Mutagenetix > Incidental Mutation

Incidental Mutation 'R8790:Dnah1'

670899

Institutional Source

Beutler Lab

Gene Symbol

Dnah1

Ensembl Gene

ENSMUSG00000019027

Gene Name

dynein, axonemal, heavy chain 1

Synonyms

MDHC7, B230373P09Rik, ferf1, G1-415-19, E030034C22Rik, Dnahc1

MMRRC Submission

068634-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8790 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

30982332-31045853 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 31018232 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Asparagine at position 1429 (Y1429N)

Ref Sequence

ENSEMBL: ENSMUSP00000043281 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048603]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000048603
AA Change: Y1429N

PolyPhen 2 Score 0.890 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000043281
Gene: ENSMUSG00000019027
AA Change: Y1429N

Domain	Start	End	E-Value	Type
low complexity region	43	59	N/A	INTRINSIC
Pfam:DHC_N2	998	1404	6.3e-146	PFAM
AAA	1558	1697	6.02e-1	SMART
AAA	1839	2077	4.66e0	SMART
low complexity region	2149	2157	N/A	INTRINSIC
AAA	2204	2353	2.35e-1	SMART
Pfam:AAA_8	2533	2803	7.7e-84	PFAM
Pfam:MT	2815	3165	9.9e-57	PFAM
Pfam:AAA_9	3185	3410	1.1e-93	PFAM
Pfam:Dynein_heavy	3545	4246	2.7e-275	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

100% (83/83)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]
PHENOTYPE: Homozygous mutants are male sterile, and show impaired ciliary and flagellar motility that is also observed in the tracheal cilia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 84 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610008E11Rik	G	A	10: 78,928,285 (GRCm39)	P68S	possibly damaging	Het
Abcb5	T	A	12: 118,831,620 (GRCm39)	N1244I	possibly damaging	Het
Abcb9	A	G	5: 124,215,304 (GRCm39)	I479T	probably damaging	Het
Abi3bp	A	T	16: 56,495,437 (GRCm39)	I920F	probably damaging	Het
Adcy6	T	A	15: 98,496,881 (GRCm39)	T465S	probably damaging	Het
Ankrd12	A	T	17: 66,290,153 (GRCm39)	I1760N	possibly damaging	Het
Aoah	C	T	13: 21,035,840 (GRCm39)	R140C	probably benign	Het
Bmp7	T	A	2: 172,712,060 (GRCm39)	D388V	probably benign	Het
Bphl	C	T	13: 34,244,468 (GRCm39)	A195V	probably benign	Het
Cckar	A	G	5: 53,857,291 (GRCm39)	V373A	probably damaging	Het
Cd79b	T	G	11: 106,202,873 (GRCm39)	D243A	possibly damaging	Het
Cdc25a	T	A	9: 109,716,416 (GRCm39)		probably null	Het
Cfap57	T	A	4: 118,439,111 (GRCm39)	Q805L	possibly damaging	Het
Ckap2l	A	T	2: 129,111,172 (GRCm39)	M675K	possibly damaging	Het
Cluap1	T	A	16: 3,735,787 (GRCm39)		probably benign	Het
Cyp2b9	A	G	7: 25,898,167 (GRCm39)		probably benign	Het
D930020B18Rik	G	A	10: 121,503,568 (GRCm39)	G248S	possibly damaging	Het
Ddx1	A	T	12: 13,273,993 (GRCm39)	I570N	probably damaging	Het
Dmkn	G	A	7: 30,463,449 (GRCm39)	S34N	probably benign	Het
Dnaaf2	T	C	12: 69,244,068 (GRCm39)	D331G	probably damaging	Het
Dnajc5b	T	A	3: 19,600,981 (GRCm39)	L26Q	probably damaging	Het
Epb41l1	T	G	2: 156,345,722 (GRCm39)	F242V	possibly damaging	Het
Esam	A	T	9: 37,442,927 (GRCm39)	I72F	probably benign	Het
Fam110a	C	T	2: 151,812,338 (GRCm39)	R144H	probably damaging	Het
Fam186a	T	C	15: 99,841,024 (GRCm39)	D1740G	possibly damaging	Het
Fam98a	A	G	17: 75,854,684 (GRCm39)	F42L	possibly damaging	Het
Fras1	C	T	5: 96,903,236 (GRCm39)	P3038S	probably damaging	Het
Gm32742	C	A	9: 51,059,140 (GRCm39)	G1035C	probably damaging	Het
Irf5	T	A	6: 29,535,026 (GRCm39)		probably benign	Het
Jam2	T	A	16: 84,606,259 (GRCm39)	I91K	possibly damaging	Het
Klhdc3	A	G	17: 46,991,626 (GRCm39)		probably benign	Het
Lgi1	C	T	19: 38,289,296 (GRCm39)	S215F	possibly damaging	Het
Lrp1	G	A	10: 127,374,946 (GRCm39)	T4504I	probably damaging	Het
Mafa	T	A	15: 75,619,224 (GRCm39)	H183L	probably benign	Het
Map2	T	C	1: 66,477,997 (GRCm39)	V1773A	probably damaging	Het
Mesp1	G	A	7: 79,442,825 (GRCm39)	R151*	probably null	Het
Mphosph9	T	C	5: 124,453,736 (GRCm39)	D192G	probably damaging	Het
Mthfr	C	A	4: 148,139,991 (GRCm39)	D678E	probably benign	Het
Myo15a	A	C	11: 60,367,362 (GRCm39)	T41P	possibly damaging	Het
Myo15a	G	T	11: 60,378,047 (GRCm39)	R185L		Het
Myom2	T	G	8: 15,169,242 (GRCm39)	L1136W	probably damaging	Het
Naa30	A	G	14: 49,418,208 (GRCm39)	D316G	probably benign	Het
Ngef	T	C	1: 87,405,319 (GRCm39)	Q697R	probably benign	Het
Nin	T	C	12: 70,067,793 (GRCm39)	R1945G		Het
Obox8	A	T	7: 14,066,908 (GRCm39)	Y45*	probably null	Het
Ocln	C	T	13: 100,642,727 (GRCm39)	V452I	probably benign	Het
Oog3	T	A	4: 143,885,710 (GRCm39)	D296V	possibly damaging	Het
Or5a1	T	C	19: 12,097,906 (GRCm39)	N57D	probably damaging	Het
Or5h19	T	C	16: 58,856,580 (GRCm39)	I173M	possibly damaging	Het
Or8g4	T	A	9: 39,662,204 (GRCm39)	I174K	probably damaging	Het
Or8k35	T	C	2: 86,424,278 (GRCm39)	K298R	possibly damaging	Het
Papln	T	C	12: 83,823,918 (GRCm39)	V499A	probably benign	Het
Paxip1	G	T	5: 27,977,078 (GRCm39)	P328Q	unknown	Het
Pcnx2	T	C	8: 126,604,306 (GRCm39)	H650R	probably benign	Het
Pcnx3	A	T	19: 5,735,206 (GRCm39)	V540E	possibly damaging	Het
Pnpla5	C	T	15: 84,002,819 (GRCm39)	G255R	probably damaging	Het
Ppdpf	G	T	2: 180,829,646 (GRCm39)	E34*	probably null	Het
Pum3	T	C	19: 27,394,199 (GRCm39)	Y357C	probably damaging	Het
R3hdm2	T	G	10: 127,293,521 (GRCm39)	S142A	probably damaging	Het
Rasa3	A	T	8: 13,727,391 (GRCm39)		probably null	Het
Rcor2	T	A	19: 7,246,340 (GRCm39)	M5K	possibly damaging	Het
Rere	A	G	4: 150,593,332 (GRCm39)	T309A	unknown	Het
Ryr1	A	T	7: 28,776,297 (GRCm39)	I2250N	probably damaging	Het
Sema6c	T	C	3: 95,075,341 (GRCm39)	V130A	probably benign	Het
Slc26a9	T	A	1: 131,683,155 (GRCm39)	S200T	probably damaging	Het
Slc38a10	A	G	11: 120,023,519 (GRCm39)	L299P	possibly damaging	Het
Smim10l1	G	T	6: 133,084,848 (GRCm39)	V72L	unknown	Het
Sptbn2	C	A	19: 4,782,052 (GRCm39)	F430L	probably damaging	Het
Svep1	T	A	4: 58,118,145 (GRCm39)	Y859F	possibly damaging	Het
Svil	C	A	18: 5,056,098 (GRCm39)	Q324K	possibly damaging	Het
Tgfb1i1	A	T	7: 127,852,049 (GRCm39)	D377V	probably damaging	Het
Tmed10	C	A	12: 85,390,254 (GRCm39)	W203L	probably damaging	Het
Tmem51	T	A	4: 141,765,056 (GRCm39)	M1L	possibly damaging	Het
Tmprss11e	A	G	5: 86,855,259 (GRCm39)	V382A	probably benign	Het
Tnfrsf13b	G	T	11: 61,038,350 (GRCm39)	R211L	possibly damaging	Het
Tns3	A	G	11: 8,468,273 (GRCm39)	V317A	probably damaging	Het
Top3a	G	A	11: 60,631,363 (GRCm39)	P1000S	possibly damaging	Het
Traj32	A	T	14: 54,423,587 (GRCm39)	I10F		Het
Trav8-1	T	A	14: 53,707,677 (GRCm39)	C106S	probably damaging	Het
Trbv2	A	G	6: 41,024,655 (GRCm39)	I24V	probably benign	Het
Ubap2	A	G	4: 41,209,351 (GRCm39)		probably null	Het
Vmn2r97	T	A	17: 19,160,472 (GRCm39)	C536S	probably damaging	Het
Zfp879	G	T	11: 50,723,429 (GRCm39)	C542*	probably null	Het
Znfx1	C	T	2: 166,892,500 (GRCm39)		probably benign	Het

Other mutations in Dnah1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Dnah1	APN	14	31,009,830 (GRCm39)	missense	probably benign	0.01
IGL00227:Dnah1	APN	14	31,008,853 (GRCm39)	missense	probably damaging	1.00
IGL00491:Dnah1	APN	14	30,983,796 (GRCm39)	missense	probably damaging	1.00
IGL00787:Dnah1	APN	14	31,022,020 (GRCm39)	missense	possibly damaging	0.91
IGL00809:Dnah1	APN	14	31,022,766 (GRCm39)	nonsense	probably null
IGL00911:Dnah1	APN	14	31,026,391 (GRCm39)	splice site	probably null
IGL00949:Dnah1	APN	14	31,029,047 (GRCm39)	missense	probably benign	0.00
IGL00976:Dnah1	APN	14	31,000,095 (GRCm39)	missense	probably damaging	1.00
IGL01484:Dnah1	APN	14	31,021,897 (GRCm39)	missense	probably damaging	0.98
IGL01629:Dnah1	APN	14	31,014,277 (GRCm39)	missense	probably damaging	1.00
IGL01716:Dnah1	APN	14	30,985,335 (GRCm39)	missense	probably benign	0.34
IGL01893:Dnah1	APN	14	30,988,427 (GRCm39)	missense	probably damaging	1.00
IGL01933:Dnah1	APN	14	31,032,872 (GRCm39)	missense	probably benign	0.40
IGL01938:Dnah1	APN	14	31,005,844 (GRCm39)	missense	probably benign
IGL02032:Dnah1	APN	14	30,996,326 (GRCm39)	missense	probably benign
IGL02052:Dnah1	APN	14	30,990,743 (GRCm39)	missense	probably damaging	0.99
IGL02097:Dnah1	APN	14	31,026,958 (GRCm39)	missense	possibly damaging	0.92
IGL02127:Dnah1	APN	14	31,026,885 (GRCm39)	missense	probably benign	0.00
IGL02143:Dnah1	APN	14	31,005,246 (GRCm39)	missense	probably damaging	1.00
IGL02158:Dnah1	APN	14	31,022,924 (GRCm39)	missense	probably benign	0.00
IGL02442:Dnah1	APN	14	31,009,835 (GRCm39)	missense	probably damaging	1.00
IGL02525:Dnah1	APN	14	31,027,790 (GRCm39)	missense	probably benign	0.05
IGL02558:Dnah1	APN	14	30,996,336 (GRCm39)	missense	possibly damaging	0.96
IGL02633:Dnah1	APN	14	31,006,772 (GRCm39)	missense	probably benign	0.05
IGL02720:Dnah1	APN	14	30,984,177 (GRCm39)	missense	probably damaging	0.96
IGL02728:Dnah1	APN	14	31,005,955 (GRCm39)	missense	probably benign	0.44
IGL02738:Dnah1	APN	14	31,014,597 (GRCm39)	missense	probably benign	0.27
IGL02863:Dnah1	APN	14	31,017,250 (GRCm39)	missense	probably damaging	0.99
IGL02944:Dnah1	APN	14	31,022,828 (GRCm39)	missense	possibly damaging	0.88
IGL03110:Dnah1	APN	14	30,988,674 (GRCm39)	missense	probably benign	0.40
IGL03201:Dnah1	APN	14	31,022,906 (GRCm39)	missense	probably benign	0.13
IGL03215:Dnah1	APN	14	30,996,348 (GRCm39)	missense	probably damaging	1.00
IGL03230:Dnah1	APN	14	30,992,023 (GRCm39)	missense	probably damaging	1.00
IGL03248:Dnah1	APN	14	30,991,846 (GRCm39)	missense	probably damaging	1.00
IGL03267:Dnah1	APN	14	31,008,545 (GRCm39)	missense	probably benign	0.00
IGL03299:Dnah1	APN	14	31,037,079 (GRCm39)	nonsense	probably null
IGL03301:Dnah1	APN	14	31,014,649 (GRCm39)	missense	probably damaging	1.00
ergonomic	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
Faraday	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
K3955:Dnah1	UTSW	14	30,988,416 (GRCm39)	missense	probably benign
PIT1430001:Dnah1	UTSW	14	30,984,537 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Dnah1	UTSW	14	31,006,412 (GRCm39)	missense	probably damaging	1.00
R0043:Dnah1	UTSW	14	30,996,362 (GRCm39)	missense	probably damaging	0.97
R0092:Dnah1	UTSW	14	30,993,566 (GRCm39)	missense	probably benign	0.00
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0101:Dnah1	UTSW	14	31,005,856 (GRCm39)	missense	probably damaging	1.00
R0119:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0136:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0144:Dnah1	UTSW	14	30,989,831 (GRCm39)	splice site	probably benign
R0279:Dnah1	UTSW	14	31,024,332 (GRCm39)	missense	possibly damaging	0.94
R0299:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah1	UTSW	14	31,000,108 (GRCm39)	missense	probably benign	0.00
R0739:Dnah1	UTSW	14	30,987,872 (GRCm39)	nonsense	probably null
R0789:Dnah1	UTSW	14	31,026,548 (GRCm39)	missense	probably benign
R0826:Dnah1	UTSW	14	31,025,864 (GRCm39)	missense	probably benign	0.02
R1102:Dnah1	UTSW	14	31,018,414 (GRCm39)	nonsense	probably null
R1116:Dnah1	UTSW	14	31,029,824 (GRCm39)	missense	probably benign	0.13
R1229:Dnah1	UTSW	14	31,032,808 (GRCm39)	missense	probably benign	0.11
R1447:Dnah1	UTSW	14	31,028,855 (GRCm39)	missense	probably benign	0.06
R1449:Dnah1	UTSW	14	30,985,908 (GRCm39)	missense	probably damaging	1.00
R1462:Dnah1	UTSW	14	30,990,738 (GRCm39)	splice site	probably benign
R1482:Dnah1	UTSW	14	31,016,831 (GRCm39)	missense	probably damaging	1.00
R1500:Dnah1	UTSW	14	31,038,715 (GRCm39)	missense	probably benign
R1512:Dnah1	UTSW	14	31,014,994 (GRCm39)	missense	probably damaging	1.00
R1591:Dnah1	UTSW	14	30,994,289 (GRCm39)	missense	probably benign	0.01
R1598:Dnah1	UTSW	14	31,023,219 (GRCm39)	missense	probably benign	0.07
R1644:Dnah1	UTSW	14	31,024,249 (GRCm39)	splice site	probably benign
R1672:Dnah1	UTSW	14	30,998,157 (GRCm39)	missense	probably damaging	1.00
R1713:Dnah1	UTSW	14	31,001,139 (GRCm39)	missense	probably damaging	1.00
R1769:Dnah1	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
R1796:Dnah1	UTSW	14	30,983,050 (GRCm39)	missense	probably benign	0.00
R1902:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1903:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1905:Dnah1	UTSW	14	30,986,587 (GRCm39)	missense	probably benign	0.06
R1908:Dnah1	UTSW	14	30,984,515 (GRCm39)	missense	probably damaging	1.00
R1972:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R1973:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R2004:Dnah1	UTSW	14	31,023,813 (GRCm39)	missense	possibly damaging	0.79
R2051:Dnah1	UTSW	14	31,001,080 (GRCm39)	missense	probably damaging	1.00
R2062:Dnah1	UTSW	14	30,993,086 (GRCm39)	missense	probably damaging	1.00
R2188:Dnah1	UTSW	14	31,001,121 (GRCm39)	missense	probably damaging	0.98
R2240:Dnah1	UTSW	14	31,021,931 (GRCm39)	missense	probably benign	0.00
R2862:Dnah1	UTSW	14	31,006,719 (GRCm39)	missense	probably benign	0.21
R2894:Dnah1	UTSW	14	31,020,718 (GRCm39)	missense	possibly damaging	0.67
R3120:Dnah1	UTSW	14	30,988,779 (GRCm39)	nonsense	probably null
R3410:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3411:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3435:Dnah1	UTSW	14	31,038,631 (GRCm39)	missense	probably damaging	0.96
R3615:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3616:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3741:Dnah1	UTSW	14	30,987,424 (GRCm39)	splice site	probably benign
R3805:Dnah1	UTSW	14	31,016,720 (GRCm39)	missense	possibly damaging	0.67
R3894:Dnah1	UTSW	14	31,028,985 (GRCm39)	missense	probably benign
R4007:Dnah1	UTSW	14	31,025,741 (GRCm39)	splice site	probably benign
R4201:Dnah1	UTSW	14	30,984,227 (GRCm39)	missense	probably benign	0.00
R4232:Dnah1	UTSW	14	31,026,873 (GRCm39)	missense	probably benign
R4372:Dnah1	UTSW	14	31,026,879 (GRCm39)	missense	probably damaging	1.00
R4391:Dnah1	UTSW	14	31,016,792 (GRCm39)	missense	probably damaging	1.00
R4423:Dnah1	UTSW	14	31,006,718 (GRCm39)	missense	probably benign	0.00
R4526:Dnah1	UTSW	14	31,007,955 (GRCm39)	missense	probably benign	0.05
R4650:Dnah1	UTSW	14	31,006,844 (GRCm39)	splice site	probably null
R4723:Dnah1	UTSW	14	30,994,899 (GRCm39)	missense	probably damaging	1.00
R4748:Dnah1	UTSW	14	31,041,902 (GRCm39)	missense	probably benign
R4783:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4784:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4785:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4843:Dnah1	UTSW	14	30,986,920 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah1	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
R4897:Dnah1	UTSW	14	30,989,496 (GRCm39)	missense	probably damaging	1.00
R4911:Dnah1	UTSW	14	31,017,280 (GRCm39)	missense	probably damaging	1.00
R4985:Dnah1	UTSW	14	31,008,855 (GRCm39)	missense	probably null	1.00
R5070:Dnah1	UTSW	14	31,004,375 (GRCm39)	missense	probably benign	0.05
R5128:Dnah1	UTSW	14	31,018,152 (GRCm39)	splice site	probably null
R5409:Dnah1	UTSW	14	30,985,212 (GRCm39)	missense	probably damaging	1.00
R5436:Dnah1	UTSW	14	31,038,704 (GRCm39)	missense	probably benign
R5481:Dnah1	UTSW	14	31,030,828 (GRCm39)	missense	possibly damaging	0.55
R5550:Dnah1	UTSW	14	31,038,665 (GRCm39)	missense	probably benign	0.00
R5555:Dnah1	UTSW	14	31,012,776 (GRCm39)	missense	probably damaging	0.99
R5566:Dnah1	UTSW	14	30,996,323 (GRCm39)	missense	probably benign	0.35
R5623:Dnah1	UTSW	14	31,007,980 (GRCm39)	missense	possibly damaging	0.62
R5701:Dnah1	UTSW	14	30,996,001 (GRCm39)	missense	probably damaging	1.00
R5751:Dnah1	UTSW	14	31,032,863 (GRCm39)	missense	probably benign	0.00
R5823:Dnah1	UTSW	14	30,988,375 (GRCm39)	missense	possibly damaging	0.92
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6090:Dnah1	UTSW	14	30,991,382 (GRCm39)	missense	possibly damaging	0.83
R6139:Dnah1	UTSW	14	31,007,984 (GRCm39)	missense	probably benign	0.02
R6145:Dnah1	UTSW	14	31,022,927 (GRCm39)	missense	probably benign	0.07
R6306:Dnah1	UTSW	14	31,026,544 (GRCm39)	missense	probably damaging	0.97
R6376:Dnah1	UTSW	14	30,997,565 (GRCm39)	missense	probably damaging	1.00
R6451:Dnah1	UTSW	14	31,022,765 (GRCm39)	missense	probably benign	0.08
R6549:Dnah1	UTSW	14	30,991,340 (GRCm39)	missense	probably damaging	1.00
R6748:Dnah1	UTSW	14	31,021,945 (GRCm39)	missense	probably damaging	0.99
R6826:Dnah1	UTSW	14	31,008,247 (GRCm39)	missense	probably benign	0.00
R6870:Dnah1	UTSW	14	30,993,018 (GRCm39)	nonsense	probably null
R6932:Dnah1	UTSW	14	31,009,733 (GRCm39)	missense	probably damaging	1.00
R6944:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R7033:Dnah1	UTSW	14	30,986,882 (GRCm39)	missense	probably damaging	1.00
R7078:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R7133:Dnah1	UTSW	14	31,008,033 (GRCm39)	missense	probably benign
R7136:Dnah1	UTSW	14	31,020,613 (GRCm39)	missense	probably damaging	1.00
R7203:Dnah1	UTSW	14	30,996,339 (GRCm39)	missense	probably benign
R7241:Dnah1	UTSW	14	30,986,896 (GRCm39)	missense	probably benign	0.00
R7260:Dnah1	UTSW	14	30,991,343 (GRCm39)	missense	probably damaging	1.00
R7264:Dnah1	UTSW	14	30,991,851 (GRCm39)	missense	probably benign
R7291:Dnah1	UTSW	14	31,020,662 (GRCm39)	missense	probably damaging	1.00
R7293:Dnah1	UTSW	14	31,009,820 (GRCm39)	missense	probably damaging	1.00
R7300:Dnah1	UTSW	14	30,991,798 (GRCm39)	missense	probably benign	0.05
R7319:Dnah1	UTSW	14	31,018,551 (GRCm39)	missense	probably benign	0.02
R7323:Dnah1	UTSW	14	31,020,664 (GRCm39)	missense	probably damaging	1.00
R7472:Dnah1	UTSW	14	31,022,748 (GRCm39)	missense	possibly damaging	0.80
R7472:Dnah1	UTSW	14	30,983,547 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah1	UTSW	14	31,037,079 (GRCm39)	nonsense	probably null
R7526:Dnah1	UTSW	14	31,009,833 (GRCm39)	missense	possibly damaging	0.49
R7560:Dnah1	UTSW	14	31,026,940 (GRCm39)	missense	probably benign
R7574:Dnah1	UTSW	14	31,041,865 (GRCm39)	missense	probably benign	0.00
R7617:Dnah1	UTSW	14	31,006,739 (GRCm39)	missense	possibly damaging	0.80
R7620:Dnah1	UTSW	14	31,025,863 (GRCm39)	missense	possibly damaging	0.47
R7692:Dnah1	UTSW	14	31,014,295 (GRCm39)	missense	probably benign	0.00
R7702:Dnah1	UTSW	14	31,032,866 (GRCm39)	missense	probably benign
R7786:Dnah1	UTSW	14	30,984,478 (GRCm39)	missense	probably damaging	1.00
R7984:Dnah1	UTSW	14	30,989,772 (GRCm39)	missense	probably damaging	1.00
R8002:Dnah1	UTSW	14	31,020,679 (GRCm39)	missense	probably damaging	1.00
R8022:Dnah1	UTSW	14	30,986,971 (GRCm39)	missense	probably damaging	1.00
R8032:Dnah1	UTSW	14	30,993,505 (GRCm39)	missense	probably damaging	1.00
R8099:Dnah1	UTSW	14	31,024,321 (GRCm39)	missense	probably benign	0.00
R8171:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R8263:Dnah1	UTSW	14	31,015,134 (GRCm39)	missense	probably damaging	1.00
R8274:Dnah1	UTSW	14	31,017,531 (GRCm39)	missense	probably benign	0.00
R8345:Dnah1	UTSW	14	30,986,551 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8353:Dnah1	UTSW	14	31,005,159 (GRCm39)	missense	probably benign
R8356:Dnah1	UTSW	14	30,994,972 (GRCm39)	missense	probably benign	0.00
R8376:Dnah1	UTSW	14	31,023,303 (GRCm39)	missense	probably damaging	1.00
R8448:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8461:Dnah1	UTSW	14	31,027,915 (GRCm39)	missense	probably benign	0.00
R8534:Dnah1	UTSW	14	31,023,805 (GRCm39)	missense	probably benign	0.16
R8544:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R8679:Dnah1	UTSW	14	30,989,767 (GRCm39)	missense	possibly damaging	0.77
R8716:Dnah1	UTSW	14	30,989,941 (GRCm39)	critical splice donor site	probably benign
R8750:Dnah1	UTSW	14	31,026,924 (GRCm39)	missense	probably benign	0.30
R8808:Dnah1	UTSW	14	31,008,771 (GRCm39)	missense	probably benign
R8821:Dnah1	UTSW	14	31,018,455 (GRCm39)	missense	probably benign
R8887:Dnah1	UTSW	14	31,032,997 (GRCm39)	missense	probably damaging	1.00
R8948:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8950:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8955:Dnah1	UTSW	14	31,007,950 (GRCm39)	missense	probably benign
R8987:Dnah1	UTSW	14	31,033,704 (GRCm39)	missense	possibly damaging	0.93
R8998:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R8999:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R9015:Dnah1	UTSW	14	30,986,316 (GRCm39)	missense	probably damaging	0.96
R9031:Dnah1	UTSW	14	31,001,128 (GRCm39)	missense	probably benign
R9088:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably benign	0.04
R9096:Dnah1	UTSW	14	30,983,027 (GRCm39)	missense	probably damaging	0.99
R9117:Dnah1	UTSW	14	31,033,581 (GRCm39)	splice site	probably benign
R9157:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9296:Dnah1	UTSW	14	30,996,011 (GRCm39)	critical splice acceptor site	probably null
R9313:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9325:Dnah1	UTSW	14	30,998,160 (GRCm39)	missense	possibly damaging	0.69
R9352:Dnah1	UTSW	14	31,038,620 (GRCm39)	missense	probably benign	0.00
R9411:Dnah1	UTSW	14	31,018,256 (GRCm39)	missense	probably damaging	1.00
R9429:Dnah1	UTSW	14	30,997,499 (GRCm39)	nonsense	probably null
R9452:Dnah1	UTSW	14	31,018,448 (GRCm39)	missense	probably benign	0.35
R9562:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9565:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9616:Dnah1	UTSW	14	31,026,400 (GRCm39)	missense	probably null	0.20
R9621:Dnah1	UTSW	14	31,016,772 (GRCm39)	missense	probably damaging	1.00
R9677:Dnah1	UTSW	14	31,029,821 (GRCm39)	missense	probably benign	0.00
R9723:Dnah1	UTSW	14	30,987,946 (GRCm39)	missense	probably damaging	1.00
R9758:Dnah1	UTSW	14	30,985,395 (GRCm39)	missense	probably damaging	0.98
RF006:Dnah1	UTSW	14	31,029,832 (GRCm39)	missense	probably benign	0.08
Z1088:Dnah1	UTSW	14	31,026,768 (GRCm39)	missense	probably benign	0.17

Predicted Primers

PCR Primer
(F):5'- TTGGACATGACCTTTGGCCTC -3'
(R):5'- ATGAAGGCCAGTGTGCATGAC -3'

Sequencing Primer
(F):5'- TCGTCCAGGCTTGATGCAG -3'
(R):5'- CCAGTGTGCATGACATCATTGAG -3'

Posted On

2021-04-30