Mutagenetix > Incidental Mutation

Incidental Mutation 'Z1187:Lrp1b'

665327

Institutional Source

Beutler Lab

Gene Symbol

Lrp1b

Ensembl Gene

ENSMUSG00000049252

Gene Name

low density lipoprotein-related protein 1B

Synonyms

9630004P12Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

Z1187 ()

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

40485258-42543636 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 40640946 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 3499 (N3499K)

Ref Sequence

ENSEMBL: ENSMUSP00000054275 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000052550]

AlphaFold

no structure available at present

Predicted Effect

SMART Domains

Protein: ENSMUSP00000054275
Gene: ENSMUSG00000049252
AA Change: N3499K

Domain	Start	End	E-Value	Type
low complexity region	3	19	N/A	INTRINSIC
low complexity region	35	46	N/A	INTRINSIC
LDLa	62	102	2.97e-12	SMART
LDLa	107	146	1.31e-8	SMART
EGF	150	185	1.95e1	SMART
EGF_CA	186	225	8.37e-8	SMART
LY	256	300	4.06e1	SMART
LY	304	348	1.15e-5	SMART
LY	349	392	1.17e-11	SMART
LY	393	435	1.12e-8	SMART
LY	436	478	2.21e1	SMART
EGF	505	548	2.45e0	SMART
LY	579	621	1.32e-5	SMART
LY	622	665	1.88e-10	SMART
LY	668	717	1.47e-12	SMART
LY	718	760	5.78e-11	SMART
LY	761	802	1.45e0	SMART
EGF_like	828	865	4.55e1	SMART
LDLa	875	914	7.15e-15	SMART
LDLa	916	955	5.26e-13	SMART
LDLa	957	995	6.13e-14	SMART
LDLa	997	1035	6.47e-13	SMART
LDLa	1036	1075	1.76e-14	SMART
LDLa	1083	1121	2.29e-13	SMART
LDLa	1125	1164	3.36e-11	SMART
LDLa	1166	1206	2.57e-7	SMART
EGF	1206	1244	1.58e-3	SMART
EGF	1248	1284	4.56e0	SMART
LY	1311	1353	4.85e-4	SMART
LY	1358	1400	6.49e-14	SMART
LY	1401	1445	8.18e-11	SMART
LY	1446	1490	4.25e-9	SMART
LY	1492	1534	5.4e-2	SMART
EGF	1561	1601	9.41e-2	SMART
LY	1629	1671	3.03e-5	SMART
LY	1672	1716	1.22e-9	SMART
LY	1718	1756	1.02e-2	SMART
LY	1757	1798	8.25e-7	SMART
EGF	1868	1906	4.03e-1	SMART
LY	1933	1975	1.01e-1	SMART
LY	1976	2018	3.03e-14	SMART
LY	2019	2062	2.16e-10	SMART
LY	2063	2105	4.09e-11	SMART
LY	2107	2149	9.96e0	SMART
EGF	2177	2214	2.13e0	SMART
LY	2292	2334	6.96e-5	SMART
LY	2340	2385	1.07e-5	SMART
LY	2386	2428	1.1e-11	SMART
LY	2429	2470	4.78e-3	SMART
EGF	2498	2535	2.03e1	SMART
LDLa	2540	2580	1.1e-6	SMART
LDLa	2582	2619	1.72e-8	SMART
LDLa	2621	2658	2.45e-13	SMART
LDLa	2669	2707	6.53e-9	SMART
LDLa	2712	2749	7.97e-13	SMART
LDLa	2750	2789	1.22e-8	SMART
LDLa	2791	2832	3.07e-14	SMART
LDLa	2835	2873	7.32e-12	SMART
LDLa	2875	2917	1.85e-8	SMART
LDLa	2921	2958	4.76e-11	SMART
EGF_CA	2957	2998	1.79e-7	SMART
EGF_CA	2999	3039	1.85e-9	SMART
LY	3066	3111	2.58e-8	SMART
LY	3112	3152	1.22e-9	SMART
LY	3153	3196	8.84e-7	SMART
LY	3197	3237	3.22e-9	SMART
LY	3238	3279	1.04e-3	SMART
EGF	3307	3345	7.13e-2	SMART
LDLa	3347	3385	9.29e-14	SMART
LDLa	3387	3424	2.25e-12	SMART
LDLa	3426	3464	5.63e-13	SMART
LDLa	3466	3504	1.07e-13	SMART
LDLa	3506	3543	1.35e-15	SMART
EGF_like	3545	3581	2.8e1	SMART
LDLa	3545	3582	1.49e-12	SMART
LDLa	3583	3620	4.21e-12	SMART
LDLa	3624	3661	4.9e-13	SMART
LDLa	3662	3700	9.58e-16	SMART
LDLa	3704	3743	5.38e-10	SMART
LDLa	3745	3784	1.42e-9	SMART
LDLa	3792	3829	3.66e-12	SMART
EGF	3835	3874	3.71e0	SMART
EGF_CA	3875	3912	6.8e-8	SMART
LY	3987	4033	4.24e0	SMART
LY	4050	4093	4.46e-3	SMART
LY	4094	4136	1.73e-9	SMART
EGF	4206	4239	2.45e0	SMART
EGF	4247	4280	2.48e-1	SMART
EGF	4283	4316	1.49e-4	SMART
EGF	4319	4352	1.69e-3	SMART
EGF	4355	4388	1.18e1	SMART
EGF_like	4391	4423	6.67e1	SMART
EGF	4424	4458	1.61e0	SMART
transmembrane domain	4476	4498	N/A	INTRINSIC
low complexity region	4499	4509	N/A	INTRINSIC
low complexity region	4512	4523	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.4%
20x: 98.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016]
PHENOTYPE: Homozygous null mice appear normal, are fertile, have normal brain histology and function, normal plasma cholesterol and fasting triglycerides, and do not develop tumors. [provided by MGI curators]

Allele List at MGI

All alleles(9) : Targeted, knock-out(3) Targeted, other(2) Gene trapped(4)

Other mutations in this stock

Total: 419 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700086D15Rik	A	G	11: 65,044,114 (GRCm39)	W27R	unknown	Het
1700086D15Rik	A	G	11: 65,044,080 (GRCm39)	F38S	unknown	Het
1700086D15Rik	A	C	11: 65,043,809 (GRCm39)	V84G	unknown	Het
1700086D15Rik	T	A	11: 65,043,794 (GRCm39)	Q89L	unknown	Het
1700086D15Rik	A	G	11: 65,044,128 (GRCm39)	L22P	unknown	Het
1810065E05Rik	C	T	11: 58,313,027 (GRCm39)	L27F	probably benign	Het
1810065E05Rik	C	T	11: 58,316,625 (GRCm39)	L202F	probably benign	Het
1810065E05Rik	C	T	11: 58,313,060 (GRCm39)	L38F	possibly damaging	Het
2810021J22Rik	C	T	11: 58,771,361 (GRCm39)	A281V	probably benign	Het
4930438A08Rik	A	G	11: 58,184,844 (GRCm39)	T521A	unknown	Het
4933427D14Rik	G	A	11: 72,067,535 (GRCm39)	T585I	possibly damaging	Het
4933427D14Rik	T	G	11: 72,089,750 (GRCm39)	S45R	probably damaging	Het
4933427D14Rik	C	A	11: 72,089,360 (GRCm39)	A175S	probably benign	Het
4933427D14Rik	G	A	11: 72,089,308 (GRCm39)	P192L	probably benign	Het
4933427D14Rik	T	TCCCCAGC	11: 72,086,590 (GRCm39)		probably null	Het
4933427D14Rik	T	G	11: 72,086,580 (GRCm39)	K277T	probably damaging	Het
4933427D14Rik	A	G	11: 72,086,569 (GRCm39)	C281R	possibly damaging	Het
4933427D14Rik	AAAAGTAA	AAA	11: 72,086,538 (GRCm39)		probably null	Het
4933427D14Rik	GGAAAAG	GG	11: 72,086,536 (GRCm39)		probably null	Het
4933427D14Rik	G	T	11: 72,080,442 (GRCm39)	P408H	probably damaging	Het
Adgra3	G	A	5: 50,136,421 (GRCm39)	A688V	probably damaging	Het
Adh1	T	C	3: 137,992,544 (GRCm39)	I220T	probably damaging	Het
Adh4	T	C	3: 138,125,091 (GRCm39)		probably null	Het
Akap10	T	A	11: 61,806,096 (GRCm39)	S211C	probably benign	Het
Alg10b	C	A	15: 90,112,397 (GRCm39)	L414I	possibly damaging	Het
Alox8	C	T	11: 69,076,873 (GRCm39)	R536Q	probably benign	Het
Alox8	A	G	11: 69,088,322 (GRCm39)	V76A	probably benign	Het
Aloxe3	A	G	11: 69,019,501 (GRCm39)	Q138R	probably benign	Het
Aloxe3	C	T	11: 69,039,429 (GRCm39)	A667V	probably benign	Het
Ank2	A	G	3: 126,749,601 (GRCm39)	F476S	probably damaging	Het
Aplp2	T	A	9: 31,063,637 (GRCm39)	E657V	possibly damaging	Het
Aspa	G	T	11: 73,213,013 (GRCm39)	L110I	probably benign	Het
Atp6v1g3	A	G	1: 138,201,582 (GRCm39)	K27E	possibly damaging	Het
Aurkb	T	C	11: 68,938,696 (GRCm39)	F45S	probably benign	Het
Aurkb	C	T	11: 68,938,692 (GRCm39)	R44W	probably damaging	Het
B9d1	A	T	11: 61,396,029 (GRCm39)		probably benign	Het
BC034090	A	G	1: 155,117,245 (GRCm39)	I291T	probably benign	Het
Borcs6	G	A	11: 68,951,453 (GRCm39)	R277Q	possibly damaging	Het
Btnl10	T	C	11: 58,810,138 (GRCm39)	V93A	probably benign	Het
Btnl10	C	T	11: 58,817,650 (GRCm39)	T250I	unknown	Het
Btnl10	AGAC	AGACGAC	11: 58,814,755 (GRCm39)		probably benign	Het
Btnl10	AAAGA	AAAGAAGA	11: 58,814,753 (GRCm39)		probably benign	Het
Ccdc42	C	T	11: 68,478,017 (GRCm39)		probably benign	Het
Ccdc92b	A	G	11: 74,520,880 (GRCm39)	M61V	possibly damaging	Het
Chd3	C	A	11: 69,239,271 (GRCm39)	E1753D	probably benign	Het
Chd3	A	G	11: 69,252,277 (GRCm39)	W42R	probably benign	Het
Chrna9	T	C	5: 66,134,123 (GRCm39)	F325L	probably benign	Het
Clec3a	G	A	8: 115,144,859 (GRCm39)	V12M	possibly damaging	Het
Cluh	CCCCGAGCC	CCCCGAGCCCGAGCC	11: 74,560,340 (GRCm39)		probably benign	Het
Cluh	TGAGCC	TGAGCCCGAGCC	11: 74,560,355 (GRCm39)		probably benign	Het
Cluh	G	GGGCCTA	11: 74,560,350 (GRCm39)		probably benign	Het
Cluh	CCTGAG	CCTGAGTCTGAG	11: 74,560,347 (GRCm39)		probably benign	Het
Cluh	GCCTGA	GCCTGATCCTGA	11: 74,560,346 (GRCm39)		probably benign	Het
Cluh	CGAGCCTGAGCCTGAGCC	CGAGCCTGAGCCTGAGCCTGAGCC	11: 74,560,343 (GRCm39)		probably benign	Het
Cluh	CCGAGCC	CCGAGCCCGAGCC	11: 74,560,342 (GRCm39)		probably benign	Het
Cnot9	T	A	1: 74,556,285 (GRCm39)	N27K	probably benign	Het
Cntrob	G	A	11: 69,198,882 (GRCm39)	P622L	probably benign	Het
Cntrob	C	T	11: 69,196,404 (GRCm39)	R677H	probably benign	Het
Crybg3	C	T	16: 59,326,608 (GRCm39)	V1041M	probably damaging	Het
Cyb5d1	C	A	11: 69,286,098 (GRCm39)	A8S	probably benign	Het
Cyb5d1	A	G	11: 69,286,028 (GRCm39)	L31P	probably benign	Het
Dnah9	A	C	11: 65,976,000 (GRCm39)	S1350A	probably benign	Het
Dnah9	G	A	11: 66,038,207 (GRCm39)	H110Y	probably benign	Het
Eif2b5	C	T	16: 20,317,671 (GRCm39)	A3V	unknown	Het
Elac2	T	C	11: 64,870,015 (GRCm39)	S27P	probably benign	Het
Epn2	C	A	11: 61,470,460 (GRCm39)		probably benign	Het
Fam114a2	T	C	11: 57,390,623 (GRCm39)	N304D	probably benign	Het
Fam114a2	C	T	11: 57,405,060 (GRCm39)	G14E	probably benign	Het
Fam114a2	A	G	11: 57,374,858 (GRCm39)	S494P	probably benign	Het
Fam114a2	G	A	11: 57,380,940 (GRCm39)	A438V	probably benign	Het
Fam114a2	C	T	11: 57,390,581 (GRCm39)	V318I	probably benign	Het
Fam83g	G	A	11: 61,594,020 (GRCm39)	R518Q	probably benign	Het
Fat2	T	G	11: 55,200,625 (GRCm39)	K816N	probably benign	Het
Fat2	TGTACCTCACCCCAGTACCT	TGTACCT	11: 55,199,796 (GRCm39)		probably null	Het
Fbxw10	G	C	11: 62,738,118 (GRCm39)	R4T	probably benign	Het
Fbxw10	G	A	11: 62,767,671 (GRCm39)	V836I	probably benign	Het
Foxo6	C	T	4: 120,144,332 (GRCm39)	G40R	possibly damaging	Het
Fsd1	C	A	17: 56,300,920 (GRCm39)	P260T	probably benign	Het
Galnt10	G	A	11: 57,656,514 (GRCm39)	V233I	probably benign	Het
Gemin5	T	C	11: 58,016,044 (GRCm39)	S1321G	probably benign	Het
Gemin5	T	C	11: 58,020,897 (GRCm39)	M1097V	probably benign	Het
Gemin5	C	G	11: 58,030,336 (GRCm39)	A830P	probably benign	Het
Gemin5	C	G	11: 58,030,401 (GRCm39)	C808S	probably benign	Het
Gemin5	C	G	11: 58,037,345 (GRCm39)	E623D	probably benign	Het
Gemin5	C	G	11: 58,013,115 (GRCm39)	S1446T	probably benign	Het
Ggnbp2	C	T	11: 84,727,478 (GRCm39)	R481Q	probably benign	Het
Gjc2	T	C	11: 59,067,259 (GRCm39)	S408G	unknown	Het
Gjc2	ACCCTCCCT	ACCCTCCCTCCCT	11: 59,073,561 (GRCm39)		probably benign	Het
Glod4	T	C	11: 76,134,430 (GRCm39)	K14R	probably benign	Het
Glod4	T	C	11: 76,134,431 (GRCm39)	K14E	probably benign	Het
Glod4	C	A	11: 76,133,819 (GRCm39)		probably null	Het
Glod4	A	G	11: 76,133,836 (GRCm39)	V6A	probably benign	Het
Glp2r	C	G	11: 67,600,472 (GRCm39)	G459A	probably benign	Het
Glp2r	C	T	11: 67,630,993 (GRCm39)	V295I	probably benign	Het
Glp2r	A	G	11: 67,631,878 (GRCm39)	V283A	probably benign	Het
Glp2r	T	C	11: 67,631,885 (GRCm39)	I281V	probably benign	Het
Glp2r	T	C	11: 67,633,129 (GRCm39)	T235A	probably benign	Het
Glp2r	A	G	11: 67,635,773 (GRCm39)	V189A	probably benign	Het
Glp2r	C	A	11: 67,661,662 (GRCm39)	A13S	probably benign	Het
Glp2r	C	A	11: 67,600,394 (GRCm39)	R485L	probably damaging	Het
Glp2r	C	A	11: 67,600,470 (GRCm39)	V460F	probably benign	Het
Gm12253	A	C	11: 58,325,686 (GRCm39)	E52D	probably benign	Het
Gm12253	A	G	11: 58,325,658 (GRCm39)	E43G	probably benign	Het
Gm12253	G	C	11: 58,325,367 (GRCm39)	S13T	possibly damaging	Het
Gm12253	G	A	11: 58,331,835 (GRCm39)	A215T	possibly damaging	Het
Gm12253	G	A	11: 58,326,309 (GRCm39)	S108N	probably benign	Het
Gm12253	A	C	11: 58,326,237 (GRCm39)	E84A	probably benign	Het
Gm12258	T	G	11: 58,749,126 (GRCm39)	S100R		Het
Gm12258	C	T	11: 58,749,262 (GRCm39)	R146W		Het
Gm12258	G	C	11: 58,750,690 (GRCm39)	G622R	unknown	Het
Gm12258	T	A	11: 58,750,014 (GRCm39)		probably benign	Het
Gm12258	A	G	11: 58,750,013 (GRCm39)		probably benign	Het
Gm12258	A	T	11: 58,749,833 (GRCm39)	E336V	unknown	Het
Gm12258	G	A	11: 58,749,776 (GRCm39)	G317E	unknown	Het
Gm12258	G	A	11: 58,749,764 (GRCm39)	R313H	unknown	Het
Golga5	A	G	12: 102,440,853 (GRCm39)	E196G	probably benign	Het
Gps2	C	T	11: 69,807,130 (GRCm39)	A60V	probably benign	Het
Gucy2e	C	G	11: 69,127,429 (GRCm39)	G15R	unknown	Het
Gucy2e	C	A	11: 69,114,431 (GRCm39)	A1033S	probably benign	Het
Guk1	G	A	11: 59,082,747 (GRCm39)		probably benign	Het
Haspin	T	C	11: 73,028,174 (GRCm39)	Q305R	probably benign	Het
Haspin	A	G	11: 73,028,777 (GRCm39)	L104P	probably benign	Het
Hes7	T	C	11: 69,013,782 (GRCm39)	S214P	probably benign	Het
Hic1	G	A	11: 75,058,352 (GRCm39)	T179M	probably damaging	Het
Iba57	AG	AGCG	11: 59,052,330 (GRCm39)		probably null	Het
Iba57	CAGA	CAGAGA	11: 59,052,329 (GRCm39)		probably null	Het
Iba57	C	G	11: 59,053,865 (GRCm39)	G36R	unknown	Het
Iba57	T	C	11: 59,052,384 (GRCm39)	T86A	unknown	Het
Iba57	T	C	11: 59,052,381 (GRCm39)	T87A	unknown	Het
Ifi207	G	A	1: 173,558,093 (GRCm39)	T215I	unknown	Het
Iftap	T	C	2: 101,440,950 (GRCm39)	K18E	probably benign	Het
Igtp	C	G	11: 58,097,791 (GRCm39)	L321V	possibly damaging	Het
Igtp	T	G	11: 58,097,169 (GRCm39)	D113E	probably damaging	Het
Igtp	C	G	11: 58,097,944 (GRCm39)	L372V	probably benign	Het
Irgm2	A	C	11: 58,110,951 (GRCm39)	H214P	probably benign	Het
Irgm2	G	A	11: 58,110,924 (GRCm39)	S205N	probably benign	Het
Irgm2	G	A	11: 58,110,833 (GRCm39)	V175I	probably benign	Het
Irgm2	A	G	11: 58,110,389 (GRCm39)	N27D	probably benign	Het
Irgm2	G	T	11: 58,111,238 (GRCm39)	A310S	possibly damaging	Het
Irgm2	C	G	11: 58,111,389 (GRCm39)	T360S	probably benign	Het
Irgm2	T	A	11: 58,110,339 (GRCm39)	V10D	probably benign	Het
Irgm2	T	C	11: 58,110,780 (GRCm39)	L157S	probably benign	Het
Irgm2	T	C	11: 58,110,738 (GRCm39)	I143T	probably benign	Het
Itgae	T	A	11: 72,994,713 (GRCm39)	L22M	possibly damaging	Het
Itgae	A	T	11: 72,994,786 (GRCm39)	Q46L	probably damaging	Het
Itgae	A	G	11: 73,006,466 (GRCm39)	H378R	probably benign	Het
Itgae	G	A	11: 73,008,913 (GRCm39)	V465I	probably benign	Het
Itgae	A	T	11: 73,012,757 (GRCm39)	K696N	probably benign	Het
Itgae	G	T	11: 73,012,783 (GRCm39)	G705V	probably benign	Het
Itgae	C	G	11: 73,024,953 (GRCm39)	S1028W	probably benign	Het
Kif1c	C	T	11: 70,614,940 (GRCm39)	P578L	probably benign	Het
Klhdc7a	A	G	4: 139,693,852 (GRCm39)	I365T	probably damaging	Het
Kmt2d	T	C	15: 98,749,625 (GRCm39)	N2656D	unknown	Het
Larp1	G	A	11: 57,933,166 (GRCm39)	V257I	probably benign	Het
Llgl1	ACCCCAGCCCTTCTGATTACTGCCCTCCCCAGC	ACCCCAGC	11: 60,603,923 (GRCm39)		probably null	Het
Lypd8	C	A	11: 58,275,475 (GRCm39)	A70E	possibly damaging	Het
Lypd8	G	A	11: 58,275,489 (GRCm39)	E75K	probably benign	Het
Lypd8	CAATCACCAACA	CAATCACCAACAGTTCCCTCGCCTCTGTTACCCCACAAATCACCAACA	11: 58,281,059 (GRCm39)		probably benign	Het
Lypd8	T	C	11: 58,273,601 (GRCm39)	Y27H	probably benign	Het
Lypd8l	A	G	11: 58,503,387 (GRCm39)	L47P	probably benign	Het
Lypd8l	G	A	11: 58,499,335 (GRCm39)	P161L	probably benign	Het
Lypd8l	T	G	11: 58,503,397 (GRCm39)	S44R	probably benign	Het
Mapk7	CGCTGGTGCTGG	CGCTGGTGCTGGTGCTGG	11: 61,381,038 (GRCm39)		probably benign	Het
Mapk7	TGGGGCAGGGGCAGGGGCAGG	TGGCGCTGGGGCAGGGGCAGGGGCAGGGGCAGG	11: 61,381,053 (GRCm39)		probably benign	Het
Mfap3	A	T	11: 57,418,866 (GRCm39)	I9F	possibly damaging	Het
Mfap3	G	A	11: 57,418,902 (GRCm39)	G21S	probably benign	Het
Mrm3	G	A	11: 76,134,903 (GRCm39)	R102K	probably benign	Het
Mrm3	C	T	11: 76,138,221 (GRCm39)	P203L	probably benign	Het
Mrpl22	G	A	11: 58,062,521 (GRCm39)	A4T	unknown	Het
Mrpl55	A	G	11: 59,094,999 (GRCm39)		probably null	Het
Mrpl55	A	T	11: 59,095,415 (GRCm39)	L26F	probably benign	Het
Myh1	A	C	11: 67,095,272 (GRCm39)	T211P	probably benign	Het
Myh8	A	C	11: 67,188,312 (GRCm39)	N991T	probably benign	Het
Myo18a	C	A	11: 77,744,643 (GRCm39)	F1970L	possibly damaging	Het
Myocd	A	G	11: 65,075,418 (GRCm39)	S697P	probably benign	Het
Nlgn2	A	G	11: 69,719,220 (GRCm39)	V210A	possibly damaging	Het
Nlrp1a	T	C	11: 71,014,914 (GRCm39)	E112G	probably benign	Het
Nlrp1a	T	C	11: 70,990,442 (GRCm39)	I1038V	probably benign	Het
Nlrp1a	C	T	11: 70,988,077 (GRCm39)	R1131Q	probably damaging	Het
Nlrp1a	T	C	11: 70,983,069 (GRCm39)	K1299R	probably benign	Het
Nlrp1a	C	G	11: 71,033,355 (GRCm39)		probably null	Het
Nlrp1b	A	C	11: 71,072,539 (GRCm39)	S435A	probably benign	Het
Nlrp1b	C	A	11: 71,072,534 (GRCm39)	M436I	probably benign	Het
Nlrp1b	T	C	11: 71,073,503 (GRCm39)	I113M	probably benign	Het
Nlrp1b	T	A	11: 71,073,396 (GRCm39)	Q149L	probably benign	Het
Nlrp1b	A	T	11: 71,073,378 (GRCm39)	M155K	probably benign	Het
Nlrp1b	C	G	11: 71,073,370 (GRCm39)	E158Q	probably benign	Het
Nlrp1b	T	C	11: 71,073,280 (GRCm39)	T188A	probably benign	Het
Nlrp1b	A	T	11: 71,073,266 (GRCm39)	D192E	probably benign	Het
Nlrp1b	A	G	11: 71,073,148 (GRCm39)	Y232H	probably benign	Het
Nlrp1b	A	G	11: 71,072,625 (GRCm39)	I406T	probably benign	Het
Nmur2	T	C	11: 55,931,104 (GRCm39)	I202M	probably benign	Het
Obscn	G	T	11: 58,984,334 (GRCm39)	A1707D	possibly damaging	Het
Obscn	C	T	11: 58,984,335 (GRCm39)	A1707T	probably benign	Het
Obscn	G	A	11: 58,984,385 (GRCm39)	A1690V	probably benign	Het
Obscn	C	T	11: 58,990,735 (GRCm39)	A1613T	possibly damaging	Het
Obscn	T	C	11: 58,990,755 (GRCm39)	H1606R	probably benign	Het
Obscn	C	G	11: 58,994,167 (GRCm39)	A1572P	probably damaging	Het
Obscn	T	C	11: 58,994,340 (GRCm39)	H1514R	probably benign	Het
Obscn	G	A	11: 58,994,364 (GRCm39)	A1506V	probably benign	Het
Obscn	T	C	11: 59,003,380 (GRCm39)	E1306G	probably benign	Het
Obscn	T	C	11: 59,013,563 (GRCm39)	M1095V	probably benign	Het
Obscn	C	T	11: 59,018,892 (GRCm39)	A949T	probably benign	Het
Obscn	C	T	11: 59,018,895 (GRCm39)	V973M	probably damaging	Het
Obscn	G	T	11: 59,020,663 (GRCm39)	L794M	probably benign	Het
Obscn	C	T	11: 59,021,449 (GRCm39)	R797H	probably damaging	Het
Obscn	C	T	11: 59,023,937 (GRCm39)	A578T	possibly damaging	Het
Obscn	G	A	11: 59,024,066 (GRCm39)	P535S	probably damaging	Het
Obscn	C	G	11: 59,024,072 (GRCm39)	A533P	probably benign	Het
Obscn	T	C	11: 59,026,505 (GRCm39)	I233V	probably benign	Het
Obscn	C	T	11: 58,940,306 (GRCm39)	D5354N		Het
Obscn	C	A	11: 58,940,614 (GRCm39)	R4593S	possibly damaging	Het
Obscn	T	C	11: 58,940,623 (GRCm39)	T5307A		Het
Obscn	G	A	11: 58,942,383 (GRCm39)	T4372M	probably benign	Het
Obscn	T	C	11: 58,943,439 (GRCm39)	M4237V	probably benign	Het
Obscn	C	T	11: 58,944,594 (GRCm39)	R4700Q	probably benign	Het
Obscn	T	C	11: 58,944,651 (GRCm39)	K4681R	probably benign	Het
Obscn	T	C	11: 58,945,044 (GRCm39)	E4658G	probably benign	Het
Obscn	C	T	11: 58,945,176 (GRCm39)	R4614Q	probably benign	Het
Obscn	T	C	11: 58,946,331 (GRCm39)	D4458G	probably damaging	Het
Obscn	C	T	11: 58,946,340 (GRCm39)	R4455K	probably benign	Het
Obscn	G	T	11: 58,946,936 (GRCm39)	A4066E	possibly damaging	Het
Obscn	A	G	11: 58,947,595 (GRCm39)	M4478T		Het
Obscn	C	A	11: 58,951,823 (GRCm39)	G3977W	probably damaging	Het
Obscn	C	T	11: 58,952,388 (GRCm39)	G3894R	probably benign	Het
Obscn	CCACACACACACAC	CCACACACACAC	11: 58,954,279 (GRCm39)		probably null	Het
Obscn	T	C	11: 58,954,300 (GRCm39)	T4037A		Het
Obscn	T	C	11: 58,954,402 (GRCm39)	K3727E	probably damaging	Het
Obscn	G	A	11: 58,957,973 (GRCm39)	R3576C	probably benign	Het
Obscn	C	T	11: 58,958,655 (GRCm39)	V3433I	probably benign	Het
Obscn	G	A,C	11: 58,960,659 (GRCm39)		silent	Het
Obscn	C	A	11: 58,960,757 (GRCm39)	A3185S	probably benign	Het
Obscn	C	T	11: 58,967,334 (GRCm39)	V2792I	possibly damaging	Het
Obscn	G	A	11: 58,891,715 (GRCm39)	A6939V	probably benign	Het
Obscn	C	G	11: 58,900,019 (GRCm39)	G938A	probably benign	Het
Obscn	G	C	11: 58,904,014 (GRCm39)	T7320S	probably benign	Het
Obscn	C	T	11: 58,921,934 (GRCm39)	R5954Q	probably damaging	Het
Obscn	G	C	11: 58,929,976 (GRCm39)	P5080A	probably benign	Het
Obscn	T	A	11: 58,929,990 (GRCm39)	Q5075L	probably damaging	Het
Obscn	T	C	11: 58,932,601 (GRCm39)	I4869V	probably benign	Het
Obscn	T	C	11: 58,933,776 (GRCm39)	T5363A	probably benign	Het
Obscn	G	A	11: 58,933,853 (GRCm39)	A5337V	probably benign	Het
Obscn	G	A	11: 58,933,878 (GRCm39)	R5329C	probably benign	Het
Obscn	G	A	11: 58,969,984 (GRCm39)	R53C	probably damaging	Het
Obscn	C	T	11: 58,984,239 (GRCm39)	V1739M	possibly damaging	Het
Obscn	A	G	11: 58,984,142 (GRCm39)	F1771S	probably benign	Het
Obscn	A	G	11: 58,977,565 (GRCm39)	V1845A	probably benign	Het
Obscn	T	C	11: 58,977,527 (GRCm39)	R1858G	probably benign	Het
Obscn	C	T	11: 58,977,505 (GRCm39)	R1865H	probably benign	Het
Obscn	C	A	11: 58,972,698 (GRCm39)	G2116V	possibly damaging	Het
Obscn	C	G	11: 58,970,722 (GRCm39)	V2328L	probably benign	Het
Or11l3	A	C	11: 58,516,732 (GRCm39)	C46G	possibly damaging	Het
Or11l3	T	G	11: 58,516,619 (GRCm39)	K84N	probably benign	Het
Or11l3	G	A	11: 58,516,588 (GRCm39)	P95S	probably benign	Het
Or11l3	C	G	11: 58,516,130 (GRCm39)	G61R	probably benign	Het
Or11l3	G	A	11: 58,516,075 (GRCm39)	S79F	probably benign	Het
Or14j10	A	G	17: 37,934,735 (GRCm39)	S264P	probably damaging	Het
Or2ab1	A	C	11: 58,488,344 (GRCm39)	I35L	probably benign	Het
Or2ab1	A	G	11: 58,488,776 (GRCm39)	S179G	probably benign	Het
Or2ab1	A	G	11: 58,488,491 (GRCm39)	S84G	possibly damaging	Het
Or2ab1	A	G	11: 58,488,356 (GRCm39)	I39V	probably benign	Het
Or2ak4	G	A	11: 58,648,793 (GRCm39)	A101T	probably benign	Het
Or2ak4	A	C	11: 58,649,186 (GRCm39)	K232Q	probably benign	Het
Or2ak4	A	C	11: 58,649,168 (GRCm39)	I226L	probably benign	Het
Or2ak4	G	A	11: 58,649,153 (GRCm39)	V221M	probably damaging	Het
Or2ak4	A	G	11: 58,648,931 (GRCm39)	S147G	probably benign	Het
Or2ak4	C	T	11: 58,648,895 (GRCm39)	L135F	probably benign	Het
Or2ak5	G	A	11: 58,611,922 (GRCm39)		probably benign	Het
Or2ak6	C	A	11: 58,593,222 (GRCm39)	Q232K	probably benign	Het
Or2ak6	C	T	11: 58,593,153 (GRCm39)	L209F	possibly damaging	Het
Or2ak6	A	C	11: 58,592,784 (GRCm39)	I86L	probably benign	Het
Or2ak7	T	C	11: 58,574,815 (GRCm39)	F39L	probably benign	Het
Or2ak7	G	T	11: 58,574,758 (GRCm39)	D20Y	probably benign	Het
Or2ak7	T	C	11: 58,575,548 (GRCm39)	L283P	probably benign	Het
Or2ak7	C	T	11: 58,575,289 (GRCm39)	H197Y	probably benign	Het
Or2ak7	G	A	11: 58,575,083 (GRCm39)	R128Q	probably benign	Het
Or2ak7	G	A	11: 58,574,941 (GRCm39)	V81M	probably benign	Het
Or2av9	C	T	11: 58,381,123 (GRCm39)	A153T	probably benign	Het
Or2av9	C	A	11: 58,380,574 (GRCm39)	E336*	probably null	Het
Or2av9	T	C	11: 58,381,314 (GRCm39)	Q89R	probably benign	Het
Or2t29	G	T	11: 58,434,272 (GRCm39)	S23Y	probably benign	Het
Or2t43	G	A	11: 58,457,388 (GRCm39)	A261V	probably benign	Het
Or2t43	C	T	11: 58,457,920 (GRCm39)	V84I	probably benign	Het
Or2t43	A	T	11: 58,457,521 (GRCm39)	S217T	probably benign	Het
Or2t44	A	G	11: 58,677,773 (GRCm39)	T238A	probably damaging	Het
Or2t46	G	A	11: 58,471,828 (GRCm39)	V53I	probably benign	Het
Or2t46	T	G	11: 58,472,122 (GRCm39)	L151V	probably benign	Het
Or2t46	G	C	11: 58,472,483 (GRCm39)	S271T	probably benign	Het
Or2t46	C	T	11: 58,471,750 (GRCm39)	H27Y	probably benign	Het
Or2t46	T	C	11: 58,471,757 (GRCm39)	V29A	probably benign	Het
Or2t47	C	T	11: 58,442,801 (GRCm39)	S88N	probably benign	Het
Or2t47	C	T	11: 58,442,940 (GRCm39)	A42T	probably benign	Het
Or2t47	T	C	11: 58,442,387 (GRCm39)	K226R	probably benign	Het
Or2t49	C	A	11: 58,392,936 (GRCm39)	V155F	probably benign	Het
Or2t49	GGTGGATTGGTATGTGGAT	GGTGGAT	11: 58,393,212 (GRCm39)		probably benign	Het
Or2t49	C	G	11: 58,393,287 (GRCm39)	V38L	probably benign	Het
Or2t49	C	T	11: 58,393,396 (GRCm39)	M1I	probably null	Het
Or2t49	T	C	11: 58,392,474 (GRCm39)	M309V	probably benign	Het
Or2t49	T	C	11: 58,392,927 (GRCm39)	I158V	probably benign	Het
Or2w3	T	G	11: 58,557,342 (GRCm39)	I319R	probably benign	Het
Or2w3b	C	A	11: 58,624,048 (GRCm39)		probably benign	Het
Or2w3b	T	G	11: 58,623,200 (GRCm39)	N264H	probably benign	Het
Or2w3b	T	C	11: 58,623,475 (GRCm39)	H172R	probably benign	Het
Or2w3b	G	A	11: 58,623,295 (GRCm39)	A232V	probably benign	Het
Or5af2	T	C	11: 58,708,122 (GRCm39)	V96A	probably benign	Het
Or5af2	A	G	11: 58,707,887 (GRCm39)	I18V	probably benign	Het
Or5af2	C	G	11: 58,708,644 (GRCm39)	P270R	probably benign	Het
Or5af2	T	C	11: 58,708,508 (GRCm39)	C225R	probably benign	Het
Or5af2	C	G	11: 58,708,243 (GRCm39)	H136Q	probably benign	Het
Or5af2	A	C	11: 58,708,220 (GRCm39)	I129L	probably benign	Het
Or6k2	C	A	1: 173,986,907 (GRCm39)	C189*	probably null	Het
Or9e1	G	T	11: 58,731,945 (GRCm39)	A2S	probably benign	Het
Or9e1	G	C	11: 58,731,907 (GRCm39)		probably benign	Het
Or9e1	A	G	11: 58,732,615 (GRCm39)	H225R	probably benign	Het
Or9e1	G	A	11: 58,732,569 (GRCm39)	A210T	probably benign	Het
Or9e1	C	T	11: 58,732,032 (GRCm39)	L31F	probably benign	Het
Or9e1	T	C	11: 58,732,084 (GRCm39)	I48T	probably benign	Het
Otx1	C	A	11: 21,947,037 (GRCm39)	A91S	probably damaging	Het
Ovca2	T	C	11: 75,069,528 (GRCm39)	T32A	probably benign	Het
Pfkfb1	T	G	X: 149,391,627 (GRCm39)	V25G	probably damaging	Het
Pimreg	G	A	11: 71,935,979 (GRCm39)	R154H	probably damaging	Het
Pimreg	TCACA	TCA	11: 71,935,801 (GRCm39)		probably benign	Het
Pitpnm3	C	T	11: 72,010,969 (GRCm39)	R21Q	probably benign	Het
Pitpnm3	T	C	11: 71,954,955 (GRCm39)	K520E	probably benign	Het
Ppp1r12b	C	G	1: 134,883,262 (GRCm39)	V87L	probably benign	Het
Pramel13	A	G	4: 144,122,517 (GRCm39)	L9P	probably damaging	Het
Prpsap2	A	C	11: 61,647,078 (GRCm39)	V21G	possibly damaging	Het
Rabep1	C	CT	11: 70,830,910 (GRCm39)		probably null	Het
Rai1	A	G	11: 60,078,389 (GRCm39)	N818D	probably benign	Het
Rap1gap2	C	T	11: 74,487,721 (GRCm39)	E52K	probably benign	Het
Rc3h2	T	C	2: 37,289,612 (GRCm39)	H400R	possibly damaging	Het
Rnf112	A	G	11: 61,341,775 (GRCm39)	L343P	unknown	Het
Rnf167	C	CACAGGGA	11: 70,541,646 (GRCm39)		probably null	Het
Rtn4rl1	C	T	11: 75,156,863 (GRCm39)	P432S	probably benign	Het
Shisa6	CGCCGC	CGCCGCAGCCGC	11: 66,416,533 (GRCm39)		probably benign	Het
Shisa6	CGCCGC	CGCCGCGGCCGC	11: 66,416,524 (GRCm39)		probably benign	Het
Slc2a4	GCC	G	11: 69,834,819 (GRCm39)		probably null	Het
Slc2a4	GGCCG	GG	11: 69,834,818 (GRCm39)		probably benign	Het
Slc6a4	A	G	11: 76,903,858 (GRCm39)	K152R	probably benign	Het
Slc6a4	G	A	11: 76,901,382 (GRCm39)	G39E	probably benign	Het
Smcr8	T	C	11: 60,669,932 (GRCm39)	V360A	probably benign	Het
Smcr8	A	G	11: 60,668,806 (GRCm39)		probably benign	Het
Smcr8	C	A	11: 60,670,699 (GRCm39)	R616S	probably benign	Het
Smg6	G	T	11: 75,047,092 (GRCm39)	A1262S	probably benign	Het
Spata31h1	CGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGTATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGG	CGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGCATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGGATGTATGCAGGAGAATCTGCACACTGAGGACTTGGCCCTGGG	10: 82,124,390 (GRCm39)		probably benign	Het
Spns3	T	C	11: 72,440,863 (GRCm39)	I58V	probably benign	Het
Spns3	T	C	11: 72,440,986 (GRCm39)	S17G	probably benign	Het
Spns3	G	A	11: 72,440,917 (GRCm39)	P40S	probably benign	Het
Srebf1	C	T	11: 60,097,061 (GRCm39)	V256M	probably benign	Het
Tekt1	T	C	11: 72,250,597 (GRCm39)	Q33R	probably benign	Het
Timm22	T	G	11: 76,297,943 (GRCm39)	V18G	probably benign	Het
Tmem102	C	G	11: 69,695,902 (GRCm39)	G53A	possibly damaging	Het
Tmem102	G	C	11: 69,695,927 (GRCm39)	R45G	probably benign	Het
Tmem11	A	G	11: 60,766,658 (GRCm39)		probably benign	Het
Tom1l2	C	T	11: 60,132,682 (GRCm39)	A414T	probably benign	Het
Tomm20l	ACAAGATTC	AC	12: 71,168,758 (GRCm39)		probably null	Het
Top3a	C	T	11: 60,641,410 (GRCm39)	G425S	probably benign	Het
Trim16	T	C	11: 62,731,572 (GRCm39)	V481A	probably benign	Het
Trim16	G	A	11: 62,727,643 (GRCm39)	E322K	probably benign	Het
Trim16	A	AAGC	11: 62,711,521 (GRCm39)		probably benign	Het
Trim16	GA	GAACA	11: 62,711,520 (GRCm39)		probably benign	Het
Trim16	TGAAGA	TGAAGAAGA	11: 62,711,516 (GRCm39)		probably benign	Het
Trim16	G	C	11: 62,711,502 (GRCm39)	V58L	probably benign	Het
Trim16	C	T	11: 62,711,428 (GRCm39)	A33V	probably benign	Het
Trim16	C	A	11: 62,731,675 (GRCm39)	D515E	probably benign	Het
Trim17	G	A	11: 58,856,331 (GRCm39)	M129I	probably benign	Het
Trim17	A	G	11: 58,861,272 (GRCm39)	N259S	probably benign	Het
Trim23	G	A	13: 104,315,395 (GRCm39)	A3T	probably benign	Het
Trim58	C	A	11: 58,531,684 (GRCm39)	L131M	possibly damaging	Het
Trim58	A	G	11: 58,542,486 (GRCm39)	N482S	probably benign	Het
Trmt1l	A	G	1: 151,333,331 (GRCm39)	N642S	possibly damaging	Het
Trpv1	C	G	11: 73,131,427 (GRCm39)	P322A	possibly damaging	Het
Trpv1	C	A	11: 73,145,117 (GRCm39)	D734E	probably benign	Het
Trpv3	A	G	11: 73,174,502 (GRCm39)	T290A	probably benign	Het
Trpv3	G	A	11: 73,169,803 (GRCm39)	A125T	probably benign	Het
Trpv3	C	T	11: 73,160,513 (GRCm39)	A9V	probably benign	Het
Tvp23b	A	C	11: 62,772,769 (GRCm39)	N7H	possibly damaging	Het
Usp43	AGGGC	AGGGCAGGGGATGAACCTCGGGC	11: 67,746,545 (GRCm39)		probably benign	Het
Usp43	C	T	11: 67,747,332 (GRCm39)	G792S	probably benign	Het
Vamp2	C	T	11: 68,979,411 (GRCm39)		probably benign	Het
Vamp2	G	A	11: 68,980,889 (GRCm39)	G124R	possibly damaging	Het
Vmn2r15	G	T	5: 109,434,529 (GRCm39)	P725H	probably damaging	Het
Vmn2r18	T	C	5: 151,508,497 (GRCm39)	D209G	probably benign	Het
Wdr4	C	T	17: 31,731,177 (GRCm39)	G61E	probably damaging	Het
Xaf1	G	C	11: 72,199,856 (GRCm39)	V198L	unknown	Het
Xaf1	GGCT	GGCTGGCCAGCT	11: 72,199,846 (GRCm39)		probably null	Het
Xaf1	T	G	11: 72,199,792 (GRCm39)	C176W	unknown	Het
Xaf1	A	G	11: 72,199,476 (GRCm39)	E71G	probably benign	Het
Xaf1	C	A	11: 72,197,434 (GRCm39)	L137I	probably benign	Het
Xaf1	G	C	11: 72,197,429 (GRCm39)	C135S	probably damaging	Het
Xaf1	G	A	11: 72,197,426 (GRCm39)	R134H	probably benign	Het
Xaf1	T	C	11: 72,199,881 (GRCm39)	L206S	unknown	Het
Zfhx4	C	G	3: 5,308,067 (GRCm39)	S431C	probably damaging	Het
Zfp286	G	A	11: 62,675,782 (GRCm39)	T60M	probably damaging	Het
Zfp286	A	G	11: 62,678,795 (GRCm39)	V44A	probably benign	Het
Zfp287	G	A	11: 62,613,757 (GRCm39)	R225*	probably null	Het
Zfp287	C	T	11: 62,604,633 (GRCm39)	R758H	probably benign	Het
Zfp287	C	G	11: 62,606,175 (GRCm39)	C244S	probably benign	Het
Zfp39	T	C	11: 58,781,274 (GRCm39)	D496G	possibly damaging	Het
Zfp39	G	C	11: 58,781,273 (GRCm39)	D496E	probably benign	Het
Zfp39	G	C	11: 58,781,130 (GRCm39)	T544R	possibly damaging	Het
Zfp39	A	C	11: 58,780,873 (GRCm39)	Y630D	probably benign	Het
Zfp39	G	C	11: 58,780,871 (GRCm39)	Y630*	probably null	Het
Zfp39	T	G	11: 58,791,409 (GRCm39)	S93R	probably benign	Het
Zfp39	G	T	11: 58,791,407 (GRCm39)	S93R	probably benign	Het
Zfp39	T	C	11: 58,782,142 (GRCm39)	K207E	probably benign	Het
Zfp39	A	G	11: 58,782,123 (GRCm39)	I213T	probably benign	Het
Zfp39	T	A	11: 58,781,967 (GRCm39)	H265L	probably damaging	Het
Zfp39	T	C	11: 58,781,526 (GRCm39)	N412S	possibly damaging	Het
Zfp39	G	T	11: 58,781,597 (GRCm39)	N388K	probably benign	Het
Zfp39	A	G	11: 58,781,605 (GRCm39)	S386P	probably benign	Het
Zfp39	A	C	11: 58,781,702 (GRCm39)	H353Q	probably damaging	Het
Zfp39	A	C	11: 58,781,712 (GRCm39)	V350G	probably benign	Het
Zfp39	A	G	11: 58,781,724 (GRCm39)	V346A	probably benign	Het
Zfp39	T	A	11: 58,781,751 (GRCm39)	K337M	probably benign	Het
Zfp672	G	T	11: 58,220,452 (GRCm39)	T49K	unknown	Het
Zfp692	G	T	11: 58,199,859 (GRCm39)	E149D	probably benign	Het
Zfp692	G	A	11: 58,200,844 (GRCm39)	V242I	probably benign	Het
Zzef1	G	A	11: 72,780,008 (GRCm39)	R1927H	probably benign	Het

Other mutations in Lrp1b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00484:Lrp1b	APN	2	41,000,873 (GRCm39)	missense	probably damaging	1.00
IGL00543:Lrp1b	APN	2	41,358,960 (GRCm39)	missense	possibly damaging	0.69
IGL00578:Lrp1b	APN	2	40,569,185 (GRCm39)	missense	unknown
IGL01020:Lrp1b	APN	2	40,888,259 (GRCm39)	missense	probably damaging	1.00
IGL01092:Lrp1b	APN	2	40,640,959 (GRCm39)	missense	probably damaging	0.97
IGL01155:Lrp1b	APN	2	41,660,947 (GRCm39)	missense	probably benign	0.17
IGL01361:Lrp1b	APN	2	41,000,763 (GRCm39)	splice site	probably benign
IGL01377:Lrp1b	APN	2	40,491,550 (GRCm39)	missense	probably damaging	1.00
IGL01459:Lrp1b	APN	2	40,750,726 (GRCm39)	missense	probably damaging	0.97
IGL01473:Lrp1b	APN	2	40,501,498 (GRCm39)	missense	probably damaging	0.97
IGL01528:Lrp1b	APN	2	40,809,194 (GRCm39)	missense	probably damaging	0.99
IGL01536:Lrp1b	APN	2	41,000,895 (GRCm39)	missense	probably benign	0.01
IGL01564:Lrp1b	APN	2	40,567,498 (GRCm39)	splice site	probably benign
IGL01747:Lrp1b	APN	2	40,750,697 (GRCm39)	missense	probably damaging	1.00
IGL01764:Lrp1b	APN	2	40,587,454 (GRCm39)	missense	unknown
IGL01783:Lrp1b	APN	2	41,202,584 (GRCm39)	missense	probably damaging	1.00
IGL01802:Lrp1b	APN	2	41,401,494 (GRCm39)	missense	probably benign	0.07
IGL01826:Lrp1b	APN	2	41,339,246 (GRCm39)	missense	probably damaging	1.00
IGL01884:Lrp1b	APN	2	41,174,225 (GRCm39)	nonsense	probably null
IGL01908:Lrp1b	APN	2	40,592,816 (GRCm39)	missense	probably benign
IGL01935:Lrp1b	APN	2	41,158,367 (GRCm39)	missense	probably damaging	1.00
IGL01959:Lrp1b	APN	2	41,202,539 (GRCm39)	missense	probably damaging	0.99
IGL02010:Lrp1b	APN	2	41,358,954 (GRCm39)	missense	probably damaging	1.00
IGL02022:Lrp1b	APN	2	41,172,172 (GRCm39)	missense	probably damaging	1.00
IGL02028:Lrp1b	APN	2	41,401,464 (GRCm39)	missense	probably damaging	1.00
IGL02034:Lrp1b	APN	2	41,158,382 (GRCm39)	nonsense	probably null
IGL02043:Lrp1b	APN	2	40,587,537 (GRCm39)	missense	probably null	0.44
IGL02066:Lrp1b	APN	2	41,001,091 (GRCm39)	nonsense	probably null
IGL02085:Lrp1b	APN	2	40,779,321 (GRCm39)	missense	probably benign
IGL02137:Lrp1b	APN	2	40,620,700 (GRCm39)	splice site	probably benign
IGL02218:Lrp1b	APN	2	41,185,684 (GRCm39)	missense	probably benign	0.11
IGL02409:Lrp1b	APN	2	41,335,208 (GRCm39)	missense	possibly damaging	0.93
IGL02513:Lrp1b	APN	2	41,000,765 (GRCm39)	critical splice donor site	probably null
IGL02543:Lrp1b	APN	2	40,760,413 (GRCm39)	missense	possibly damaging	0.89
IGL02701:Lrp1b	APN	2	41,136,029 (GRCm39)	missense	possibly damaging	0.50
IGL02728:Lrp1b	APN	2	40,691,410 (GRCm39)	missense	probably benign	0.03
IGL02739:Lrp1b	APN	2	41,388,227 (GRCm39)	missense	probably damaging	1.00
IGL02748:Lrp1b	APN	2	40,592,761 (GRCm39)	missense	probably damaging	0.99
IGL02754:Lrp1b	APN	2	40,592,806 (GRCm39)	missense	probably benign	0.02
IGL02797:Lrp1b	APN	2	41,561,069 (GRCm39)	missense
IGL02813:Lrp1b	APN	2	40,569,229 (GRCm39)	critical splice acceptor site	probably null
IGL02831:Lrp1b	APN	2	41,083,603 (GRCm39)	missense	probably damaging	1.00
IGL02869:Lrp1b	APN	2	40,591,842 (GRCm39)	missense	unknown
IGL02946:Lrp1b	APN	2	41,202,571 (GRCm39)	missense	probably damaging	1.00
IGL02952:Lrp1b	APN	2	41,396,715 (GRCm39)	missense	probably benign	0.33
IGL02958:Lrp1b	APN	2	41,192,928 (GRCm39)	missense	probably damaging	1.00
IGL02977:Lrp1b	APN	2	40,620,747 (GRCm39)	missense	probably damaging	1.00
IGL03001:Lrp1b	APN	2	40,817,901 (GRCm39)	missense	probably damaging	1.00
IGL03010:Lrp1b	APN	2	42,213,618 (GRCm39)	missense	possibly damaging	0.94
IGL03060:Lrp1b	APN	2	40,527,765 (GRCm39)	missense	probably benign	0.04
IGL03129:Lrp1b	APN	2	41,202,478 (GRCm39)	splice site	probably benign
IGL03166:Lrp1b	APN	2	41,001,050 (GRCm39)	missense	probably damaging	1.00
IGL03170:Lrp1b	APN	2	40,587,456 (GRCm39)	missense	unknown
IGL03195:Lrp1b	APN	2	41,361,134 (GRCm39)	missense	possibly damaging	0.95
IGL03224:Lrp1b	APN	2	41,361,043 (GRCm39)	missense	possibly damaging	0.92
IGL03251:Lrp1b	APN	2	40,490,279 (GRCm39)	missense	probably benign	0.20
IGL03281:Lrp1b	APN	2	40,615,526 (GRCm39)	missense	probably benign	0.01
IGL03295:Lrp1b	APN	2	40,568,999 (GRCm39)	splice site	probably null
IGL03340:Lrp1b	APN	2	41,358,981 (GRCm39)	missense	probably damaging	0.97
IGL03391:Lrp1b	APN	2	41,185,653 (GRCm39)	missense	possibly damaging	0.95
IGL03401:Lrp1b	APN	2	41,000,790 (GRCm39)	missense	probably benign	0.18
IGL03403:Lrp1b	APN	2	40,592,836 (GRCm39)	missense	probably benign	0.16
IGL03408:Lrp1b	APN	2	40,748,594 (GRCm39)	missense	probably damaging	0.97
Fetching	UTSW	2	40,769,567 (GRCm39)	missense	probably benign	0.00
Heiden	UTSW	2	40,527,787 (GRCm39)	missense	probably benign	0.00
hither	UTSW	2	40,592,860 (GRCm39)	missense	probably benign	0.00
Roeslein	UTSW	2	40,615,919 (GRCm39)	missense	probably damaging	1.00
I2288:Lrp1b	UTSW	2	41,012,944 (GRCm39)	missense	probably damaging	0.99
I2289:Lrp1b	UTSW	2	41,012,944 (GRCm39)	missense	probably damaging	0.99
LCD18:Lrp1b	UTSW	2	42,127,574 (GRCm39)	intron	probably benign
PIT4431001:Lrp1b	UTSW	2	40,894,767 (GRCm39)	missense
PIT4585001:Lrp1b	UTSW	2	41,159,216 (GRCm39)	missense
R0022:Lrp1b	UTSW	2	40,888,050 (GRCm39)	splice site	probably benign
R0022:Lrp1b	UTSW	2	40,888,050 (GRCm39)	splice site	probably benign
R0054:Lrp1b	UTSW	2	40,632,829 (GRCm39)	missense	probably benign	0.11
R0054:Lrp1b	UTSW	2	40,632,829 (GRCm39)	missense	probably benign	0.11
R0094:Lrp1b	UTSW	2	41,172,042 (GRCm39)	unclassified	probably benign
R0102:Lrp1b	UTSW	2	41,298,997 (GRCm39)	splice site	probably benign
R0123:Lrp1b	UTSW	2	40,486,995 (GRCm39)	missense	probably damaging	1.00
R0128:Lrp1b	UTSW	2	41,401,520 (GRCm39)	missense	probably damaging	1.00
R0130:Lrp1b	UTSW	2	41,401,520 (GRCm39)	missense	probably damaging	1.00
R0134:Lrp1b	UTSW	2	40,486,995 (GRCm39)	missense	probably damaging	1.00
R0135:Lrp1b	UTSW	2	41,159,251 (GRCm39)	missense	probably damaging	0.99
R0153:Lrp1b	UTSW	2	41,013,031 (GRCm39)	missense	possibly damaging	0.92
R0178:Lrp1b	UTSW	2	40,615,919 (GRCm39)	missense	probably damaging	1.00
R0225:Lrp1b	UTSW	2	40,486,995 (GRCm39)	missense	probably damaging	1.00
R0242:Lrp1b	UTSW	2	40,888,195 (GRCm39)	missense	probably benign	0.01
R0242:Lrp1b	UTSW	2	40,888,195 (GRCm39)	missense	probably benign	0.01
R0312:Lrp1b	UTSW	2	41,172,183 (GRCm39)	missense	probably damaging	1.00
R0325:Lrp1b	UTSW	2	40,741,723 (GRCm39)	missense	probably damaging	1.00
R0330:Lrp1b	UTSW	2	40,591,773 (GRCm39)	nonsense	probably null
R0372:Lrp1b	UTSW	2	40,620,810 (GRCm39)	missense	probably benign	0.30
R0400:Lrp1b	UTSW	2	40,640,926 (GRCm39)	missense	probably benign	0.40
R0408:Lrp1b	UTSW	2	40,567,603 (GRCm39)	missense	probably damaging	1.00
R0498:Lrp1b	UTSW	2	41,348,417 (GRCm39)	missense	probably benign	0.19
R0563:Lrp1b	UTSW	2	40,640,926 (GRCm39)	missense	probably benign	0.40
R0569:Lrp1b	UTSW	2	40,779,251 (GRCm39)	missense	probably benign	0.11
R0622:Lrp1b	UTSW	2	41,618,563 (GRCm39)	critical splice donor site	probably null
R0682:Lrp1b	UTSW	2	41,185,653 (GRCm39)	missense	probably benign	0.01
R0727:Lrp1b	UTSW	2	40,640,956 (GRCm39)	missense	probably benign	0.40
R0747:Lrp1b	UTSW	2	40,760,353 (GRCm39)	missense	probably damaging	1.00
R0761:Lrp1b	UTSW	2	41,075,947 (GRCm39)	missense	probably damaging	0.99
R0905:Lrp1b	UTSW	2	41,174,197 (GRCm39)	missense	probably damaging	1.00
R0959:Lrp1b	UTSW	2	41,158,366 (GRCm39)	missense	possibly damaging	0.83
R1124:Lrp1b	UTSW	2	40,765,063 (GRCm39)	missense	probably damaging	1.00
R1158:Lrp1b	UTSW	2	40,567,506 (GRCm39)	missense	unknown
R1265:Lrp1b	UTSW	2	41,366,666 (GRCm39)	missense	probably damaging	1.00
R1276:Lrp1b	UTSW	2	41,618,588 (GRCm39)	missense	probably benign	0.35
R1277:Lrp1b	UTSW	2	40,615,957 (GRCm39)	missense	probably benign
R1282:Lrp1b	UTSW	2	40,750,773 (GRCm39)	missense	probably damaging	1.00
R1291:Lrp1b	UTSW	2	41,231,907 (GRCm39)	missense	probably benign	0.05
R1316:Lrp1b	UTSW	2	40,592,816 (GRCm39)	missense	probably benign
R1340:Lrp1b	UTSW	2	40,592,806 (GRCm39)	missense	probably benign	0.02
R1371:Lrp1b	UTSW	2	40,537,165 (GRCm39)	missense	probably damaging	1.00
R1415:Lrp1b	UTSW	2	40,519,676 (GRCm39)	missense	probably damaging	1.00
R1416:Lrp1b	UTSW	2	40,888,228 (GRCm39)	missense	probably damaging	1.00
R1417:Lrp1b	UTSW	2	40,894,653 (GRCm39)	missense	probably benign	0.14
R1465:Lrp1b	UTSW	2	41,001,071 (GRCm39)	missense	probably benign	0.00
R1465:Lrp1b	UTSW	2	41,001,071 (GRCm39)	missense	probably benign	0.00
R1467:Lrp1b	UTSW	2	40,547,368 (GRCm39)	splice site	probably benign
R1468:Lrp1b	UTSW	2	40,817,841 (GRCm39)	critical splice donor site	probably null
R1468:Lrp1b	UTSW	2	40,817,841 (GRCm39)	critical splice donor site	probably null
R1480:Lrp1b	UTSW	2	40,793,401 (GRCm39)	missense	probably damaging	1.00
R1488:Lrp1b	UTSW	2	41,392,036 (GRCm39)	missense	probably benign	0.01
R1496:Lrp1b	UTSW	2	42,213,674 (GRCm39)	missense	probably damaging	0.98
R1542:Lrp1b	UTSW	2	41,013,724 (GRCm39)	missense	probably damaging	1.00
R1571:Lrp1b	UTSW	2	41,366,658 (GRCm39)	missense	probably damaging	1.00
R1598:Lrp1b	UTSW	2	41,401,490 (GRCm39)	missense	probably damaging	1.00
R1619:Lrp1b	UTSW	2	40,587,601 (GRCm39)	missense	unknown
R1697:Lrp1b	UTSW	2	40,712,695 (GRCm39)	missense	probably damaging	0.99
R1698:Lrp1b	UTSW	2	40,741,818 (GRCm39)	nonsense	probably null
R1699:Lrp1b	UTSW	2	41,075,974 (GRCm39)	missense	possibly damaging	0.91
R1715:Lrp1b	UTSW	2	41,075,993 (GRCm39)	missense	probably damaging	1.00
R1748:Lrp1b	UTSW	2	41,618,718 (GRCm39)	missense	possibly damaging	0.56
R1756:Lrp1b	UTSW	2	41,000,837 (GRCm39)	missense	probably damaging	1.00
R1889:Lrp1b	UTSW	2	40,809,179 (GRCm39)	nonsense	probably null
R1895:Lrp1b	UTSW	2	40,555,159 (GRCm39)	missense	unknown
R1902:Lrp1b	UTSW	2	40,750,673 (GRCm39)	missense	probably damaging	1.00
R1919:Lrp1b	UTSW	2	41,618,741 (GRCm39)	missense	probably benign	0.00
R1939:Lrp1b	UTSW	2	40,587,601 (GRCm39)	missense	unknown
R1946:Lrp1b	UTSW	2	40,555,159 (GRCm39)	missense	unknown
R1954:Lrp1b	UTSW	2	40,748,453 (GRCm39)	missense	probably damaging	1.00
R1970:Lrp1b	UTSW	2	40,765,081 (GRCm39)	missense	probably damaging	1.00
R1983:Lrp1b	UTSW	2	41,401,416 (GRCm39)	critical splice donor site	probably null
R2029:Lrp1b	UTSW	2	41,231,861 (GRCm39)	missense	probably benign	0.02
R2054:Lrp1b	UTSW	2	40,587,494 (GRCm39)	missense	unknown
R2108:Lrp1b	UTSW	2	41,000,769 (GRCm39)	missense	probably damaging	1.00
R2158:Lrp1b	UTSW	2	40,769,567 (GRCm39)	missense	probably benign	0.00
R2168:Lrp1b	UTSW	2	41,265,858 (GRCm39)	missense	probably damaging	1.00
R2184:Lrp1b	UTSW	2	40,620,714 (GRCm39)	missense	probably benign
R2188:Lrp1b	UTSW	2	41,298,971 (GRCm39)	missense	probably benign	0.25
R2200:Lrp1b	UTSW	2	41,174,177 (GRCm39)	missense	probably benign	0.43
R2342:Lrp1b	UTSW	2	40,809,208 (GRCm39)	missense	possibly damaging	0.89
R2421:Lrp1b	UTSW	2	40,772,145 (GRCm39)	splice site	probably benign
R2656:Lrp1b	UTSW	2	41,401,593 (GRCm39)	missense	probably damaging	0.99
R2864:Lrp1b	UTSW	2	40,765,007 (GRCm39)	missense	possibly damaging	0.92
R2874:Lrp1b	UTSW	2	40,741,705 (GRCm39)	missense	probably damaging	1.00
R2911:Lrp1b	UTSW	2	41,396,704 (GRCm39)	missense	probably benign	0.00
R2919:Lrp1b	UTSW	2	41,660,911 (GRCm39)	missense	probably damaging	1.00
R3027:Lrp1b	UTSW	2	40,760,283 (GRCm39)	missense	probably benign	0.33
R3083:Lrp1b	UTSW	2	40,490,336 (GRCm39)	missense	probably damaging	0.99
R3545:Lrp1b	UTSW	2	40,490,300 (GRCm39)	missense	probably damaging	1.00
R3546:Lrp1b	UTSW	2	40,490,300 (GRCm39)	missense	probably damaging	1.00
R3547:Lrp1b	UTSW	2	40,490,300 (GRCm39)	missense	probably damaging	1.00
R3709:Lrp1b	UTSW	2	40,587,454 (GRCm39)	missense	unknown
R3817:Lrp1b	UTSW	2	40,766,670 (GRCm39)	missense	probably damaging	1.00
R3876:Lrp1b	UTSW	2	41,335,206 (GRCm39)	missense	probably damaging	1.00
R3877:Lrp1b	UTSW	2	41,335,206 (GRCm39)	missense	probably damaging	1.00
R3896:Lrp1b	UTSW	2	40,812,440 (GRCm39)	splice site	probably null
R3901:Lrp1b	UTSW	2	40,712,707 (GRCm39)	missense	probably damaging	1.00
R3915:Lrp1b	UTSW	2	41,339,248 (GRCm39)	missense	probably damaging	1.00
R3922:Lrp1b	UTSW	2	40,567,593 (GRCm39)	missense	unknown
R3964:Lrp1b	UTSW	2	41,202,482 (GRCm39)	splice site	probably benign
R4013:Lrp1b	UTSW	2	40,692,996 (GRCm39)	missense	possibly damaging	0.66
R4014:Lrp1b	UTSW	2	40,692,996 (GRCm39)	missense	possibly damaging	0.66
R4015:Lrp1b	UTSW	2	40,692,996 (GRCm39)	missense	possibly damaging	0.66
R4017:Lrp1b	UTSW	2	40,692,996 (GRCm39)	missense	possibly damaging	0.66
R4031:Lrp1b	UTSW	2	40,592,860 (GRCm39)	missense	probably benign	0.00
R4095:Lrp1b	UTSW	2	41,339,203 (GRCm39)	missense	probably benign	0.03
R4108:Lrp1b	UTSW	2	40,555,099 (GRCm39)	missense	unknown
R4176:Lrp1b	UTSW	2	41,298,405 (GRCm39)	missense	probably damaging	1.00
R4181:Lrp1b	UTSW	2	40,501,446 (GRCm39)	missense	probably damaging	1.00
R4359:Lrp1b	UTSW	2	40,793,077 (GRCm39)	missense	probably damaging	1.00
R4410:Lrp1b	UTSW	2	40,555,094 (GRCm39)	missense	possibly damaging	0.96
R4416:Lrp1b	UTSW	2	40,553,679 (GRCm39)	missense	unknown
R4489:Lrp1b	UTSW	2	40,551,501 (GRCm39)	unclassified	probably benign
R4577:Lrp1b	UTSW	2	40,711,731 (GRCm39)	missense	probably damaging	1.00
R4623:Lrp1b	UTSW	2	41,136,033 (GRCm39)	missense	probably damaging	1.00
R4677:Lrp1b	UTSW	2	40,691,496 (GRCm39)	missense	probably damaging	1.00
R4684:Lrp1b	UTSW	2	40,812,316 (GRCm39)	missense	probably benign	0.44
R4714:Lrp1b	UTSW	2	41,000,771 (GRCm39)	missense	possibly damaging	0.90
R4721:Lrp1b	UTSW	2	40,605,381 (GRCm39)	splice site	probably null
R4755:Lrp1b	UTSW	2	41,361,028 (GRCm39)	missense	probably benign
R4755:Lrp1b	UTSW	2	41,159,285 (GRCm39)	missense	probably benign	0.07
R4774:Lrp1b	UTSW	2	40,551,544 (GRCm39)	missense	probably null	1.00
R4854:Lrp1b	UTSW	2	41,001,089 (GRCm39)	missense	probably damaging	1.00
R4880:Lrp1b	UTSW	2	41,660,931 (GRCm39)	missense	probably benign	0.07
R4885:Lrp1b	UTSW	2	41,358,905 (GRCm39)	missense	probably benign
R4901:Lrp1b	UTSW	2	40,711,657 (GRCm39)	missense	probably damaging	1.00
R4919:Lrp1b	UTSW	2	40,537,246 (GRCm39)	missense	probably benign	0.25
R4935:Lrp1b	UTSW	2	41,388,405 (GRCm39)	missense	probably benign	0.01
R4937:Lrp1b	UTSW	2	40,692,897 (GRCm39)	splice site	probably null
R4967:Lrp1b	UTSW	2	41,678,986 (GRCm39)	missense	probably damaging	1.00
R4968:Lrp1b	UTSW	2	41,679,074 (GRCm39)	missense	probably damaging	1.00
R4968:Lrp1b	UTSW	2	40,592,719 (GRCm39)	splice site	probably null
R5155:Lrp1b	UTSW	2	41,618,634 (GRCm39)	splice site	probably null
R5221:Lrp1b	UTSW	2	41,002,994 (GRCm39)	missense	possibly damaging	0.79
R5224:Lrp1b	UTSW	2	41,000,852 (GRCm39)	missense	possibly damaging	0.61
R5227:Lrp1b	UTSW	2	40,741,805 (GRCm39)	missense	possibly damaging	0.95
R5246:Lrp1b	UTSW	2	41,360,952 (GRCm39)	critical splice donor site	probably null
R5263:Lrp1b	UTSW	2	41,850,691 (GRCm39)	missense	probably damaging	1.00
R5274:Lrp1b	UTSW	2	41,234,456 (GRCm39)	missense	probably null	1.00
R5291:Lrp1b	UTSW	2	40,793,015 (GRCm39)	missense	probably damaging	1.00
R5362:Lrp1b	UTSW	2	41,265,914 (GRCm39)	missense	probably damaging	1.00
R5365:Lrp1b	UTSW	2	40,537,137 (GRCm39)	missense	possibly damaging	0.55
R5369:Lrp1b	UTSW	2	40,894,625 (GRCm39)	nonsense	probably null
R5419:Lrp1b	UTSW	2	40,620,716 (GRCm39)	nonsense	probably null
R5434:Lrp1b	UTSW	2	41,660,880 (GRCm39)	missense	probably damaging	0.96
R5452:Lrp1b	UTSW	2	40,812,328 (GRCm39)	missense	probably damaging	1.00
R5453:Lrp1b	UTSW	2	41,172,249 (GRCm39)	missense	probably damaging	1.00
R5496:Lrp1b	UTSW	2	40,817,985 (GRCm39)	missense	probably benign	0.02
R5524:Lrp1b	UTSW	2	41,000,900 (GRCm39)	missense	probably damaging	1.00
R5538:Lrp1b	UTSW	2	40,587,486 (GRCm39)	missense	unknown
R5571:Lrp1b	UTSW	2	41,298,354 (GRCm39)	missense	probably damaging	0.97
R5577:Lrp1b	UTSW	2	40,765,135 (GRCm39)	missense	possibly damaging	0.70
R5609:Lrp1b	UTSW	2	41,231,807 (GRCm39)	missense	probably damaging	1.00
R5635:Lrp1b	UTSW	2	42,542,834 (GRCm39)	utr 5 prime	probably benign
R5669:Lrp1b	UTSW	2	41,001,050 (GRCm39)	missense	probably damaging	1.00
R5672:Lrp1b	UTSW	2	41,231,771 (GRCm39)	missense	probably benign	0.01
R5690:Lrp1b	UTSW	2	40,640,906 (GRCm39)	splice site	probably null
R5752:Lrp1b	UTSW	2	41,185,624 (GRCm39)	missense	probably damaging	1.00
R5853:Lrp1b	UTSW	2	40,553,738 (GRCm39)	missense	unknown
R5869:Lrp1b	UTSW	2	40,894,615 (GRCm39)	missense	probably damaging	0.98
R5880:Lrp1b	UTSW	2	41,231,826 (GRCm39)	missense	probably benign	0.23
R5887:Lrp1b	UTSW	2	40,711,719 (GRCm39)	missense	possibly damaging	0.91
R5893:Lrp1b	UTSW	2	40,491,599 (GRCm39)	missense	probably damaging	1.00
R5894:Lrp1b	UTSW	2	41,388,233 (GRCm39)	missense	probably benign	0.11
R6019:Lrp1b	UTSW	2	41,192,982 (GRCm39)	missense	probably damaging	1.00
R6019:Lrp1b	UTSW	2	41,366,821 (GRCm39)	missense	probably damaging	1.00
R6021:Lrp1b	UTSW	2	41,234,439 (GRCm39)	missense	probably benign	0.02
R6045:Lrp1b	UTSW	2	40,591,825 (GRCm39)	missense	unknown
R6047:Lrp1b	UTSW	2	40,527,787 (GRCm39)	missense	probably benign	0.00
R6060:Lrp1b	UTSW	2	40,640,946 (GRCm39)	missense
R6063:Lrp1b	UTSW	2	41,174,156 (GRCm39)	nonsense	probably null
R6090:Lrp1b	UTSW	2	41,075,880 (GRCm39)	critical splice donor site	probably null
R6112:Lrp1b	UTSW	2	41,231,894 (GRCm39)	missense	probably benign	0.14
R6128:Lrp1b	UTSW	2	40,750,667 (GRCm39)	missense	probably benign
R6149:Lrp1b	UTSW	2	40,765,165 (GRCm39)	splice site	probably null
R6174:Lrp1b	UTSW	2	41,339,275 (GRCm39)	missense	probably benign
R6177:Lrp1b	UTSW	2	41,013,748 (GRCm39)	splice site	probably null
R6257:Lrp1b	UTSW	2	40,486,981 (GRCm39)	splice site	probably null
R6267:Lrp1b	UTSW	2	40,547,537 (GRCm39)	missense	probably benign	0.00
R6268:Lrp1b	UTSW	2	40,711,729 (GRCm39)	missense	probably benign	0.01
R6331:Lrp1b	UTSW	2	40,693,221 (GRCm39)	missense	probably damaging	1.00
R6334:Lrp1b	UTSW	2	41,679,045 (GRCm39)	missense	probably benign
R6359:Lrp1b	UTSW	2	41,185,608 (GRCm39)	missense	probably damaging	1.00
R6371:Lrp1b	UTSW	2	40,741,666 (GRCm39)	missense	possibly damaging	0.61
R6421:Lrp1b	UTSW	2	40,779,282 (GRCm39)	missense	probably damaging	1.00
R6524:Lrp1b	UTSW	2	40,741,816 (GRCm39)	missense	possibly damaging	0.95
R6616:Lrp1b	UTSW	2	40,589,643 (GRCm39)	missense	unknown
R6632:Lrp1b	UTSW	2	40,615,454 (GRCm39)	missense	probably benign	0.23
R6656:Lrp1b	UTSW	2	40,527,876 (GRCm39)	nonsense	probably null
R6698:Lrp1b	UTSW	2	41,192,958 (GRCm39)	missense	probably damaging	1.00
R6741:Lrp1b	UTSW	2	41,136,001 (GRCm39)	missense	possibly damaging	0.82
R6742:Lrp1b	UTSW	2	41,361,132 (GRCm39)	missense	probably benign	0.31
R6811:Lrp1b	UTSW	2	41,339,206 (GRCm39)	missense	probably benign	0.01
R6811:Lrp1b	UTSW	2	40,605,512 (GRCm39)	splice site	probably null
R6855:Lrp1b	UTSW	2	40,518,708 (GRCm39)	missense	possibly damaging	0.66
R6888:Lrp1b	UTSW	2	41,361,138 (GRCm39)	missense	probably benign	0.18
R6946:Lrp1b	UTSW	2	40,587,451 (GRCm39)	missense	probably benign
R6984:Lrp1b	UTSW	2	40,712,640 (GRCm39)	missense	probably damaging	0.97
R7026:Lrp1b	UTSW	2	41,159,234 (GRCm39)	missense	probably damaging	1.00
R7028:Lrp1b	UTSW	2	41,136,023 (GRCm39)	missense	probably benign	0.45
R7036:Lrp1b	UTSW	2	41,002,354 (GRCm39)	missense	possibly damaging	0.89
R7043:Lrp1b	UTSW	2	40,812,426 (GRCm39)	missense	possibly damaging	0.84
R7071:Lrp1b	UTSW	2	41,298,276 (GRCm39)	missense
R7077:Lrp1b	UTSW	2	41,660,858 (GRCm39)	missense
R7115:Lrp1b	UTSW	2	40,888,247 (GRCm39)	missense
R7143:Lrp1b	UTSW	2	41,202,655 (GRCm39)	missense
R7146:Lrp1b	UTSW	2	41,266,006 (GRCm39)	nonsense	probably null
R7149:Lrp1b	UTSW	2	40,527,872 (GRCm39)	missense
R7185:Lrp1b	UTSW	2	40,691,524 (GRCm39)	critical splice acceptor site	probably null
R7239:Lrp1b	UTSW	2	40,894,725 (GRCm39)	missense
R7247:Lrp1b	UTSW	2	41,159,224 (GRCm39)	missense
R7331:Lrp1b	UTSW	2	40,553,622 (GRCm39)	splice site	probably null
R7369:Lrp1b	UTSW	2	41,172,051 (GRCm39)	missense
R7378:Lrp1b	UTSW	2	41,185,681 (GRCm39)	missense
R7381:Lrp1b	UTSW	2	40,692,929 (GRCm39)	missense
R7406:Lrp1b	UTSW	2	41,266,030 (GRCm39)	critical splice acceptor site	probably null
R7437:Lrp1b	UTSW	2	40,712,658 (GRCm39)	missense
R7437:Lrp1b	UTSW	2	40,712,657 (GRCm39)	missense
R7446:Lrp1b	UTSW	2	41,561,069 (GRCm39)	missense
R7460:Lrp1b	UTSW	2	40,488,478 (GRCm39)	missense
R7462:Lrp1b	UTSW	2	41,003,041 (GRCm39)	missense
R7475:Lrp1b	UTSW	2	41,234,588 (GRCm39)	missense
R7479:Lrp1b	UTSW	2	40,691,517 (GRCm39)	missense
R7523:Lrp1b	UTSW	2	41,401,473 (GRCm39)	missense
R7525:Lrp1b	UTSW	2	40,547,428 (GRCm39)	missense
R7549:Lrp1b	UTSW	2	40,765,134 (GRCm39)	missense
R7552:Lrp1b	UTSW	2	40,567,582 (GRCm39)	missense
R7558:Lrp1b	UTSW	2	41,231,948 (GRCm39)	missense
R7587:Lrp1b	UTSW	2	40,620,729 (GRCm39)	missense
R7599:Lrp1b	UTSW	2	40,551,561 (GRCm39)	missense
R7635:Lrp1b	UTSW	2	41,013,609 (GRCm39)	critical splice donor site	probably null
R7663:Lrp1b	UTSW	2	42,543,047 (GRCm39)	unclassified	probably benign
R7674:Lrp1b	UTSW	2	42,542,921 (GRCm39)	start gained	probably benign
R7681:Lrp1b	UTSW	2	40,765,011 (GRCm39)	nonsense	probably null
R7703:Lrp1b	UTSW	2	41,000,798 (GRCm39)	missense
R7742:Lrp1b	UTSW	2	40,712,641 (GRCm39)	missense
R7767:Lrp1b	UTSW	2	40,691,517 (GRCm39)	missense
R7829:Lrp1b	UTSW	2	40,793,460 (GRCm39)	nonsense	probably null
R7861:Lrp1b	UTSW	2	40,587,570 (GRCm39)	missense
R7868:Lrp1b	UTSW	2	41,339,246 (GRCm39)	missense
R7883:Lrp1b	UTSW	2	40,555,141 (GRCm39)	missense
R7956:Lrp1b	UTSW	2	41,172,161 (GRCm39)	splice site	probably null
R7963:Lrp1b	UTSW	2	40,817,947 (GRCm39)	missense
R7964:Lrp1b	UTSW	2	40,488,523 (GRCm39)	missense
R8035:Lrp1b	UTSW	2	40,750,667 (GRCm39)	missense
R8046:Lrp1b	UTSW	2	41,159,199 (GRCm39)	missense
R8128:Lrp1b	UTSW	2	41,159,248 (GRCm39)	missense	probably null
R8234:Lrp1b	UTSW	2	41,202,668 (GRCm39)	missense
R8237:Lrp1b	UTSW	2	40,741,786 (GRCm39)	missense
R8244:Lrp1b	UTSW	2	41,396,794 (GRCm39)	missense
R8370:Lrp1b	UTSW	2	40,888,117 (GRCm39)	missense
R8395:Lrp1b	UTSW	2	40,547,411 (GRCm39)	missense
R8398:Lrp1b	UTSW	2	40,591,819 (GRCm39)	missense
R8421:Lrp1b	UTSW	2	40,615,435 (GRCm39)	missense
R8426:Lrp1b	UTSW	2	41,388,318 (GRCm39)	missense
R8443:Lrp1b	UTSW	2	41,265,867 (GRCm39)	nonsense	probably null
R8444:Lrp1b	UTSW	2	40,760,272 (GRCm39)	missense
R8486:Lrp1b	UTSW	2	41,618,702 (GRCm39)	missense	probably damaging	1.00
R8500:Lrp1b	UTSW	2	41,396,791 (GRCm39)	missense	probably benign	0.12
R8507:Lrp1b	UTSW	2	41,298,387 (GRCm39)	missense
R8552:Lrp1b	UTSW	2	41,298,993 (GRCm39)	missense	probably benign	0.00
R8554:Lrp1b	UTSW	2	41,234,495 (GRCm39)	missense	probably benign	0.28
R8669:Lrp1b	UTSW	2	41,172,047 (GRCm39)	critical splice donor site	probably null
R8699:Lrp1b	UTSW	2	41,172,207 (GRCm39)	missense
R8796:Lrp1b	UTSW	2	40,793,426 (GRCm39)	missense
R8815:Lrp1b	UTSW	2	40,555,171 (GRCm39)	missense
R8842:Lrp1b	UTSW	2	41,158,417 (GRCm39)	missense
R8858:Lrp1b	UTSW	2	41,560,827 (GRCm39)	intron	probably benign
R8864:Lrp1b	UTSW	2	41,002,718 (GRCm39)	missense
R8918:Lrp1b	UTSW	2	40,615,893 (GRCm39)	missense
R8920:Lrp1b	UTSW	2	42,213,610 (GRCm39)	missense
R8963:Lrp1b	UTSW	2	40,888,196 (GRCm39)	missense	probably benign	0.28
R8971:Lrp1b	UTSW	2	41,325,640 (GRCm39)	missense
R9007:Lrp1b	UTSW	2	40,587,564 (GRCm39)	missense
R9042:Lrp1b	UTSW	2	41,392,029 (GRCm39)	missense
R9053:Lrp1b	UTSW	2	40,748,501 (GRCm39)	missense
R9063:Lrp1b	UTSW	2	41,231,838 (GRCm39)	missense
R9072:Lrp1b	UTSW	2	40,615,457 (GRCm39)	nonsense	probably null
R9105:Lrp1b	UTSW	2	41,396,803 (GRCm39)	missense
R9131:Lrp1b	UTSW	2	40,589,590 (GRCm39)	nonsense	probably null
R9226:Lrp1b	UTSW	2	41,401,460 (GRCm39)	missense
R9245:Lrp1b	UTSW	2	40,488,456 (GRCm39)	missense
R9275:Lrp1b	UTSW	2	40,487,076 (GRCm39)	missense
R9278:Lrp1b	UTSW	2	40,487,076 (GRCm39)	missense
R9303:Lrp1b	UTSW	2	41,618,574 (GRCm39)	missense
R9305:Lrp1b	UTSW	2	41,618,574 (GRCm39)	missense
R9306:Lrp1b	UTSW	2	40,518,762 (GRCm39)	missense	possibly damaging	0.66
R9320:Lrp1b	UTSW	2	41,335,111 (GRCm39)	critical splice donor site	probably null
R9330:Lrp1b	UTSW	2	41,012,993 (GRCm39)	missense
R9352:Lrp1b	UTSW	2	40,748,438 (GRCm39)	missense
R9386:Lrp1b	UTSW	2	41,013,640 (GRCm39)	missense
R9397:Lrp1b	UTSW	2	40,640,922 (GRCm39)	missense
R9444:Lrp1b	UTSW	2	41,013,730 (GRCm39)	missense
R9452:Lrp1b	UTSW	2	41,850,726 (GRCm39)	nonsense	probably null
R9474:Lrp1b	UTSW	2	40,491,599 (GRCm39)	missense	probably damaging	1.00
R9501:Lrp1b	UTSW	2	41,172,247 (GRCm39)	missense
R9523:Lrp1b	UTSW	2	41,660,978 (GRCm39)	missense
R9541:Lrp1b	UTSW	2	41,234,600 (GRCm39)	missense
R9555:Lrp1b	UTSW	2	40,748,438 (GRCm39)	missense
R9555:Lrp1b	UTSW	2	40,741,693 (GRCm39)	missense
R9563:Lrp1b	UTSW	2	41,185,711 (GRCm39)	missense
R9568:Lrp1b	UTSW	2	40,569,227 (GRCm39)	missense
R9622:Lrp1b	UTSW	2	40,779,354 (GRCm39)	nonsense	probably null
R9623:Lrp1b	UTSW	2	41,366,648 (GRCm39)	missense
R9634:Lrp1b	UTSW	2	41,135,951 (GRCm39)	critical splice donor site	probably null
R9640:Lrp1b	UTSW	2	41,078,929 (GRCm39)	missense
R9664:Lrp1b	UTSW	2	40,765,004 (GRCm39)	missense
R9668:Lrp1b	UTSW	2	41,075,982 (GRCm39)	missense
R9672:Lrp1b	UTSW	2	40,779,291 (GRCm39)	missense
R9717:Lrp1b	UTSW	2	41,158,395 (GRCm39)	missense
R9741:Lrp1b	UTSW	2	41,002,300 (GRCm39)	missense
RF018:Lrp1b	UTSW	2	41,000,919 (GRCm39)	missense
RF020:Lrp1b	UTSW	2	41,660,858 (GRCm39)	missense
V1662:Lrp1b	UTSW	2	41,012,944 (GRCm39)	missense	probably damaging	0.99
X0028:Lrp1b	UTSW	2	41,361,157 (GRCm39)	missense	probably damaging	1.00
X0064:Lrp1b	UTSW	2	41,392,055 (GRCm39)	missense	probably damaging	1.00
Z1176:Lrp1b	UTSW	2	40,812,395 (GRCm39)	missense
Z1176:Lrp1b	UTSW	2	40,587,594 (GRCm39)	missense
Z1176:Lrp1b	UTSW	2	40,567,518 (GRCm39)	missense
Z1176:Lrp1b	UTSW	2	41,618,722 (GRCm39)	missense
Z1177:Lrp1b	UTSW	2	41,078,860 (GRCm39)	missense
Z1177:Lrp1b	UTSW	2	40,527,761 (GRCm39)	missense
Z1188:Lrp1b	UTSW	2	40,640,946 (GRCm39)	missense

Predicted Primers

PCR Primer
(F):5'- GGTAAGCACTCCAGTCATTTTATC -3'
(R):5'- TGCTGTGCTATGCATTGACG -3'

Sequencing Primer
(F):5'- GCACTCCAGTCATTTTATCCTTTAAG -3'
(R):5'- CTATGCATTGACGTTGTAGTTAGACC -3'

Posted On

2021-03-08