Incidental Mutation 'R8830:Mical2'
| ID |
673750 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.298)
|
| Stock # |
R8830 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 111980403 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 126
(T126A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000062443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033033]
[ENSMUST00000051308]
[ENSMUST00000106645]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000033033
AA Change: T192A
PolyPhen 2
Score 0.048 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000033033
Gene: ENSMUSG00000030771
AA Change: T192A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
393 |
404 |
N/A |
INTRINSIC |
|
low complexity region
|
415 |
432 |
N/A |
INTRINSIC |
|
low complexity region
|
545 |
562 |
N/A |
INTRINSIC |
|
coiled coil region
|
569 |
597 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000051308
AA Change: T126A
PolyPhen 2
Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000062443
Gene: ENSMUSG00000030771
AA Change: T126A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106645
AA Change: T126A
PolyPhen 2
Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000102256
Gene: ENSMUSG00000030771
AA Change: T126A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
low complexity region
|
349 |
366 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
DUF3585
|
526 |
668 |
6.86e-56 |
SMART |
|
| Predicted Effect |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000215412
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.7%
|
| Validation Efficiency |
100% (68/68) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2fm2 |
A |
T |
3: 59,654,744 (GRCm39) |
T193S |
probably benign |
Het |
| Abca7 |
T |
A |
10: 79,844,805 (GRCm39) |
V1509E |
probably damaging |
Het |
| Abraxas2 |
A |
G |
7: 132,485,085 (GRCm39) |
D376G |
probably damaging |
Het |
| Agbl1 |
A |
G |
7: 75,985,059 (GRCm39) |
T159A |
|
Het |
| Ahnak2 |
G |
A |
12: 112,750,656 (GRCm39) |
R89W |
|
Het |
| Ajm1 |
T |
G |
2: 25,467,262 (GRCm39) |
D883A |
|
Het |
| Arhgef40 |
A |
C |
14: 52,241,165 (GRCm39) |
D1396A |
probably damaging |
Het |
| Atp13a5 |
A |
T |
16: 29,066,928 (GRCm39) |
F1060I |
probably damaging |
Het |
| Atp6v1c1 |
T |
A |
15: 38,677,789 (GRCm39) |
F105I |
probably damaging |
Het |
| Atp9b |
C |
T |
18: 80,809,015 (GRCm39) |
E635K |
|
Het |
| Brix1 |
T |
A |
15: 10,479,682 (GRCm39) |
Q124L |
possibly damaging |
Het |
| Cep68 |
A |
G |
11: 20,180,418 (GRCm39) |
|
probably benign |
Het |
| Cfap46 |
A |
G |
7: 139,195,565 (GRCm39) |
S2208P |
unknown |
Het |
| Crisp1 |
T |
A |
17: 40,605,310 (GRCm39) |
K234* |
probably null |
Het |
| Cryzl1 |
C |
T |
16: 91,509,092 (GRCm39) |
V70I |
probably benign |
Het |
| Cybc1 |
C |
T |
11: 121,119,549 (GRCm39) |
|
probably benign |
Het |
| Dnah7b |
T |
C |
1: 46,230,953 (GRCm39) |
Y1404H |
probably damaging |
Het |
| Dot1l |
A |
G |
10: 80,607,033 (GRCm39) |
H109R |
possibly damaging |
Het |
| E330034G19Rik |
A |
C |
14: 24,359,576 (GRCm39) |
H329P |
unknown |
Het |
| Erbb4 |
A |
T |
1: 68,114,627 (GRCm39) |
L939Q |
probably damaging |
Het |
| Fst |
A |
T |
13: 114,592,364 (GRCm39) |
C118S |
probably damaging |
Het |
| Gfra3 |
A |
G |
18: 34,844,189 (GRCm39) |
V117A |
possibly damaging |
Het |
| Gldc |
C |
G |
19: 30,078,212 (GRCm39) |
M928I |
probably benign |
Het |
| Greb1 |
A |
G |
12: 16,738,520 (GRCm39) |
M1481T |
probably benign |
Het |
| Hecw2 |
G |
A |
1: 53,930,305 (GRCm39) |
R1045C |
probably damaging |
Het |
| Hexb |
C |
T |
13: 97,330,762 (GRCm39) |
V84I |
probably benign |
Het |
| Hpse |
T |
C |
5: 100,843,452 (GRCm39) |
E240G |
probably benign |
Het |
| Hspa12a |
T |
C |
19: 58,793,895 (GRCm39) |
D322G |
possibly damaging |
Het |
| Hspa9 |
A |
T |
18: 35,081,157 (GRCm39) |
|
probably null |
Het |
| Kif9 |
A |
G |
9: 110,353,998 (GRCm39) |
K790R |
probably damaging |
Het |
| Klc2 |
C |
T |
19: 5,160,394 (GRCm39) |
|
probably null |
Het |
| Ldha |
C |
G |
7: 46,499,702 (GRCm39) |
N144K |
probably benign |
Het |
| Mrpl15 |
A |
T |
1: 4,852,807 (GRCm39) |
V137D |
probably damaging |
Het |
| Muc16 |
G |
A |
9: 18,557,365 (GRCm39) |
T2976I |
unknown |
Het |
| Mybpc2 |
A |
T |
7: 44,161,965 (GRCm39) |
V495D |
probably damaging |
Het |
| Or10a5 |
A |
G |
7: 106,635,889 (GRCm39) |
N176D |
probably benign |
Het |
| Or52ab2 |
A |
G |
7: 102,970,212 (GRCm39) |
K198R |
|
Het |
| Or6c203 |
A |
T |
10: 129,010,715 (GRCm39) |
Y58* |
probably null |
Het |
| Pcnt |
G |
A |
10: 76,218,008 (GRCm39) |
T2089I |
probably benign |
Het |
| Pdzd7 |
T |
C |
19: 45,021,512 (GRCm39) |
D563G |
probably damaging |
Het |
| Phlpp1 |
T |
G |
1: 106,278,333 (GRCm39) |
L915R |
probably damaging |
Het |
| Plekhh2 |
T |
A |
17: 84,829,231 (GRCm39) |
I34N |
probably damaging |
Het |
| Pou6f2 |
T |
A |
13: 18,553,083 (GRCm39) |
T84S |
|
Het |
| Prxl2c |
G |
A |
13: 64,445,114 (GRCm39) |
Q170* |
probably null |
Het |
| Ptprq |
A |
G |
10: 107,422,556 (GRCm39) |
V1612A |
possibly damaging |
Het |
| Pvrig-ps |
T |
G |
5: 138,340,410 (GRCm39) |
|
probably benign |
Het |
| Rasl10b |
A |
T |
11: 83,303,502 (GRCm39) |
I20F |
probably damaging |
Het |
| Rimbp3 |
T |
A |
16: 17,026,870 (GRCm39) |
V98E |
probably damaging |
Het |
| Rims2 |
T |
C |
15: 39,300,758 (GRCm39) |
I355T |
possibly damaging |
Het |
| Slc1a2 |
A |
G |
2: 102,566,360 (GRCm39) |
H30R |
probably benign |
Het |
| Slc28a1 |
G |
A |
7: 80,810,794 (GRCm39) |
V389M |
possibly damaging |
Het |
| Slc7a13 |
T |
C |
4: 19,819,189 (GRCm39) |
S130P |
probably benign |
Het |
| Sp140 |
TTTTTTTT |
TTTTTTTTTTTTT |
1: 85,572,295 (GRCm39) |
|
probably benign |
Het |
| Spag17 |
T |
A |
3: 100,032,751 (GRCm39) |
H2320Q |
possibly damaging |
Het |
| Speer4a1 |
T |
C |
5: 26,241,793 (GRCm39) |
E111G |
possibly damaging |
Het |
| Ss18l1 |
T |
C |
2: 179,709,131 (GRCm39) |
Y397H |
unknown |
Het |
| Tbck |
T |
C |
3: 132,543,818 (GRCm39) |
S890P |
probably damaging |
Het |
| Tcp11 |
T |
C |
17: 28,299,204 (GRCm39) |
E17G |
probably benign |
Het |
| Tesk2 |
C |
T |
4: 116,659,484 (GRCm39) |
R315C |
probably benign |
Het |
| Tln1 |
T |
C |
4: 43,556,383 (GRCm39) |
N45S |
probably benign |
Het |
| Trim10 |
C |
T |
17: 37,180,846 (GRCm39) |
P26S |
probably damaging |
Het |
| Vmac |
C |
A |
17: 57,022,573 (GRCm39) |
G146C |
probably damaging |
Het |
| Vmn1r14 |
G |
A |
6: 57,211,017 (GRCm39) |
M198I |
probably damaging |
Het |
| Vmn1r194 |
T |
C |
13: 22,429,006 (GRCm39) |
Y208H |
possibly damaging |
Het |
| Vmn1r78 |
G |
A |
7: 11,887,118 (GRCm39) |
C243Y |
probably damaging |
Het |
| Wasf3 |
C |
T |
5: 146,403,672 (GRCm39) |
Q261* |
probably null |
Het |
| Ybx2 |
A |
G |
11: 69,827,063 (GRCm39) |
K88R |
probably benign |
Het |
| Zfhx4 |
G |
A |
3: 5,463,949 (GRCm39) |
R1394H |
probably damaging |
Het |
| Zfp871 |
T |
C |
17: 32,993,901 (GRCm39) |
T425A |
probably benign |
Het |
| Zfy2 |
C |
T |
Y: 2,106,600 (GRCm39) |
S678N |
possibly damaging |
Het |
| Zswim4 |
T |
C |
8: 84,949,945 (GRCm39) |
E650G |
possibly damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCAATCTACCTCAGACGTGC -3'
(R):5'- GTGCAGTCACTCCAGTCTAG -3'
Sequencing Primer
(F):5'- CCAGGGCTCAAGGGATTGTG -3'
(R):5'- AGTCACTCCAGTCTAGCAACTTG -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation