Incidental Mutation 'R8826:Sipa1l1'
| ID |
673482 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sipa1l1
|
| Ensembl Gene |
ENSMUSG00000042700 |
| Gene Name |
signal-induced proliferation-associated 1 like 1 |
| Synonyms |
Spar, 4931426N11Rik |
| MMRRC Submission |
068729-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8826 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
82216138-82498560 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 82389207 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 478
(K478E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131030
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000053969]
[ENSMUST00000166429]
[ENSMUST00000220963]
[ENSMUST00000222298]
[ENSMUST00000222714]
|
| AlphaFold |
Q8C0T5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000053969
AA Change: K478E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000061014
Gene: ENSMUSG00000042700
AA Change: K478E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
92 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
377 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
449 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
628 |
810 |
8.9e-70 |
PFAM |
|
PDZ
|
962 |
1028 |
2.63e-9 |
SMART |
|
low complexity region
|
1149 |
1164 |
N/A |
INTRINSIC |
|
low complexity region
|
1255 |
1279 |
N/A |
INTRINSIC |
|
low complexity region
|
1315 |
1328 |
N/A |
INTRINSIC |
|
low complexity region
|
1432 |
1447 |
N/A |
INTRINSIC |
|
Pfam:SPAR_C
|
1483 |
1727 |
4.4e-86 |
PFAM |
|
low complexity region
|
1731 |
1746 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166429
AA Change: K478E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000131030
Gene: ENSMUSG00000042700
AA Change: K478E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
92 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
377 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
449 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
628 |
816 |
1.3e-64 |
PFAM |
|
PDZ
|
962 |
1028 |
1.3e-11 |
SMART |
|
low complexity region
|
1149 |
1164 |
N/A |
INTRINSIC |
|
low complexity region
|
1255 |
1279 |
N/A |
INTRINSIC |
|
low complexity region
|
1315 |
1328 |
N/A |
INTRINSIC |
|
low complexity region
|
1432 |
1447 |
N/A |
INTRINSIC |
|
Pfam:DUF3401
|
1483 |
1727 |
1.8e-91 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000220963
AA Change: K478E
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000222298
AA Change: K478E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000222714
AA Change: K478E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
100% (91/91) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acta1 |
T |
C |
8: 124,619,978 (GRCm39) |
M121V |
probably damaging |
Het |
| AI987944 |
A |
T |
7: 41,024,627 (GRCm39) |
H120Q |
possibly damaging |
Het |
| Aldh9a1 |
C |
G |
1: 167,184,119 (GRCm39) |
P205A |
probably damaging |
Het |
| Ank2 |
A |
T |
3: 126,740,951 (GRCm39) |
N1644K |
unknown |
Het |
| Arfgef2 |
A |
T |
2: 166,677,386 (GRCm39) |
|
probably benign |
Het |
| Bpifb4 |
G |
T |
2: 153,783,817 (GRCm39) |
V54L |
probably benign |
Het |
| Cacna1c |
T |
A |
6: 118,711,836 (GRCm39) |
M456L |
|
Het |
| Cbln1 |
T |
C |
8: 88,198,420 (GRCm39) |
N95S |
probably benign |
Het |
| Ccl11 |
G |
T |
11: 81,953,044 (GRCm39) |
R67S |
possibly damaging |
Het |
| Cd200 |
G |
A |
16: 45,215,157 (GRCm39) |
R165C |
probably benign |
Het |
| Cd2bp2 |
A |
T |
7: 126,793,257 (GRCm39) |
M283K |
probably damaging |
Het |
| Cd86 |
G |
T |
16: 36,435,650 (GRCm39) |
L256I |
possibly damaging |
Het |
| Ces2f |
T |
A |
8: 105,679,734 (GRCm39) |
F409Y |
probably benign |
Het |
| Cisd3 |
A |
T |
11: 97,579,158 (GRCm39) |
Q100L |
probably damaging |
Het |
| Cntnap1 |
C |
T |
11: 101,077,655 (GRCm39) |
R1106C |
probably damaging |
Het |
| Col6a2 |
A |
T |
10: 76,439,433 (GRCm39) |
M777K |
probably damaging |
Het |
| Cp |
A |
G |
3: 20,039,739 (GRCm39) |
Y852C |
probably damaging |
Het |
| Ddx1 |
T |
C |
12: 13,277,332 (GRCm39) |
E523G |
probably damaging |
Het |
| Ddx60 |
T |
A |
8: 62,398,990 (GRCm39) |
D236E |
probably benign |
Het |
| Dnah9 |
A |
T |
11: 65,740,742 (GRCm39) |
F4148Y |
probably benign |
Het |
| Dusp6 |
G |
T |
10: 99,099,469 (GRCm39) |
|
probably benign |
Het |
| Eif2a |
C |
A |
3: 58,456,049 (GRCm39) |
Y349* |
probably null |
Het |
| Enpep |
G |
A |
3: 129,065,067 (GRCm39) |
T874I |
probably damaging |
Het |
| Eps15 |
A |
G |
4: 109,169,505 (GRCm39) |
D105G |
possibly damaging |
Het |
| Ess2 |
A |
T |
16: 17,722,954 (GRCm39) |
M320K |
probably damaging |
Het |
| Exosc10 |
G |
A |
4: 148,653,159 (GRCm39) |
|
probably null |
Het |
| Fam13b |
A |
T |
18: 34,631,070 (GRCm39) |
N36K |
probably damaging |
Het |
| Fanca |
T |
C |
8: 123,995,209 (GRCm39) |
D1431G |
probably benign |
Het |
| Fgg |
A |
G |
3: 82,921,625 (GRCm39) |
D436G |
probably benign |
Het |
| Fip1l1 |
C |
T |
5: 74,725,188 (GRCm39) |
T251I |
probably benign |
Het |
| Galnt2 |
A |
G |
8: 125,032,347 (GRCm39) |
N104S |
probably damaging |
Het |
| Gmip |
T |
C |
8: 70,268,748 (GRCm39) |
S458P |
possibly damaging |
Het |
| Herc2 |
A |
G |
7: 55,756,144 (GRCm39) |
D728G |
probably benign |
Het |
| Hif3a |
A |
G |
7: 16,788,671 (GRCm39) |
L100P |
probably damaging |
Het |
| Hmox2 |
C |
G |
16: 4,583,866 (GRCm39) |
P282R |
possibly damaging |
Het |
| Hook1 |
A |
T |
4: 95,880,432 (GRCm39) |
H90L |
probably benign |
Het |
| Igf2bp2 |
C |
A |
16: 21,883,866 (GRCm39) |
G473C |
probably damaging |
Het |
| Ip6k2 |
T |
C |
9: 108,675,379 (GRCm39) |
|
probably null |
Het |
| Ipo5 |
G |
T |
14: 121,157,366 (GRCm39) |
R68L |
probably damaging |
Het |
| Kif19b |
A |
G |
5: 140,455,434 (GRCm39) |
M347V |
probably damaging |
Het |
| Klhdc1 |
G |
T |
12: 69,305,392 (GRCm39) |
W234L |
probably damaging |
Het |
| Krt8 |
A |
G |
15: 101,909,870 (GRCm39) |
V178A |
possibly damaging |
Het |
| Lgi3 |
T |
A |
14: 70,768,712 (GRCm39) |
|
probably null |
Het |
| Litaf |
T |
G |
16: 10,784,421 (GRCm39) |
N30H |
probably benign |
Het |
| Lman2 |
C |
A |
13: 55,510,368 (GRCm39) |
W12L |
unknown |
Het |
| Macf1 |
A |
G |
4: 123,276,022 (GRCm39) |
L6182P |
probably damaging |
Het |
| Magi3 |
A |
T |
3: 103,992,662 (GRCm39) |
M270K |
probably benign |
Het |
| Mapre2 |
A |
T |
18: 23,886,888 (GRCm39) |
|
probably benign |
Het |
| Minar1 |
T |
A |
9: 89,483,234 (GRCm39) |
E721V |
probably damaging |
Het |
| Mllt10 |
T |
A |
2: 18,167,353 (GRCm39) |
V426D |
probably benign |
Het |
| Mrgprf |
A |
G |
7: 144,862,046 (GRCm39) |
I203V |
probably benign |
Het |
| Mrnip |
G |
A |
11: 50,067,688 (GRCm39) |
C27Y |
probably damaging |
Het |
| Mrpl24 |
C |
T |
3: 87,829,701 (GRCm39) |
R96* |
probably null |
Het |
| Nbas |
T |
A |
12: 13,402,875 (GRCm39) |
|
probably benign |
Het |
| Nipal4 |
G |
A |
11: 46,045,470 (GRCm39) |
T131M |
possibly damaging |
Het |
| Nlrp12 |
T |
C |
7: 3,289,621 (GRCm39) |
D297G |
possibly damaging |
Het |
| Nol6 |
A |
C |
4: 41,121,823 (GRCm39) |
M237R |
probably benign |
Het |
| Olig1 |
A |
G |
16: 91,067,027 (GRCm39) |
E88G |
probably benign |
Het |
| Or1j19 |
T |
A |
2: 36,676,855 (GRCm39) |
L106* |
probably null |
Het |
| Parg |
A |
G |
14: 31,931,175 (GRCm39) |
D265G |
possibly damaging |
Het |
| Pcdhgb8 |
A |
T |
18: 37,895,301 (GRCm39) |
I124L |
probably damaging |
Het |
| Pign |
A |
G |
1: 105,481,827 (GRCm39) |
F822L |
probably damaging |
Het |
| Plch2 |
T |
C |
4: 155,071,140 (GRCm39) |
T1080A |
probably benign |
Het |
| Pld4 |
A |
T |
12: 112,733,210 (GRCm39) |
Y262F |
possibly damaging |
Het |
| Ppp1r12b |
A |
G |
1: 134,693,730 (GRCm39) |
V977A |
probably benign |
Het |
| Ppp6r3 |
C |
T |
19: 3,521,984 (GRCm39) |
E565K |
|
Het |
| Psmg2 |
A |
G |
18: 67,787,158 (GRCm39) |
|
probably benign |
Het |
| Ptcd3 |
C |
T |
6: 71,885,645 (GRCm39) |
G27D |
probably benign |
Het |
| Retreg2 |
G |
T |
1: 75,119,525 (GRCm39) |
G7C |
unknown |
Het |
| Rlbp1 |
A |
T |
7: 79,027,114 (GRCm39) |
F182Y |
probably benign |
Het |
| Rnf148 |
G |
C |
6: 23,654,378 (GRCm39) |
S206C |
probably benign |
Het |
| Sash1 |
A |
G |
10: 8,637,869 (GRCm39) |
M1T |
probably null |
Het |
| Shank3 |
A |
T |
15: 89,433,598 (GRCm39) |
T1448S |
probably damaging |
Het |
| Slitrk6 |
A |
G |
14: 110,988,801 (GRCm39) |
I302T |
probably benign |
Het |
| Smc1b |
A |
G |
15: 84,950,529 (GRCm39) |
V1165A |
probably damaging |
Het |
| Sncaip |
A |
T |
18: 53,048,381 (GRCm39) |
H939L |
probably benign |
Het |
| Stn1 |
T |
C |
19: 47,524,709 (GRCm39) |
D27G |
probably damaging |
Het |
| Sugct |
T |
G |
13: 17,427,180 (GRCm39) |
|
probably null |
Het |
| Tmem259 |
A |
G |
10: 79,814,983 (GRCm39) |
S214P |
probably damaging |
Het |
| Trdv4 |
G |
A |
14: 54,312,946 (GRCm39) |
G107S |
probably damaging |
Het |
| Ttc3 |
C |
T |
16: 94,232,829 (GRCm39) |
L957F |
possibly damaging |
Het |
| Ttn |
A |
G |
2: 76,711,471 (GRCm39) |
Y8357H |
unknown |
Het |
| Twnk |
T |
C |
19: 44,996,434 (GRCm39) |
V289A |
probably benign |
Het |
| Umodl1 |
A |
G |
17: 31,202,958 (GRCm39) |
D437G |
possibly damaging |
Het |
| Upf1 |
T |
C |
8: 70,790,930 (GRCm39) |
T590A |
probably benign |
Het |
| Vmn2r63 |
A |
T |
7: 42,576,441 (GRCm39) |
D457E |
probably benign |
Het |
| Wdr82 |
A |
T |
9: 106,061,975 (GRCm39) |
T213S |
probably benign |
Het |
| Zfp267 |
T |
C |
3: 36,218,255 (GRCm39) |
Y93H |
possibly damaging |
Het |
| Zfp672 |
A |
T |
11: 58,220,590 (GRCm39) |
M3K |
unknown |
Het |
| Zfyve26 |
A |
G |
12: 79,285,742 (GRCm39) |
V2345A |
probably benign |
Het |
|
| Other mutations in Sipa1l1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01309:Sipa1l1
|
APN |
12 |
82,434,470 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01478:Sipa1l1
|
APN |
12 |
82,493,672 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01620:Sipa1l1
|
APN |
12 |
82,469,263 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02496:Sipa1l1
|
APN |
12 |
82,471,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02550:Sipa1l1
|
APN |
12 |
82,487,723 (GRCm39) |
nonsense |
probably null |
|
|
IGL02689:Sipa1l1
|
APN |
12 |
82,487,594 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02706:Sipa1l1
|
APN |
12 |
82,444,207 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02995:Sipa1l1
|
APN |
12 |
82,404,105 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL03104:Sipa1l1
|
APN |
12 |
82,388,904 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03295:Sipa1l1
|
APN |
12 |
82,479,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
bullae
|
UTSW |
12 |
82,389,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
bullish
|
UTSW |
12 |
82,469,245 (GRCm39) |
nonsense |
probably null |
|
|
ebullient
|
UTSW |
12 |
82,388,446 (GRCm39) |
missense |
probably benign |
0.18 |
|
PIT4431001:Sipa1l1
|
UTSW |
12 |
82,443,290 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0140:Sipa1l1
|
UTSW |
12 |
82,442,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0348:Sipa1l1
|
UTSW |
12 |
82,431,530 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0534:Sipa1l1
|
UTSW |
12 |
82,472,054 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0538:Sipa1l1
|
UTSW |
12 |
82,471,873 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0547:Sipa1l1
|
UTSW |
12 |
82,484,510 (GRCm39) |
missense |
probably benign |
|
|
R0980:Sipa1l1
|
UTSW |
12 |
82,388,994 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R1051:Sipa1l1
|
UTSW |
12 |
82,496,119 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1244:Sipa1l1
|
UTSW |
12 |
82,472,190 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1473:Sipa1l1
|
UTSW |
12 |
82,387,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1508:Sipa1l1
|
UTSW |
12 |
82,487,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1563:Sipa1l1
|
UTSW |
12 |
82,387,935 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1671:Sipa1l1
|
UTSW |
12 |
82,444,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Sipa1l1
|
UTSW |
12 |
82,419,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Sipa1l1
|
UTSW |
12 |
82,388,233 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2191:Sipa1l1
|
UTSW |
12 |
82,443,465 (GRCm39) |
nonsense |
probably null |
|
|
R2249:Sipa1l1
|
UTSW |
12 |
82,388,890 (GRCm39) |
missense |
probably benign |
|
|
R2909:Sipa1l1
|
UTSW |
12 |
82,404,105 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4012:Sipa1l1
|
UTSW |
12 |
82,388,556 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4154:Sipa1l1
|
UTSW |
12 |
82,471,988 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4382:Sipa1l1
|
UTSW |
12 |
82,493,596 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4448:Sipa1l1
|
UTSW |
12 |
82,388,524 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4651:Sipa1l1
|
UTSW |
12 |
82,469,245 (GRCm39) |
nonsense |
probably null |
|
|
R4652:Sipa1l1
|
UTSW |
12 |
82,469,245 (GRCm39) |
nonsense |
probably null |
|
|
R4751:Sipa1l1
|
UTSW |
12 |
82,387,968 (GRCm39) |
missense |
probably benign |
|
|
R4755:Sipa1l1
|
UTSW |
12 |
82,419,160 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4888:Sipa1l1
|
UTSW |
12 |
82,389,107 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4912:Sipa1l1
|
UTSW |
12 |
82,443,452 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4937:Sipa1l1
|
UTSW |
12 |
82,388,103 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5068:Sipa1l1
|
UTSW |
12 |
82,484,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5113:Sipa1l1
|
UTSW |
12 |
82,487,682 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5114:Sipa1l1
|
UTSW |
12 |
82,487,682 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5240:Sipa1l1
|
UTSW |
12 |
82,388,362 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6041:Sipa1l1
|
UTSW |
12 |
82,389,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Sipa1l1
|
UTSW |
12 |
82,487,643 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6170:Sipa1l1
|
UTSW |
12 |
82,388,446 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6185:Sipa1l1
|
UTSW |
12 |
82,471,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6326:Sipa1l1
|
UTSW |
12 |
82,419,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6842:Sipa1l1
|
UTSW |
12 |
82,467,320 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7008:Sipa1l1
|
UTSW |
12 |
82,409,886 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7058:Sipa1l1
|
UTSW |
12 |
82,449,896 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7069:Sipa1l1
|
UTSW |
12 |
82,388,180 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7122:Sipa1l1
|
UTSW |
12 |
82,469,236 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7310:Sipa1l1
|
UTSW |
12 |
82,419,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7469:Sipa1l1
|
UTSW |
12 |
82,467,438 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7718:Sipa1l1
|
UTSW |
12 |
82,389,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7787:Sipa1l1
|
UTSW |
12 |
82,496,762 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7844:Sipa1l1
|
UTSW |
12 |
82,444,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7893:Sipa1l1
|
UTSW |
12 |
82,388,342 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7953:Sipa1l1
|
UTSW |
12 |
82,496,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8043:Sipa1l1
|
UTSW |
12 |
82,496,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8099:Sipa1l1
|
UTSW |
12 |
82,480,600 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8135:Sipa1l1
|
UTSW |
12 |
82,388,075 (GRCm39) |
missense |
probably benign |
|
|
R8229:Sipa1l1
|
UTSW |
12 |
82,484,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8348:Sipa1l1
|
UTSW |
12 |
82,443,045 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8388:Sipa1l1
|
UTSW |
12 |
82,216,259 (GRCm39) |
unclassified |
probably benign |
|
|
R8693:Sipa1l1
|
UTSW |
12 |
82,216,517 (GRCm39) |
unclassified |
probably benign |
|
|
R8884:Sipa1l1
|
UTSW |
12 |
82,409,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8940:Sipa1l1
|
UTSW |
12 |
82,404,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8975:Sipa1l1
|
UTSW |
12 |
82,479,612 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9145:Sipa1l1
|
UTSW |
12 |
82,443,335 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9328:Sipa1l1
|
UTSW |
12 |
82,388,792 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9455:Sipa1l1
|
UTSW |
12 |
82,434,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9486:Sipa1l1
|
UTSW |
12 |
82,404,139 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9631:Sipa1l1
|
UTSW |
12 |
82,387,776 (GRCm39) |
start codon destroyed |
probably null |
0.39 |
|
R9727:Sipa1l1
|
UTSW |
12 |
82,471,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Sipa1l1
|
UTSW |
12 |
82,463,763 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACAAGAGCAATGAACTCGTCATG -3'
(R):5'- ATTCACAGGCATCTCAGGTCAC -3'
Sequencing Primer
(F):5'- GCAATGAACTCGTCATGAGCTGTC -3'
(R):5'- TCTCAGGTCACCGCTAAAAC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation