Incidental Mutation 'R8831:Atrn'
| ID |
673804 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| MMRRC Submission |
068659-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8831 (G1)
|
| Quality Score |
154.008 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
130748415-130872253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 130748521 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 14
(L14P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
[ENSMUST00000146975]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028781
AA Change: L14P
PolyPhen 2
Score 0.216 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: L14P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146975
|
| Meta Mutation Damage Score |
0.1115 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
99% (81/82) |
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A230072I06Rik |
A |
T |
8: 12,329,688 (GRCm39) |
I48L |
unknown |
Het |
| Abcc3 |
A |
C |
11: 94,241,787 (GRCm39) |
C1415G |
probably damaging |
Het |
| Abcf3 |
C |
T |
16: 20,369,214 (GRCm39) |
R205C |
probably damaging |
Het |
| Abcg5 |
G |
T |
17: 84,976,423 (GRCm39) |
H471Q |
probably damaging |
Het |
| Actl6b |
G |
A |
5: 137,565,305 (GRCm39) |
R363Q |
probably damaging |
Het |
| Adcy1 |
T |
A |
11: 7,111,362 (GRCm39) |
D884E |
probably benign |
Het |
| Aldh3a1 |
A |
G |
11: 61,107,142 (GRCm39) |
Y282C |
probably damaging |
Het |
| Amdhd2 |
A |
G |
17: 24,376,712 (GRCm39) |
|
probably null |
Het |
| Arfgef3 |
A |
G |
10: 18,528,491 (GRCm39) |
S299P |
possibly damaging |
Het |
| Asic2 |
A |
T |
11: 81,858,726 (GRCm39) |
N95K |
probably damaging |
Het |
| Atp2c2 |
A |
G |
8: 120,476,033 (GRCm39) |
|
probably null |
Het |
| C8b |
A |
G |
4: 104,647,874 (GRCm39) |
Y355C |
probably damaging |
Het |
| Carm1 |
A |
G |
9: 21,491,663 (GRCm39) |
E244G |
probably damaging |
Het |
| Cd300c2 |
A |
T |
11: 114,891,844 (GRCm39) |
C39* |
probably null |
Het |
| Cish |
T |
A |
9: 107,177,671 (GRCm39) |
F116I |
probably damaging |
Het |
| Clstn1 |
G |
A |
4: 149,730,780 (GRCm39) |
R837Q |
probably benign |
Het |
| Cox10 |
A |
G |
11: 63,855,306 (GRCm39) |
F325S |
probably damaging |
Het |
| Cplane1 |
T |
C |
15: 8,211,620 (GRCm39) |
I320T |
probably benign |
Het |
| Ctps1 |
A |
T |
4: 120,424,507 (GRCm39) |
S36T |
possibly damaging |
Het |
| Dchs2 |
T |
C |
3: 83,192,670 (GRCm39) |
L1705P |
probably benign |
Het |
| Defb25 |
C |
A |
2: 152,464,899 (GRCm39) |
V17L |
probably benign |
Het |
| Dhx16 |
A |
G |
17: 36,199,000 (GRCm39) |
D782G |
probably damaging |
Het |
| Dhx30 |
A |
G |
9: 109,917,319 (GRCm39) |
S399P |
probably benign |
Het |
| Dhx58 |
T |
A |
11: 100,594,806 (GRCm39) |
K30M |
probably damaging |
Het |
| Drc7 |
G |
A |
8: 95,788,845 (GRCm39) |
R301Q |
probably damaging |
Het |
| Dsg1a |
T |
C |
18: 20,453,365 (GRCm39) |
V21A |
probably damaging |
Het |
| Ercc6 |
T |
A |
14: 32,282,784 (GRCm39) |
|
probably null |
Het |
| Fam193a |
A |
G |
5: 34,616,374 (GRCm39) |
T850A |
probably benign |
Het |
| Fgf10 |
A |
G |
13: 118,925,671 (GRCm39) |
D150G |
probably damaging |
Het |
| Flii |
A |
T |
11: 60,616,074 (GRCm39) |
N28K |
probably benign |
Het |
| Gfi1 |
G |
A |
5: 107,868,138 (GRCm39) |
R377C |
probably damaging |
Het |
| Gfra2 |
A |
T |
14: 71,204,503 (GRCm39) |
N324I |
probably benign |
Het |
| Gm10308 |
A |
G |
17: 91,396,431 (GRCm39) |
R118G |
unknown |
Het |
| Gm10801 |
T |
A |
2: 98,494,334 (GRCm39) |
V137E |
probably damaging |
Het |
| Hmmr |
G |
A |
11: 40,612,499 (GRCm39) |
S206F |
probably damaging |
Het |
| Hsd3b9 |
A |
T |
3: 98,354,047 (GRCm39) |
W151R |
probably benign |
Het |
| Ift80 |
G |
A |
3: 68,869,583 (GRCm39) |
A236V |
probably damaging |
Het |
| Il1rn |
A |
T |
2: 24,239,505 (GRCm39) |
T134S |
possibly damaging |
Het |
| Il6st |
G |
T |
13: 112,640,914 (GRCm39) |
D897Y |
probably damaging |
Het |
| Imp4 |
T |
C |
1: 34,483,445 (GRCm39) |
M257T |
probably benign |
Het |
| Impdh2 |
T |
C |
9: 108,441,957 (GRCm39) |
L377S |
probably damaging |
Het |
| Kdm1b |
C |
A |
13: 47,217,617 (GRCm39) |
L359I |
possibly damaging |
Het |
| Kidins220 |
A |
T |
12: 25,086,454 (GRCm39) |
I963L |
possibly damaging |
Het |
| Mdm4 |
T |
C |
1: 132,931,601 (GRCm39) |
R148G |
probably benign |
Het |
| Myl10 |
G |
C |
5: 136,726,825 (GRCm39) |
V70L |
probably benign |
Het |
| Ncor1 |
A |
T |
11: 62,260,234 (GRCm39) |
D505E |
probably benign |
Het |
| Necab3 |
A |
T |
2: 154,396,607 (GRCm39) |
L107Q |
probably damaging |
Het |
| Nkx2-4 |
G |
A |
2: 146,927,114 (GRCm39) |
P51L |
probably benign |
Het |
| Nol11 |
T |
C |
11: 107,067,662 (GRCm39) |
T388A |
probably benign |
Het |
| Npc1 |
T |
A |
18: 12,333,877 (GRCm39) |
M735L |
probably benign |
Het |
| Nr1h3 |
C |
A |
2: 91,021,091 (GRCm39) |
R232L |
probably benign |
Het |
| Nrcam |
T |
A |
12: 44,591,680 (GRCm39) |
|
probably null |
Het |
| Or1j13 |
G |
A |
2: 36,369,794 (GRCm39) |
T116I |
possibly damaging |
Het |
| Or52s1b |
T |
A |
7: 102,822,203 (GRCm39) |
I214L |
probably benign |
Het |
| Pabpn1 |
T |
C |
14: 55,131,914 (GRCm39) |
V101A |
probably damaging |
Het |
| Pcare |
A |
T |
17: 72,059,305 (GRCm39) |
V124E |
probably benign |
Het |
| Pcbp2 |
A |
G |
15: 102,394,453 (GRCm39) |
D217G |
probably benign |
Het |
| Pcdhb12 |
A |
G |
18: 37,570,386 (GRCm39) |
M511V |
probably benign |
Het |
| Phf3 |
T |
A |
1: 30,860,347 (GRCm39) |
K828* |
probably null |
Het |
| Plcg1 |
G |
C |
2: 160,589,732 (GRCm39) |
K85N |
probably benign |
Het |
| Prag1 |
A |
T |
8: 36,613,891 (GRCm39) |
T1148S |
probably benign |
Het |
| Prmt3 |
A |
G |
7: 49,478,729 (GRCm39) |
E430G |
probably null |
Het |
| Prx |
G |
T |
7: 27,217,538 (GRCm39) |
V819F |
probably damaging |
Het |
| Ptpn18 |
A |
T |
1: 34,511,271 (GRCm39) |
R338W |
probably null |
Het |
| Rab6a |
T |
C |
7: 100,283,931 (GRCm39) |
Y128H |
probably benign |
Het |
| Rgs2 |
T |
C |
1: 143,877,497 (GRCm39) |
Y186C |
probably damaging |
Het |
| Rhbdl1 |
C |
T |
17: 26,053,857 (GRCm39) |
V342M |
probably damaging |
Het |
| Rpn1 |
A |
G |
6: 88,061,775 (GRCm39) |
Q88R |
probably benign |
Het |
| Slc19a2 |
C |
T |
1: 164,084,443 (GRCm39) |
T111M |
probably damaging |
Het |
| Slc35e4 |
G |
A |
11: 3,863,087 (GRCm39) |
P34L |
possibly damaging |
Het |
| Slc7a6os |
A |
T |
8: 106,937,189 (GRCm39) |
D90E |
probably benign |
Het |
| Ssh3 |
A |
G |
19: 4,319,053 (GRCm39) |
V19A |
possibly damaging |
Het |
| Susd1 |
C |
T |
4: 59,379,594 (GRCm39) |
|
probably benign |
Het |
| Tcf19 |
A |
T |
17: 35,825,794 (GRCm39) |
M121K |
possibly damaging |
Het |
| Tcp11 |
G |
A |
17: 28,299,193 (GRCm39) |
R21C |
probably damaging |
Het |
| Tcp11l2 |
A |
G |
10: 84,449,522 (GRCm39) |
I496V |
probably damaging |
Het |
| Tenm3 |
C |
T |
8: 48,729,417 (GRCm39) |
A1530T |
|
Het |
| Tmem127 |
T |
A |
2: 127,098,979 (GRCm39) |
V171D |
probably damaging |
Het |
| Tyrp1 |
G |
A |
4: 80,753,399 (GRCm39) |
C30Y |
probably damaging |
Het |
| Usp48 |
A |
T |
4: 137,341,080 (GRCm39) |
D360V |
probably damaging |
Het |
| Vamp4 |
T |
A |
1: 162,401,952 (GRCm39) |
D11E |
possibly damaging |
Het |
| Vmn1r14 |
T |
C |
6: 57,210,505 (GRCm39) |
F28L |
probably benign |
Het |
| Vmn2r69 |
G |
T |
7: 85,059,018 (GRCm39) |
C514* |
probably null |
Het |
| Vmn2r84 |
G |
A |
10: 130,226,968 (GRCm39) |
A290V |
probably benign |
Het |
| Zfp1007 |
A |
T |
5: 109,824,174 (GRCm39) |
S425R |
probably benign |
Het |
| Zhx3 |
T |
A |
2: 160,622,691 (GRCm39) |
Y492F |
probably benign |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,799,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,836,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,789,556 (GRCm39) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
130,844,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,777,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,800,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
130,844,674 (GRCm39) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
130,862,897 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,814,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,789,654 (GRCm39) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,812,064 (GRCm39) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,799,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0403:Atrn
|
UTSW |
2 |
130,748,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,841,085 (GRCm39) |
nonsense |
probably null |
|
|
R0544:Atrn
|
UTSW |
2 |
130,828,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0570:Atrn
|
UTSW |
2 |
130,822,054 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0606:Atrn
|
UTSW |
2 |
130,748,776 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0617:Atrn
|
UTSW |
2 |
130,837,005 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,841,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
130,862,927 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,799,000 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,777,544 (GRCm39) |
missense |
probably benign |
|
|
R1795:Atrn
|
UTSW |
2 |
130,814,208 (GRCm39) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,824,692 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1921:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,799,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,812,142 (GRCm39) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,777,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,799,916 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,799,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,803,595 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
130,862,876 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,836,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,806,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,836,148 (GRCm39) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,775,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,812,128 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,802,388 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,815,424 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,823,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,775,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
130,862,910 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,836,967 (GRCm39) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,817,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,836,113 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,812,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R5256:Atrn
|
UTSW |
2 |
130,787,939 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5494:Atrn
|
UTSW |
2 |
130,864,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,811,936 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,748,464 (GRCm39) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,775,356 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
130,862,900 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,788,011 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,821,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
130,864,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,828,664 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,789,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,803,491 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,822,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,806,807 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,812,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,777,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
130,855,561 (GRCm39) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,817,908 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,802,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
130,864,920 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,777,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,846,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,748,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8937:Atrn
|
UTSW |
2 |
130,841,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,777,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,803,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,786,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF009:Atrn
|
UTSW |
2 |
130,748,842 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0024:Atrn
|
UTSW |
2 |
130,800,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,815,319 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,788,113 (GRCm39) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,787,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTAAGACCCTGGCATTGAG -3'
(R):5'- TCTACCCTCGCGATTTCAAG -3'
Sequencing Primer
(F):5'- AGGTCTACATGCTGGGCAC -3'
(R):5'- GCGATTTCAAGCCCTGCAC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation