Incidental Mutation 'R8794:Ptprk'
| ID |
671123 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ptprk
|
| Ensembl Gene |
ENSMUSG00000019889 |
| Gene Name |
protein tyrosine phosphatase receptor type K |
| Synonyms |
RPTPkappa, PTPk |
| MMRRC Submission |
068723-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8794 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
27950816-28473393 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 28139504 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Stop codon
at position 76
(Y76*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000151986
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166468]
[ENSMUST00000218276]
[ENSMUST00000218359]
|
| AlphaFold |
P35822 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000166468
AA Change: Y76*
|
| SMART Domains |
Protein: ENSMUSP00000126279
Gene: ENSMUSG00000019889
AA Change: Y76*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
MAM
|
30 |
193 |
1.61e-73 |
SMART |
|
IG
|
200 |
288 |
2.16e-8 |
SMART |
|
FN3
|
290 |
373 |
1.48e-4 |
SMART |
|
FN3
|
389 |
475 |
4.24e1 |
SMART |
|
FN3
|
491 |
579 |
3.32e-7 |
SMART |
|
transmembrane domain
|
753 |
774 |
N/A |
INTRINSIC |
|
PTPc
|
898 |
1161 |
3.56e-132 |
SMART |
|
PTPc
|
1190 |
1455 |
2.68e-86 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000218276
AA Change: Y76*
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000218359
AA Change: Y76*
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218584
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218633
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219478
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219761
|
| Meta Mutation Damage Score |
0.9754 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.9%
- 20x: 99.6%
|
| Validation Efficiency |
100% (86/86) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
T |
A |
17: 9,226,939 (GRCm39) |
V498D |
unknown |
Het |
| Actn1 |
C |
T |
12: 80,245,754 (GRCm39) |
|
probably benign |
Het |
| Actrt2 |
T |
C |
4: 154,751,176 (GRCm39) |
E320G |
probably damaging |
Het |
| Adamts7 |
C |
T |
9: 90,076,239 (GRCm39) |
Q1265* |
probably null |
Het |
| Adra1a |
A |
G |
14: 66,875,064 (GRCm39) |
N13S |
probably benign |
Het |
| Alpk3 |
G |
T |
7: 80,707,403 (GRCm39) |
R9L |
unknown |
Het |
| Ankrd42 |
A |
G |
7: 92,263,674 (GRCm39) |
F225L |
probably benign |
Het |
| C3 |
T |
C |
17: 57,528,011 (GRCm39) |
E736G |
probably benign |
Het |
| Ccng1 |
A |
G |
11: 40,644,826 (GRCm39) |
S24P |
probably benign |
Het |
| Cdc42bpa |
A |
T |
1: 179,894,816 (GRCm39) |
N332I |
probably damaging |
Het |
| Cep131 |
G |
A |
11: 119,972,074 (GRCm39) |
P90S |
probably benign |
Het |
| Chd8 |
A |
G |
14: 52,441,904 (GRCm39) |
S2154P |
probably damaging |
Het |
| Cilp |
A |
G |
9: 65,186,535 (GRCm39) |
S877G |
probably benign |
Het |
| Clic6 |
T |
A |
16: 92,324,987 (GRCm39) |
S382T |
possibly damaging |
Het |
| Coq8a |
G |
T |
1: 180,006,773 (GRCm39) |
P85Q |
probably benign |
Het |
| Creb3l4 |
A |
G |
3: 90,145,225 (GRCm39) |
I309T |
probably benign |
Het |
| Cux2 |
T |
C |
5: 122,007,306 (GRCm39) |
E785G |
probably benign |
Het |
| Cyfip2 |
A |
G |
11: 46,144,800 (GRCm39) |
F685L |
possibly damaging |
Het |
| Epha6 |
T |
C |
16: 60,026,035 (GRCm39) |
D469G |
probably benign |
Het |
| Erc1 |
A |
T |
6: 119,607,616 (GRCm39) |
V962E |
probably damaging |
Het |
| Esrrb |
A |
T |
12: 86,517,038 (GRCm39) |
S57C |
probably damaging |
Het |
| Fam169a |
A |
G |
13: 97,250,628 (GRCm39) |
T320A |
possibly damaging |
Het |
| Farsb |
C |
T |
1: 78,401,678 (GRCm39) |
|
probably benign |
Het |
| Frem3 |
T |
C |
8: 81,338,907 (GRCm39) |
V400A |
probably damaging |
Het |
| Frem3 |
A |
T |
8: 81,342,851 (GRCm39) |
M1715L |
probably benign |
Het |
| Frmpd1 |
A |
G |
4: 45,279,632 (GRCm39) |
T786A |
probably benign |
Het |
| Gapvd1 |
A |
T |
2: 34,594,330 (GRCm39) |
S886T |
possibly damaging |
Het |
| Gba2 |
A |
G |
4: 43,568,077 (GRCm39) |
S737P |
probably damaging |
Het |
| Gm525 |
A |
G |
11: 88,979,479 (GRCm39) |
N85S |
probably damaging |
Het |
| Gnpda1 |
T |
A |
18: 38,465,091 (GRCm39) |
D175V |
probably benign |
Het |
| Heatr5b |
T |
C |
17: 79,123,015 (GRCm39) |
I655V |
probably benign |
Het |
| Hmcn1 |
G |
A |
1: 150,591,469 (GRCm39) |
T1910I |
probably benign |
Het |
| Idh1 |
CA |
CAA |
1: 65,204,347 (GRCm39) |
|
probably null |
Het |
| Ier2 |
A |
T |
8: 85,389,096 (GRCm39) |
D95E |
probably damaging |
Het |
| Ifi208 |
A |
G |
1: 173,523,370 (GRCm39) |
R547G |
possibly damaging |
Het |
| Itih3 |
T |
A |
14: 30,634,854 (GRCm39) |
S639C |
possibly damaging |
Het |
| Kif19b |
A |
G |
5: 140,461,785 (GRCm39) |
E529G |
probably damaging |
Het |
| Marchf7 |
G |
A |
2: 60,074,015 (GRCm39) |
|
probably null |
Het |
| Mep1b |
A |
C |
18: 21,224,325 (GRCm39) |
T373P |
probably damaging |
Het |
| Mlh3 |
G |
A |
12: 85,282,497 (GRCm39) |
P1379S |
probably damaging |
Het |
| Nav3 |
T |
A |
10: 109,605,032 (GRCm39) |
K1014* |
probably null |
Het |
| Nme1 |
A |
T |
11: 93,851,658 (GRCm39) |
F78I |
probably benign |
Het |
| Nos3 |
T |
A |
5: 24,576,745 (GRCm39) |
V458D |
probably damaging |
Het |
| Noxa1 |
A |
G |
2: 24,984,852 (GRCm39) |
F29L |
probably benign |
Het |
| Nrcam |
G |
A |
12: 44,624,958 (GRCm39) |
G1055D |
probably benign |
Het |
| Nutf2 |
A |
T |
8: 106,602,171 (GRCm39) |
|
probably benign |
Het |
| Oog3 |
A |
G |
4: 143,884,556 (GRCm39) |
I460T |
probably benign |
Het |
| Or4b1b |
A |
T |
2: 90,112,150 (GRCm39) |
Y256* |
probably null |
Het |
| Or4c113 |
T |
C |
2: 88,885,477 (GRCm39) |
M98V |
probably benign |
Het |
| Or5p78 |
A |
T |
7: 108,211,580 (GRCm39) |
D22V |
probably benign |
Het |
| Or7e175 |
A |
T |
9: 20,048,630 (GRCm39) |
M73L |
possibly damaging |
Het |
| Pde2a |
A |
T |
7: 101,155,136 (GRCm39) |
Y559F |
possibly damaging |
Het |
| Pde6d |
G |
A |
1: 86,475,209 (GRCm39) |
Q61* |
probably null |
Het |
| Pdpr |
A |
G |
8: 111,852,240 (GRCm39) |
T536A |
possibly damaging |
Het |
| Pias4 |
T |
A |
10: 80,999,846 (GRCm39) |
K69M |
probably damaging |
Het |
| Pigo |
A |
T |
4: 43,023,787 (GRCm39) |
D188E |
possibly damaging |
Het |
| Pik3r2 |
A |
G |
8: 71,224,007 (GRCm39) |
V270A |
probably benign |
Het |
| Plod2 |
T |
A |
9: 92,482,801 (GRCm39) |
W456R |
probably damaging |
Het |
| Pmpcb |
T |
C |
5: 21,961,832 (GRCm39) |
V450A |
probably benign |
Het |
| Poln |
G |
A |
5: 34,286,871 (GRCm39) |
T99I |
possibly damaging |
Het |
| Prg2 |
A |
G |
2: 84,812,404 (GRCm39) |
D38G |
possibly damaging |
Het |
| Psmd7 |
A |
C |
8: 108,310,831 (GRCm39) |
Y138D |
probably damaging |
Het |
| Ranbp2 |
T |
A |
10: 58,328,414 (GRCm39) |
V2810E |
probably damaging |
Het |
| Rgma |
A |
T |
7: 73,067,648 (GRCm39) |
H411L |
probably damaging |
Het |
| Sapcd1 |
T |
C |
17: 35,246,814 (GRCm39) |
T25A |
probably damaging |
Het |
| Serpinb6e |
T |
C |
13: 34,024,977 (GRCm39) |
I105V |
possibly damaging |
Het |
| Serpinb9f |
A |
T |
13: 33,513,396 (GRCm39) |
T158S |
probably benign |
Het |
| Sirpb1b |
T |
A |
3: 15,613,843 (GRCm39) |
T80S |
probably benign |
Het |
| Skint6 |
A |
T |
4: 113,049,869 (GRCm39) |
S265R |
possibly damaging |
Het |
| Slc23a2 |
A |
T |
2: 131,902,629 (GRCm39) |
F524L |
probably benign |
Het |
| Slc2a13 |
C |
A |
15: 91,234,302 (GRCm39) |
G345C |
probably damaging |
Het |
| Sp110 |
A |
G |
1: 85,511,231 (GRCm39) |
|
probably null |
Het |
| Srcin1 |
A |
G |
11: 97,439,803 (GRCm39) |
V109A |
probably benign |
Het |
| Tfcp2l1 |
A |
G |
1: 118,560,118 (GRCm39) |
N70S |
probably damaging |
Het |
| Tmem30c |
T |
A |
16: 57,090,553 (GRCm39) |
H218L |
probably benign |
Het |
| Tmprss11d |
G |
A |
5: 86,486,680 (GRCm39) |
T70I |
probably damaging |
Het |
| Tnpo2 |
A |
T |
8: 85,765,114 (GRCm39) |
Q32L |
probably benign |
Het |
| Trav16n |
A |
C |
14: 53,588,867 (GRCm39) |
T48P |
probably damaging |
Het |
| Ufc1 |
A |
G |
1: 171,117,095 (GRCm39) |
Y110H |
probably damaging |
Het |
| Wars2 |
A |
G |
3: 99,123,888 (GRCm39) |
K250E |
probably damaging |
Het |
| Wdfy4 |
G |
T |
14: 32,869,049 (GRCm39) |
N326K |
probably benign |
Het |
| Xirp2 |
A |
T |
2: 67,341,557 (GRCm39) |
E1266V |
probably damaging |
Het |
| Zfp423 |
A |
C |
8: 88,507,857 (GRCm39) |
L829R |
probably damaging |
Het |
| Zfp735 |
A |
G |
11: 73,603,029 (GRCm39) |
K658E |
possibly damaging |
Het |
| Zscan12 |
T |
A |
13: 21,547,847 (GRCm39) |
C10S |
possibly damaging |
Het |
| Zswim3 |
T |
A |
2: 164,662,687 (GRCm39) |
M389K |
probably damaging |
Het |
|
| Other mutations in Ptprk |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00310:Ptprk
|
APN |
10 |
28,212,506 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL00533:Ptprk
|
APN |
10 |
28,461,971 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01062:Ptprk
|
APN |
10 |
28,456,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01295:Ptprk
|
APN |
10 |
28,351,174 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL01372:Ptprk
|
APN |
10 |
28,445,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01452:Ptprk
|
APN |
10 |
28,450,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01829:Ptprk
|
APN |
10 |
28,449,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01861:Ptprk
|
APN |
10 |
28,259,441 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01955:Ptprk
|
APN |
10 |
28,471,861 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02263:Ptprk
|
APN |
10 |
27,951,110 (GRCm39) |
missense |
unknown |
|
|
IGL02489:Ptprk
|
APN |
10 |
28,259,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02697:Ptprk
|
APN |
10 |
28,451,614 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02713:Ptprk
|
APN |
10 |
28,468,807 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02943:Ptprk
|
APN |
10 |
28,351,172 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03240:Ptprk
|
APN |
10 |
28,368,957 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03373:Ptprk
|
APN |
10 |
28,442,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
LCD18:Ptprk
|
UTSW |
10 |
28,450,983 (GRCm39) |
intron |
probably benign |
|
|
PIT4366001:Ptprk
|
UTSW |
10 |
28,462,015 (GRCm39) |
missense |
probably benign |
|
|
R0010:Ptprk
|
UTSW |
10 |
28,461,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0021:Ptprk
|
UTSW |
10 |
28,468,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0021:Ptprk
|
UTSW |
10 |
28,468,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0035:Ptprk
|
UTSW |
10 |
28,139,504 (GRCm39) |
nonsense |
probably null |
|
|
R0035:Ptprk
|
UTSW |
10 |
28,139,504 (GRCm39) |
nonsense |
probably null |
|
|
R0053:Ptprk
|
UTSW |
10 |
28,351,105 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0063:Ptprk
|
UTSW |
10 |
28,139,763 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0063:Ptprk
|
UTSW |
10 |
28,139,763 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0244:Ptprk
|
UTSW |
10 |
28,082,221 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0281:Ptprk
|
UTSW |
10 |
28,449,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0387:Ptprk
|
UTSW |
10 |
28,230,625 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0480:Ptprk
|
UTSW |
10 |
28,461,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0480:Ptprk
|
UTSW |
10 |
28,461,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0585:Ptprk
|
UTSW |
10 |
28,451,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Ptprk
|
UTSW |
10 |
27,951,132 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0684:Ptprk
|
UTSW |
10 |
28,359,294 (GRCm39) |
splice site |
probably benign |
|
|
R1073:Ptprk
|
UTSW |
10 |
28,372,943 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1377:Ptprk
|
UTSW |
10 |
28,462,022 (GRCm39) |
missense |
probably benign |
0.42 |
|
R1422:Ptprk
|
UTSW |
10 |
28,351,276 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1482:Ptprk
|
UTSW |
10 |
28,139,512 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1532:Ptprk
|
UTSW |
10 |
28,461,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1576:Ptprk
|
UTSW |
10 |
28,427,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1618:Ptprk
|
UTSW |
10 |
28,369,166 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1654:Ptprk
|
UTSW |
10 |
28,259,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1701:Ptprk
|
UTSW |
10 |
28,342,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1747:Ptprk
|
UTSW |
10 |
28,230,688 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R2033:Ptprk
|
UTSW |
10 |
28,468,763 (GRCm39) |
unclassified |
probably benign |
|
|
R2059:Ptprk
|
UTSW |
10 |
28,442,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2076:Ptprk
|
UTSW |
10 |
28,465,364 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2164:Ptprk
|
UTSW |
10 |
28,436,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2260:Ptprk
|
UTSW |
10 |
28,082,145 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2394:Ptprk
|
UTSW |
10 |
28,427,713 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2432:Ptprk
|
UTSW |
10 |
28,468,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2437:Ptprk
|
UTSW |
10 |
28,230,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Ptprk
|
UTSW |
10 |
28,351,074 (GRCm39) |
splice site |
probably benign |
|
|
R3037:Ptprk
|
UTSW |
10 |
28,456,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Ptprk
|
UTSW |
10 |
28,468,822 (GRCm39) |
missense |
probably benign |
|
|
R3162:Ptprk
|
UTSW |
10 |
28,468,822 (GRCm39) |
missense |
probably benign |
|
|
R3687:Ptprk
|
UTSW |
10 |
28,349,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3722:Ptprk
|
UTSW |
10 |
28,259,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3892:Ptprk
|
UTSW |
10 |
28,139,617 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3963:Ptprk
|
UTSW |
10 |
28,427,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4077:Ptprk
|
UTSW |
10 |
28,139,508 (GRCm39) |
missense |
probably benign |
|
|
R4079:Ptprk
|
UTSW |
10 |
28,139,508 (GRCm39) |
missense |
probably benign |
|
|
R4112:Ptprk
|
UTSW |
10 |
28,351,284 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4255:Ptprk
|
UTSW |
10 |
28,082,241 (GRCm39) |
missense |
probably benign |
0.14 |
|
R4523:Ptprk
|
UTSW |
10 |
28,342,048 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4651:Ptprk
|
UTSW |
10 |
28,139,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4652:Ptprk
|
UTSW |
10 |
28,139,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4828:Ptprk
|
UTSW |
10 |
28,436,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4829:Ptprk
|
UTSW |
10 |
28,456,480 (GRCm39) |
nonsense |
probably null |
|
|
R4883:Ptprk
|
UTSW |
10 |
28,464,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5004:Ptprk
|
UTSW |
10 |
28,462,059 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5013:Ptprk
|
UTSW |
10 |
28,427,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5092:Ptprk
|
UTSW |
10 |
28,468,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5126:Ptprk
|
UTSW |
10 |
28,451,640 (GRCm39) |
splice site |
probably null |
|
|
R5183:Ptprk
|
UTSW |
10 |
28,351,232 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5264:Ptprk
|
UTSW |
10 |
28,461,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5304:Ptprk
|
UTSW |
10 |
28,468,050 (GRCm39) |
splice site |
probably null |
|
|
R5330:Ptprk
|
UTSW |
10 |
28,463,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5474:Ptprk
|
UTSW |
10 |
28,372,926 (GRCm39) |
nonsense |
probably null |
|
|
R5516:Ptprk
|
UTSW |
10 |
28,372,926 (GRCm39) |
nonsense |
probably null |
|
|
R5796:Ptprk
|
UTSW |
10 |
28,259,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5843:Ptprk
|
UTSW |
10 |
28,369,060 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5952:Ptprk
|
UTSW |
10 |
28,461,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6065:Ptprk
|
UTSW |
10 |
28,351,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6226:Ptprk
|
UTSW |
10 |
28,440,099 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6264:Ptprk
|
UTSW |
10 |
28,442,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Ptprk
|
UTSW |
10 |
28,471,807 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6843:Ptprk
|
UTSW |
10 |
28,467,978 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6860:Ptprk
|
UTSW |
10 |
28,210,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6869:Ptprk
|
UTSW |
10 |
28,349,055 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7214:Ptprk
|
UTSW |
10 |
28,450,905 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7307:Ptprk
|
UTSW |
10 |
28,465,004 (GRCm39) |
nonsense |
probably null |
|
|
R7349:Ptprk
|
UTSW |
10 |
28,468,834 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7442:Ptprk
|
UTSW |
10 |
28,450,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7585:Ptprk
|
UTSW |
10 |
28,436,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7661:Ptprk
|
UTSW |
10 |
28,342,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7694:Ptprk
|
UTSW |
10 |
28,465,366 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7740:Ptprk
|
UTSW |
10 |
28,372,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7810:Ptprk
|
UTSW |
10 |
28,468,853 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7831:Ptprk
|
UTSW |
10 |
28,444,404 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7836:Ptprk
|
UTSW |
10 |
28,449,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8049:Ptprk
|
UTSW |
10 |
28,259,565 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8235:Ptprk
|
UTSW |
10 |
28,465,037 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8274:Ptprk
|
UTSW |
10 |
28,456,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8286:Ptprk
|
UTSW |
10 |
28,444,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8372:Ptprk
|
UTSW |
10 |
28,230,688 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8727:Ptprk
|
UTSW |
10 |
28,442,541 (GRCm39) |
unclassified |
probably benign |
|
|
R8842:Ptprk
|
UTSW |
10 |
28,442,497 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8861:Ptprk
|
UTSW |
10 |
28,446,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8897:Ptprk
|
UTSW |
10 |
28,467,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8910:Ptprk
|
UTSW |
10 |
28,368,993 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8919:Ptprk
|
UTSW |
10 |
28,359,203 (GRCm39) |
nonsense |
probably null |
|
|
R8976:Ptprk
|
UTSW |
10 |
28,461,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8982:Ptprk
|
UTSW |
10 |
28,436,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Ptprk
|
UTSW |
10 |
28,461,928 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9135:Ptprk
|
UTSW |
10 |
28,456,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9308:Ptprk
|
UTSW |
10 |
28,450,850 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9317:Ptprk
|
UTSW |
10 |
28,230,731 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9475:Ptprk
|
UTSW |
10 |
28,210,476 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9585:Ptprk
|
UTSW |
10 |
28,369,147 (GRCm39) |
nonsense |
probably null |
|
|
R9625:Ptprk
|
UTSW |
10 |
28,462,006 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9700:Ptprk
|
UTSW |
10 |
28,456,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Ptprk
|
UTSW |
10 |
28,139,608 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
Z1177:Ptprk
|
UTSW |
10 |
28,369,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATGGATCTACGTGATGTCTTGAC -3'
(R):5'- ACCAGTGAATCCAGTTACATTCC -3'
Sequencing Primer
(F):5'- GACTGATATTTTTCTATGGCCCTG -3'
(R):5'- TCCAAATTGGATTAGCAAGAGGTCC -3'
|
| Posted On |
2021-04-30 |
Incidental Mutation