Incidental Mutation 'R8867:Lrrc7'
| ID |
675991 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrrc7
|
| Ensembl Gene |
ENSMUSG00000028176 |
| Gene Name |
leucine rich repeat containing 7 |
| Synonyms |
densin |
| MMRRC Submission |
068682-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.748)
|
| Stock # |
R8867 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
157788528-158267858 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 157867521 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 740
(D740V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142498
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106044]
[ENSMUST00000199890]
[ENSMUST00000200137]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000106044
AA Change: D740V
PolyPhen 2
Score 0.628 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000101659
Gene: ENSMUSG00000028176
AA Change: D740V
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1349 |
1378 |
2e-11 |
BLAST |
|
PDZ
|
1460 |
1540 |
1.33e-19 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000199890
AA Change: D740V
PolyPhen 2
Score 0.628 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000142440
Gene: ENSMUSG00000028176
AA Change: D740V
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
9e-6 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1328 |
1364 |
1e-15 |
BLAST |
|
low complexity region
|
1374 |
1387 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000200137
AA Change: D740V
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000142498
Gene: ENSMUSG00000028176
AA Change: D740V
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
52 |
69 |
7.6e-1 |
SMART |
|
LRR
|
73 |
92 |
4.2e-1 |
SMART |
|
LRR
|
96 |
115 |
3.4e-1 |
SMART |
|
LRR
|
142 |
164 |
1.8e-1 |
SMART |
|
LRR
|
165 |
184 |
1.5e-1 |
SMART |
|
LRR
|
188 |
207 |
2e-2 |
SMART |
|
LRR
|
211 |
233 |
1.3e-1 |
SMART |
|
LRR
|
234 |
257 |
1.7e-1 |
SMART |
|
LRR
|
257 |
276 |
1e0 |
SMART |
|
LRR
|
280 |
299 |
3.1e-2 |
SMART |
|
LRR
|
303 |
322 |
6.6e-1 |
SMART |
|
LRR
|
326 |
345 |
2.1e-1 |
SMART |
|
LRR
|
372 |
391 |
1.2e-1 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1302 |
1331 |
2e-11 |
BLAST |
|
PDZ
|
1413 |
1493 |
6.4e-22 |
SMART |
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
99% (78/79) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit limb grasping, reduced long term depression, increased anxiety, increased aggression towards other mice, impaired spatial memory, decreased prepulse inhibition, decreased nesting building behavior, and abnormal dendritic spines. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(2) : Gene trapped(2) |
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310002L09Rik |
G |
A |
4: 73,861,087 (GRCm39) |
S171F |
probably damaging |
Het |
| A130010J15Rik |
T |
C |
1: 192,857,406 (GRCm39) |
S253P |
probably damaging |
Het |
| Acbd5 |
T |
C |
2: 22,970,370 (GRCm39) |
M97T |
possibly damaging |
Het |
| Aire |
T |
C |
10: 77,873,809 (GRCm39) |
E300G |
probably damaging |
Het |
| Ano1 |
A |
G |
7: 144,223,397 (GRCm39) |
S99P |
possibly damaging |
Het |
| Ap5z1 |
A |
G |
5: 142,463,011 (GRCm39) |
N732D |
probably benign |
Het |
| Apcs |
A |
T |
1: 172,722,004 (GRCm39) |
L114Q |
possibly damaging |
Het |
| Apmap |
T |
C |
2: 150,431,886 (GRCm39) |
|
probably benign |
Het |
| Ark2c |
T |
C |
18: 77,563,182 (GRCm39) |
E159G |
possibly damaging |
Het |
| Asxl3 |
C |
A |
18: 22,649,547 (GRCm39) |
T512N |
possibly damaging |
Het |
| Atp1a4 |
T |
C |
1: 172,072,491 (GRCm39) |
T388A |
probably damaging |
Het |
| B3galt9 |
A |
G |
2: 34,728,636 (GRCm39) |
D145G |
probably damaging |
Het |
| Bcl2a1a |
A |
T |
9: 88,839,503 (GRCm39) |
I134L |
probably damaging |
Het |
| Chd6 |
G |
A |
2: 160,862,989 (GRCm39) |
A444V |
probably benign |
Het |
| Cmbl |
C |
A |
15: 31,582,073 (GRCm39) |
H23Q |
probably benign |
Het |
| Cnnm2 |
T |
A |
19: 46,750,996 (GRCm39) |
I262N |
probably damaging |
Het |
| Col6a3 |
C |
T |
1: 90,715,673 (GRCm39) |
R2260H |
unknown |
Het |
| Cracr2a |
T |
A |
6: 127,606,736 (GRCm39) |
L260* |
probably null |
Het |
| Csmd2 |
A |
G |
4: 128,451,469 (GRCm39) |
Y3409C |
|
Het |
| Cyp4b1 |
C |
T |
4: 115,493,169 (GRCm39) |
R225H |
possibly damaging |
Het |
| Dcdc2a |
C |
T |
13: 25,386,266 (GRCm39) |
A380V |
probably benign |
Het |
| Dnah6 |
A |
G |
6: 72,998,131 (GRCm39) |
L4097P |
probably damaging |
Het |
| Dppa3 |
G |
A |
6: 122,605,602 (GRCm39) |
R52Q |
probably benign |
Het |
| Fbxo31 |
C |
T |
8: 122,281,967 (GRCm39) |
R311H |
probably benign |
Het |
| Fhad1 |
T |
C |
4: 141,656,885 (GRCm39) |
R90G |
probably damaging |
Het |
| Fitm2 |
A |
T |
2: 163,311,602 (GRCm39) |
W204R |
possibly damaging |
Het |
| Gatb |
T |
A |
3: 85,511,716 (GRCm39) |
L157H |
probably damaging |
Het |
| Gm5111 |
G |
A |
6: 48,566,629 (GRCm39) |
|
probably null |
Het |
| Gm7298 |
A |
C |
6: 121,748,788 (GRCm39) |
I688L |
probably benign |
Het |
| Hecw1 |
T |
C |
13: 14,422,275 (GRCm39) |
|
probably null |
Het |
| Ift122 |
T |
A |
6: 115,857,632 (GRCm39) |
V126E |
probably damaging |
Het |
| Iqcf6 |
A |
T |
9: 106,504,698 (GRCm39) |
I121F |
possibly damaging |
Het |
| Kif21a |
A |
G |
15: 90,852,382 (GRCm39) |
V902A |
probably damaging |
Het |
| Klhl38 |
T |
C |
15: 58,178,435 (GRCm39) |
M512V |
probably benign |
Het |
| Klk1b1 |
A |
C |
7: 43,619,747 (GRCm39) |
N102T |
probably damaging |
Het |
| Lama4 |
T |
A |
10: 38,923,996 (GRCm39) |
L468Q |
probably damaging |
Het |
| Lilra5 |
A |
T |
7: 4,241,165 (GRCm39) |
Q34L |
possibly damaging |
Het |
| Mapk7 |
G |
T |
11: 61,384,632 (GRCm39) |
P25T |
probably benign |
Het |
| Mcm3ap |
C |
A |
10: 76,306,538 (GRCm39) |
A217D |
probably benign |
Het |
| Mucl3 |
A |
T |
17: 35,948,872 (GRCm39) |
F242L |
probably benign |
Het |
| Ncaph2 |
A |
G |
15: 89,254,605 (GRCm39) |
E406G |
probably benign |
Het |
| Ncor2 |
T |
C |
5: 125,179,739 (GRCm39) |
I69V |
unknown |
Het |
| Nfatc3 |
A |
G |
8: 106,805,640 (GRCm39) |
S170G |
probably damaging |
Het |
| Nptn |
G |
A |
9: 58,526,264 (GRCm39) |
R137Q |
probably damaging |
Het |
| Nsd1 |
A |
T |
13: 55,430,570 (GRCm39) |
K1581N |
probably damaging |
Het |
| Or1q1 |
T |
C |
2: 36,887,691 (GRCm39) |
Y290H |
probably damaging |
Het |
| Or2t43 |
A |
G |
11: 58,457,562 (GRCm39) |
L203P |
probably damaging |
Het |
| Or51l4 |
G |
A |
7: 103,403,893 (GRCm39) |
Q300* |
probably null |
Het |
| Or52ab2 |
T |
A |
7: 102,970,449 (GRCm39) |
L277Q |
|
Het |
| Or5be3 |
G |
T |
2: 86,863,803 (GRCm39) |
T254K |
probably damaging |
Het |
| Or6c211 |
A |
T |
10: 129,505,628 (GRCm39) |
C253* |
probably null |
Het |
| Pdcl |
T |
C |
2: 37,242,348 (GRCm39) |
E134G |
probably damaging |
Het |
| Pikfyve |
T |
A |
1: 65,283,576 (GRCm39) |
Y738N |
probably damaging |
Het |
| Pkd1 |
A |
G |
17: 24,792,807 (GRCm39) |
D1498G |
probably damaging |
Het |
| Plxna1 |
T |
C |
6: 89,310,079 (GRCm39) |
N1029D |
probably benign |
Het |
| Ppp3cb |
C |
A |
14: 20,596,517 (GRCm39) |
|
probably benign |
Het |
| Prkn |
A |
G |
17: 11,456,448 (GRCm39) |
T91A |
probably benign |
Het |
| Rgs18 |
T |
A |
1: 144,629,698 (GRCm39) |
D187V |
probably damaging |
Het |
| Ripor2 |
C |
T |
13: 24,822,760 (GRCm39) |
|
probably benign |
Het |
| Rpl3l |
G |
A |
17: 24,954,455 (GRCm39) |
G172D |
probably damaging |
Het |
| Sdf4 |
A |
G |
4: 156,093,759 (GRCm39) |
T298A |
probably damaging |
Het |
| Skic3 |
C |
T |
13: 76,279,428 (GRCm39) |
S620L |
probably damaging |
Het |
| Slc17a3 |
T |
C |
13: 24,039,943 (GRCm39) |
V327A |
|
Het |
| Slc4a1ap |
T |
A |
5: 31,708,059 (GRCm39) |
F677L |
probably benign |
Het |
| Stoml2 |
A |
G |
4: 43,028,256 (GRCm39) |
V324A |
probably benign |
Het |
| Syne2 |
A |
G |
12: 75,989,620 (GRCm39) |
Q1833R |
probably damaging |
Het |
| Syt6 |
A |
G |
3: 103,534,371 (GRCm39) |
N481D |
possibly damaging |
Het |
| Tert |
T |
C |
13: 73,776,566 (GRCm39) |
M439T |
probably benign |
Het |
| Thsd7a |
A |
T |
6: 12,338,686 (GRCm39) |
D1181E |
|
Het |
| Tln2 |
G |
A |
9: 67,237,832 (GRCm39) |
T33I |
probably damaging |
Het |
| Top3a |
A |
G |
11: 60,633,481 (GRCm39) |
S872P |
probably benign |
Het |
| Trim10 |
T |
C |
17: 37,181,048 (GRCm39) |
L93P |
probably benign |
Het |
| Trpc7 |
C |
T |
13: 57,008,746 (GRCm39) |
S307N |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,640,427 (GRCm39) |
V13727E |
probably damaging |
Het |
| Vmn1r220 |
T |
C |
13: 23,368,271 (GRCm39) |
S142G |
probably benign |
Het |
| Vmn1r32 |
A |
G |
6: 66,530,651 (GRCm39) |
S42P |
probably damaging |
Het |
| Zc3h7b |
G |
A |
15: 81,656,681 (GRCm39) |
R166Q |
probably benign |
Het |
| Zfp683 |
C |
T |
4: 133,785,995 (GRCm39) |
T374I |
probably damaging |
Het |
|
| Other mutations in Lrrc7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00594:Lrrc7
|
APN |
3 |
157,892,647 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00644:Lrrc7
|
APN |
3 |
157,908,005 (GRCm39) |
nonsense |
probably null |
|
|
IGL00822:Lrrc7
|
APN |
3 |
157,891,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00927:Lrrc7
|
APN |
3 |
157,866,727 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00946:Lrrc7
|
APN |
3 |
157,866,993 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00948:Lrrc7
|
APN |
3 |
157,867,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01838:Lrrc7
|
APN |
3 |
157,891,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Lrrc7
|
APN |
3 |
157,946,080 (GRCm39) |
splice site |
probably benign |
|
|
IGL02514:Lrrc7
|
APN |
3 |
157,865,929 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02545:Lrrc7
|
APN |
3 |
157,891,011 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Lrrc7
|
APN |
3 |
157,866,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03129:Lrrc7
|
APN |
3 |
157,866,696 (GRCm39) |
missense |
probably benign |
0.02 |
|
N/A:Lrrc7
|
UTSW |
3 |
157,865,977 (GRCm39) |
missense |
probably benign |
|
|
R0021:Lrrc7
|
UTSW |
3 |
157,866,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0041:Lrrc7
|
UTSW |
3 |
157,869,897 (GRCm39) |
splice site |
probably benign |
|
|
R0255:Lrrc7
|
UTSW |
3 |
157,866,475 (GRCm39) |
nonsense |
probably null |
|
|
R0278:Lrrc7
|
UTSW |
3 |
157,885,432 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0409:Lrrc7
|
UTSW |
3 |
157,867,063 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0612:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0866:Lrrc7
|
UTSW |
3 |
157,869,903 (GRCm39) |
splice site |
probably benign |
|
|
R1077:Lrrc7
|
UTSW |
3 |
157,866,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1103:Lrrc7
|
UTSW |
3 |
157,854,343 (GRCm39) |
splice site |
probably benign |
|
|
R1157:Lrrc7
|
UTSW |
3 |
157,865,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1187:Lrrc7
|
UTSW |
3 |
157,866,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1301:Lrrc7
|
UTSW |
3 |
157,840,968 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1433:Lrrc7
|
UTSW |
3 |
157,882,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1450:Lrrc7
|
UTSW |
3 |
157,892,681 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1595:Lrrc7
|
UTSW |
3 |
157,882,914 (GRCm39) |
nonsense |
probably null |
|
|
R1659:Lrrc7
|
UTSW |
3 |
157,867,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1693:Lrrc7
|
UTSW |
3 |
157,790,170 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1774:Lrrc7
|
UTSW |
3 |
157,865,929 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2273:Lrrc7
|
UTSW |
3 |
157,892,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2276:Lrrc7
|
UTSW |
3 |
157,885,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2302:Lrrc7
|
UTSW |
3 |
157,840,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2326:Lrrc7
|
UTSW |
3 |
157,876,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2371:Lrrc7
|
UTSW |
3 |
157,866,697 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2383:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R2679:Lrrc7
|
UTSW |
3 |
157,880,745 (GRCm39) |
nonsense |
probably null |
|
|
R2698:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2858:Lrrc7
|
UTSW |
3 |
157,867,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3758:Lrrc7
|
UTSW |
3 |
157,869,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3791:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R3805:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3806:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3807:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3892:Lrrc7
|
UTSW |
3 |
157,866,333 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3912:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3913:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3963:Lrrc7
|
UTSW |
3 |
157,866,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4665:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4666:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4671:Lrrc7
|
UTSW |
3 |
157,908,132 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4688:Lrrc7
|
UTSW |
3 |
157,854,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4725:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4726:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4728:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4783:Lrrc7
|
UTSW |
3 |
157,832,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4867:Lrrc7
|
UTSW |
3 |
157,866,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4907:Lrrc7
|
UTSW |
3 |
157,866,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Lrrc7
|
UTSW |
3 |
157,887,217 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5107:Lrrc7
|
UTSW |
3 |
157,867,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5295:Lrrc7
|
UTSW |
3 |
157,876,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5348:Lrrc7
|
UTSW |
3 |
157,880,963 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5468:Lrrc7
|
UTSW |
3 |
158,024,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5778:Lrrc7
|
UTSW |
3 |
157,876,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6179:Lrrc7
|
UTSW |
3 |
158,059,069 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6312:Lrrc7
|
UTSW |
3 |
157,866,246 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6313:Lrrc7
|
UTSW |
3 |
157,866,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6366:Lrrc7
|
UTSW |
3 |
157,841,012 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6389:Lrrc7
|
UTSW |
3 |
157,891,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Lrrc7
|
UTSW |
3 |
157,840,940 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6956:Lrrc7
|
UTSW |
3 |
157,994,668 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6969:Lrrc7
|
UTSW |
3 |
157,862,550 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7073:Lrrc7
|
UTSW |
3 |
157,832,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7313:Lrrc7
|
UTSW |
3 |
157,866,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7365:Lrrc7
|
UTSW |
3 |
157,903,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7398:Lrrc7
|
UTSW |
3 |
157,997,595 (GRCm39) |
nonsense |
probably null |
|
|
R7403:Lrrc7
|
UTSW |
3 |
157,854,311 (GRCm39) |
nonsense |
probably null |
|
|
R7407:Lrrc7
|
UTSW |
3 |
157,840,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Lrrc7
|
UTSW |
3 |
157,903,778 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7453:Lrrc7
|
UTSW |
3 |
157,891,046 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7461:Lrrc7
|
UTSW |
3 |
157,892,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7807:Lrrc7
|
UTSW |
3 |
157,866,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Lrrc7
|
UTSW |
3 |
158,059,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Lrrc7
|
UTSW |
3 |
157,915,387 (GRCm39) |
missense |
probably benign |
|
|
R8367:Lrrc7
|
UTSW |
3 |
157,908,007 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8880:Lrrc7
|
UTSW |
3 |
157,867,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8941:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R8958:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9068:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9069:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9180:Lrrc7
|
UTSW |
3 |
157,867,011 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9193:Lrrc7
|
UTSW |
3 |
158,059,011 (GRCm39) |
nonsense |
probably null |
|
|
R9309:Lrrc7
|
UTSW |
3 |
157,915,361 (GRCm39) |
nonsense |
probably null |
|
|
R9418:Lrrc7
|
UTSW |
3 |
157,908,023 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9474:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9515:Lrrc7
|
UTSW |
3 |
157,867,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9635:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9639:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9682:Lrrc7
|
UTSW |
3 |
157,882,954 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9731:Lrrc7
|
UTSW |
3 |
157,880,888 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACGCTTCTAGCCTTGGAAC -3'
(R):5'- AGTCAGAGCCGGTTAAACTG -3'
Sequencing Primer
(F):5'- CGCTTCTAGCCTTGGAACTTAAGAG -3'
(R):5'- TGTGGTGAAATAATGTGACTTTAACC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation