Mutagenetix > Incidental Mutation

Incidental Mutation 'R8698:Mki67'

668851

Institutional Source

Beutler Lab

Gene Symbol

Mki67

Ensembl Gene

ENSMUSG00000031004

Gene Name

antigen identified by monoclonal antibody Ki 67

Synonyms

D630048A14Rik, Ki-67, Ki67

MMRRC Submission

068552-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.872) question?

Stock #

R8698 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

135291513-135318090 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 135296937 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 2699 (D2699G)

Ref Sequence

ENSEMBL: ENSMUSP00000033310 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033310]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000033310
AA Change: D2699G

PolyPhen 2 Score 0.872 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000033310
Gene: ENSMUSG00000031004
AA Change: D2699G

Domain	Start	End	E-Value	Type
FHA	26	76	1.03e-11	SMART
Pfam:PP1_bind	462	519	2.8e-20	PFAM
low complexity region	535	545	N/A	INTRINSIC
low complexity region	869	882	N/A	INTRINSIC
Pfam:K167R	889	982	1.5e-9	PFAM
K167R	993	1102	2.01e-39	SMART
K167R	1107	1217	1.87e-57	SMART
K167R	1228	1337	1.33e-53	SMART
K167R	1348	1451	6.57e-44	SMART
K167R	1462	1570	9.09e-38	SMART
K167R	1580	1686	5.02e-40	SMART
K167R	1697	1807	9.6e-37	SMART
K167R	1818	1926	5.94e-51	SMART
K167R	1937	2047	1.6e-56	SMART
K167R	2058	2164	4.04e-53	SMART
K167R	2175	2285	1.52e-57	SMART
K167R	2296	2407	1.78e-40	SMART
K167R	2418	2527	1.71e-42	SMART
K167R	2538	2640	7.41e-20	SMART
K167R	2642	2750	1.06e-38	SMART
K167R	2761	2872	2.1e-42	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.5%
20x: 98.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
PHENOTYPE: Mice carrying a reporter allele show expression in actively dividing cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 86 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aaas	A	G	15: 102,247,250 (GRCm39)		probably benign	Het
Adamtsl1	A	G	4: 86,306,714 (GRCm39)	N1384S	probably benign	Het
Adgre1	T	C	17: 57,709,003 (GRCm39)	S65P	probably benign	Het
Adgrl4	G	T	3: 151,203,512 (GRCm39)	C124F	probably damaging	Het
Aldh1b1	G	A	4: 45,802,942 (GRCm39)	G160D	probably damaging	Het
Alpi	T	G	1: 87,028,208 (GRCm39)	D205A	probably damaging	Het
AW146154	C	A	7: 41,129,934 (GRCm39)	R394L	probably benign	Het
Bcl10	G	A	3: 145,639,022 (GRCm39)	M221I	probably benign	Het
Brpf3	G	A	17: 29,037,436 (GRCm39)	R768H	probably damaging	Het
Cad	G	T	5: 31,234,819 (GRCm39)	R2116L	probably benign	Het
Cand2	G	T	6: 115,763,852 (GRCm39)	R258L	probably damaging	Het
Car4	A	T	11: 84,855,009 (GRCm39)	N119I	probably benign	Het
Carmil1	C	T	13: 24,220,229 (GRCm39)	G1165D	probably damaging	Het
Ccdc66	T	C	14: 27,212,647 (GRCm39)	T403A	probably benign	Het
Cdon	T	G	9: 35,398,269 (GRCm39)		probably null	Het
Cemip	T	C	7: 83,607,790 (GRCm39)	I739V	probably damaging	Het
Cep85l	A	G	10: 53,234,201 (GRCm39)	I59T	probably damaging	Het
Clec4f	A	T	6: 83,630,267 (GRCm39)	V97D	probably benign	Het
Cnot6l	A	G	5: 96,225,149 (GRCm39)	C515R	probably damaging	Het
Cntnap2	G	A	6: 47,026,156 (GRCm39)	G935D	probably damaging	Het
Cntrl	A	G	2: 35,023,974 (GRCm39)	H553R	probably damaging	Het
Cops3	A	G	11: 59,708,886 (GRCm39)	S423P	probably damaging	Het
Cox15	C	T	19: 43,739,948 (GRCm39)	R39H	probably benign	Het
Ctnna2	A	G	6: 77,630,100 (GRCm39)	V131A	probably benign	Het
Dcst2	T	A	3: 89,276,044 (GRCm39)	F392I	probably benign	Het
Decr1	A	G	4: 15,922,483 (GRCm39)		probably null	Het
Dennd3	A	C	15: 73,394,154 (GRCm39)	T60P	possibly damaging	Het
Dipk1a	A	T	5: 108,057,776 (GRCm39)	F261I	probably damaging	Het
Dmxl2	T	C	9: 54,281,953 (GRCm39)	N2859S	probably benign	Het
Dnah12	A	T	14: 26,428,418 (GRCm39)	I280F	probably benign	Het
Dnah8	A	C	17: 31,094,009 (GRCm39)	D4701A	probably damaging	Het
Dyrk1a	C	A	16: 94,487,414 (GRCm39)	H541Q	possibly damaging	Het
Eml4	T	C	17: 83,785,345 (GRCm39)	S906P	probably benign	Het
Fam169a	G	T	13: 97,243,578 (GRCm39)	V203F	probably damaging	Het
Fmn1	C	T	2: 113,260,152 (GRCm39)	L682F	unknown	Het
Gli2	T	C	1: 118,769,887 (GRCm39)	Y555C	probably damaging	Het
Gm3278	A	G	14: 16,081,505 (GRCm39)	Y130C	possibly damaging	Het
Gm8237	T	A	14: 5,863,554 (GRCm38)	Y37F	probably damaging	Het
Golga4	T	G	9: 118,385,029 (GRCm39)	L717R	probably damaging	Het
Gtpbp4	C	T	13: 9,024,249 (GRCm39)	R568H	probably benign	Het
Il1f10	A	G	2: 24,183,197 (GRCm39)	N47S	probably damaging	Het
Itga6	A	G	2: 71,673,618 (GRCm39)	H884R	probably benign	Het
Kdm1a	T	C	4: 136,286,518 (GRCm39)	K482R	probably benign	Het
Klk12	T	C	7: 43,419,113 (GRCm39)	V26A	probably benign	Het
Lrp2	T	A	2: 69,278,583 (GRCm39)	R3923S	probably benign	Het
Lrp2	C	T	2: 69,288,767 (GRCm39)	V3700M	probably benign	Het
Lrrk2	A	G	15: 91,636,400 (GRCm39)	D1458G	probably benign	Het
Mapre2	T	A	18: 24,011,090 (GRCm39)	S233T	probably benign	Het
Mthfr	T	A	4: 148,128,947 (GRCm39)	Y214*	probably null	Het
Ncoa6	A	T	2: 155,257,041 (GRCm39)	M834K	possibly damaging	Het
Neurl2	C	T	2: 164,675,054 (GRCm39)	D103N	probably benign	Het
Niban3	T	A	8: 72,060,159 (GRCm39)	I93N	unknown	Het
Or1j15	T	C	2: 36,458,915 (GRCm39)	Y102H	possibly damaging	Het
Or2ag16	A	T	7: 106,352,571 (GRCm39)	V8E	probably benign	Het
Or2b7	G	A	13: 21,739,890 (GRCm39)	L101F	probably damaging	Het
P2ry14	A	G	3: 59,022,596 (GRCm39)	V288A	possibly damaging	Het
Pde6b	G	T	5: 108,576,105 (GRCm39)	S730I	possibly damaging	Het
Pdpk1	A	T	17: 24,298,542 (GRCm39)	V496D	probably damaging	Het
Plekho2	A	T	9: 65,463,554 (GRCm39)	L432M	probably damaging	Het
Ppa2	T	C	3: 133,082,362 (GRCm39)	L151P	unknown	Het
Ppp2r3c	G	A	12: 55,328,499 (GRCm39)	T422I	probably benign	Het
Prelid3a	T	C	18: 67,610,122 (GRCm39)	S151P	probably damaging	Het
Rad21l	G	A	2: 151,487,373 (GRCm39)	P537L	probably damaging	Het
Sacs	T	A	14: 61,450,802 (GRCm39)	S4283T	probably benign	Het
Samd9l	A	T	6: 3,373,843 (GRCm39)	D1139E	probably benign	Het
Scn9a	G	T	2: 66,366,628 (GRCm39)	H718Q	probably benign	Het
Slc1a3	A	T	15: 8,668,636 (GRCm39)	I443N	probably damaging	Het
Slc22a6	A	G	19: 8,600,889 (GRCm39)	M361V	probably benign	Het
Slc8a2	A	G	7: 15,891,132 (GRCm39)	Y724C	probably damaging	Het
Slf1	A	T	13: 77,197,284 (GRCm39)	S777T	possibly damaging	Het
Sltm	T	C	9: 70,494,352 (GRCm39)	S901P	probably benign	Het
Smc1b	A	T	15: 84,997,047 (GRCm39)	H524Q	probably benign	Het
Spast	T	C	17: 74,666,341 (GRCm39)	S225P	probably benign	Het
Srsf12	C	T	4: 33,231,246 (GRCm39)	R252W	probably damaging	Het
Syne1	A	G	10: 5,179,229 (GRCm39)	L4415P	probably damaging	Het
Tmem117	A	T	15: 94,535,990 (GRCm39)	Y8F	probably benign	Het
Tmem241	T	C	18: 12,197,288 (GRCm39)	D180G	possibly damaging	Het
Tomm40	C	T	7: 19,444,890 (GRCm39)	V164I	probably benign	Het
Ttc41	T	C	10: 86,548,841 (GRCm39)	Y12H	probably benign	Het
Twnk	T	C	19: 44,996,299 (GRCm39)	V244A	probably benign	Het
Ugt1a8	T	C	1: 88,015,952 (GRCm39)	S122P	probably damaging	Het
Vmn1r78	A	G	7: 11,886,539 (GRCm39)	K50R	probably benign	Het
Vmn2r10	A	G	5: 109,151,390 (GRCm39)	F75L	probably benign	Het
Wbp4	G	T	14: 79,707,573 (GRCm39)	Y179*	probably null	Het
Zfp106	A	G	2: 120,354,600 (GRCm39)		probably null	Het
Zfp974	A	T	7: 27,610,361 (GRCm39)	C455S	possibly damaging	Het

Other mutations in Mki67

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00225:Mki67	APN	7	135,291,849 (GRCm39)	missense	probably benign	0.32
IGL00264:Mki67	APN	7	135,309,549 (GRCm39)	nonsense	probably null
IGL00328:Mki67	APN	7	135,298,424 (GRCm39)	missense	probably benign	0.03
IGL00570:Mki67	APN	7	135,309,830 (GRCm39)	missense	possibly damaging	0.88
IGL00584:Mki67	APN	7	135,297,424 (GRCm39)	missense	probably damaging	1.00
IGL00756:Mki67	APN	7	135,300,460 (GRCm39)	missense	possibly damaging	0.76
IGL01063:Mki67	APN	7	135,296,651 (GRCm39)	missense	possibly damaging	0.93
IGL01112:Mki67	APN	7	135,315,745 (GRCm39)	missense	probably damaging	1.00
IGL01360:Mki67	APN	7	135,307,505 (GRCm39)	missense	probably damaging	1.00
IGL01457:Mki67	APN	7	135,301,275 (GRCm39)	missense	probably benign	0.00
IGL01686:Mki67	APN	7	135,309,542 (GRCm39)	missense	probably benign	0.00
IGL01731:Mki67	APN	7	135,298,278 (GRCm39)	missense	probably benign	0.03
IGL01775:Mki67	APN	7	135,300,005 (GRCm39)	missense	possibly damaging	0.71
IGL01806:Mki67	APN	7	135,300,686 (GRCm39)	missense	probably damaging	0.98
IGL01860:Mki67	APN	7	135,300,686 (GRCm39)	missense	probably damaging	0.98
IGL01938:Mki67	APN	7	135,296,059 (GRCm39)	missense	probably benign	0.04
IGL02249:Mki67	APN	7	135,302,251 (GRCm39)	missense	possibly damaging	0.47
IGL02260:Mki67	APN	7	135,303,697 (GRCm39)	missense	probably benign	0.00
IGL02270:Mki67	APN	7	135,300,361 (GRCm39)	missense	probably damaging	1.00
IGL02406:Mki67	APN	7	135,300,522 (GRCm39)	missense	probably benign	0.00
IGL02499:Mki67	APN	7	135,296,056 (GRCm39)	missense	possibly damaging	0.94
IGL02655:Mki67	APN	7	135,315,748 (GRCm39)	missense	probably damaging	0.98
IGL02700:Mki67	APN	7	135,309,931 (GRCm39)	missense	probably benign	0.02
IGL03370:Mki67	APN	7	135,297,219 (GRCm39)	missense	probably benign	0.00
Advisement	UTSW	7	135,299,923 (GRCm39)	missense	probably damaging	1.00
chocotoff	UTSW	7	135,300,628 (GRCm39)	missense	possibly damaging	0.92
Godiva	UTSW	7	135,303,691 (GRCm39)	missense	probably benign	0.10
sees	UTSW	7	135,302,644 (GRCm39)	missense	possibly damaging	0.68
Whitman	UTSW	7	135,315,594 (GRCm39)	missense	probably damaging	1.00
BB003:Mki67	UTSW	7	135,298,869 (GRCm39)	missense	possibly damaging	0.91
BB013:Mki67	UTSW	7	135,298,869 (GRCm39)	missense	possibly damaging	0.91
PIT4468001:Mki67	UTSW	7	135,300,876 (GRCm39)	missense	probably benign	0.00
R0001:Mki67	UTSW	7	135,302,748 (GRCm39)	missense	probably damaging	0.99
R0001:Mki67	UTSW	7	135,300,901 (GRCm39)	missense	probably damaging	1.00
R0043:Mki67	UTSW	7	135,302,310 (GRCm39)	missense	probably benign	0.16
R0043:Mki67	UTSW	7	135,302,310 (GRCm39)	missense	probably benign	0.16
R0102:Mki67	UTSW	7	135,315,532 (GRCm39)	missense	probably benign	0.16
R0130:Mki67	UTSW	7	135,298,188 (GRCm39)	missense	probably damaging	1.00
R0149:Mki67	UTSW	7	135,300,153 (GRCm39)	missense	probably benign	0.00
R0356:Mki67	UTSW	7	135,306,135 (GRCm39)	missense	probably benign	0.34
R0482:Mki67	UTSW	7	135,301,158 (GRCm39)	missense	possibly damaging	0.60
R0508:Mki67	UTSW	7	135,302,075 (GRCm39)	missense	probably benign
R0532:Mki67	UTSW	7	135,299,893 (GRCm39)	nonsense	probably null
R0548:Mki67	UTSW	7	135,298,637 (GRCm39)	missense	possibly damaging	0.82
R0548:Mki67	UTSW	7	135,296,985 (GRCm39)	missense	probably damaging	1.00
R0557:Mki67	UTSW	7	135,300,990 (GRCm39)	missense	possibly damaging	0.48
R0627:Mki67	UTSW	7	135,309,987 (GRCm39)	missense	probably benign	0.31
R0631:Mki67	UTSW	7	135,306,117 (GRCm39)	missense	probably damaging	0.98
R0848:Mki67	UTSW	7	135,302,772 (GRCm39)	missense	probably benign	0.21
R1075:Mki67	UTSW	7	135,299,040 (GRCm39)	missense	probably benign	0.03
R1105:Mki67	UTSW	7	135,302,779 (GRCm39)	missense	probably benign	0.09
R1272:Mki67	UTSW	7	135,302,143 (GRCm39)	nonsense	probably null
R1331:Mki67	UTSW	7	135,300,005 (GRCm39)	missense	possibly damaging	0.71
R1486:Mki67	UTSW	7	135,301,449 (GRCm39)	missense	probably benign	0.00
R1510:Mki67	UTSW	7	135,297,900 (GRCm39)	missense	probably benign	0.26
R1573:Mki67	UTSW	7	135,296,845 (GRCm39)	missense	possibly damaging	0.93
R1586:Mki67	UTSW	7	135,315,701 (GRCm39)	nonsense	probably null
R1599:Mki67	UTSW	7	135,301,663 (GRCm39)	missense	probably benign	0.34
R1623:Mki67	UTSW	7	135,310,547 (GRCm39)	splice site	probably null
R1706:Mki67	UTSW	7	135,302,295 (GRCm39)	missense	probably benign	0.37
R1718:Mki67	UTSW	7	135,297,223 (GRCm39)	missense	probably damaging	1.00
R1785:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R1816:Mki67	UTSW	7	135,309,116 (GRCm39)	missense	possibly damaging	0.68
R1862:Mki67	UTSW	7	135,301,090 (GRCm39)	missense	probably benign	0.09
R1929:Mki67	UTSW	7	135,299,794 (GRCm39)	missense	possibly damaging	0.46
R1957:Mki67	UTSW	7	135,300,128 (GRCm39)	missense	probably benign	0.01
R1971:Mki67	UTSW	7	135,315,688 (GRCm39)	critical splice donor site	probably null
R1998:Mki67	UTSW	7	135,307,499 (GRCm39)	missense	probably benign	0.00
R2004:Mki67	UTSW	7	135,300,238 (GRCm39)	nonsense	probably null
R2005:Mki67	UTSW	7	135,300,238 (GRCm39)	nonsense	probably null
R2006:Mki67	UTSW	7	135,300,238 (GRCm39)	nonsense	probably null
R2109:Mki67	UTSW	7	135,299,592 (GRCm39)	missense	probably damaging	1.00
R2130:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R2131:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R2133:Mki67	UTSW	7	135,305,970 (GRCm39)	critical splice acceptor site	probably null
R2140:Mki67	UTSW	7	135,297,321 (GRCm39)	missense	possibly damaging	0.94
R2141:Mki67	UTSW	7	135,297,321 (GRCm39)	missense	possibly damaging	0.94
R2142:Mki67	UTSW	7	135,297,321 (GRCm39)	missense	possibly damaging	0.94
R2284:Mki67	UTSW	7	135,301,674 (GRCm39)	missense	probably damaging	0.99
R2869:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2869:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2871:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2871:Mki67	UTSW	7	135,309,878 (GRCm39)	missense	probably benign	0.19
R2913:Mki67	UTSW	7	135,302,415 (GRCm39)	missense	possibly damaging	0.71
R3404:Mki67	UTSW	7	135,309,204 (GRCm39)	missense	probably benign	0.01
R3405:Mki67	UTSW	7	135,309,204 (GRCm39)	missense	probably benign	0.01
R3406:Mki67	UTSW	7	135,309,204 (GRCm39)	missense	probably benign	0.01
R3777:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3778:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3787:Mki67	UTSW	7	135,302,012 (GRCm39)	missense	possibly damaging	0.93
R3847:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3848:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3853:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3971:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R3972:Mki67	UTSW	7	135,297,859 (GRCm39)	missense	probably benign	0.10
R4258:Mki67	UTSW	7	135,297,017 (GRCm39)	missense	possibly damaging	0.86
R4343:Mki67	UTSW	7	135,296,847 (GRCm39)	missense	probably benign	0.10
R4488:Mki67	UTSW	7	135,299,400 (GRCm39)	missense	probably benign	0.01
R4528:Mki67	UTSW	7	135,297,088 (GRCm39)	missense	probably damaging	1.00
R4713:Mki67	UTSW	7	135,297,198 (GRCm39)	missense	probably benign	0.35
R4867:Mki67	UTSW	7	135,301,585 (GRCm39)	missense	probably damaging	0.97
R4874:Mki67	UTSW	7	135,310,500 (GRCm39)	missense	probably damaging	0.97
R4897:Mki67	UTSW	7	135,298,474 (GRCm39)	missense	probably damaging	1.00
R5045:Mki67	UTSW	7	135,309,633 (GRCm39)	missense	possibly damaging	0.84
R5306:Mki67	UTSW	7	135,315,730 (GRCm39)	missense	probably damaging	1.00
R5309:Mki67	UTSW	7	135,302,559 (GRCm39)	missense	probably damaging	1.00
R5312:Mki67	UTSW	7	135,302,559 (GRCm39)	missense	probably damaging	1.00
R5379:Mki67	UTSW	7	135,299,190 (GRCm39)	missense	possibly damaging	0.95
R5506:Mki67	UTSW	7	135,301,710 (GRCm39)	missense	possibly damaging	0.60
R5513:Mki67	UTSW	7	135,309,479 (GRCm39)	missense	probably damaging	0.98
R5742:Mki67	UTSW	7	135,306,102 (GRCm39)	missense	probably benign	0.20
R5806:Mki67	UTSW	7	135,306,334 (GRCm39)	missense	probably damaging	1.00
R6008:Mki67	UTSW	7	135,299,158 (GRCm39)	missense	probably damaging	1.00
R6037:Mki67	UTSW	7	135,298,532 (GRCm39)	missense	possibly damaging	0.69
R6037:Mki67	UTSW	7	135,298,532 (GRCm39)	missense	possibly damaging	0.69
R6221:Mki67	UTSW	7	135,299,643 (GRCm39)	missense	probably benign	0.18
R6294:Mki67	UTSW	7	135,306,319 (GRCm39)	missense	probably benign	0.09
R6377:Mki67	UTSW	7	135,298,050 (GRCm39)	missense	possibly damaging	0.67
R6456:Mki67	UTSW	7	135,301,204 (GRCm39)	missense	possibly damaging	0.59
R6608:Mki67	UTSW	7	135,300,090 (GRCm39)	missense	probably benign	0.01
R6609:Mki67	UTSW	7	135,301,558 (GRCm39)	missense	possibly damaging	0.94
R6648:Mki67	UTSW	7	135,299,169 (GRCm39)	missense	probably damaging	1.00
R6901:Mki67	UTSW	7	135,310,489 (GRCm39)	splice site	probably null
R6978:Mki67	UTSW	7	135,303,691 (GRCm39)	missense	probably benign	0.10
R6985:Mki67	UTSW	7	135,315,594 (GRCm39)	missense	probably damaging	1.00
R7076:Mki67	UTSW	7	135,307,358 (GRCm39)	missense	probably damaging	0.98
R7217:Mki67	UTSW	7	135,305,911 (GRCm39)	missense	probably damaging	1.00
R7239:Mki67	UTSW	7	135,301,905 (GRCm39)	missense	possibly damaging	0.91
R7250:Mki67	UTSW	7	135,301,053 (GRCm39)	missense	possibly damaging	0.90
R7313:Mki67	UTSW	7	135,296,400 (GRCm39)	missense	probably benign	0.29
R7336:Mki67	UTSW	7	135,315,568 (GRCm39)	missense	probably benign	0.03
R7422:Mki67	UTSW	7	135,300,099 (GRCm39)	missense	probably damaging	1.00
R7451:Mki67	UTSW	7	135,301,080 (GRCm39)	missense	probably benign	0.01
R7502:Mki67	UTSW	7	135,302,512 (GRCm39)	missense	possibly damaging	0.53
R7513:Mki67	UTSW	7	135,294,952 (GRCm39)	missense	probably benign
R7578:Mki67	UTSW	7	135,302,644 (GRCm39)	missense	possibly damaging	0.68
R7619:Mki67	UTSW	7	135,301,106 (GRCm39)	missense	probably benign	0.01
R7646:Mki67	UTSW	7	135,298,498 (GRCm39)	missense	possibly damaging	0.63
R7659:Mki67	UTSW	7	135,299,155 (GRCm39)	missense	probably damaging	1.00
R7691:Mki67	UTSW	7	135,303,721 (GRCm39)	missense	not run
R7780:Mki67	UTSW	7	135,315,697 (GRCm39)	missense	probably benign	0.02
R7796:Mki67	UTSW	7	135,299,923 (GRCm39)	missense	probably damaging	1.00
R7904:Mki67	UTSW	7	135,294,816 (GRCm39)	missense	possibly damaging	0.90
R7911:Mki67	UTSW	7	135,306,333 (GRCm39)	missense	probably damaging	1.00
R7921:Mki67	UTSW	7	135,296,933 (GRCm39)	missense	probably benign	0.01
R7926:Mki67	UTSW	7	135,298,869 (GRCm39)	missense	possibly damaging	0.91
R7950:Mki67	UTSW	7	135,301,453 (GRCm39)	nonsense	probably null
R8130:Mki67	UTSW	7	135,299,293 (GRCm39)	missense	probably damaging	1.00
R8145:Mki67	UTSW	7	135,296,065 (GRCm39)	missense	probably benign	0.07
R8196:Mki67	UTSW	7	135,297,237 (GRCm39)	missense	probably damaging	1.00
R8220:Mki67	UTSW	7	135,299,850 (GRCm39)	missense	probably benign	0.03
R8299:Mki67	UTSW	7	135,306,349 (GRCm39)	missense	probably damaging	1.00
R8334:Mki67	UTSW	7	135,298,245 (GRCm39)	missense	probably damaging	0.98
R8350:Mki67	UTSW	7	135,300,200 (GRCm39)	missense	possibly damaging	0.82
R8358:Mki67	UTSW	7	135,301,855 (GRCm39)	missense	possibly damaging	0.46
R8529:Mki67	UTSW	7	135,315,688 (GRCm39)	critical splice donor site	probably null
R8700:Mki67	UTSW	7	135,307,436 (GRCm39)	missense
R8737:Mki67	UTSW	7	135,315,504 (GRCm39)	missense	probably damaging	1.00
R8914:Mki67	UTSW	7	135,299,595 (GRCm39)	missense
R8930:Mki67	UTSW	7	135,300,628 (GRCm39)	missense	possibly damaging	0.92
R8932:Mki67	UTSW	7	135,300,628 (GRCm39)	missense	possibly damaging	0.92
R8972:Mki67	UTSW	7	135,297,364 (GRCm39)	missense	possibly damaging	0.54
R8973:Mki67	UTSW	7	135,297,364 (GRCm39)	missense	possibly damaging	0.54
R8975:Mki67	UTSW	7	135,300,129 (GRCm39)	missense	probably benign	0.01
R8975:Mki67	UTSW	7	135,297,364 (GRCm39)	missense	possibly damaging	0.54
R9071:Mki67	UTSW	7	135,301,205 (GRCm39)	missense	probably benign	0.00
R9241:Mki67	UTSW	7	135,297,653 (GRCm39)	missense	possibly damaging	0.93
R9387:Mki67	UTSW	7	135,302,378 (GRCm39)	missense	probably damaging	0.99
R9524:Mki67	UTSW	7	135,305,913 (GRCm39)	missense	probably damaging	1.00
R9565:Mki67	UTSW	7	135,309,233 (GRCm39)	frame shift	probably null
R9782:Mki67	UTSW	7	135,306,066 (GRCm39)	critical splice donor site	probably null
X0020:Mki67	UTSW	7	135,315,730 (GRCm39)	missense	probably damaging	0.96
X0065:Mki67	UTSW	7	135,315,573 (GRCm39)	missense	possibly damaging	0.95

Predicted Primers

PCR Primer
(F):5'- TTCATCAGTGTGGCCTAGGG -3'
(R):5'- GTTTAACTGGCAGGAGGAACC -3'

Sequencing Primer
(F):5'- GTTTGGATTGGTCCTTTGAGACCAG -3'
(R):5'- GAACTCACCAGTTTCCAAGAGG -3'

Posted On

2021-04-30