Mutagenetix > Incidental Mutation

Incidental Mutation 'R8753:Nbeal1'

663949

Institutional Source

Beutler Lab

Gene Symbol

Nbeal1

Ensembl Gene

ENSMUSG00000073664

Gene Name

neurobeachin like 1

Synonyms

A530083I02Rik, A530050O19Rik, ALS2CR17, 2310076G13Rik

MMRRC Submission

068619-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8753 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

60219758-60377487 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 60307542 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 1685 (I1685F)

Ref Sequence

ENSEMBL: ENSMUSP00000124056 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160834] [ENSMUST00000162291]

AlphaFold

E9PYP2

Predicted Effect

SMART Domains

Protein: ENSMUSP00000049393
Gene: ENSMUSG00000073664
AA Change: I418F

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
low complexity region	719	735	N/A	INTRINSIC
Pfam:DUF4704	851	1130	3.4e-39	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
Pfam:DUF4800	1575	1828	6.3e-126	PFAM
coiled coil region	1859	1882	N/A	INTRINSIC
Pfam:PH_BEACH	1889	1975	2e-24	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000160834
AA Change: I1685F

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000124056
Gene: ENSMUSG00000073664
AA Change: I1685F

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
Pfam:Laminin_G_3	567	801	8.3e-9	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
low complexity region	1849	1865	N/A	INTRINSIC
Pfam:PH_BEACH	1882	1975	4.9e-32	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000162291
AA Change: I416F

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000125592
Gene: ENSMUSG00000073664
AA Change: I416F

Domain	Start	End	E-Value	Type
low complexity region	114	132	N/A	INTRINSIC
low complexity region	580	596	N/A	INTRINSIC
Pfam:PH_BEACH	613	706	9.6e-33	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.9%

Validation Efficiency

95% (59/62)

Allele List at MGI

All alleles(16) : Targeted(1) Gene trapped(15)

Other mutations in this stock

Total: 62 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca2	T	C	2: 25,332,706 (GRCm39)	Y1496H	probably damaging	Het
Acan	G	A	7: 78,748,516 (GRCm39)	E1096K	possibly damaging	Het
Adprhl1	T	C	8: 13,272,118 (GRCm39)	K1547E	possibly damaging	Het
Ampd2	C	A	3: 107,987,432 (GRCm39)	V134L	probably benign	Het
Arf4	T	A	14: 26,374,114 (GRCm39)		probably benign	Het
Boc	A	T	16: 44,320,775 (GRCm39)	M295K		Het
C2cd3	T	A	7: 100,049,024 (GRCm39)		probably null	Het
Calcrl	C	G	2: 84,178,659 (GRCm39)	G223A	probably benign	Het
Calcrl	C	A	2: 84,178,661 (GRCm39)	M222I	probably benign	Het
Ccdc88b	T	C	19: 6,833,213 (GRCm39)	E278G	probably damaging	Het
Ccz1	A	G	5: 143,925,050 (GRCm39)	C469R	probably benign	Het
Cdc40	C	T	10: 40,717,480 (GRCm39)	D404N	probably damaging	Het
Clpx	G	A	9: 65,223,958 (GRCm39)	G251S	probably damaging	Het
Col6a3	C	G	1: 90,695,328 (GRCm39)		probably benign	Het
Cpox	T	A	16: 58,498,391 (GRCm39)	M408K	probably damaging	Het
Crybb3	A	G	5: 113,226,247 (GRCm39)		probably null	Het
Cubn	A	T	2: 13,313,377 (GRCm39)	C3064*	probably null	Het
Cxcl3	CCTGCTGCTGCTGCTG	CCTGCTGCTGCTG	5: 90,934,071 (GRCm39)		probably benign	Het
Cyp4a31	A	T	4: 115,432,158 (GRCm39)	S432C	probably benign	Het
Ddias	A	T	7: 92,508,668 (GRCm39)	F416I	probably damaging	Het
Dlat	G	T	9: 50,560,967 (GRCm39)	A360E	probably damaging	Het
Dnttip2	A	G	3: 122,074,398 (GRCm39)	T612A	probably damaging	Het
Fnip1	A	G	11: 54,400,867 (GRCm39)	T1089A	probably damaging	Het
Gm12117	A	T	11: 33,225,953 (GRCm39)	L128M	probably benign	Het
Gtf2h5	C	CA	17: 6,134,833 (GRCm39)		probably null	Het
Ibtk	T	C	9: 85,610,819 (GRCm39)	T285A	probably benign	Het
Ifi206	A	T	1: 173,301,223 (GRCm39)	N818K	unknown	Het
Itga10	T	G	3: 96,558,471 (GRCm39)	L305R	probably damaging	Het
Khnyn	T	C	14: 56,125,223 (GRCm39)	Y461H	possibly damaging	Het
Macroh2a2	T	C	10: 61,585,113 (GRCm39)	D177G	possibly damaging	Het
Mbtps1	T	C	8: 120,235,601 (GRCm39)	S1026G	possibly damaging	Het
Msantd4	A	G	9: 4,385,013 (GRCm39)	E246G	probably damaging	Het
N4bp1	T	C	8: 87,575,085 (GRCm39)	I737V	probably damaging	Het
Nav2	T	G	7: 49,102,320 (GRCm39)	S373A	probably benign	Het
Nbea	T	C	3: 55,534,329 (GRCm39)	Y2936C	probably damaging	Het
Nt5c3	C	G	6: 56,860,677 (GRCm39)	G293R	probably damaging	Het
Or4f14c	A	T	2: 111,940,802 (GRCm39)	V265E	probably benign	Het
Or52z1	T	A	7: 103,436,567 (GRCm39)	I306F	probably benign	Het
Pcnx2	A	T	8: 126,613,999 (GRCm39)	V484E	probably benign	Het
Pcsk5	C	T	19: 17,446,408 (GRCm39)	R1195Q	probably benign	Het
Perm1	TGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCT	TGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCT	4: 156,302,525 (GRCm39)		probably benign	Het
Pitpnm3	A	G	11: 71,942,704 (GRCm39)	V861A	probably benign	Het
Pkd1	A	G	17: 24,793,176 (GRCm39)	Y1621C	probably damaging	Het
Polr3a	C	A	14: 24,513,702 (GRCm39)	E846*	probably null	Het
Polr3e	T	C	7: 120,539,540 (GRCm39)	V455A	possibly damaging	Het
Prr5l	C	T	2: 101,571,723 (GRCm39)	G118D	probably damaging	Het
Pygl	G	T	12: 70,242,400 (GRCm39)	N685K	probably damaging	Het
Rfx8	A	G	1: 39,757,600 (GRCm39)	V56A	probably damaging	Het
Sbf1	T	C	15: 89,179,662 (GRCm39)	D1341G	probably benign	Het
Selenon	T	C	4: 134,275,330 (GRCm39)	T123A	probably benign	Het
Slc23a1	T	G	18: 35,752,631 (GRCm39)	K549Q	probably benign	Het
Slc7a13	T	C	4: 19,841,443 (GRCm39)	F430S	probably damaging	Het
Smarcc2	G	A	10: 128,319,070 (GRCm39)	V707M	probably damaging	Het
St18	A	G	1: 6,916,015 (GRCm39)	S887G	probably damaging	Het
T2	T	C	17: 8,615,477 (GRCm39)		probably benign	Het
Tbc1d16	A	G	11: 119,101,492 (GRCm39)	L6P	probably damaging	Het
Tcf7l2	T	C	19: 55,920,195 (GRCm39)	L576P	possibly damaging	Het
Tnr	A	G	1: 159,677,936 (GRCm39)	D107G	probably benign	Het
Trpv1	G	T	11: 73,135,082 (GRCm39)	K426N	probably damaging	Het
Vmn1r15	A	T	6: 57,235,895 (GRCm39)	L254F	probably benign	Het
Vmn1r219	A	T	13: 23,347,191 (GRCm39)	I127F	probably damaging	Het
Zc3h14	A	T	12: 98,724,831 (GRCm39)	E164D	probably benign	Het

Other mutations in Nbeal1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Nbeal1	APN	1	60,274,350 (GRCm39)	nonsense	probably null	0.00
IGL00334:Nbeal1	APN	1	60,321,042 (GRCm39)	missense	probably damaging	0.98
IGL00334:Nbeal1	APN	1	60,367,262 (GRCm39)	missense	probably damaging	1.00
IGL00514:Nbeal1	APN	1	60,256,384 (GRCm39)	missense	probably benign	0.31
IGL00596:Nbeal1	APN	1	60,220,900 (GRCm39)	missense	probably damaging	0.96
IGL00654:Nbeal1	APN	1	60,234,170 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL00757:Nbeal1	APN	1	60,234,302 (GRCm39)	missense	possibly damaging	0.82
IGL00771:Nbeal1	APN	1	60,274,512 (GRCm39)	missense	probably benign	0.11
IGL01315:Nbeal1	APN	1	60,320,500 (GRCm39)	missense	probably damaging	1.00
IGL01445:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01456:Nbeal1	APN	1	60,269,787 (GRCm39)	missense	probably damaging	1.00
IGL01458:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01535:Nbeal1	APN	1	60,256,414 (GRCm39)	missense	probably damaging	1.00
IGL01608:Nbeal1	APN	1	60,281,694 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL02006:Nbeal1	APN	1	60,311,418 (GRCm39)	critical splice donor site	probably null
IGL02105:Nbeal1	APN	1	60,292,660 (GRCm39)	missense	probably damaging	1.00
IGL02409:Nbeal1	APN	1	60,368,494 (GRCm39)	missense	probably benign	0.01
IGL02713:Nbeal1	APN	1	60,274,396 (GRCm39)	missense	possibly damaging	0.94
IGL02720:Nbeal1	APN	1	60,323,146 (GRCm39)	missense	probably damaging	0.98
IGL02887:Nbeal1	APN	1	60,326,603 (GRCm39)	splice site	probably benign
IGL02945:Nbeal1	APN	1	60,245,569 (GRCm39)	missense	probably damaging	1.00
IGL03023:Nbeal1	APN	1	60,292,572 (GRCm39)	missense	probably damaging	0.98
IGL03114:Nbeal1	APN	1	60,317,886 (GRCm39)	missense	probably damaging	1.00
IGL03231:Nbeal1	APN	1	60,275,618 (GRCm39)	missense	probably benign	0.44
IGL03241:Nbeal1	APN	1	60,274,027 (GRCm39)	missense	possibly damaging	0.46
IGL03241:Nbeal1	APN	1	60,274,028 (GRCm39)	missense	probably benign	0.44
IGL03382:Nbeal1	APN	1	60,300,745 (GRCm39)	critical splice donor site	probably null
IGL03412:Nbeal1	APN	1	60,281,726 (GRCm39)	nonsense	probably null
coach	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
Committee	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
Disgrace	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
Dravrah	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
Harvard	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
horrified	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
Lampoon	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
lawyer	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
magistrate	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
Maratimus	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
National	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
phainopepla	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R3875_Nbeal1_770	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
satirical	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
silky	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
stiggs	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
3-1:Nbeal1	UTSW	1	60,303,431 (GRCm39)	splice site	probably benign
P0007:Nbeal1	UTSW	1	60,358,847 (GRCm39)	missense	probably damaging	0.98
P0028:Nbeal1	UTSW	1	60,331,096 (GRCm39)	missense	probably damaging	1.00
R0041:Nbeal1	UTSW	1	60,321,030 (GRCm39)	missense	probably benign	0.05
R0051:Nbeal1	UTSW	1	60,349,422 (GRCm39)	missense	probably benign	0.19
R0052:Nbeal1	UTSW	1	60,267,771 (GRCm39)	splice site	probably benign
R0054:Nbeal1	UTSW	1	60,326,560 (GRCm39)	utr 3 prime	probably benign
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0094:Nbeal1	UTSW	1	60,344,468 (GRCm39)	missense	possibly damaging	0.62
R0310:Nbeal1	UTSW	1	60,344,529 (GRCm39)	splice site	probably benign
R0324:Nbeal1	UTSW	1	60,332,032 (GRCm39)	missense	probably damaging	1.00
R0329:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0330:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0417:Nbeal1	UTSW	1	60,286,893 (GRCm39)	missense	probably benign	0.00
R0421:Nbeal1	UTSW	1	60,307,598 (GRCm39)	missense	probably benign	0.08
R0617:Nbeal1	UTSW	1	60,320,991 (GRCm39)	nonsense	probably null
R1034:Nbeal1	UTSW	1	60,329,165 (GRCm39)	nonsense	probably null
R1082:Nbeal1	UTSW	1	60,351,385 (GRCm39)	missense	probably damaging	0.99
R1123:Nbeal1	UTSW	1	60,299,428 (GRCm39)	missense	probably benign
R1187:Nbeal1	UTSW	1	60,233,687 (GRCm39)	missense	probably damaging	1.00
R1484:Nbeal1	UTSW	1	60,240,098 (GRCm39)	missense	probably damaging	1.00
R1594:Nbeal1	UTSW	1	60,344,450 (GRCm39)	missense	possibly damaging	0.91
R1651:Nbeal1	UTSW	1	60,239,278 (GRCm39)	missense	probably damaging	1.00
R1678:Nbeal1	UTSW	1	60,299,493 (GRCm39)	missense	probably benign	0.00
R1806:Nbeal1	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
R1937:Nbeal1	UTSW	1	60,307,100 (GRCm39)	nonsense	probably null
R1952:Nbeal1	UTSW	1	60,273,999 (GRCm39)	missense	probably damaging	1.00
R1953:Nbeal1	UTSW	1	60,273,999 (GRCm39)	missense	probably damaging	1.00
R2038:Nbeal1	UTSW	1	60,245,503 (GRCm39)	missense	probably benign	0.00
R2044:Nbeal1	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R2050:Nbeal1	UTSW	1	60,332,123 (GRCm39)	splice site	probably null
R2055:Nbeal1	UTSW	1	60,350,216 (GRCm39)	missense	probably damaging	1.00
R2064:Nbeal1	UTSW	1	60,309,515 (GRCm39)	missense	possibly damaging	0.89
R2100:Nbeal1	UTSW	1	60,344,430 (GRCm39)	splice site	probably null
R2181:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R2192:Nbeal1	UTSW	1	60,321,054 (GRCm39)	missense	probably damaging	1.00
R2203:Nbeal1	UTSW	1	60,323,165 (GRCm39)	missense	probably benign	0.21
R2267:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2268:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2351:Nbeal1	UTSW	1	60,276,257 (GRCm39)	missense	possibly damaging	0.90
R2366:Nbeal1	UTSW	1	60,290,511 (GRCm39)	missense	probably damaging	0.97
R2393:Nbeal1	UTSW	1	60,290,529 (GRCm39)	missense	probably damaging	0.98
R3545:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3546:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3547:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3701:Nbeal1	UTSW	1	60,290,572 (GRCm39)	splice site	probably benign
R3747:Nbeal1	UTSW	1	60,234,182 (GRCm39)	missense	probably damaging	0.98
R3875:Nbeal1	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
R4119:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R4256:Nbeal1	UTSW	1	60,370,107 (GRCm39)	missense	probably benign	0.19
R4371:Nbeal1	UTSW	1	60,329,105 (GRCm39)	missense	possibly damaging	0.95
R4450:Nbeal1	UTSW	1	60,306,933 (GRCm39)	missense	probably damaging	0.97
R4558:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R4618:Nbeal1	UTSW	1	60,267,890 (GRCm39)	intron	probably benign
R4673:Nbeal1	UTSW	1	60,368,549 (GRCm39)	missense	probably damaging	1.00
R4719:Nbeal1	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
R4798:Nbeal1	UTSW	1	60,261,352 (GRCm39)	splice site	probably null
R4826:Nbeal1	UTSW	1	60,290,501 (GRCm39)	missense	possibly damaging	0.79
R4841:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4842:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4895:Nbeal1	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
R4929:Nbeal1	UTSW	1	60,277,813 (GRCm39)	missense	probably damaging	1.00
R5026:Nbeal1	UTSW	1	60,276,338 (GRCm39)	missense	probably damaging	1.00
R5243:Nbeal1	UTSW	1	60,309,487 (GRCm39)	missense	probably damaging	0.99
R5300:Nbeal1	UTSW	1	60,274,718 (GRCm39)	nonsense	probably null
R5345:Nbeal1	UTSW	1	60,367,369 (GRCm39)	critical splice donor site	probably null
R5502:Nbeal1	UTSW	1	60,350,158 (GRCm39)	missense	probably damaging	1.00
R5542:Nbeal1	UTSW	1	60,316,353 (GRCm39)	missense	probably benign	0.00
R5555:Nbeal1	UTSW	1	60,276,311 (GRCm39)	missense	possibly damaging	0.93
R5580:Nbeal1	UTSW	1	60,281,761 (GRCm39)	missense	probably benign	0.45
R5765:Nbeal1	UTSW	1	60,331,006 (GRCm39)	missense	probably damaging	1.00
R5802:Nbeal1	UTSW	1	60,311,380 (GRCm39)	missense	probably benign	0.01
R5907:Nbeal1	UTSW	1	60,267,950 (GRCm39)	intron	probably benign
R5918:Nbeal1	UTSW	1	60,307,051 (GRCm39)	missense	possibly damaging	0.90
R5923:Nbeal1	UTSW	1	60,287,554 (GRCm39)	missense	probably damaging	1.00
R6066:Nbeal1	UTSW	1	60,287,564 (GRCm39)	missense	probably benign	0.29
R6091:Nbeal1	UTSW	1	60,220,715 (GRCm39)	start gained	probably benign
R6113:Nbeal1	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
R6143:Nbeal1	UTSW	1	60,290,466 (GRCm39)	missense	possibly damaging	0.81
R6194:Nbeal1	UTSW	1	60,296,643 (GRCm39)	missense	possibly damaging	0.80
R6197:Nbeal1	UTSW	1	60,261,287 (GRCm39)	missense	probably damaging	0.99
R6228:Nbeal1	UTSW	1	60,335,083 (GRCm39)	missense	probably benign	0.00
R6229:Nbeal1	UTSW	1	60,287,524 (GRCm39)	missense	possibly damaging	0.88
R6309:Nbeal1	UTSW	1	60,277,878 (GRCm39)	missense	probably benign
R6457:Nbeal1	UTSW	1	60,292,633 (GRCm39)	missense	probably benign	0.31
R6489:Nbeal1	UTSW	1	60,370,101 (GRCm39)	missense	possibly damaging	0.89
R6845:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R7021:Nbeal1	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
R7033:Nbeal1	UTSW	1	60,350,106 (GRCm39)	missense	probably damaging	1.00
R7144:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7145:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7146:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7157:Nbeal1	UTSW	1	60,299,793 (GRCm39)	nonsense	probably null
R7157:Nbeal1	UTSW	1	60,276,317 (GRCm39)	missense	probably damaging	1.00
R7209:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7210:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7211:Nbeal1	UTSW	1	60,240,110 (GRCm39)	missense	probably damaging	1.00
R7212:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7213:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7214:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7283:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7285:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7287:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7296:Nbeal1	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
R7312:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7313:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7329:Nbeal1	UTSW	1	60,256,355 (GRCm39)	missense	probably benign	0.39
R7380:Nbeal1	UTSW	1	60,283,969 (GRCm39)	missense	probably damaging	1.00
R7414:Nbeal1	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
R7477:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R7507:Nbeal1	UTSW	1	60,274,626 (GRCm39)	missense	probably damaging	1.00
R7642:Nbeal1	UTSW	1	60,316,386 (GRCm39)	missense	probably benign	0.31
R7678:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7689:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7728:Nbeal1	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
R7757:Nbeal1	UTSW	1	60,296,609 (GRCm39)	missense	probably damaging	0.97
R7761:Nbeal1	UTSW	1	60,358,500 (GRCm39)	missense	probably benign	0.00
R7813:Nbeal1	UTSW	1	60,331,048 (GRCm39)	missense	probably damaging	1.00
R7829:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7891:Nbeal1	UTSW	1	60,299,591 (GRCm39)	missense	probably benign
R7902:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R8022:Nbeal1	UTSW	1	60,299,431 (GRCm39)	nonsense	probably null
R8053:Nbeal1	UTSW	1	60,318,954 (GRCm39)	missense	probably damaging	0.98
R8169:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8170:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8178:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8182:Nbeal1	UTSW	1	60,239,292 (GRCm39)	missense	probably benign	0.00
R8186:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8187:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8193:Nbeal1	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
R8209:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8226:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8549:Nbeal1	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
R8560:Nbeal1	UTSW	1	60,274,316 (GRCm39)	missense	probably benign	0.38
R8769:Nbeal1	UTSW	1	60,274,370 (GRCm39)	missense	probably damaging	0.99
R8771:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R8952:Nbeal1	UTSW	1	60,299,459 (GRCm39)	missense	probably benign	0.01
R9014:Nbeal1	UTSW	1	60,329,118 (GRCm39)	missense	probably damaging	1.00
R9056:Nbeal1	UTSW	1	60,317,885 (GRCm39)	missense	probably damaging	1.00
R9091:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9138:Nbeal1	UTSW	1	60,286,904 (GRCm39)	nonsense	probably null
R9168:Nbeal1	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
R9200:Nbeal1	UTSW	1	60,320,425 (GRCm39)	missense	probably damaging	1.00
R9205:Nbeal1	UTSW	1	60,317,839 (GRCm39)	missense	probably damaging	1.00
R9270:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9322:Nbeal1	UTSW	1	60,297,818 (GRCm39)	missense	possibly damaging	0.91
R9405:Nbeal1	UTSW	1	60,349,424 (GRCm39)	missense	probably damaging	1.00
R9554:Nbeal1	UTSW	1	60,290,287 (GRCm39)	nonsense	probably null
R9557:Nbeal1	UTSW	1	60,274,509 (GRCm39)	missense	probably benign
R9560:Nbeal1	UTSW	1	60,368,544 (GRCm39)	missense	probably damaging	1.00
R9641:Nbeal1	UTSW	1	60,350,247 (GRCm39)	missense	probably damaging	1.00
R9784:Nbeal1	UTSW	1	60,299,741 (GRCm39)	nonsense	probably null
X0022:Nbeal1	UTSW	1	60,316,391 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AAGTCTCTCGGAGCTAGGGTTG -3'
(R):5'- GCTTGTAGCCAACATGAACAACTC -3'

Sequencing Primer
(F):5'- TGAGTGCTGGGCCTAAACTC -3'
(R):5'- TAGCCAACATGAACAACTCAATTTAG -3'

Posted On

2021-03-08