Incidental Mutation 'R8790:R3hdm2'
| ID |
670880 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
R3hdm2
|
| Ensembl Gene |
ENSMUSG00000025404 |
| Gene Name |
R3H domain containing 2 |
| Synonyms |
1300003K24Rik |
| MMRRC Submission |
068634-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.548)
|
| Stock # |
R8790 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
127216201-127335253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 127293521 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Alanine
at position 142
(S142A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000069724
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064793]
[ENSMUST00000077046]
[ENSMUST00000105249]
[ENSMUST00000105250]
[ENSMUST00000105251]
[ENSMUST00000164161]
[ENSMUST00000164831]
[ENSMUST00000165440]
[ENSMUST00000166820]
[ENSMUST00000168780]
[ENSMUST00000169888]
[ENSMUST00000170336]
|
| AlphaFold |
Q80TM6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000064793
AA Change: S142A
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000069724
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
low complexity region
|
306 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
398 |
429 |
N/A |
INTRINSIC |
|
low complexity region
|
442 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
699 |
730 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000077046
AA Change: S142A
PolyPhen 2
Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000076303
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
7.4e-14 |
PFAM |
|
low complexity region
|
338 |
350 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
474 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
744 |
775 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105249
AA Change: S142A
PolyPhen 2
Score 0.982 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000100884
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.4e-12 |
PFAM |
|
low complexity region
|
320 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
723 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105250
AA Change: S142A
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000100885
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.6e-12 |
PFAM |
|
low complexity region
|
320 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
481 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
757 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105251
AA Change: S142A
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000100886
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.6e-12 |
PFAM |
|
low complexity region
|
320 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
481 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
757 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164161
|
| SMART Domains |
Protein: ENSMUSP00000126185
Gene: ENSMUSG00000025404
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000164831
AA Change: S142A
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000131007
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
low complexity region
|
306 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
398 |
429 |
N/A |
INTRINSIC |
|
low complexity region
|
678 |
709 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165440
|
| SMART Domains |
Protein: ENSMUSP00000133118
Gene: ENSMUSG00000025404
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:SUZ
|
17 |
64 |
1.4e-13 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166820
AA Change: S142A
PolyPhen 2
Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000126608
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.7e-12 |
PFAM |
|
low complexity region
|
338 |
350 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
474 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
744 |
775 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168780
|
| SMART Domains |
Protein: ENSMUSP00000127872
Gene: ENSMUSG00000025404
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169888
|
| SMART Domains |
Protein: ENSMUSP00000126760
Gene: ENSMUSG00000025404
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:SUZ
|
7 |
54 |
4.7e-12 |
PFAM |
|
low complexity region
|
71 |
83 |
N/A |
INTRINSIC |
|
low complexity region
|
163 |
194 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
474 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000170336
AA Change: S142A
PolyPhen 2
Score 0.969 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000128659
Gene: ENSMUSG00000025404
AA Change: S142A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
low complexity region
|
306 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
398 |
429 |
N/A |
INTRINSIC |
|
low complexity region
|
442 |
467 |
N/A |
INTRINSIC |
|
low complexity region
|
712 |
743 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0767 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
100% (83/83) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610008E11Rik |
G |
A |
10: 78,928,285 (GRCm39) |
P68S |
possibly damaging |
Het |
| Abcb5 |
T |
A |
12: 118,831,620 (GRCm39) |
N1244I |
possibly damaging |
Het |
| Abcb9 |
A |
G |
5: 124,215,304 (GRCm39) |
I479T |
probably damaging |
Het |
| Abi3bp |
A |
T |
16: 56,495,437 (GRCm39) |
I920F |
probably damaging |
Het |
| Adcy6 |
T |
A |
15: 98,496,881 (GRCm39) |
T465S |
probably damaging |
Het |
| Ankrd12 |
A |
T |
17: 66,290,153 (GRCm39) |
I1760N |
possibly damaging |
Het |
| Aoah |
C |
T |
13: 21,035,840 (GRCm39) |
R140C |
probably benign |
Het |
| Bmp7 |
T |
A |
2: 172,712,060 (GRCm39) |
D388V |
probably benign |
Het |
| Bphl |
C |
T |
13: 34,244,468 (GRCm39) |
A195V |
probably benign |
Het |
| Cckar |
A |
G |
5: 53,857,291 (GRCm39) |
V373A |
probably damaging |
Het |
| Cd79b |
T |
G |
11: 106,202,873 (GRCm39) |
D243A |
possibly damaging |
Het |
| Cdc25a |
T |
A |
9: 109,716,416 (GRCm39) |
|
probably null |
Het |
| Cfap57 |
T |
A |
4: 118,439,111 (GRCm39) |
Q805L |
possibly damaging |
Het |
| Ckap2l |
A |
T |
2: 129,111,172 (GRCm39) |
M675K |
possibly damaging |
Het |
| Cluap1 |
T |
A |
16: 3,735,787 (GRCm39) |
|
probably benign |
Het |
| Cyp2b9 |
A |
G |
7: 25,898,167 (GRCm39) |
|
probably benign |
Het |
| D930020B18Rik |
G |
A |
10: 121,503,568 (GRCm39) |
G248S |
possibly damaging |
Het |
| Ddx1 |
A |
T |
12: 13,273,993 (GRCm39) |
I570N |
probably damaging |
Het |
| Dmkn |
G |
A |
7: 30,463,449 (GRCm39) |
S34N |
probably benign |
Het |
| Dnaaf2 |
T |
C |
12: 69,244,068 (GRCm39) |
D331G |
probably damaging |
Het |
| Dnah1 |
A |
T |
14: 31,018,232 (GRCm39) |
Y1429N |
possibly damaging |
Het |
| Dnajc5b |
T |
A |
3: 19,600,981 (GRCm39) |
L26Q |
probably damaging |
Het |
| Epb41l1 |
T |
G |
2: 156,345,722 (GRCm39) |
F242V |
possibly damaging |
Het |
| Esam |
A |
T |
9: 37,442,927 (GRCm39) |
I72F |
probably benign |
Het |
| Fam110a |
C |
T |
2: 151,812,338 (GRCm39) |
R144H |
probably damaging |
Het |
| Fam186a |
T |
C |
15: 99,841,024 (GRCm39) |
D1740G |
possibly damaging |
Het |
| Fam98a |
A |
G |
17: 75,854,684 (GRCm39) |
F42L |
possibly damaging |
Het |
| Fras1 |
C |
T |
5: 96,903,236 (GRCm39) |
P3038S |
probably damaging |
Het |
| Gm32742 |
C |
A |
9: 51,059,140 (GRCm39) |
G1035C |
probably damaging |
Het |
| Irf5 |
T |
A |
6: 29,535,026 (GRCm39) |
|
probably benign |
Het |
| Jam2 |
T |
A |
16: 84,606,259 (GRCm39) |
I91K |
possibly damaging |
Het |
| Klhdc3 |
A |
G |
17: 46,991,626 (GRCm39) |
|
probably benign |
Het |
| Lgi1 |
C |
T |
19: 38,289,296 (GRCm39) |
S215F |
possibly damaging |
Het |
| Lrp1 |
G |
A |
10: 127,374,946 (GRCm39) |
T4504I |
probably damaging |
Het |
| Mafa |
T |
A |
15: 75,619,224 (GRCm39) |
H183L |
probably benign |
Het |
| Map2 |
T |
C |
1: 66,477,997 (GRCm39) |
V1773A |
probably damaging |
Het |
| Mesp1 |
G |
A |
7: 79,442,825 (GRCm39) |
R151* |
probably null |
Het |
| Mphosph9 |
T |
C |
5: 124,453,736 (GRCm39) |
D192G |
probably damaging |
Het |
| Mthfr |
C |
A |
4: 148,139,991 (GRCm39) |
D678E |
probably benign |
Het |
| Myo15a |
A |
C |
11: 60,367,362 (GRCm39) |
T41P |
possibly damaging |
Het |
| Myo15a |
G |
T |
11: 60,378,047 (GRCm39) |
R185L |
|
Het |
| Myom2 |
T |
G |
8: 15,169,242 (GRCm39) |
L1136W |
probably damaging |
Het |
| Naa30 |
A |
G |
14: 49,418,208 (GRCm39) |
D316G |
probably benign |
Het |
| Ngef |
T |
C |
1: 87,405,319 (GRCm39) |
Q697R |
probably benign |
Het |
| Nin |
T |
C |
12: 70,067,793 (GRCm39) |
R1945G |
|
Het |
| Obox8 |
A |
T |
7: 14,066,908 (GRCm39) |
Y45* |
probably null |
Het |
| Ocln |
C |
T |
13: 100,642,727 (GRCm39) |
V452I |
probably benign |
Het |
| Oog3 |
T |
A |
4: 143,885,710 (GRCm39) |
D296V |
possibly damaging |
Het |
| Or5a1 |
T |
C |
19: 12,097,906 (GRCm39) |
N57D |
probably damaging |
Het |
| Or5h19 |
T |
C |
16: 58,856,580 (GRCm39) |
I173M |
possibly damaging |
Het |
| Or8g4 |
T |
A |
9: 39,662,204 (GRCm39) |
I174K |
probably damaging |
Het |
| Or8k35 |
T |
C |
2: 86,424,278 (GRCm39) |
K298R |
possibly damaging |
Het |
| Papln |
T |
C |
12: 83,823,918 (GRCm39) |
V499A |
probably benign |
Het |
| Paxip1 |
G |
T |
5: 27,977,078 (GRCm39) |
P328Q |
unknown |
Het |
| Pcnx2 |
T |
C |
8: 126,604,306 (GRCm39) |
H650R |
probably benign |
Het |
| Pcnx3 |
A |
T |
19: 5,735,206 (GRCm39) |
V540E |
possibly damaging |
Het |
| Pnpla5 |
C |
T |
15: 84,002,819 (GRCm39) |
G255R |
probably damaging |
Het |
| Ppdpf |
G |
T |
2: 180,829,646 (GRCm39) |
E34* |
probably null |
Het |
| Pum3 |
T |
C |
19: 27,394,199 (GRCm39) |
Y357C |
probably damaging |
Het |
| Rasa3 |
A |
T |
8: 13,727,391 (GRCm39) |
|
probably null |
Het |
| Rcor2 |
T |
A |
19: 7,246,340 (GRCm39) |
M5K |
possibly damaging |
Het |
| Rere |
A |
G |
4: 150,593,332 (GRCm39) |
T309A |
unknown |
Het |
| Ryr1 |
A |
T |
7: 28,776,297 (GRCm39) |
I2250N |
probably damaging |
Het |
| Sema6c |
T |
C |
3: 95,075,341 (GRCm39) |
V130A |
probably benign |
Het |
| Slc26a9 |
T |
A |
1: 131,683,155 (GRCm39) |
S200T |
probably damaging |
Het |
| Slc38a10 |
A |
G |
11: 120,023,519 (GRCm39) |
L299P |
possibly damaging |
Het |
| Smim10l1 |
G |
T |
6: 133,084,848 (GRCm39) |
V72L |
unknown |
Het |
| Sptbn2 |
C |
A |
19: 4,782,052 (GRCm39) |
F430L |
probably damaging |
Het |
| Svep1 |
T |
A |
4: 58,118,145 (GRCm39) |
Y859F |
possibly damaging |
Het |
| Svil |
C |
A |
18: 5,056,098 (GRCm39) |
Q324K |
possibly damaging |
Het |
| Tgfb1i1 |
A |
T |
7: 127,852,049 (GRCm39) |
D377V |
probably damaging |
Het |
| Tmed10 |
C |
A |
12: 85,390,254 (GRCm39) |
W203L |
probably damaging |
Het |
| Tmem51 |
T |
A |
4: 141,765,056 (GRCm39) |
M1L |
possibly damaging |
Het |
| Tmprss11e |
A |
G |
5: 86,855,259 (GRCm39) |
V382A |
probably benign |
Het |
| Tnfrsf13b |
G |
T |
11: 61,038,350 (GRCm39) |
R211L |
possibly damaging |
Het |
| Tns3 |
A |
G |
11: 8,468,273 (GRCm39) |
V317A |
probably damaging |
Het |
| Top3a |
G |
A |
11: 60,631,363 (GRCm39) |
P1000S |
possibly damaging |
Het |
| Traj32 |
A |
T |
14: 54,423,587 (GRCm39) |
I10F |
|
Het |
| Trav8-1 |
T |
A |
14: 53,707,677 (GRCm39) |
C106S |
probably damaging |
Het |
| Trbv2 |
A |
G |
6: 41,024,655 (GRCm39) |
I24V |
probably benign |
Het |
| Ubap2 |
A |
G |
4: 41,209,351 (GRCm39) |
|
probably null |
Het |
| Vmn2r97 |
T |
A |
17: 19,160,472 (GRCm39) |
C536S |
probably damaging |
Het |
| Zfp879 |
G |
T |
11: 50,723,429 (GRCm39) |
C542* |
probably null |
Het |
| Znfx1 |
C |
T |
2: 166,892,500 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in R3hdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01397:R3hdm2
|
APN |
10 |
127,294,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02114:R3hdm2
|
APN |
10 |
127,319,978 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02116:R3hdm2
|
APN |
10 |
127,334,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02549:R3hdm2
|
APN |
10 |
127,320,094 (GRCm39) |
splice site |
probably benign |
|
|
IGL02647:R3hdm2
|
APN |
10 |
127,295,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02696:R3hdm2
|
APN |
10 |
127,300,888 (GRCm39) |
splice site |
probably null |
|
|
IGL02732:R3hdm2
|
APN |
10 |
127,319,929 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0131:R3hdm2
|
UTSW |
10 |
127,334,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:R3hdm2
|
UTSW |
10 |
127,334,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0132:R3hdm2
|
UTSW |
10 |
127,334,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0157:R3hdm2
|
UTSW |
10 |
127,307,858 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0179:R3hdm2
|
UTSW |
10 |
127,330,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0196:R3hdm2
|
UTSW |
10 |
127,320,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0401:R3hdm2
|
UTSW |
10 |
127,294,042 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0505:R3hdm2
|
UTSW |
10 |
127,293,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:R3hdm2
|
UTSW |
10 |
127,280,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1188:R3hdm2
|
UTSW |
10 |
127,288,624 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1466:R3hdm2
|
UTSW |
10 |
127,312,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1466:R3hdm2
|
UTSW |
10 |
127,312,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1503:R3hdm2
|
UTSW |
10 |
127,307,695 (GRCm39) |
nonsense |
probably null |
|
|
R1584:R3hdm2
|
UTSW |
10 |
127,312,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1652:R3hdm2
|
UTSW |
10 |
127,330,960 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1901:R3hdm2
|
UTSW |
10 |
127,334,337 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3735:R3hdm2
|
UTSW |
10 |
127,300,879 (GRCm39) |
missense |
probably benign |
|
|
R5261:R3hdm2
|
UTSW |
10 |
127,334,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5329:R3hdm2
|
UTSW |
10 |
127,294,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5379:R3hdm2
|
UTSW |
10 |
127,307,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5380:R3hdm2
|
UTSW |
10 |
127,321,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5387:R3hdm2
|
UTSW |
10 |
127,321,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5558:R3hdm2
|
UTSW |
10 |
127,280,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5773:R3hdm2
|
UTSW |
10 |
127,280,172 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5936:R3hdm2
|
UTSW |
10 |
127,307,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:R3hdm2
|
UTSW |
10 |
127,295,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6160:R3hdm2
|
UTSW |
10 |
127,320,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6191:R3hdm2
|
UTSW |
10 |
127,320,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7058:R3hdm2
|
UTSW |
10 |
127,320,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7224:R3hdm2
|
UTSW |
10 |
127,294,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7253:R3hdm2
|
UTSW |
10 |
127,317,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7305:R3hdm2
|
UTSW |
10 |
127,312,547 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7349:R3hdm2
|
UTSW |
10 |
127,328,515 (GRCm39) |
missense |
probably benign |
|
|
R7431:R3hdm2
|
UTSW |
10 |
127,294,016 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7891:R3hdm2
|
UTSW |
10 |
127,334,443 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8477:R3hdm2
|
UTSW |
10 |
127,320,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8503:R3hdm2
|
UTSW |
10 |
127,328,481 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8782:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8783:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8784:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8787:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8789:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9041:R3hdm2
|
UTSW |
10 |
127,320,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9198:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9200:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9202:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9706:R3hdm2
|
UTSW |
10 |
127,334,298 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9760:R3hdm2
|
UTSW |
10 |
127,280,182 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCTCACAGAGCTGACAGTAAATG -3'
(R):5'- TTGTCAACTCGTCAAAACACAG -3'
Sequencing Primer
(F):5'- AATGCCATTCAGGGTTTCATGC -3'
(R):5'- GTCAAAACACAGAAATCTCAATGTG -3'
|
| Posted On |
2021-04-30 |
Incidental Mutation