Incidental Mutation 'R8871:Kif13a'
| ID |
676310 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kif13a
|
| Ensembl Gene |
ENSMUSG00000021375 |
| Gene Name |
kinesin family member 13A |
| Synonyms |
4930505I07Rik, N-3 kinesin |
| MMRRC Submission |
068685-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.268)
|
| Stock # |
R8871 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
46902563-47083343 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46984279 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 162
(D162G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055304
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056978]
[ENSMUST00000225591]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000056978
AA Change: D162G
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000055304
Gene: ENSMUSG00000021375
AA Change: D162G
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
360 |
2.69e-175 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
low complexity region
|
391 |
406 |
N/A |
INTRINSIC |
|
FHA
|
469 |
519 |
7.16e-2 |
SMART |
|
coiled coil region
|
605 |
639 |
N/A |
INTRINSIC |
|
coiled coil region
|
664 |
704 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
748 |
792 |
1.7e-19 |
PFAM |
|
low complexity region
|
840 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
915 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1003 |
1270 |
2.2e-39 |
PFAM |
|
low complexity region
|
1401 |
1412 |
N/A |
INTRINSIC |
|
low complexity region
|
1475 |
1492 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225591
AA Change: D99G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.3%
- 20x: 97.3%
|
| Validation Efficiency |
99% (76/77) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
G |
11: 9,248,071 (GRCm39) |
M2606R |
probably benign |
Het |
| Abcg5 |
C |
T |
17: 84,990,295 (GRCm39) |
E3K |
probably benign |
Het |
| Adam20 |
A |
C |
8: 41,248,601 (GRCm39) |
H237P |
probably damaging |
Het |
| Alg3 |
T |
C |
16: 20,424,684 (GRCm39) |
Y361C |
probably damaging |
Het |
| Ano8 |
A |
T |
8: 71,931,944 (GRCm39) |
Y752N |
probably benign |
Het |
| AW551984 |
A |
T |
9: 39,500,998 (GRCm39) |
L759* |
probably null |
Het |
| Bdp1 |
A |
C |
13: 100,186,175 (GRCm39) |
V1759G |
probably damaging |
Het |
| Bicdl2 |
C |
A |
17: 23,885,777 (GRCm39) |
Q273K |
probably damaging |
Het |
| Cc2d2a |
A |
T |
5: 43,857,285 (GRCm39) |
T491S |
possibly damaging |
Het |
| Cdkl2 |
A |
G |
5: 92,164,989 (GRCm39) |
S545P |
possibly damaging |
Het |
| Ceacam5 |
T |
A |
7: 17,494,827 (GRCm39) |
I945K |
probably benign |
Het |
| Celf1 |
A |
G |
2: 90,840,840 (GRCm39) |
Y369C |
probably damaging |
Het |
| Cmtm1 |
TCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGG |
TCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGG |
8: 105,036,334 (GRCm39) |
|
probably null |
Het |
| Col14a1 |
T |
G |
15: 55,245,958 (GRCm39) |
D487E |
unknown |
Het |
| Crybg3 |
T |
C |
16: 59,378,519 (GRCm39) |
N912D |
probably benign |
Het |
| Cstl1 |
A |
G |
2: 148,596,554 (GRCm39) |
T86A |
probably damaging |
Het |
| Dixdc1 |
C |
T |
9: 50,595,096 (GRCm39) |
V482M |
possibly damaging |
Het |
| Dmbt1 |
T |
C |
7: 130,718,597 (GRCm39) |
Y1773H |
unknown |
Het |
| Dock4 |
T |
C |
12: 40,795,730 (GRCm39) |
I849T |
probably benign |
Het |
| Fbln2 |
A |
T |
6: 91,233,215 (GRCm39) |
|
probably null |
Het |
| Fbxo16 |
A |
G |
14: 65,531,348 (GRCm39) |
E84G |
probably damaging |
Het |
| Fras1 |
T |
A |
5: 96,855,257 (GRCm39) |
V1922D |
probably benign |
Het |
| G6pc3 |
A |
G |
11: 102,082,896 (GRCm39) |
H85R |
probably damaging |
Het |
| Galc |
A |
T |
12: 98,212,543 (GRCm39) |
N197K |
probably damaging |
Het |
| Galnt12 |
T |
G |
4: 47,108,582 (GRCm39) |
|
probably null |
Het |
| Gm10220 |
T |
A |
5: 26,322,863 (GRCm39) |
Q183L |
probably benign |
Het |
| Gxylt2 |
A |
G |
6: 100,760,109 (GRCm39) |
T215A |
probably damaging |
Het |
| Hnrnpf |
T |
G |
6: 117,900,811 (GRCm39) |
S32A |
probably benign |
Het |
| Hspa1l |
T |
C |
17: 35,197,799 (GRCm39) |
Y613H |
probably benign |
Het |
| Il1r2 |
T |
A |
1: 40,144,424 (GRCm39) |
V37D |
probably benign |
Het |
| Itga11 |
C |
A |
9: 62,668,823 (GRCm39) |
Y693* |
probably null |
Het |
| Itgax |
T |
A |
7: 127,735,223 (GRCm39) |
F459L |
probably damaging |
Het |
| Jph1 |
A |
G |
1: 17,067,719 (GRCm39) |
V656A |
possibly damaging |
Het |
| Kcnn4 |
A |
T |
7: 24,083,500 (GRCm39) |
I394F |
possibly damaging |
Het |
| Kdelr3 |
T |
A |
15: 79,410,044 (GRCm39) |
Y176* |
probably null |
Het |
| Klhdc8b |
G |
A |
9: 108,326,871 (GRCm39) |
P164S |
probably damaging |
Het |
| Lmbrd1 |
A |
T |
1: 24,783,435 (GRCm39) |
Q357L |
probably damaging |
Het |
| Lrrc37a |
T |
C |
11: 103,347,375 (GRCm39) |
M3107V |
unknown |
Het |
| Mllt3 |
ACTGCTGCTGCTGCTGCTGCTGCTACTGCTGCTGCTGCTGCTGCT |
ACTGCTGCTGCTGCTGCTGCTACTGCTGCTGCTGCTGCTGCT |
4: 87,759,552 (GRCm39) |
|
probably benign |
Het |
| Muc16 |
C |
A |
9: 18,567,344 (GRCm39) |
G1725V |
unknown |
Het |
| Myo5c |
T |
C |
9: 75,185,585 (GRCm39) |
S983P |
probably benign |
Het |
| Naip1 |
G |
A |
13: 100,580,146 (GRCm39) |
H217Y |
probably damaging |
Het |
| Nlrc3 |
T |
C |
16: 3,781,968 (GRCm39) |
|
probably benign |
Het |
| Nrl |
A |
T |
14: 55,758,184 (GRCm39) |
L181Q |
probably damaging |
Het |
| Olig1 |
T |
C |
16: 91,067,545 (GRCm39) |
*261R |
probably null |
Het |
| Or12k5 |
T |
C |
2: 36,895,060 (GRCm39) |
T189A |
probably benign |
Het |
| Or2l13b |
T |
C |
16: 19,349,536 (GRCm39) |
I45V |
|
Het |
| Or8j3c |
T |
C |
2: 86,253,697 (GRCm39) |
M108V |
probably benign |
Het |
| Oscp1 |
T |
A |
4: 125,952,535 (GRCm39) |
L21Q |
probably damaging |
Het |
| Oxct1 |
G |
A |
15: 4,064,763 (GRCm39) |
V34I |
probably benign |
Het |
| Pdzph1 |
A |
G |
17: 59,195,033 (GRCm39) |
L1074P |
probably damaging |
Het |
| Pkd1l1 |
T |
A |
11: 8,900,503 (GRCm39) |
S463C |
|
Het |
| Pnpla3 |
G |
A |
15: 84,063,509 (GRCm39) |
E296K |
probably benign |
Het |
| Prss35 |
T |
G |
9: 86,637,244 (GRCm39) |
L5V |
possibly damaging |
Het |
| Rbck1 |
T |
C |
2: 152,164,096 (GRCm39) |
E336G |
possibly damaging |
Het |
| Rgl2 |
G |
A |
17: 34,153,974 (GRCm39) |
R460Q |
probably damaging |
Het |
| Rmi1 |
T |
A |
13: 58,557,156 (GRCm39) |
N468K |
probably benign |
Het |
| Rptor |
T |
A |
11: 119,494,751 (GRCm39) |
I39N |
probably benign |
Het |
| S1pr1 |
A |
G |
3: 115,505,628 (GRCm39) |
F322S |
probably damaging |
Het |
| Scgb1b10 |
T |
A |
7: 31,800,544 (GRCm39) |
Y44* |
probably null |
Het |
| Setx |
A |
G |
2: 29,038,114 (GRCm39) |
D1533G |
probably benign |
Het |
| Sf3b1 |
A |
G |
1: 55,029,508 (GRCm39) |
Y1165H |
probably damaging |
Het |
| Sgcz |
A |
T |
8: 38,420,103 (GRCm39) |
Y50N |
probably damaging |
Het |
| Sh3gl2 |
C |
A |
4: 85,305,817 (GRCm39) |
P227Q |
|
Het |
| She |
T |
C |
3: 89,759,795 (GRCm39) |
|
probably null |
Het |
| Slc9a4 |
T |
C |
1: 40,642,015 (GRCm39) |
I328T |
probably damaging |
Het |
| Sort1 |
G |
A |
3: 108,262,887 (GRCm39) |
|
probably null |
Het |
| Srebf1 |
A |
G |
11: 60,091,595 (GRCm39) |
S977P |
probably benign |
Het |
| Srsf9 |
T |
C |
5: 115,468,712 (GRCm39) |
V116A |
probably damaging |
Het |
| Tex15 |
G |
A |
8: 34,066,992 (GRCm39) |
V2141I |
possibly damaging |
Het |
| Tmprss13 |
A |
T |
9: 45,249,704 (GRCm39) |
H347L |
probably damaging |
Het |
| Trpv4 |
A |
G |
5: 114,768,511 (GRCm39) |
F519S |
probably benign |
Het |
| Trrap |
A |
G |
5: 144,758,649 (GRCm39) |
T2159A |
probably benign |
Het |
| Vmn1r36 |
A |
T |
6: 66,693,442 (GRCm39) |
Y144* |
probably null |
Het |
| Vmn2r10 |
A |
G |
5: 109,146,899 (GRCm39) |
I463T |
possibly damaging |
Het |
| Vps13a |
T |
A |
19: 16,641,186 (GRCm39) |
N2312I |
probably damaging |
Het |
| Wdr81 |
A |
T |
11: 75,343,919 (GRCm39) |
Y449* |
probably null |
Het |
| Zfhx3 |
A |
G |
8: 109,676,867 (GRCm39) |
D2639G |
possibly damaging |
Het |
| Zfp120 |
A |
G |
2: 149,959,995 (GRCm39) |
V131A |
probably benign |
Het |
| Zfp574 |
G |
T |
7: 24,780,562 (GRCm39) |
C528F |
probably damaging |
Het |
| Zfp947 |
A |
T |
17: 22,364,695 (GRCm39) |
N326K |
probably benign |
Het |
|
| Other mutations in Kif13a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01084:Kif13a
|
APN |
13 |
46,904,110 (GRCm39) |
splice site |
probably benign |
|
|
IGL01433:Kif13a
|
APN |
13 |
46,926,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01528:Kif13a
|
APN |
13 |
47,018,313 (GRCm39) |
splice site |
probably benign |
|
|
IGL01536:Kif13a
|
APN |
13 |
46,905,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01620:Kif13a
|
APN |
13 |
47,018,296 (GRCm39) |
missense |
probably benign |
|
|
IGL02020:Kif13a
|
APN |
13 |
46,947,495 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02142:Kif13a
|
APN |
13 |
46,925,011 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02375:Kif13a
|
APN |
13 |
46,978,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02407:Kif13a
|
APN |
13 |
46,938,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02476:Kif13a
|
APN |
13 |
46,938,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03038:Kif13a
|
APN |
13 |
46,926,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03053:Kif13a
|
APN |
13 |
46,905,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03366:Kif13a
|
APN |
13 |
46,918,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0025:Kif13a
|
UTSW |
13 |
46,939,987 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Kif13a
|
UTSW |
13 |
46,947,419 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0137:Kif13a
|
UTSW |
13 |
46,918,079 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0243:Kif13a
|
UTSW |
13 |
46,944,827 (GRCm39) |
missense |
probably benign |
0.24 |
|
R0346:Kif13a
|
UTSW |
13 |
46,967,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0403:Kif13a
|
UTSW |
13 |
46,944,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0492:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0607:Kif13a
|
UTSW |
13 |
46,956,187 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0631:Kif13a
|
UTSW |
13 |
46,932,364 (GRCm39) |
unclassified |
probably benign |
|
|
R0654:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0697:Kif13a
|
UTSW |
13 |
47,001,813 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0699:Kif13a
|
UTSW |
13 |
46,952,689 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0715:Kif13a
|
UTSW |
13 |
46,966,299 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Kif13a
|
UTSW |
13 |
46,967,712 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0903:Kif13a
|
UTSW |
13 |
47,082,735 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1419:Kif13a
|
UTSW |
13 |
46,978,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Kif13a
|
UTSW |
13 |
46,944,987 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Kif13a
|
UTSW |
13 |
46,966,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Kif13a
|
UTSW |
13 |
47,083,088 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1541:Kif13a
|
UTSW |
13 |
46,962,689 (GRCm39) |
missense |
probably benign |
|
|
R1579:Kif13a
|
UTSW |
13 |
46,906,332 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1582:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1752:Kif13a
|
UTSW |
13 |
46,951,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1755:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1755:Kif13a
|
UTSW |
13 |
46,906,089 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1858:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1891:Kif13a
|
UTSW |
13 |
47,082,695 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1902:Kif13a
|
UTSW |
13 |
46,941,638 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1928:Kif13a
|
UTSW |
13 |
46,966,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1961:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R2016:Kif13a
|
UTSW |
13 |
46,964,275 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2139:Kif13a
|
UTSW |
13 |
46,905,945 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Kif13a
|
UTSW |
13 |
46,922,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2407:Kif13a
|
UTSW |
13 |
46,930,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Kif13a
|
UTSW |
13 |
46,967,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3122:Kif13a
|
UTSW |
13 |
46,918,072 (GRCm39) |
splice site |
probably benign |
|
|
R3499:Kif13a
|
UTSW |
13 |
46,978,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3905:Kif13a
|
UTSW |
13 |
46,956,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Kif13a
|
UTSW |
13 |
46,967,631 (GRCm39) |
splice site |
probably null |
|
|
R4771:Kif13a
|
UTSW |
13 |
46,978,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Kif13a
|
UTSW |
13 |
46,980,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Kif13a
|
UTSW |
13 |
47,083,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4931:Kif13a
|
UTSW |
13 |
46,962,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4980:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4992:Kif13a
|
UTSW |
13 |
46,930,639 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5047:Kif13a
|
UTSW |
13 |
46,941,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5054:Kif13a
|
UTSW |
13 |
46,956,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5141:Kif13a
|
UTSW |
13 |
46,906,197 (GRCm39) |
missense |
probably benign |
|
|
R5329:Kif13a
|
UTSW |
13 |
46,928,877 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5429:Kif13a
|
UTSW |
13 |
46,926,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5499:Kif13a
|
UTSW |
13 |
46,986,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Kif13a
|
UTSW |
13 |
46,905,591 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5594:Kif13a
|
UTSW |
13 |
46,906,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Kif13a
|
UTSW |
13 |
46,978,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5964:Kif13a
|
UTSW |
13 |
46,925,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6115:Kif13a
|
UTSW |
13 |
46,954,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6317:Kif13a
|
UTSW |
13 |
46,980,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Kif13a
|
UTSW |
13 |
46,968,683 (GRCm39) |
splice site |
probably null |
|
|
R6393:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6394:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6395:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6735:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7037:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7038:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7039:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7237:Kif13a
|
UTSW |
13 |
46,962,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7285:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7286:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7287:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7341:Kif13a
|
UTSW |
13 |
46,980,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7693:Kif13a
|
UTSW |
13 |
46,904,089 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7761:Kif13a
|
UTSW |
13 |
46,951,955 (GRCm39) |
missense |
probably benign |
|
|
R8098:Kif13a
|
UTSW |
13 |
46,968,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Kif13a
|
UTSW |
13 |
46,932,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Kif13a
|
UTSW |
13 |
46,906,057 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8806:Kif13a
|
UTSW |
13 |
46,914,813 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8877:Kif13a
|
UTSW |
13 |
46,954,921 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8906:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9028:Kif13a
|
UTSW |
13 |
46,951,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kif13a
|
UTSW |
13 |
46,944,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9062:Kif13a
|
UTSW |
13 |
46,941,536 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9070:Kif13a
|
UTSW |
13 |
46,905,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9083:Kif13a
|
UTSW |
13 |
46,966,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9250:Kif13a
|
UTSW |
13 |
46,928,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Kif13a
|
UTSW |
13 |
46,951,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9360:Kif13a
|
UTSW |
13 |
46,962,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9369:Kif13a
|
UTSW |
13 |
46,940,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9589:Kif13a
|
UTSW |
13 |
46,956,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9749:Kif13a
|
UTSW |
13 |
46,914,227 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0013:Kif13a
|
UTSW |
13 |
47,082,746 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATCGGAACAGTGACCAATGG -3'
(R):5'- CAGGTTCTGGAAAGTCCTTTTC -3'
Sequencing Primer
(F):5'- CTCAGCTGTTAAGAGCACTGACTG -3'
(R):5'- GAAAGTCCTTTTCCATGATGGGCC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation