Incidental Mutation 'R8765:Ciz1'
| ID |
667795 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ciz1
|
| Ensembl Gene |
ENSMUSG00000039205 |
| Gene Name |
CDKN1A interacting zinc finger protein 1 |
| Synonyms |
0610038H21Rik, 2900056O04Rik |
| MMRRC Submission |
068599-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.128)
|
| Stock # |
R8765 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
32252724-32268311 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 32260895 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 269
(K269E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000048428
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048964]
[ENSMUST00000113331]
[ENSMUST00000113332]
[ENSMUST00000113334]
[ENSMUST00000113338]
[ENSMUST00000125818]
[ENSMUST00000131152]
[ENSMUST00000132028]
[ENSMUST00000136079]
|
| AlphaFold |
Q8VEH2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000048964
AA Change: K269E
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000048428
Gene: ENSMUSG00000039205
AA Change: K269E
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
245 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
361 |
390 |
N/A |
INTRINSIC |
|
ZnF_U1
|
534 |
568 |
1.23e-1 |
SMART |
|
ZnF_C2H2
|
537 |
561 |
1.99e0 |
SMART |
|
ZnF_U1
|
626 |
660 |
2.08e-1 |
SMART |
|
ZnF_C2H2
|
629 |
653 |
3.02e0 |
SMART |
|
low complexity region
|
689 |
709 |
N/A |
INTRINSIC |
|
ZnF_U1
|
744 |
779 |
1.43e-4 |
SMART |
|
ZnF_C2H2
|
747 |
772 |
9.56e1 |
SMART |
|
low complexity region
|
823 |
845 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113331
AA Change: K245E
PolyPhen 2
Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000108957
Gene: ENSMUSG00000039205
AA Change: K245E
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
104 |
116 |
N/A |
INTRINSIC |
|
low complexity region
|
221 |
232 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
252 |
284 |
9.48e-5 |
PROSPERO |
|
internal_repeat_2
|
301 |
333 |
9.48e-5 |
PROSPERO |
|
low complexity region
|
337 |
366 |
N/A |
INTRINSIC |
|
ZnF_U1
|
510 |
544 |
1.23e-1 |
SMART |
|
ZnF_C2H2
|
513 |
537 |
1.99e0 |
SMART |
|
ZnF_U1
|
602 |
636 |
2.08e-1 |
SMART |
|
ZnF_C2H2
|
605 |
629 |
3.02e0 |
SMART |
|
low complexity region
|
665 |
685 |
N/A |
INTRINSIC |
|
ZnF_U1
|
720 |
755 |
1.43e-4 |
SMART |
|
ZnF_C2H2
|
723 |
748 |
9.56e1 |
SMART |
|
low complexity region
|
799 |
821 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113332
AA Change: K264E
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000108958
Gene: ENSMUSG00000039205
AA Change: K264E
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
240 |
251 |
N/A |
INTRINSIC |
|
ZnF_U1
|
480 |
514 |
1.23e-1 |
SMART |
|
ZnF_C2H2
|
483 |
507 |
1.99e0 |
SMART |
|
Blast:ZnF_U1
|
543 |
570 |
2e-6 |
BLAST |
|
ZnF_U1
|
572 |
606 |
2.08e-1 |
SMART |
|
ZnF_C2H2
|
575 |
599 |
3.02e0 |
SMART |
|
low complexity region
|
635 |
655 |
N/A |
INTRINSIC |
|
ZnF_U1
|
690 |
725 |
1.43e-4 |
SMART |
|
ZnF_C2H2
|
693 |
718 |
9.56e1 |
SMART |
|
low complexity region
|
769 |
791 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113334
AA Change: K269E
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000108960
Gene: ENSMUSG00000039205
AA Change: K269E
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
245 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
361 |
390 |
N/A |
INTRINSIC |
|
ZnF_U1
|
534 |
568 |
1.23e-1 |
SMART |
|
ZnF_C2H2
|
537 |
561 |
1.99e0 |
SMART |
|
ZnF_U1
|
626 |
660 |
2.08e-1 |
SMART |
|
ZnF_C2H2
|
629 |
653 |
3.02e0 |
SMART |
|
low complexity region
|
689 |
709 |
N/A |
INTRINSIC |
|
ZnF_U1
|
744 |
779 |
1.43e-4 |
SMART |
|
ZnF_C2H2
|
747 |
772 |
9.56e1 |
SMART |
|
low complexity region
|
823 |
845 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113338
AA Change: K269E
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000108964
Gene: ENSMUSG00000039205
AA Change: K269E
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
245 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
361 |
390 |
N/A |
INTRINSIC |
|
ZnF_U1
|
534 |
568 |
1.23e-1 |
SMART |
|
ZnF_C2H2
|
537 |
561 |
1.99e0 |
SMART |
|
ZnF_U1
|
626 |
660 |
2.08e-1 |
SMART |
|
ZnF_C2H2
|
629 |
653 |
3.02e0 |
SMART |
|
low complexity region
|
689 |
709 |
N/A |
INTRINSIC |
|
ZnF_U1
|
744 |
779 |
1.43e-4 |
SMART |
|
ZnF_C2H2
|
747 |
772 |
9.56e1 |
SMART |
|
low complexity region
|
823 |
845 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125482
|
| SMART Domains |
Protein: ENSMUSP00000120019
Gene: ENSMUSG00000039205
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
216 |
240 |
1.99e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125818
|
| SMART Domains |
Protein: ENSMUSP00000117937
Gene: ENSMUSG00000039205
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:ZnF_U1
|
4 |
31 |
3e-6 |
BLAST |
|
ZnF_U1
|
33 |
67 |
2.08e-1 |
SMART |
|
ZnF_C2H2
|
36 |
60 |
3.02e0 |
SMART |
|
low complexity region
|
96 |
116 |
N/A |
INTRINSIC |
|
ZnF_U1
|
151 |
186 |
1.43e-4 |
SMART |
|
ZnF_C2H2
|
154 |
179 |
9.56e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131152
|
| SMART Domains |
Protein: ENSMUSP00000141211
Gene: ENSMUSG00000039205
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132028
|
| SMART Domains |
Protein: ENSMUSP00000120295
Gene: ENSMUSG00000039205
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
140 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000136079
|
| SMART Domains |
Protein: ENSMUSP00000116812
Gene: ENSMUSG00000039205
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
85 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
140 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000139637
AA Change: K108E
PolyPhen 2
Score 0.944 (Sensitivity: 0.80; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000122469
Gene: ENSMUSG00000039205
AA Change: K108E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
85 |
96 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
230 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000151806
AA Change: K93E
PolyPhen 2
Score 0.659 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000119429
Gene: ENSMUSG00000039205
AA Change: K93E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
81 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
100% (71/71) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
PHENOTYPE: Mice hoomozygous for a knock-out allele exhibit decreased body size and gender specific effects on motor phenotypes. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
G |
A |
2: 68,566,956 (GRCm39) |
D452N |
possibly damaging |
Het |
| Actr1a |
G |
T |
19: 46,372,787 (GRCm39) |
|
probably benign |
Het |
| Alox15 |
A |
G |
11: 70,240,819 (GRCm39) |
V187A |
probably benign |
Het |
| Alpk1 |
A |
T |
3: 127,466,118 (GRCm39) |
N1129K |
probably damaging |
Het |
| Angptl1 |
A |
G |
1: 156,684,727 (GRCm39) |
N299D |
probably benign |
Het |
| Ank2 |
T |
C |
3: 126,850,731 (GRCm39) |
T128A |
possibly damaging |
Het |
| Armh4 |
C |
T |
14: 49,920,100 (GRCm39) |
R743K |
probably damaging |
Het |
| Arsj |
G |
A |
3: 126,232,781 (GRCm39) |
R509K |
probably benign |
Het |
| Atp6v0a2 |
G |
A |
5: 124,793,534 (GRCm39) |
M630I |
probably damaging |
Het |
| BC107364 |
T |
C |
3: 96,341,751 (GRCm39) |
H122R |
unknown |
Het |
| Bdh2 |
T |
C |
3: 134,996,841 (GRCm39) |
M112T |
probably benign |
Het |
| C1qtnf3 |
G |
A |
15: 10,952,843 (GRCm39) |
|
probably null |
Het |
| Cables1 |
T |
C |
18: 12,056,422 (GRCm39) |
L326P |
probably benign |
Het |
| Cacna1c |
C |
A |
6: 118,580,844 (GRCm39) |
A1769S |
|
Het |
| Cacna2d2 |
T |
C |
9: 107,394,358 (GRCm39) |
L567P |
probably damaging |
Het |
| Cacnb4 |
C |
T |
2: 52,327,001 (GRCm39) |
R399H |
probably damaging |
Het |
| Cacng4 |
A |
C |
11: 107,625,976 (GRCm39) |
I205S |
probably damaging |
Het |
| Csf1 |
A |
G |
3: 107,663,991 (GRCm39) |
V35A |
probably benign |
Het |
| Csmd1 |
G |
T |
8: 16,760,627 (GRCm39) |
Y169* |
probably null |
Het |
| Ctnna1 |
T |
A |
18: 35,384,293 (GRCm39) |
M756K |
probably damaging |
Het |
| Dnah7b |
T |
A |
1: 46,392,159 (GRCm39) |
L3840Q |
possibly damaging |
Het |
| Fabp9 |
T |
C |
3: 10,258,813 (GRCm39) |
*143W |
probably null |
Het |
| Fh1 |
C |
T |
1: 175,435,378 (GRCm39) |
|
probably benign |
Het |
| Fmo2 |
T |
C |
1: 162,707,966 (GRCm39) |
T390A |
probably benign |
Het |
| Fsip1 |
G |
T |
2: 118,082,154 (GRCm39) |
D93E |
possibly damaging |
Het |
| Golga5 |
A |
G |
12: 102,445,963 (GRCm39) |
D406G |
probably benign |
Het |
| Gucy2d |
C |
A |
7: 98,108,347 (GRCm39) |
A760E |
probably benign |
Het |
| Hax1 |
T |
C |
3: 89,904,780 (GRCm39) |
I141V |
probably benign |
Het |
| Hid1 |
T |
A |
11: 115,239,786 (GRCm39) |
|
probably null |
Het |
| Hmcn1 |
C |
T |
1: 150,556,413 (GRCm39) |
V2458I |
probably damaging |
Het |
| Igkv4-72 |
A |
G |
6: 69,203,894 (GRCm39) |
V99A |
probably benign |
Het |
| Igkv5-39 |
G |
A |
6: 69,877,915 (GRCm39) |
S16L |
probably benign |
Het |
| Ints4 |
T |
A |
7: 97,151,016 (GRCm39) |
D294E |
possibly damaging |
Het |
| Lcn11 |
A |
G |
2: 25,668,139 (GRCm39) |
Y99C |
probably damaging |
Het |
| Lrrc8b |
G |
A |
5: 105,629,133 (GRCm39) |
R493H |
probably benign |
Het |
| Mon1b |
A |
T |
8: 114,362,881 (GRCm39) |
D43V |
possibly damaging |
Het |
| Mrpl9 |
G |
A |
3: 94,355,129 (GRCm39) |
V234I |
possibly damaging |
Het |
| Nek10 |
A |
T |
14: 14,999,104 (GRCm38) |
E1034D |
probably damaging |
Het |
| Nfxl1 |
T |
C |
5: 72,686,443 (GRCm39) |
H586R |
probably benign |
Het |
| Nit2 |
T |
A |
16: 56,979,832 (GRCm39) |
D211V |
probably benign |
Het |
| Nle1 |
G |
A |
11: 82,793,882 (GRCm39) |
R385C |
probably damaging |
Het |
| Or10ak12 |
T |
C |
4: 118,666,159 (GRCm39) |
T301A |
probably benign |
Het |
| Or1i2 |
C |
T |
10: 78,448,429 (GRCm39) |
M15I |
probably benign |
Het |
| Or2a25 |
T |
C |
6: 42,889,102 (GRCm39) |
V215A |
probably benign |
Het |
| Or2ab1 |
G |
T |
11: 58,488,785 (GRCm39) |
V182F |
possibly damaging |
Het |
| Or6ae1 |
T |
C |
7: 139,742,467 (GRCm39) |
H132R |
probably benign |
Het |
| Or6c213 |
A |
G |
10: 129,574,511 (GRCm39) |
Y92H |
probably damaging |
Het |
| Pcdh10 |
T |
C |
3: 45,333,923 (GRCm39) |
I79T |
probably damaging |
Het |
| Peg10 |
A |
G |
6: 4,754,492 (GRCm39) |
D91G |
unknown |
Het |
| Plec |
C |
T |
15: 76,066,045 (GRCm39) |
A1342T |
unknown |
Het |
| Ppp2r3d |
A |
G |
9: 124,439,649 (GRCm38) |
V68A |
|
Het |
| Pramel46 |
T |
C |
5: 95,419,447 (GRCm39) |
M1V |
probably null |
Het |
| Psd3 |
A |
T |
8: 68,416,093 (GRCm39) |
D315E |
possibly damaging |
Het |
| Rack1 |
A |
G |
11: 48,694,286 (GRCm39) |
N162S |
probably benign |
Het |
| Slc12a8 |
C |
A |
16: 33,338,731 (GRCm39) |
H11Q |
possibly damaging |
Het |
| Slc44a5 |
A |
T |
3: 153,968,561 (GRCm39) |
D584V |
probably damaging |
Het |
| Spata18 |
T |
C |
5: 73,825,992 (GRCm39) |
S100P |
|
Het |
| Stap2 |
G |
T |
17: 56,310,145 (GRCm39) |
S53R |
probably damaging |
Het |
| Timeless |
T |
C |
10: 128,080,412 (GRCm39) |
|
probably null |
Het |
| Tlk1 |
A |
T |
2: 70,582,581 (GRCm39) |
S183T |
probably benign |
Het |
| Tpp2 |
T |
A |
1: 44,011,849 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
T |
2: 76,654,663 (GRCm39) |
|
probably benign |
Het |
| Uri1 |
A |
G |
7: 37,696,145 (GRCm39) |
V40A |
probably benign |
Het |
| Vmn1r15 |
T |
C |
6: 57,235,585 (GRCm39) |
V151A |
probably benign |
Het |
| Vmn1r198 |
A |
C |
13: 22,539,269 (GRCm39) |
I252L |
probably damaging |
Het |
| Vmn2r101 |
T |
A |
17: 19,809,245 (GRCm39) |
W125R |
probably damaging |
Het |
| Wdr89 |
A |
G |
12: 75,679,688 (GRCm39) |
S189P |
probably damaging |
Het |
| Zfp1006 |
T |
C |
8: 129,948,070 (GRCm39) |
D49G |
probably benign |
Het |
| Zfp873 |
T |
A |
10: 81,896,072 (GRCm39) |
C268S |
probably damaging |
Het |
| Zfp932 |
T |
A |
5: 110,154,827 (GRCm39) |
D8E |
probably benign |
Het |
| Zfyve16 |
T |
C |
13: 92,658,055 (GRCm39) |
R619G |
probably benign |
Het |
| Zswim2 |
A |
T |
2: 83,771,431 (GRCm39) |
I31N |
probably damaging |
Het |
|
| Other mutations in Ciz1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Ciz1
|
APN |
2 |
32,262,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01872:Ciz1
|
APN |
2 |
32,268,121 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R0029:Ciz1
|
UTSW |
2 |
32,261,431 (GRCm39) |
splice site |
probably benign |
|
|
R0122:Ciz1
|
UTSW |
2 |
32,261,431 (GRCm39) |
splice site |
probably benign |
|
|
R0363:Ciz1
|
UTSW |
2 |
32,267,375 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0373:Ciz1
|
UTSW |
2 |
32,257,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Ciz1
|
UTSW |
2 |
32,262,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0816:Ciz1
|
UTSW |
2 |
32,266,388 (GRCm39) |
unclassified |
probably benign |
|
|
R1255:Ciz1
|
UTSW |
2 |
32,255,888 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2116:Ciz1
|
UTSW |
2 |
32,257,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3161:Ciz1
|
UTSW |
2 |
32,260,075 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3732:Ciz1
|
UTSW |
2 |
32,257,495 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4014:Ciz1
|
UTSW |
2 |
32,264,356 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4386:Ciz1
|
UTSW |
2 |
32,260,111 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4687:Ciz1
|
UTSW |
2 |
32,257,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4786:Ciz1
|
UTSW |
2 |
32,267,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Ciz1
|
UTSW |
2 |
32,261,753 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4869:Ciz1
|
UTSW |
2 |
32,254,247 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4871:Ciz1
|
UTSW |
2 |
32,262,300 (GRCm39) |
splice site |
probably benign |
|
|
R5270:Ciz1
|
UTSW |
2 |
32,264,511 (GRCm39) |
splice site |
probably null |
|
|
R5429:Ciz1
|
UTSW |
2 |
32,266,055 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5621:Ciz1
|
UTSW |
2 |
32,261,753 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5721:Ciz1
|
UTSW |
2 |
32,266,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5805:Ciz1
|
UTSW |
2 |
32,257,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5960:Ciz1
|
UTSW |
2 |
32,261,228 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6187:Ciz1
|
UTSW |
2 |
32,260,063 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6612:Ciz1
|
UTSW |
2 |
32,267,323 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7006:Ciz1
|
UTSW |
2 |
32,261,127 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7200:Ciz1
|
UTSW |
2 |
32,254,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7498:Ciz1
|
UTSW |
2 |
32,261,761 (GRCm39) |
missense |
probably benign |
|
|
R7574:Ciz1
|
UTSW |
2 |
32,257,380 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7910:Ciz1
|
UTSW |
2 |
32,260,139 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8390:Ciz1
|
UTSW |
2 |
32,257,335 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8749:Ciz1
|
UTSW |
2 |
32,255,848 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8784:Ciz1
|
UTSW |
2 |
32,260,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8812:Ciz1
|
UTSW |
2 |
32,254,286 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8927:Ciz1
|
UTSW |
2 |
32,257,512 (GRCm39) |
nonsense |
probably null |
|
|
R8928:Ciz1
|
UTSW |
2 |
32,257,512 (GRCm39) |
nonsense |
probably null |
|
|
R9681:Ciz1
|
UTSW |
2 |
32,260,974 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9744:Ciz1
|
UTSW |
2 |
32,253,859 (GRCm39) |
missense |
unknown |
|
|
X0018:Ciz1
|
UTSW |
2 |
32,261,264 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAAAGGCCTCTGGGAAGATAG -3'
(R):5'- CTAAGTGCTCTGGAGAGGTCTG -3'
Sequencing Primer
(F):5'- CCTCTGGGAAGATAGAGCTTTG -3'
(R):5'- GTGTCTGTGCCTGCCTCAG -3'
|
| Posted On |
2021-03-08 |
Incidental Mutation