Incidental Mutation 'R8798:Ly75'
| ID |
671346 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| MMRRC Submission |
068724-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8798 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
60292103-60383303 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 60323926 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 1059
(F1059S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028362
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028362
AA Change: F1059S
PolyPhen 2
Score 0.317 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: F1059S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112533
AA Change: F1059S
PolyPhen 2
Score 0.061 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: F1059S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (74/74) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700011L22Rik |
G |
A |
8: 79,210,751 (GRCm38) |
R176* |
probably null |
Het |
| 2610044O15Rik8 |
G |
A |
8: 129,219,298 (GRCm38) |
H349Y |
probably damaging |
Het |
| 4921539E11Rik |
A |
C |
4: 103,266,377 (GRCm38) |
|
probably benign |
Het |
| A430078G23Rik |
T |
A |
8: 3,364,645 (GRCm38) |
Y8N |
probably benign |
Het |
| Abcc2 |
A |
G |
19: 43,808,666 (GRCm38) |
N492S |
probably benign |
Het |
| Acox1 |
T |
C |
11: 116,174,357 (GRCm38) |
Y624C |
probably damaging |
Het |
| Aff4 |
T |
C |
11: 53,400,508 (GRCm38) |
|
probably benign |
Het |
| Ak9 |
T |
A |
10: 41,382,851 (GRCm38) |
D781E |
|
Het |
| Arfgef3 |
T |
C |
10: 18,647,051 (GRCm38) |
D409G |
probably damaging |
Het |
| Blnk |
A |
G |
19: 40,962,351 (GRCm38) |
Y119H |
probably damaging |
Het |
| Brsk2 |
T |
C |
7: 141,987,864 (GRCm38) |
L310P |
probably damaging |
Het |
| Cit |
T |
A |
5: 115,969,043 (GRCm38) |
L1078Q |
probably damaging |
Het |
| Cpn1 |
A |
T |
19: 43,986,236 (GRCm38) |
V18D |
possibly damaging |
Het |
| Csmd3 |
A |
T |
15: 47,731,986 (GRCm38) |
Y1115N |
|
Het |
| Dnah9 |
A |
C |
11: 65,905,231 (GRCm38) |
V3589G |
probably damaging |
Het |
| Dpp9 |
T |
C |
17: 56,199,037 (GRCm38) |
Y454C |
probably damaging |
Het |
| Eif3i |
A |
G |
4: 129,596,924 (GRCm38) |
V67A |
probably benign |
Het |
| Eif6 |
T |
C |
2: 155,822,966 (GRCm38) |
N200S |
probably damaging |
Het |
| Fbxo10 |
T |
C |
4: 45,051,605 (GRCm38) |
H502R |
possibly damaging |
Het |
| Fcer1a |
A |
G |
1: 173,225,480 (GRCm38) |
Y50H |
probably benign |
Het |
| Filip1 |
G |
A |
9: 79,820,090 (GRCm38) |
H416Y |
possibly damaging |
Het |
| Frmpd1 |
A |
T |
4: 45,285,424 (GRCm38) |
N1415I |
possibly damaging |
Het |
| Gdpgp1 |
C |
T |
7: 80,238,977 (GRCm38) |
P252L |
probably damaging |
Het |
| Gm340 |
C |
T |
19: 41,585,259 (GRCm38) |
R818W |
probably damaging |
Het |
| Gsap |
T |
C |
5: 21,271,250 (GRCm38) |
|
probably null |
Het |
| Hgs |
T |
C |
11: 120,480,112 (GRCm38) |
V598A |
probably benign |
Het |
| Irf2 |
G |
T |
8: 46,807,314 (GRCm38) |
V94L |
probably benign |
Het |
| Kalrn |
G |
T |
16: 33,982,855 (GRCm38) |
H2675Q |
possibly damaging |
Het |
| Klhl33 |
C |
A |
14: 50,893,108 (GRCm38) |
A50S |
possibly damaging |
Het |
| Klk1b11 |
T |
C |
7: 43,995,948 (GRCm38) |
I15T |
probably benign |
Het |
| Lrrn3 |
A |
G |
12: 41,453,175 (GRCm38) |
M381T |
possibly damaging |
Het |
| Ltbr |
A |
G |
6: 125,307,295 (GRCm38) |
Y395H |
probably benign |
Het |
| Ltf |
A |
G |
9: 111,023,760 (GRCm38) |
|
probably benign |
Het |
| Lypd6 |
T |
A |
2: 50,188,762 (GRCm38) |
I90N |
possibly damaging |
Het |
| Map1a |
G |
A |
2: 121,302,287 (GRCm38) |
V1195M |
probably benign |
Het |
| Mb21d1 |
G |
A |
9: 78,443,066 (GRCm38) |
R5C |
probably benign |
Het |
| Mroh2b |
A |
T |
15: 4,948,709 (GRCm38) |
I1320F |
probably damaging |
Het |
| Mug2 |
A |
G |
6: 122,081,610 (GRCm38) |
T1324A |
probably damaging |
Het |
| Mylk |
G |
A |
16: 34,899,402 (GRCm38) |
V562M |
possibly damaging |
Het |
| Myo15b |
G |
A |
11: 115,863,406 (GRCm38) |
G911R |
|
Het |
| Neo1 |
A |
G |
9: 58,913,166 (GRCm38) |
Y825H |
probably damaging |
Het |
| Nfat5 |
T |
G |
8: 107,347,689 (GRCm38) |
V343G |
probably damaging |
Het |
| Nlrp2 |
A |
T |
7: 5,327,888 (GRCm38) |
I503K |
possibly damaging |
Het |
| Olfr180 |
A |
T |
16: 58,915,944 (GRCm38) |
D232E |
probably benign |
Het |
| Olfr270 |
C |
A |
4: 52,970,790 (GRCm38) |
H56Q |
possibly damaging |
Het |
| Olfr924 |
G |
A |
9: 38,848,917 (GRCm38) |
E268K |
probably benign |
Het |
| Olfr975 |
G |
A |
9: 39,950,717 (GRCm38) |
T18I |
probably benign |
Het |
| Pdcl2 |
T |
C |
5: 76,325,100 (GRCm38) |
D7G |
probably damaging |
Het |
| Phyh |
C |
T |
2: 4,919,082 (GRCm38) |
R5C |
probably damaging |
Het |
| Prr11 |
A |
C |
11: 87,106,055 (GRCm38) |
S28A |
unknown |
Het |
| Psmd13 |
T |
A |
7: 140,897,750 (GRCm38) |
L190* |
probably null |
Het |
| Ptx4 |
A |
G |
17: 25,124,742 (GRCm38) |
D322G |
probably damaging |
Het |
| Rnf40 |
T |
C |
7: 127,589,782 (GRCm38) |
L109P |
probably damaging |
Het |
| Rrp1 |
T |
C |
10: 78,409,190 (GRCm38) |
T102A |
probably damaging |
Het |
| Sema4a |
T |
G |
3: 88,436,697 (GRCm38) |
D749A |
possibly damaging |
Het |
| Serpina3f |
A |
T |
12: 104,217,443 (GRCm38) |
D188V |
probably benign |
Het |
| Smarca5 |
C |
A |
8: 80,716,508 (GRCm38) |
A570S |
probably damaging |
Het |
| Spocd1 |
G |
C |
4: 129,930,204 (GRCm38) |
|
probably null |
Het |
| Stard9 |
G |
A |
2: 120,704,731 (GRCm38) |
G3823D |
probably benign |
Het |
| Suco |
A |
G |
1: 161,820,435 (GRCm38) |
L1094S |
probably damaging |
Het |
| Tcf7 |
T |
C |
11: 52,260,594 (GRCm38) |
D79G |
probably damaging |
Het |
| Tdrd12 |
A |
G |
7: 35,529,180 (GRCm38) |
M39T |
probably damaging |
Het |
| Thnsl1 |
A |
G |
2: 21,212,398 (GRCm38) |
N321S |
probably benign |
Het |
| Tmem132c |
T |
A |
5: 127,360,153 (GRCm38) |
Y235* |
probably null |
Het |
| Tnfaip6 |
T |
C |
2: 52,043,812 (GRCm38) |
F60L |
probably benign |
Het |
| Tnpo3 |
T |
C |
6: 29,572,621 (GRCm38) |
I411V |
probably benign |
Het |
| Trio |
A |
C |
15: 27,851,837 (GRCm38) |
V856G |
possibly damaging |
Het |
| Trpc2 |
C |
G |
7: 102,084,560 (GRCm38) |
R239G |
probably benign |
Het |
| Ttn |
C |
T |
2: 76,826,132 (GRCm38) |
V12502I |
unknown |
Het |
| Usf3 |
A |
G |
16: 44,220,173 (GRCm38) |
D1672G |
probably damaging |
Het |
| Usp24 |
A |
G |
4: 106,379,239 (GRCm38) |
N1011S |
probably benign |
Het |
| Vac14 |
A |
G |
8: 110,719,887 (GRCm38) |
E756G |
probably benign |
Het |
| Vmn2r41 |
A |
G |
7: 8,161,523 (GRCm38) |
L10P |
probably damaging |
Het |
| Xrcc5 |
T |
C |
1: 72,314,178 (GRCm38) |
M115T |
probably damaging |
Het |
| Zfp827 |
G |
A |
8: 79,189,834 (GRCm38) |
|
probably benign |
Het |
| Zmym1 |
A |
T |
4: 127,049,871 (GRCm38) |
N241K |
possibly damaging |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,376,077 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,354,496 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,321,692 (GRCm38) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,376,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,301,015 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,338,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,299,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,311,764 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,352,356 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,354,452 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,358,507 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,293,781 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,383,182 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,321,900 (GRCm38) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,308,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,376,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,352,070 (GRCm38) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,352,352 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,339,457 (GRCm38) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,318,319 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,306,404 (GRCm38) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,308,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,316,221 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,293,758 (GRCm38) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,368,757 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,327,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,314,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,311,777 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,349,913 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,334,554 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,352,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,354,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,330,773 (GRCm38) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,308,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,352,125 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,375,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,375,963 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,334,487 (GRCm38) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,365,111 (GRCm38) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,365,145 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,352,381 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,299,082 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,318,439 (GRCm38) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,383,146 (GRCm38) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,375,962 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,368,873 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,318,376 (GRCm38) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,308,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,306,405 (GRCm38) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,306,434 (GRCm38) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,376,184 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,323,852 (GRCm38) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,329,993 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,334,515 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,334,474 (GRCm38) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,334,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,293,827 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,365,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,332,934 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,314,228 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,318,385 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,334,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8799:Ly75
|
UTSW |
2 |
60,348,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,331,089 (GRCm38) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,358,559 (GRCm38) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,316,098 (GRCm38) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,330,725 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,327,941 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,338,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,323,840 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,306,328 (GRCm38) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,354,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,352,133 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,350,004 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCCAGTGCTCATCTTCCT -3'
(R):5'- AGTTAACTGCCATTTTCTAGGTCTCA -3'
Sequencing Primer
(F):5'- AGCTTACTTCAAATTTGGCTCG -3'
(R):5'- AGGTCTCAAATGTCCGTCATG -3'
|
| Posted On |
2021-04-30 |
Incidental Mutation