	UTSW	19	9,007,868 (GRCm38)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	9,012,902 (GRCm38)	missense	unknown
R9462:Ahnak	UTSW	19	9,003,935 (GRCm38)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	9,010,861 (GRCm38)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	9,002,074 (GRCm38)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	9,010,094 (GRCm38)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,037,253 (GRCm38)	missense
R9534:Ahnak	UTSW	19	9,003,612 (GRCm38)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	9,003,785 (GRCm38)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	9,011,798 (GRCm38)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	9,012,482 (GRCm38)	missense	unknown
R9649:Ahnak	UTSW	19	9,008,422 (GRCm38)	nonsense	probably null
R9683:Ahnak	UTSW	19	9,007,355 (GRCm38)	missense	possibly damaging	0.94
R9691:Ahnak	UTSW	19	9,011,726 (GRCm38)	missense	possibly damaging	0.49
R9712:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9712:Ahnak	UTSW	19	9,007,028 (GRCm38)	small deletion	probably benign
R9713:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9715:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9725:Ahnak	UTSW	19	9,014,243 (GRCm38)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	9,004,169 (GRCm38)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	9,010,177 (GRCm38)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	9,013,619 (GRCm38)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	9,013,601 (GRCm38)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	9,013,619 (GRCm38)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	9,012,037 (GRCm38)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	9,016,082 (GRCm38)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	9,008,856 (GRCm38)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	9,017,468 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GTGGACTTGCATCTGAAAGGC -3'
(R):5'- CTTTGGGGCCTTTCAGATGC -3'

Sequencing Primer
(F):5'- ACATGGATGTGACAGTGCC -3'
(R):5'- TTTCAGATGCAAGTCCACATCAGG -3'

Posted On

2021-01-18