Mutagenetix > Incidental Mutation

Incidental Mutation 'R8669:Naip2'

661068

Institutional Source

Beutler Lab

Gene Symbol

Naip2

Ensembl Gene

ENSMUSG00000078945

Gene Name

NLR family, apoptosis inhibitory protein 2

Synonyms

Naip-rs6, Birc1b, Naip2

MMRRC Submission

068524-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

R8669 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

100280571-100338600 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 100325477 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Glycine at position 144 (S144G)

Ref Sequence

ENSEMBL: ENSMUSP00000070827 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000067975] [ENSMUST00000117913] [ENSMUST00000167986]

AlphaFold

Q9QUK4

Predicted Effect

probably benign
Transcript: ENSMUST00000067975
AA Change: S144G

PolyPhen 2 Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000070827
Gene: ENSMUSG00000078945
AA Change: S144G

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	1.9e-36	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000117913
AA Change: S144G

PolyPhen 2 Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000113890
Gene: ENSMUSG00000078945
AA Change: S144G

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	1.9e-36	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000167986
AA Change: S144G

PolyPhen 2 Score 0.135 (Sensitivity: 0.92; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000125852
Gene: ENSMUSG00000078945
AA Change: S144G

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	8.6e-35	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.7%

Validation Efficiency

98% (53/54)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930447C04Rik	A	T	12: 72,949,234 (GRCm39)	S305T	probably benign	Het
Ankrd42	A	G	7: 92,268,881 (GRCm39)	V154A	possibly damaging	Het
Apc2	C	T	10: 80,149,491 (GRCm39)	T1515I	probably damaging	Het
Blzf1	T	A	1: 164,130,113 (GRCm39)	N80Y	possibly damaging	Het
Cacna2d1	T	C	5: 16,140,013 (GRCm39)	M1T	probably null	Het
Ccdc125	T	C	13: 100,832,683 (GRCm39)	L420P	probably damaging	Het
Ccdc162	T	C	10: 41,428,352 (GRCm39)	T1976A	probably benign	Het
Cdc20b	C	T	13: 113,208,460 (GRCm39)	P219S	possibly damaging	Het
Cep89	A	G	7: 35,128,602 (GRCm39)	D585G	probably benign	Het
Crnn	A	T	3: 93,056,296 (GRCm39)	R361*	probably null	Het
Defb5	A	G	8: 19,300,761 (GRCm39)	I38V	probably benign	Het
Defb8	A	G	8: 19,495,973 (GRCm39)	V29A	probably benign	Het
Dgkh	A	G	14: 78,962,459 (GRCm39)	V24A	probably benign	Het
Dhrs13	G	C	11: 77,923,492 (GRCm39)	R70P	possibly damaging	Het
Dnah12	A	T	14: 26,552,582 (GRCm39)		probably benign	Het
Dsg2	A	G	18: 20,723,132 (GRCm39)	N386S	probably damaging	Het
Dyrk1a	G	T	16: 94,464,650 (GRCm39)	R77L	probably damaging	Het
Fbxw19	G	T	9: 109,313,482 (GRCm39)	L239I	probably benign	Het
Gal3st2b	A	T	1: 93,868,764 (GRCm39)	I332L	possibly damaging	Het
Gcnt1	T	G	19: 17,307,143 (GRCm39)	K194T	probably benign	Het
Gm7298	T	C	6: 121,742,002 (GRCm39)	W475R	probably benign	Het
Gpatch1	C	A	7: 34,991,204 (GRCm39)	W613C	probably damaging	Het
Gulp1	T	A	1: 44,805,270 (GRCm39)	S120T	probably benign	Het
Ift122	C	A	6: 115,900,252 (GRCm39)	Q946K	probably damaging	Het
Itpr1	T	A	6: 108,370,928 (GRCm39)	L1065H	probably damaging	Het
Kcnq5	T	C	1: 21,476,050 (GRCm39)	D579G	probably damaging	Het
Klhl40	T	A	9: 121,607,088 (GRCm39)	S83T	probably benign	Het
Krt19	T	C	11: 100,031,993 (GRCm39)	K320E	probably damaging	Het
Krt87	C	A	15: 101,385,777 (GRCm39)	V273L	probably benign	Het
Lgals4	C	T	7: 28,540,921 (GRCm39)	R282C	probably damaging	Het
Lrp1b	A	G	2: 41,172,047 (GRCm39)		probably null	Het
Lrrk1	G	A	7: 65,912,344 (GRCm39)	L1739F	probably benign	Het
Mthfr	A	G	4: 148,135,934 (GRCm39)	N336D	probably benign	Het
Myo6	T	G	9: 80,173,531 (GRCm39)	L557R	unknown	Het
Nfatc1	T	C	18: 80,725,406 (GRCm39)	K453E	probably damaging	Het
Or52ab7	A	T	7: 102,978,281 (GRCm39)	D196V	probably benign	Het
Osm	A	T	11: 4,189,665 (GRCm39)	I150L	probably benign	Het
Phtf1	T	A	3: 103,910,792 (GRCm39)	N639K	probably benign	Het
Prpf40b	T	A	15: 99,201,228 (GRCm39)	M1K	probably null	Het
Rhbdl3	G	A	11: 80,244,339 (GRCm39)	V349M	probably damaging	Het
Senp7	T	C	16: 55,986,315 (GRCm39)	S582P	probably damaging	Het
Slc16a14	A	G	1: 84,900,605 (GRCm39)	S127P	probably benign	Het
Slc22a21	C	T	11: 53,870,643 (GRCm39)	W14*	probably null	Het
Slc6a18	T	A	13: 73,812,430 (GRCm39)	E553D	probably benign	Het
Speer4a1	T	G	5: 26,243,236 (GRCm39)	N83T	probably damaging	Het
Svep1	T	A	4: 58,070,119 (GRCm39)	S2556C	possibly damaging	Het
Tc2n	T	C	12: 101,660,851 (GRCm39)	N127S	probably damaging	Het
Tcstv7b	C	A	13: 120,702,338 (GRCm39)	P45T	probably benign	Het
Tenm4	C	T	7: 96,555,148 (GRCm39)	P2618S	probably benign	Het
Thra	T	C	11: 98,654,476 (GRCm39)	V282A	possibly damaging	Het
Tmem161b	A	T	13: 84,420,288 (GRCm39)		probably null	Het
Tmem218	C	T	9: 37,133,815 (GRCm39)	A85V	probably benign	Het
Txnip	T	C	3: 96,466,252 (GRCm39)	Y100H	probably damaging	Het
Unc5c	A	G	3: 141,509,704 (GRCm39)	D728G	possibly damaging	Het
Zfp462	T	A	4: 55,051,313 (GRCm39)	I2262K	probably damaging	Het
Zfp804a	A	T	2: 82,088,106 (GRCm39)	D645V	probably damaging	Het

Other mutations in Naip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00515:Naip2	APN	13	100,291,395 (GRCm39)	missense	probably benign	0.00
IGL00676:Naip2	APN	13	100,289,140 (GRCm39)	missense	probably damaging	1.00
IGL00870:Naip2	APN	13	100,288,568 (GRCm39)	splice site	probably benign
IGL00908:Naip2	APN	13	100,297,157 (GRCm39)	missense	probably benign	0.01
IGL00916:Naip2	APN	13	100,297,939 (GRCm39)	missense	probably damaging	0.97
IGL00949:Naip2	APN	13	100,298,099 (GRCm39)	missense	probably damaging	1.00
IGL01010:Naip2	APN	13	100,291,446 (GRCm39)	missense	probably damaging	0.99
IGL01642:Naip2	APN	13	100,297,445 (GRCm39)	missense	probably damaging	0.97
IGL01884:Naip2	APN	13	100,325,329 (GRCm39)	splice site	probably benign
IGL01917:Naip2	APN	13	100,298,591 (GRCm39)	missense	probably benign	0.00
IGL02015:Naip2	APN	13	100,298,115 (GRCm39)	missense	possibly damaging	0.57
IGL02315:Naip2	APN	13	100,297,744 (GRCm39)	missense	probably damaging	1.00
IGL02328:Naip2	APN	13	100,297,877 (GRCm39)	missense	probably damaging	1.00
IGL02735:Naip2	APN	13	100,296,722 (GRCm39)	missense	probably damaging	0.99
IGL02738:Naip2	APN	13	100,325,685 (GRCm39)	missense	probably benign	0.01
IGL02887:Naip2	APN	13	100,298,020 (GRCm39)	missense	possibly damaging	0.90
IGL02894:Naip2	APN	13	100,320,297 (GRCm39)	missense	probably benign
IGL02894:Naip2	APN	13	100,297,505 (GRCm39)	missense	probably damaging	1.00
IGL02974:Naip2	APN	13	100,298,186 (GRCm39)	missense	probably damaging	1.00
IGL03024:Naip2	APN	13	100,325,862 (GRCm39)	missense	possibly damaging	0.50
IGL03056:Naip2	APN	13	100,298,795 (GRCm39)	missense	possibly damaging	0.90
IGL03281:Naip2	APN	13	100,298,128 (GRCm39)	missense	probably damaging	0.99
R0131:Naip2	UTSW	13	100,320,296 (GRCm39)	missense	probably benign	0.01
R0131:Naip2	UTSW	13	100,320,296 (GRCm39)	missense	probably benign	0.01
R0132:Naip2	UTSW	13	100,320,296 (GRCm39)	missense	probably benign	0.01
R0310:Naip2	UTSW	13	100,285,350 (GRCm39)	missense	probably damaging	1.00
R0367:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0368:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0422:Naip2	UTSW	13	100,297,621 (GRCm39)	missense	probably benign	0.10
R0441:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0445:Naip2	UTSW	13	100,298,395 (GRCm39)	missense	possibly damaging	0.91
R0446:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0464:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0466:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0467:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0486:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0533:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R0853:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R0853:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R0855:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R0855:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R0904:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R0904:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R0906:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R0906:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R0908:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R0908:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R0959:Naip2	UTSW	13	100,291,419 (GRCm39)	missense	probably benign	0.03
R0959:Naip2	UTSW	13	100,291,386 (GRCm39)	missense	probably benign	0.01
R0962:Naip2	UTSW	13	100,315,893 (GRCm39)	missense	probably damaging	1.00
R1024:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1024:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R1186:Naip2	UTSW	13	100,298,545 (GRCm39)	frame shift	probably null
R1186:Naip2	UTSW	13	100,298,489 (GRCm39)	missense	possibly damaging	0.63
R1217:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1217:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R1340:Naip2	UTSW	13	100,325,630 (GRCm39)	missense	possibly damaging	0.80
R1342:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1342:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R1404:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R1423:Naip2	UTSW	13	100,291,380 (GRCm39)	missense	possibly damaging	0.59
R1423:Naip2	UTSW	13	100,291,355 (GRCm39)	intron	probably benign
R1423:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1423:Naip2	UTSW	13	100,291,386 (GRCm39)	missense	probably benign	0.01
R1426:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1426:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R1472:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1575:Naip2	UTSW	13	100,291,537 (GRCm39)	intron	probably benign
R1575:Naip2	UTSW	13	100,291,529 (GRCm39)	missense	probably benign	0.00
R1576:Naip2	UTSW	13	100,291,529 (GRCm39)	missense	probably benign	0.00
R1576:Naip2	UTSW	13	100,291,537 (GRCm39)	intron	probably benign
R1599:Naip2	UTSW	13	100,298,489 (GRCm39)	missense	possibly damaging	0.63
R1640:Naip2	UTSW	13	100,298,489 (GRCm39)	missense	possibly damaging	0.63
R1641:Naip2	UTSW	13	100,298,489 (GRCm39)	missense	possibly damaging	0.63
R1642:Naip2	UTSW	13	100,298,489 (GRCm39)	missense	possibly damaging	0.63
R1643:Naip2	UTSW	13	100,298,489 (GRCm39)	missense	possibly damaging	0.63
R1644:Naip2	UTSW	13	100,319,437 (GRCm39)	missense	possibly damaging	0.83
R1681:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1681:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R1891:Naip2	UTSW	13	100,291,395 (GRCm39)	missense	probably benign	0.00
R1913:Naip2	UTSW	13	100,288,665 (GRCm39)	critical splice acceptor site	probably null
R1937:Naip2	UTSW	13	100,298,368 (GRCm39)	missense	probably benign	0.00
R1937:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign
R1993:Naip2	UTSW	13	100,298,515 (GRCm39)	missense	probably benign	0.03
R2001:Naip2	UTSW	13	100,281,096 (GRCm39)	missense	probably damaging	1.00
R2055:Naip2	UTSW	13	100,315,880 (GRCm39)	missense	probably benign	0.07
R2198:Naip2	UTSW	13	100,289,100 (GRCm39)	missense	probably damaging	1.00
R2906:Naip2	UTSW	13	100,298,504 (GRCm39)	missense	probably damaging	1.00
R2931:Naip2	UTSW	13	100,291,529 (GRCm39)	missense	probably benign	0.00
R3014:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R3016:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R3037:Naip2	UTSW	13	100,291,457 (GRCm39)	missense	probably benign	0.08
R3414:Naip2	UTSW	13	100,325,771 (GRCm39)	nonsense	probably null
R3437:Naip2	UTSW	13	100,291,419 (GRCm39)	missense	probably benign	0.03
R3713:Naip2	UTSW	13	100,298,410 (GRCm39)	missense	probably damaging	1.00
R3806:Naip2	UTSW	13	100,289,142 (GRCm39)	missense	possibly damaging	0.92
R3847:Naip2	UTSW	13	100,315,940 (GRCm39)	missense	probably damaging	1.00
R3847:Naip2	UTSW	13	100,315,941 (GRCm39)	missense	probably damaging	1.00
R3848:Naip2	UTSW	13	100,315,940 (GRCm39)	missense	probably damaging	1.00
R3848:Naip2	UTSW	13	100,315,941 (GRCm39)	missense	probably damaging	1.00
R3849:Naip2	UTSW	13	100,315,940 (GRCm39)	missense	probably damaging	1.00
R3849:Naip2	UTSW	13	100,315,941 (GRCm39)	missense	probably damaging	1.00
R3850:Naip2	UTSW	13	100,315,940 (GRCm39)	missense	probably damaging	1.00
R3850:Naip2	UTSW	13	100,315,941 (GRCm39)	missense	probably damaging	1.00
R3891:Naip2	UTSW	13	100,297,606 (GRCm39)	missense	probably damaging	0.99
R4419:Naip2	UTSW	13	100,297,133 (GRCm39)	missense	probably benign	0.03
R4456:Naip2	UTSW	13	100,291,419 (GRCm39)	missense	probably benign	0.03
R4458:Naip2	UTSW	13	100,291,419 (GRCm39)	missense	probably benign	0.03
R4689:Naip2	UTSW	13	100,285,320 (GRCm39)	missense	probably damaging	1.00
R4797:Naip2	UTSW	13	100,298,243 (GRCm39)	missense	probably damaging	1.00
R4852:Naip2	UTSW	13	100,298,044 (GRCm39)	missense	probably benign
R4922:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R5135:Naip2	UTSW	13	100,315,948 (GRCm39)	missense	probably damaging	0.98
R5185:Naip2	UTSW	13	100,325,859 (GRCm39)	missense	probably damaging	1.00
R5265:Naip2	UTSW	13	100,289,068 (GRCm39)	missense	probably damaging	1.00
R5451:Naip2	UTSW	13	100,325,368 (GRCm39)	missense	probably benign	0.12
R5521:Naip2	UTSW	13	100,291,422 (GRCm39)	missense	probably damaging	1.00
R5737:Naip2	UTSW	13	100,298,362 (GRCm39)	missense	probably benign	0.38
R6244:Naip2	UTSW	13	100,288,645 (GRCm39)	missense	probably damaging	1.00
R6478:Naip2	UTSW	13	100,298,549 (GRCm39)	missense	probably benign
R6480:Naip2	UTSW	13	100,298,549 (GRCm39)	missense	probably benign
R6481:Naip2	UTSW	13	100,298,549 (GRCm39)	missense	probably benign
R6490:Naip2	UTSW	13	100,297,193 (GRCm39)	missense	probably benign
R6653:Naip2	UTSW	13	100,288,644 (GRCm39)	missense	probably benign	0.00
R6653:Naip2	UTSW	13	100,298,352 (GRCm39)	missense	probably benign
R6768:Naip2	UTSW	13	100,314,832 (GRCm39)	nonsense	probably null
R6791:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R6793:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R6890:Naip2	UTSW	13	100,298,549 (GRCm39)	missense	probably benign
R7036:Naip2	UTSW	13	100,291,529 (GRCm39)	missense	probably benign	0.00
R7213:Naip2	UTSW	13	100,323,991 (GRCm39)	missense	probably damaging	1.00
R7342:Naip2	UTSW	13	100,325,864 (GRCm39)	missense	probably benign	0.09
R7445:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R7572:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R7699:Naip2	UTSW	13	100,296,877 (GRCm39)	missense	probably benign	0.00
R7840:Naip2	UTSW	13	100,280,917 (GRCm39)	missense	probably benign	0.14
R7874:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R7874:Naip2	UTSW	13	100,291,459 (GRCm39)	missense	probably benign	0.00
R8038:Naip2	UTSW	13	100,298,570 (GRCm39)	missense	probably benign	0.00
R8065:Naip2	UTSW	13	100,325,730 (GRCm39)	missense	probably damaging	1.00
R8094:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R8166:Naip2	UTSW	13	100,298,515 (GRCm39)	missense	probably benign	0.03
R8378:Naip2	UTSW	13	100,298,290 (GRCm39)	missense	probably benign	0.01
R8691:Naip2	UTSW	13	100,297,676 (GRCm39)	missense	probably damaging	1.00
R8716:Naip2	UTSW	13	100,280,914 (GRCm39)	missense	probably benign
R8720:Naip2	UTSW	13	100,298,630 (GRCm39)	missense	probably benign	0.04
R8888:Naip2	UTSW	13	100,325,644 (GRCm39)	missense	probably benign	0.01
R8895:Naip2	UTSW	13	100,325,644 (GRCm39)	missense	probably benign	0.01
R9031:Naip2	UTSW	13	100,314,776 (GRCm39)	missense	possibly damaging	0.55
R9072:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R9072:Naip2	UTSW	13	100,291,459 (GRCm39)	missense	probably benign	0.00
R9074:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R9074:Naip2	UTSW	13	100,291,459 (GRCm39)	missense	probably benign	0.00
R9077:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
R9077:Naip2	UTSW	13	100,291,459 (GRCm39)	missense	probably benign	0.00
R9176:Naip2	UTSW	13	100,298,707 (GRCm39)	missense	probably damaging	1.00
R9219:Naip2	UTSW	13	100,297,213 (GRCm39)	missense	probably benign	0.06
R9358:Naip2	UTSW	13	100,298,080 (GRCm39)	missense	probably damaging	1.00
R9371:Naip2	UTSW	13	100,298,354 (GRCm39)	nonsense	probably null
R9414:Naip2	UTSW	13	100,298,243 (GRCm39)	missense	probably damaging	1.00
R9415:Naip2	UTSW	13	100,298,243 (GRCm39)	missense	probably damaging	1.00
R9416:Naip2	UTSW	13	100,298,243 (GRCm39)	missense	probably damaging	1.00
R9708:Naip2	UTSW	13	100,298,087 (GRCm39)	missense	probably damaging	0.99
V5622:Naip2	UTSW	13	100,291,537 (GRCm39)	intron	probably benign
V5622:Naip2	UTSW	13	100,291,529 (GRCm39)	missense	probably benign	0.00
V5622:Naip2	UTSW	13	100,291,529 (GRCm39)	missense	probably benign	0.00
X0063:Naip2	UTSW	13	100,298,266 (GRCm39)	missense	probably damaging	1.00
Y5405:Naip2	UTSW	13	100,291,468 (GRCm39)	missense	probably benign
Z1088:Naip2	UTSW	13	100,298,417 (GRCm39)	missense	probably benign
Z1176:Naip2	UTSW	13	100,298,417 (GRCm39)	missense	probably benign
Z1176:Naip2	UTSW	13	100,298,101 (GRCm39)	missense	probably benign	0.02
Z1177:Naip2	UTSW	13	100,298,417 (GRCm39)	missense	probably benign
Z1177:Naip2	UTSW	13	100,289,137 (GRCm39)	missense	possibly damaging	0.65
Z1177:Naip2	UTSW	13	100,299,373 (GRCm39)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- GCTACACTAGAAGTCAATTAAAGTTGG -3'
(R):5'- TGGGTTTTACCACACAGGGG -3'

Sequencing Primer
(F):5'- CAACCACTGTTTCAGGAGATCTG -3'
(R):5'- ACAGGGGTGAAACTTGGGGTTC -3'

Posted On

2021-03-08