Mutagenetix > Incidental Mutation

Incidental Mutation 'R8816:Fcgbp'

672735

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

MMRRC Submission

068726-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8816 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

27770661-27820287 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 27784412 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Arginine at position 157 (S157R)

Ref Sequence

ENSEMBL: ENSMUSP00000075945 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

probably benign
Transcript: ENSMUST00000076648
AA Change: S157R

PolyPhen 2 Score 0.095 (Sensitivity: 0.93; Specificity: 0.85)

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: S157R

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000138392
AA Change: S157R

PolyPhen 2 Score 0.187 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: S157R

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 60 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca6	T	A	11: 110,127,513 (GRCm39)	H348L	probably benign	Het
Alpk1	A	T	3: 127,478,024 (GRCm39)	Y74*	probably null	Het
Ass1	T	C	2: 31,383,189 (GRCm39)		probably benign	Het
Atp8b4	C	T	2: 126,214,084 (GRCm39)		probably benign	Het
Atrn	C	A	2: 130,748,798 (GRCm39)	N106K	probably damaging	Het
Atrn	T	C	2: 130,846,494 (GRCm39)	V1256A	probably damaging	Het
Bicdl1	T	A	5: 115,862,804 (GRCm39)	Q150H	probably damaging	Het
Bltp3b	T	C	10: 89,626,597 (GRCm39)		probably benign	Het
Cdhr4	T	C	9: 107,872,791 (GRCm39)	V280A	possibly damaging	Het
Cfap54	C	T	10: 92,714,454 (GRCm39)	V2642I	unknown	Het
Chd2	T	C	7: 73,140,245 (GRCm39)	H661R	probably damaging	Het
Cntnap2	A	G	6: 46,833,076 (GRCm39)	D763G	possibly damaging	Het
Csnk1g2	T	C	10: 80,474,093 (GRCm39)	C160R	probably damaging	Het
Cyb5r4	T	C	9: 86,904,286 (GRCm39)	S19P	probably benign	Het
Cyp4a30b	G	A	4: 115,309,834 (GRCm39)	V12M	probably benign	Het
Dpp6	C	T	5: 27,930,711 (GRCm39)	P848S	probably benign	Het
Dzip1	T	C	14: 119,159,785 (GRCm39)	Y141C	probably benign	Het
Eif2b3	C	A	4: 116,928,052 (GRCm39)	Q424K	probably benign	Het
Fbxw14	G	A	9: 109,105,305 (GRCm39)	R287*	probably null	Het
Fmnl2	T	G	2: 53,004,214 (GRCm39)	V642G	unknown	Het
Gpr119	C	T	X: 47,762,276 (GRCm39)	R287Q	possibly damaging	Het
Grm7	C	T	6: 111,230,966 (GRCm39)	T463I	possibly damaging	Het
Haus4	G	A	14: 54,779,710 (GRCm39)	R305C	probably benign	Het
Htr1f	A	G	16: 64,746,537 (GRCm39)	S252P	probably benign	Het
Ino80b	T	C	6: 83,098,861 (GRCm39)	Q359R	probably damaging	Het
Itgad	C	A	7: 127,797,542 (GRCm39)	Y924*	probably null	Het
Itpr2	A	G	6: 146,142,710 (GRCm39)	Y1703H	probably damaging	Het
Kif5c	T	A	2: 49,584,799 (GRCm39)	V174E	probably damaging	Het
Kifc2	A	G	15: 76,548,371 (GRCm39)	E405G	probably damaging	Het
Klk1b3	T	C	7: 43,851,668 (GRCm39)	V242A	possibly damaging	Het
Kndc1	T	C	7: 139,517,909 (GRCm39)	F1615S	probably damaging	Het
Lmtk2	T	A	5: 144,112,793 (GRCm39)	L1171*	probably null	Het
Myh10	A	G	11: 68,693,778 (GRCm39)	E1530G	probably damaging	Het
Nav3	T	A	10: 109,699,721 (GRCm39)	S258C	possibly damaging	Het
Nudcd3	C	T	11: 6,100,587 (GRCm39)	G186S	probably damaging	Het
Or9s15	T	A	1: 92,524,768 (GRCm39)	C176S	probably damaging	Het
Otog	C	T	7: 45,950,905 (GRCm39)	S374F	possibly damaging	Het
P2ry2	T	A	7: 100,647,763 (GRCm39)	I181F	possibly damaging	Het
Pde11a	T	C	2: 76,121,577 (GRCm39)	I335V	probably benign	Het
Phyhip	A	C	14: 70,704,375 (GRCm39)	D198A	probably damaging	Het
Pik3r5	A	T	11: 68,385,060 (GRCm39)	Y655F	probably damaging	Het
Rab6a	T	C	7: 100,279,145 (GRCm39)	I95T	possibly damaging	Het
Sgsm1	T	C	5: 113,435,097 (GRCm39)	E99G	probably damaging	Het
Skint10	A	T	4: 112,603,892 (GRCm39)	F98L	probably benign	Het
Slc35c2	A	G	2: 165,119,378 (GRCm39)	S321P	probably benign	Het
Smyd1	T	A	6: 71,192,868 (GRCm39)	E447V	probably damaging	Het
Smyd4	T	C	11: 75,281,232 (GRCm39)	V235A	probably benign	Het
Sod2	A	G	17: 13,227,253 (GRCm39)	Y69C	probably benign	Het
Spns1	G	A	7: 125,971,593 (GRCm39)	S319F	possibly damaging	Het
Tfap2b	A	G	1: 19,284,337 (GRCm39)	S82G	probably benign	Het
Tln2	C	A	9: 67,128,693 (GRCm39)	E1465D	possibly damaging	Het
Tln2	A	G	9: 67,128,799 (GRCm39)	I1430T	probably damaging	Het
Trio	G	T	15: 27,741,357 (GRCm39)	N2680K	probably damaging	Het
Trmt10c	A	T	16: 55,854,522 (GRCm39)	V371D	probably damaging	Het
Trpm3	T	C	19: 22,965,580 (GRCm39)	S1692P	probably damaging	Het
Usb1	G	T	8: 96,071,984 (GRCm39)	C228F	probably benign	Het
Veph1	G	T	3: 66,065,646 (GRCm39)	H474N	probably benign	Het
Wls	A	G	3: 159,639,928 (GRCm39)	T520A	possibly damaging	Het
Ywhae	T	C	11: 75,623,878 (GRCm39)	Y9H	probably damaging	Het
Zranb3	C	T	1: 127,964,347 (GRCm39)	V127M	possibly damaging	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	27,784,555 (GRCm39)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	27,800,966 (GRCm39)	splice site	probably benign
IGL00335:Fcgbp	APN	7	27,785,560 (GRCm39)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	27,774,511 (GRCm39)	nonsense	probably null
IGL00491:Fcgbp	APN	7	27,792,827 (GRCm39)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	27,791,222 (GRCm39)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	27,789,072 (GRCm39)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	27,793,067 (GRCm39)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	27,803,388 (GRCm39)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	27,805,799 (GRCm39)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	27,774,629 (GRCm39)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	27,791,379 (GRCm39)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	27,774,660 (GRCm39)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	27,771,068 (GRCm39)	splice site	probably benign
IGL02377:Fcgbp	APN	7	27,806,395 (GRCm39)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	27,774,596 (GRCm39)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	27,789,378 (GRCm39)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	27,804,157 (GRCm39)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	27,800,599 (GRCm39)	intron	probably benign
IGL02631:Fcgbp	APN	7	27,784,723 (GRCm39)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	27,800,859 (GRCm39)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	27,816,783 (GRCm39)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	27,791,272 (GRCm39)	nonsense	probably null
IGL02971:Fcgbp	APN	7	27,800,898 (GRCm39)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	27,784,857 (GRCm39)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	27,789,342 (GRCm39)	missense	possibly damaging	0.76
bilge	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
swill	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	27,800,576 (GRCm39)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	27,774,698 (GRCm39)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	27,784,918 (GRCm39)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	27,790,879 (GRCm39)	splice site	probably benign
R0586:Fcgbp	UTSW	7	27,789,138 (GRCm39)	missense	probably damaging	1.00
R0981:Fcgbp	UTSW	7	27,784,535 (GRCm39)	nonsense	probably null
R0987:Fcgbp	UTSW	7	27,793,599 (GRCm39)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	27,819,950 (GRCm39)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	27,803,158 (GRCm39)	nonsense	probably null
R1474:Fcgbp	UTSW	7	27,791,273 (GRCm39)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	27,774,585 (GRCm39)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	27,800,674 (GRCm39)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	27,792,868 (GRCm39)	nonsense	probably null
R1772:Fcgbp	UTSW	7	27,804,600 (GRCm39)	missense	possibly damaging	0.90
R1804:Fcgbp	UTSW	7	27,785,564 (GRCm39)	missense	probably benign
R1808:Fcgbp	UTSW	7	27,784,515 (GRCm39)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	27,784,708 (GRCm39)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	27,806,518 (GRCm39)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	27,793,617 (GRCm39)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	27,819,785 (GRCm39)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	27,791,444 (GRCm39)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	27,806,628 (GRCm39)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	27,774,838 (GRCm39)	splice site	probably benign
R3037:Fcgbp	UTSW	7	27,802,127 (GRCm39)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	27,816,665 (GRCm39)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	27,800,701 (GRCm39)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	27,784,882 (GRCm39)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	27,806,721 (GRCm39)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	27,794,362 (GRCm39)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	27,813,383 (GRCm39)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	27,785,660 (GRCm39)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	27,789,237 (GRCm39)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	27,816,995 (GRCm39)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	27,785,528 (GRCm39)	splice site	probably null
R5219:Fcgbp	UTSW	7	27,803,510 (GRCm39)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	27,784,624 (GRCm39)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	27,793,099 (GRCm39)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	27,791,243 (GRCm39)	missense	probably damaging	1.00
R5335:Fcgbp	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	27,804,480 (GRCm39)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	27,784,738 (GRCm39)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	27,793,060 (GRCm39)	missense	probably benign
R5583:Fcgbp	UTSW	7	27,791,004 (GRCm39)	missense	probably damaging	1.00
R5698:Fcgbp	UTSW	7	27,791,447 (GRCm39)	missense	possibly damaging	0.95
R5780:Fcgbp	UTSW	7	27,784,643 (GRCm39)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	27,800,919 (GRCm39)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	27,784,928 (GRCm39)	splice site	probably benign
R5936:Fcgbp	UTSW	7	27,786,117 (GRCm39)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	27,819,959 (GRCm39)	missense	probably benign	0.05
R6091:Fcgbp	UTSW	7	27,804,390 (GRCm39)	missense	possibly damaging	0.90
R6372:Fcgbp	UTSW	7	27,806,433 (GRCm39)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	27,792,963 (GRCm39)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	27,785,695 (GRCm39)	nonsense	probably null
R6711:Fcgbp	UTSW	7	27,789,098 (GRCm39)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	27,802,637 (GRCm39)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	27,784,443 (GRCm39)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	27,789,129 (GRCm39)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	27,793,248 (GRCm39)	missense	probably benign
R6943:Fcgbp	UTSW	7	27,791,477 (GRCm39)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	27,791,358 (GRCm39)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	27,784,387 (GRCm39)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	27,803,446 (GRCm39)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	27,800,817 (GRCm39)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	27,792,861 (GRCm39)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	27,800,932 (GRCm39)	missense	probably damaging	1.00
R7426:Fcgbp	UTSW	7	27,785,949 (GRCm39)	missense	probably benign	0.00
R7459:Fcgbp	UTSW	7	27,806,710 (GRCm39)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	27,802,401 (GRCm39)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	27,789,099 (GRCm39)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	27,784,794 (GRCm39)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	27,785,724 (GRCm39)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	27,802,391 (GRCm39)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	27,790,928 (GRCm39)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	27,784,460 (GRCm39)	nonsense	probably null
R7820:Fcgbp	UTSW	7	27,819,784 (GRCm39)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	27,806,404 (GRCm39)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	27,816,632 (GRCm39)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	27,803,595 (GRCm39)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	27,813,389 (GRCm39)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	27,804,496 (GRCm39)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	27,784,507 (GRCm39)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	27,784,919 (GRCm39)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	27,791,174 (GRCm39)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	27,804,276 (GRCm39)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	27,793,614 (GRCm39)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	27,806,815 (GRCm39)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	27,789,231 (GRCm39)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	27,804,435 (GRCm39)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	27,785,978 (GRCm39)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	27,819,920 (GRCm39)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	27,805,621 (GRCm39)	missense	probably benign	0.05
R8905:Fcgbp	UTSW	7	27,785,934 (GRCm39)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	27,790,908 (GRCm39)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	27,791,277 (GRCm39)	missense	probably damaging	1.00
R9180:Fcgbp	UTSW	7	27,803,198 (GRCm39)	nonsense	probably null
R9262:Fcgbp	UTSW	7	27,819,952 (GRCm39)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	27,803,436 (GRCm39)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	27,790,937 (GRCm39)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	27,802,563 (GRCm39)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	27,800,832 (GRCm39)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	27,806,400 (GRCm39)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	27,793,000 (GRCm39)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	27,803,012 (GRCm39)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
X0028:Fcgbp	UTSW	7	27,803,445 (GRCm39)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	27,791,072 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,785,616 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,803,309 (GRCm39)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	27,792,770 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GCACTGGAGATAACTGTGGG -3'
(R):5'- AATTCCAAGGCATCGGGAGC -3'

Sequencing Primer
(F):5'- CTTCATGCACATCTTGGGGAAGAAC -3'
(R):5'- AGCCTGGTCCAAGTCAGG -3'

Posted On

2021-04-30