Incidental Mutation 'R8558:Sox6'
| ID |
660853 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sox6
|
| Ensembl Gene |
ENSMUSG00000051910 |
| Gene Name |
SRY (sex determining region Y)-box 6 |
| Synonyms |
|
| MMRRC Submission |
068521-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8558 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
115070107-115638031 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 115141033 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 482
(S482P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072583
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072804]
[ENSMUST00000106612]
[ENSMUST00000166207]
[ENSMUST00000166877]
[ENSMUST00000169129]
[ENSMUST00000205405]
[ENSMUST00000206034]
[ENSMUST00000206369]
|
| AlphaFold |
P40645 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072804
AA Change: S482P
PolyPhen 2
Score 0.119 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000072583
Gene: ENSMUSG00000051910
AA Change: S482P
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
184 |
261 |
N/A |
INTRINSIC |
|
low complexity region
|
462 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
507 |
517 |
N/A |
INTRINSIC |
|
HMG
|
619 |
689 |
1.5e-25 |
SMART |
|
low complexity region
|
797 |
809 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106612
AA Change: S440P
PolyPhen 2
Score 0.025 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000102223
Gene: ENSMUSG00000051910
AA Change: S440P
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
184 |
261 |
N/A |
INTRINSIC |
|
low complexity region
|
323 |
333 |
N/A |
INTRINSIC |
|
low complexity region
|
420 |
442 |
N/A |
INTRINSIC |
|
low complexity region
|
465 |
475 |
N/A |
INTRINSIC |
|
HMG
|
577 |
647 |
1.5e-25 |
SMART |
|
low complexity region
|
755 |
767 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166207
AA Change: S482P
PolyPhen 2
Score 0.119 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000129027
Gene: ENSMUSG00000051910
AA Change: S482P
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
184 |
261 |
N/A |
INTRINSIC |
|
low complexity region
|
462 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
507 |
517 |
N/A |
INTRINSIC |
|
HMG
|
619 |
689 |
1.5e-25 |
SMART |
|
low complexity region
|
797 |
809 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166877
AA Change: S442P
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000129512
Gene: ENSMUSG00000051910
AA Change: S442P
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
184 |
263 |
N/A |
INTRINSIC |
|
low complexity region
|
324 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
467 |
477 |
N/A |
INTRINSIC |
|
HMG
|
579 |
649 |
1.5e-25 |
SMART |
|
low complexity region
|
757 |
769 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000169129
AA Change: S442P
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000126404
Gene: ENSMUSG00000051910
AA Change: S442P
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
184 |
263 |
N/A |
INTRINSIC |
|
low complexity region
|
324 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
467 |
477 |
N/A |
INTRINSIC |
|
HMG
|
579 |
649 |
1.5e-25 |
SMART |
|
low complexity region
|
757 |
769 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205405
AA Change: S483P
PolyPhen 2
Score 0.416 (Sensitivity: 0.89; Specificity: 0.90)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000206034
AA Change: S441P
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206369
AA Change: S483P
PolyPhen 2
Score 0.416 (Sensitivity: 0.89; Specificity: 0.90)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of a family of transcriptional regulators containing high mobility group (HMG) DNA-binding domains. Function of the encoded protein is important for proper cardiac and skeletal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
PHENOTYPE: Homozygotes for null mutations exhibit cardioskeletal myopathy, cardiac blockage, delayed growth, and early postnatal lethality. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017N19Rik |
A |
T |
10: 100,430,497 (GRCm39) |
R51S |
probably benign |
Het |
| 1700067P10Rik |
G |
T |
17: 48,400,849 (GRCm39) |
E45* |
probably null |
Het |
| Abcb5 |
T |
C |
12: 118,841,566 (GRCm39) |
T960A |
probably benign |
Het |
| Abcc3 |
A |
G |
11: 94,242,623 (GRCm39) |
|
probably null |
Het |
| Adamtsl3 |
A |
T |
7: 82,077,600 (GRCm39) |
D95V |
possibly damaging |
Het |
| Ash1l |
T |
A |
3: 88,891,713 (GRCm39) |
S1197R |
probably damaging |
Het |
| BC034090 |
T |
A |
1: 155,097,085 (GRCm39) |
H671L |
possibly damaging |
Het |
| Bltp1 |
T |
A |
3: 37,102,750 (GRCm39) |
M1443K |
|
Het |
| Btnl9 |
T |
C |
11: 49,071,619 (GRCm39) |
E68G |
probably benign |
Het |
| C1qtnf1 |
A |
T |
11: 118,339,149 (GRCm39) |
Y273F |
probably damaging |
Het |
| C4b |
A |
T |
17: 34,955,541 (GRCm39) |
C714S |
probably damaging |
Het |
| Carmil1 |
G |
A |
13: 24,209,863 (GRCm39) |
T1204I |
probably benign |
Het |
| Cdk12 |
T |
C |
11: 98,101,915 (GRCm39) |
L591P |
unknown |
Het |
| Ces2f |
T |
A |
8: 105,679,758 (GRCm39) |
L417* |
probably null |
Het |
| Chl1 |
T |
A |
6: 103,685,390 (GRCm39) |
S810R |
probably benign |
Het |
| Ckap2 |
A |
G |
8: 22,658,811 (GRCm39) |
V644A |
possibly damaging |
Het |
| Ctdsp2 |
T |
A |
10: 126,829,746 (GRCm39) |
V126E |
probably damaging |
Het |
| Dok6 |
G |
T |
18: 89,492,066 (GRCm39) |
H170Q |
probably damaging |
Het |
| Dynlrb1 |
T |
C |
2: 155,084,728 (GRCm39) |
|
probably null |
Het |
| Eif5b |
T |
C |
1: 38,083,795 (GRCm39) |
L757S |
probably damaging |
Het |
| Epas1 |
A |
C |
17: 87,116,896 (GRCm39) |
T189P |
possibly damaging |
Het |
| Epha10 |
C |
A |
4: 124,788,777 (GRCm39) |
N283K |
|
Het |
| Epha5 |
C |
A |
5: 84,206,975 (GRCm39) |
G853C |
probably damaging |
Het |
| Gapvd1 |
A |
T |
2: 34,594,493 (GRCm39) |
H831Q |
probably damaging |
Het |
| Gcnt3 |
T |
A |
9: 69,941,996 (GRCm39) |
K191* |
probably null |
Het |
| Gm14226 |
T |
A |
2: 154,866,909 (GRCm39) |
S289T |
probably benign |
Het |
| Gm4846 |
T |
A |
1: 166,314,674 (GRCm39) |
D323V |
probably damaging |
Het |
| Golga3 |
G |
T |
5: 110,356,421 (GRCm39) |
R1036L |
possibly damaging |
Het |
| Gopc |
T |
C |
10: 52,229,580 (GRCm39) |
Q213R |
probably damaging |
Het |
| Hrh1 |
G |
A |
6: 114,457,564 (GRCm39) |
V282M |
probably benign |
Het |
| Ighv5-4 |
T |
C |
12: 113,561,078 (GRCm39) |
Y114C |
probably damaging |
Het |
| Igkv10-94 |
A |
T |
6: 68,681,636 (GRCm39) |
I68N |
probably damaging |
Het |
| Kcnj3 |
A |
G |
2: 55,336,875 (GRCm39) |
D247G |
possibly damaging |
Het |
| Lcn6 |
C |
A |
2: 25,570,718 (GRCm39) |
S102Y |
probably damaging |
Het |
| Matk |
C |
A |
10: 81,096,765 (GRCm39) |
H232N |
probably benign |
Het |
| Mcm9 |
C |
T |
10: 53,492,068 (GRCm39) |
V366I |
probably benign |
Het |
| Nadk |
A |
G |
4: 155,669,844 (GRCm39) |
I176V |
probably benign |
Het |
| Nlrp12 |
A |
G |
7: 3,298,111 (GRCm39) |
L20P |
probably damaging |
Het |
| Oga |
T |
C |
19: 45,746,511 (GRCm39) |
S763G |
probably benign |
Het |
| Or10ag56 |
A |
T |
2: 87,139,583 (GRCm39) |
Q170L |
probably benign |
Het |
| Or1e21 |
G |
A |
11: 73,344,309 (GRCm39) |
S243F |
probably damaging |
Het |
| Or4a72 |
A |
G |
2: 89,405,329 (GRCm39) |
L247P |
probably damaging |
Het |
| Pcdhgb6 |
T |
A |
18: 37,877,237 (GRCm39) |
D648E |
probably damaging |
Het |
| Pkd1l3 |
A |
T |
8: 110,362,012 (GRCm39) |
N1018I |
probably damaging |
Het |
| Plch2 |
T |
C |
4: 155,083,391 (GRCm39) |
K516E |
probably damaging |
Het |
| Pmpca |
G |
C |
2: 26,285,046 (GRCm39) |
E424Q |
possibly damaging |
Het |
| Pnma2 |
C |
T |
14: 67,153,972 (GRCm39) |
A132V |
probably benign |
Het |
| Prkn |
T |
C |
17: 11,456,472 (GRCm39) |
S99P |
probably benign |
Het |
| Prune2 |
A |
G |
19: 17,099,602 (GRCm39) |
E1702G |
probably damaging |
Het |
| Qars1 |
T |
A |
9: 108,392,422 (GRCm39) |
H756Q |
probably benign |
Het |
| Rab5a |
A |
G |
17: 53,790,877 (GRCm39) |
|
probably benign |
Het |
| Rars2 |
A |
G |
4: 34,657,199 (GRCm39) |
D515G |
probably damaging |
Het |
| Rpe65 |
T |
A |
3: 159,320,429 (GRCm39) |
C329S |
probably damaging |
Het |
| Rps6ka2 |
G |
A |
17: 7,523,316 (GRCm39) |
V231M |
possibly damaging |
Het |
| Rsf1 |
GCG |
GCGACGGCGCCG |
7: 97,229,114 (GRCm39) |
|
probably benign |
Het |
| Scrt1 |
G |
T |
15: 76,403,843 (GRCm39) |
S49* |
probably null |
Het |
| Sec23b |
C |
G |
2: 144,428,308 (GRCm39) |
D640E |
possibly damaging |
Het |
| Setdb1 |
C |
T |
3: 95,261,979 (GRCm39) |
V96M |
possibly damaging |
Het |
| Sik3 |
C |
A |
9: 46,066,746 (GRCm39) |
A175E |
probably damaging |
Het |
| Smarcad1 |
A |
G |
6: 65,060,908 (GRCm39) |
K463E |
probably benign |
Het |
| Sobp |
A |
C |
10: 43,003,888 (GRCm39) |
C154G |
probably damaging |
Het |
| Spen |
C |
T |
4: 141,197,681 (GRCm39) |
A3396T |
probably benign |
Het |
| Spink11 |
T |
A |
18: 44,324,748 (GRCm39) |
R75* |
probably null |
Het |
| Sptb |
T |
C |
12: 76,659,561 (GRCm39) |
H1113R |
probably benign |
Het |
| Sypl2 |
A |
T |
3: 108,125,004 (GRCm39) |
V119E |
probably damaging |
Het |
| Tbc1d24 |
T |
C |
17: 24,427,903 (GRCm39) |
S20G |
unknown |
Het |
| Tektl1 |
T |
C |
10: 78,583,035 (GRCm39) |
K450E |
probably damaging |
Het |
| Top2a |
A |
T |
11: 98,912,549 (GRCm39) |
V106D |
probably damaging |
Het |
| Tspyl4 |
G |
C |
10: 34,174,261 (GRCm39) |
R251P |
probably damaging |
Het |
| Ttc21a |
T |
A |
9: 119,787,835 (GRCm39) |
L801Q |
probably damaging |
Het |
| Vgll3 |
A |
G |
16: 65,624,844 (GRCm39) |
E64G |
probably damaging |
Het |
| Vmn2r30 |
A |
G |
7: 7,315,655 (GRCm39) |
I726T |
possibly damaging |
Het |
| Vmn2r81 |
T |
C |
10: 79,106,467 (GRCm39) |
S482P |
possibly damaging |
Het |
| Wasf1 |
T |
G |
10: 40,806,648 (GRCm39) |
M97R |
possibly damaging |
Het |
| Wdr33 |
T |
A |
18: 31,962,947 (GRCm39) |
M98K |
probably benign |
Het |
| Wdr73 |
G |
A |
7: 80,548,254 (GRCm39) |
T95I |
probably damaging |
Het |
|
| Other mutations in Sox6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00518:Sox6
|
APN |
7 |
115,076,441 (GRCm39) |
missense |
probably benign |
|
|
IGL00957:Sox6
|
APN |
7 |
115,376,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01624:Sox6
|
APN |
7 |
115,076,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02057:Sox6
|
APN |
7 |
115,149,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02385:Sox6
|
APN |
7 |
115,149,274 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02410:Sox6
|
APN |
7 |
115,085,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02736:Sox6
|
APN |
7 |
115,179,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02747:Sox6
|
APN |
7 |
115,088,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02792:Sox6
|
APN |
7 |
115,140,884 (GRCm39) |
missense |
probably benign |
|
|
PIT4480001:Sox6
|
UTSW |
7 |
115,196,744 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0458:Sox6
|
UTSW |
7 |
115,089,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0689:Sox6
|
UTSW |
7 |
115,085,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0800:Sox6
|
UTSW |
7 |
115,178,249 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1220:Sox6
|
UTSW |
7 |
115,261,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1474:Sox6
|
UTSW |
7 |
115,300,926 (GRCm39) |
splice site |
probably benign |
|
|
R1547:Sox6
|
UTSW |
7 |
115,300,957 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1570:Sox6
|
UTSW |
7 |
115,376,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1674:Sox6
|
UTSW |
7 |
115,400,654 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1704:Sox6
|
UTSW |
7 |
115,076,183 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1754:Sox6
|
UTSW |
7 |
115,076,290 (GRCm39) |
missense |
probably benign |
|
|
R1833:Sox6
|
UTSW |
7 |
115,376,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1868:Sox6
|
UTSW |
7 |
115,258,773 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1893:Sox6
|
UTSW |
7 |
115,143,803 (GRCm39) |
missense |
probably benign |
0.28 |
|
R2386:Sox6
|
UTSW |
7 |
115,196,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2431:Sox6
|
UTSW |
7 |
115,149,242 (GRCm39) |
splice site |
probably null |
|
|
R4303:Sox6
|
UTSW |
7 |
115,143,704 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4319:Sox6
|
UTSW |
7 |
115,179,798 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4320:Sox6
|
UTSW |
7 |
115,179,798 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4321:Sox6
|
UTSW |
7 |
115,179,798 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4323:Sox6
|
UTSW |
7 |
115,179,798 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4335:Sox6
|
UTSW |
7 |
115,111,959 (GRCm39) |
missense |
probably benign |
|
|
R4567:Sox6
|
UTSW |
7 |
115,261,557 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4776:Sox6
|
UTSW |
7 |
115,140,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Sox6
|
UTSW |
7 |
115,085,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4914:Sox6
|
UTSW |
7 |
115,076,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Sox6
|
UTSW |
7 |
115,076,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5184:Sox6
|
UTSW |
7 |
115,376,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5372:Sox6
|
UTSW |
7 |
115,149,386 (GRCm39) |
nonsense |
probably null |
|
|
R5454:Sox6
|
UTSW |
7 |
115,301,008 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5663:Sox6
|
UTSW |
7 |
115,149,289 (GRCm39) |
missense |
probably benign |
|
|
R5685:Sox6
|
UTSW |
7 |
115,178,392 (GRCm39) |
splice site |
probably null |
|
|
R5734:Sox6
|
UTSW |
7 |
115,140,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6020:Sox6
|
UTSW |
7 |
115,085,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6211:Sox6
|
UTSW |
7 |
115,400,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6263:Sox6
|
UTSW |
7 |
115,076,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6549:Sox6
|
UTSW |
7 |
115,085,927 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6576:Sox6
|
UTSW |
7 |
115,300,937 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6680:Sox6
|
UTSW |
7 |
115,076,218 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6709:Sox6
|
UTSW |
7 |
115,301,024 (GRCm39) |
splice site |
probably null |
|
|
R6747:Sox6
|
UTSW |
7 |
115,140,966 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6755:Sox6
|
UTSW |
7 |
115,261,677 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Sox6
|
UTSW |
7 |
115,089,044 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7423:Sox6
|
UTSW |
7 |
115,149,258 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7455:Sox6
|
UTSW |
7 |
115,088,904 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7522:Sox6
|
UTSW |
7 |
115,400,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Sox6
|
UTSW |
7 |
115,376,408 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7852:Sox6
|
UTSW |
7 |
115,400,839 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R7936:Sox6
|
UTSW |
7 |
115,143,830 (GRCm39) |
missense |
probably benign |
|
|
R8278:Sox6
|
UTSW |
7 |
115,076,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Sox6
|
UTSW |
7 |
115,300,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8682:Sox6
|
UTSW |
7 |
115,076,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8693:Sox6
|
UTSW |
7 |
115,261,632 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8712:Sox6
|
UTSW |
7 |
115,196,743 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8972:Sox6
|
UTSW |
7 |
115,076,218 (GRCm39) |
nonsense |
probably null |
|
|
R9297:Sox6
|
UTSW |
7 |
115,261,557 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9318:Sox6
|
UTSW |
7 |
115,261,557 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9517:Sox6
|
UTSW |
7 |
115,111,970 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9688:Sox6
|
UTSW |
7 |
115,076,225 (GRCm39) |
missense |
probably benign |
|
|
X0061:Sox6
|
UTSW |
7 |
115,076,383 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0065:Sox6
|
UTSW |
7 |
115,149,343 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACAGGATTACCTTCTCAGTCCTG -3'
(R):5'- GGGTATCCTCCATGTGCAAC -3'
Sequencing Primer
(F):5'- AGTCCTGCAGTTGCTCAGC -3'
(R):5'- AACCTGTACAGCTTGGTTGAC -3'
|
| Posted On |
2021-03-08 |
Incidental Mutation