Incidental Mutation 'R8871:Bdp1'
| ID |
676312 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Bdp1
|
| Ensembl Gene |
ENSMUSG00000049658 |
| Gene Name |
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB |
| Synonyms |
Tfnr, TFIIIB90, TFC5, B130055N23Rik, TAF3B1, TFIIIB150, G630013P12Rik |
| MMRRC Submission |
068685-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8871 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
100154502-100240578 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 100186175 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glycine
at position 1759
(V1759G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105005
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038104]
[ENSMUST00000109379]
|
| AlphaFold |
Q571C7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038104
AA Change: V1759G
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000038321
Gene: ENSMUSG00000049658
AA Change: V1759G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
81 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
147 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
231 |
242 |
N/A |
INTRINSIC |
|
SANT
|
301 |
349 |
1.52e-4 |
SMART |
|
coiled coil region
|
375 |
399 |
N/A |
INTRINSIC |
|
coiled coil region
|
457 |
487 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
593 |
895 |
3.56e-18 |
PROSPERO |
|
coiled coil region
|
1013 |
1038 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1253 |
1612 |
3.56e-18 |
PROSPERO |
|
low complexity region
|
1718 |
1733 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1774 |
N/A |
INTRINSIC |
|
low complexity region
|
1912 |
1921 |
N/A |
INTRINSIC |
|
low complexity region
|
2185 |
2199 |
N/A |
INTRINSIC |
|
low complexity region
|
2335 |
2346 |
N/A |
INTRINSIC |
|
low complexity region
|
2398 |
2412 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099262
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000109379
AA Change: V1759G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000105005
Gene: ENSMUSG00000049658
AA Change: V1759G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
45 |
N/A |
INTRINSIC |
|
low complexity region
|
81 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
147 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
231 |
242 |
N/A |
INTRINSIC |
|
SANT
|
301 |
349 |
1.52e-4 |
SMART |
|
coiled coil region
|
457 |
487 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
593 |
895 |
4.79e-19 |
PROSPERO |
|
coiled coil region
|
1013 |
1038 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1253 |
1612 |
4.79e-19 |
PROSPERO |
|
low complexity region
|
1718 |
1733 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1774 |
N/A |
INTRINSIC |
|
low complexity region
|
1912 |
1921 |
N/A |
INTRINSIC |
|
low complexity region
|
2185 |
2199 |
N/A |
INTRINSIC |
|
low complexity region
|
2335 |
2346 |
N/A |
INTRINSIC |
|
low complexity region
|
2398 |
2412 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.3%
- 20x: 97.3%
|
| Validation Efficiency |
99% (76/77) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(4) : Gene trapped(4)
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
G |
11: 9,248,071 (GRCm39) |
M2606R |
probably benign |
Het |
| Abcg5 |
C |
T |
17: 84,990,295 (GRCm39) |
E3K |
probably benign |
Het |
| Adam20 |
A |
C |
8: 41,248,601 (GRCm39) |
H237P |
probably damaging |
Het |
| Alg3 |
T |
C |
16: 20,424,684 (GRCm39) |
Y361C |
probably damaging |
Het |
| Ano8 |
A |
T |
8: 71,931,944 (GRCm39) |
Y752N |
probably benign |
Het |
| AW551984 |
A |
T |
9: 39,500,998 (GRCm39) |
L759* |
probably null |
Het |
| Bicdl2 |
C |
A |
17: 23,885,777 (GRCm39) |
Q273K |
probably damaging |
Het |
| Cc2d2a |
A |
T |
5: 43,857,285 (GRCm39) |
T491S |
possibly damaging |
Het |
| Cdkl2 |
A |
G |
5: 92,164,989 (GRCm39) |
S545P |
possibly damaging |
Het |
| Ceacam5 |
T |
A |
7: 17,494,827 (GRCm39) |
I945K |
probably benign |
Het |
| Celf1 |
A |
G |
2: 90,840,840 (GRCm39) |
Y369C |
probably damaging |
Het |
| Cmtm1 |
TCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGG |
TCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGGCTGGCTGGTGTCCCGGGTACTGAAGGTCCCTGG |
8: 105,036,334 (GRCm39) |
|
probably null |
Het |
| Col14a1 |
T |
G |
15: 55,245,958 (GRCm39) |
D487E |
unknown |
Het |
| Crybg3 |
T |
C |
16: 59,378,519 (GRCm39) |
N912D |
probably benign |
Het |
| Cstl1 |
A |
G |
2: 148,596,554 (GRCm39) |
T86A |
probably damaging |
Het |
| Dixdc1 |
C |
T |
9: 50,595,096 (GRCm39) |
V482M |
possibly damaging |
Het |
| Dmbt1 |
T |
C |
7: 130,718,597 (GRCm39) |
Y1773H |
unknown |
Het |
| Dock4 |
T |
C |
12: 40,795,730 (GRCm39) |
I849T |
probably benign |
Het |
| Fbln2 |
A |
T |
6: 91,233,215 (GRCm39) |
|
probably null |
Het |
| Fbxo16 |
A |
G |
14: 65,531,348 (GRCm39) |
E84G |
probably damaging |
Het |
| Fras1 |
T |
A |
5: 96,855,257 (GRCm39) |
V1922D |
probably benign |
Het |
| G6pc3 |
A |
G |
11: 102,082,896 (GRCm39) |
H85R |
probably damaging |
Het |
| Galc |
A |
T |
12: 98,212,543 (GRCm39) |
N197K |
probably damaging |
Het |
| Galnt12 |
T |
G |
4: 47,108,582 (GRCm39) |
|
probably null |
Het |
| Gm10220 |
T |
A |
5: 26,322,863 (GRCm39) |
Q183L |
probably benign |
Het |
| Gxylt2 |
A |
G |
6: 100,760,109 (GRCm39) |
T215A |
probably damaging |
Het |
| Hnrnpf |
T |
G |
6: 117,900,811 (GRCm39) |
S32A |
probably benign |
Het |
| Hspa1l |
T |
C |
17: 35,197,799 (GRCm39) |
Y613H |
probably benign |
Het |
| Il1r2 |
T |
A |
1: 40,144,424 (GRCm39) |
V37D |
probably benign |
Het |
| Itga11 |
C |
A |
9: 62,668,823 (GRCm39) |
Y693* |
probably null |
Het |
| Itgax |
T |
A |
7: 127,735,223 (GRCm39) |
F459L |
probably damaging |
Het |
| Jph1 |
A |
G |
1: 17,067,719 (GRCm39) |
V656A |
possibly damaging |
Het |
| Kcnn4 |
A |
T |
7: 24,083,500 (GRCm39) |
I394F |
possibly damaging |
Het |
| Kdelr3 |
T |
A |
15: 79,410,044 (GRCm39) |
Y176* |
probably null |
Het |
| Kif13a |
T |
C |
13: 46,984,279 (GRCm39) |
D162G |
probably damaging |
Het |
| Klhdc8b |
G |
A |
9: 108,326,871 (GRCm39) |
P164S |
probably damaging |
Het |
| Lmbrd1 |
A |
T |
1: 24,783,435 (GRCm39) |
Q357L |
probably damaging |
Het |
| Lrrc37a |
T |
C |
11: 103,347,375 (GRCm39) |
M3107V |
unknown |
Het |
| Mllt3 |
ACTGCTGCTGCTGCTGCTGCTGCTACTGCTGCTGCTGCTGCTGCT |
ACTGCTGCTGCTGCTGCTGCTACTGCTGCTGCTGCTGCTGCT |
4: 87,759,552 (GRCm39) |
|
probably benign |
Het |
| Muc16 |
C |
A |
9: 18,567,344 (GRCm39) |
G1725V |
unknown |
Het |
| Myo5c |
T |
C |
9: 75,185,585 (GRCm39) |
S983P |
probably benign |
Het |
| Naip1 |
G |
A |
13: 100,580,146 (GRCm39) |
H217Y |
probably damaging |
Het |
| Nlrc3 |
T |
C |
16: 3,781,968 (GRCm39) |
|
probably benign |
Het |
| Nrl |
A |
T |
14: 55,758,184 (GRCm39) |
L181Q |
probably damaging |
Het |
| Olig1 |
T |
C |
16: 91,067,545 (GRCm39) |
*261R |
probably null |
Het |
| Or12k5 |
T |
C |
2: 36,895,060 (GRCm39) |
T189A |
probably benign |
Het |
| Or2l13b |
T |
C |
16: 19,349,536 (GRCm39) |
I45V |
|
Het |
| Or8j3c |
T |
C |
2: 86,253,697 (GRCm39) |
M108V |
probably benign |
Het |
| Oscp1 |
T |
A |
4: 125,952,535 (GRCm39) |
L21Q |
probably damaging |
Het |
| Oxct1 |
G |
A |
15: 4,064,763 (GRCm39) |
V34I |
probably benign |
Het |
| Pdzph1 |
A |
G |
17: 59,195,033 (GRCm39) |
L1074P |
probably damaging |
Het |
| Pkd1l1 |
T |
A |
11: 8,900,503 (GRCm39) |
S463C |
|
Het |
| Pnpla3 |
G |
A |
15: 84,063,509 (GRCm39) |
E296K |
probably benign |
Het |
| Prss35 |
T |
G |
9: 86,637,244 (GRCm39) |
L5V |
possibly damaging |
Het |
| Rbck1 |
T |
C |
2: 152,164,096 (GRCm39) |
E336G |
possibly damaging |
Het |
| Rgl2 |
G |
A |
17: 34,153,974 (GRCm39) |
R460Q |
probably damaging |
Het |
| Rmi1 |
T |
A |
13: 58,557,156 (GRCm39) |
N468K |
probably benign |
Het |
| Rptor |
T |
A |
11: 119,494,751 (GRCm39) |
I39N |
probably benign |
Het |
| S1pr1 |
A |
G |
3: 115,505,628 (GRCm39) |
F322S |
probably damaging |
Het |
| Scgb1b10 |
T |
A |
7: 31,800,544 (GRCm39) |
Y44* |
probably null |
Het |
| Setx |
A |
G |
2: 29,038,114 (GRCm39) |
D1533G |
probably benign |
Het |
| Sf3b1 |
A |
G |
1: 55,029,508 (GRCm39) |
Y1165H |
probably damaging |
Het |
| Sgcz |
A |
T |
8: 38,420,103 (GRCm39) |
Y50N |
probably damaging |
Het |
| Sh3gl2 |
C |
A |
4: 85,305,817 (GRCm39) |
P227Q |
|
Het |
| She |
T |
C |
3: 89,759,795 (GRCm39) |
|
probably null |
Het |
| Slc9a4 |
T |
C |
1: 40,642,015 (GRCm39) |
I328T |
probably damaging |
Het |
| Sort1 |
G |
A |
3: 108,262,887 (GRCm39) |
|
probably null |
Het |
| Srebf1 |
A |
G |
11: 60,091,595 (GRCm39) |
S977P |
probably benign |
Het |
| Srsf9 |
T |
C |
5: 115,468,712 (GRCm39) |
V116A |
probably damaging |
Het |
| Tex15 |
G |
A |
8: 34,066,992 (GRCm39) |
V2141I |
possibly damaging |
Het |
| Tmprss13 |
A |
T |
9: 45,249,704 (GRCm39) |
H347L |
probably damaging |
Het |
| Trpv4 |
A |
G |
5: 114,768,511 (GRCm39) |
F519S |
probably benign |
Het |
| Trrap |
A |
G |
5: 144,758,649 (GRCm39) |
T2159A |
probably benign |
Het |
| Vmn1r36 |
A |
T |
6: 66,693,442 (GRCm39) |
Y144* |
probably null |
Het |
| Vmn2r10 |
A |
G |
5: 109,146,899 (GRCm39) |
I463T |
possibly damaging |
Het |
| Vps13a |
T |
A |
19: 16,641,186 (GRCm39) |
N2312I |
probably damaging |
Het |
| Wdr81 |
A |
T |
11: 75,343,919 (GRCm39) |
Y449* |
probably null |
Het |
| Zfhx3 |
A |
G |
8: 109,676,867 (GRCm39) |
D2639G |
possibly damaging |
Het |
| Zfp120 |
A |
G |
2: 149,959,995 (GRCm39) |
V131A |
probably benign |
Het |
| Zfp574 |
G |
T |
7: 24,780,562 (GRCm39) |
C528F |
probably damaging |
Het |
| Zfp947 |
A |
T |
17: 22,364,695 (GRCm39) |
N326K |
probably benign |
Het |
|
| Other mutations in Bdp1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00088:Bdp1
|
APN |
13 |
100,235,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00096:Bdp1
|
APN |
13 |
100,197,373 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL00160:Bdp1
|
APN |
13 |
100,197,706 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00924:Bdp1
|
APN |
13 |
100,234,087 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01337:Bdp1
|
APN |
13 |
100,192,700 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01344:Bdp1
|
APN |
13 |
100,214,588 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01347:Bdp1
|
APN |
13 |
100,206,711 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01620:Bdp1
|
APN |
13 |
100,220,713 (GRCm39) |
splice site |
probably benign |
|
|
IGL01871:Bdp1
|
APN |
13 |
100,202,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02008:Bdp1
|
APN |
13 |
100,160,335 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02112:Bdp1
|
APN |
13 |
100,174,308 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02214:Bdp1
|
APN |
13 |
100,178,043 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02236:Bdp1
|
APN |
13 |
100,197,399 (GRCm39) |
missense |
probably benign |
|
|
IGL02307:Bdp1
|
APN |
13 |
100,229,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02364:Bdp1
|
APN |
13 |
100,191,816 (GRCm39) |
splice site |
probably benign |
|
|
IGL02415:Bdp1
|
APN |
13 |
100,225,916 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02601:Bdp1
|
APN |
13 |
100,235,022 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02605:Bdp1
|
APN |
13 |
100,214,623 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL02664:Bdp1
|
APN |
13 |
100,188,047 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02738:Bdp1
|
APN |
13 |
100,187,861 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL02754:Bdp1
|
APN |
13 |
100,197,481 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02967:Bdp1
|
APN |
13 |
100,178,778 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02974:Bdp1
|
APN |
13 |
100,191,800 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03156:Bdp1
|
APN |
13 |
100,197,544 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL03166:Bdp1
|
APN |
13 |
100,172,308 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL03232:Bdp1
|
APN |
13 |
100,187,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D3080:Bdp1
|
UTSW |
13 |
100,160,129 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0115:Bdp1
|
UTSW |
13 |
100,177,962 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0481:Bdp1
|
UTSW |
13 |
100,177,962 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0619:Bdp1
|
UTSW |
13 |
100,174,366 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0730:Bdp1
|
UTSW |
13 |
100,195,459 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Bdp1
|
UTSW |
13 |
100,172,333 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0833:Bdp1
|
UTSW |
13 |
100,172,333 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1307:Bdp1
|
UTSW |
13 |
100,186,271 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1325:Bdp1
|
UTSW |
13 |
100,235,516 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1346:Bdp1
|
UTSW |
13 |
100,215,263 (GRCm39) |
nonsense |
probably null |
|
|
R1644:Bdp1
|
UTSW |
13 |
100,197,448 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1670:Bdp1
|
UTSW |
13 |
100,163,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1836:Bdp1
|
UTSW |
13 |
100,171,653 (GRCm39) |
missense |
probably benign |
|
|
R1869:Bdp1
|
UTSW |
13 |
100,178,709 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1920:Bdp1
|
UTSW |
13 |
100,235,097 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1944:Bdp1
|
UTSW |
13 |
100,210,889 (GRCm39) |
splice site |
probably null |
|
|
R2030:Bdp1
|
UTSW |
13 |
100,197,697 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2069:Bdp1
|
UTSW |
13 |
100,187,496 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2180:Bdp1
|
UTSW |
13 |
100,197,913 (GRCm39) |
small insertion |
probably benign |
|
|
R2263:Bdp1
|
UTSW |
13 |
100,202,545 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2277:Bdp1
|
UTSW |
13 |
100,197,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2277:Bdp1
|
UTSW |
13 |
100,197,838 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2278:Bdp1
|
UTSW |
13 |
100,197,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2278:Bdp1
|
UTSW |
13 |
100,197,838 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2336:Bdp1
|
UTSW |
13 |
100,189,510 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2380:Bdp1
|
UTSW |
13 |
100,196,878 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3154:Bdp1
|
UTSW |
13 |
100,186,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4212:Bdp1
|
UTSW |
13 |
100,196,093 (GRCm39) |
missense |
probably benign |
|
|
R4322:Bdp1
|
UTSW |
13 |
100,228,731 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4414:Bdp1
|
UTSW |
13 |
100,167,369 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4415:Bdp1
|
UTSW |
13 |
100,167,369 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4764:Bdp1
|
UTSW |
13 |
100,192,775 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4766:Bdp1
|
UTSW |
13 |
100,186,376 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4888:Bdp1
|
UTSW |
13 |
100,187,627 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4914:Bdp1
|
UTSW |
13 |
100,192,844 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4917:Bdp1
|
UTSW |
13 |
100,191,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4918:Bdp1
|
UTSW |
13 |
100,191,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5170:Bdp1
|
UTSW |
13 |
100,167,302 (GRCm39) |
nonsense |
probably null |
|
|
R5266:Bdp1
|
UTSW |
13 |
100,204,043 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5312:Bdp1
|
UTSW |
13 |
100,234,109 (GRCm39) |
splice site |
probably null |
|
|
R5420:Bdp1
|
UTSW |
13 |
100,202,551 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5486:Bdp1
|
UTSW |
13 |
100,235,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Bdp1
|
UTSW |
13 |
100,228,794 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5913:Bdp1
|
UTSW |
13 |
100,187,612 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6018:Bdp1
|
UTSW |
13 |
100,174,732 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6037:Bdp1
|
UTSW |
13 |
100,163,957 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6037:Bdp1
|
UTSW |
13 |
100,163,957 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6700:Bdp1
|
UTSW |
13 |
100,162,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6969:Bdp1
|
UTSW |
13 |
100,211,039 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6972:Bdp1
|
UTSW |
13 |
100,174,269 (GRCm39) |
missense |
probably null |
1.00 |
|
R6996:Bdp1
|
UTSW |
13 |
100,180,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7043:Bdp1
|
UTSW |
13 |
100,215,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7060:Bdp1
|
UTSW |
13 |
100,196,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7105:Bdp1
|
UTSW |
13 |
100,206,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7155:Bdp1
|
UTSW |
13 |
100,197,659 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7175:Bdp1
|
UTSW |
13 |
100,186,478 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7177:Bdp1
|
UTSW |
13 |
100,186,478 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7327:Bdp1
|
UTSW |
13 |
100,178,040 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7512:Bdp1
|
UTSW |
13 |
100,187,457 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7562:Bdp1
|
UTSW |
13 |
100,162,049 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7583:Bdp1
|
UTSW |
13 |
100,186,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7788:Bdp1
|
UTSW |
13 |
100,191,759 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R7842:Bdp1
|
UTSW |
13 |
100,235,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7850:Bdp1
|
UTSW |
13 |
100,228,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7904:Bdp1
|
UTSW |
13 |
100,177,944 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7975:Bdp1
|
UTSW |
13 |
100,156,884 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7999:Bdp1
|
UTSW |
13 |
100,195,404 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8126:Bdp1
|
UTSW |
13 |
100,192,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8340:Bdp1
|
UTSW |
13 |
100,202,476 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8414:Bdp1
|
UTSW |
13 |
100,200,985 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8468:Bdp1
|
UTSW |
13 |
100,197,076 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8688:Bdp1
|
UTSW |
13 |
100,240,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8976:Bdp1
|
UTSW |
13 |
100,197,407 (GRCm39) |
nonsense |
probably null |
|
|
R8987:Bdp1
|
UTSW |
13 |
100,204,021 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9157:Bdp1
|
UTSW |
13 |
100,186,436 (GRCm39) |
missense |
probably benign |
0.40 |
|
R9437:Bdp1
|
UTSW |
13 |
100,162,158 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9612:Bdp1
|
UTSW |
13 |
100,214,370 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9679:Bdp1
|
UTSW |
13 |
100,180,285 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF003:Bdp1
|
UTSW |
13 |
100,196,958 (GRCm39) |
missense |
probably benign |
0.31 |
|
RF003:Bdp1
|
UTSW |
13 |
100,196,957 (GRCm39) |
missense |
probably benign |
0.31 |
|
Z1177:Bdp1
|
UTSW |
13 |
100,197,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTACGGTGTTCACTAAGTCCC -3'
(R):5'- GCGTGGATCAAAACGAATTCG -3'
Sequencing Primer
(F):5'- TTAAAGGGGTGAAAGTGCC -3'
(R):5'- CTGCTAAGAAGGAACCTAGAGCTTC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation