Mutagenetix > Incidental Mutation

Incidental Mutation 'R8753:Nbea'

663959

Institutional Source

Beutler Lab

Gene Symbol

Nbea

Ensembl Gene

ENSMUSG00000027799

Gene Name

neurobeachin

Synonyms

MMRRC Submission

068619-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R8753 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

55532616-56091122 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 55534329 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Cysteine at position 2936 (Y2936C)

Ref Sequence

ENSEMBL: ENSMUSP00000029374 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000029374]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000029374
AA Change: Y2936C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000029374
Gene: ENSMUSG00000027799
AA Change: Y2936C

Domain	Start	End	E-Value	Type
low complexity region	19	40	N/A	INTRINSIC
Pfam:Laminin_G_3	228	393	2.8e-13	PFAM
Pfam:DUF4704	462	733	4e-113	PFAM
low complexity region	792	802	N/A	INTRINSIC
low complexity region	964	969	N/A	INTRINSIC
low complexity region	1781	1790	N/A	INTRINSIC
low complexity region	1791	1807	N/A	INTRINSIC
low complexity region	1835	1845	N/A	INTRINSIC
Pfam:DUF1088	1956	2122	3.5e-91	PFAM
Pfam:PH_BEACH	2148	2245	2.6e-32	PFAM
Beach	2276	2553	1.3e-205	SMART
WD40	2659	2696	2.12e2	SMART
WD40	2699	2742	2.22e0	SMART
WD40	2759	2798	9.21e0	SMART
WD40	2842	2880	2.88e-1	SMART
WD40	2883	2922	8.91e-1	SMART

Meta Mutation Damage Score

0.3708

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.9%

Validation Efficiency

95% (59/62)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
PHENOTYPE: Mice homozygous for a gene trapped allele or transgene insertion die shortly after birth, are cyanotic, and exhibit no response to tactile stimuli, no spontaneous movement, and impaired CNS synaptic transmission. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Gene trapped(3) Transgenic(1)

Other mutations in this stock

Total: 62 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca2	T	C	2: 25,332,706 (GRCm39)	Y1496H	probably damaging	Het
Acan	G	A	7: 78,748,516 (GRCm39)	E1096K	possibly damaging	Het
Adprhl1	T	C	8: 13,272,118 (GRCm39)	K1547E	possibly damaging	Het
Ampd2	C	A	3: 107,987,432 (GRCm39)	V134L	probably benign	Het
Arf4	T	A	14: 26,374,114 (GRCm39)		probably benign	Het
Boc	A	T	16: 44,320,775 (GRCm39)	M295K		Het
C2cd3	T	A	7: 100,049,024 (GRCm39)		probably null	Het
Calcrl	C	G	2: 84,178,659 (GRCm39)	G223A	probably benign	Het
Calcrl	C	A	2: 84,178,661 (GRCm39)	M222I	probably benign	Het
Ccdc88b	T	C	19: 6,833,213 (GRCm39)	E278G	probably damaging	Het
Ccz1	A	G	5: 143,925,050 (GRCm39)	C469R	probably benign	Het
Cdc40	C	T	10: 40,717,480 (GRCm39)	D404N	probably damaging	Het
Clpx	G	A	9: 65,223,958 (GRCm39)	G251S	probably damaging	Het
Col6a3	C	G	1: 90,695,328 (GRCm39)		probably benign	Het
Cpox	T	A	16: 58,498,391 (GRCm39)	M408K	probably damaging	Het
Crybb3	A	G	5: 113,226,247 (GRCm39)		probably null	Het
Cubn	A	T	2: 13,313,377 (GRCm39)	C3064*	probably null	Het
Cxcl3	CCTGCTGCTGCTGCTG	CCTGCTGCTGCTG	5: 90,934,071 (GRCm39)		probably benign	Het
Cyp4a31	A	T	4: 115,432,158 (GRCm39)	S432C	probably benign	Het
Ddias	A	T	7: 92,508,668 (GRCm39)	F416I	probably damaging	Het
Dlat	G	T	9: 50,560,967 (GRCm39)	A360E	probably damaging	Het
Dnttip2	A	G	3: 122,074,398 (GRCm39)	T612A	probably damaging	Het
Fnip1	A	G	11: 54,400,867 (GRCm39)	T1089A	probably damaging	Het
Gm12117	A	T	11: 33,225,953 (GRCm39)	L128M	probably benign	Het
Gtf2h5	C	CA	17: 6,134,833 (GRCm39)		probably null	Het
Ibtk	T	C	9: 85,610,819 (GRCm39)	T285A	probably benign	Het
Ifi206	A	T	1: 173,301,223 (GRCm39)	N818K	unknown	Het
Itga10	T	G	3: 96,558,471 (GRCm39)	L305R	probably damaging	Het
Khnyn	T	C	14: 56,125,223 (GRCm39)	Y461H	possibly damaging	Het
Macroh2a2	T	C	10: 61,585,113 (GRCm39)	D177G	possibly damaging	Het
Mbtps1	T	C	8: 120,235,601 (GRCm39)	S1026G	possibly damaging	Het
Msantd4	A	G	9: 4,385,013 (GRCm39)	E246G	probably damaging	Het
N4bp1	T	C	8: 87,575,085 (GRCm39)	I737V	probably damaging	Het
Nav2	T	G	7: 49,102,320 (GRCm39)	S373A	probably benign	Het
Nbeal1	A	T	1: 60,307,542 (GRCm39)	I1685F	probably damaging	Het
Nt5c3	C	G	6: 56,860,677 (GRCm39)	G293R	probably damaging	Het
Or4f14c	A	T	2: 111,940,802 (GRCm39)	V265E	probably benign	Het
Or52z1	T	A	7: 103,436,567 (GRCm39)	I306F	probably benign	Het
Pcnx2	A	T	8: 126,613,999 (GRCm39)	V484E	probably benign	Het
Pcsk5	C	T	19: 17,446,408 (GRCm39)	R1195Q	probably benign	Het
Perm1	TGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCT	TGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCTGAGCCTGACACGGCTTTGTCTACACCCGCCTCT	4: 156,302,525 (GRCm39)		probably benign	Het
Pitpnm3	A	G	11: 71,942,704 (GRCm39)	V861A	probably benign	Het
Pkd1	A	G	17: 24,793,176 (GRCm39)	Y1621C	probably damaging	Het
Polr3a	C	A	14: 24,513,702 (GRCm39)	E846*	probably null	Het
Polr3e	T	C	7: 120,539,540 (GRCm39)	V455A	possibly damaging	Het
Prr5l	C	T	2: 101,571,723 (GRCm39)	G118D	probably damaging	Het
Pygl	G	T	12: 70,242,400 (GRCm39)	N685K	probably damaging	Het
Rfx8	A	G	1: 39,757,600 (GRCm39)	V56A	probably damaging	Het
Sbf1	T	C	15: 89,179,662 (GRCm39)	D1341G	probably benign	Het
Selenon	T	C	4: 134,275,330 (GRCm39)	T123A	probably benign	Het
Slc23a1	T	G	18: 35,752,631 (GRCm39)	K549Q	probably benign	Het
Slc7a13	T	C	4: 19,841,443 (GRCm39)	F430S	probably damaging	Het
Smarcc2	G	A	10: 128,319,070 (GRCm39)	V707M	probably damaging	Het
St18	A	G	1: 6,916,015 (GRCm39)	S887G	probably damaging	Het
T2	T	C	17: 8,615,477 (GRCm39)		probably benign	Het
Tbc1d16	A	G	11: 119,101,492 (GRCm39)	L6P	probably damaging	Het
Tcf7l2	T	C	19: 55,920,195 (GRCm39)	L576P	possibly damaging	Het
Tnr	A	G	1: 159,677,936 (GRCm39)	D107G	probably benign	Het
Trpv1	G	T	11: 73,135,082 (GRCm39)	K426N	probably damaging	Het
Vmn1r15	A	T	6: 57,235,895 (GRCm39)	L254F	probably benign	Het
Vmn1r219	A	T	13: 23,347,191 (GRCm39)	I127F	probably damaging	Het
Zc3h14	A	T	12: 98,724,831 (GRCm39)	E164D	probably benign	Het

Other mutations in Nbea

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00540:Nbea	APN	3	55,535,914 (GRCm39)	missense	probably damaging	1.00
IGL00541:Nbea	APN	3	55,875,510 (GRCm39)	missense	probably benign	0.02
IGL00584:Nbea	APN	3	55,989,869 (GRCm39)	missense	probably damaging	0.98
IGL00648:Nbea	APN	3	55,916,681 (GRCm39)	missense	probably damaging	0.98
IGL00785:Nbea	APN	3	55,862,814 (GRCm39)	missense	probably benign
IGL00899:Nbea	APN	3	55,550,266 (GRCm39)	missense	probably benign	0.32
IGL00955:Nbea	APN	3	55,912,893 (GRCm39)	missense	possibly damaging	0.45
IGL01296:Nbea	APN	3	55,938,957 (GRCm39)	missense	probably benign	0.04
IGL01299:Nbea	APN	3	55,598,315 (GRCm39)	missense	probably damaging	1.00
IGL01393:Nbea	APN	3	55,912,729 (GRCm39)	missense	probably benign	0.02
IGL01550:Nbea	APN	3	55,712,669 (GRCm39)	missense	possibly damaging	0.93
IGL02023:Nbea	APN	3	55,588,437 (GRCm39)	missense	probably damaging	1.00
IGL02034:Nbea	APN	3	55,875,577 (GRCm39)	missense	probably damaging	1.00
IGL02061:Nbea	APN	3	55,625,308 (GRCm39)	missense	possibly damaging	0.54
IGL02082:Nbea	APN	3	55,875,588 (GRCm39)	missense	possibly damaging	0.88
IGL02113:Nbea	APN	3	55,899,913 (GRCm39)	missense	probably benign
IGL02188:Nbea	APN	3	55,891,258 (GRCm39)	missense	probably benign	0.00
IGL02319:Nbea	APN	3	55,893,159 (GRCm39)	missense	probably damaging	1.00
IGL02406:Nbea	APN	3	55,993,687 (GRCm39)	missense	probably benign	0.02
IGL02494:Nbea	APN	3	55,712,772 (GRCm39)	missense	probably benign	0.02
IGL02550:Nbea	APN	3	55,926,835 (GRCm39)	missense	probably damaging	0.98
IGL02706:Nbea	APN	3	55,944,699 (GRCm39)	missense	probably damaging	1.00
IGL02718:Nbea	APN	3	55,539,483 (GRCm39)	nonsense	probably null
IGL02822:Nbea	APN	3	55,926,868 (GRCm39)	missense	possibly damaging	0.93
IGL02885:Nbea	APN	3	55,539,407 (GRCm39)	missense	probably benign	0.01
IGL03000:Nbea	APN	3	55,912,048 (GRCm39)	missense	possibly damaging	0.94
IGL03081:Nbea	APN	3	55,987,339 (GRCm39)	missense	probably damaging	1.00
IGL03091:Nbea	APN	3	55,992,725 (GRCm39)	missense	probably damaging	1.00
IGL03368:Nbea	APN	3	55,987,351 (GRCm39)	missense	probably damaging	0.98
Neches	UTSW	3	55,860,455 (GRCm39)	critical splice donor site	probably null
scotland	UTSW	3	55,534,329 (GRCm39)	missense	probably damaging	1.00
Wales	UTSW	3	55,998,540 (GRCm39)	missense	probably damaging	1.00
FR4340:Nbea	UTSW	3	55,916,633 (GRCm39)	critical splice donor site	probably benign
G4846:Nbea	UTSW	3	55,994,918 (GRCm39)	missense	probably damaging	0.98
IGL02835:Nbea	UTSW	3	55,625,290 (GRCm39)	missense	possibly damaging	0.88
LCD18:Nbea	UTSW	3	55,608,948 (GRCm39)	intron	probably benign
R0087:Nbea	UTSW	3	55,998,444 (GRCm39)	missense	possibly damaging	0.92
R0220:Nbea	UTSW	3	55,912,724 (GRCm39)	missense	probably benign	0.30
R0324:Nbea	UTSW	3	55,965,369 (GRCm39)	critical splice donor site	probably null
R0330:Nbea	UTSW	3	55,550,238 (GRCm39)	missense	probably benign	0.27
R0391:Nbea	UTSW	3	55,944,698 (GRCm39)	missense	probably damaging	1.00
R0394:Nbea	UTSW	3	55,937,328 (GRCm39)	missense	probably damaging	1.00
R0419:Nbea	UTSW	3	55,726,715 (GRCm39)	missense	probably benign	0.05
R0503:Nbea	UTSW	3	55,550,257 (GRCm39)	missense	possibly damaging	0.79
R0521:Nbea	UTSW	3	55,915,689 (GRCm39)	missense	probably damaging	1.00
R0595:Nbea	UTSW	3	55,535,917 (GRCm39)	missense	probably benign	0.18
R0894:Nbea	UTSW	3	55,916,761 (GRCm39)	missense	possibly damaging	0.89
R1072:Nbea	UTSW	3	55,993,617 (GRCm39)	missense	possibly damaging	0.94
R1125:Nbea	UTSW	3	55,764,427 (GRCm39)	nonsense	probably null
R1169:Nbea	UTSW	3	55,875,744 (GRCm39)	missense	probably benign	0.00
R1241:Nbea	UTSW	3	55,965,461 (GRCm39)	missense	probably damaging	1.00
R1269:Nbea	UTSW	3	55,912,202 (GRCm39)	missense	probably benign	0.05
R1406:Nbea	UTSW	3	55,944,702 (GRCm39)	missense	probably benign	0.00
R1406:Nbea	UTSW	3	55,944,702 (GRCm39)	missense	probably benign	0.00
R1457:Nbea	UTSW	3	55,992,748 (GRCm39)	missense	probably damaging	1.00
R1482:Nbea	UTSW	3	55,987,414 (GRCm39)	missense	probably damaging	1.00
R1483:Nbea	UTSW	3	55,910,211 (GRCm39)	missense	probably benign	0.25
R1502:Nbea	UTSW	3	55,912,310 (GRCm39)	missense	probably benign	0.03
R1544:Nbea	UTSW	3	55,966,248 (GRCm39)	missense	probably damaging	0.99
R1629:Nbea	UTSW	3	55,910,312 (GRCm39)	missense	possibly damaging	0.52
R1647:Nbea	UTSW	3	55,537,650 (GRCm39)	missense	probably damaging	0.97
R1663:Nbea	UTSW	3	55,553,407 (GRCm39)	missense	possibly damaging	0.95
R1722:Nbea	UTSW	3	55,573,116 (GRCm39)	missense	probably damaging	1.00
R1757:Nbea	UTSW	3	55,537,610 (GRCm39)	missense	possibly damaging	0.83
R1771:Nbea	UTSW	3	55,841,940 (GRCm39)	missense	probably benign	0.00
R1796:Nbea	UTSW	3	55,551,129 (GRCm39)	missense	possibly damaging	0.48
R1844:Nbea	UTSW	3	55,989,857 (GRCm39)	missense	probably damaging	0.97
R1872:Nbea	UTSW	3	55,550,310 (GRCm39)	missense	probably benign	0.12
R1938:Nbea	UTSW	3	55,992,743 (GRCm39)	missense	probably damaging	1.00
R1940:Nbea	UTSW	3	55,860,521 (GRCm39)	missense	possibly damaging	0.78
R2062:Nbea	UTSW	3	55,993,578 (GRCm39)	splice site	probably benign
R2066:Nbea	UTSW	3	55,875,567 (GRCm39)	missense	probably damaging	1.00
R2097:Nbea	UTSW	3	55,630,638 (GRCm39)	missense	probably damaging	0.96
R2181:Nbea	UTSW	3	55,937,360 (GRCm39)	missense	possibly damaging	0.92
R2274:Nbea	UTSW	3	55,895,506 (GRCm39)	splice site	probably null
R2345:Nbea	UTSW	3	55,992,700 (GRCm39)	missense	probably damaging	1.00
R2423:Nbea	UTSW	3	55,992,727 (GRCm39)	missense	probably damaging	1.00
R2434:Nbea	UTSW	3	55,554,881 (GRCm39)	missense	possibly damaging	0.91
R2880:Nbea	UTSW	3	55,554,779 (GRCm39)	missense	probably benign	0.04
R2881:Nbea	UTSW	3	55,554,779 (GRCm39)	missense	probably benign	0.04
R2940:Nbea	UTSW	3	55,842,045 (GRCm39)	missense	probably benign	0.24
R3500:Nbea	UTSW	3	55,588,431 (GRCm39)	missense	possibly damaging	0.88
R3765:Nbea	UTSW	3	55,912,970 (GRCm39)	missense	probably damaging	1.00
R3790:Nbea	UTSW	3	55,912,450 (GRCm39)	missense	probably benign
R3808:Nbea	UTSW	3	55,625,269 (GRCm39)	missense	probably benign	0.02
R3845:Nbea	UTSW	3	55,993,713 (GRCm39)	splice site	probably benign
R4182:Nbea	UTSW	3	55,915,848 (GRCm39)	missense	probably damaging	0.99
R4385:Nbea	UTSW	3	55,908,059 (GRCm39)	missense	possibly damaging	0.77
R4419:Nbea	UTSW	3	55,917,021 (GRCm39)	missense	probably damaging	1.00
R4426:Nbea	UTSW	3	55,989,800 (GRCm39)	missense	probably damaging	0.98
R4451:Nbea	UTSW	3	55,899,753 (GRCm39)	critical splice donor site	probably null
R4456:Nbea	UTSW	3	55,551,205 (GRCm39)	missense	probably benign	0.00
R4604:Nbea	UTSW	3	55,631,069 (GRCm39)	missense	probably benign	0.18
R4687:Nbea	UTSW	3	55,965,486 (GRCm39)	missense	probably damaging	1.00
R4758:Nbea	UTSW	3	55,912,824 (GRCm39)	missense	probably benign
R4840:Nbea	UTSW	3	55,618,091 (GRCm39)	missense	probably benign	0.37
R4888:Nbea	UTSW	3	55,912,776 (GRCm39)	missense	possibly damaging	0.61
R4954:Nbea	UTSW	3	55,943,379 (GRCm39)	missense	probably damaging	1.00
R4972:Nbea	UTSW	3	55,992,667 (GRCm39)	missense	probably damaging	0.99
R4980:Nbea	UTSW	3	55,860,466 (GRCm39)	missense	probably benign	0.00
R4980:Nbea	UTSW	3	55,554,772 (GRCm39)	splice site	probably null
R5104:Nbea	UTSW	3	55,987,348 (GRCm39)	missense	probably damaging	1.00
R5139:Nbea	UTSW	3	55,534,384 (GRCm39)	missense	possibly damaging	0.90
R5166:Nbea	UTSW	3	55,926,874 (GRCm39)	missense	probably damaging	1.00
R5347:Nbea	UTSW	3	55,948,297 (GRCm39)	missense	probably damaging	1.00
R5350:Nbea	UTSW	3	55,926,845 (GRCm39)	missense	probably damaging	1.00
R5418:Nbea	UTSW	3	55,553,410 (GRCm39)	missense	possibly damaging	0.86
R5586:Nbea	UTSW	3	55,539,392 (GRCm39)	missense	probably benign	0.08
R5627:Nbea	UTSW	3	55,899,766 (GRCm39)	missense	probably damaging	1.00
R5683:Nbea	UTSW	3	55,536,007 (GRCm39)	missense	possibly damaging	0.53
R5765:Nbea	UTSW	3	55,912,719 (GRCm39)	missense	probably benign	0.15
R5853:Nbea	UTSW	3	55,899,822 (GRCm39)	missense	probably damaging	1.00
R5858:Nbea	UTSW	3	55,860,455 (GRCm39)	critical splice donor site	probably null
R5955:Nbea	UTSW	3	55,588,404 (GRCm39)	missense	probably benign	0.00
R5976:Nbea	UTSW	3	55,761,268 (GRCm39)	missense	probably benign	0.30
R6039:Nbea	UTSW	3	55,912,538 (GRCm39)	missense	probably benign	0.00
R6039:Nbea	UTSW	3	55,912,538 (GRCm39)	missense	probably benign	0.00
R6043:Nbea	UTSW	3	55,693,896 (GRCm39)	missense	probably benign	0.32
R6122:Nbea	UTSW	3	55,937,317 (GRCm39)	missense	probably damaging	1.00
R6218:Nbea	UTSW	3	55,535,905 (GRCm39)	missense	probably damaging	0.97
R6331:Nbea	UTSW	3	55,908,037 (GRCm39)	missense	possibly damaging	0.94
R6334:Nbea	UTSW	3	55,944,570 (GRCm39)	missense	probably damaging	1.00
R6393:Nbea	UTSW	3	55,998,540 (GRCm39)	missense	probably damaging	1.00
R6411:Nbea	UTSW	3	55,712,778 (GRCm39)	missense	probably benign	0.01
R6457:Nbea	UTSW	3	55,907,990 (GRCm39)	missense	probably damaging	1.00
R6476:Nbea	UTSW	3	55,912,227 (GRCm39)	missense	probably benign	0.00
R6488:Nbea	UTSW	3	55,625,264 (GRCm39)	missense	probably damaging	0.99
R6700:Nbea	UTSW	3	55,989,869 (GRCm39)	missense	possibly damaging	0.89
R6702:Nbea	UTSW	3	55,912,923 (GRCm39)	missense	probably benign	0.06
R6752:Nbea	UTSW	3	55,944,640 (GRCm39)	missense	probably benign
R6752:Nbea	UTSW	3	55,875,730 (GRCm39)	missense	probably benign	0.02
R6804:Nbea	UTSW	3	55,994,874 (GRCm39)	missense	probably benign	0.37
R6901:Nbea	UTSW	3	55,926,836 (GRCm39)	missense	probably damaging	1.00
R6933:Nbea	UTSW	3	55,631,031 (GRCm39)	missense	possibly damaging	0.63
R7124:Nbea	UTSW	3	55,899,865 (GRCm39)	missense	probably damaging	1.00
R7211:Nbea	UTSW	3	55,912,322 (GRCm39)	missense	probably benign	0.05
R7308:Nbea	UTSW	3	55,998,452 (GRCm39)	missense	probably damaging	1.00
R7405:Nbea	UTSW	3	55,712,687 (GRCm39)	missense	possibly damaging	0.94
R7669:Nbea	UTSW	3	55,625,200 (GRCm39)	missense	probably damaging	1.00
R7762:Nbea	UTSW	3	55,557,126 (GRCm39)	missense	probably damaging	1.00
R7833:Nbea	UTSW	3	55,910,218 (GRCm39)	missense	probably damaging	1.00
R7885:Nbea	UTSW	3	55,573,110 (GRCm39)	missense	probably damaging	0.97
R7935:Nbea	UTSW	3	55,966,086 (GRCm39)	missense	probably damaging	1.00
R8050:Nbea	UTSW	3	55,895,402 (GRCm39)	missense	probably damaging	0.99
R8108:Nbea	UTSW	3	55,726,736 (GRCm39)	missense	probably benign	0.11
R8290:Nbea	UTSW	3	55,966,056 (GRCm39)	nonsense	probably null
R8314:Nbea	UTSW	3	55,916,672 (GRCm39)	missense	probably damaging	0.99
R8321:Nbea	UTSW	3	56,090,518 (GRCm39)	missense	possibly damaging	0.86
R8376:Nbea	UTSW	3	55,551,076 (GRCm39)	missense	possibly damaging	0.79
R8410:Nbea	UTSW	3	55,944,684 (GRCm39)	missense	probably damaging	1.00
R8556:Nbea	UTSW	3	55,554,807 (GRCm39)	missense	probably benign	0.25
R8844:Nbea	UTSW	3	55,998,415 (GRCm39)	missense	probably damaging	0.97
R8884:Nbea	UTSW	3	55,712,720 (GRCm39)	missense	probably benign	0.00
R8886:Nbea	UTSW	3	55,966,148 (GRCm39)	missense	probably damaging	1.00
R8890:Nbea	UTSW	3	55,926,784 (GRCm39)	splice site	probably benign
R9004:Nbea	UTSW	3	55,910,359 (GRCm39)	missense	probably benign	0.01
R9022:Nbea	UTSW	3	55,551,110 (GRCm39)	missense	possibly damaging	0.79
R9080:Nbea	UTSW	3	55,912,516 (GRCm39)	nonsense	probably null
R9087:Nbea	UTSW	3	55,550,157 (GRCm39)	critical splice donor site	probably null
R9104:Nbea	UTSW	3	55,862,809 (GRCm39)	missense	probably benign
R9165:Nbea	UTSW	3	55,912,289 (GRCm39)	missense	probably benign	0.15
R9219:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9221:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9222:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9260:Nbea	UTSW	3	55,891,233 (GRCm39)	missense	possibly damaging	0.50
R9263:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9265:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9294:Nbea	UTSW	3	55,998,513 (GRCm39)	missense	probably benign	0.00
R9360:Nbea	UTSW	3	55,943,319 (GRCm39)	missense	possibly damaging	0.96
R9387:Nbea	UTSW	3	55,898,460 (GRCm39)	missense	probably benign	0.12
R9428:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9435:Nbea	UTSW	3	55,943,309 (GRCm39)	missense	possibly damaging	0.63
R9507:Nbea	UTSW	3	55,573,011 (GRCm39)	missense	probably damaging	1.00
R9514:Nbea	UTSW	3	55,937,366 (GRCm39)	missense	probably damaging	1.00
R9516:Nbea	UTSW	3	55,937,366 (GRCm39)	missense	probably damaging	1.00
R9674:Nbea	UTSW	3	55,966,183 (GRCm39)	missense	probably damaging	1.00
R9688:Nbea	UTSW	3	55,557,165 (GRCm39)	missense	probably benign	0.42
R9709:Nbea	UTSW	3	55,693,879 (GRCm39)	nonsense	probably null
RF051:Nbea	UTSW	3	55,916,633 (GRCm39)	critical splice donor site	probably benign
X0018:Nbea	UTSW	3	55,943,469 (GRCm39)	missense	probably benign	0.39
Z1088:Nbea	UTSW	3	55,630,584 (GRCm39)	missense	probably benign	0.34
Z1177:Nbea	UTSW	3	55,938,971 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- ATTACCAAAACGGCTCCTAATTCAG -3'
(R):5'- TCTGAGATAAGGCCGGTGTC -3'

Sequencing Primer
(F):5'- CTGGTGTTCAGTCCTGGAAAAAC -3'
(R):5'- TGTCAGCATAAAGTGGCAAGTTC -3'

Posted On

2021-03-08