Incidental Mutation 'R8812:Vmn1r19'
ID672481
Institutional Source Beutler Lab
Gene Symbol Vmn1r19
Ensembl Gene ENSMUSG00000115799
Gene Namevomeronasal 1 receptor 19
SynonymsV1rc27
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.100) question?
Stock #R8812 (G1)
Quality Score225.009
Status Not validated
Chromosome6
Chromosomal Location57403780-57406034 bp(+) (GRCm38)
Type of Mutationstart gained
DNA Base Change (assembly) A to G at 57404451 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000087264 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000089830]
Predicted Effect probably benign
Transcript: ENSMUST00000089830
SMART Domains Protein: ENSMUSP00000087264
Gene: ENSMUSG00000115799

DomainStartEndE-ValueType
Pfam:V1R 28 293 6.6e-58 PFAM
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 100.0%
  • 10x: 99.8%
  • 20x: 99.2%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 81 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2210408I21Rik C A 13: 77,332,352 P1167Q probably damaging Het
Adcy10 A T 1: 165,551,298 Q885H probably damaging Het
Alkal2 C T 12: 30,890,056 L139F probably damaging Het
Ankrd17 A T 5: 90,293,203 M439K probably benign Het
Arl11 C A 14: 61,310,973 Y77* probably null Het
Bcas3 T C 11: 85,559,147 Y669H probably benign Het
Bpifb3 C T 2: 153,922,596 A136V probably benign Het
Btbd11 A G 10: 85,627,249 Q626R probably damaging Het
C87414 T C 5: 93,637,801 T207A possibly damaging Het
Ccne2 A G 4: 11,202,279 T345A probably benign Het
Ciz1 T C 2: 32,364,274 S76P probably benign Het
Clip4 A T 17: 71,800,805 K94* probably null Het
Cthrc1 G A 15: 39,084,471 R195H probably damaging Het
D430042O09Rik A C 7: 125,797,695 R309S probably benign Het
Ddx31 T C 2: 28,840,804 probably benign Het
Elf2 T A 3: 51,266,767 D113V possibly damaging Het
Esrrb A G 12: 86,488,550 N155S probably benign Het
Fam198b T C 3: 79,908,771 S363P possibly damaging Het
Flnb A G 14: 7,887,624 D478G probably benign Het
Galm T A 17: 80,127,786 L24H probably damaging Het
Gm14124 T A 2: 150,267,704 C105S possibly damaging Het
Gon4l G A 3: 88,895,007 G975D possibly damaging Het
Hspbp1 T G 7: 4,664,784 M237L probably benign Het
Ighv1-62-1 A T 12: 115,386,747 M100K probably damaging Het
Ipo8 A T 6: 148,775,077 D971E possibly damaging Het
Itgax C T 7: 128,133,807 A286V probably damaging Het
Jpt2 T C 17: 24,960,604 Q3R probably benign Het
Klrg2 A C 6: 38,636,903 L55R probably damaging Het
Lrp6 T A 6: 134,456,178 M1397L probably benign Het
Lrrc31 T A 3: 30,679,179 Q462L probably benign Het
Lyg2 T A 1: 37,909,973 I103F probably damaging Het
Map10 T C 8: 125,669,925 V19A probably damaging Het
Map1b T A 13: 99,432,815 M1133L unknown Het
Mrgpra4 A G 7: 47,981,733 V40A probably benign Het
Myh1 G A 11: 67,209,141 G626R probably benign Het
Myo9a T C 9: 59,779,747 V45A probably benign Het
Ncdn A G 4: 126,745,112 F638S possibly damaging Het
Ncs1 T A 2: 31,284,201 M121K probably damaging Het
Nf1 T C 11: 79,546,354 V16A probably damaging Het
Nktr T A 9: 121,750,251 D1128E unknown Het
Nup205 T G 6: 35,214,334 L1000R probably damaging Het
Obscn T C 11: 59,035,095 E5604G probably damaging Het
Olfr1240 A G 2: 89,439,865 V138A probably benign Het
Olfr1260 G T 2: 89,978,371 A198S possibly damaging Het
Olfr1370 T C 13: 21,073,050 N84D probably damaging Het
Olfr1446 A T 19: 12,890,196 V127E probably damaging Het
Olfr409-ps1 T A 11: 74,317,708 S228T unknown Het
Olfr615 G T 7: 103,560,609 C44F probably benign Het
Olfr834 A G 9: 18,988,516 H176R possibly damaging Het
Ovch2 T A 7: 107,793,255 I294F probably damaging Het
Ovch2 A T 7: 107,794,044 C207* probably null Het
P3h2 T A 16: 25,982,717 Y397F possibly damaging Het
Pappa A T 4: 65,204,929 I834F possibly damaging Het
Pcdha11 T C 18: 37,007,663 S782P probably benign Het
Pex1 T C 5: 3,631,614 V980A probably benign Het
Pik3c2a G T 7: 116,351,877 L1258I probably damaging Het
Pmp22 T A 11: 63,158,413 *161R probably null Het
Ppp1r26 T A 2: 28,451,180 M274K probably benign Het
Ppp6r2 T C 15: 89,283,072 V830A probably benign Het
Prss1 T A 6: 41,462,586 N84K probably benign Het
Rab3il1 G A 19: 10,026,777 A18T probably damaging Het
Sbf2 A T 7: 110,329,862 S1471T probably damaging Het
Setdb1 T A 3: 95,356,060 D45V probably damaging Het
Sik3 G T 9: 46,178,513 V275L probably benign Het
Skint6 C A 4: 112,988,952 M659I probably benign Het
Slc24a1 T A 9: 64,928,703 D714V unknown Het
Slc26a5 T A 5: 21,813,882 D653V probably damaging Het
Snrnp27 A T 6: 86,676,214 C141S probably benign Het
Stradb A G 1: 58,994,319 I380M probably benign Het
Sult1e1 T C 5: 87,587,642 Y59C probably benign Het
Tas2r122 C T 6: 132,711,739 A64T probably benign Het
Tep1 C T 14: 50,837,132 C1812Y probably damaging Het
Tln2 C A 9: 67,221,411 E1465D possibly damaging Het
Trio A T 15: 27,905,225 C152S unknown Het
Tro G A X: 150,655,559 S34L unknown Het
Vmn1r15 A G 6: 57,258,138 probably benign Het
Vmn1r75 A G 7: 11,880,703 T121A possibly damaging Het
Vmn2r32 A G 7: 7,474,670 F241L probably damaging Het
Vmn2r66 A G 7: 85,005,685 L472P probably damaging Het
Ylpm1 G T 12: 84,996,792 W101C unknown Het
Zdbf2 C A 1: 63,308,113 H1884N probably benign Het
Other mutations in Vmn1r19
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00948:Vmn1r19 APN 6 57405262 missense probably benign 0.03
IGL01287:Vmn1r19 APN 6 57405194 missense probably damaging 1.00
IGL01516:Vmn1r19 APN 6 57404872 missense probably benign 0.03
IGL01895:Vmn1r19 APN 6 57405260 missense probably benign 0.02
IGL02676:Vmn1r19 APN 6 57405040 missense possibly damaging 0.94
IGL03040:Vmn1r19 APN 6 57405362 missense unknown
IGL03087:Vmn1r19 APN 6 57404491 missense probably benign 0.01
PIT4802001:Vmn1r19 UTSW 6 57405052 missense probably damaging 1.00
R0319:Vmn1r19 UTSW 6 57404615 missense possibly damaging 0.93
R1368:Vmn1r19 UTSW 6 57404671 missense probably benign 0.01
R1997:Vmn1r19 UTSW 6 57405048 missense probably damaging 1.00
R2920:Vmn1r19 UTSW 6 57404924 missense probably benign 0.03
R3857:Vmn1r19 UTSW 6 57405113 missense possibly damaging 0.68
R4090:Vmn1r19 UTSW 6 57404735 missense probably damaging 1.00
R4547:Vmn1r19 UTSW 6 57404789 missense possibly damaging 0.56
R4823:Vmn1r19 UTSW 6 57405234 nonsense probably null
R4951:Vmn1r19 UTSW 6 57404942 missense probably benign 0.36
R5077:Vmn1r19 UTSW 6 57405041 missense probably benign 0.00
R5459:Vmn1r19 UTSW 6 57404490 nonsense probably null
R5625:Vmn1r19 UTSW 6 57405296 missense probably damaging 1.00
R5690:Vmn1r19 UTSW 6 57404795 missense probably benign 0.10
R5761:Vmn1r19 UTSW 6 57405353 missense unknown
R6124:Vmn1r19 UTSW 6 57404617 missense probably benign 0.02
R6373:Vmn1r19 UTSW 6 57405332 missense unknown
R6476:Vmn1r19 UTSW 6 57404593 missense probably damaging 0.99
R6938:Vmn1r19 UTSW 6 57405007 missense possibly damaging 0.94
R7027:Vmn1r19 UTSW 6 57404490 nonsense probably null
R7359:Vmn1r19 UTSW 6 57405095 missense probably damaging 0.99
R7568:Vmn1r19 UTSW 6 57404828 missense possibly damaging 0.69
R7893:Vmn1r19 UTSW 6 57404679 missense probably damaging 1.00
R8481:Vmn1r19 UTSW 6 57404947 missense probably damaging 0.99
R8487:Vmn1r19 UTSW 6 57405181 missense probably benign 0.03
R8907:Vmn1r19 UTSW 6 57405006 missense probably benign
Predicted Primers PCR Primer
(F):5'- GGCTCTGGAAATTGAGATGAATC -3'
(R):5'- AGTTATCTCCTTCACTGAGGATCATC -3'

Sequencing Primer
(F):5'- CTGGAAATTGAGATGAATCCATTCC -3'
(R):5'- CCTTCACTGAGGATCATCATTATGTG -3'
Posted On2021-04-30