Incidental Mutation 'R8855:Dennd4a'
| ID |
675255 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
068736-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.489)
|
| Stock # |
R8855 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
64718622-64826949 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 64819672 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 1761
(G1761D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000038890
AA Change: G1761D
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: G1761D
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2 |
C |
T |
3: 59,914,511 (GRCm39) |
T38I |
probably benign |
Het |
| Ace |
T |
A |
11: 105,861,424 (GRCm39) |
L191* |
probably null |
Het |
| Ahctf1 |
G |
A |
1: 179,614,341 (GRCm39) |
H451Y |
probably damaging |
Het |
| Amotl1 |
C |
A |
9: 14,466,869 (GRCm39) |
|
probably null |
Het |
| Angptl6 |
T |
A |
9: 20,786,940 (GRCm39) |
Y261F |
probably damaging |
Het |
| Arhgap1 |
G |
T |
2: 91,499,744 (GRCm39) |
S293I |
probably benign |
Het |
| Atg9a |
A |
C |
1: 75,161,867 (GRCm39) |
F560V |
probably damaging |
Het |
| B4galnt4 |
G |
A |
7: 140,648,488 (GRCm39) |
G668D |
possibly damaging |
Het |
| Btaf1 |
T |
A |
19: 36,935,901 (GRCm39) |
N230K |
probably benign |
Het |
| Ccne1 |
A |
C |
7: 37,800,046 (GRCm39) |
H179Q |
probably benign |
Het |
| Cdk5rap2 |
A |
T |
4: 70,218,887 (GRCm39) |
D623E |
probably damaging |
Het |
| Cenpf |
C |
A |
1: 189,385,430 (GRCm39) |
K2283N |
probably benign |
Het |
| Clec16a |
A |
T |
16: 10,462,731 (GRCm39) |
D683V |
probably damaging |
Het |
| Clvs2 |
T |
C |
10: 33,404,400 (GRCm39) |
D272G |
probably benign |
Het |
| Cnksr1 |
A |
G |
4: 133,959,494 (GRCm39) |
V380A |
probably damaging |
Het |
| Col20a1 |
C |
A |
2: 180,655,684 (GRCm39) |
P42T |
|
Het |
| Ddx47 |
A |
G |
6: 135,000,356 (GRCm39) |
K451E |
probably benign |
Het |
| Dnah11 |
T |
A |
12: 118,156,107 (GRCm39) |
H181L |
probably benign |
Het |
| Dync1h1 |
T |
C |
12: 110,602,333 (GRCm39) |
C2074R |
probably damaging |
Het |
| Ell2 |
A |
T |
13: 75,917,793 (GRCm39) |
Q574H |
probably damaging |
Het |
| Enpp7 |
A |
G |
11: 118,879,191 (GRCm39) |
N50S |
possibly damaging |
Het |
| Fbp2 |
T |
C |
13: 62,989,709 (GRCm39) |
K199R |
probably benign |
Het |
| Fetub |
A |
T |
16: 22,758,321 (GRCm39) |
E368V |
possibly damaging |
Het |
| Flt1 |
A |
T |
5: 147,507,682 (GRCm39) |
D1209E |
probably benign |
Het |
| Flt1 |
A |
T |
5: 147,618,460 (GRCm39) |
N260K |
probably damaging |
Het |
| Fras1 |
A |
G |
5: 96,917,465 (GRCm39) |
H3495R |
|
Het |
| Fsip2 |
A |
G |
2: 82,810,521 (GRCm39) |
Q2280R |
probably benign |
Het |
| Gja10 |
A |
T |
4: 32,601,573 (GRCm39) |
C270* |
probably null |
Het |
| Gpld1 |
A |
G |
13: 25,170,890 (GRCm39) |
T794A |
probably benign |
Het |
| Gsk3b |
A |
G |
16: 38,004,900 (GRCm39) |
Y157C |
probably damaging |
Het |
| Gsta2 |
T |
C |
9: 78,244,880 (GRCm39) |
K78R |
probably damaging |
Het |
| Gtf3a |
A |
G |
5: 146,885,721 (GRCm39) |
D44G |
probably benign |
Het |
| Hap1 |
C |
A |
11: 100,246,864 (GRCm39) |
G14W |
probably damaging |
Het |
| Hcn4 |
T |
A |
9: 58,765,387 (GRCm39) |
I623N |
unknown |
Het |
| Kank1 |
T |
C |
19: 25,388,702 (GRCm39) |
S792P |
possibly damaging |
Het |
| Klra5 |
A |
T |
6: 129,880,533 (GRCm39) |
W212R |
probably damaging |
Het |
| Kmt2d |
A |
T |
15: 98,754,237 (GRCm39) |
L1622Q |
unknown |
Het |
| Lipi |
T |
A |
16: 75,355,481 (GRCm39) |
D343V |
probably damaging |
Het |
| Lrp6 |
A |
T |
6: 134,445,785 (GRCm39) |
N1009K |
probably benign |
Het |
| Lrrc39 |
T |
A |
3: 116,363,790 (GRCm39) |
I121N |
probably damaging |
Het |
| Mamstr |
A |
T |
7: 45,294,403 (GRCm39) |
D419V |
probably benign |
Het |
| Map2k7 |
C |
T |
8: 4,293,594 (GRCm39) |
T119I |
probably damaging |
Het |
| Mov10l1 |
A |
T |
15: 88,896,169 (GRCm39) |
D671V |
probably benign |
Het |
| Mrps24 |
A |
T |
11: 5,654,642 (GRCm39) |
L104Q |
probably damaging |
Het |
| Myh1 |
T |
A |
11: 67,102,247 (GRCm39) |
L846H |
probably damaging |
Het |
| Ndufaf5 |
T |
A |
2: 140,025,840 (GRCm39) |
I133N |
possibly damaging |
Het |
| Ndufs5 |
A |
G |
4: 123,609,655 (GRCm39) |
|
probably null |
Het |
| Numa1 |
G |
C |
7: 101,639,835 (GRCm39) |
D62H |
possibly damaging |
Het |
| Or10g3 |
A |
T |
14: 52,610,196 (GRCm39) |
Y105N |
probably damaging |
Het |
| Or52e19 |
T |
A |
7: 102,959,168 (GRCm39) |
I80N |
probably damaging |
Het |
| Or52p2 |
G |
T |
7: 102,237,945 (GRCm39) |
Q2K |
probably benign |
Het |
| Or8b12c |
C |
G |
9: 37,715,709 (GRCm39) |
F167L |
probably damaging |
Het |
| Pag1 |
T |
C |
3: 9,764,529 (GRCm39) |
K208R |
probably benign |
Het |
| Pkd1 |
T |
C |
17: 24,792,051 (GRCm39) |
V1246A |
probably damaging |
Het |
| Plekhg2 |
T |
C |
7: 28,069,526 (GRCm39) |
T144A |
probably benign |
Het |
| Plekhm2 |
A |
T |
4: 141,361,658 (GRCm39) |
S262T |
probably benign |
Het |
| Pramel14 |
A |
T |
4: 143,720,905 (GRCm39) |
L12Q |
probably damaging |
Het |
| Prpf4 |
A |
G |
4: 62,334,235 (GRCm39) |
D230G |
probably benign |
Het |
| Rbm15b |
C |
T |
9: 106,763,595 (GRCm39) |
R191Q |
probably benign |
Het |
| Sec16a |
G |
A |
2: 26,329,852 (GRCm39) |
T721I |
probably benign |
Het |
| Serpinb6c |
A |
T |
13: 34,083,309 (GRCm39) |
I35N |
probably damaging |
Het |
| Sgk1 |
T |
G |
10: 21,871,726 (GRCm39) |
S181A |
probably benign |
Het |
| Slc25a10 |
T |
C |
11: 120,385,795 (GRCm39) |
S74P |
probably damaging |
Het |
| Slc30a3 |
C |
A |
5: 31,245,325 (GRCm39) |
V332F |
possibly damaging |
Het |
| Smg1 |
A |
G |
7: 117,806,122 (GRCm39) |
S240P |
unknown |
Het |
| Snapc4 |
G |
A |
2: 26,264,545 (GRCm39) |
R265W |
probably damaging |
Het |
| Taar1 |
C |
T |
10: 23,796,976 (GRCm39) |
R225C |
possibly damaging |
Het |
| Tmem74 |
A |
G |
15: 43,730,231 (GRCm39) |
S271P |
probably damaging |
Het |
| Trank1 |
T |
C |
9: 111,141,289 (GRCm39) |
V127A |
unknown |
Het |
| Trim66 |
G |
T |
7: 109,081,188 (GRCm39) |
H244N |
probably damaging |
Het |
| Tshz2 |
T |
A |
2: 169,728,425 (GRCm39) |
L1007H |
probably damaging |
Het |
| Ttc39c |
A |
T |
18: 12,831,003 (GRCm39) |
S288C |
probably benign |
Het |
| Twnk |
C |
T |
19: 45,000,272 (GRCm39) |
Q663* |
probably null |
Het |
| Ucn |
T |
A |
5: 31,295,857 (GRCm39) |
Q3L |
probably benign |
Het |
| Usp9y |
C |
T |
Y: 1,395,758 (GRCm39) |
R492H |
probably damaging |
Het |
| Vars1 |
T |
C |
17: 35,234,620 (GRCm39) |
S1150P |
probably benign |
Het |
| Zc3h7b |
G |
A |
15: 81,656,681 (GRCm39) |
R166Q |
probably benign |
Het |
| Zfand1 |
T |
C |
3: 10,405,811 (GRCm39) |
D264G |
probably benign |
Het |
| Zfp839 |
A |
G |
12: 110,834,848 (GRCm39) |
E701G |
probably benign |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,819,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,814,166 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,749,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,801,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,816,988 (GRCm39) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,758,580 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,769,609 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,817,473 (GRCm39) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,804,635 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,769,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,779,156 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,795,808 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,796,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,779,164 (GRCm39) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,803,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,803,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,800,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,759,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,769,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,758,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,818,957 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,817,286 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,813,327 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,818,947 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,779,164 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,796,887 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,766,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,769,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,804,516 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,804,618 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,796,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,749,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,759,749 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,759,749 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,796,887 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,813,256 (GRCm39) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,796,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,759,699 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,813,363 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,819,669 (GRCm39) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,779,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,759,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,769,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,819,174 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,801,689 (GRCm39) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,804,639 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,804,531 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,796,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,803,872 (GRCm39) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,746,126 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,813,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,796,210 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,811,509 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,758,491 (GRCm39) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,804,011 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,819,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,794,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,779,181 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,759,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,794,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,759,771 (GRCm39) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,814,205 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,801,681 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,803,756 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,769,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,804,551 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,759,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,780,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,795,869 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,759,713 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,814,202 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,780,275 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,759,794 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,780,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,795,850 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,756,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,814,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,796,391 (GRCm39) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,746,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,794,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9219:Dennd4a
|
UTSW |
9 |
64,796,376 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,749,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,819,974 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,814,388 (GRCm39) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,800,640 (GRCm39) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,801,793 (GRCm39) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,804,602 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,779,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGCCACAAAACTCTGCAGG -3'
(R):5'- TGCTTCTCATGGGCTATAACC -3'
Sequencing Primer
(F):5'- CAAAACTCTGCAGGCCTATTTC -3'
(R):5'- GGCTATAACCCATCATCTGAGGG -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation