Incidental Mutation 'R8690:St18'
| ID |
668277 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St18
|
| Ensembl Gene |
ENSMUSG00000033740 |
| Gene Name |
suppression of tumorigenicity 18 |
| Synonyms |
Nzf3, Myt3 |
| MMRRC Submission |
068544-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8690 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
6557455-6931164 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 6872788 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 174
(N174K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042056
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043578]
[ENSMUST00000131494]
[ENSMUST00000139838]
[ENSMUST00000140079]
[ENSMUST00000150761]
[ENSMUST00000151281]
[ENSMUST00000163727]
|
| AlphaFold |
Q80TY4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043578
AA Change: N174K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000042056
Gene: ENSMUSG00000033740
AA Change: N174K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131494
AA Change: N174K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000117789
Gene: ENSMUSG00000033740
AA Change: N174K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132207
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139838
AA Change: N174K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000118129
Gene: ENSMUSG00000033740
AA Change: N174K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140079
AA Change: N174K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000118322
Gene: ENSMUSG00000033740
AA Change: N174K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150761
AA Change: N174K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000120298
Gene: ENSMUSG00000033740
AA Change: N174K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151281
AA Change: N174K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000122055
Gene: ENSMUSG00000033740
AA Change: N174K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163727
AA Change: N174K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000131417
Gene: ENSMUSG00000033740
AA Change: N174K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
100% (73/73) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700097O09Rik |
T |
A |
12: 55,107,957 (GRCm39) |
T81S |
possibly damaging |
Het |
| Ablim2 |
C |
T |
5: 36,030,518 (GRCm39) |
A581V |
possibly damaging |
Het |
| Acbd5 |
T |
A |
2: 22,979,710 (GRCm39) |
S210T |
probably benign |
Het |
| Adam10 |
T |
A |
9: 70,655,505 (GRCm39) |
F324L |
probably damaging |
Het |
| Ak6 |
A |
G |
13: 100,791,857 (GRCm39) |
N100S |
possibly damaging |
Het |
| Angptl3 |
G |
T |
4: 98,925,759 (GRCm39) |
V362L |
probably benign |
Het |
| Ano9 |
C |
A |
7: 140,684,220 (GRCm39) |
W514L |
probably benign |
Het |
| Asb8 |
T |
C |
15: 98,034,108 (GRCm39) |
Y149C |
probably damaging |
Het |
| Bcl6b |
C |
A |
11: 70,117,447 (GRCm39) |
A392S |
probably damaging |
Het |
| Cad |
T |
A |
5: 31,232,500 (GRCm39) |
I1855N |
possibly damaging |
Het |
| Calm5 |
G |
A |
13: 3,904,277 (GRCm39) |
G4R |
probably damaging |
Het |
| Carm1 |
T |
C |
9: 21,480,808 (GRCm39) |
V94A |
probably damaging |
Het |
| Ccnl1 |
A |
T |
3: 65,855,165 (GRCm39) |
S399R |
possibly damaging |
Het |
| Cdh17 |
T |
A |
4: 11,783,163 (GRCm39) |
I168N |
probably benign |
Het |
| Ces2g |
C |
T |
8: 105,693,605 (GRCm39) |
R429C |
probably benign |
Het |
| Chd3 |
T |
C |
11: 69,246,648 (GRCm39) |
|
probably benign |
Het |
| Cmtr2 |
T |
A |
8: 110,948,977 (GRCm39) |
M429K |
probably benign |
Het |
| Cnga1 |
T |
G |
5: 72,761,835 (GRCm39) |
I560L |
probably benign |
Het |
| Col6a5 |
A |
G |
9: 105,759,796 (GRCm39) |
Y1975H |
probably damaging |
Het |
| Copb1 |
T |
C |
7: 113,849,463 (GRCm39) |
I47V |
probably benign |
Het |
| Crbn |
G |
A |
6: 106,777,010 (GRCm39) |
|
probably benign |
Het |
| Ddx41 |
A |
G |
13: 55,680,939 (GRCm39) |
L324P |
probably damaging |
Het |
| Dhx57 |
A |
G |
17: 80,577,794 (GRCm39) |
|
probably benign |
Het |
| Dlgap2 |
A |
T |
8: 14,793,430 (GRCm39) |
I475F |
probably benign |
Het |
| Dock2 |
T |
A |
11: 34,618,287 (GRCm39) |
K110* |
probably null |
Het |
| Dpp7 |
T |
C |
2: 25,245,645 (GRCm39) |
D147G |
probably damaging |
Het |
| Dync2h1 |
G |
T |
9: 7,075,824 (GRCm39) |
D3014E |
probably damaging |
Het |
| Efcab5 |
A |
T |
11: 76,994,115 (GRCm39) |
F1291I |
probably damaging |
Het |
| Endov |
T |
A |
11: 119,382,736 (GRCm39) |
V61D |
probably benign |
Het |
| Etv3 |
C |
A |
3: 87,443,786 (GRCm39) |
P457T |
possibly damaging |
Het |
| Fam185a |
T |
A |
5: 21,638,766 (GRCm39) |
H199Q |
probably benign |
Het |
| Fat3 |
T |
A |
9: 15,878,397 (GRCm39) |
E3361D |
probably benign |
Het |
| Fbn1 |
T |
C |
2: 125,186,015 (GRCm39) |
|
probably benign |
Het |
| Gm17079 |
A |
T |
14: 51,932,787 (GRCm39) |
W37R |
|
Het |
| Gpr68 |
T |
C |
12: 100,845,292 (GRCm39) |
H84R |
probably benign |
Het |
| Gramd1b |
A |
T |
9: 40,215,674 (GRCm39) |
S725R |
probably damaging |
Het |
| Greb1 |
T |
A |
12: 16,746,548 (GRCm39) |
T1241S |
probably benign |
Het |
| Hcn4 |
T |
C |
9: 58,751,193 (GRCm39) |
M273T |
probably benign |
Het |
| Hdlbp |
A |
G |
1: 93,341,640 (GRCm39) |
V973A |
probably damaging |
Het |
| Ighv8-11 |
A |
T |
12: 115,531,164 (GRCm39) |
|
probably benign |
Het |
| Itpkb |
A |
T |
1: 180,249,346 (GRCm39) |
Q907L |
probably benign |
Het |
| Lmo7 |
T |
A |
14: 102,168,644 (GRCm39) |
N1634K |
unknown |
Het |
| Lrrk1 |
C |
A |
7: 65,952,477 (GRCm39) |
L486F |
probably benign |
Het |
| Mdfic |
G |
A |
6: 15,799,653 (GRCm39) |
C260Y |
probably damaging |
Het |
| Mdh2 |
T |
C |
5: 135,814,882 (GRCm39) |
I140T |
probably benign |
Het |
| Myo9a |
T |
C |
9: 59,782,657 (GRCm39) |
V1775A |
probably benign |
Het |
| Or1j14 |
T |
C |
2: 36,418,207 (GRCm39) |
V261A |
probably benign |
Het |
| Or51d1 |
C |
A |
7: 102,348,028 (GRCm39) |
D194E |
probably damaging |
Het |
| Or52n3 |
T |
C |
7: 104,530,762 (GRCm39) |
Y283H |
probably damaging |
Het |
| P2rx2 |
C |
T |
5: 110,490,380 (GRCm39) |
V112I |
probably damaging |
Het |
| Psme4 |
T |
A |
11: 30,787,319 (GRCm39) |
V1038E |
probably benign |
Het |
| Rab25 |
T |
A |
3: 88,452,388 (GRCm39) |
R73S |
probably damaging |
Het |
| Rab8a |
TA |
TAA |
8: 72,925,130 (GRCm39) |
|
probably null |
Het |
| Rnf213 |
T |
C |
11: 119,308,955 (GRCm39) |
Y729H |
|
Het |
| Rnf213 |
A |
G |
11: 119,332,038 (GRCm39) |
T2417A |
|
Het |
| Rnft2 |
C |
A |
5: 118,366,935 (GRCm39) |
A268S |
probably benign |
Het |
| Samhd1 |
T |
C |
2: 156,971,794 (GRCm39) |
D116G |
probably benign |
Het |
| Sema6d |
T |
A |
2: 124,506,937 (GRCm39) |
V915E |
probably benign |
Het |
| Sp140l2 |
G |
A |
1: 85,235,170 (GRCm39) |
H130Y |
probably benign |
Het |
| Srcin1 |
C |
A |
11: 97,414,368 (GRCm39) |
R1045L |
probably damaging |
Het |
| Stac3 |
G |
A |
10: 127,339,494 (GRCm39) |
C130Y |
probably damaging |
Het |
| Stum |
G |
C |
1: 180,310,740 (GRCm39) |
P52R |
probably damaging |
Het |
| Tbc1d2 |
C |
T |
4: 46,615,106 (GRCm39) |
E526K |
possibly damaging |
Het |
| Tiam1 |
A |
G |
16: 89,694,900 (GRCm39) |
S186P |
probably damaging |
Het |
| Tiparp |
G |
C |
3: 65,460,963 (GRCm39) |
V651L |
probably benign |
Het |
| Tmem19 |
C |
T |
10: 115,179,765 (GRCm39) |
G244S |
probably damaging |
Het |
| Trip11 |
A |
T |
12: 101,839,656 (GRCm39) |
V1658D |
possibly damaging |
Het |
| Ttyh3 |
A |
C |
5: 140,612,944 (GRCm39) |
Y453D |
probably damaging |
Het |
| Ttyh3 |
G |
T |
5: 140,612,945 (GRCm39) |
S452R |
probably benign |
Het |
| Ube2h |
C |
T |
6: 30,262,338 (GRCm39) |
|
probably benign |
Het |
| Zbtb4 |
T |
C |
11: 69,667,618 (GRCm39) |
S308P |
probably damaging |
Het |
| Zfyve1 |
T |
C |
12: 83,597,681 (GRCm39) |
E672G |
probably damaging |
Het |
| Zswim5 |
G |
A |
4: 116,842,002 (GRCm39) |
D861N |
probably damaging |
Het |
|
| Other mutations in St18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:St18
|
APN |
1 |
6,872,796 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00840:St18
|
APN |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01016:St18
|
APN |
1 |
6,914,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01116:St18
|
APN |
1 |
6,872,856 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01719:St18
|
APN |
1 |
6,916,020 (GRCm39) |
splice site |
probably benign |
|
|
IGL01885:St18
|
APN |
1 |
6,914,596 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02486:St18
|
APN |
1 |
6,890,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02611:St18
|
APN |
1 |
6,839,114 (GRCm39) |
splice site |
probably benign |
|
|
IGL02742:St18
|
APN |
1 |
6,872,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02953:St18
|
APN |
1 |
6,914,337 (GRCm39) |
splice site |
probably benign |
|
|
IGL02999:St18
|
APN |
1 |
6,887,829 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03092:St18
|
APN |
1 |
6,839,118 (GRCm39) |
splice site |
probably benign |
|
|
Smallish
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03055:St18
|
UTSW |
1 |
6,872,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0089:St18
|
UTSW |
1 |
6,919,172 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0257:St18
|
UTSW |
1 |
6,890,186 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0383:St18
|
UTSW |
1 |
6,873,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0588:St18
|
UTSW |
1 |
6,887,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0989:St18
|
UTSW |
1 |
6,898,105 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1068:St18
|
UTSW |
1 |
6,865,786 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1311:St18
|
UTSW |
1 |
6,915,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:St18
|
UTSW |
1 |
6,915,793 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1723:St18
|
UTSW |
1 |
6,880,909 (GRCm39) |
splice site |
probably benign |
|
|
R1926:St18
|
UTSW |
1 |
6,872,913 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1927:St18
|
UTSW |
1 |
6,872,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2035:St18
|
UTSW |
1 |
6,872,552 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:St18
|
UTSW |
1 |
6,898,195 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2139:St18
|
UTSW |
1 |
6,880,839 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2261:St18
|
UTSW |
1 |
6,915,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2300:St18
|
UTSW |
1 |
6,925,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2322:St18
|
UTSW |
1 |
6,914,348 (GRCm39) |
nonsense |
probably null |
|
|
R2846:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3738:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3739:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3772:St18
|
UTSW |
1 |
6,914,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3805:St18
|
UTSW |
1 |
6,872,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:St18
|
UTSW |
1 |
6,873,117 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4034:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4036:St18
|
UTSW |
1 |
6,898,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4407:St18
|
UTSW |
1 |
6,898,061 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4527:St18
|
UTSW |
1 |
6,925,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:St18
|
UTSW |
1 |
6,887,828 (GRCm39) |
missense |
probably benign |
|
|
R4838:St18
|
UTSW |
1 |
6,873,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5182:St18
|
UTSW |
1 |
6,887,877 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5186:St18
|
UTSW |
1 |
6,872,541 (GRCm39) |
splice site |
probably null |
|
|
R5354:St18
|
UTSW |
1 |
6,914,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5423:St18
|
UTSW |
1 |
6,872,840 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5724:St18
|
UTSW |
1 |
6,841,174 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6182:St18
|
UTSW |
1 |
6,914,342 (GRCm39) |
splice site |
probably null |
|
|
R6491:St18
|
UTSW |
1 |
6,898,209 (GRCm39) |
nonsense |
probably null |
|
|
R6503:St18
|
UTSW |
1 |
6,865,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7037:St18
|
UTSW |
1 |
6,873,260 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7098:St18
|
UTSW |
1 |
6,898,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:St18
|
UTSW |
1 |
6,929,351 (GRCm39) |
missense |
|
|
|
R7144:St18
|
UTSW |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7150:St18
|
UTSW |
1 |
6,873,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7334:St18
|
UTSW |
1 |
6,872,783 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7502:St18
|
UTSW |
1 |
6,898,194 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7729:St18
|
UTSW |
1 |
6,872,761 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7848:St18
|
UTSW |
1 |
6,927,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8088:St18
|
UTSW |
1 |
6,898,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8299:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8338:St18
|
UTSW |
1 |
6,879,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8753:St18
|
UTSW |
1 |
6,916,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8808:St18
|
UTSW |
1 |
6,880,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8880:St18
|
UTSW |
1 |
6,865,619 (GRCm39) |
nonsense |
probably null |
|
|
R9055:St18
|
UTSW |
1 |
6,873,206 (GRCm39) |
nonsense |
probably null |
|
|
R9292:St18
|
UTSW |
1 |
6,898,106 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9322:St18
|
UTSW |
1 |
6,865,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9530:St18
|
UTSW |
1 |
6,872,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9603:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9611:St18
|
UTSW |
1 |
6,873,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:St18
|
UTSW |
1 |
6,929,246 (GRCm39) |
missense |
|
|
|
R9644:St18
|
UTSW |
1 |
6,929,276 (GRCm39) |
missense |
|
|
|
R9740:St18
|
UTSW |
1 |
6,873,287 (GRCm39) |
nonsense |
probably null |
|
|
R9750:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCAATACACATGTTATCCAGAGCTC -3'
(R):5'- ATCACACCTGTTCTCACAAGGG -3'
Sequencing Primer
(F):5'- CAGAGCTCATGGTCAAATCTCTGG -3'
(R):5'- TTATCTCAGGAACTTCCAACAGGTC -3'
|
| Posted On |
2021-04-30 |
Incidental Mutation