Mutagenetix > Incidental Mutation

Incidental Mutation 'R8751:Ahnak'

663888

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein (desmoyokin)

Synonyms

1110004P15Rik, 2310047C17Rik, DY6

MMRRC Submission

068594-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.368) question?

Stock #

R8751 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

8989284-9076919 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 9010145 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Threonine at position 2931 (K2931T)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000092956
AA Change: K2931T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: K2931T

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.1%
20x: 96.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts12	T	A	15: 11,215,727 (GRCm38)	I278N	probably damaging	Het
Adcy9	A	G	16: 4,311,628 (GRCm38)	W702R	probably damaging	Het
Adgrf5	G	A	17: 43,437,683 (GRCm38)	V468I	possibly damaging	Het
Ank3	C	T	10: 69,926,019 (GRCm38)		probably benign	Het
Birc6	G	A	17: 74,648,140 (GRCm38)	V3480I	probably damaging	Het
Bpifa5	A	T	2: 154,165,512 (GRCm38)	I125L	probably benign	Het
Catsperg2	T	C	7: 29,705,319 (GRCm38)	D773G	possibly damaging	Het
Ccm2l	A	T	2: 153,067,775 (GRCm38)	I16F	probably benign	Het
Cep72	G	A	13: 74,050,184 (GRCm38)	S359F	possibly damaging	Het
Col1a1	A	G	11: 94,947,274 (GRCm38)	N844S	unknown	Het
Col7a1	C	T	9: 108,967,662 (GRCm38)	P1623S	possibly damaging	Het
Crybg1	T	C	10: 44,004,842 (GRCm38)	K117E	probably benign	Het
Csmd3	A	G	15: 47,982,006 (GRCm38)	C54R		Het
Dlg1	A	G	16: 31,781,830 (GRCm38)	T211A	probably benign	Het
Emc1	C	A	4: 139,369,968 (GRCm38)	H724N	possibly damaging	Het
Epg5	T	A	18: 77,965,010 (GRCm38)	N784K	probably benign	Het
Epg5	A	T	18: 77,965,009 (GRCm38)	N784I	possibly damaging	Het
Epg5	A	C	18: 77,965,008 (GRCm38)	N784H	probably benign	Het
Erc2	A	G	14: 28,080,188 (GRCm38)	E771G	possibly damaging	Het
Exo1	T	C	1: 175,892,112 (GRCm38)	V241A	probably benign	Het
Fat4	A	G	3: 38,891,853 (GRCm38)	T1632A	probably benign	Het
Fbxo21	T	A	5: 118,002,062 (GRCm38)	M529K	probably damaging	Het
Fhad1	T	C	4: 141,918,823 (GRCm38)	E276G	probably benign	Het
Frem1	G	A	4: 82,970,778 (GRCm38)	T1069I	probably damaging	Het
Gapvd1	A	C	2: 34,678,066 (GRCm38)	F1429V	probably damaging	Het
Gbp9	T	C	5: 105,081,251 (GRCm38)	E510G	possibly damaging	Het
Gm17087	A	T	17: 8,566,678 (GRCm38)	H64Q	probably damaging	Het
Gm19965	A	T	1: 116,822,137 (GRCm38)	Y516F	unknown	Het
Hdac5	A	T	11: 102,218,454 (GRCm38)	I38N	probably benign	Het
Hectd4	T	A	5: 121,363,775 (GRCm38)	C4190*	probably null	Het
Helb	A	T	10: 120,089,507 (GRCm38)	D988E	probably benign	Het
Herc6	C	T	6: 57,662,374 (GRCm38)	S909L	probably damaging	Het
Ice1	A	T	13: 70,602,891 (GRCm38)	V1692E	probably damaging	Het
Ino80	A	G	2: 119,406,908 (GRCm38)	Y1107H	probably benign	Het
Kif9	A	T	9: 110,501,656 (GRCm38)	Y350F	probably benign	Het
Lct	T	A	1: 128,293,797 (GRCm38)	T1570S	probably benign	Het
Lias	T	A	5: 65,399,850 (GRCm38)	N203K	probably benign	Het
Lrrtm4	A	G	6: 80,022,109 (GRCm38)	N168S	probably damaging	Het
Ltf	A	T	9: 111,031,124 (GRCm38)	K538*	probably null	Het
Lysmd4	A	G	7: 67,226,039 (GRCm38)	D150G	probably benign	Het
Magi2	A	G	5: 20,534,464 (GRCm38)	D572G	probably benign	Het
Meiob	T	C	17: 24,828,034 (GRCm38)		probably null	Het
Mettl11b	T	A	1: 163,717,169 (GRCm38)	T82S	probably benign	Het
Ncor2	T	C	5: 125,038,900 (GRCm38)	Y130C		Het
Ofcc1	A	G	13: 40,255,596 (GRCm38)	S118P	probably benign	Het
Olfr1512	A	G	14: 52,372,963 (GRCm38)	F30S	probably benign	Het
Olfr315	A	G	11: 58,778,387 (GRCm38)	T87A	probably benign	Het
Olfr922	T	A	9: 38,816,039 (GRCm38)	C179S	probably damaging	Het
Parp14	A	T	16: 35,856,811 (GRCm38)	M929K	probably benign	Het
Pcdh8	T	C	14: 79,768,789 (GRCm38)	E778G	probably benign	Het
Pgls	T	C	8: 71,595,194 (GRCm38)	V211A	probably benign	Het
Pkd2	T	A	5: 104,489,285 (GRCm38)	M588K	probably damaging	Het
Pms1	T	C	1: 53,192,110 (GRCm38)	N860S	probably benign	Het
Psg19	C	T	7: 18,796,963 (GRCm38)	V89M	probably benign	Het
Reln	T	C	5: 21,942,674 (GRCm38)	H2426R	probably benign	Het
Ripor2	T	A	13: 24,701,067 (GRCm38)	N428K	possibly damaging	Het
Slc12a4	C	T	8: 105,949,653 (GRCm38)		probably null	Het
Slc25a3	T	C	10: 91,117,098 (GRCm38)	I314V	probably benign	Het
Slc29a1	C	A	17: 45,589,762 (GRCm38)	V125F	probably benign	Het
Slc9a5	T	A	8: 105,359,349 (GRCm38)	C583S	probably damaging	Het
Slco2b1	G	A	7: 99,660,052 (GRCm38)	Q691*	probably null	Het
Smg7	T	C	1: 152,843,378 (GRCm38)	D874G	probably damaging	Het
Spef2	T	A	15: 9,729,637 (GRCm38)	K132*	probably null	Het
Tap1	A	G	17: 34,193,159 (GRCm38)	K446R	probably benign	Het
Tcam1	A	T	11: 106,285,617 (GRCm38)	T390S	possibly damaging	Het
Tnik	A	G	3: 28,611,908 (GRCm38)	N687D	probably damaging	Het
Trim42	T	C	9: 97,369,799 (GRCm38)	R16G	possibly damaging	Het
Vcp	A	C	4: 42,984,658 (GRCm38)	L411W	probably damaging	Het
Vma21-ps	C	A	4: 52,496,973 (GRCm38)	G91V	probably damaging	Het
Vmn1r23	T	C	6: 57,926,467 (GRCm38)	T109A	probably benign	Het
Vmn2r67	C	T	7: 85,152,242 (GRCm38)	C162Y	probably benign	Het
Vmn2r-ps117	A	G	17: 18,823,759 (GRCm38)	T366A	probably benign	Het
Zfp804a	A	G	2: 82,235,846 (GRCm38)	K54E	probably damaging	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	9,007,223 (GRCm38)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	9,009,951 (GRCm38)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	9,007,908 (GRCm38)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	9,004,307 (GRCm38)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	9,013,383 (GRCm38)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	9,013,730 (GRCm38)	nonsense	probably null
IGL00807:Ahnak	APN	19	9,008,522 (GRCm38)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	9,013,698 (GRCm38)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	9,012,887 (GRCm38)	intron	probably benign
IGL01118:Ahnak	APN	19	9,012,578 (GRCm38)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	9,002,494 (GRCm38)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	9,003,032 (GRCm38)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	9,011,703 (GRCm38)	missense	probably benign
IGL01541:Ahnak	APN	19	9,007,879 (GRCm38)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	9,002,839 (GRCm38)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	9,003,501 (GRCm38)	nonsense	probably null
IGL01746:Ahnak	APN	19	9,004,912 (GRCm38)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	9,000,118 (GRCm38)	missense	unknown
IGL01821:Ahnak	APN	19	9,012,118 (GRCm38)	missense	probably benign
IGL01913:Ahnak	APN	19	9,006,064 (GRCm38)	nonsense	probably null
IGL01934:Ahnak	APN	19	9,002,657 (GRCm38)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	9,006,557 (GRCm38)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	9,014,909 (GRCm38)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	9,002,855 (GRCm38)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	9,008,268 (GRCm38)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	9,005,987 (GRCm38)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	9,014,833 (GRCm38)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	9,004,016 (GRCm38)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	9,004,933 (GRCm38)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	9,003,308 (GRCm38)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	9,005,627 (GRCm38)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	9,012,077 (GRCm38)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	9,012,584 (GRCm38)	nonsense	probably null
IGL02717:Ahnak	APN	19	9,002,387 (GRCm38)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	9,009,707 (GRCm38)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	9,004,593 (GRCm38)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	9,002,596 (GRCm38)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	9,011,918 (GRCm38)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	9,006,508 (GRCm38)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	9,003,547 (GRCm38)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	9,005,212 (GRCm38)	intron	probably benign
IGL03176:Ahnak	APN	19	9,002,449 (GRCm38)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	9,008,166 (GRCm38)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	9,011,239 (GRCm38)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	9,009,325 (GRCm38)	intron	probably benign
IGL03371:Ahnak	APN	19	9,004,228 (GRCm38)	missense	possibly damaging	0.91
Eskimo	UTSW	19	9,009,574 (GRCm38)	missense	probably benign	0.31
Nanook	UTSW	19	9,003,231 (GRCm38)	missense	probably benign	0.42
Netsilik	UTSW	19	9,002,321 (GRCm38)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	9,002,387 (GRCm38)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	9,006,176 (GRCm38)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	9,012,056 (GRCm38)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	9,013,893 (GRCm38)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0141:Ahnak	UTSW	19	9,006,680 (GRCm38)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	9,005,725 (GRCm38)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	9,002,495 (GRCm38)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	9,008,350 (GRCm38)	nonsense	probably null
R0386:Ahnak	UTSW	19	9,011,144 (GRCm38)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	9,015,116 (GRCm38)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	9,012,871 (GRCm38)	intron	probably benign
R0463:Ahnak	UTSW	19	9,009,407 (GRCm38)	intron	probably benign
R0469:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0470:Ahnak	UTSW	19	9,008,967 (GRCm38)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	9,014,120 (GRCm38)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	9,007,151 (GRCm38)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	9,000,264 (GRCm38)	splice site	probably benign
R0506:Ahnak	UTSW	19	9,009,128 (GRCm38)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0557:Ahnak	UTSW	19	9,001,944 (GRCm38)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	9,013,698 (GRCm38)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	9,007,878 (GRCm38)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	9,013,402 (GRCm38)	nonsense	probably null
R0659:Ahnak	UTSW	19	9,015,002 (GRCm38)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	9,016,734 (GRCm38)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	9,016,734 (GRCm38)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	9,005,063 (GRCm38)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	9,006,433 (GRCm38)	nonsense	probably null
R0941:Ahnak	UTSW	19	9,009,914 (GRCm38)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	9,012,848 (GRCm38)	intron	probably benign
R1017:Ahnak	UTSW	19	9,010,543 (GRCm38)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	9,007,618 (GRCm38)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	9,013,125 (GRCm38)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	9,005,620 (GRCm38)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	9,004,245 (GRCm38)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	9,013,926 (GRCm38)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	9,015,619 (GRCm38)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	9,002,883 (GRCm38)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	9,004,169 (GRCm38)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	9,015,631 (GRCm38)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	9,007,082 (GRCm38)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	9,004,896 (GRCm38)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	9,004,896 (GRCm38)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	9,015,875 (GRCm38)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	9,015,875 (GRCm38)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	9,012,932 (GRCm38)	intron	probably benign
R1507:Ahnak	UTSW	19	9,010,077 (GRCm38)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	9,004,728 (GRCm38)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	9,002,375 (GRCm38)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	9,004,094 (GRCm38)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	9,008,987 (GRCm38)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	9,009,449 (GRCm38)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	9,009,963 (GRCm38)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	9,011,809 (GRCm38)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	9,010,655 (GRCm38)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	9,013,753 (GRCm38)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	9,002,438 (GRCm38)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	9,004,905 (GRCm38)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	9,005,867 (GRCm38)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	9,013,832 (GRCm38)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	9,002,048 (GRCm38)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	9,015,979 (GRCm38)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	9,007,088 (GRCm38)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	9,007,088 (GRCm38)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	9,017,881 (GRCm38)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	9,007,922 (GRCm38)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	9,015,083 (GRCm38)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	9,015,251 (GRCm38)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	9,007,075 (GRCm38)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	9,014,573 (GRCm38)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	9,013,181 (GRCm38)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	9,014,300 (GRCm38)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	9,007,056 (GRCm38)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	9,008,041 (GRCm38)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	9,011,557 (GRCm38)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	9,000,684 (GRCm38)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	9,011,494 (GRCm38)	nonsense	probably null
R2208:Ahnak	UTSW	19	9,017,732 (GRCm38)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	9,012,991 (GRCm38)	intron	probably benign
R2268:Ahnak	UTSW	19	9,010,574 (GRCm38)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	9,009,256 (GRCm38)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	9,002,851 (GRCm38)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	9,011,654 (GRCm38)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	9,011,654 (GRCm38)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	9,000,148 (GRCm38)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	9,009,944 (GRCm38)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	9,010,177 (GRCm38)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	9,006,752 (GRCm38)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	9,005,708 (GRCm38)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	9,006,958 (GRCm38)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	9,009,994 (GRCm38)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	9,007,898 (GRCm38)	missense	probably benign
R3723:Ahnak	UTSW	19	9,016,853 (GRCm38)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	9,009,023 (GRCm38)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	9,010,859 (GRCm38)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	9,010,859 (GRCm38)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	9,011,299 (GRCm38)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	9,014,327 (GRCm38)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	9,002,600 (GRCm38)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	9,000,786 (GRCm38)	nonsense	probably null
R4237:Ahnak	UTSW	19	9,001,783 (GRCm38)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	9,016,839 (GRCm38)	nonsense	probably null
R4331:Ahnak	UTSW	19	9,015,820 (GRCm38)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	9,012,083 (GRCm38)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	9,003,040 (GRCm38)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	9,014,930 (GRCm38)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	9,010,825 (GRCm38)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	9,003,724 (GRCm38)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	9,008,701 (GRCm38)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	9,004,855 (GRCm38)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	9,004,681 (GRCm38)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	9,012,258 (GRCm38)	intron	probably benign
R4704:Ahnak	UTSW	19	9,013,181 (GRCm38)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	9,016,906 (GRCm38)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	9,016,735 (GRCm38)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	9,007,301 (GRCm38)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	9,007,301 (GRCm38)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	9,011,975 (GRCm38)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	9,012,499 (GRCm38)	intron	probably benign
R4832:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R4882:Ahnak	UTSW	19	9,005,897 (GRCm38)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	9,012,754 (GRCm38)	intron	probably benign
R4895:Ahnak	UTSW	19	9,017,441 (GRCm38)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	9,010,967 (GRCm38)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	9,017,835 (GRCm38)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	9,015,100 (GRCm38)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	9,010,631 (GRCm38)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	9,012,458 (GRCm38)	intron	probably benign
R5073:Ahnak	UTSW	19	9,003,231 (GRCm38)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	9,014,759 (GRCm38)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	9,013,644 (GRCm38)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	9,017,087 (GRCm38)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	9,004,655 (GRCm38)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	9,010,904 (GRCm38)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	9,017,569 (GRCm38)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	9,015,665 (GRCm38)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	9,000,684 (GRCm38)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	9,015,341 (GRCm38)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	9,016,735 (GRCm38)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	9,003,691 (GRCm38)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	9,007,175 (GRCm38)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	9,006,917 (GRCm38)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	9,009,476 (GRCm38)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	9,013,094 (GRCm38)	nonsense	probably null
R5643:Ahnak	UTSW	19	9,010,657 (GRCm38)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	9,010,657 (GRCm38)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	9,014,615 (GRCm38)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	9,002,519 (GRCm38)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	9,001,840 (GRCm38)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	9,016,747 (GRCm38)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	9,010,253 (GRCm38)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	9,001,732 (GRCm38)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	9,013,562 (GRCm38)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	9,002,321 (GRCm38)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	9,015,248 (GRCm38)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	9,012,382 (GRCm38)	nonsense	probably null
R5808:Ahnak	UTSW	19	9,010,235 (GRCm38)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	9,010,052 (GRCm38)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	9,008,342 (GRCm38)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	9,018,211 (GRCm38)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	9,013,767 (GRCm38)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	9,011,903 (GRCm38)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	9,015,182 (GRCm38)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	9,016,585 (GRCm38)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	9,009,347 (GRCm38)	intron	probably benign
R6000:Ahnak	UTSW	19	9,013,111 (GRCm38)	nonsense	probably null
R6005:Ahnak	UTSW	19	9,015,161 (GRCm38)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	9,004,099 (GRCm38)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	9,004,099 (GRCm38)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	9,012,963 (GRCm38)	intron	probably benign
R6209:Ahnak	UTSW	19	9,012,566 (GRCm38)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	9,013,583 (GRCm38)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	9,008,025 (GRCm38)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	9,018,277 (GRCm38)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	9,015,003 (GRCm38)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	9,003,305 (GRCm38)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	9,006,626 (GRCm38)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	9,007,148 (GRCm38)	missense	probably benign	0.11
R6331:Ahnak	UTSW	19	9,006,625 (GRCm38)	missense	probably benign	0.18
R6355:Ahnak	UTSW	19	9,008,762 (GRCm38)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	9,009,574 (GRCm38)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	9,008,806 (GRCm38)	missense	probably benign	0.27
R6572:Ahnak	UTSW	19	9,007,976 (GRCm38)	missense	probably damaging	0.99
R6574:Ahnak	UTSW	19	9,017,047 (GRCm38)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	9,009,581 (GRCm38)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	9,015,310 (GRCm38)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	9,009,581 (GRCm38)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	9,011,562 (GRCm38)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	9,007,561 (GRCm38)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	9,011,857 (GRCm38)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	9,015,235 (GRCm38)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,037,168 (GRCm38)	nonsense	probably null
R6863:Ahnak	UTSW	19	9,012,365 (GRCm38)	intron	probably benign
R6876:Ahnak	UTSW	19	9,014,120 (GRCm38)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	9,015,215 (GRCm38)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	9,002,359 (GRCm38)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	9,013,488 (GRCm38)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	9,017,668 (GRCm38)	missense	probably damaging	1.00
R7202:Ahnak	UTSW	19	9,017,799 (GRCm38)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	9,012,488 (GRCm38)	missense	unknown
R7241:Ahnak	UTSW	19	9,009,031 (GRCm38)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	9,006,617 (GRCm38)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	9,002,143 (GRCm38)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	9,009,827 (GRCm38)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	9,001,792 (GRCm38)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	9,008,165 (GRCm38)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	9,003,205 (GRCm38)	missense	probably benign	0.02
R7400:Ahnak	UTSW	19	9,014,613 (GRCm38)	missense	probably damaging	0.99
R7444:Ahnak	UTSW	19	9,007,423 (GRCm38)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	9,004,822 (GRCm38)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	9,012,019 (GRCm38)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	9,002,351 (GRCm38)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	9,002,322 (GRCm38)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	9,006,824 (GRCm38)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	9,011,165 (GRCm38)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	9,016,156 (GRCm38)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	9,000,786 (GRCm38)	nonsense	probably null
R7583:Ahnak	UTSW	19	9,006,093 (GRCm38)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	9,004,574 (GRCm38)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	9,015,047 (GRCm38)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	9,009,315 (GRCm38)	missense	unknown
R7827:Ahnak	UTSW	19	9,005,344 (GRCm38)	nonsense	probably null
R7857:Ahnak	UTSW	19	9,007,468 (GRCm38)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	9,005,832 (GRCm38)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	9,014,084 (GRCm38)	nonsense	probably null
R7959:Ahnak	UTSW	19	9,010,649 (GRCm38)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	9,012,800 (GRCm38)	missense	unknown
R7979:Ahnak	UTSW	19	9,011,432 (GRCm38)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	9,012,083 (GRCm38)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	9,009,335 (GRCm38)	missense	unknown
R8033:Ahnak	UTSW	19	9,003,710 (GRCm38)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	9,007,123 (GRCm38)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	9,011,876 (GRCm38)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	9,000,100 (GRCm38)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	9,004,679 (GRCm38)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	9,002,255 (GRCm38)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	9,010,436 (GRCm38)	nonsense	probably null
R8241:Ahnak	UTSW	19	9,007,295 (GRCm38)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	9,001,946 (GRCm38)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	9,005,453 (GRCm38)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	9,009,662 (GRCm38)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	9,017,855 (GRCm38)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	9,008,749 (GRCm38)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	9,012,355 (GRCm38)	missense	unknown
R8528:Ahnak	UTSW	19	9,007,728 (GRCm38)	missense	probably damaging	1.00
R8549:Ahnak	UTSW	19	9,011,483 (GRCm38)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	9,005,996 (GRCm38)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	9,009,074 (GRCm38)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	9,013,346 (GRCm38)	nonsense	probably null
R8752:Ahnak	UTSW	19	9,015,537 (GRCm38)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	9,011,473 (GRCm38)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	9,006,890 (GRCm38)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	9,007,203 (GRCm38)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	9,000,742 (GRCm38)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	9,009,088 (GRCm38)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	9,011,735 (GRCm38)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	9,012,737 (GRCm38)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	9,004,113 (GRCm38)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	9,010,123 (GRCm38)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	9,007,253 (GRCm38)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	9,008,526 (GRCm38)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	9,010,347 (GRCm38)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	9,009,785 (GRCm38)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	9,014,923 (GRCm38)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	9,010,883 (GRCm38)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	9,012,579 (GRCm38)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	9,016,139 (GRCm38)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R9325:Ahnak	UTSW	19	9,013,893 (GRCm38)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R9340:Ahnak	UTSW	19	9,017,047 (GRCm38)	missense	probably benign	0.04
R9351:Ahnak	UTSW	19	9,007,868 (GRCm38)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	9,012,902 (GRCm38)	missense	unknown
R9462:Ahnak	UTSW	19	9,003,935 (GRCm38)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	9,010,861 (GRCm38)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	9,002,074 (GRCm38)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	9,010,094 (GRCm38)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,037,253 (GRCm38)	missense
R9534:Ahnak	UTSW	19	9,003,612 (GRCm38)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	9,003,785 (GRCm38)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	9,011,798 (GRCm38)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	9,012,482 (GRCm38)	missense	unknown
R9649:Ahnak	UTSW	19	9,008,422 (GRCm38)	nonsense	probably null
R9683:Ahnak	UTSW	19	9,007,355 (GRCm38)	missense	possibly damaging	0.94
R9691:Ahnak	UTSW	19	9,011,726 (GRCm38)	missense	possibly damaging	0.49
R9712:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9712:Ahnak	UTSW	19	9,007,028 (GRCm38)	small deletion	probably benign
R9713:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9715:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9725:Ahnak	UTSW	19	9,014,243 (GRCm38)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	9,004,169 (GRCm38)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	9,010,177 (GRCm38)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	9,013,619 (GRCm38)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	9,013,601 (GRCm38)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	9,013,619 (GRCm38)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	9,012,037 (GRCm38)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	9,016,082 (GRCm38)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	9,008,856 (GRCm38)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	9,017,468 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GATGTGGATGTTCATGGCCC -3'
(R):5'- ACCATGAACATCAATATCTGGAGC -3'

Sequencing Primer
(F):5'- ATGTTCATGGCCCAGACTG -3'
(R):5'- GGAGCATTTACATCTAATTTTGGGC -3'

Posted On

2021-03-08