Incidental Mutation 'R8768:Phrf1'
| ID |
664232 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phrf1
|
| Ensembl Gene |
ENSMUSG00000038611 |
| Gene Name |
PHD and ring finger domains 1 |
| Synonyms |
|
| MMRRC Submission |
068623-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8768 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
140808697-140842663 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 140838651 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 615
(F615L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113195
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026571]
[ENSMUST00000097952]
[ENSMUST00000106023]
[ENSMUST00000106027]
[ENSMUST00000122143]
[ENSMUST00000132540]
[ENSMUST00000155123]
[ENSMUST00000209899]
|
| AlphaFold |
A6H619 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026571
|
| SMART Domains |
Protein: ENSMUSP00000026571
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
5 |
127 |
1.13e-54 |
SMART |
|
IRF-3
|
240 |
420 |
1.38e-63 |
SMART |
|
low complexity region
|
425 |
442 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000097952
|
| SMART Domains |
Protein: ENSMUSP00000095565
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
5 |
127 |
1.13e-54 |
SMART |
|
IRF-3
|
209 |
389 |
1.38e-63 |
SMART |
|
low complexity region
|
394 |
411 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106023
|
| SMART Domains |
Protein: ENSMUSP00000101644
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
5 |
127 |
1.13e-54 |
SMART |
|
IRF-3
|
208 |
388 |
1.38e-63 |
SMART |
|
low complexity region
|
393 |
410 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000106027
AA Change: F774L
|
| SMART Domains |
Protein: ENSMUSP00000101648
Gene: ENSMUSG00000038611
AA Change: F774L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
24 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
39 |
70 |
N/A |
INTRINSIC |
|
RING
|
109 |
149 |
3.78e-5 |
SMART |
|
C1
|
173 |
229 |
7.05e-2 |
SMART |
|
PHD
|
187 |
233 |
1.77e-14 |
SMART |
|
RING
|
188 |
232 |
3.17e0 |
SMART |
|
low complexity region
|
332 |
369 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
505 |
N/A |
INTRINSIC |
|
low complexity region
|
507 |
522 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
728 |
N/A |
INTRINSIC |
|
low complexity region
|
831 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
891 |
902 |
N/A |
INTRINSIC |
|
low complexity region
|
944 |
955 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
976 |
N/A |
INTRINSIC |
|
low complexity region
|
999 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1027 |
1043 |
N/A |
INTRINSIC |
|
low complexity region
|
1051 |
1090 |
N/A |
INTRINSIC |
|
low complexity region
|
1094 |
1151 |
N/A |
INTRINSIC |
|
low complexity region
|
1160 |
1173 |
N/A |
INTRINSIC |
|
low complexity region
|
1217 |
1241 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1261 |
N/A |
INTRINSIC |
|
low complexity region
|
1288 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1308 |
1319 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1426 |
1441 |
N/A |
INTRINSIC |
|
low complexity region
|
1575 |
1592 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
1593 |
1636 |
4e-14 |
BLAST |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000122143
AA Change: F615L
|
| SMART Domains |
Protein: ENSMUSP00000113195
Gene: ENSMUSG00000038611
AA Change: F615L
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
14 |
70 |
7.05e-2 |
SMART |
|
PHD
|
28 |
74 |
1.77e-14 |
SMART |
|
low complexity region
|
173 |
210 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
346 |
N/A |
INTRINSIC |
|
low complexity region
|
348 |
363 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
672 |
698 |
N/A |
INTRINSIC |
|
low complexity region
|
732 |
743 |
N/A |
INTRINSIC |
|
low complexity region
|
785 |
796 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
840 |
861 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
884 |
N/A |
INTRINSIC |
|
low complexity region
|
892 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
935 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1001 |
1014 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1082 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1102 |
N/A |
INTRINSIC |
|
low complexity region
|
1129 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1149 |
1160 |
N/A |
INTRINSIC |
|
low complexity region
|
1200 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1267 |
1282 |
N/A |
INTRINSIC |
|
low complexity region
|
1416 |
1433 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
1434 |
1477 |
4e-14 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123525
|
| SMART Domains |
Protein: ENSMUSP00000121026
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
1 |
69 |
6.35e-3 |
SMART |
|
IRF-3
|
77 |
251 |
2.62e-55 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130687
|
| SMART Domains |
Protein: ENSMUSP00000123351
Gene: ENSMUSG00000038611
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
33 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
100 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
241 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
242 |
285 |
5e-15 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132540
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000142572
|
| SMART Domains |
Protein: ENSMUSP00000117393
Gene: ENSMUSG00000038611
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
41 |
52 |
N/A |
INTRINSIC |
|
low complexity region
|
75 |
96 |
N/A |
INTRINSIC |
|
low complexity region
|
103 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
166 |
N/A |
INTRINSIC |
|
low complexity region
|
170 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
249 |
N/A |
INTRINSIC |
|
low complexity region
|
293 |
317 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
337 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
384 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
452 |
N/A |
INTRINSIC |
|
low complexity region
|
666 |
683 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
684 |
727 |
3e-14 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155123
|
| SMART Domains |
Protein: ENSMUSP00000120759
Gene: ENSMUSG00000038611
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
24 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
39 |
70 |
N/A |
INTRINSIC |
|
RING
|
109 |
149 |
3.78e-5 |
SMART |
|
Blast:C1
|
165 |
209 |
2e-17 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000209899
|
| Meta Mutation Damage Score |
0.0725 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
99% (76/77) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actr1b |
A |
T |
1: 36,740,588 (GRCm39) |
C222S |
probably benign |
Het |
| Actrt3 |
T |
G |
3: 30,651,992 (GRCm39) |
R367S |
probably damaging |
Het |
| Alg1 |
T |
C |
16: 5,060,416 (GRCm39) |
V379A |
probably damaging |
Het |
| Ankrd36 |
A |
G |
11: 5,593,763 (GRCm39) |
E456G |
probably benign |
Het |
| Arhgef33 |
G |
T |
17: 80,681,148 (GRCm39) |
A763S |
possibly damaging |
Het |
| Armc5 |
T |
G |
7: 127,841,783 (GRCm39) |
V597G |
probably benign |
Het |
| Asb10 |
G |
T |
5: 24,738,690 (GRCm39) |
R456S |
probably damaging |
Het |
| Asph |
A |
G |
4: 9,453,417 (GRCm39) |
F702L |
probably damaging |
Het |
| Atf7 |
T |
A |
15: 102,449,324 (GRCm39) |
T326S |
probably benign |
Het |
| Atxn7l2 |
T |
C |
3: 108,114,250 (GRCm39) |
N171D |
probably benign |
Het |
| BC049715 |
T |
A |
6: 136,816,979 (GRCm39) |
M73K |
possibly damaging |
Het |
| C2cd6 |
A |
G |
1: 59,105,312 (GRCm39) |
V322A |
probably benign |
Het |
| Cadps2 |
A |
C |
6: 23,382,938 (GRCm39) |
C807W |
probably damaging |
Het |
| Ccdc57 |
C |
T |
11: 120,788,788 (GRCm39) |
R353H |
probably benign |
Het |
| Ccdc89 |
T |
C |
7: 90,075,793 (GRCm39) |
M1T |
probably null |
Het |
| Cntn1 |
G |
A |
15: 92,132,347 (GRCm39) |
V148M |
probably damaging |
Het |
| Csmd3 |
T |
A |
15: 47,561,572 (GRCm39) |
I1335F |
|
Het |
| Dap3 |
A |
G |
3: 88,834,334 (GRCm39) |
M294T |
probably damaging |
Het |
| Dbh |
A |
G |
2: 27,060,328 (GRCm39) |
D168G |
probably benign |
Het |
| Dchs2 |
C |
A |
3: 83,253,592 (GRCm39) |
A2334E |
probably benign |
Het |
| Dcun1d4 |
T |
A |
5: 73,678,310 (GRCm39) |
Y102N |
probably benign |
Het |
| Dhtkd1 |
T |
C |
2: 5,903,533 (GRCm39) |
T918A |
probably benign |
Het |
| Dmgdh |
C |
T |
13: 93,825,118 (GRCm39) |
T147I |
possibly damaging |
Het |
| Dmxl2 |
T |
G |
9: 54,301,105 (GRCm39) |
K2335N |
possibly damaging |
Het |
| Efna5 |
T |
C |
17: 63,188,125 (GRCm39) |
M1V |
probably null |
Het |
| Fpr-rs3 |
T |
C |
17: 20,844,944 (GRCm39) |
N66D |
probably damaging |
Het |
| Gas2l2 |
C |
A |
11: 83,313,999 (GRCm39) |
A438S |
probably benign |
Het |
| Hivep3 |
T |
C |
4: 119,989,521 (GRCm39) |
S1991P |
probably damaging |
Het |
| Hsp90b1 |
A |
T |
10: 86,541,169 (GRCm39) |
|
probably null |
Het |
| Iars1 |
T |
A |
13: 49,878,102 (GRCm39) |
N875K |
probably damaging |
Het |
| Jag1 |
A |
C |
2: 136,943,521 (GRCm39) |
M225R |
possibly damaging |
Het |
| Jag1 |
T |
C |
2: 136,932,708 (GRCm39) |
|
probably benign |
Het |
| Kcnn2 |
C |
T |
18: 45,692,502 (GRCm39) |
S26L |
possibly damaging |
Het |
| Kctd2 |
T |
C |
11: 115,311,279 (GRCm39) |
S96P |
probably damaging |
Het |
| Klhl25 |
A |
G |
7: 75,516,359 (GRCm39) |
N422D |
probably damaging |
Het |
| Lhx8 |
A |
T |
3: 154,027,886 (GRCm39) |
V222E |
possibly damaging |
Het |
| Lrig1 |
A |
T |
6: 94,631,840 (GRCm39) |
V120D |
possibly damaging |
Het |
| Manba |
T |
A |
3: 135,256,995 (GRCm39) |
S553T |
probably damaging |
Het |
| Mllt10 |
T |
A |
2: 18,167,583 (GRCm39) |
S503T |
probably damaging |
Het |
| Nxpe4 |
A |
G |
9: 48,304,050 (GRCm39) |
N46D |
probably benign |
Het |
| Or1l4b |
C |
T |
2: 37,037,016 (GRCm39) |
S264L |
probably benign |
Het |
| Or8b50 |
A |
C |
9: 38,518,441 (GRCm39) |
K227Q |
probably benign |
Het |
| Pdzd2 |
C |
T |
15: 12,437,252 (GRCm39) |
E450K |
probably damaging |
Het |
| Plch2 |
C |
A |
4: 155,083,324 (GRCm39) |
G538V |
probably damaging |
Het |
| Ppp2r2d |
T |
A |
7: 138,475,897 (GRCm39) |
I235N |
probably damaging |
Het |
| Prdm15 |
A |
T |
16: 97,638,888 (GRCm39) |
D57E |
probably benign |
Het |
| Psd3 |
T |
C |
8: 68,417,003 (GRCm39) |
D45G |
probably damaging |
Het |
| Ptger4 |
T |
A |
15: 5,272,138 (GRCm39) |
R185S |
probably benign |
Het |
| Ptp4a2 |
T |
A |
4: 129,740,299 (GRCm39) |
M121K |
probably damaging |
Het |
| Ptpre |
T |
G |
7: 135,283,306 (GRCm39) |
F659V |
possibly damaging |
Het |
| Rad54l2 |
T |
G |
9: 106,596,809 (GRCm39) |
D199A |
probably benign |
Het |
| Rap1gds1 |
T |
C |
3: 138,647,521 (GRCm39) |
M556V |
probably benign |
Het |
| Scaf8 |
T |
C |
17: 3,243,349 (GRCm39) |
V711A |
probably benign |
Het |
| Sesn3 |
G |
A |
9: 14,225,964 (GRCm39) |
C233Y |
probably damaging |
Het |
| Slc45a1 |
T |
A |
4: 150,714,206 (GRCm39) |
I680F |
probably damaging |
Het |
| Slco1a6 |
C |
T |
6: 142,078,897 (GRCm39) |
V133M |
probably benign |
Het |
| Syt6 |
T |
C |
3: 103,492,850 (GRCm39) |
L119P |
probably benign |
Het |
| Szt2 |
A |
C |
4: 118,226,613 (GRCm39) |
S2974R |
unknown |
Het |
| Taok1 |
A |
T |
11: 77,444,712 (GRCm39) |
H454Q |
probably damaging |
Het |
| Tbx10 |
G |
A |
19: 4,047,303 (GRCm39) |
V136M |
probably damaging |
Het |
| Tespa1 |
A |
G |
10: 130,198,027 (GRCm39) |
T350A |
probably benign |
Het |
| Tnks1bp1 |
T |
A |
2: 84,900,980 (GRCm39) |
Y1562* |
probably null |
Het |
| Trank1 |
T |
A |
9: 111,218,344 (GRCm39) |
F1908Y |
probably benign |
Het |
| Trav6d-4 |
A |
T |
14: 52,991,243 (GRCm39) |
H96L |
possibly damaging |
Het |
| Tspoap1 |
T |
C |
11: 87,669,197 (GRCm39) |
I1490T |
probably benign |
Het |
| Ttc21a |
T |
C |
9: 119,770,286 (GRCm39) |
F119S |
probably damaging |
Het |
| Ttll3 |
T |
G |
6: 113,385,949 (GRCm39) |
M594R |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,798,790 (GRCm39) |
R495* |
probably null |
Het |
| Twf1 |
A |
C |
15: 94,479,110 (GRCm39) |
L250V |
probably damaging |
Het |
| Ubr4 |
A |
T |
4: 139,149,076 (GRCm39) |
E458D |
|
Het |
| Unc50 |
T |
C |
1: 37,476,244 (GRCm39) |
F135L |
probably benign |
Het |
| Vwa3a |
T |
A |
7: 120,375,299 (GRCm39) |
I371N |
probably damaging |
Het |
| Zfp180 |
T |
C |
7: 23,805,161 (GRCm39) |
S527P |
probably damaging |
Het |
| Zfp512 |
T |
A |
5: 31,630,882 (GRCm39) |
I408N |
probably damaging |
Het |
| Zfp57 |
A |
G |
17: 37,317,077 (GRCm39) |
T52A |
probably benign |
Het |
| Zranb2 |
A |
G |
3: 157,247,327 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Phrf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00551:Phrf1
|
APN |
7 |
140,838,790 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01391:Phrf1
|
APN |
7 |
140,842,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01472:Phrf1
|
APN |
7 |
140,836,403 (GRCm39) |
splice site |
probably benign |
|
|
IGL01633:Phrf1
|
APN |
7 |
140,840,413 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL01808:Phrf1
|
APN |
7 |
140,840,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02004:Phrf1
|
APN |
7 |
140,840,246 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02138:Phrf1
|
APN |
7 |
140,839,196 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02678:Phrf1
|
APN |
7 |
140,840,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03077:Phrf1
|
APN |
7 |
140,834,881 (GRCm39) |
nonsense |
probably null |
|
|
PIT4466001:Phrf1
|
UTSW |
7 |
140,838,725 (GRCm39) |
missense |
unknown |
|
|
R0036:Phrf1
|
UTSW |
7 |
140,841,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0036:Phrf1
|
UTSW |
7 |
140,841,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Phrf1
|
UTSW |
7 |
140,823,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0358:Phrf1
|
UTSW |
7 |
140,838,217 (GRCm39) |
unclassified |
probably benign |
|
|
R0445:Phrf1
|
UTSW |
7 |
140,827,244 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R0535:Phrf1
|
UTSW |
7 |
140,839,978 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0561:Phrf1
|
UTSW |
7 |
140,834,876 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0940:Phrf1
|
UTSW |
7 |
140,834,768 (GRCm39) |
splice site |
probably benign |
|
|
R1499:Phrf1
|
UTSW |
7 |
140,836,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1511:Phrf1
|
UTSW |
7 |
140,839,714 (GRCm39) |
unclassified |
probably benign |
|
|
R1651:Phrf1
|
UTSW |
7 |
140,817,434 (GRCm39) |
missense |
probably benign |
|
|
R1691:Phrf1
|
UTSW |
7 |
140,841,787 (GRCm39) |
nonsense |
probably null |
|
|
R1778:Phrf1
|
UTSW |
7 |
140,812,369 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1851:Phrf1
|
UTSW |
7 |
140,820,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2239:Phrf1
|
UTSW |
7 |
140,817,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2857:Phrf1
|
UTSW |
7 |
140,839,593 (GRCm39) |
unclassified |
probably benign |
|
|
R3796:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R3797:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R3799:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R4080:Phrf1
|
UTSW |
7 |
140,839,633 (GRCm39) |
unclassified |
probably benign |
|
|
R4081:Phrf1
|
UTSW |
7 |
140,838,970 (GRCm39) |
unclassified |
probably benign |
|
|
R4557:Phrf1
|
UTSW |
7 |
140,838,842 (GRCm39) |
unclassified |
probably benign |
|
|
R5217:Phrf1
|
UTSW |
7 |
140,840,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5218:Phrf1
|
UTSW |
7 |
140,841,214 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5276:Phrf1
|
UTSW |
7 |
140,839,196 (GRCm39) |
unclassified |
probably benign |
|
|
R5442:Phrf1
|
UTSW |
7 |
140,820,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5501:Phrf1
|
UTSW |
7 |
140,839,834 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5695:Phrf1
|
UTSW |
7 |
140,838,378 (GRCm39) |
unclassified |
probably benign |
|
|
R5837:Phrf1
|
UTSW |
7 |
140,839,974 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5907:Phrf1
|
UTSW |
7 |
140,840,453 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5996:Phrf1
|
UTSW |
7 |
140,839,015 (GRCm39) |
unclassified |
probably benign |
|
|
R6024:Phrf1
|
UTSW |
7 |
140,838,898 (GRCm39) |
unclassified |
probably benign |
|
|
R6244:Phrf1
|
UTSW |
7 |
140,817,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6512:Phrf1
|
UTSW |
7 |
140,840,309 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7016:Phrf1
|
UTSW |
7 |
140,817,476 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7311:Phrf1
|
UTSW |
7 |
140,820,846 (GRCm39) |
missense |
unknown |
|
|
R7409:Phrf1
|
UTSW |
7 |
140,839,205 (GRCm39) |
missense |
unknown |
|
|
R7517:Phrf1
|
UTSW |
7 |
140,836,523 (GRCm39) |
missense |
unknown |
|
|
R7560:Phrf1
|
UTSW |
7 |
140,811,138 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7699:Phrf1
|
UTSW |
7 |
140,834,842 (GRCm39) |
missense |
unknown |
|
|
R7700:Phrf1
|
UTSW |
7 |
140,834,842 (GRCm39) |
missense |
unknown |
|
|
R7867:Phrf1
|
UTSW |
7 |
140,836,524 (GRCm39) |
missense |
unknown |
|
|
R7895:Phrf1
|
UTSW |
7 |
140,839,288 (GRCm39) |
missense |
unknown |
|
|
R8179:Phrf1
|
UTSW |
7 |
140,836,493 (GRCm39) |
missense |
unknown |
|
|
R8705:Phrf1
|
UTSW |
7 |
140,838,651 (GRCm39) |
missense |
unknown |
|
|
R8708:Phrf1
|
UTSW |
7 |
140,812,446 (GRCm39) |
missense |
unknown |
|
|
R8748:Phrf1
|
UTSW |
7 |
140,838,148 (GRCm39) |
missense |
unknown |
|
|
R8789:Phrf1
|
UTSW |
7 |
140,836,581 (GRCm39) |
missense |
unknown |
|
|
R8859:Phrf1
|
UTSW |
7 |
140,836,516 (GRCm39) |
missense |
unknown |
|
|
R8991:Phrf1
|
UTSW |
7 |
140,823,671 (GRCm39) |
missense |
unknown |
|
|
R9086:Phrf1
|
UTSW |
7 |
140,839,412 (GRCm39) |
missense |
unknown |
|
|
R9158:Phrf1
|
UTSW |
7 |
140,836,466 (GRCm39) |
missense |
unknown |
|
|
R9287:Phrf1
|
UTSW |
7 |
140,840,055 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9561:Phrf1
|
UTSW |
7 |
140,834,815 (GRCm39) |
missense |
unknown |
|
|
X0027:Phrf1
|
UTSW |
7 |
140,836,481 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Phrf1
|
UTSW |
7 |
140,838,731 (GRCm39) |
missense |
unknown |
|
|
Z1176:Phrf1
|
UTSW |
7 |
140,823,796 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGGATACCAAAGATCCATCGGG -3'
(R):5'- GGTCAAAGGGGTCATAGATTTCG -3'
Sequencing Primer
(F):5'- TAGCACTTGCATCAGCCG -3'
(R):5'- CAAAGGGGTCATAGATTTCGCTTTTG -3'
|
| Posted On |
2021-03-08 |
Incidental Mutation