Incidental Mutation 'R8679:Tnrc6c'
| ID |
661615 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6c
|
| Ensembl Gene |
ENSMUSG00000025571 |
| Gene Name |
trinucleotide repeat containing 6C |
| Synonyms |
9930033H14Rik |
| MMRRC Submission |
068534-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8679 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
117545115-117654265 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 117604961 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 32
(L32P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000026658
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026658]
[ENSMUST00000106344]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026658
AA Change: L32P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000026658
Gene: ENSMUSG00000025571
AA Change: L32P
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106344
AA Change: L32P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000101951
Gene: ENSMUSG00000025571
AA Change: L32P
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.4%
|
| Validation Efficiency |
98% (91/93) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap allele exhibit complete neonatal lethality with cyanosis, respiratory distress and thickened mesenchyme in air sacs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc5 |
T |
C |
16: 20,152,479 (GRCm39) |
T1356A |
possibly damaging |
Het |
| Ace3 |
A |
G |
11: 105,886,701 (GRCm39) |
T154A |
probably benign |
Het |
| Arhgap31 |
C |
A |
16: 38,422,966 (GRCm39) |
Q1033H |
probably damaging |
Het |
| C1qtnf1 |
C |
T |
11: 118,337,340 (GRCm39) |
R57* |
probably null |
Het |
| Cacna1g |
T |
C |
11: 94,319,962 (GRCm39) |
T1405A |
probably damaging |
Het |
| Cacna1i |
A |
G |
15: 80,260,011 (GRCm39) |
|
probably benign |
Het |
| Cdca4 |
T |
A |
12: 112,785,734 (GRCm39) |
|
probably null |
Het |
| Cpa4 |
T |
A |
6: 30,585,158 (GRCm39) |
M314K |
probably damaging |
Het |
| Cpn2 |
A |
T |
16: 30,078,085 (GRCm39) |
S539T |
possibly damaging |
Het |
| Crebbp |
A |
G |
16: 3,902,322 (GRCm39) |
S2306P |
probably damaging |
Het |
| Cspg4b |
A |
G |
13: 113,488,163 (GRCm39) |
R9G |
|
Het |
| Dcaf5 |
T |
C |
12: 80,385,807 (GRCm39) |
H773R |
probably benign |
Het |
| Dcun1d2 |
A |
T |
8: 13,311,406 (GRCm39) |
D194E |
probably benign |
Het |
| Dnah1 |
G |
T |
14: 30,989,767 (GRCm39) |
R3250S |
possibly damaging |
Het |
| Dnajc25 |
A |
C |
4: 59,020,195 (GRCm39) |
K206T |
possibly damaging |
Het |
| Dnajc27 |
T |
C |
12: 4,146,325 (GRCm39) |
L118P |
possibly damaging |
Het |
| Etl4 |
C |
T |
2: 20,714,288 (GRCm39) |
T129I |
probably damaging |
Het |
| Faap100 |
A |
G |
11: 120,263,003 (GRCm39) |
I785T |
probably damaging |
Het |
| Fam227b |
A |
T |
2: 125,830,928 (GRCm39) |
D425E |
probably benign |
Het |
| Fat4 |
C |
G |
3: 39,064,842 (GRCm39) |
L4933V |
probably damaging |
Het |
| Fbrsl1 |
A |
G |
5: 110,526,086 (GRCm39) |
F39L |
probably damaging |
Het |
| Fezf1 |
A |
G |
6: 23,247,769 (GRCm39) |
V102A |
probably benign |
Het |
| Gabra2 |
T |
C |
5: 71,170,040 (GRCm39) |
|
probably benign |
Het |
| Garnl3 |
C |
A |
2: 32,916,106 (GRCm39) |
R346L |
probably damaging |
Het |
| Grin2a |
A |
T |
16: 9,403,089 (GRCm39) |
I799N |
possibly damaging |
Het |
| Hspa4 |
A |
G |
11: 53,160,691 (GRCm39) |
F462L |
probably damaging |
Het |
| Iars1 |
C |
A |
13: 49,856,675 (GRCm39) |
|
probably benign |
Het |
| Igkv6-32 |
C |
T |
6: 70,051,063 (GRCm39) |
V98M |
possibly damaging |
Het |
| Il31ra |
A |
G |
13: 112,662,372 (GRCm39) |
F560S |
possibly damaging |
Het |
| Itpr3 |
G |
A |
17: 27,337,651 (GRCm39) |
|
probably benign |
Het |
| Kif2a |
G |
A |
13: 107,116,049 (GRCm39) |
T299I |
probably damaging |
Het |
| Leo1 |
T |
A |
9: 75,373,544 (GRCm39) |
Y656* |
probably null |
Het |
| Lpcat2 |
T |
A |
8: 93,635,864 (GRCm39) |
V422D |
probably damaging |
Het |
| Lrrcc1 |
T |
A |
3: 14,601,084 (GRCm39) |
S39T |
probably benign |
Het |
| Macf1 |
A |
T |
4: 123,405,869 (GRCm39) |
S341T |
probably benign |
Het |
| Mc2r |
T |
A |
18: 68,540,879 (GRCm39) |
Y138F |
probably damaging |
Het |
| Mepe |
A |
G |
5: 104,485,754 (GRCm39) |
N298S |
possibly damaging |
Het |
| Mmp15 |
C |
A |
8: 96,092,982 (GRCm39) |
N120K |
possibly damaging |
Het |
| Mrps9 |
A |
G |
1: 42,918,915 (GRCm39) |
R106G |
probably damaging |
Het |
| Muc16 |
T |
A |
9: 18,557,744 (GRCm39) |
M2850L |
unknown |
Het |
| Mxra8 |
T |
A |
4: 155,927,122 (GRCm39) |
I352N |
probably damaging |
Het |
| Myo16 |
G |
A |
8: 10,411,042 (GRCm39) |
V167I |
unknown |
Het |
| Neb |
T |
C |
2: 52,215,051 (GRCm39) |
D209G |
probably damaging |
Het |
| Nlgn2 |
A |
G |
11: 69,716,309 (GRCm39) |
V744A |
probably benign |
Het |
| Notch2 |
A |
G |
3: 98,029,218 (GRCm39) |
|
probably null |
Het |
| Nr1d1 |
G |
C |
11: 98,660,073 (GRCm39) |
R484G |
probably damaging |
Het |
| Or14c42-ps1 |
A |
T |
7: 86,211,147 (GRCm39) |
H69L |
unknown |
Het |
| Or5ak20 |
T |
C |
2: 85,183,953 (GRCm39) |
T106A |
probably benign |
Het |
| Or5k16 |
G |
A |
16: 58,736,843 (GRCm39) |
R54C |
probably benign |
Het |
| Or9k2b |
T |
C |
10: 130,016,702 (GRCm39) |
I16V |
probably benign |
Het |
| Oxa1l |
A |
G |
14: 54,605,248 (GRCm39) |
|
probably null |
Het |
| Piwil4 |
T |
C |
9: 14,616,322 (GRCm39) |
D15G |
|
Het |
| Plcz1 |
C |
A |
6: 139,949,612 (GRCm39) |
W461L |
probably damaging |
Het |
| Plek |
A |
T |
11: 16,944,676 (GRCm39) |
I118N |
probably damaging |
Het |
| Poc1b |
C |
A |
10: 99,000,728 (GRCm39) |
|
probably benign |
Het |
| Potefam1 |
A |
T |
2: 111,059,567 (GRCm39) |
M64K |
possibly damaging |
Het |
| Ppp1r16b |
G |
A |
2: 158,593,098 (GRCm39) |
D226N |
probably damaging |
Het |
| Prss36 |
T |
C |
7: 127,532,635 (GRCm39) |
T739A |
possibly damaging |
Het |
| Psme2 |
A |
T |
14: 55,827,074 (GRCm39) |
|
probably null |
Het |
| Ptprb |
T |
G |
10: 116,203,495 (GRCm39) |
V1802G |
probably damaging |
Het |
| Rabep2 |
C |
A |
7: 126,034,848 (GRCm39) |
Y84* |
probably null |
Het |
| Rbbp6 |
T |
G |
7: 122,600,516 (GRCm39) |
S1508A |
unknown |
Het |
| Rel |
A |
T |
11: 23,692,430 (GRCm39) |
D534E |
probably benign |
Het |
| Rpgrip1 |
G |
A |
14: 52,396,852 (GRCm39) |
S1258N |
probably damaging |
Het |
| Rprml |
T |
C |
11: 103,540,953 (GRCm39) |
L116P |
probably damaging |
Het |
| Rsph10b |
A |
G |
5: 143,887,112 (GRCm39) |
T323A |
possibly damaging |
Het |
| Rtn4rl1 |
A |
G |
11: 75,156,099 (GRCm39) |
H177R |
probably damaging |
Het |
| Sag |
A |
G |
1: 87,738,032 (GRCm39) |
T24A |
probably benign |
Het |
| Scgb2b26 |
G |
T |
7: 33,643,784 (GRCm39) |
T52N |
probably damaging |
Het |
| Scn10a |
T |
C |
9: 119,501,194 (GRCm39) |
I197V |
probably damaging |
Het |
| Sec24c |
T |
A |
14: 20,742,927 (GRCm39) |
V1003D |
possibly damaging |
Het |
| Sirt2 |
G |
A |
7: 28,471,261 (GRCm39) |
G30E |
probably damaging |
Het |
| Slc13a5 |
T |
A |
11: 72,149,919 (GRCm39) |
Q197L |
probably benign |
Het |
| Slc44a3 |
A |
T |
3: 121,283,918 (GRCm39) |
S445T |
probably damaging |
Het |
| Slc7a7 |
A |
T |
14: 54,610,449 (GRCm39) |
V399E |
probably benign |
Het |
| Smarcad1 |
T |
A |
6: 65,088,865 (GRCm39) |
D1000E |
probably benign |
Het |
| Sorcs2 |
G |
T |
5: 36,196,657 (GRCm39) |
Q663K |
probably benign |
Het |
| Stat4 |
A |
G |
1: 52,118,991 (GRCm39) |
R345G |
probably null |
Het |
| Sycp2 |
G |
A |
2: 177,992,768 (GRCm39) |
R1261C |
probably damaging |
Het |
| Tcf19 |
T |
C |
17: 35,825,381 (GRCm39) |
I259V |
probably benign |
Het |
| Thada |
T |
A |
17: 84,536,637 (GRCm39) |
R1636S |
probably benign |
Het |
| Tonsl |
G |
A |
15: 76,517,076 (GRCm39) |
T881I |
probably benign |
Het |
| Tonsl |
A |
C |
15: 76,518,263 (GRCm39) |
C570G |
probably damaging |
Het |
| Ube2o |
C |
A |
11: 116,432,273 (GRCm39) |
E898* |
probably null |
Het |
| Usp5 |
T |
C |
6: 124,794,394 (GRCm39) |
H762R |
possibly damaging |
Het |
| Vmn2r15 |
A |
G |
5: 109,434,779 (GRCm39) |
S642P |
probably benign |
Het |
| Vmn2r23 |
T |
C |
6: 123,690,431 (GRCm39) |
W436R |
probably damaging |
Het |
| Vps13d |
A |
C |
4: 144,811,977 (GRCm39) |
I3343M |
|
Het |
| Wbp11 |
T |
C |
6: 136,799,932 (GRCm39) |
K83E |
probably damaging |
Het |
| Zfp26 |
T |
A |
9: 20,356,201 (GRCm39) |
N36Y |
possibly damaging |
Het |
| Zfp57 |
T |
A |
17: 37,320,938 (GRCm39) |
I264N |
probably damaging |
Het |
|
| Other mutations in Tnrc6c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00839:Tnrc6c
|
APN |
11 |
117,605,011 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01013:Tnrc6c
|
APN |
11 |
117,612,855 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01092:Tnrc6c
|
APN |
11 |
117,612,811 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01383:Tnrc6c
|
APN |
11 |
117,605,083 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01395:Tnrc6c
|
APN |
11 |
117,613,939 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01726:Tnrc6c
|
APN |
11 |
117,640,161 (GRCm39) |
splice site |
probably benign |
|
|
IGL01869:Tnrc6c
|
APN |
11 |
117,646,274 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL02108:Tnrc6c
|
APN |
11 |
117,612,025 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02457:Tnrc6c
|
APN |
11 |
117,613,803 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02612:Tnrc6c
|
APN |
11 |
117,633,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02748:Tnrc6c
|
APN |
11 |
117,622,996 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03160:Tnrc6c
|
APN |
11 |
117,640,651 (GRCm39) |
splice site |
probably benign |
|
|
rodion
|
UTSW |
11 |
117,629,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
F5770:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
K3955:Tnrc6c
|
UTSW |
11 |
117,651,564 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0015:Tnrc6c
|
UTSW |
11 |
117,612,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0143:Tnrc6c
|
UTSW |
11 |
117,643,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0277:Tnrc6c
|
UTSW |
11 |
117,630,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0323:Tnrc6c
|
UTSW |
11 |
117,630,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0464:Tnrc6c
|
UTSW |
11 |
117,651,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0699:Tnrc6c
|
UTSW |
11 |
117,613,447 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1015:Tnrc6c
|
UTSW |
11 |
117,612,748 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1201:Tnrc6c
|
UTSW |
11 |
117,612,500 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1297:Tnrc6c
|
UTSW |
11 |
117,624,529 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1560:Tnrc6c
|
UTSW |
11 |
117,650,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1596:Tnrc6c
|
UTSW |
11 |
117,648,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnrc6c
|
UTSW |
11 |
117,651,556 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1892:Tnrc6c
|
UTSW |
11 |
117,605,188 (GRCm39) |
missense |
probably benign |
|
|
R1901:Tnrc6c
|
UTSW |
11 |
117,613,831 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1935:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1936:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1937:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1940:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3622:Tnrc6c
|
UTSW |
11 |
117,640,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3711:Tnrc6c
|
UTSW |
11 |
117,613,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3725:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3775:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3776:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3836:Tnrc6c
|
UTSW |
11 |
117,614,055 (GRCm39) |
missense |
probably benign |
0.20 |
|
R3844:Tnrc6c
|
UTSW |
11 |
117,646,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3852:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3928:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3929:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3937:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3943:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4501:Tnrc6c
|
UTSW |
11 |
117,613,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Tnrc6c
|
UTSW |
11 |
117,633,784 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4511:Tnrc6c
|
UTSW |
11 |
117,633,784 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4654:Tnrc6c
|
UTSW |
11 |
117,611,797 (GRCm39) |
missense |
probably benign |
|
|
R4765:Tnrc6c
|
UTSW |
11 |
117,633,753 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4824:Tnrc6c
|
UTSW |
11 |
117,613,731 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5004:Tnrc6c
|
UTSW |
11 |
117,611,872 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5094:Tnrc6c
|
UTSW |
11 |
117,611,872 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5130:Tnrc6c
|
UTSW |
11 |
117,629,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5234:Tnrc6c
|
UTSW |
11 |
117,651,555 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5235:Tnrc6c
|
UTSW |
11 |
117,651,555 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5345:Tnrc6c
|
UTSW |
11 |
117,614,113 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5359:Tnrc6c
|
UTSW |
11 |
117,649,731 (GRCm39) |
splice site |
silent |
|
|
R5428:Tnrc6c
|
UTSW |
11 |
117,591,588 (GRCm39) |
start codon destroyed |
probably null |
|
|
R5548:Tnrc6c
|
UTSW |
11 |
117,651,669 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5587:Tnrc6c
|
UTSW |
11 |
117,640,097 (GRCm39) |
nonsense |
probably null |
|
|
R5875:Tnrc6c
|
UTSW |
11 |
117,650,534 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5947:Tnrc6c
|
UTSW |
11 |
117,613,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6135:Tnrc6c
|
UTSW |
11 |
117,626,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6354:Tnrc6c
|
UTSW |
11 |
117,640,440 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6389:Tnrc6c
|
UTSW |
11 |
117,613,567 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7027:Tnrc6c
|
UTSW |
11 |
117,624,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7048:Tnrc6c
|
UTSW |
11 |
117,612,800 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7098:Tnrc6c
|
UTSW |
11 |
117,604,952 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7315:Tnrc6c
|
UTSW |
11 |
117,614,354 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7378:Tnrc6c
|
UTSW |
11 |
117,632,606 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7386:Tnrc6c
|
UTSW |
11 |
117,612,780 (GRCm39) |
missense |
probably benign |
|
|
R7515:Tnrc6c
|
UTSW |
11 |
117,632,507 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7665:Tnrc6c
|
UTSW |
11 |
117,611,777 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7755:Tnrc6c
|
UTSW |
11 |
117,648,912 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8824:Tnrc6c
|
UTSW |
11 |
117,630,680 (GRCm39) |
splice site |
probably benign |
|
|
R8971:Tnrc6c
|
UTSW |
11 |
117,640,089 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9261:Tnrc6c
|
UTSW |
11 |
117,605,105 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9283:Tnrc6c
|
UTSW |
11 |
117,591,630 (GRCm39) |
missense |
unknown |
|
|
R9342:Tnrc6c
|
UTSW |
11 |
117,630,720 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9633:Tnrc6c
|
UTSW |
11 |
117,638,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Tnrc6c
|
UTSW |
11 |
117,623,136 (GRCm39) |
missense |
probably benign |
|
|
V7580:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7581:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7582:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7583:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnrc6c
|
UTSW |
11 |
117,623,003 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCATGCCGTAACACAGCGTG -3'
(R):5'- GGCCTCTCTTTAACAGCTGC -3'
Sequencing Primer
(F):5'- CCGTAACACAGCGTGCAGAG -3'
(R):5'- CTTCTGTTCTTGCTGGCGAAAG -3'
|
| Posted On |
2021-03-08 |
Incidental Mutation