Incidental Mutation 'R8870:Cachd1'
| ID |
676189 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cachd1
|
| Ensembl Gene |
ENSMUSG00000028532 |
| Gene Name |
cache domain containing 1 |
| Synonyms |
Vwcd1, 1190007F10Rik, B430218L07Rik |
| MMRRC Submission |
068684-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.258)
|
| Stock # |
R8870 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
100633870-100861741 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 100754978 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Phenylalanine
at position 143
(C143F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000030257
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030257]
[ENSMUST00000097955]
|
| AlphaFold |
Q6PDJ1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000030257
AA Change: C143F
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000030257
Gene: ENSMUSG00000028532
AA Change: C143F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
24 |
N/A |
INTRINSIC |
|
Pfam:VWA_N
|
103 |
218 |
9.4e-22 |
PFAM |
|
VWA
|
240 |
438 |
2.8e-1 |
SMART |
|
Pfam:Cache_1
|
467 |
543 |
2.4e-12 |
PFAM |
|
Pfam:Cache_1
|
786 |
871 |
1.5e-7 |
PFAM |
|
low complexity region
|
981 |
996 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1109 |
1131 |
N/A |
INTRINSIC |
|
low complexity region
|
1159 |
1173 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1246 |
N/A |
INTRINSIC |
|
low complexity region
|
1260 |
1274 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000097955
AA Change: C143F
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000095568
Gene: ENSMUSG00000028532
AA Change: C143F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
24 |
N/A |
INTRINSIC |
|
Pfam:VWA_N
|
103 |
218 |
6.7e-32 |
PFAM |
|
VWA
|
240 |
438 |
2.8e-1 |
SMART |
|
Pfam:Cache_1
|
467 |
543 |
1.7e-12 |
PFAM |
|
low complexity region
|
801 |
818 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
996 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1109 |
1131 |
N/A |
INTRINSIC |
|
low complexity region
|
1159 |
1173 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
100% (76/76) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
A |
T |
13: 77,471,840 (GRCm39) |
N1082Y |
possibly damaging |
Het |
| 4930444P10Rik |
G |
A |
1: 16,136,451 (GRCm39) |
Q122* |
probably null |
Het |
| Afg2a |
A |
G |
3: 37,502,661 (GRCm39) |
N607D |
probably benign |
Het |
| Ak8 |
C |
T |
2: 28,625,602 (GRCm39) |
T215M |
probably benign |
Het |
| Ano3 |
T |
A |
2: 110,614,074 (GRCm39) |
I210F |
probably benign |
Het |
| Atg9b |
A |
G |
5: 24,592,032 (GRCm39) |
F656L |
probably damaging |
Het |
| Bscl2 |
T |
C |
19: 8,824,793 (GRCm39) |
M292T |
probably benign |
Het |
| Calcoco2 |
GGGCCTTCTCTTTCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTTCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTTCTCCCAGGAGGCCTTCTCTTCC |
GGGCCTTCTCTTTCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTCCTCCCAGGAGGCCTTCTCTTTCTCCCAGGAGGCCTTCTCTTCC |
11: 95,990,808 (GRCm39) |
|
probably benign |
Het |
| Ccnb1ip1 |
C |
T |
14: 51,029,450 (GRCm39) |
G204E |
probably benign |
Het |
| Ccr1 |
T |
A |
9: 123,764,022 (GRCm39) |
L169F |
probably benign |
Het |
| Cdc42bpg |
A |
G |
19: 6,364,550 (GRCm39) |
N593D |
possibly damaging |
Het |
| Cdh20 |
T |
C |
1: 104,873,048 (GRCm39) |
S265P |
probably damaging |
Het |
| Cenpk |
A |
G |
13: 104,367,365 (GRCm39) |
E67G |
probably damaging |
Het |
| Cep76 |
A |
T |
18: 67,773,190 (GRCm39) |
I36K |
probably benign |
Het |
| Clock |
A |
T |
5: 76,383,632 (GRCm39) |
I507N |
probably benign |
Het |
| Cpne1 |
T |
C |
2: 155,920,873 (GRCm39) |
T110A |
probably benign |
Het |
| Crybg2 |
A |
T |
4: 133,818,525 (GRCm39) |
E1427V |
possibly damaging |
Het |
| Ctu1 |
A |
C |
7: 43,324,746 (GRCm39) |
K62Q |
probably damaging |
Het |
| Dnai4 |
C |
T |
4: 102,944,529 (GRCm39) |
|
probably null |
Het |
| Drd5 |
C |
A |
5: 38,477,747 (GRCm39) |
Q247K |
possibly damaging |
Het |
| Ect2l |
A |
T |
10: 18,014,608 (GRCm39) |
L808* |
probably null |
Het |
| Efcab3 |
A |
G |
11: 104,791,500 (GRCm39) |
T2905A |
probably benign |
Het |
| Ficd |
A |
T |
5: 113,876,248 (GRCm39) |
D141V |
probably damaging |
Het |
| Fnbp1 |
A |
G |
2: 30,938,222 (GRCm39) |
Y148H |
|
Het |
| Gm49368 |
A |
G |
7: 127,700,685 (GRCm39) |
K485R |
probably benign |
Het |
| Gpr75 |
C |
A |
11: 30,841,860 (GRCm39) |
A255D |
probably benign |
Het |
| Hcrtr2 |
G |
T |
9: 76,153,666 (GRCm39) |
A242D |
probably damaging |
Het |
| Iapp |
G |
T |
6: 142,244,602 (GRCm39) |
V10F |
probably benign |
Het |
| Ikzf2 |
A |
G |
1: 69,722,417 (GRCm39) |
S31P |
possibly damaging |
Het |
| Il18rap |
G |
A |
1: 40,564,280 (GRCm39) |
|
probably benign |
Het |
| Irak2 |
A |
T |
6: 113,663,902 (GRCm39) |
N423Y |
probably damaging |
Het |
| Itpkb |
A |
G |
1: 180,159,744 (GRCm39) |
|
probably benign |
Het |
| Itpr1 |
A |
G |
6: 108,365,172 (GRCm39) |
I874M |
probably damaging |
Het |
| Kif26b |
G |
T |
1: 178,692,594 (GRCm39) |
V512F |
probably damaging |
Het |
| Lhx6 |
G |
A |
2: 35,995,232 (GRCm39) |
|
probably benign |
Het |
| Lrfn1 |
A |
G |
7: 28,158,918 (GRCm39) |
E279G |
possibly damaging |
Het |
| Masp1 |
A |
C |
16: 23,314,882 (GRCm39) |
D126E |
probably damaging |
Het |
| Mef2a |
T |
C |
7: 66,890,176 (GRCm39) |
I299V |
probably benign |
Het |
| Midn |
A |
G |
10: 79,985,939 (GRCm39) |
S10G |
probably damaging |
Het |
| Mrps12 |
A |
T |
7: 28,439,361 (GRCm39) |
L118Q |
probably damaging |
Het |
| Mxi1 |
G |
A |
19: 53,360,126 (GRCm39) |
G283S |
probably damaging |
Het |
| Mzf1 |
A |
G |
7: 12,786,836 (GRCm39) |
V78A |
probably benign |
Het |
| Ncoa6 |
A |
G |
2: 155,263,078 (GRCm39) |
V452A |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,051,481 (GRCm39) |
Y6600H |
probably damaging |
Het |
| Nlgn2 |
A |
G |
11: 69,716,297 (GRCm39) |
L748P |
possibly damaging |
Het |
| Nnmt |
A |
T |
9: 48,514,801 (GRCm39) |
L72H |
probably damaging |
Het |
| Nrxn3 |
A |
G |
12: 90,171,560 (GRCm39) |
T964A |
probably benign |
Het |
| Or12k7 |
A |
G |
2: 36,958,982 (GRCm39) |
I222V |
probably benign |
Het |
| Or1e35 |
T |
G |
11: 73,797,725 (GRCm39) |
M198L |
probably benign |
Het |
| Or2y16 |
T |
A |
11: 49,335,350 (GRCm39) |
V224E |
probably damaging |
Het |
| Or4k35 |
T |
A |
2: 111,100,464 (GRCm39) |
I83F |
possibly damaging |
Het |
| Or5h27 |
G |
A |
16: 59,006,130 (GRCm39) |
P239S |
unknown |
Het |
| Or8c11 |
A |
G |
9: 38,289,720 (GRCm39) |
N175S |
probably benign |
Het |
| Or8g33 |
A |
G |
9: 39,337,548 (GRCm39) |
V273A |
probably damaging |
Het |
| Osbpl11 |
A |
G |
16: 33,034,850 (GRCm39) |
N280D |
probably benign |
Het |
| Peg10 |
A |
T |
6: 4,754,825 (GRCm39) |
Y202F |
probably damaging |
Het |
| Pick1 |
A |
G |
15: 79,140,107 (GRCm39) |
R469G |
unknown |
Het |
| Rev3l |
A |
G |
10: 39,738,786 (GRCm39) |
I2847V |
probably damaging |
Het |
| Rmc1 |
A |
G |
18: 12,321,618 (GRCm39) |
E473G |
probably benign |
Het |
| Rnaseh2b |
T |
A |
14: 62,569,617 (GRCm39) |
L18Q |
probably damaging |
Het |
| Rpl19 |
A |
G |
11: 97,920,615 (GRCm39) |
Y122C |
probably benign |
Het |
| Selp |
A |
G |
1: 163,964,787 (GRCm39) |
Y483C |
probably damaging |
Het |
| Setd2 |
T |
A |
9: 110,423,321 (GRCm39) |
F347L |
|
Het |
| Snx14 |
A |
G |
9: 88,295,541 (GRCm39) |
I208T |
probably benign |
Het |
| Spag16 |
T |
A |
1: 70,036,017 (GRCm39) |
F348L |
probably benign |
Het |
| Spata22 |
A |
T |
11: 73,231,091 (GRCm39) |
N115I |
probably damaging |
Het |
| Spata31 |
T |
C |
13: 65,068,818 (GRCm39) |
V322A |
probably benign |
Het |
| Stc1 |
A |
T |
14: 69,275,825 (GRCm39) |
H206L |
probably benign |
Het |
| Tas2r129 |
A |
G |
6: 132,928,522 (GRCm39) |
D153G |
probably damaging |
Het |
| Tmem196 |
T |
A |
12: 119,982,268 (GRCm39) |
N167K |
possibly damaging |
Het |
| Tmpo |
T |
C |
10: 90,987,581 (GRCm39) |
T356A |
probably damaging |
Het |
| Tnks |
A |
G |
8: 35,314,433 (GRCm39) |
|
probably null |
Het |
| Ttbk1 |
A |
C |
17: 46,781,661 (GRCm39) |
L364R |
probably damaging |
Het |
| Vmn1r176 |
A |
T |
7: 23,534,480 (GRCm39) |
N224K |
probably damaging |
Het |
| Vmn1r36 |
T |
A |
6: 66,693,720 (GRCm39) |
M52L |
probably benign |
Het |
| Vmn2r93 |
A |
T |
17: 18,525,320 (GRCm39) |
H326L |
possibly damaging |
Het |
| Wrn |
A |
T |
8: 33,819,220 (GRCm39) |
M244K |
probably benign |
Het |
| Zcchc24 |
C |
T |
14: 25,757,578 (GRCm39) |
A102T |
probably benign |
Het |
| Zfp1010 |
T |
A |
2: 176,957,312 (GRCm39) |
Q62L |
probably benign |
Het |
|
| Other mutations in Cachd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00922:Cachd1
|
APN |
4 |
100,824,163 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01531:Cachd1
|
APN |
4 |
100,810,231 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01705:Cachd1
|
APN |
4 |
100,840,736 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01843:Cachd1
|
APN |
4 |
100,850,069 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01938:Cachd1
|
APN |
4 |
100,831,325 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02268:Cachd1
|
APN |
4 |
100,809,294 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL02934:Cachd1
|
APN |
4 |
100,825,295 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03019:Cachd1
|
APN |
4 |
100,809,282 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03084:Cachd1
|
APN |
4 |
100,860,285 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0366:Cachd1
|
UTSW |
4 |
100,851,934 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0395:Cachd1
|
UTSW |
4 |
100,810,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0520:Cachd1
|
UTSW |
4 |
100,754,900 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0578:Cachd1
|
UTSW |
4 |
100,852,039 (GRCm39) |
splice site |
probably benign |
|
|
R0646:Cachd1
|
UTSW |
4 |
100,845,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0689:Cachd1
|
UTSW |
4 |
100,832,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0962:Cachd1
|
UTSW |
4 |
100,840,498 (GRCm39) |
splice site |
probably benign |
|
|
R1156:Cachd1
|
UTSW |
4 |
100,845,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1157:Cachd1
|
UTSW |
4 |
100,832,037 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1314:Cachd1
|
UTSW |
4 |
100,832,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1482:Cachd1
|
UTSW |
4 |
100,845,795 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1632:Cachd1
|
UTSW |
4 |
100,824,169 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1774:Cachd1
|
UTSW |
4 |
100,821,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1774:Cachd1
|
UTSW |
4 |
100,824,240 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1845:Cachd1
|
UTSW |
4 |
100,634,555 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1869:Cachd1
|
UTSW |
4 |
100,840,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1912:Cachd1
|
UTSW |
4 |
100,810,366 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2069:Cachd1
|
UTSW |
4 |
100,848,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2082:Cachd1
|
UTSW |
4 |
100,860,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2267:Cachd1
|
UTSW |
4 |
100,806,266 (GRCm39) |
splice site |
probably benign |
|
|
R2517:Cachd1
|
UTSW |
4 |
100,838,079 (GRCm39) |
splice site |
probably null |
|
|
R2896:Cachd1
|
UTSW |
4 |
100,828,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3729:Cachd1
|
UTSW |
4 |
100,832,077 (GRCm39) |
nonsense |
probably null |
|
|
R3818:Cachd1
|
UTSW |
4 |
100,848,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Cachd1
|
UTSW |
4 |
100,828,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4647:Cachd1
|
UTSW |
4 |
100,810,327 (GRCm39) |
nonsense |
probably null |
|
|
R4791:Cachd1
|
UTSW |
4 |
100,775,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5133:Cachd1
|
UTSW |
4 |
100,851,935 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5147:Cachd1
|
UTSW |
4 |
100,821,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5187:Cachd1
|
UTSW |
4 |
100,823,397 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5322:Cachd1
|
UTSW |
4 |
100,809,319 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5335:Cachd1
|
UTSW |
4 |
100,825,282 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5390:Cachd1
|
UTSW |
4 |
100,838,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5573:Cachd1
|
UTSW |
4 |
100,831,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5578:Cachd1
|
UTSW |
4 |
100,722,203 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5905:Cachd1
|
UTSW |
4 |
100,840,753 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6003:Cachd1
|
UTSW |
4 |
100,809,216 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6028:Cachd1
|
UTSW |
4 |
100,840,753 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6185:Cachd1
|
UTSW |
4 |
100,838,228 (GRCm39) |
nonsense |
probably null |
|
|
R6367:Cachd1
|
UTSW |
4 |
100,860,167 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6492:Cachd1
|
UTSW |
4 |
100,809,315 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6591:Cachd1
|
UTSW |
4 |
100,846,683 (GRCm39) |
missense |
probably benign |
|
|
R6691:Cachd1
|
UTSW |
4 |
100,846,683 (GRCm39) |
missense |
probably benign |
|
|
R7129:Cachd1
|
UTSW |
4 |
100,775,263 (GRCm39) |
missense |
probably null |
0.99 |
|
R7187:Cachd1
|
UTSW |
4 |
100,833,552 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7387:Cachd1
|
UTSW |
4 |
100,634,375 (GRCm39) |
missense |
unknown |
|
|
R7833:Cachd1
|
UTSW |
4 |
100,832,012 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7835:Cachd1
|
UTSW |
4 |
100,831,350 (GRCm39) |
splice site |
probably null |
|
|
R7838:Cachd1
|
UTSW |
4 |
100,824,211 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7867:Cachd1
|
UTSW |
4 |
100,845,759 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7882:Cachd1
|
UTSW |
4 |
100,824,244 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7941:Cachd1
|
UTSW |
4 |
100,845,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7978:Cachd1
|
UTSW |
4 |
100,832,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8085:Cachd1
|
UTSW |
4 |
100,845,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Cachd1
|
UTSW |
4 |
100,845,835 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8174:Cachd1
|
UTSW |
4 |
100,823,466 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8219:Cachd1
|
UTSW |
4 |
100,848,159 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8358:Cachd1
|
UTSW |
4 |
100,816,668 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8376:Cachd1
|
UTSW |
4 |
100,832,073 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8686:Cachd1
|
UTSW |
4 |
100,845,325 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8747:Cachd1
|
UTSW |
4 |
100,860,045 (GRCm39) |
intron |
probably benign |
|
|
R8845:Cachd1
|
UTSW |
4 |
100,810,343 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8864:Cachd1
|
UTSW |
4 |
100,852,026 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8869:Cachd1
|
UTSW |
4 |
100,809,280 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8904:Cachd1
|
UTSW |
4 |
100,810,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8958:Cachd1
|
UTSW |
4 |
100,851,283 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9061:Cachd1
|
UTSW |
4 |
100,809,202 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9193:Cachd1
|
UTSW |
4 |
100,634,339 (GRCm39) |
missense |
unknown |
|
|
R9304:Cachd1
|
UTSW |
4 |
100,824,179 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9358:Cachd1
|
UTSW |
4 |
100,833,622 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9373:Cachd1
|
UTSW |
4 |
100,832,067 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9425:Cachd1
|
UTSW |
4 |
100,832,057 (GRCm39) |
missense |
probably benign |
|
|
R9632:Cachd1
|
UTSW |
4 |
100,832,092 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9710:Cachd1
|
UTSW |
4 |
100,832,092 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9751:Cachd1
|
UTSW |
4 |
100,823,438 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCAAAGATGACCTGGGTGTC -3'
(R):5'- TCTCTAGGCAAGCAAGTAATGAGAG -3'
Sequencing Primer
(F):5'- ACCTGGGTGTCGTTTATATGTTACC -3'
(R):5'- CAAGTAATGAGAGATTCACGGGC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation